1300342:I596 RS15890
gene id: 1300342:I596_RS15890
uniprot id: A0A160DY80
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1300342:I596 RS09255
gene id: 1300342:I596_RS09255
uniprot id: A0A160DV94
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1300342:I596 RS06635
gene id: 1300342:I596_RS06635
uniprot id: A0A160DT07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1300342:I596 RS02635
gene id: 1300342:I596_RS02635
uniprot id: A0A167GIT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1300342:I596 RS03365
gene id: 1300342:I596_RS03365
uniprot id: A0A160DT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1300342:I596 RS04205
gene id: 1300342:I596_RS04205
uniprot id: A0A161HJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1300342:I596 RS02060
gene id: 1300342:I596_RS02060
uniprot id: A0A167GEW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1300342:I596 RS17045
gene id: 1300342:I596_RS17045
uniprot id: A0A160DZK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300342:I596 RS09855
gene id: 1300342:I596_RS09855
uniprot id: A0A160DV02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1300342:I596 RS01020
gene id: 1300342:I596_RS01020
uniprot id: A0A167G881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS04675
gene id: 1300342:I596_RS04675
uniprot id: A0A160DS08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1300342:I596 RS01660
gene id: 1300342:I596_RS01660
uniprot id: A0A167GC32
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1300342:I596 RS09530
gene id: 1300342:I596_RS09530
uniprot id: A0A160DUD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1300342:I596 RS13985
gene id: 1300342:I596_RS13985
uniprot id: A0A167H584
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1300342:I596 RS00205
gene id: 1300342:I596_RS00205
uniprot id: A0A167G2F5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1300342:I596 RS16535
gene id: 1300342:I596_RS16535
uniprot id: A0A160DYI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1300342:I596 RS15030
gene id: 1300342:I596_RS15030
uniprot id: A0A160DYM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1300342:I596 RS07420
gene id: 1300342:I596_RS07420
uniprot id: A0A160DUC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1300342:I596 RS08340
gene id: 1300342:I596_RS08340
uniprot id: A0A160DUA9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1300342:I596 RS11655
gene id: 1300342:I596_RS11655
uniprot id: A0A160DW91
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1300342:I596 RS08435
gene id: 1300342:I596_RS08435
uniprot id: A0A160DUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1300342:I596 RS14335
gene id: 1300342:I596_RS14335
uniprot id: A0A160DWM8
names: Similarity
messages: Belongs to the peptidase S9C family.

1300342:I596 RS04725
gene id: 1300342:I596_RS04725
uniprot id: A0A167GQ35
names: Similarity
messages: Belongs to the HIBADH-related family.

1300342:I596 RS00485
gene id: 1300342:I596_RS00485
uniprot id: A0A167G4B0
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS02980
gene id: 1300342:I596_RS02980
uniprot id: A0A167GKX1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1300342:I596 RS08995
gene id: 1300342:I596_RS08995
uniprot id: A0A160DV14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1300342:I596 RS01715
gene id: 1300342:I596_RS01715
uniprot id: A0A167GCH5
names: Similarity
messages: Belongs to the YciI family.

1300342:I596 RS16525
gene id: 1300342:I596_RS16525
uniprot id: A0A160DXQ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS02130
gene id: 1300342:I596_RS02130
uniprot id: A0A167GFF5
names: Similarity
messages: Belongs to the DprA/Smf family.

1300342:I596 RS14345
gene id: 1300342:I596_RS14345
uniprot id: A0A160DXH5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1300342:I596 RS14730
gene id: 1300342:I596_RS14730
uniprot id: A0A160DXN4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1300342:I596 RS15985
gene id: 1300342:I596_RS15985
uniprot id: A0A160DZ02
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS07435
gene id: 1300342:I596_RS07435
uniprot id: A0A160DTS9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1300342:I596 RS09085
gene id: 1300342:I596_RS09085
uniprot id: A0A160DU58
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1300342:I596 RS14150
gene id: 1300342:I596_RS14150
uniprot id: A0A160DWJ7
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS09200
gene id: 1300342:I596_RS09200
uniprot id: A0A160DV86
names: Similarity
messages: Belongs to the peptidase M13 family.

1300342:I596 RS18730
gene id: 1300342:I596_RS18730
uniprot id: A0A160DT73
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

1300342:I596 RS04490
gene id: 1300342:I596_RS04490
uniprot id: A0A160DRY3
names: Subcellular Location Annotation
messages: Nucleus

1300342:I596 RS03440
gene id: 1300342:I596_RS03440
uniprot id: A0A160DRJ9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1300342:I596 RS01600
gene id: 1300342:I596_RS01600
uniprot id: A0A167GBS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1300342:I596 RS17885
gene id: 1300342:I596_RS17885
uniprot id: A0A161HS30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1300342:I596 RS13045
gene id: 1300342:I596_RS13045
uniprot id: A0A160DW16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1300342:I596 RS03595
gene id: 1300342:I596_RS03595
uniprot id: A0A160DRL3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300342:I596 RS15265
gene id: 1300342:I596_RS15265
uniprot id: A0A160DXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS12990
gene id: 1300342:I596_RS12990
uniprot id: A0A160DWG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1300342:I596 RS10025
gene id: 1300342:I596_RS10025
uniprot id: A0A160DWB7
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1300342:I596 RS08625
gene id: 1300342:I596_RS08625
uniprot id: A0A160DUV1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1300342:I596 RS03965
gene id: 1300342:I596_RS03965
uniprot id: A0A161HJJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS04415
gene id: 1300342:I596_RS04415
uniprot id: A0A160DSU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1300342:I596 RS12265
gene id: 1300342:I596_RS12265
uniprot id: A0A160DWI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1300342:I596 RS14140
gene id: 1300342:I596_RS14140
uniprot id: A0A160DWK2
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1300342:I596 RS07500
gene id: 1300342:I596_RS07500
uniprot id: A0A160DTF4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1300342:I596 RS06170
gene id: 1300342:I596_RS06170
uniprot id: A0A167GS33
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1300342:I596 RS02935
gene id: 1300342:I596_RS02935
uniprot id: A0A167GKL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1300342:I596 RS13970
gene id: 1300342:I596_RS13970
uniprot id: A0A160DY73
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1300342:I596 RS11015
gene id: 1300342:I596_RS11015
uniprot id: A0A167H0G0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1300342:I596 RS16060
gene id: 1300342:I596_RS16060
uniprot id: A0A160DXH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1300342:I596 RS17860
gene id: 1300342:I596_RS17860
uniprot id: A0A167HC87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1300342:I596 RS16515
gene id: 1300342:I596_RS16515
uniprot id: A0A160DXP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1300342:I596 RS14955
gene id: 1300342:I596_RS14955
uniprot id: A0A160DWY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1300342:I596 RS17265
gene id: 1300342:I596_RS17265
uniprot id: A0A167HA31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS03690
gene id: 1300342:I596_RS03690
uniprot id: A0A160DRM4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1300342:I596 RS01955
gene id: 1300342:I596_RS01955
uniprot id: A0A167GE22
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1300342:I596 RS15545
gene id: 1300342:I596_RS15545
uniprot id: A0A160DX86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS07875
gene id: 1300342:I596_RS07875
uniprot id: A0A160DU15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1300342:I596 RS04790
gene id: 1300342:I596_RS04790
uniprot id: A0A160DS47
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1300342:I596 RS04470
gene id: 1300342:I596_RS04470
uniprot id: A0A160DTQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1300342:I596 RS00575
gene id: 1300342:I596_RS00575
uniprot id: A0A167G4U5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS07860
gene id: 1300342:I596_RS07860
uniprot id: A0A160DUJ9
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

1300342:I596 RS04930
gene id: 1300342:I596_RS04930
uniprot id: A0A160DS56
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1300342:I596 RS10865
gene id: 1300342:I596_RS10865
uniprot id: A0A160DUZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1300342:I596 RS09910
gene id: 1300342:I596_RS09910
uniprot id: A0A160DUK1
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1300342:I596 RS17420
gene id: 1300342:I596_RS17420
uniprot id: A0A160DY52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1300342:I596 RS08110
gene id: 1300342:I596_RS08110
uniprot id: A0A161HR27
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1300342:I596 RS12545
gene id: 1300342:I596_RS12545
uniprot id: A0A161HRH6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1300342:I596 RS10320
gene id: 1300342:I596_RS10320
uniprot id: A0A160DWG1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1300342:I596 RS13010
gene id: 1300342:I596_RS13010
uniprot id: A0A160DW14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1300342:I596 RS17055
gene id: 1300342:I596_RS17055
uniprot id: A0A160DXZ7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1300342:I596 RS08250
gene id: 1300342:I596_RS08250
uniprot id: A0A167GVJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1300342:I596 RS04325
gene id: 1300342:I596_RS04325
uniprot id: A0A160DSR9
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1300342:I596 RS04030
gene id: 1300342:I596_RS04030
uniprot id: A0A160DRR4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1300342:I596 RS16145
gene id: 1300342:I596_RS16145
uniprot id: A0A167H8E6
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

1300342:I596 RS07590
gene id: 1300342:I596_RS07590
uniprot id: A0A167GUA2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1300342:I596 RS14420
gene id: 1300342:I596_RS14420
uniprot id: A0A160DWN3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1300342:I596 RS17080
gene id: 1300342:I596_RS17080
uniprot id: A0A160DYP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1300342:I596 RS06855
gene id: 1300342:I596_RS06855
uniprot id: A0A160DUV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS09295
gene id: 1300342:I596_RS09295
uniprot id: A0A160DUB0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1300342:I596 RS15170
gene id: 1300342:I596_RS15170
uniprot id: A0A161HRQ0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1300342:I596 RS12250
gene id: 1300342:I596_RS12250
uniprot id: A0A160DVN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1300342:I596 RS14750
gene id: 1300342:I596_RS14750
uniprot id: A0A160DX96
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS07965
gene id: 1300342:I596_RS07965
uniprot id: A0A167GUV5
names: Similarity
messages: Belongs to the peptidase U62 family.

1300342:I596 RS15690
gene id: 1300342:I596_RS15690
uniprot id: A0A160DXB0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1300342:I596 RS15735
gene id: 1300342:I596_RS15735
uniprot id: A0A160DXC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1300342:I596 RS10065
gene id: 1300342:I596_RS10065
uniprot id: A0A161HRB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.

1300342:I596 RS03345
gene id: 1300342:I596_RS03345
uniprot id: A0A160DRJ1
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS11650
gene id: 1300342:I596_RS11650
uniprot id: A0A160DVE1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS11840
gene id: 1300342:I596_RS11840
uniprot id: A0A160DVG4
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1300342:I596 RS04230
gene id: 1300342:I596_RS04230
uniprot id: A0A167GP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1300342:I596 RS16195
gene id: 1300342:I596_RS16195
uniprot id: A0A167H8H7
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS11670
gene id: 1300342:I596_RS11670
uniprot id: A0A160DX33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1300342:I596 RS03135
gene id: 1300342:I596_RS03135
uniprot id: A0A167GLZ0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1300342:I596 RS07360
gene id: 1300342:I596_RS07360
uniprot id: A0A160DTE0
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1300342:I596 RS13250
gene id: 1300342:I596_RS13250
uniprot id: A0A160DW52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS02765
gene id: 1300342:I596_RS02765
uniprot id: A0A167GJJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1300342:I596 RS01505
gene id: 1300342:I596_RS01505
uniprot id: A0A167GB06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS14755
gene id: 1300342:I596_RS14755
uniprot id: A0A160DWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1300342:I596 RS07880
gene id: 1300342:I596_RS07880
uniprot id: A0A160DTM0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1300342:I596 RS02620
gene id: 1300342:I596_RS02620
uniprot id: A0A167GIP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1300342:I596 RS06360
gene id: 1300342:I596_RS06360
uniprot id: A0A167GSL4
names: Similarity
messages: Belongs to the YfgM family.

1300342:I596 RS03040
gene id: 1300342:I596_RS03040
uniprot id: A0A161HJC8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS07720
gene id: 1300342:I596_RS07720
uniprot id: A0A160DVA0
names: Similarity
messages: Belongs to the SCO1/2 family.

1300342:I596 RS14180
gene id: 1300342:I596_RS14180
uniprot id: A0A167H5J4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1300342:I596 RS12195
gene id: 1300342:I596_RS12195
uniprot id: A0A167H2G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1300342:I596 RS14740
gene id: 1300342:I596_RS14740
uniprot id: A0A167H693
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1300342:I596 RS12665
gene id: 1300342:I596_RS12665
uniprot id: A0A160DVT7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1300342:I596 RS10575
gene id: 1300342:I596_RS10575
uniprot id: A0A160DUU7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1300342:I596 RS03140
gene id: 1300342:I596_RS03140
uniprot id: A0A167GLZ6
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS09650
gene id: 1300342:I596_RS09650
uniprot id: A0A160DW59
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS11850
gene id: 1300342:I596_RS11850
uniprot id: A0A160DVH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS17020
gene id: 1300342:I596_RS17020
uniprot id: A0A167H9T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1300342:I596 RS10540
gene id: 1300342:I596_RS10540
uniprot id: A0A160DUT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1300342:I596 RS01350
gene id: 1300342:I596_RS01350
uniprot id: A0A167GA04
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS08335
gene id: 1300342:I596_RS08335
uniprot id: A0A160DVK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1300342:I596 RS12575
gene id: 1300342:I596_RS12575
uniprot id: A0A160DVT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1300342:I596 RS09735
gene id: 1300342:I596_RS09735
uniprot id: A0A160DVC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1300342:I596 RS01585
gene id: 1300342:I596_RS01585
uniprot id: A0A167GBN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1300342:I596 RS09030
gene id: 1300342:I596_RS09030
uniprot id: A0A160DU56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1300342:I596 RS15800
gene id: 1300342:I596_RS15800
uniprot id: A0A160DY64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1300342:I596 RS12540
gene id: 1300342:I596_RS12540
uniprot id: A0A160DWR6
names: Similarity
messages: Belongs to the RutC family.

1300342:I596 RS15740
gene id: 1300342:I596_RS15740
uniprot id: A0A160DXB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1300342:I596 RS02930
gene id: 1300342:I596_RS02930
uniprot id: A0A167GKK2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1300342:I596 RS04460
gene id: 1300342:I596_RS04460
uniprot id: A0A160DSU8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1300342:I596 RS12595
gene id: 1300342:I596_RS12595
uniprot id: A0A167H349
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1300342:I596 RS16280
gene id: 1300342:I596_RS16280
uniprot id: A0A160DY14
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1300342:I596 RS12240
gene id: 1300342:I596_RS12240
uniprot id: A0A160DVM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1300342:I596 RS16065
gene id: 1300342:I596_RS16065
uniprot id: A0A160DYA4
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS02255
gene id: 1300342:I596_RS02255
uniprot id: A0A167GGD3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS02890
gene id: 1300342:I596_RS02890
uniprot id: A0A167GKD1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1300342:I596 RS10005
gene id: 1300342:I596_RS10005
uniprot id: A0A160DUL9
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1300342:I596 RS14650
gene id: 1300342:I596_RS14650
uniprot id: A0A160DYI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS15235
gene id: 1300342:I596_RS15235
uniprot id: A0A160DX29
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1300342:I596 RS16425
gene id: 1300342:I596_RS16425
uniprot id: A0A167H8Z8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1300342:I596 RS15145
gene id: 1300342:I596_RS15145
uniprot id: A0A160DX12
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300342:I596 RS05140
gene id: 1300342:I596_RS05140
uniprot id: A0A167GQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS13890
gene id: 1300342:I596_RS13890
uniprot id: A0A160DWE1
names: Similarity
messages: Belongs to the GST superfamily.

1300342:I596 RS00475
gene id: 1300342:I596_RS00475
uniprot id: A0A167G491
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1300342:I596 RS14300
gene id: 1300342:I596_RS14300
uniprot id: A0A160DXK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1300342:I596 RS03565
gene id: 1300342:I596_RS03565
uniprot id: A0A167GN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS08635
gene id: 1300342:I596_RS08635
uniprot id: A0A167GW71
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1300342:I596 RS17160
gene id: 1300342:I596_RS17160
uniprot id: A0A167H9Y6
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS12315
gene id: 1300342:I596_RS12315
uniprot id: A0A160DWK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1300342:I596 RS11030
gene id: 1300342:I596_RS11030
uniprot id: A0A160DV37
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS15560
gene id: 1300342:I596_RS15560
uniprot id: A0A160DY25
names: Similarity
messages: Belongs to the peptidase M16 family.

1300342:I596 RS09130
gene id: 1300342:I596_RS09130
uniprot id: A0A160DU72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1300342:I596 RS05325
gene id: 1300342:I596_RS05325
uniprot id: A0A160DU48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1300342:I596 RS10820
gene id: 1300342:I596_RS10820
uniprot id: A0A167GZZ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS17425
gene id: 1300342:I596_RS17425
uniprot id: A0A160DYR1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1300342:I596 RS06495
gene id: 1300342:I596_RS06495
uniprot id: A0A160DTW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300342:I596 RS12020
gene id: 1300342:I596_RS12020
uniprot id: A0A160DWE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300342:I596 RS07280
gene id: 1300342:I596_RS07280
uniprot id: A0A160DTC4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1300342:I596 RS03710
gene id: 1300342:I596_RS03710
uniprot id: A0A160DTC9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1300342:I596 RS16550
gene id: 1300342:I596_RS16550
uniprot id: A0A160DZB1
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1300342:I596 RS02625
gene id: 1300342:I596_RS02625
uniprot id: A0A167GIR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS06195
gene id: 1300342:I596_RS06195
uniprot id: A0A160DST2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300342:I596 RS10410
gene id: 1300342:I596_RS10410
uniprot id: A0A160DVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS12305
gene id: 1300342:I596_RS12305
uniprot id: A0A160DVP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1300342:I596 RS12525
gene id: 1300342:I596_RS12525
uniprot id: A0A160DVS6
names: Similarity
messages: Belongs to the MlaA family.

1300342:I596 RS16835
gene id: 1300342:I596_RS16835
uniprot id: A0A160DXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1300342:I596 RS06125
gene id: 1300342:I596_RS06125
uniprot id: A0A160DT64
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1300342:I596 RS06510
gene id: 1300342:I596_RS06510
uniprot id: A0A160DUP6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1300342:I596 RS10560
gene id: 1300342:I596_RS10560
uniprot id: A0A161HRC9
names: Similarity
messages: Belongs to the TrpC family.

1300342:I596 RS01100
gene id: 1300342:I596_RS01100
uniprot id: A0A161HIN5
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1300342:I596 RS09300
gene id: 1300342:I596_RS09300
uniprot id: A0A160DV60
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1300342:I596 RS13395
gene id: 1300342:I596_RS13395
uniprot id: A0A160DX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS10470
gene id: 1300342:I596_RS10470
uniprot id: A0A160DWI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1300342:I596 RS13780
gene id: 1300342:I596_RS13780
uniprot id: A0A167H4V4
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS13980
gene id: 1300342:I596_RS13980
uniprot id: A0A160DWF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1300342:I596 RS07510
gene id: 1300342:I596_RS07510
uniprot id: A0A160DTG4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS02835
gene id: 1300342:I596_RS02835
uniprot id: A0A167GK25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

1300342:I596 RS17115
gene id: 1300342:I596_RS17115
uniprot id: A0A160DY12
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1300342:I596 RS00640
gene id: 1300342:I596_RS00640
uniprot id: A0A167G5C6
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS14490
gene id: 1300342:I596_RS14490
uniprot id: A0A160DXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1300342:I596 RS11275
gene id: 1300342:I596_RS11275
uniprot id: A0A160DWW7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1300342:I596 RS10125
gene id: 1300342:I596_RS10125
uniprot id: A0A160DV41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1300342:I596 RS16275
gene id: 1300342:I596_RS16275
uniprot id: A0A160DZ58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1300342:I596 RS12355
gene id: 1300342:I596_RS12355
uniprot id: A0A160DVP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1300342:I596 RS08515
gene id: 1300342:I596_RS08515
uniprot id: A0A160DTW6
names: Similarity
messages: Belongs to the ArsC family.

1300342:I596 RS07890
gene id: 1300342:I596_RS07890
uniprot id: A0A160DTL7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1300342:I596 RS09955
gene id: 1300342:I596_RS09955
uniprot id: A0A160DV19
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1300342:I596 RS06725
gene id: 1300342:I596_RS06725
uniprot id: A0A161HJR5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS09125
gene id: 1300342:I596_RS09125
uniprot id: A0A167GWZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1300342:I596 RS07460
gene id: 1300342:I596_RS07460
uniprot id: A0A160DTF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1300342:I596 RS12775
gene id: 1300342:I596_RS12775
uniprot id: A0A160DVX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS17095
gene id: 1300342:I596_RS17095
uniprot id: A0A160DZL2
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1300342:I596 RS14435
gene id: 1300342:I596_RS14435
uniprot id: A0A160DWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1300342:I596 RS16615
gene id: 1300342:I596_RS16615
uniprot id: A0A167H987
names: Similarity
messages: Belongs to the AHA1 family.

1300342:I596 RS12180
gene id: 1300342:I596_RS12180
uniprot id: A0A160DXB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1300342:I596 RS16165
gene id: 1300342:I596_RS16165
uniprot id: A0A160DYB8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1300342:I596 RS12655
gene id: 1300342:I596_RS12655
uniprot id: A0A160DWA0
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1300342:I596 RS06785
gene id: 1300342:I596_RS06785
uniprot id: A0A160DT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1300342:I596 RS10270
gene id: 1300342:I596_RS10270
uniprot id: A0A160DWF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1300342:I596 RS15905
gene id: 1300342:I596_RS15905
uniprot id: A0A160DYY3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1300342:I596 RS08560
gene id: 1300342:I596_RS08560
uniprot id: A0A160DTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1300342:I596 RS06135
gene id: 1300342:I596_RS06135
uniprot id: A0A167GS23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1300342:I596 RS08600
gene id: 1300342:I596_RS08600
uniprot id: A0A160DTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1300342:I596 RS09220
gene id: 1300342:I596_RS09220
uniprot id: A0A160DU90
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS16075
gene id: 1300342:I596_RS16075
uniprot id: A0A161HRS8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS09195
gene id: 1300342:I596_RS09195
uniprot id: A0A160DV44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1300342:I596 RS11360
gene id: 1300342:I596_RS11360
uniprot id: A0A167H0Z7
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS05160
gene id: 1300342:I596_RS05160
uniprot id: A0A160DS98
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1300342:I596 RS01225
gene id: 1300342:I596_RS01225
uniprot id: A0A167G9E9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS14380
gene id: 1300342:I596_RS14380
uniprot id: A0A160DWP3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1300342:I596 RS12385
gene id: 1300342:I596_RS12385
uniprot id: A0A160DXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1300342:I596 RS16110
gene id: 1300342:I596_RS16110
uniprot id: A0A160DXI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS12350
gene id: 1300342:I596_RS12350
uniprot id: A0A160DVP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1300342:I596 RS04055
gene id: 1300342:I596_RS04055
uniprot id: A0A160DSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1300342:I596 RS14130
gene id: 1300342:I596_RS14130
uniprot id: A0A160DWI2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS01105
gene id: 1300342:I596_RS01105
uniprot id: A0A167G8R2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300342:I596 RS06325
gene id: 1300342:I596_RS06325
uniprot id: A0A160DSW9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300342:I596 RS08545
gene id: 1300342:I596_RS08545
uniprot id: A0A160DUE4
names: Similarity
messages: Belongs to the BolA/IbaG family.

1300342:I596 RS09165
gene id: 1300342:I596_RS09165
uniprot id: A0A160DUP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300342:I596 RS09435
gene id: 1300342:I596_RS09435
uniprot id: A0A160DUD5
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1300342:I596 RS11105
gene id: 1300342:I596_RS11105
uniprot id: A0A160DV43
names: Similarity
messages: Belongs to the ApbE family.

1300342:I596 RS13815
gene id: 1300342:I596_RS13815
uniprot id: A0A160DX90
names: Similarity
messages: Belongs to the malic enzymes family.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1300342:I596 RS14360
gene id: 1300342:I596_RS14360
uniprot id: A0A160DYD6
names: Similarity
messages: Belongs to the peptidase S41A family.

1300342:I596 RS08370
gene id: 1300342:I596_RS08370
uniprot id: A0A160DUR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300342:I596 RS10040
gene id: 1300342:I596_RS10040
uniprot id: A0A167GYD7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1300342:I596 RS09355
gene id: 1300342:I596_RS09355
uniprot id: A0A160DVB0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1300342:I596 RS10920
gene id: 1300342:I596_RS10920
uniprot id: A0A167H083
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300342:I596 RS09595
gene id: 1300342:I596_RS09595
uniprot id: A0A167GXR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1300342:I596 RS04130
gene id: 1300342:I596_RS04130
uniprot id: A0A160DRS0
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1300342:I596 RS05370
gene id: 1300342:I596_RS05370
uniprot id: A0A167GR05
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300342:I596 RS09915
gene id: 1300342:I596_RS09915
uniprot id: A0A167GY65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1300342:I596 RS11640
gene id: 1300342:I596_RS11640
uniprot id: A0A160DVD4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1300342:I596 RS00145
gene id: 1300342:I596_RS00145
uniprot id: A0A161HIE2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1300342:I596 RS17320
gene id: 1300342:I596_RS17320
uniprot id: A0A160DY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1300342:I596 RS12580
gene id: 1300342:I596_RS12580
uniprot id: A0A160DVU2
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1300342:I596 RS06260
gene id: 1300342:I596_RS06260
uniprot id: A0A160DTR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1300342:I596 RS13940
gene id: 1300342:I596_RS13940
uniprot id: A0A167H573
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS01365
gene id: 1300342:I596_RS01365
uniprot id: A0A167GA43
names: Similarity
messages: Belongs to the GST superfamily.

1300342:I596 RS14960
gene id: 1300342:I596_RS14960
uniprot id: A0A160DXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1300342:I596 RS14085
gene id: 1300342:I596_RS14085
uniprot id: A0A167H5E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1300342:I596 RS13585
gene id: 1300342:I596_RS13585
uniprot id: A0A160DX99
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1300342:I596 RS15465
gene id: 1300342:I596_RS15465
uniprot id: A0A160DX76
names: Caution
names: Similarity
messages: Belongs to the intimin/invasin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS03715
gene id: 1300342:I596_RS03715
uniprot id: A0A160DS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1300342:I596 RS04665
gene id: 1300342:I596_RS04665
uniprot id: A0A160DS15
names: Similarity
messages: Belongs to the YicC/YloC family.

1300342:I596 RS12130
gene id: 1300342:I596_RS12130
uniprot id: A0A160DXA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1300342:I596 RS07725
gene id: 1300342:I596_RS07725
uniprot id: A0A160DTZ0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1300342:I596 RS06080
gene id: 1300342:I596_RS06080
uniprot id: A0A167GS09
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS06245
gene id: 1300342:I596_RS06245
uniprot id: A0A160DSU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1300342:I596 RS15475
gene id: 1300342:I596_RS15475
uniprot id: A0A160DY55
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1300342:I596 RS06995
gene id: 1300342:I596_RS06995
uniprot id: A0A167GTE1
names: Similarity
messages: Belongs to the YciI family.

1300342:I596 RS11590
gene id: 1300342:I596_RS11590
uniprot id: A0A160DVC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1300342:I596 RS03465
gene id: 1300342:I596_RS03465
uniprot id: A0A167GN18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1300342:I596 RS03275
gene id: 1300342:I596_RS03275
uniprot id: A0A160DT59
names: Similarity
messages: Belongs to the GSP E family.

1300342:I596 RS00040
gene id: 1300342:I596_RS00040
uniprot id: A0A170R0R8
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS04855
gene id: 1300342:I596_RS04855
uniprot id: A0A160DT20
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

1300342:I596 RS14000
gene id: 1300342:I596_RS14000
uniprot id: A0A160DWH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1300342:I596 RS16155
gene id: 1300342:I596_RS16155
uniprot id: A0A160DXJ0
names: Similarity
messages: Belongs to the UPF0758 family.

1300342:I596 RS08520
gene id: 1300342:I596_RS08520
uniprot id: A0A160DTY2
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

1300342:I596 RS07355
gene id: 1300342:I596_RS07355
uniprot id: A0A160DTC6
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1300342:I596 RS15720
gene id: 1300342:I596_RS15720
uniprot id: A0A160DXR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1300342:I596 RS08040
gene id: 1300342:I596_RS08040
uniprot id: A0A160DTP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1300342:I596 RS12365
gene id: 1300342:I596_RS12365
uniprot id: A0A160DWK5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1300342:I596 RS15345
gene id: 1300342:I596_RS15345
uniprot id: A0A160DYR3
names: Subcellular Location Annotation
messages: Cytoplasm

1300342:I596 RS12050
gene id: 1300342:I596_RS12050
uniprot id: A0A167H257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300342:I596 RS05350
gene id: 1300342:I596_RS05350
uniprot id: A0A160DSC8
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1300342:I596 RS00985
gene id: 1300342:I596_RS00985
uniprot id: A0A167G802
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1300342:I596 RS07255
gene id: 1300342:I596_RS07255
uniprot id: A0A160DTP6
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1300342:I596 RS06935
gene id: 1300342:I596_RS06935
uniprot id: A0A160DU22
names: Similarity
messages: Belongs to the CFA/CMAS family.

1300342:I596 RS13965
gene id: 1300342:I596_RS13965
uniprot id: A0A161HRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1300342:I596 RS16090
gene id: 1300342:I596_RS16090
uniprot id: A0A160DXH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1300342:I596 RS09540
gene id: 1300342:I596_RS09540
uniprot id: A0A160DV99
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1300342:I596 RS12200
gene id: 1300342:I596_RS12200
uniprot id: A0A160DVM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1300342:I596 RS00715
gene id: 1300342:I596_RS00715
uniprot id: A0A167G5Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1300342:I596 RS16390
gene id: 1300342:I596_RS16390
uniprot id: A0A167H8X6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1300342:I596 RS13430
gene id: 1300342:I596_RS13430
uniprot id: A0A160DW79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1300342:I596 RS12880
gene id: 1300342:I596_RS12880
uniprot id: A0A160DWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS02970
gene id: 1300342:I596_RS02970
uniprot id: A0A167GKU3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1300342:I596 RS05345
gene id: 1300342:I596_RS05345
uniprot id: A0A160DSD2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1300342:I596 RS17620
gene id: 1300342:I596_RS17620
uniprot id: A0A167HAW2
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1300342:I596 RS15990
gene id: 1300342:I596_RS15990
uniprot id: A0A160DXW5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1300342:I596 RS02525
gene id: 1300342:I596_RS02525
uniprot id: A0A167GI29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1300342:I596 RS09390
gene id: 1300342:I596_RS09390
uniprot id: A0A160DUC8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300342:I596 RS00160
gene id: 1300342:I596_RS00160
uniprot id: A0A167G255
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS12370
gene id: 1300342:I596_RS12370
uniprot id: A0A160DWP0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1300342:I596 RS10665
gene id: 1300342:I596_RS10665
uniprot id: A0A160DUW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1300342:I596 RS09820
gene id: 1300342:I596_RS09820
uniprot id: A0A160DUH6
names: Subcellular Location Annotation
messages: Cytoplasm

1300342:I596 RS09045
gene id: 1300342:I596_RS09045
uniprot id: A0A160DV21
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1300342:I596 RS00585
gene id: 1300342:I596_RS00585
uniprot id: A0A167G4W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS08955
gene id: 1300342:I596_RS08955
uniprot id: A0A167GWP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1300342:I596 RS01340
gene id: 1300342:I596_RS01340
uniprot id: A0A167G9Z4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1300342:I596 RS07640
gene id: 1300342:I596_RS07640
uniprot id: A0A160DTH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1300342:I596 RS14720
gene id: 1300342:I596_RS14720
uniprot id: A0A160DWU0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1300342:I596 RS05125
gene id: 1300342:I596_RS05125
uniprot id: A0A160DS94
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1300342:I596 RS09115
gene id: 1300342:I596_RS09115
uniprot id: A0A160DUN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1300342:I596 RS12475
gene id: 1300342:I596_RS12475
uniprot id: A0A160DVR8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1300342:I596 RS12860
gene id: 1300342:I596_RS12860
uniprot id: A0A160DVY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1300342:I596 RS04270
gene id: 1300342:I596_RS04270
uniprot id: A0A160DSR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1300342:I596 RS02540
gene id: 1300342:I596_RS02540
uniprot id: A0A167GI59
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1300342:I596 RS13475
gene id: 1300342:I596_RS13475
uniprot id: A0A160DW88
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300342:I596 RS17520
gene id: 1300342:I596_RS17520
uniprot id: A0A160DY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1300342:I596 RS08645
gene id: 1300342:I596_RS08645
uniprot id: A0A160DUG3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1300342:I596 RS06760
gene id: 1300342:I596_RS06760
uniprot id: A0A160DTH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1300342:I596 RS12255
gene id: 1300342:I596_RS12255
uniprot id: A0A160DVN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1300342:I596 RS00720
gene id: 1300342:I596_RS00720
uniprot id: A0A161HIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1300342:I596 RS05920
gene id: 1300342:I596_RS05920
uniprot id: A0A167GRU3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS12630
gene id: 1300342:I596_RS12630
uniprot id: A0A160DVV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1300342:I596 RS02495
gene id: 1300342:I596_RS02495
uniprot id: A0A167GHU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1300342:I596 RS03685
gene id: 1300342:I596_RS03685
uniprot id: A0A160DRM3
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1300342:I596 RS00395
gene id: 1300342:I596_RS00395
uniprot id: A0A167G3Q2
names: Cofactor
messages: Can also use Mn(2+) ion.

1300342:I596 RS16100
gene id: 1300342:I596_RS16100
uniprot id: A0A160DXI8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1300342:I596 RS05295
gene id: 1300342:I596_RS05295
uniprot id: A0A160DSC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS10670
gene id: 1300342:I596_RS10670
uniprot id: A0A167GZS6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1300342:I596 RS04245
gene id: 1300342:I596_RS04245
uniprot id: A0A160DRV3
names: Similarity
messages: Belongs to the Skp family.

1300342:I596 RS14330
gene id: 1300342:I596_RS14330
uniprot id: A0A160DWN5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1300342:I596 RS03280
gene id: 1300342:I596_RS03280
uniprot id: A0A160DRV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1300342:I596 RS06140
gene id: 1300342:I596_RS06140
uniprot id: A0A160DSS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1300342:I596 RS02960
gene id: 1300342:I596_RS02960
uniprot id: A0A161HJB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1300342:I596 RS04240
gene id: 1300342:I596_RS04240
uniprot id: A0A160DSA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1300342:I596 RS10070
gene id: 1300342:I596_RS10070
uniprot id: A0A160DWC3
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1300342:I596 RS07220
gene id: 1300342:I596_RS07220
uniprot id: A0A160DTA3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1300342:I596 RS16605
gene id: 1300342:I596_RS16605
uniprot id: A0A160DY68
names: Similarity
messages: Belongs to the YkuD family.

1300342:I596 RS11080
gene id: 1300342:I596_RS11080
uniprot id: A0A160DV45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1300342:I596 RS12260
gene id: 1300342:I596_RS12260
uniprot id: A0A160DVP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1300342:I596 RS02695
gene id: 1300342:I596_RS02695
uniprot id: A0A167GJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1300342:I596 RS00180
gene id: 1300342:I596_RS00180
uniprot id: A0A167G2A8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1300342:I596 RS16210
gene id: 1300342:I596_RS16210
uniprot id: A0A160DXJ9
names: Similarity
messages: Belongs to the peptidase M1 family.

1300342:I596 RS00370
gene id: 1300342:I596_RS00370
uniprot id: A0A167G3K1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1300342:I596 RS08525
gene id: 1300342:I596_RS08525
uniprot id: A0A160DUT7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1300342:I596 RS03975
gene id: 1300342:I596_RS03975
uniprot id: A0A160DRQ3
names: Similarity
messages: Belongs to the rubredoxin family.

1300342:I596 RS15040
gene id: 1300342:I596_RS15040
uniprot id: A0A160DWY9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS09690
gene id: 1300342:I596_RS09690
uniprot id: A0A160DVG3
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS01250
gene id: 1300342:I596_RS01250
uniprot id: A0A167G9K0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1300342:I596 RS01485
gene id: 1300342:I596_RS01485
uniprot id: A0A167GAT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS01200
gene id: 1300342:I596_RS01200
uniprot id: A0A161HIP7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS11210
gene id: 1300342:I596_RS11210
uniprot id: A0A160DV71
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1300342:I596 RS06840
gene id: 1300342:I596_RS06840
uniprot id: A0A160DU07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1300342:I596 RS17705
gene id: 1300342:I596_RS17705
uniprot id: A0A167HBA9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1300342:I596 RS15285
gene id: 1300342:I596_RS15285
uniprot id: A0A160DX40
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

1300342:I596 RS05385
gene id: 1300342:I596_RS05385
uniprot id: A0A160DSF6
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS08865
gene id: 1300342:I596_RS08865
uniprot id: A0A160DV29
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS09335
gene id: 1300342:I596_RS09335
uniprot id: A0A160DUA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1300342:I596 RS15090
gene id: 1300342:I596_RS15090
uniprot id: A0A167H6S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1300342:I596 RS08400
gene id: 1300342:I596_RS08400
uniprot id: A0A160DUB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1300342:I596 RS14015
gene id: 1300342:I596_RS14015
uniprot id: A0A167H596
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1300342:I596 RS11065
gene id: 1300342:I596_RS11065
uniprot id: A0A167H0H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS13685
gene id: 1300342:I596_RS13685
uniprot id: A0A160DY31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1300342:I596 RS05240
gene id: 1300342:I596_RS05240
uniprot id: A0A167GQV7
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS05005
gene id: 1300342:I596_RS05005
uniprot id: A0A160DSM6
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1300342:I596 RS03205
gene id: 1300342:I596_RS03205
uniprot id: A0A167GMD8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1300342:I596 RS04715
gene id: 1300342:I596_RS04715
uniprot id: A0A160DSZ0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300342:I596 RS05450
gene id: 1300342:I596_RS05450
uniprot id: A0A160DTC7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1300342:I596 RS03495
gene id: 1300342:I596_RS03495
uniprot id: A0A160DRK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1300342:I596 RS10045
gene id: 1300342:I596_RS10045
uniprot id: A0A160DUK6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1300342:I596 RS01125
gene id: 1300342:I596_RS01125
uniprot id: A0A167G8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS12555
gene id: 1300342:I596_RS12555
uniprot id: A0A160DW85
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1300342:I596 RS01990
gene id: 1300342:I596_RS01990
uniprot id: A0A167GED8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1300342:I596 RS11945
gene id: 1300342:I596_RS11945
uniprot id: A0A160DVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1300342:I596 RS00020
gene id: 1300342:I596_RS00020
uniprot id: A0A170R0M4
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

1300342:I596 RS00140
gene id: 1300342:I596_RS00140
uniprot id: A0A167G221
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS00365
gene id: 1300342:I596_RS00365
uniprot id: A0A167G3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1300342:I596 RS03590
gene id: 1300342:I596_RS03590
uniprot id: A0A160DRL6
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1300342:I596 RS08860
gene id: 1300342:I596_RS08860
uniprot id: A0A160DUZ3
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS12675
gene id: 1300342:I596_RS12675
uniprot id: A0A160DVU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1300342:I596 RS12980
gene id: 1300342:I596_RS12980
uniprot id: A0A167H3Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1300342:I596 RS14875
gene id: 1300342:I596_RS14875
uniprot id: A0A160DYL6
names: Subcellular Location Annotation
messages: Cytoplasm

1300342:I596 RS11150
gene id: 1300342:I596_RS11150
uniprot id: A0A160DVK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1300342:I596 RS07030
gene id: 1300342:I596_RS07030
uniprot id: A0A160DT84
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1300342:I596 RS02820
gene id: 1300342:I596_RS02820
uniprot id: A0A167GJZ5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1300342:I596 RS08145
gene id: 1300342:I596_RS08145
uniprot id: A0A160DTS3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1300342:I596 RS12480
gene id: 1300342:I596_RS12480
uniprot id: A0A160DVS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1300342:I596 RS03660
gene id: 1300342:I596_RS03660
uniprot id: A0A160DTC2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1300342:I596 RS11205
gene id: 1300342:I596_RS11205
uniprot id: A0A160DV56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS08985
gene id: 1300342:I596_RS08985
uniprot id: A0A160DU42
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1300342:I596 RS03310
gene id: 1300342:I596_RS03310
uniprot id: A0A160DSA3
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS01115
gene id: 1300342:I596_RS01115
uniprot id: A0A167G8V5
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1300342:I596 RS14090
gene id: 1300342:I596_RS14090
uniprot id: A0A160DWJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS07125
gene id: 1300342:I596_RS07125
uniprot id: A0A160DTA0
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1300342:I596 RS06255
gene id: 1300342:I596_RS06255
uniprot id: A0A160DSU7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1300342:I596 RS09775
gene id: 1300342:I596_RS09775
uniprot id: A0A160DUG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1300342:I596 RS04570
gene id: 1300342:I596_RS04570
uniprot id: A0A160DTR8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300342:I596 RS08025
gene id: 1300342:I596_RS08025
uniprot id: A0A160DU53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

1300342:I596 RS03155
gene id: 1300342:I596_RS03155
uniprot id: A0A167GM24
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1300342:I596 RS02640
gene id: 1300342:I596_RS02640
uniprot id: A0A167GIV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1300342:I596 RS10830
gene id: 1300342:I596_RS10830
uniprot id: A0A160DUY9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300342:I596 RS07495
gene id: 1300342:I596_RS07495
uniprot id: A0A167GU59
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1300342:I596 RS12360
gene id: 1300342:I596_RS12360
uniprot id: A0A160DVQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1300342:I596 RS17865
gene id: 1300342:I596_RS17865
uniprot id: A0A167HC96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1300342:I596 RS04650
gene id: 1300342:I596_RS04650
uniprot id: A0A160DSG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1300342:I596 RS04235
gene id: 1300342:I596_RS04235
uniprot id: A0A160DTL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1300342:I596 RS08320
gene id: 1300342:I596_RS08320
uniprot id: A0A160DUQ7
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1300342:I596 RS08555
gene id: 1300342:I596_RS08555
uniprot id: A0A167GW41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1300342:I596 RS12285
gene id: 1300342:I596_RS12285
uniprot id: A0A160DW36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1300342:I596 RS11645
gene id: 1300342:I596_RS11645
uniprot id: A0A160DVD0
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1300342:I596 RS13775
gene id: 1300342:I596_RS13775
uniprot id: A0A160DXC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS01475
gene id: 1300342:I596_RS01475
uniprot id: A0A167GAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS02345
gene id: 1300342:I596_RS02345
uniprot id: A0A167GGW1
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS16290
gene id: 1300342:I596_RS16290
uniprot id: A0A167H8V1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1300342:I596 RS10625
gene id: 1300342:I596_RS10625
uniprot id: A0A160DUV5
names: Subunit
messages: Homodimer.

1300342:I596 RS10095
gene id: 1300342:I596_RS10095
uniprot id: A0A160DUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS02490
gene id: 1300342:I596_RS02490
uniprot id: A0A167GHT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS14355
gene id: 1300342:I596_RS14355
uniprot id: A0A167H5S7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1300342:I596 RS00285
gene id: 1300342:I596_RS00285
uniprot id: A0A161HIG1
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS13960
gene id: 1300342:I596_RS13960
uniprot id: A0A160DXB6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1300342:I596 RS16635
gene id: 1300342:I596_RS16635
uniprot id: A0A167H9A3
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS08950
gene id: 1300342:I596_RS08950
uniprot id: A0A160DV46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1300342:I596 RS11665
gene id: 1300342:I596_RS11665
uniprot id: A0A167H1J0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1300342:I596 RS04485
gene id: 1300342:I596_RS04485
uniprot id: A0A167GPN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1300342:I596 RS06160
gene id: 1300342:I596_RS06160
uniprot id: A0A160DTP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300342:I596 RS12225
gene id: 1300342:I596_RS12225
uniprot id: A0A167H2K2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1300342:I596 RS15095
gene id: 1300342:I596_RS15095
uniprot id: A0A160DX04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1300342:I596 RS11095
gene id: 1300342:I596_RS11095
uniprot id: A0A167H0J1
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS00460
gene id: 1300342:I596_RS00460
uniprot id: A0A167G448
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS17180
gene id: 1300342:I596_RS17180
uniprot id: A0A160DY20
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS16430
gene id: 1300342:I596_RS16430
uniprot id: A0A160DXP3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS17125
gene id: 1300342:I596_RS17125
uniprot id: A0A160DYP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1300342:I596 RS09950
gene id: 1300342:I596_RS09950
uniprot id: A0A160DWA7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1300342:I596 RS04410
gene id: 1300342:I596_RS04410
uniprot id: A0A160DRW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1300342:I596 RS11845
gene id: 1300342:I596_RS11845
uniprot id: A0A160DVG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1300342:I596 RS00490
gene id: 1300342:I596_RS00490
uniprot id: A0A167G4C0
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS14800
gene id: 1300342:I596_RS14800
uniprot id: A0A160DWU7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1300342:I596 RS14705
gene id: 1300342:I596_RS14705
uniprot id: A0A160DX88
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1300342:I596 RS05235
gene id: 1300342:I596_RS05235
uniprot id: A0A160DSD6
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS17280
gene id: 1300342:I596_RS17280
uniprot id: A0A160DYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1300342:I596 RS00045
gene id: 1300342:I596_RS00045
uniprot id: A0A170R0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS03520
gene id: 1300342:I596_RS03520
uniprot id: A0A160DT99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS11530
gene id: 1300342:I596_RS11530
uniprot id: A0A161HRF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1300342:I596 RS12245
gene id: 1300342:I596_RS12245
uniprot id: A0A167H2L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1300342:I596 RS05935
gene id: 1300342:I596_RS05935
uniprot id: A0A160DSR0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1300342:I596 RS08445
gene id: 1300342:I596_RS08445
uniprot id: A0A160DVM0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1300342:I596 RS12235
gene id: 1300342:I596_RS12235
uniprot id: A0A160DW27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1300342:I596 RS09485
gene id: 1300342:I596_RS09485
uniprot id: A0A160DUC2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS11595
gene id: 1300342:I596_RS11595
uniprot id: A0A167H1B1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1300342:I596 RS06530
gene id: 1300342:I596_RS06530
uniprot id: A0A160DSY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1300342:I596 RS16480
gene id: 1300342:I596_RS16480
uniprot id: A0A160DXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS09035
gene id: 1300342:I596_RS09035
uniprot id: A0A160DU51
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1300342:I596 RS04495
gene id: 1300342:I596_RS04495
uniprot id: A0A160DRY2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1300342:I596 RS10055
gene id: 1300342:I596_RS10055
uniprot id: A0A160DVH4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1300342:I596 RS16095
gene id: 1300342:I596_RS16095
uniprot id: A0A167H890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1300342:I596 RS05965
gene id: 1300342:I596_RS05965
uniprot id: A0A160DTM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1300342:I596 RS00450
gene id: 1300342:I596_RS00450
uniprot id: A0A167G400
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS13400
gene id: 1300342:I596_RS13400
uniprot id: A0A167H4D1
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS12870
gene id: 1300342:I596_RS12870
uniprot id: A0A160DVY7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS01580
gene id: 1300342:I596_RS01580
uniprot id: A0A167GBL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1300342:I596 RS08510
gene id: 1300342:I596_RS08510
uniprot id: A0A160DTX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300342:I596 RS06795
gene id: 1300342:I596_RS06795
uniprot id: A0A160DU17
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1300342:I596 RS05945
gene id: 1300342:I596_RS05945
uniprot id: A0A160DSP2
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1300342:I596 RS10090
gene id: 1300342:I596_RS10090
uniprot id: A0A160DUL4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS16150
gene id: 1300342:I596_RS16150
uniprot id: A0A160DXJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS07230
gene id: 1300342:I596_RS07230
uniprot id: A0A160DTB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS11305
gene id: 1300342:I596_RS11305
uniprot id: A0A160DV87
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1300342:I596 RS08690
gene id: 1300342:I596_RS08690
uniprot id: A0A160DVR1
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1300342:I596 RS14980
gene id: 1300342:I596_RS14980
uniprot id: A0A160DXD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS02665
gene id: 1300342:I596_RS02665
uniprot id: A0A161HJ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1300342:I596 RS03610
gene id: 1300342:I596_RS03610
uniprot id: A0A160DSF9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300342:I596 RS16830
gene id: 1300342:I596_RS16830
uniprot id: A0A160DXW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300342:I596 RS02330
gene id: 1300342:I596_RS02330
uniprot id: A0A167GGT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1300342:I596 RS08005
gene id: 1300342:I596_RS08005
uniprot id: A0A160DUK8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1300342:I596 RS02910
gene id: 1300342:I596_RS02910
uniprot id: A0A167GKH1
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS04660
gene id: 1300342:I596_RS04660
uniprot id: A0A161HJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1300342:I596 RS10135
gene id: 1300342:I596_RS10135
uniprot id: A0A167GYQ1
names: Subcellular Location Annotation
messages: Cytoplasm

1300342:I596 RS02320
gene id: 1300342:I596_RS02320
uniprot id: A0A167GGR9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1300342:I596 RS09245
gene id: 1300342:I596_RS09245
uniprot id: A0A160DUA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

1300342:I596 RS10160
gene id: 1300342:I596_RS10160
uniprot id: A0A160DVM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. AOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-acetyl-L-ornithine to produce N(2)-acetyl-L-citrulline. This is a step in an alternative arginine biosynthesis pathway.
messages: Cytoplasm
messages: Homotrimer.

1300342:I596 RS07770
gene id: 1300342:I596_RS07770
uniprot id: A0A160DVA9
names: Subcellular Location Annotation
messages: Cytoplasm

1300342:I596 RS12640
gene id: 1300342:I596_RS12640
uniprot id: A0A160DWT6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1300342:I596 RS02205
gene id: 1300342:I596_RS02205
uniprot id: A0A167GFZ1
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS11935
gene id: 1300342:I596_RS11935
uniprot id: A0A167H201
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1300342:I596 RS15350
gene id: 1300342:I596_RS15350
uniprot id: A0A160DX43
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS12965
gene id: 1300342:I596_RS12965
uniprot id: A0A160DW04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1300342:I596 RS04390
gene id: 1300342:I596_RS04390
uniprot id: A0A160DSC5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1300342:I596 RS04250
gene id: 1300342:I596_RS04250
uniprot id: A0A167GP67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1300342:I596 RS04035
gene id: 1300342:I596_RS04035
uniprot id: A0A160DRQ9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1300342:I596 RS16485
gene id: 1300342:I596_RS16485
uniprot id: A0A160DXP7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1300342:I596 RS05540
gene id: 1300342:I596_RS05540
uniprot id: A0A160DTE2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1300342:I596 RS09555
gene id: 1300342:I596_RS09555
uniprot id: A0A160DW44
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1300342:I596 RS09945
gene id: 1300342:I596_RS09945
uniprot id: A0A167GY80
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1300342:I596 RS09090
gene id: 1300342:I596_RS09090
uniprot id: A0A160DU73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1300342:I596 RS06380
gene id: 1300342:I596_RS06380
uniprot id: A0A167GSM1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1300342:I596 RS14440
gene id: 1300342:I596_RS14440
uniprot id: A0A160DXI9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1300342:I596 RS14950
gene id: 1300342:I596_RS14950
uniprot id: A0A160DWX6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1300342:I596 RS12445
gene id: 1300342:I596_RS12445
uniprot id: A0A160DWP8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1300342:I596 RS03210
gene id: 1300342:I596_RS03210
uniprot id: A0A161HJG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1300342:I596 RS04070
gene id: 1300342:I596_RS04070
uniprot id: A0A160DS74
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS07820
gene id: 1300342:I596_RS07820
uniprot id: A0A160DVB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1300342:I596 RS12270
gene id: 1300342:I596_RS12270
uniprot id: A0A160DWM3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1300342:I596 RS06445
gene id: 1300342:I596_RS06445
uniprot id: A0A160DTU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1300342:I596 RS15025
gene id: 1300342:I596_RS15025
uniprot id: A0A167H6N4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1300342:I596 RS01875
gene id: 1300342:I596_RS01875
uniprot id: A0A167GDF6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1300342:I596 RS06490
gene id: 1300342:I596_RS06490
uniprot id: A0A160DTV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1300342:I596 RS14275
gene id: 1300342:I596_RS14275
uniprot id: A0A167H5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1300342:I596 RS08070
gene id: 1300342:I596_RS08070
uniprot id: A0A160DU61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1300342:I596 RS17325
gene id: 1300342:I596_RS17325
uniprot id: A0A160DY35
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1300342:I596 RS03570
gene id: 1300342:I596_RS03570
uniprot id: A0A160DTA7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1300342:I596 RS10100
gene id: 1300342:I596_RS10100
uniprot id: A0A160DUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1300342:I596 RS09450
gene id: 1300342:I596_RS09450
uniprot id: A0A167GXJ0
names: Similarity
messages: Belongs to the AHA1 family.

1300342:I596 RS03730
gene id: 1300342:I596_RS03730
uniprot id: A0A160DRN0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1300342:I596 RS11695
gene id: 1300342:I596_RS11695
uniprot id: A0A160DVE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1300342:I596 RS12375
gene id: 1300342:I596_RS12375
uniprot id: A0A167H2S7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS15125
gene id: 1300342:I596_RS15125
uniprot id: A0A160DYN6
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1300342:I596 RS12335
gene id: 1300342:I596_RS12335
uniprot id: A0A160DW46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1300342:I596 RS11215
gene id: 1300342:I596_RS11215
uniprot id: A0A160DW20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1300342:I596 RS13865
gene id: 1300342:I596_RS13865
uniprot id: A0A160DX98
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1300342:I596 RS01170
gene id: 1300342:I596_RS01170
uniprot id: A0A167G939
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1300342:I596 RS15200
gene id: 1300342:I596_RS15200
uniprot id: A0A160DX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1300342:I596 RS07605
gene id: 1300342:I596_RS07605
uniprot id: A0A160DTI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS11085
gene id: 1300342:I596_RS11085
uniprot id: A0A160DVZ3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1300342:I596 RS19180
gene id: 1300342:I596_RS19180
uniprot id: A0A160DZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1300342:I596 RS15240
gene id: 1300342:I596_RS15240
uniprot id: A0A160DX25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1300342:I596 RS02420
gene id: 1300342:I596_RS02420
uniprot id: A0A167GHC9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1300342:I596 RS01835
gene id: 1300342:I596_RS01835
uniprot id: A0A167GD91
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1300342:I596 RS16305
gene id: 1300342:I596_RS16305
uniprot id: A0A160DXL4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1300342:I596 RS16295
gene id: 1300342:I596_RS16295
uniprot id: A0A160DXM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1300342:I596 RS14695
gene id: 1300342:I596_RS14695
uniprot id: A0A161HRN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1300342:I596 RS07615
gene id: 1300342:I596_RS07615
uniprot id: A0A167GUB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1300342:I596 RS16365
gene id: 1300342:I596_RS16365
uniprot id: A0A160DYK3
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1300342:I596 RS06130
gene id: 1300342:I596_RS06130
uniprot id: A0A160DST8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1300342:I596 RS00110
gene id: 1300342:I596_RS00110
uniprot id: A0A167G1W8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1300342:I596 RS16955
gene id: 1300342:I596_RS16955
uniprot id: A0A160DZI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS01865
gene id: 1300342:I596_RS01865
uniprot id: A0A161HIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1300342:I596 RS07475
gene id: 1300342:I596_RS07475
uniprot id: A0A167GU50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1300342:I596 RS16510
gene id: 1300342:I596_RS16510
uniprot id: A0A160DY50
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1300342:I596 RS12560
gene id: 1300342:I596_RS12560
uniprot id: A0A160DVS0
names: Similarity
messages: Belongs to the citrate synthase family.

1300342:I596 RS17830
gene id: 1300342:I596_RS17830
uniprot id: A0A167HC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1300342:I596 RS12215
gene id: 1300342:I596_RS12215
uniprot id: A0A160DWI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1300342:I596 RS12275
gene id: 1300342:I596_RS12275
uniprot id: A0A161HRH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1300342:I596 RS10635
gene id: 1300342:I596_RS10635
uniprot id: A0A160DUX8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1300342:I596 RS17515
gene id: 1300342:I596_RS17515
uniprot id: A0A160DY78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1300342:I596 RS12450
gene id: 1300342:I596_RS12450
uniprot id: A0A167H2V4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1300342:I596 RS13040
gene id: 1300342:I596_RS13040
uniprot id: A0A167H3T6
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1300342:I596 RS15870
gene id: 1300342:I596_RS15870
uniprot id: A0A160DXD9
names: Subunit
messages: Monomer.

1300342:I596 RS02660
gene id: 1300342:I596_RS02660
uniprot id: A0A167GIZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1300342:I596 RS04535
gene id: 1300342:I596_RS04535
uniprot id: A0A167GPR8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1300342:I596 RS14680
gene id: 1300342:I596_RS14680
uniprot id: A0A160DWT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1300342:I596 RS08500
gene id: 1300342:I596_RS08500
uniprot id: A0A160DTX3
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS08745
gene id: 1300342:I596_RS08745
uniprot id: A0A160DU13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS14735
gene id: 1300342:I596_RS14735
uniprot id: A0A160DXT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1300342:I596 RS06460
gene id: 1300342:I596_RS06460
uniprot id: A0A160DUN8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1300342:I596 RS17210
gene id: 1300342:I596_RS17210
uniprot id: A0A160DY21
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1300342:I596 RS17285
gene id: 1300342:I596_RS17285
uniprot id: A0A160DYW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1300342:I596 RS09515
gene id: 1300342:I596_RS09515
uniprot id: A0A160DUD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1300342:I596 RS14350
gene id: 1300342:I596_RS14350
uniprot id: A0A160DXL8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1300342:I596 RS02555
gene id: 1300342:I596_RS02555
uniprot id: A0A167GI86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1300342:I596 RS14515
gene id: 1300342:I596_RS14515
uniprot id: A0A167H5Z2
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS12345
gene id: 1300342:I596_RS12345
uniprot id: A0A167H2R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1300342:I596 RS04695
gene id: 1300342:I596_RS04695
uniprot id: A0A160DS36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1300342:I596 RS11780
gene id: 1300342:I596_RS11780
uniprot id: A0A160DVV3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1300342:I596 RS17490
gene id: 1300342:I596_RS17490
uniprot id: A0A160DZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1300342:I596 RS08710
gene id: 1300342:I596_RS08710
uniprot id: A0A160DU01
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1300342:I596 RS16770
gene id: 1300342:I596_RS16770
uniprot id: A0A160DXV0
names: Similarity
messages: Belongs to the pirin family.

1300342:I596 RS12135
gene id: 1300342:I596_RS12135
uniprot id: A0A160DW11
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1300342:I596 RS03385
gene id: 1300342:I596_RS03385
uniprot id: A0A160DRJ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300342:I596 RS16330
gene id: 1300342:I596_RS16330
uniprot id: A0A160DY23
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1300342:I596 RS13700
gene id: 1300342:I596_RS13700
uniprot id: A0A167H4S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

1300342:I596 RS07385
gene id: 1300342:I596_RS07385
uniprot id: A0A160DTS0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1300342:I596 RS08175
gene id: 1300342:I596_RS08175
uniprot id: A0A167GV63
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS12895
gene id: 1300342:I596_RS12895
uniprot id: A0A160DWE8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1300342:I596 RS09240
gene id: 1300342:I596_RS09240
uniprot id: A0A160DU82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1300342:I596 RS15710
gene id: 1300342:I596_RS15710
uniprot id: A0A160DY91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1300342:I596 RS07765
gene id: 1300342:I596_RS07765
uniprot id: A0A167GUJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1300342:I596 RS07585
gene id: 1300342:I596_RS07585
uniprot id: A0A160DTH2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1300342:I596 RS05660
gene id: 1300342:I596_RS05660
uniprot id: A0A160DTG7
names: Similarity
messages: Belongs to the HSP15 family.

1300342:I596 RS12325
gene id: 1300342:I596_RS12325
uniprot id: A0A167H2P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1300342:I596 RS08595
gene id: 1300342:I596_RS08595
uniprot id: A0A160DUF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1300342:I596 RS12330
gene id: 1300342:I596_RS12330
uniprot id: A0A160DXE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1300342:I596 RS07380
gene id: 1300342:I596_RS07380
uniprot id: A0A160DV38
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1300342:I596 RS13415
gene id: 1300342:I596_RS13415
uniprot id: A0A167H4D9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

1300342:I596 RS12605
gene id: 1300342:I596_RS12605
uniprot id: A0A160DW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1300342:I596 RS09225
gene id: 1300342:I596_RS09225
uniprot id: A0A167GX64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1300342:I596 RS02195
gene id: 1300342:I596_RS02195
uniprot id: A0A167GFX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1300342:I596 RS15490
gene id: 1300342:I596_RS15490
uniprot id: A0A160DX67
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1300342:I596 RS06205
gene id: 1300342:I596_RS06205
uniprot id: A0A160DST7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300342:I596 RS09425
gene id: 1300342:I596_RS09425
uniprot id: A0A160DUB6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1300342:I596 RS00215
gene id: 1300342:I596_RS00215
uniprot id: A0A167G2I1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1300342:I596 RS01525
gene id: 1300342:I596_RS01525
uniprot id: A0A167GB57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS00465
gene id: 1300342:I596_RS00465
uniprot id: A0A167G464
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1300342:I596 RS02065
gene id: 1300342:I596_RS02065
uniprot id: A0A167GEW9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1300342:I596 RS03130
gene id: 1300342:I596_RS03130
uniprot id: A0A167GLY2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1300342:I596 RS02675
gene id: 1300342:I596_RS02675
uniprot id: A0A167GJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1300342:I596 RS04585
gene id: 1300342:I596_RS04585
uniprot id: A0A167GPU5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1300342:I596 RS02340
gene id: 1300342:I596_RS02340
uniprot id: A0A167GGV8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1300342:I596 RS10685
gene id: 1300342:I596_RS10685
uniprot id: A0A160DUY4
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1300342:I596 RS06790
gene id: 1300342:I596_RS06790
uniprot id: A0A160DTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1300342:I596 RS07670
gene id: 1300342:I596_RS07670
uniprot id: A0A160DV92
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1300342:I596 RS17060
gene id: 1300342:I596_RS17060
uniprot id: A0A167H9V3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1300342:I596 RS02865
gene id: 1300342:I596_RS02865
uniprot id: A0A167GK72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1300342:I596 RS06180
gene id: 1300342:I596_RS06180
uniprot id: A0A160DT71
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1300342:I596 RS00990
gene id: 1300342:I596_RS00990
uniprot id: A0A167G810
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1300342:I596 RS11910
gene id: 1300342:I596_RS11910
uniprot id: A0A160DWF8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1300342:I596 RS07350
gene id: 1300342:I596_RS07350
uniprot id: A0A160DTD1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1300342:I596 RS11130
gene id: 1300342:I596_RS11130
uniprot id: A0A160DW01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1300342:I596 RS10530
gene id: 1300342:I596_RS10530
uniprot id: A0A160DUU2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1300342:I596 RS15085
gene id: 1300342:I596_RS15085
uniprot id: A0A160DWZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1300342:I596 RS14070
gene id: 1300342:I596_RS14070
uniprot id: A0A160DY87
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS00280
gene id: 1300342:I596_RS00280
uniprot id: A0A167G2Z5
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1300342:I596 RS07110
gene id: 1300342:I596_RS07110
uniprot id: A0A167GTM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300342:I596 RS01520
gene id: 1300342:I596_RS01520
uniprot id: A0A161HIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS01080
gene id: 1300342:I596_RS01080
uniprot id: A0A167G8K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1300342:I596 RS11925
gene id: 1300342:I596_RS11925
uniprot id: A0A160DVX7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS09180
gene id: 1300342:I596_RS09180
uniprot id: A0A160DU80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1300342:I596 RS12300
gene id: 1300342:I596_RS12300
uniprot id: A0A160DVN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1300342:I596 RS12145
gene id: 1300342:I596_RS12145
uniprot id: A0A167H2C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1300342:I596 RS01985
gene id: 1300342:I596_RS01985
uniprot id: A0A167GEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1300342:I596 RS00900
gene id: 1300342:I596_RS00900
uniprot id: A0A167G7C8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1300342:I596 RS02165
gene id: 1300342:I596_RS02165
uniprot id: A0A167GFN2
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS15835
gene id: 1300342:I596_RS15835
uniprot id: A0A160DXC8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1300342:I596 RS03885
gene id: 1300342:I596_RS03885
uniprot id: A0A160DSJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1300342:I596 RS00190
gene id: 1300342:I596_RS00190
uniprot id: A0A161HIF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1300342:I596 RS09055
gene id: 1300342:I596_RS09055
uniprot id: A0A161HR82
names: Similarity
messages: Belongs to the ArsC family.

1300342:I596 RS11270
gene id: 1300342:I596_RS11270
uniprot id: A0A161HRE4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1300342:I596 RS06470
gene id: 1300342:I596_RS06470
uniprot id: A0A160DSY8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1300342:I596 RS06290
gene id: 1300342:I596_RS06290
uniprot id: A0A160DSU9
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS14990
gene id: 1300342:I596_RS14990
uniprot id: A0A167H6M3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1300342:I596 RS07805
gene id: 1300342:I596_RS07805
uniprot id: A0A160DUG7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1300342:I596 RS06980
gene id: 1300342:I596_RS06980
uniprot id: A0A160DT75
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1300342:I596 RS00130
gene id: 1300342:I596_RS00130
uniprot id: A0A167G201
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1300342:I596 RS00590
gene id: 1300342:I596_RS00590
uniprot id: A0A167G4Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1300342:I596 RS14585
gene id: 1300342:I596_RS14585
uniprot id: A0A160DXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1300342:I596 RS07240
gene id: 1300342:I596_RS07240
uniprot id: A0A160DU89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1300342:I596 RS14175
gene id: 1300342:I596_RS14175
uniprot id: A0A160DWJ2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1300342:I596 RS17340
gene id: 1300342:I596_RS17340
uniprot id: A0A167HA75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1300342:I596 RS17360
gene id: 1300342:I596_RS17360
uniprot id: A0A160DY56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1300342:I596 RS15020
gene id: 1300342:I596_RS15020
uniprot id: A0A160DXX8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1300342:I596 RS17870
gene id: 1300342:I596_RS17870
uniprot id: A0A167HC99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1300342:I596 RS02690
gene id: 1300342:I596_RS02690
uniprot id: A0A167GJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1300342:I596 RS12635
gene id: 1300342:I596_RS12635
uniprot id: A0A160DWP9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1300342:I596 RS17845
gene id: 1300342:I596_RS17845
uniprot id: A0A167HC58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1300342:I596 RS01155
gene id: 1300342:I596_RS01155
uniprot id: A0A167G909
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1300342:I596 RS15400
gene id: 1300342:I596_RS15400
uniprot id: A0A160DX51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1300342:I596 RS11520
gene id: 1300342:I596_RS11520
uniprot id: A0A160DW69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1300342:I596 RS07440
gene id: 1300342:I596_RS07440
uniprot id: A0A160DTE9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1300342:I596 RS14825
gene id: 1300342:I596_RS14825
uniprot id: A0A160DXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1300342:I596 RS14775
gene id: 1300342:I596_RS14775
uniprot id: A0A160DWV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS01140
gene id: 1300342:I596_RS01140
uniprot id: A0A167G8Z9
names: Similarity
messages: Belongs to the UPF0276 family.

1300342:I596 RS08095
gene id: 1300342:I596_RS08095
uniprot id: A0A160DTR5
names: Similarity
messages: Belongs to the UPF0276 family.

1300342:I596 RS07260
gene id: 1300342:I596_RS07260
uniprot id: A0A160DTB7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1300342:I596 RS07680
gene id: 1300342:I596_RS07680
uniprot id: A0A160DTI8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1300342:I596 RS07655
gene id: 1300342:I596_RS07655
uniprot id: A0A160DUE1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS07930
gene id: 1300342:I596_RS07930
uniprot id: A0A160DTM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1300342:I596 RS17450
gene id: 1300342:I596_RS17450
uniprot id: A0A160DY59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1300342:I596 RS00340
gene id: 1300342:I596_RS00340
uniprot id: A0A167G3C9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS15255
gene id: 1300342:I596_RS15255
uniprot id: A0A167H705
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1300342:I596 RS07040
gene id: 1300342:I596_RS07040
uniprot id: A0A160DU59
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1300342:I596 RS11380
gene id: 1300342:I596_RS11380
uniprot id: A0A167H112
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1300342:I596 RS08730
gene id: 1300342:I596_RS08730
uniprot id: A0A167GWC5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1300342:I596 RS13030
gene id: 1300342:I596_RS13030
uniprot id: A0A160DXR9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1300342:I596 RS03480
gene id: 1300342:I596_RS03480
uniprot id: A0A160DRK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1300342:I596 RS13790
gene id: 1300342:I596_RS13790
uniprot id: A0A160DWU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1300342:I596 RS14095
gene id: 1300342:I596_RS14095
uniprot id: A0A160DWJ0
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS02545
gene id: 1300342:I596_RS02545
uniprot id: A0A167GI64
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS07575
gene id: 1300342:I596_RS07575
uniprot id: A0A167GU78
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1300342:I596 RS05340
gene id: 1300342:I596_RS05340
uniprot id: A0A161HJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1300342:I596 RS07715
gene id: 1300342:I596_RS07715
uniprot id: A0A167GUF8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1300342:I596 RS14045
gene id: 1300342:I596_RS14045
uniprot id: A0A160DWI6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1300342:I596 RS07755
gene id: 1300342:I596_RS07755
uniprot id: A0A160DUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1300342:I596 RS05505
gene id: 1300342:I596_RS05505
uniprot id: A0A160DU79
names: Caution
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS11160
gene id: 1300342:I596_RS11160
uniprot id: A0A160DV48
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1300342:I596 RS16980
gene id: 1300342:I596_RS16980
uniprot id: A0A160DXY8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

1300342:I596 RS09680
gene id: 1300342:I596_RS09680
uniprot id: A0A160DUH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS07010
gene id: 1300342:I596_RS07010
uniprot id: A0A160DT78
names: Similarity
messages: Belongs to the YciI family.

1300342:I596 RS07450
gene id: 1300342:I596_RS07450
uniprot id: A0A160DTE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1300342:I596 RS13810
gene id: 1300342:I596_RS13810
uniprot id: A0A160DWE4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1300342:I596 RS07610
gene id: 1300342:I596_RS07610
uniprot id: A0A160DUD7
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1300342:I596 RS05500
gene id: 1300342:I596_RS05500
uniprot id: A0A167GR59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300342:I596 RS02380
gene id: 1300342:I596_RS02380
uniprot id: A0A167GH36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1300342:I596 RS07835
gene id: 1300342:I596_RS07835
uniprot id: A0A167GUN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS04540
gene id: 1300342:I596_RS04540
uniprot id: A0A160DRZ2
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS12645
gene id: 1300342:I596_RS12645
uniprot id: A0A167H379
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1300342:I596 RS17290
gene id: 1300342:I596_RS17290
uniprot id: A0A167HA53
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1300342:I596 RS13025
gene id: 1300342:I596_RS13025
uniprot id: A0A161HRJ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1300342:I596 RS07915
gene id: 1300342:I596_RS07915
uniprot id: A0A167GUU7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1300342:I596 RS04085
gene id: 1300342:I596_RS04085
uniprot id: A0A160DRR5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1300342:I596 RS02965
gene id: 1300342:I596_RS02965
uniprot id: A0A167GKS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1300342:I596 RS02570
gene id: 1300342:I596_RS02570
uniprot id: A0A167GIA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1300342:I596 RS07600
gene id: 1300342:I596_RS07600
uniprot id: A0A160DTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1300342:I596 RS03815
gene id: 1300342:I596_RS03815
uniprot id: A0A160DRP1
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1300342:I596 RS14570
gene id: 1300342:I596_RS14570
uniprot id: A0A160DWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS02615
gene id: 1300342:I596_RS02615
uniprot id: A0A161HJ78
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1300342:I596 RS03335
gene id: 1300342:I596_RS03335
uniprot id: A0A160DRJ0
names: Similarity
messages: Belongs to the citrate synthase family.

1300342:I596 RS13605
gene id: 1300342:I596_RS13605
uniprot id: A0A160DW94
names: Similarity
messages: Belongs to the peptidase M17 family.

1300342:I596 RS08365
gene id: 1300342:I596_RS08365
uniprot id: A0A160DTV9
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS02760
gene id: 1300342:I596_RS02760
uniprot id: A0A161HJ89
names: Similarity
messages: Belongs to the thioredoxin family.

1300342:I596 RS15305
gene id: 1300342:I596_RS15305
uniprot id: A0A160DXJ2
names: Similarity
messages: Belongs to the barstar family.

1300342:I596 RS10585
gene id: 1300342:I596_RS10585
uniprot id: A0A160DUX0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1300342:I596 RS08055
gene id: 1300342:I596_RS08055
uniprot id: A0A160DUP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1300342:I596 RS12230
gene id: 1300342:I596_RS12230
uniprot id: A0A160DXC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1300342:I596 RS17525
gene id: 1300342:I596_RS17525
uniprot id: A0A160DYS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1300342:I596 RS17530
gene id: 1300342:I596_RS17530
uniprot id: A0A160DZU3
names: Similarity
messages: Belongs to the peptidase M16 family.

1300342:I596 RS17825
gene id: 1300342:I596_RS17825
uniprot id: A0A167HC32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS10020
gene id: 1300342:I596_RS10020
uniprot id: A0A167GYD1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1300342:I596 RS07120
gene id: 1300342:I596_RS07120
uniprot id: A0A160DT85
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1300342:I596 RS06215
gene id: 1300342:I596_RS06215
uniprot id: A0A160DTR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1300342:I596 RS07690
gene id: 1300342:I596_RS07690
uniprot id: A0A160DTI5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1300342:I596 RS03920
gene id: 1300342:I596_RS03920
uniprot id: A0A160DRP8
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS04065
gene id: 1300342:I596_RS04065
uniprot id: A0A160DTI2
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1300342:I596 RS04360
gene id: 1300342:I596_RS04360
uniprot id: A0A160DRW2
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1300342:I596 RS02455
gene id: 1300342:I596_RS02455
uniprot id: A0A167GHL7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300342:I596 RS17335
gene id: 1300342:I596_RS17335
uniprot id: A0A160DYX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1300342:I596 RS01775
gene id: 1300342:I596_RS01775
uniprot id: A0A167GCV5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS14120
gene id: 1300342:I596_RS14120
uniprot id: A0A160DY96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS00235
gene id: 1300342:I596_RS00235
uniprot id: A0A167G2M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1300342:I596 RS06715
gene id: 1300342:I596_RS06715
uniprot id: A0A160DTG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300342:I596 RS04840
gene id: 1300342:I596_RS04840
uniprot id: A0A167GQA1
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS01980
gene id: 1300342:I596_RS01980
uniprot id: A0A167GEA0
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS09520
gene id: 1300342:I596_RS09520
uniprot id: A0A167GXN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1300342:I596 RS01120
gene id: 1300342:I596_RS01120
uniprot id: A0A167G8W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1300342:I596 RS14790
gene id: 1300342:I596_RS14790
uniprot id: A0A160DYK9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1300342:I596 RS14270
gene id: 1300342:I596_RS14270
uniprot id: A0A160DWK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1300342:I596 RS11020
gene id: 1300342:I596_RS11020
uniprot id: A0A160DV20
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS09315
gene id: 1300342:I596_RS09315
uniprot id: A0A160DW07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS09110
gene id: 1300342:I596_RS09110
uniprot id: A0A160DVX6
names: Similarity
messages: Belongs to the TrpF family.

1300342:I596 RS07045
gene id: 1300342:I596_RS07045
uniprot id: A0A167GTG6
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1300342:I596 RS02300
gene id: 1300342:I596_RS02300
uniprot id: A0A167GGP6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1300342:I596 RS02680
gene id: 1300342:I596_RS02680
uniprot id: A0A167GJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1300342:I596 RS09320
gene id: 1300342:I596_RS09320
uniprot id: A0A160DUR7
names: Similarity
messages: Belongs to the peptidase S1B family.

1300342:I596 RS04050
gene id: 1300342:I596_RS04050
uniprot id: A0A160DSM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1300342:I596 RS04400
gene id: 1300342:I596_RS04400
uniprot id: A0A167GPI7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1300342:I596 RS11090
gene id: 1300342:I596_RS11090
uniprot id: A0A160DW21
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1300342:I596 RS09545
gene id: 1300342:I596_RS09545
uniprot id: A0A160DVD9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1300342:I596 RS13755
gene id: 1300342:I596_RS13755
uniprot id: A0A160DWD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS14905
gene id: 1300342:I596_RS14905
uniprot id: A0A160DWX9
names: Similarity
messages: Belongs to the GSP E family.

1300342:I596 RS06340
gene id: 1300342:I596_RS06340
uniprot id: A0A160DSV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1300342:I596 RS11775
gene id: 1300342:I596_RS11775
uniprot id: A0A160DX53
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1300342:I596 RS02125
gene id: 1300342:I596_RS02125
uniprot id: A0A167GFD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1300342:I596 RS02830
gene id: 1300342:I596_RS02830
uniprot id: A0A167GK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1300342:I596 RS12205
gene id: 1300342:I596_RS12205
uniprot id: A0A160DVM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1300342:I596 RS05375
gene id: 1300342:I596_RS05375
uniprot id: A0A160DU57
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1300342:I596 RS07730
gene id: 1300342:I596_RS07730
uniprot id: A0A160DTJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1300342:I596 RS02840
gene id: 1300342:I596_RS02840
uniprot id: A0A167GK31
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1300342:I596 RS08905
gene id: 1300342:I596_RS08905
uniprot id: A0A160DV03
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300342:I596 RS13630
gene id: 1300342:I596_RS13630
uniprot id: A0A160DXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1300342:I596 RS18385
gene id: 1300342:I596_RS18385
uniprot id: A0A160DSI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS03350
gene id: 1300342:I596_RS03350
uniprot id: A0A160DSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS14415
gene id: 1300342:I596_RS14415
uniprot id: A0A160DX41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1300342:I596 RS14285
gene id: 1300342:I596_RS14285
uniprot id: A0A160DWM2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS02220
gene id: 1300342:I596_RS02220
uniprot id: A0A167GG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1300342:I596 RS06560
gene id: 1300342:I596_RS06560
uniprot id: A0A160DUQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1300342:I596 RS01255
gene id: 1300342:I596_RS01255
uniprot id: A0A167G9K8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1300342:I596 RS15575
gene id: 1300342:I596_RS15575
uniprot id: A0A160DYV3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1300342:I596 RS09160
gene id: 1300342:I596_RS09160
uniprot id: A0A160DVY3
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1300342:I596 RS08115
gene id: 1300342:I596_RS08115
uniprot id: A0A160DVH0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300342:I596 RS02975
gene id: 1300342:I596_RS02975
uniprot id: A0A167GKV6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1300342:I596 RS17370
gene id: 1300342:I596_RS17370
uniprot id: A0A160DY45
names: Similarity
messages: Belongs to the GSP E family.

1300342:I596 RS08980
gene id: 1300342:I596_RS08980
uniprot id: A0A160DU50
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1300342:I596 RS10640
gene id: 1300342:I596_RS10640
uniprot id: A0A160DVS4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1300342:I596 RS10780
gene id: 1300342:I596_RS10780
uniprot id: A0A160DUY0
names: Similarity
messages: Belongs to the catalase family.

1300342:I596 RS10010
gene id: 1300342:I596_RS10010
uniprot id: A0A160DVG6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1300342:I596 RS06735
gene id: 1300342:I596_RS06735
uniprot id: A0A160DT23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS03265
gene id: 1300342:I596_RS03265
uniprot id: A0A160DS97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1300342:I596 RS04795
gene id: 1300342:I596_RS04795
uniprot id: A0A167GQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1300342:I596 RS17625
gene id: 1300342:I596_RS17625
uniprot id: A0A167HAW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS07785
gene id: 1300342:I596_RS07785
uniprot id: A0A167GUM2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1300342:I596 RS17685
gene id: 1300342:I596_RS17685
uniprot id: A0A167HB79
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS01500
gene id: 1300342:I596_RS01500
uniprot id: A0A167GAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS10885
gene id: 1300342:I596_RS10885
uniprot id: A0A160DVW3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1300342:I596 RS02630
gene id: 1300342:I596_RS02630
uniprot id: A0A167GIS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS14080
gene id: 1300342:I596_RS14080
uniprot id: A0A160DWH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1300342:I596 RS13765
gene id: 1300342:I596_RS13765
uniprot id: A0A160DWD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1300342:I596 RS09890
gene id: 1300342:I596_RS09890
uniprot id: A0A160DVJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Gfa family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.

1300342:I596 RS15010
gene id: 1300342:I596_RS15010
uniprot id: A0A160DWZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1300342:I596 RS03415
gene id: 1300342:I596_RS03415
uniprot id: A0A167GMX6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1300342:I596 RS15390
gene id: 1300342:I596_RS15390
uniprot id: A0A160DYR9
names: Similarity
messages: Belongs to the PhoH family.

1300342:I596 RS02575
gene id: 1300342:I596_RS02575
uniprot id: A0A167GIB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1300342:I596 RS02140
gene id: 1300342:I596_RS02140
uniprot id: A0A161HJ13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1300342:I596 RS14165
gene id: 1300342:I596_RS14165
uniprot id: A0A160DYA3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1300342:I596 RS09120
gene id: 1300342:I596_RS09120
uniprot id: A0A160DU77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1300342:I596 RS06235
gene id: 1300342:I596_RS06235
uniprot id: A0A160DT81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1300342:I596 RS09870
gene id: 1300342:I596_RS09870
uniprot id: A0A160DUI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1300342:I596 RS05060
gene id: 1300342:I596_RS05060
uniprot id: A0A160DSA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1300342:I596 RS01535
gene id: 1300342:I596_RS01535
uniprot id: A0A167GB78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS00325
gene id: 1300342:I596_RS00325
uniprot id: A0A167G3A5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1300342:I596 RS14365
gene id: 1300342:I596_RS14365
uniprot id: A0A160DX35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1300342:I596 RS11335
gene id: 1300342:I596_RS11335
uniprot id: A0A167H0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1300342:I596 RS03830
gene id: 1300342:I596_RS03830
uniprot id: A0A160DRN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1300342:I596 RS06750
gene id: 1300342:I596_RS06750
uniprot id: A0A167GSZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

1300342:I596 RS08085
gene id: 1300342:I596_RS08085
uniprot id: A0A160DTQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1300342:I596 RS02720
gene id: 1300342:I596_RS02720
uniprot id: A0A167GJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1300342:I596 RS13050
gene id: 1300342:I596_RS13050
uniprot id: A0A160DW22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1300342:I596 RS12940
gene id: 1300342:I596_RS12940
uniprot id: A0A160DXQ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300342:I596 RS11340
gene id: 1300342:I596_RS11340
uniprot id: A0A160DV81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1300342:I596 RS15635
gene id: 1300342:I596_RS15635
uniprot id: A0A167H7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1300342:I596 RS00605
gene id: 1300342:I596_RS00605
uniprot id: A0A167G519
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1300342:I596 RS00175
gene id: 1300342:I596_RS00175
uniprot id: A0A167G296
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1300342:I596 RS16010
gene id: 1300342:I596_RS16010
uniprot id: A0A160DXG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS05490
gene id: 1300342:I596_RS05490
uniprot id: A0A160DSG2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300342:I596 RS12500
gene id: 1300342:I596_RS12500
uniprot id: A0A160DXH0
names: Similarity
messages: Belongs to the WrbA family.

1300342:I596 RS10455
gene id: 1300342:I596_RS10455
uniprot id: A0A160DVP2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1300342:I596 RS07425
gene id: 1300342:I596_RS07425
uniprot id: A0A167GU39
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1300342:I596 RS08890
gene id: 1300342:I596_RS08890
uniprot id: A0A160DU36
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1300342:I596 RS16800
gene id: 1300342:I596_RS16800
uniprot id: A0A160DYP2
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS04275
gene id: 1300342:I596_RS04275
uniprot id: A0A160DSR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1300342:I596 RS07975
gene id: 1300342:I596_RS07975
uniprot id: A0A160DU43
names: Similarity
messages: Belongs to the peptidase U62 family.

1300342:I596 RS12430
gene id: 1300342:I596_RS12430
uniprot id: A0A160DVR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1300342:I596 RS16315
gene id: 1300342:I596_RS16315
uniprot id: A0A160DYJ7
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS12465
gene id: 1300342:I596_RS12465
uniprot id: A0A167H2W4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1300342:I596 RS10545
gene id: 1300342:I596_RS10545
uniprot id: A0A160DUU0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1300342:I596 RS04425
gene id: 1300342:I596_RS04425
uniprot id: A0A160DTP3
names: Similarity
messages: Belongs to the bacterioferritin family.

1300342:I596 RS09395
gene id: 1300342:I596_RS09395
uniprot id: A0A160DV76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1300342:I596 RS10415
gene id: 1300342:I596_RS10415
uniprot id: A0A167GZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1300342:I596 RS06150
gene id: 1300342:I596_RS06150
uniprot id: A0A160DSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300342:I596 RS18725
gene id: 1300342:I596_RS18725
uniprot id: A0A160DUT5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS02385
gene id: 1300342:I596_RS02385
uniprot id: A0A167GH43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1300342:I596 RS06940
gene id: 1300342:I596_RS06940
uniprot id: A0A160DU46
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1300342:I596 RS09560
gene id: 1300342:I596_RS09560
uniprot id: A0A160DUV7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1300342:I596 RS13000
gene id: 1300342:I596_RS13000
uniprot id: A0A167H3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1300342:I596 RS07885
gene id: 1300342:I596_RS07885
uniprot id: A0A167GUT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS01845
gene id: 1300342:I596_RS01845
uniprot id: A0A167GDA7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1300342:I596 RS02355
gene id: 1300342:I596_RS02355
uniprot id: A0A167GGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

1300342:I596 RS03835
gene id: 1300342:I596_RS03835
uniprot id: A0A160DRN7
names: Similarity
messages: Belongs to the GSP N family.

1300342:I596 RS15580
gene id: 1300342:I596_RS15580
uniprot id: A0A160DXN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1300342:I596 RS04080
gene id: 1300342:I596_RS04080
uniprot id: A0A167GNY5
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1300342:I596 RS01925
gene id: 1300342:I596_RS01925
uniprot id: A0A167GDV9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS02470
gene id: 1300342:I596_RS02470
uniprot id: A0A167GHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300342:I596 RS02375
gene id: 1300342:I596_RS02375
uniprot id: A0A161HJ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS02585
gene id: 1300342:I596_RS02585
uniprot id: A0A167GIE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1300342:I596 RS05045
gene id: 1300342:I596_RS05045
uniprot id: A0A167GQJ6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1300342:I596 RS12905
gene id: 1300342:I596_RS12905
uniprot id: A0A167H3L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS08875
gene id: 1300342:I596_RS08875
uniprot id: A0A160DUK2
names: Similarity
messages: Belongs to the elongation factor P family.

1300342:I596 RS15480
gene id: 1300342:I596_RS15480
uniprot id: A0A167H7B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1300342:I596 RS07940
gene id: 1300342:I596_RS07940
uniprot id: A0A160DTM5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1300342:I596 RS04920
gene id: 1300342:I596_RS04920
uniprot id: A0A160DS77
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1300342:I596 RS16960
gene id: 1300342:I596_RS16960
uniprot id: A0A160DYD1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1300342:I596 RS10615
gene id: 1300342:I596_RS10615
uniprot id: A0A160DUV8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1300342:I596 RS07830
gene id: 1300342:I596_RS07830
uniprot id: A0A160DTL2
names: Similarity
messages: Belongs to the BolA/IbaG family.

1300342:I596 RS06310
gene id: 1300342:I596_RS06310
uniprot id: A0A167GSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1300342:I596 RS09025
gene id: 1300342:I596_RS09025
uniprot id: A0A167GWW4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS17385
gene id: 1300342:I596_RS17385
uniprot id: A0A167HAB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1300342:I596 RS03775
gene id: 1300342:I596_RS03775
uniprot id: A0A167GNI9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1300342:I596 RS02580
gene id: 1300342:I596_RS02580
uniprot id: A0A167GIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1300342:I596 RS03475
gene id: 1300342:I596_RS03475
uniprot id: A0A160DRY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1300342:I596 RS02225
gene id: 1300342:I596_RS02225
uniprot id: A0A167GG35
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300342:I596 RS08685
gene id: 1300342:I596_RS08685
uniprot id: A0A167GWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS11240
gene id: 1300342:I596_RS11240
uniprot id: A0A160DV64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1300342:I596 RS07895
gene id: 1300342:I596_RS07895
uniprot id: A0A160DTL8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1300342:I596 RS04045
gene id: 1300342:I596_RS04045
uniprot id: A0A160DRQ5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1300342:I596 RS12140
gene id: 1300342:I596_RS12140
uniprot id: A0A160DVK9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1300342:I596 RS12610
gene id: 1300342:I596_RS12610
uniprot id: A0A160DVS8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS02280
gene id: 1300342:I596_RS02280
uniprot id: A0A167GGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1300342:I596 RS03825
gene id: 1300342:I596_RS03825
uniprot id: A0A160DRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1300342:I596 RS05610
gene id: 1300342:I596_RS05610
uniprot id: A0A160DSI5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1300342:I596 RS09330
gene id: 1300342:I596_RS09330
uniprot id: A0A167GX93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300342:I596 RS10850
gene id: 1300342:I596_RS10850
uniprot id: A0A167H010
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1300342:I596 RS04255
gene id: 1300342:I596_RS04255
uniprot id: A0A160DRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1300342:I596 RS12690
gene id: 1300342:I596_RS12690
uniprot id: A0A160DWQ8
names: Similarity
messages: Belongs to the PhoH family.

1300342:I596 RS09345
gene id: 1300342:I596_RS09345
uniprot id: A0A160DUB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1300342:I596 RS08050
gene id: 1300342:I596_RS08050
uniprot id: A0A160DUL5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1300342:I596 RS01165
gene id: 1300342:I596_RS01165
uniprot id: A0A167G930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1300342:I596 RS16875
gene id: 1300342:I596_RS16875
uniprot id: A0A160DXX2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS15055
gene id: 1300342:I596_RS15055
uniprot id: A0A160DX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS09715
gene id: 1300342:I596_RS09715
uniprot id: A0A167GXX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1300342:I596 RS12680
gene id: 1300342:I596_RS12680
uniprot id: A0A160DVV1
names: Subcellular Location Annotation
messages: Cytoplasm

1300342:I596 RS03340
gene id: 1300342:I596_RS03340
uniprot id: A0A160DRJ2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1300342:I596 RS11505
gene id: 1300342:I596_RS11505
uniprot id: A0A160DVA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS10035
gene id: 1300342:I596_RS10035
uniprot id: A0A160DUL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1300342:I596 RS03645
gene id: 1300342:I596_RS03645
uniprot id: A0A160DRL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1300342:I596 RS12320
gene id: 1300342:I596_RS12320
uniprot id: A0A160DWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1300342:I596 RS03080
gene id: 1300342:I596_RS03080
uniprot id: A0A167GLL0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300342:I596 RS07735
gene id: 1300342:I596_RS07735
uniprot id: A0A167GUG8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1300342:I596 RS02940
gene id: 1300342:I596_RS02940
uniprot id: A0A167GKN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS13845
gene id: 1300342:I596_RS13845
uniprot id: A0A167H4Z7
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1300342:I596 RS11660
gene id: 1300342:I596_RS11660
uniprot id: A0A160DWC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1300342:I596 RS03905
gene id: 1300342:I596_RS03905
uniprot id: A0A160DS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS10870
gene id: 1300342:I596_RS10870
uniprot id: A0A167H044
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1300342:I596 RS10060
gene id: 1300342:I596_RS10060
uniprot id: A0A160DVL8
names: Similarity
messages: Belongs to the histone deacetylase family.

1300342:I596 RS01150
gene id: 1300342:I596_RS01150
uniprot id: A0A161HIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1300342:I596 RS13470
gene id: 1300342:I596_RS13470
uniprot id: A0A160DW89
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1300342:I596 RS13950
gene id: 1300342:I596_RS13950
uniprot id: A0A160DWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1300342:I596 RS02685
gene id: 1300342:I596_RS02685
uniprot id: A0A167GJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1300342:I596 RS14995
gene id: 1300342:I596_RS14995
uniprot id: A0A160DWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1300342:I596 RS02560
gene id: 1300342:I596_RS02560
uniprot id: A0A167GI94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1300342:I596 RS08215
gene id: 1300342:I596_RS08215
uniprot id: A0A160DTS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS01495
gene id: 1300342:I596_RS01495
uniprot id: A0A167GAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS14605
gene id: 1300342:I596_RS14605
uniprot id: A0A160DX72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1300342:I596 RS04175
gene id: 1300342:I596_RS04175
uniprot id: A0A160DRS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300342:I596 RS07305
gene id: 1300342:I596_RS07305
uniprot id: A0A160DTC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1300342:I596 RS05415
gene id: 1300342:I596_RS05415
uniprot id: A0A160DU64
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1300342:I596 RS00100
gene id: 1300342:I596_RS00100
uniprot id: A0A167G1U5
names: Similarity
messages: Belongs to the pirin family.

1300342:I596 RS04450
gene id: 1300342:I596_RS04450
uniprot id: A0A160DRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1300342:I596 RS10855
gene id: 1300342:I596_RS10855
uniprot id: A0A160DWP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1300342:I596 RS14685
gene id: 1300342:I596_RS14685
uniprot id: A0A160DXM7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1300342:I596 RS03950
gene id: 1300342:I596_RS03950
uniprot id: A0A160DTG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1300342:I596 RS07020
gene id: 1300342:I596_RS07020
uniprot id: A0A160DT70
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300342:I596 RS07990
gene id: 1300342:I596_RS07990
uniprot id: A0A160DTN8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1300342:I596 RS15550
gene id: 1300342:I596_RS15550
uniprot id: A0A160DX82
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS04980
gene id: 1300342:I596_RS04980
uniprot id: A0A160DS68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1300342:I596 RS00350
gene id: 1300342:I596_RS00350
uniprot id: A0A167G3E4
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS07080
gene id: 1300342:I596_RS07080
uniprot id: A0A160DU45
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300342:I596 RS05545
gene id: 1300342:I596_RS05545
uniprot id: A0A167GR71
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS01995
gene id: 1300342:I596_RS01995
uniprot id: A0A167GEF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1300342:I596 RS07945
gene id: 1300342:I596_RS07945
uniprot id: A0A160DTM6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1300342:I596 RS01570
gene id: 1300342:I596_RS01570
uniprot id: A0A167GBI8
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS00355
gene id: 1300342:I596_RS00355
uniprot id: A0A167G3G4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1300342:I596 RS00255
gene id: 1300342:I596_RS00255
uniprot id: A0A167G2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1300342:I596 RS09875
gene id: 1300342:I596_RS09875
uniprot id: A0A160DUI2
names: Similarity
messages: Belongs to the glutamate synthase family.

1300342:I596 RS00570
gene id: 1300342:I596_RS00570
uniprot id: A0A167G4T9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1300342:I596 RS09705
gene id: 1300342:I596_RS09705
uniprot id: A0A160DUX9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1300342:I596 RS04260
gene id: 1300342:I596_RS04260
uniprot id: A0A160DRU5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS13035
gene id: 1300342:I596_RS13035
uniprot id: A0A160DW03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1300342:I596 RS16300
gene id: 1300342:I596_RS16300
uniprot id: A0A160DXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1300342:I596 RS07470
gene id: 1300342:I596_RS07470
uniprot id: A0A160DUD6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1300342:I596 RS15195
gene id: 1300342:I596_RS15195
uniprot id: A0A160DX20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1300342:I596 RS06200
gene id: 1300342:I596_RS06200
uniprot id: A0A160DSS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300342:I596 RS14485
gene id: 1300342:I596_RS14485
uniprot id: A0A160DWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1300342:I596 RS06665
gene id: 1300342:I596_RS06665
uniprot id: A0A160DTF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1300342:I596 RS11700
gene id: 1300342:I596_RS11700
uniprot id: A0A160DVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS00250
gene id: 1300342:I596_RS00250
uniprot id: A0A167G2P2
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS17070
gene id: 1300342:I596_RS17070
uniprot id: A0A160DY06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1300342:I596 RS03450
gene id: 1300342:I596_RS03450
uniprot id: A0A160DRK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1300342:I596 RS09305
gene id: 1300342:I596_RS09305
uniprot id: A0A160DVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1300342:I596 RS12210
gene id: 1300342:I596_RS12210
uniprot id: A0A160DVN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1300342:I596 RS03320
gene id: 1300342:I596_RS03320
uniprot id: A0A160DRV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1300342:I596 RS02550
gene id: 1300342:I596_RS02550
uniprot id: A0A167GI75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1300342:I596 RS04740
gene id: 1300342:I596_RS04740
uniprot id: A0A160DS43
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1300342:I596 RS17575
gene id: 1300342:I596_RS17575
uniprot id: A0A167HAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1300342:I596 RS00595
gene id: 1300342:I596_RS00595
uniprot id: A0A167G504
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1300342:I596 RS10105
gene id: 1300342:I596_RS10105
uniprot id: A0A160DVI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1300342:I596 RS08540
gene id: 1300342:I596_RS08540
uniprot id: A0A160DVN7
names: Similarity
messages: Belongs to the YciI family.

1300342:I596 RS10860
gene id: 1300342:I596_RS10860
uniprot id: A0A160DVG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1300342:I596 RS10795
gene id: 1300342:I596_RS10795
uniprot id: A0A160DVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1300342:I596 RS06450
gene id: 1300342:I596_RS06450
uniprot id: A0A160DTV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1300342:I596 RS12530
gene id: 1300342:I596_RS12530
uniprot id: A0A160DVT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1300342:I596 RS10140
gene id: 1300342:I596_RS10140
uniprot id: A0A160DUM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily.
messages: Binds 1 Co(2+) ion per subunit.
messages: Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline. This is a step in an alternative arginine biosynthesis pathway.

1300342:I596 RS05985
gene id: 1300342:I596_RS05985
uniprot id: A0A161HJP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1300342:I596 RS12425
gene id: 1300342:I596_RS12425
uniprot id: A0A160DVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1300342:I596 RS17405
gene id: 1300342:I596_RS17405
uniprot id: A0A167HAB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1300342:I596 RS13745
gene id: 1300342:I596_RS13745
uniprot id: A0A160DWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1300342:I596 RS01445
gene id: 1300342:I596_RS01445
uniprot id: A0A167GAL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1300342:I596 RS02295
gene id: 1300342:I596_RS02295
uniprot id: A0A167GGM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1300342:I596 RS07405
gene id: 1300342:I596_RS07405
uniprot id: A0A160DTD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS07325
gene id: 1300342:I596_RS07325
uniprot id: A0A167GTZ1
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS02905
gene id: 1300342:I596_RS02905
uniprot id: A0A167GKG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS03015
gene id: 1300342:I596_RS03015
uniprot id: A0A167GL30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1300342:I596 RS01270
gene id: 1300342:I596_RS01270
uniprot id: A0A167G9M4
names: Similarity
messages: Belongs to the UPF0502 family.

1300342:I596 RS01855
gene id: 1300342:I596_RS01855
uniprot id: A0A167GDC5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1300342:I596 RS05135
gene id: 1300342:I596_RS05135
uniprot id: A0A160DT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS15610
gene id: 1300342:I596_RS15610
uniprot id: A0A160DY79
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1300342:I596 RS02015
gene id: 1300342:I596_RS02015
uniprot id: A0A161HIZ1
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1300342:I596 RS04185
gene id: 1300342:I596_RS04185
uniprot id: A0A160DSP9
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS14520
gene id: 1300342:I596_RS14520
uniprot id: A0A160DWR2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1300342:I596 RS07455
gene id: 1300342:I596_RS07455
uniprot id: A0A160DTE3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1300342:I596 RS03285
gene id: 1300342:I596_RS03285
uniprot id: A0A160DRI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1300342:I596 RS03425
gene id: 1300342:I596_RS03425
uniprot id: A0A160DRX2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300342:I596 RS07345
gene id: 1300342:I596_RS07345
uniprot id: A0A167GTZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS14655
gene id: 1300342:I596_RS14655
uniprot id: A0A160DX80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1300342:I596 RS06375
gene id: 1300342:I596_RS06375
uniprot id: A0A160DSX7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1300342:I596 RS11175
gene id: 1300342:I596_RS11175
uniprot id: A0A160DW10
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1300342:I596 RS07950
gene id: 1300342:I596_RS07950
uniprot id: A0A160DTN5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1300342:I596 RS03635
gene id: 1300342:I596_RS03635
uniprot id: A0A167GNB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1300342:I596 RS15670
gene id: 1300342:I596_RS15670
uniprot id: A0A160DYV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300342:I596 RS06825
gene id: 1300342:I596_RS06825
uniprot id: A0A160DT35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300342:I596 RS00305
gene id: 1300342:I596_RS00305
uniprot id: A0A167G343
names: Similarity
messages: Belongs to the GSP E family.

1300342:I596 RS01315
gene id: 1300342:I596_RS01315
uniprot id: A0A167G9U3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS11915
gene id: 1300342:I596_RS11915
uniprot id: A0A167H1Y6
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS17460
gene id: 1300342:I596_RS17460
uniprot id: A0A160DY75
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1300342:I596 RS06210
gene id: 1300342:I596_RS06210
uniprot id: A0A160DTQ3
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS16250
gene id: 1300342:I596_RS16250
uniprot id: A0A160DXK8
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS04580
gene id: 1300342:I596_RS04580
uniprot id: A0A160DS09
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS17175
gene id: 1300342:I596_RS17175
uniprot id: A0A167HA01
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1300342:I596 RS04140
gene id: 1300342:I596_RS04140
uniprot id: A0A160DSN6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300342:I596 RS12290
gene id: 1300342:I596_RS12290
uniprot id: A0A160DVN0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1300342:I596 RS08495
gene id: 1300342:I596_RS08495
uniprot id: A0A160DUD2
names: Similarity
messages: Belongs to the peptidase S13 family.

1300342:I596 RS04290
gene id: 1300342:I596_RS04290
uniprot id: A0A160DSB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1300342:I596 RS14155
gene id: 1300342:I596_RS14155
uniprot id: A0A160DXI6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1300342:I596 RS03500
gene id: 1300342:I596_RS03500
uniprot id: A0A160DRK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS17215
gene id: 1300342:I596_RS17215
uniprot id: A0A167HA26
names: Similarity
messages: Belongs to the glutamine synthetase family.

1300342:I596 RS10660
gene id: 1300342:I596_RS10660
uniprot id: A0A160DVC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1300342:I596 RS07695
gene id: 1300342:I596_RS07695
uniprot id: A0A160DTI4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1300342:I596 RS03195
gene id: 1300342:I596_RS03195
uniprot id: A0A167GMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1300342:I596 RS08065
gene id: 1300342:I596_RS08065
uniprot id: A0A160DVG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS02880
gene id: 1300342:I596_RS02880
uniprot id: A0A167GKA5
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1300342:I596 RS14295
gene id: 1300342:I596_RS14295
uniprot id: A0A160DXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1300342:I596 RS06265
gene id: 1300342:I596_RS06265
uniprot id: A0A160DTS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1300342:I596 RS17875
gene id: 1300342:I596_RS17875
uniprot id: A0A167HCA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1300342:I596 RS05650
gene id: 1300342:I596_RS05650
uniprot id: A0A160DSH9
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS14635
gene id: 1300342:I596_RS14635
uniprot id: A0A160DXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1300342:I596 RS11620
gene id: 1300342:I596_RS11620
uniprot id: A0A160DWB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1300342:I596 RS05510
gene id: 1300342:I596_RS05510
uniprot id: A0A160DSV4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1300342:I596 RS05055
gene id: 1300342:I596_RS05055
uniprot id: A0A160DSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1300342:I596 RS12805
gene id: 1300342:I596_RS12805
uniprot id: A0A160DVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1300342:I596 RS12280
gene id: 1300342:I596_RS12280
uniprot id: A0A160DXD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1300342:I596 RS11525
gene id: 1300342:I596_RS11525
uniprot id: A0A160DW99
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS05400
gene id: 1300342:I596_RS05400
uniprot id: A0A160DSE5
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1300342:I596 RS15375
gene id: 1300342:I596_RS15375
uniprot id: A0A160DXZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS08305
gene id: 1300342:I596_RS08305
uniprot id: A0A160DTT8
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS09185
gene id: 1300342:I596_RS09185
uniprot id: A0A160DU75
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1300342:I596 RS14265
gene id: 1300342:I596_RS14265
uniprot id: A0A160DX19
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS02160
gene id: 1300342:I596_RS02160
uniprot id: A0A167GFM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1300342:I596 RS04285
gene id: 1300342:I596_RS04285
uniprot id: A0A160DTM2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS09730
gene id: 1300342:I596_RS09730
uniprot id: A0A160DUI1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1300342:I596 RS03060
gene id: 1300342:I596_RS03060
uniprot id: A0A167GLH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

1300342:I596 RS02725
gene id: 1300342:I596_RS02725
uniprot id: A0A167GJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1300342:I596 RS02705
gene id: 1300342:I596_RS02705
uniprot id: A0A167GJ66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1300342:I596 RS02055
gene id: 1300342:I596_RS02055
uniprot id: A0A167GEU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1300342:I596 RS02670
gene id: 1300342:I596_RS02670
uniprot id: A0A167GJ01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1300342:I596 RS10705
gene id: 1300342:I596_RS10705
uniprot id: A0A167GZT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1300342:I596 RS10680
gene id: 1300342:I596_RS10680
uniprot id: A0A160DUW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1300342:I596 RS14795
gene id: 1300342:I596_RS14795
uniprot id: A0A160DXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1300342:I596 RS03960
gene id: 1300342:I596_RS03960
uniprot id: A0A160DRQ7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1300342:I596 RS10725
gene id: 1300342:I596_RS10725
uniprot id: A0A167GZU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1300342:I596 RS16375
gene id: 1300342:I596_RS16375
uniprot id: A0A160DZ73
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1300342:I596 RS08230
gene id: 1300342:I596_RS08230
uniprot id: A0A167GVI3
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS03260
gene id: 1300342:I596_RS03260
uniprot id: A0A161HJG5
names: Similarity
messages: Belongs to the YggT family.

1300342:I596 RS12960
gene id: 1300342:I596_RS12960
uniprot id: A0A160DW06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1300342:I596 RS11930
gene id: 1300342:I596_RS11930
uniprot id: A0A160DVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1300342:I596 RS16035
gene id: 1300342:I596_RS16035
uniprot id: A0A160DXX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1300342:I596 RS12485
gene id: 1300342:I596_RS12485
uniprot id: A0A160DWM4
names: Similarity
messages: Belongs to the acylphosphatase family.

1300342:I596 RS06700
gene id: 1300342:I596_RS06700
uniprot id: A0A160DU00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

1300342:I596 RS02755
gene id: 1300342:I596_RS02755
uniprot id: A0A167GJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1300342:I596 RS15595
gene id: 1300342:I596_RS15595
uniprot id: A0A160DX95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1300342:I596 RS09600
gene id: 1300342:I596_RS09600
uniprot id: A0A160DW53
names: Similarity
messages: Belongs to the peptidase M13 family.

1300342:I596 RS16015
gene id: 1300342:I596_RS16015
uniprot id: A0A160DXG6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1300342:I596 RS17235
gene id: 1300342:I596_RS17235
uniprot id: A0A160DYQ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS03025
gene id: 1300342:I596_RS03025
uniprot id: A0A167GL69
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1300342:I596 RS09965
gene id: 1300342:I596_RS09965
uniprot id: A0A167GYB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1300342:I596 RS10955
gene id: 1300342:I596_RS10955
uniprot id: A0A160DVH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1300342:I596 RS06645
gene id: 1300342:I596_RS06645
uniprot id: A0A160DTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1300342:I596 RS00565
gene id: 1300342:I596_RS00565
uniprot id: A0A167G4S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1300342:I596 RS10440
gene id: 1300342:I596_RS10440
uniprot id: A0A160DUS3
names: Similarity
messages: Belongs to the universal stress protein A family.

1300342:I596 RS07900
gene id: 1300342:I596_RS07900
uniprot id: A0A160DTM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300342:I596 RS08000
gene id: 1300342:I596_RS08000
uniprot id: A0A160DTP9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1300342:I596 RS01300
gene id: 1300342:I596_RS01300
uniprot id: A0A167G9S7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1300342:I596 RS06295
gene id: 1300342:I596_RS06295
uniprot id: A0A160DSU6
names: Similarity
messages: Belongs to the UPF0178 family.

1300342:I596 RS17155
gene id: 1300342:I596_RS17155
uniprot id: A0A160DYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1300342:I596 RS04265
gene id: 1300342:I596_RS04265
uniprot id: A0A160DRU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1300342:I596 RS12935
gene id: 1300342:I596_RS12935
uniprot id: A0A167H3M3
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS14495
gene id: 1300342:I596_RS14495
uniprot id: A0A167H5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1300342:I596 RS01030
gene id: 1300342:I596_RS01030
uniprot id: A0A167G8A3
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1300342:I596 RS12800
gene id: 1300342:I596_RS12800
uniprot id: A0A160DWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1300342:I596 RS16125
gene id: 1300342:I596_RS16125
uniprot id: A0A167H8A6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1300342:I596 RS07675
gene id: 1300342:I596_RS07675
uniprot id: A0A160DTY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1300342:I596 RS13710
gene id: 1300342:I596_RS13710
uniprot id: A0A160DWC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1300342:I596 RS04505
gene id: 1300342:I596_RS04505
uniprot id: A0A160DSV2
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1300342:I596 RS09135
gene id: 1300342:I596_RS09135
uniprot id: A0A160DU65
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1300342:I596 RS12515
gene id: 1300342:I596_RS12515
uniprot id: A0A167H2Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1300342:I596 RS06650
gene id: 1300342:I596_RS06650
uniprot id: A0A160DTZ2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1300342:I596 RS09170
gene id: 1300342:I596_RS09170
uniprot id: A0A160DU81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1300342:I596 RS15015
gene id: 1300342:I596_RS15015
uniprot id: A0A160DXS9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1300342:I596 RS07905
gene id: 1300342:I596_RS07905
uniprot id: A0A160DUI4
names: Similarity
messages: Belongs to the universal stress protein A family.

1300342:I596 RS01470
gene id: 1300342:I596_RS01470
uniprot id: A0A167GAQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS04215
gene id: 1300342:I596_RS04215
uniprot id: A0A160DRT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1300342:I596 RS01490
gene id: 1300342:I596_RS01490
uniprot id: A0A167GAV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS06300
gene id: 1300342:I596_RS06300
uniprot id: A0A160DTR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1300342:I596 RS10710
gene id: 1300342:I596_RS10710
uniprot id: A0A160DWM1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1300342:I596 RS13425
gene id: 1300342:I596_RS13425
uniprot id: A0A160DW82
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1300342:I596 RS07620
gene id: 1300342:I596_RS07620
uniprot id: A0A160DV84
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1300342:I596 RS08990
gene id: 1300342:I596_RS08990
uniprot id: A0A160DU60
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1300342:I596 RS03970
gene id: 1300342:I596_RS03970
uniprot id: A0A160DRQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1300342:I596 RS11200
gene id: 1300342:I596_RS11200
uniprot id: A0A167H0P2
names: Similarity
messages: Belongs to the peptidase S49 family.

1300342:I596 RS11675
gene id: 1300342:I596_RS11675
uniprot id: A0A160DVT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1300342:I596 RS06545
gene id: 1300342:I596_RS06545
uniprot id: A0A160DTW0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1300342:I596 RS00600
gene id: 1300342:I596_RS00600
uniprot id: A0A167G512
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1300342:I596 RS15930
gene id: 1300342:I596_RS15930
uniprot id: A0A160DYD2
names: Similarity
messages: Belongs to the Gfa family.

1300342:I596 RS11585
gene id: 1300342:I596_RS11585
uniprot id: A0A160DVS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1300342:I596 RS08125
gene id: 1300342:I596_RS08125
uniprot id: A0A160DTR4
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1300342:I596 RS03925
gene id: 1300342:I596_RS03925
uniprot id: A0A160DRP9
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS14430
gene id: 1300342:I596_RS14430
uniprot id: A0A160DWQ0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300342:I596 RS08580
gene id: 1300342:I596_RS08580
uniprot id: A0A160DUY6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1300342:I596 RS17545
gene id: 1300342:I596_RS17545
uniprot id: A0A167HAJ4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1300342:I596 RS14135
gene id: 1300342:I596_RS14135
uniprot id: A0A167H5H5
names: Similarity
messages: Belongs to the PrpD family.

1300342:I596 RS00840
gene id: 1300342:I596_RS00840
uniprot id: A0A167G6T9
names: Similarity
messages: Belongs to the P(II) protein family.

1300342:I596 RS10645
gene id: 1300342:I596_RS10645
uniprot id: A0A160DVV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1300342:I596 RS09040
gene id: 1300342:I596_RS09040
uniprot id: A0A160DU66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1300342:I596 RS14715
gene id: 1300342:I596_RS14715
uniprot id: A0A160DWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1300342:I596 RS11255
gene id: 1300342:I596_RS11255
uniprot id: A0A160DV79
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1300342:I596 RS03895
gene id: 1300342:I596_RS03895
uniprot id: A0A167GNS2
names: Similarity
messages: Belongs to the universal stress protein A family.

1300342:I596 RS01160
gene id: 1300342:I596_RS01160
uniprot id: A0A167G915
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1300342:I596 RS01900
gene id: 1300342:I596_RS01900
uniprot id: A0A167GDQ7
names: Similarity
messages: Belongs to the GARS family.

1300342:I596 RS02275
gene id: 1300342:I596_RS02275
uniprot id: A0A161HJ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1300342:I596 RS01035
gene id: 1300342:I596_RS01035
uniprot id: A0A167G8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1300342:I596 RS00890
gene id: 1300342:I596_RS00890
uniprot id: A0A167G7A4
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1300342:I596 RS02565
gene id: 1300342:I596_RS02565
uniprot id: A0A161HJ69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS14710
gene id: 1300342:I596_RS14710
uniprot id: A0A160DWT0
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1300342:I596 RS07130
gene id: 1300342:I596_RS07130
uniprot id: A0A160DU52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300342:I596 RS02590
gene id: 1300342:I596_RS02590
uniprot id: A0A167GIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1300342:I596 RS17595
gene id: 1300342:I596_RS17595
uniprot id: A0A167HAQ9
names: Similarity
messages: Belongs to the UPF0234 family.

1300342:I596 RS06595
gene id: 1300342:I596_RS06595
uniprot id: A0A160DTW9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1300342:I596 RS01860
gene id: 1300342:I596_RS01860
uniprot id: A0A167GDE4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1300342:I596 RS06535
gene id: 1300342:I596_RS06535
uniprot id: A0A160DSY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1300342:I596 RS03900
gene id: 1300342:I596_RS03900
uniprot id: A0A160DTF8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1300342:I596 RS12770
gene id: 1300342:I596_RS12770
uniprot id: A0A160DVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS11220
gene id: 1300342:I596_RS11220
uniprot id: A0A160DW48
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1300342:I596 RS07430
gene id: 1300342:I596_RS07430
uniprot id: A0A160DV49
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1300342:I596 RS08455
gene id: 1300342:I596_RS08455
uniprot id: A0A160DTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1300342:I596 RS11330
gene id: 1300342:I596_RS11330
uniprot id: A0A160DV80
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1300342:I596 RS12725
gene id: 1300342:I596_RS12725
uniprot id: A0A160DVV8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1300342:I596 RS09380
gene id: 1300342:I596_RS09380
uniprot id: A0A160DUA8
names: Similarity
messages: Belongs to the pirin family.

1300342:I596 RS11235
gene id: 1300342:I596_RS11235
uniprot id: A0A160DVL9
names: Similarity
messages: Belongs to the threonine synthase family.

1300342:I596 RS14505
gene id: 1300342:I596_RS14505
uniprot id: A0A160DX57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS14110
gene id: 1300342:I596_RS14110
uniprot id: A0A160DXH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1300342:I596 RS09960
gene id: 1300342:I596_RS09960
uniprot id: A0A160DUK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1300342:I596 RS04785
gene id: 1300342:I596_RS04785
uniprot id: A0A160DSJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1300342:I596 RS00495
gene id: 1300342:I596_RS00495
uniprot id: A0A167G4C6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300342:I596 RS14525
gene id: 1300342:I596_RS14525
uniprot id: A0A160DWR1
names: Similarity
messages: Belongs to the Dps family.

1300342:I596 RS15940
gene id: 1300342:I596_RS15940
uniprot id: A0A160DYZ3
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS07340
gene id: 1300342:I596_RS07340
uniprot id: A0A160DTD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1300342:I596 RS08845
gene id: 1300342:I596_RS08845
uniprot id: A0A160DU29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1300342:I596 RS00670
gene id: 1300342:I596_RS00670
uniprot id: A0A167G5M3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1300342:I596 RS11920
gene id: 1300342:I596_RS11920
uniprot id: A0A160DX78
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1300342:I596 RS17890
gene id: 1300342:I596_RS17890
uniprot id: A0A167HCC4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS00480
gene id: 1300342:I596_RS00480
uniprot id: A0A161HIH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1300342:I596 RS12295
gene id: 1300342:I596_RS12295
uniprot id: A0A167H2N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1300342:I596 RS12650
gene id: 1300342:I596_RS12650
uniprot id: A0A160DXJ5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1300342:I596 RS13455
gene id: 1300342:I596_RS13455
uniprot id: A0A160DWN4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300342:I596 RS13740
gene id: 1300342:I596_RS13740
uniprot id: A0A160DWT5
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1300342:I596 RS12420
gene id: 1300342:I596_RS12420
uniprot id: A0A160DVQ5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1300342:I596 RS17365
gene id: 1300342:I596_RS17365
uniprot id: A0A160DY54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1300342:I596 RS04820
gene id: 1300342:I596_RS04820
uniprot id: A0A167GQ92
names: Similarity
messages: Belongs to the PhzF family.

1300342:I596 RS06165
gene id: 1300342:I596_RS06165
uniprot id: A0A160DTQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300342:I596 RS14675
gene id: 1300342:I596_RS14675
uniprot id: A0A160DWT2
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1300342:I596 RS07660
gene id: 1300342:I596_RS07660
uniprot id: A0A160DUG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1300342:I596 RS04025
gene id: 1300342:I596_RS04025
uniprot id: A0A160DS63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS01480
gene id: 1300342:I596_RS01480
uniprot id: A0A161HIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1300342:I596 RS15995
gene id: 1300342:I596_RS15995
uniprot id: A0A160DXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1300342:I596 RS03290
gene id: 1300342:I596_RS03290
uniprot id: A0A167GMQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1300342:I596 RS13885
gene id: 1300342:I596_RS13885
uniprot id: A0A160DWV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1300342:I596 RS00650
gene id: 1300342:I596_RS00650
uniprot id: A0A167G5E9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300342:I596 RS16285
gene id: 1300342:I596_RS16285
uniprot id: A0A160DXL0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS17165
gene id: 1300342:I596_RS17165
uniprot id: A0A160DZM0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1300342:I596 RS09150
gene id: 1300342:I596_RS09150
uniprot id: A0A160DV78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1300342:I596 RS16490
gene id: 1300342:I596_RS16490
uniprot id: A0A160DXP4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1300342:I596 RS07410
gene id: 1300342:I596_RS07410
uniprot id: A0A160DTE8
names: Similarity
messages: Belongs to the HesB/IscA family.

1300342:I596 RS06660
gene id: 1300342:I596_RS06660
uniprot id: A0A160DUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1300342:I596 RS14935
gene id: 1300342:I596_RS14935
uniprot id: A0A160DWX1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS00165
gene id: 1300342:I596_RS00165
uniprot id: A0A167G263
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1300342:I596 RS02405
gene id: 1300342:I596_RS02405
uniprot id: A0A167GHA2
names: Similarity
messages: Belongs to the UPF0145 family.

1300342:I596 RS00295
gene id: 1300342:I596_RS00295
uniprot id: A0A167G318
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1300342:I596 RS07165
gene id: 1300342:I596_RS07165
uniprot id: A0A160DT96
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS06185
gene id: 1300342:I596_RS06185
uniprot id: A0A160DSU5
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

1300342:I596 RS15960
gene id: 1300342:I596_RS15960
uniprot id: A0A160DXG2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1300342:I596 RS08505
gene id: 1300342:I596_RS08505
uniprot id: A0A167GVW4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS17200
gene id: 1300342:I596_RS17200
uniprot id: A0A160DZN0
names: Similarity
messages: Belongs to the peptidase S8 family.

1300342:I596 RS14785
gene id: 1300342:I596_RS14785
uniprot id: A0A167H6B0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1300342:I596 RS06105
gene id: 1300342:I596_RS06105
uniprot id: A0A160DTP2
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1300342:I596 RS15070
gene id: 1300342:I596_RS15070
uniprot id: A0A167H6R4
names: Subcellular Location Annotation
messages: Cytoplasm

1300342:I596 RS06610
gene id: 1300342:I596_RS06610
uniprot id: A0A160DUR2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1300342:I596 RS13020
gene id: 1300342:I596_RS13020
uniprot id: A0A160DX10
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1300342:I596 RS06095
gene id: 1300342:I596_RS06095
uniprot id: A0A160DSS0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1300342:I596 RS17245
gene id: 1300342:I596_RS17245
uniprot id: A0A161HRW7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300342:I596 RS05960
gene id: 1300342:I596_RS05960
uniprot id: A0A160DTL5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1300342:I596 RS14340
gene id: 1300342:I596_RS14340
uniprot id: A0A160DWM9
names: Subcellular Location Annotation
messages: Membrane

1300342:I596 RS11855
gene id: 1300342:I596_RS11855
uniprot id: A0A160DWC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1300342:I596 RS12615
gene id: 1300342:I596_RS12615
uniprot id: A0A167H369
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300342:I596 RS09250
gene id: 1300342:I596_RS09250
uniprot id: A0A160DV52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1300342:I596 RS03470
gene id: 1300342:I596_RS03470
uniprot id: A0A160DT91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1300342:I596 RS00055
gene id: 1300342:I596_RS00055
uniprot id: A0A170R0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1300342:I596 RS08450
gene id: 1300342:I596_RS08450
uniprot id: A0A160DUC7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1300342:I596 RS10565
gene id: 1300342:I596_RS10565
uniprot id: A0A160DWJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300342:I596 RS08830
gene id: 1300342:I596_RS08830
uniprot id: A0A160DUJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1300342:I596 RS15555
gene id: 1300342:I596_RS15555
uniprot id: A0A160DX92
names: Similarity
messages: Belongs to the peptidase M16 family.

1300342:I596 RS09740
gene id: 1300342:I596_RS09740
uniprot id: A0A160DVH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1300342:I596 RS12185
gene id: 1300342:I596_RS12185
uniprot id: A0A160DW18
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1300342:I596 RS01850
gene id: 1300342:I596_RS01850
uniprot id: A0A167GDB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1300342:I596 RS05190
gene id: 1300342:I596_RS05190
uniprot id: A0A160DSC4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1300342:I596 RS05390
gene id: 1300342:I596_RS05390
uniprot id: A0A167GR11
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300342:I596 RS07275
gene id: 1300342:I596_RS07275
uniprot id: A0A160DTA9
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.