1298851:AXH83 RS09000
gene id: 1298851:AXH83_RS09000
uniprot id: A0A0S3QVZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1298851:AXH83 RS03570
gene id: 1298851:AXH83_RS03570
uniprot id: A0A0S3QT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1298851:AXH83 RS04675
gene id: 1298851:AXH83_RS04675
uniprot id: A0A0S3QTR8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1298851:AXH83 RS05010
gene id: 1298851:AXH83_RS05010
uniprot id: A0A0S3QTV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1298851:AXH83 RS03005
gene id: 1298851:AXH83_RS03005
uniprot id: A0A0S3QST4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1298851:AXH83 RS04235
gene id: 1298851:AXH83_RS04235
uniprot id: A0A0S3QTG2
names: Similarity
messages: Belongs to the universal stress protein A family.

1298851:AXH83 RS03145
gene id: 1298851:AXH83_RS03145
uniprot id: A0A0S3QSW4
names: Similarity
messages: Belongs to the thioredoxin family.

1298851:AXH83 RS02700
gene id: 1298851:AXH83_RS02700
uniprot id: A0A0S3QSM4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1298851:AXH83 RS07985
gene id: 1298851:AXH83_RS07985
uniprot id: A0A0S3QVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS04925
gene id: 1298851:AXH83_RS04925
uniprot id: A0A0S3QTT2
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS05385
gene id: 1298851:AXH83_RS05385
uniprot id: A0A0S3QU28
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1298851:AXH83 RS03665
gene id: 1298851:AXH83_RS03665
uniprot id: A0A0S3QT46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1298851:AXH83 RS03735
gene id: 1298851:AXH83_RS03735
uniprot id: A0A0S3QT67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1298851:AXH83 RS05530
gene id: 1298851:AXH83_RS05530
uniprot id: A0A0S3QU51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1298851:AXH83 RS01030
gene id: 1298851:AXH83_RS01030
uniprot id: A0A0S3QRP6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1298851:AXH83 RS05750
gene id: 1298851:AXH83_RS05750
uniprot id: A0A0S3QU89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1298851:AXH83 RS08925
gene id: 1298851:AXH83_RS08925
uniprot id: A0A0S3QVW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS07005
gene id: 1298851:AXH83_RS07005
uniprot id: A0A0S3QUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1298851:AXH83 RS06375
gene id: 1298851:AXH83_RS06375
uniprot id: A0A0S3QUN2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1298851:AXH83 RS08680
gene id: 1298851:AXH83_RS08680
uniprot id: A0A0S3QVT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1298851:AXH83 RS06660
gene id: 1298851:AXH83_RS06660
uniprot id: A0A0S3QUS6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1298851:AXH83 RS08265
gene id: 1298851:AXH83_RS08265
uniprot id: A0A0S3QVK5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS02815
gene id: 1298851:AXH83_RS02815
uniprot id: A0A0S3QSQ2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1298851:AXH83 RS05885
gene id: 1298851:AXH83_RS05885
uniprot id: A0A0S3QUC6
names: Similarity
messages: Belongs to the histone deacetylase family.

1298851:AXH83 RS05965
gene id: 1298851:AXH83_RS05965
uniprot id: A0A0S3QUD5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1298851:AXH83 RS01810
gene id: 1298851:AXH83_RS01810
uniprot id: A0A0S3QS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1298851:AXH83 RS08045
gene id: 1298851:AXH83_RS08045
uniprot id: A0A0S3QVE9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1298851:AXH83 RS05995
gene id: 1298851:AXH83_RS05995
uniprot id: A0A0S3QUF2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1298851:AXH83 RS05470
gene id: 1298851:AXH83_RS05470
uniprot id: A0A0S3QU53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS07385
gene id: 1298851:AXH83_RS07385
uniprot id: A0A0S3QV45
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1298851:AXH83 RS06300
gene id: 1298851:AXH83_RS06300
uniprot id: A0A0S3QUK4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1298851:AXH83 RS01855
gene id: 1298851:AXH83_RS01855
uniprot id: A0A0S3QS52
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1298851:AXH83 RS08505
gene id: 1298851:AXH83_RS08505
uniprot id: A0A0S3QVP5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS00005
gene id: 1298851:AXH83_RS00005
uniprot id: A0A0S3QR56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1298851:AXH83 RS06010
gene id: 1298851:AXH83_RS06010
uniprot id: A0A0S3QUD4
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1298851:AXH83 RS02705
gene id: 1298851:AXH83_RS02705
uniprot id: A0A0S3QSL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1298851:AXH83 RS02690
gene id: 1298851:AXH83_RS02690
uniprot id: A0A0S3QSQ1
names: Similarity
messages: Belongs to the CinA family.

1298851:AXH83 RS04015
gene id: 1298851:AXH83_RS04015
uniprot id: A0A0S3QTB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1298851:AXH83 RS07055
gene id: 1298851:AXH83_RS07055
uniprot id: A0A0S3QUX3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1298851:AXH83 RS06665
gene id: 1298851:AXH83_RS06665
uniprot id: A0A0S3QUR5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS03000
gene id: 1298851:AXH83_RS03000
uniprot id: A0A0S3QST7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1298851:AXH83 RS08035
gene id: 1298851:AXH83_RS08035
uniprot id: A0A0S3QVE4
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1298851:AXH83 RS05485
gene id: 1298851:AXH83_RS05485
uniprot id: A0A0S3QU50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1298851:AXH83 RS03130
gene id: 1298851:AXH83_RS03130
uniprot id: A0A0S3QST9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1298851:AXH83 RS06120
gene id: 1298851:AXH83_RS06120
uniprot id: A0A0S3QUF1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1298851:AXH83 RS01530
gene id: 1298851:AXH83_RS01530
uniprot id: A0A0S3QS01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1298851:AXH83 RS07095
gene id: 1298851:AXH83_RS07095
uniprot id: A0A0S3QUY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS06960
gene id: 1298851:AXH83_RS06960
uniprot id: A0A0S3QUX8
names: Similarity
messages: Belongs to the fabD family.

1298851:AXH83 RS06145
gene id: 1298851:AXH83_RS06145
uniprot id: A0A0S3QUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS01660
gene id: 1298851:AXH83_RS01660
uniprot id: A0A0S3QS51
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS08205
gene id: 1298851:AXH83_RS08205
uniprot id: A0A0S3QVI7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1298851:AXH83 RS01450
gene id: 1298851:AXH83_RS01450
uniprot id: A0A0S3QRY5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1298851:AXH83 RS01785
gene id: 1298851:AXH83_RS01785
uniprot id: A0A0S3QS64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1298851:AXH83 RS00045
gene id: 1298851:AXH83_RS00045
uniprot id: A0A0S3QR43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS04585
gene id: 1298851:AXH83_RS04585
uniprot id: A0A0S3QTM3
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1298851:AXH83 RS02800
gene id: 1298851:AXH83_RS02800
uniprot id: A0A0S3QSU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1298851:AXH83 RS09810
gene id: 1298851:AXH83_RS09810
uniprot id: A0A0S3QT06
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1298851:AXH83 RS09065
gene id: 1298851:AXH83_RS09065
uniprot id: A0A0S3QVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1298851:AXH83 RS03660
gene id: 1298851:AXH83_RS03660
uniprot id: A0A0S3QT56
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS00020
gene id: 1298851:AXH83_RS00020
uniprot id: A0A0S3QR50
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1298851:AXH83 RS05545
gene id: 1298851:AXH83_RS05545
uniprot id: A0A0S3QU73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1298851:AXH83 RS02310
gene id: 1298851:AXH83_RS02310
uniprot id: A0A0S3QSH7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1298851:AXH83 RS07475
gene id: 1298851:AXH83_RS07475
uniprot id: A0A0S3QV85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1298851:AXH83 RS06380
gene id: 1298851:AXH83_RS06380
uniprot id: A0A0S3QUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1298851:AXH83 RS05465
gene id: 1298851:AXH83_RS05465
uniprot id: A0A0S3QU49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1298851:AXH83 RS08795
gene id: 1298851:AXH83_RS08795
uniprot id: A0A0S3QVX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1298851:AXH83 RS06975
gene id: 1298851:AXH83_RS06975
uniprot id: A0A0S3QUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1298851:AXH83 RS00535
gene id: 1298851:AXH83_RS00535
uniprot id: A0A0S3QRL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1298851:AXH83 RS04610
gene id: 1298851:AXH83_RS04610
uniprot id: A0A0S3QTM5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the N-terminal section; belongs to the MobA family.

1298851:AXH83 RS08305
gene id: 1298851:AXH83_RS08305
uniprot id: A0A0S3QVK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1298851:AXH83 RS05350
gene id: 1298851:AXH83_RS05350
uniprot id: A0A0S3QU44
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1298851:AXH83 RS01915
gene id: 1298851:AXH83_RS01915
uniprot id: A0A0S3QS66
names: Similarity
messages: Belongs to the GSP E family.

1298851:AXH83 RS02820
gene id: 1298851:AXH83_RS02820
uniprot id: A0A0S3QSQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1298851:AXH83 RS09070
gene id: 1298851:AXH83_RS09070
uniprot id: A0A0S3QW09
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1298851:AXH83 RS04525
gene id: 1298851:AXH83_RS04525
uniprot id: A0A0S3QTL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1298851:AXH83 RS05910
gene id: 1298851:AXH83_RS05910
uniprot id: A0A0S3QUD2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1298851:AXH83 RS01965
gene id: 1298851:AXH83_RS01965
uniprot id: A0A0S3QSA3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1298851:AXH83 RS06400
gene id: 1298851:AXH83_RS06400
uniprot id: A0A0S3QUL7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1298851:AXH83 RS06510
gene id: 1298851:AXH83_RS06510
uniprot id: A0A0S3QUM6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1298851:AXH83 RS01390
gene id: 1298851:AXH83_RS01390
uniprot id: A0A0S3QRY9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS07925
gene id: 1298851:AXH83_RS07925
uniprot id: A0A0S3QVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

1298851:AXH83 RS05035
gene id: 1298851:AXH83_RS05035
uniprot id: A0A0S3QTY0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1298851:AXH83 RS08630
gene id: 1298851:AXH83_RS08630
uniprot id: A0A0S3QVT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1298851:AXH83 RS00315
gene id: 1298851:AXH83_RS00315
uniprot id: A0A0S3QRA3
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS05615
gene id: 1298851:AXH83_RS05615
uniprot id: A0A0S3QU78
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.

1298851:AXH83 RS04825
gene id: 1298851:AXH83_RS04825
uniprot id: A0A0S3QTR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1298851:AXH83 RS01960
gene id: 1298851:AXH83_RS01960
uniprot id: A0A0S3QS84
names: Subcellular Location Annotation
messages: Mitochondrion

1298851:AXH83 RS04105
gene id: 1298851:AXH83_RS04105
uniprot id: A0A0S3QTC6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1298851:AXH83 RS06390
gene id: 1298851:AXH83_RS06390
uniprot id: A0A0S3QUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1298851:AXH83 RS08415
gene id: 1298851:AXH83_RS08415
uniprot id: A0A0S3QVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS04745
gene id: 1298851:AXH83_RS04745
uniprot id: A0A0S3QTQ1
names: Similarity
messages: Belongs to the histone deacetylase family.

1298851:AXH83 RS02640
gene id: 1298851:AXH83_RS02640
uniprot id: A0A0S3QSM2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1298851:AXH83 RS07125
gene id: 1298851:AXH83_RS07125
uniprot id: A0A0S3QUZ6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1298851:AXH83 RS00015
gene id: 1298851:AXH83_RS00015
uniprot id: A0A0S3QR51
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1298851:AXH83 RS02495
gene id: 1298851:AXH83_RS02495
uniprot id: A0A0S3QSJ8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS00930
gene id: 1298851:AXH83_RS00930
uniprot id: A0A0S3QRU4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1298851:AXH83 RS09840
gene id: 1298851:AXH83_RS09840
uniprot id: A0A0S3QUC1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1298851:AXH83 RS02730
gene id: 1298851:AXH83_RS02730
uniprot id: A0A0S3QSN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1298851:AXH83 RS04245
gene id: 1298851:AXH83_RS04245
uniprot id: A0A0S3QTI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS01715
gene id: 1298851:AXH83_RS01715
uniprot id: A0A0S3QS48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

1298851:AXH83 RS02855
gene id: 1298851:AXH83_RS02855
uniprot id: A0A0S3QSS8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1298851:AXH83 RS09060
gene id: 1298851:AXH83_RS09060
uniprot id: A0A0S3QW05
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1298851:AXH83 RS07590
gene id: 1298851:AXH83_RS07590
uniprot id: A0A0S3QV92
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1298851:AXH83 RS01360
gene id: 1298851:AXH83_RS01360
uniprot id: A0A0S3QRW2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1298851:AXH83 RS07560
gene id: 1298851:AXH83_RS07560
uniprot id: A0A0S3QV75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1298851:AXH83 RS06555
gene id: 1298851:AXH83_RS06555
uniprot id: A0A0S3QUR3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1298851:AXH83 RS05330
gene id: 1298851:AXH83_RS05330
uniprot id: A0A0S3QTZ8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1298851:AXH83 RS00960
gene id: 1298851:AXH83_RS00960
uniprot id: A0A0S3QRN9
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS07410
gene id: 1298851:AXH83_RS07410
uniprot id: A0A0S3QV37
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1298851:AXH83 RS04670
gene id: 1298851:AXH83_RS04670
uniprot id: A0A0S3QTN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1298851:AXH83 RS08070
gene id: 1298851:AXH83_RS08070
uniprot id: A0A0S3QVH9
names: Similarity
messages: Belongs to the peptidase S49 family.

1298851:AXH83 RS03110
gene id: 1298851:AXH83_RS03110
uniprot id: A0A0S3QSW8
names: Similarity
messages: Belongs to the FlgM family.

1298851:AXH83 RS02245
gene id: 1298851:AXH83_RS02245
uniprot id: A0A0S3QSC3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1298851:AXH83 RS01795
gene id: 1298851:AXH83_RS01795
uniprot id: A0A0S3QS80
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1298851:AXH83 RS00805
gene id: 1298851:AXH83_RS00805
uniprot id: A0A0S3QRK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1298851:AXH83 RS00030
gene id: 1298851:AXH83_RS00030
uniprot id: A0A0S3QRA0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1298851:AXH83 RS07520
gene id: 1298851:AXH83_RS07520
uniprot id: A0A0S3QV81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1298851:AXH83 RS00525
gene id: 1298851:AXH83_RS00525
uniprot id: A0A0S3QRF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1298851:AXH83 RS02930
gene id: 1298851:AXH83_RS02930
uniprot id: A0A0S3QSQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1298851:AXH83 RS02145
gene id: 1298851:AXH83_RS02145
uniprot id: A0A0S3QSF0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1298851:AXH83 RS07420
gene id: 1298851:AXH83_RS07420
uniprot id: A0A0S3QV31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1298851:AXH83 RS07485
gene id: 1298851:AXH83_RS07485
uniprot id: A0A0S3QV59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1298851:AXH83 RS07845
gene id: 1298851:AXH83_RS07845
uniprot id: A0A0S3QVB2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS05460
gene id: 1298851:AXH83_RS05460
uniprot id: A0A0S3QU43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS09220
gene id: 1298851:AXH83_RS09220
uniprot id: A0A0S3QW36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1298851:AXH83 RS07915
gene id: 1298851:AXH83_RS07915
uniprot id: A0A0S3QVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS08895
gene id: 1298851:AXH83_RS08895
uniprot id: A0A0S3QVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1298851:AXH83 RS01730
gene id: 1298851:AXH83_RS01730
uniprot id: A0A0S3QS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1298851:AXH83 RS09655
gene id: 1298851:AXH83_RS09655
uniprot id: A0A0S3QSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1298851:AXH83 RS04010
gene id: 1298851:AXH83_RS04010
uniprot id: A0A0S3QTD2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1298851:AXH83 RS03305
gene id: 1298851:AXH83_RS03305
uniprot id: A0A0S3QSX8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1298851:AXH83 RS05835
gene id: 1298851:AXH83_RS05835
uniprot id: A0A0S3QUA0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1298851:AXH83 RS07110
gene id: 1298851:AXH83_RS07110
uniprot id: A0A0S3QUZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1298851:AXH83 RS00505
gene id: 1298851:AXH83_RS00505
uniprot id: A0A0S3QRE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1298851:AXH83 RS08835
gene id: 1298851:AXH83_RS08835
uniprot id: A0A0S3QVV6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1298851:AXH83 RS03580
gene id: 1298851:AXH83_RS03580
uniprot id: A0A0S3QT31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1298851:AXH83 RS02325
gene id: 1298851:AXH83_RS02325
uniprot id: A0A0S3QSE8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1298851:AXH83 RS02790
gene id: 1298851:AXH83_RS02790
uniprot id: A0A0S3QSN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1298851:AXH83 RS03200
gene id: 1298851:AXH83_RS03200
uniprot id: A0A0S3QSY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1298851:AXH83 RS02305
gene id: 1298851:AXH83_RS02305
uniprot id: A0A0S3QSD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1298851:AXH83 RS02760
gene id: 1298851:AXH83_RS02760
uniprot id: A0A0S3QSN3
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS02785
gene id: 1298851:AXH83_RS02785
uniprot id: A0A0S3QSN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS04185
gene id: 1298851:AXH83_RS04185
uniprot id: A0A0S3QTE6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1298851:AXH83 RS02960
gene id: 1298851:AXH83_RS02960
uniprot id: A0A0S3QSX5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1298851:AXH83 RS00380
gene id: 1298851:AXH83_RS00380
uniprot id: A0A0S3QRD1
names: Similarity
messages: Belongs to the YicC/YloC family.

1298851:AXH83 RS01415
gene id: 1298851:AXH83_RS01415
uniprot id: A0A0S3QRX5
names: Similarity
messages: Belongs to the UPF0047 family.

1298851:AXH83 RS08125
gene id: 1298851:AXH83_RS08125
uniprot id: A0A0S3QVH6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1298851:AXH83 RS07960
gene id: 1298851:AXH83_RS07960
uniprot id: A0A0S3QVD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS04250
gene id: 1298851:AXH83_RS04250
uniprot id: A0A0S3QTF1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1298851:AXH83 RS08425
gene id: 1298851:AXH83_RS08425
uniprot id: A0A0S3QVN9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1298851:AXH83 RS04100
gene id: 1298851:AXH83_RS04100
uniprot id: A0A0S3QTD0
names: Function
names: Similarity
messages: Belongs to the citrate synthase family.
messages: Catalyzes both citrate generation and citrate cleavage. Part of a reversible tricarboxylic acid (TCA) cycle that can fix carbon dioxide autotrophically and may represent an ancestral mode of the conventional reductive TCA (rTCA) cycle. The direction is controlled by the available carbon source(s).

1298851:AXH83 RS02055
gene id: 1298851:AXH83_RS02055
uniprot id: A0A0S3QS85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1298851:AXH83 RS04290
gene id: 1298851:AXH83_RS04290
uniprot id: A0A0S3QTI2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1298851:AXH83 RS01440
gene id: 1298851:AXH83_RS01440
uniprot id: A0A0S3QRY1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1298851:AXH83 RS00870
gene id: 1298851:AXH83_RS00870
uniprot id: A0A0S3QRN5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1298851:AXH83 RS08710
gene id: 1298851:AXH83_RS08710
uniprot id: A0A0S3QVT3
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS05450
gene id: 1298851:AXH83_RS05450
uniprot id: A0A0S3QU36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1298851:AXH83 RS07940
gene id: 1298851:AXH83_RS07940
uniprot id: A0A0S3QVE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS06050
gene id: 1298851:AXH83_RS06050
uniprot id: A0A0S3QUG5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS05480
gene id: 1298851:AXH83_RS05480
uniprot id: A0A0S3QU46
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS07935
gene id: 1298851:AXH83_RS07935
uniprot id: A0A0S3QVE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS03160
gene id: 1298851:AXH83_RS03160
uniprot id: A0A0S3QSV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS06110
gene id: 1298851:AXH83_RS06110
uniprot id: A0A0S3QUF3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1298851:AXH83 RS04795
gene id: 1298851:AXH83_RS04795
uniprot id: A0A0S3QTR3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1298851:AXH83 RS01435
gene id: 1298851:AXH83_RS01435
uniprot id: A0A0S3QRX8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1298851:AXH83 RS05990
gene id: 1298851:AXH83_RS05990
uniprot id: A0A0S3QUE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1298851:AXH83 RS02990
gene id: 1298851:AXH83_RS02990
uniprot id: A0A0S3QSV9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1298851:AXH83 RS09265
gene id: 1298851:AXH83_RS09265
uniprot id: A0A0S3QW44
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1298851:AXH83 RS04880
gene id: 1298851:AXH83_RS04880
uniprot id: A0A0S3QTU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1298851:AXH83 RS05440
gene id: 1298851:AXH83_RS05440
uniprot id: A0A0S3QU63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1298851:AXH83 RS09575
gene id: 1298851:AXH83_RS09575
uniprot id: A0A0S3QSQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1298851:AXH83 RS02085
gene id: 1298851:AXH83_RS02085
uniprot id: A0A0S3QSE9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1298851:AXH83 RS04510
gene id: 1298851:AXH83_RS04510
uniprot id: A0A0S3QTJ8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1298851:AXH83 RS02080
gene id: 1298851:AXH83_RS02080
uniprot id: A0A0S3QSA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1298851:AXH83 RS00385
gene id: 1298851:AXH83_RS00385
uniprot id: A0A0S3QRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1298851:AXH83 RS05675
gene id: 1298851:AXH83_RS05675
uniprot id: A0A0S3QU69
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS01520
gene id: 1298851:AXH83_RS01520
uniprot id: A0A0S3QS42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS03475
gene id: 1298851:AXH83_RS03475
uniprot id: A0A0S3QT19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS01395
gene id: 1298851:AXH83_RS01395
uniprot id: A0A0S3QRV7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS08115
gene id: 1298851:AXH83_RS08115
uniprot id: A0A0S3QVH2
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1298851:AXH83 RS08655
gene id: 1298851:AXH83_RS08655
uniprot id: A0A0S3QVT7
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS02740
gene id: 1298851:AXH83_RS02740
uniprot id: A0A0S3QSL3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1298851:AXH83 RS03595
gene id: 1298851:AXH83_RS03595
uniprot id: A0A0S3QT53
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1298851:AXH83 RS05610
gene id: 1298851:AXH83_RS05610
uniprot id: A0A0S3QU80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

1298851:AXH83 RS03085
gene id: 1298851:AXH83_RS03085
uniprot id: A0A0S3QSU7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1298851:AXH83 RS06980
gene id: 1298851:AXH83_RS06980
uniprot id: A0A0S3QUX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1298851:AXH83 RS04530
gene id: 1298851:AXH83_RS04530
uniprot id: A0A0S3QTL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1298851:AXH83 RS01675
gene id: 1298851:AXH83_RS01675
uniprot id: A0A0S3QS22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1298851:AXH83 RS06655
gene id: 1298851:AXH83_RS06655
uniprot id: A0A0S3QUS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1298851:AXH83 RS06230
gene id: 1298851:AXH83_RS06230
uniprot id: A0A0S3QUI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1298851:AXH83 RS03035
gene id: 1298851:AXH83_RS03035
uniprot id: A0A0S3QSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1298851:AXH83 RS09230
gene id: 1298851:AXH83_RS09230
uniprot id: A0A0S3QW49
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1298851:AXH83 RS00620
gene id: 1298851:AXH83_RS00620
uniprot id: A0A0S3QRM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1298851:AXH83 RS00740
gene id: 1298851:AXH83_RS00740
uniprot id: A0A0S3QRM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1298851:AXH83 RS04910
gene id: 1298851:AXH83_RS04910
uniprot id: A0A0S3QTS9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1298851:AXH83 RS01500
gene id: 1298851:AXH83_RS01500
uniprot id: A0A0S3QRZ1
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS02940
gene id: 1298851:AXH83_RS02940
uniprot id: A0A0S3QSR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1298851:AXH83 RS00770
gene id: 1298851:AXH83_RS00770
uniprot id: A0A0S3QRJ5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1298851:AXH83 RS04980
gene id: 1298851:AXH83_RS04980
uniprot id: A0A0S3QTU6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS08185
gene id: 1298851:AXH83_RS08185
uniprot id: A0A0S3QVJ1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1298851:AXH83 RS06535
gene id: 1298851:AXH83_RS06535
uniprot id: A0A0S3QUN0
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS05425
gene id: 1298851:AXH83_RS05425
uniprot id: A0A0S3QU33
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1298851:AXH83 RS04025
gene id: 1298851:AXH83_RS04025
uniprot id: A0A0S3QTB7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS04480
gene id: 1298851:AXH83_RS04480
uniprot id: A0A0S3QTK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1298851:AXH83 RS01245
gene id: 1298851:AXH83_RS01245
uniprot id: A0A0S3QRV0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1298851:AXH83 RS02685
gene id: 1298851:AXH83_RS02685
uniprot id: A0A0S3QSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1298851:AXH83 RS04115
gene id: 1298851:AXH83_RS04115
uniprot id: A0A0S3QTC9
names: Similarity
messages: Belongs to the class-I fumarase family.

1298851:AXH83 RS08790
gene id: 1298851:AXH83_RS08790
uniprot id: A0A0S3QVU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1298851:AXH83 RS07240
gene id: 1298851:AXH83_RS07240
uniprot id: A0A0S3QV04
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1298851:AXH83 RS08315
gene id: 1298851:AXH83_RS08315
uniprot id: A0A0S3QVK3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1298851:AXH83 RS03800
gene id: 1298851:AXH83_RS03800
uniprot id: A0A0S3QTB5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1298851:AXH83 RS01455
gene id: 1298851:AXH83_RS01455
uniprot id: A0A0S3QS00
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1298851:AXH83 RS09165
gene id: 1298851:AXH83_RS09165
uniprot id: A0A0S3QW15
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1298851:AXH83 RS03745
gene id: 1298851:AXH83_RS03745
uniprot id: A0A0S3QT58
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS00835
gene id: 1298851:AXH83_RS00835
uniprot id: A0A0S3QRL8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1298851:AXH83 RS06530
gene id: 1298851:AXH83_RS06530
uniprot id: A0A0S3QUN1
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS04630
gene id: 1298851:AXH83_RS04630
uniprot id: A0A0S3QTN0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS08015
gene id: 1298851:AXH83_RS08015
uniprot id: A0A0S3QVF9
names: Similarity
messages: Belongs to the HdrA family.

1298851:AXH83 RS04545
gene id: 1298851:AXH83_RS04545
uniprot id: A0A0S3QTN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1298851:AXH83 RS04740
gene id: 1298851:AXH83_RS04740
uniprot id: A0A0S3QTQ4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1298851:AXH83 RS00605
gene id: 1298851:AXH83_RS00605
uniprot id: A0A0S3QRG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1298851:AXH83 RS02985
gene id: 1298851:AXH83_RS02985
uniprot id: A0A0S3QSR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1298851:AXH83 RS07165
gene id: 1298851:AXH83_RS07165
uniprot id: A0A0S3QV28
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1298851:AXH83 RS07425
gene id: 1298851:AXH83_RS07425
uniprot id: A0A0S3QV36
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1298851:AXH83 RS03095
gene id: 1298851:AXH83_RS03095
uniprot id: A0A0S3QSX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1298851:AXH83 RS08530
gene id: 1298851:AXH83_RS08530
uniprot id: A0A0S3QVQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1298851:AXH83 RS04695
gene id: 1298851:AXH83_RS04695
uniprot id: A0A0S3QTS4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1298851:AXH83 RS07355
gene id: 1298851:AXH83_RS07355
uniprot id: A0A0S3QV43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1298851:AXH83 RS01045
gene id: 1298851:AXH83_RS01045
uniprot id: A0A0S3QRQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS05560
gene id: 1298851:AXH83_RS05560
uniprot id: A0A0S3QU60
names: Similarity
messages: Belongs to the GSP E family.

1298851:AXH83 RS01070
gene id: 1298851:AXH83_RS01070
uniprot id: A0A0S3QRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS01535
gene id: 1298851:AXH83_RS01535
uniprot id: A0A0S3QRZ4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1298851:AXH83 RS05020
gene id: 1298851:AXH83_RS05020
uniprot id: A0A0S3QTU7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1298851:AXH83 RS07555
gene id: 1298851:AXH83_RS07555
uniprot id: A0A0S3QVA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1298851:AXH83 RS02065
gene id: 1298851:AXH83_RS02065
uniprot id: A0A0S3QSC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1298851:AXH83 RS06595
gene id: 1298851:AXH83_RS06595
uniprot id: A0A0S3QUP1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1298851:AXH83 RS05760
gene id: 1298851:AXH83_RS05760
uniprot id: A0A0S3QU91
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1298851:AXH83 RS03690
gene id: 1298851:AXH83_RS03690
uniprot id: A0A0S3QT54
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

1298851:AXH83 RS07495
gene id: 1298851:AXH83_RS07495
uniprot id: A0A0S3QV70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1298851:AXH83 RS00890
gene id: 1298851:AXH83_RS00890
uniprot id: A0A0S3QRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1298851:AXH83 RS03765
gene id: 1298851:AXH83_RS03765
uniprot id: A0A0S3QT83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1298851:AXH83 RS08645
gene id: 1298851:AXH83_RS08645
uniprot id: A0A0S3QVS5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1298851:AXH83 RS03285
gene id: 1298851:AXH83_RS03285
uniprot id: A0A0S3QSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS04110
gene id: 1298851:AXH83_RS04110
uniprot id: A0A0S3QTF8
names: Similarity
messages: Belongs to the class-I fumarase family.

1298851:AXH83 RS09355
gene id: 1298851:AXH83_RS09355
uniprot id: A0A0S3QW47
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS06385
gene id: 1298851:AXH83_RS06385
uniprot id: A0A0S3QUK2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS09100
gene id: 1298851:AXH83_RS09100
uniprot id: A0A0S3QVZ8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1298851:AXH83 RS05930
gene id: 1298851:AXH83_RS05930
uniprot id: A0A0S3QUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS09155
gene id: 1298851:AXH83_RS09155
uniprot id: A0A0S3QW22
names: Similarity
messages: Belongs to the threonine synthase family.

1298851:AXH83 RS06275
gene id: 1298851:AXH83_RS06275
uniprot id: A0A0S3QUJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1298851:AXH83 RS06955
gene id: 1298851:AXH83_RS06955
uniprot id: A0A0S3QUV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1298851:AXH83 RS08005
gene id: 1298851:AXH83_RS08005
uniprot id: A0A0S3QVH1
names: Similarity
messages: Belongs to the HdrA family.

1298851:AXH83 RS08190
gene id: 1298851:AXH83_RS08190
uniprot id: A0A0S3QVJ2
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS09185
gene id: 1298851:AXH83_RS09185
uniprot id: A0A0S3QW30
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1298851:AXH83 RS07375
gene id: 1298851:AXH83_RS07375
uniprot id: A0A0S3QV47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1298851:AXH83 RS07255
gene id: 1298851:AXH83_RS07255
uniprot id: A0A0S3QV29
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS03030
gene id: 1298851:AXH83_RS03030
uniprot id: A0A0S3QSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1298851:AXH83 RS01425
gene id: 1298851:AXH83_RS01425
uniprot id: A0A0S3QRX6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1298851:AXH83 RS03525
gene id: 1298851:AXH83_RS03525
uniprot id: A0A0S3QT30
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1298851:AXH83 RS03780
gene id: 1298851:AXH83_RS03780
uniprot id: A0A0S3QT79
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1298851:AXH83 RS01640
gene id: 1298851:AXH83_RS01640
uniprot id: A0A0S3QS40
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS00560
gene id: 1298851:AXH83_RS00560
uniprot id: A0A0S3QRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1298851:AXH83 RS07585
gene id: 1298851:AXH83_RS07585
uniprot id: A0A0S3QV69
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1298851:AXH83 RS06840
gene id: 1298851:AXH83_RS06840
uniprot id: A0A0S3QUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1298851:AXH83 RS05475
gene id: 1298851:AXH83_RS05475
uniprot id: A0A0S3QU39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1298851:AXH83 RS05795
gene id: 1298851:AXH83_RS05795
uniprot id: A0A0S3QUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1298851:AXH83 RS05145
gene id: 1298851:AXH83_RS05145
uniprot id: A0A0S3QTX1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS06505
gene id: 1298851:AXH83_RS06505
uniprot id: A0A0S3QUL3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1298851:AXH83 RS02910
gene id: 1298851:AXH83_RS02910
uniprot id: A0A0S3QSU0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS07965
gene id: 1298851:AXH83_RS07965
uniprot id: A0A0S3QVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS06635
gene id: 1298851:AXH83_RS06635
uniprot id: A0A0S3QUQ1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1298851:AXH83 RS01460
gene id: 1298851:AXH83_RS01460
uniprot id: A0A0S3QS13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1298851:AXH83 RS02745
gene id: 1298851:AXH83_RS02745
uniprot id: A0A0S3QSS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS02425
gene id: 1298851:AXH83_RS02425
uniprot id: A0A0S3QSG6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1298851:AXH83 RS04750
gene id: 1298851:AXH83_RS04750
uniprot id: A0A0S3QTP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS01860
gene id: 1298851:AXH83_RS01860
uniprot id: A0A0S3QS82
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1298851:AXH83 RS02060
gene id: 1298851:AXH83_RS02060
uniprot id: A0A0S3QSD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1298851:AXH83 RS04665
gene id: 1298851:AXH83_RS04665
uniprot id: A0A0S3QTN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1298851:AXH83 RS05280
gene id: 1298851:AXH83_RS05280
uniprot id: A0A0S3QU01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1298851:AXH83 RS06860
gene id: 1298851:AXH83_RS06860
uniprot id: A0A0S3QUT4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1298851:AXH83 RS07675
gene id: 1298851:AXH83_RS07675
uniprot id: A0A0S3QV82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form.

1298851:AXH83 RS00135
gene id: 1298851:AXH83_RS00135
uniprot id: A0A0S3QR75
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS05190
gene id: 1298851:AXH83_RS05190
uniprot id: A0A0S3QU14
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS07920
gene id: 1298851:AXH83_RS07920
uniprot id: A0A0S3QVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1298851:AXH83 RS02240
gene id: 1298851:AXH83_RS02240
uniprot id: A0A0S3QSE1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1298851:AXH83 RS05960
gene id: 1298851:AXH83_RS05960
uniprot id: A0A0S3QUC7
names: Similarity
messages: Belongs to the peptidase A31 family.

1298851:AXH83 RS01340
gene id: 1298851:AXH83_RS01340
uniprot id: A0A0S3QRW1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1298851:AXH83 RS05840
gene id: 1298851:AXH83_RS05840
uniprot id: A0A0S3QUA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1298851:AXH83 RS00705
gene id: 1298851:AXH83_RS00705
uniprot id: A0A0S3QRH9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1298851:AXH83 RS01040
gene id: 1298851:AXH83_RS01040
uniprot id: A0A0S3QRQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1298851:AXH83 RS07465
gene id: 1298851:AXH83_RS07465
uniprot id: A0A0S3QV60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1298851:AXH83 RS06685
gene id: 1298851:AXH83_RS06685
uniprot id: A0A0S3QUQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1298851:AXH83 RS00305
gene id: 1298851:AXH83_RS00305
uniprot id: A0A0S3QRC6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1298851:AXH83 RS00240
gene id: 1298851:AXH83_RS00240
uniprot id: A0A0S3QR84
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1298851:AXH83 RS02925
gene id: 1298851:AXH83_RS02925
uniprot id: A0A0S3QSR3
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS03365
gene id: 1298851:AXH83_RS03365
uniprot id: A0A0S3QT03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1298851:AXH83 RS04135
gene id: 1298851:AXH83_RS04135
uniprot id: A0A0S3QTC8
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1298851:AXH83 RS07735
gene id: 1298851:AXH83_RS07735
uniprot id: A0A0S3QVA8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1298851:AXH83 RS02750
gene id: 1298851:AXH83_RS02750
uniprot id: A0A0S3QSL9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1298851:AXH83 RS02390
gene id: 1298851:AXH83_RS02390
uniprot id: A0A0S3QSF6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1298851:AXH83 RS09260
gene id: 1298851:AXH83_RS09260
uniprot id: A0A0S3QW42
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1298851:AXH83 RS00025
gene id: 1298851:AXH83_RS00025
uniprot id: A0A0S3QR47
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1298851:AXH83 RS01970
gene id: 1298851:AXH83_RS01970
uniprot id: A0A0S3QS77
names: Similarity
messages: Belongs to the CFA/CMAS family.

1298851:AXH83 RS09300
gene id: 1298851:AXH83_RS09300
uniprot id: A0A0S3QW50
names: Similarity
messages: Belongs to the UPF0173 family.

1298851:AXH83 RS09940
gene id: 1298851:AXH83_RS09940
uniprot id: A0A0S3QVC1
names: Similarity
messages: Belongs to the TrpF family.

1298851:AXH83 RS02375
gene id: 1298851:AXH83_RS02375
uniprot id: A0A0S3QSH5
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS03640
gene id: 1298851:AXH83_RS03640
uniprot id: A0A0S3QT97
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1298851:AXH83 RS01230
gene id: 1298851:AXH83_RS01230
uniprot id: A0A0S3QRV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1298851:AXH83 RS00490
gene id: 1298851:AXH83_RS00490
uniprot id: A0A0S3QRD0
names: Similarity
messages: Belongs to the UPF0111 family.

1298851:AXH83 RS00995
gene id: 1298851:AXH83_RS00995
uniprot id: A0A0S3QRT8
names: Caution
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS04875
gene id: 1298851:AXH83_RS04875
uniprot id: A0A0S3QTT4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1298851:AXH83 RS03325
gene id: 1298851:AXH83_RS03325
uniprot id: A0A0S3QT20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1298851:AXH83 RS04930
gene id: 1298851:AXH83_RS04930
uniprot id: A0A0S3QTV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1298851:AXH83 RS07470
gene id: 1298851:AXH83_RS07470
uniprot id: A0A0S3QV52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1298851:AXH83 RS03730
gene id: 1298851:AXH83_RS03730
uniprot id: A0A0S3QT73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1298851:AXH83 RS01940
gene id: 1298851:AXH83_RS01940
uniprot id: A0A0S3QS99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1298851:AXH83 RS08100
gene id: 1298851:AXH83_RS08100
uniprot id: A0A0S3QVH7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1298851:AXH83 RS08965
gene id: 1298851:AXH83_RS08965
uniprot id: A0A0S3QVZ1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1298851:AXH83 RS02625
gene id: 1298851:AXH83_RS02625
uniprot id: A0A0S3QSP7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

1298851:AXH83 RS04855
gene id: 1298851:AXH83_RS04855
uniprot id: A0A0S3QTV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS02270
gene id: 1298851:AXH83_RS02270
uniprot id: A0A0S3QSF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1298851:AXH83 RS01975
gene id: 1298851:AXH83_RS01975
uniprot id: A0A0S3QS75
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1298851:AXH83 RS00040
gene id: 1298851:AXH83_RS00040
uniprot id: A0A0S3QR74
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1298851:AXH83 RS09365
gene id: 1298851:AXH83_RS09365
uniprot id: A0A0S3QW53
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1298851:AXH83 RS05695
gene id: 1298851:AXH83_RS05695
uniprot id: A0A0S3QU95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1298851:AXH83 RS00245
gene id: 1298851:AXH83_RS00245
uniprot id: A0A0S3QRA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1298851:AXH83 RS06000
gene id: 1298851:AXH83_RS06000
uniprot id: A0A0S3QUE4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1298851:AXH83 RS04460
gene id: 1298851:AXH83_RS04460
uniprot id: A0A0S3QTM7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1298851:AXH83 RS04515
gene id: 1298851:AXH83_RS04515
uniprot id: A0A0S3QTP1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1298851:AXH83 RS02630
gene id: 1298851:AXH83_RS02630
uniprot id: A0A0S3QSJ1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1298851:AXH83 RS09110
gene id: 1298851:AXH83_RS09110
uniprot id: A0A0S3QW13
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS05360
gene id: 1298851:AXH83_RS05360
uniprot id: A0A0S3QU21
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1298851:AXH83 RS00300
gene id: 1298851:AXH83_RS00300
uniprot id: A0A0S3QRB3
names: Similarity
messages: Belongs to the UbiD family.

1298851:AXH83 RS08635
gene id: 1298851:AXH83_RS08635
uniprot id: A0A0S3QVT0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS08585
gene id: 1298851:AXH83_RS08585
uniprot id: A0A0S3QVQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS06820
gene id: 1298851:AXH83_RS06820
uniprot id: A0A0S3QUS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS08780
gene id: 1298851:AXH83_RS08780
uniprot id: A0A0S3QVU9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1298851:AXH83 RS00980
gene id: 1298851:AXH83_RS00980
uniprot id: A0A0S3QRP2
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

1298851:AXH83 RS02675
gene id: 1298851:AXH83_RS02675
uniprot id: A0A0S3QSM8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1298851:AXH83 RS03770
gene id: 1298851:AXH83_RS03770
uniprot id: A0A0S3QT72
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS07975
gene id: 1298851:AXH83_RS07975
uniprot id: A0A0S3QVF7
names: Similarity
messages: Belongs to the LOG family.

1298851:AXH83 RS08200
gene id: 1298851:AXH83_RS08200
uniprot id: A0A0S3QVJ7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1298851:AXH83 RS02480
gene id: 1298851:AXH83_RS02480
uniprot id: A0A0S3QSL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1298851:AXH83 RS05335
gene id: 1298851:AXH83_RS05335
uniprot id: A0A0S3QU20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1298851:AXH83 RS07505
gene id: 1298851:AXH83_RS07505
uniprot id: A0A0S3QV55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1298851:AXH83 RS03650
gene id: 1298851:AXH83_RS03650
uniprot id: A0A0S3QT57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1298851:AXH83 RS04570
gene id: 1298851:AXH83_RS04570
uniprot id: A0A0S3QTQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1298851:AXH83 RS07930
gene id: 1298851:AXH83_RS07930
uniprot id: A0A0S3QVG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS08800
gene id: 1298851:AXH83_RS08800
uniprot id: A0A0S3QVX1
names: Similarity
messages: Belongs to the Skp family.

1298851:AXH83 RS08705
gene id: 1298851:AXH83_RS08705
uniprot id: A0A0S3QVT5
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS06295
gene id: 1298851:AXH83_RS06295
uniprot id: A0A0S3QUI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1298851:AXH83 RS00600
gene id: 1298851:AXH83_RS00600
uniprot id: A0A0S3QRK2
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

1298851:AXH83 RS09705
gene id: 1298851:AXH83_RS09705
uniprot id: A0A0S3QU17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1298851:AXH83 RS03350
gene id: 1298851:AXH83_RS03350
uniprot id: A0A0S3QT28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1298851:AXH83 RS06480
gene id: 1298851:AXH83_RS06480
uniprot id: A0A0S3QUL0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1298851:AXH83 RS07830
gene id: 1298851:AXH83_RS07830
uniprot id: A0A0S3QVF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1298851:AXH83 RS06205
gene id: 1298851:AXH83_RS06205
uniprot id: A0A0S3QUG7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1298851:AXH83 RS06085
gene id: 1298851:AXH83_RS06085
uniprot id: A0A0S3QUF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1298851:AXH83 RS03300
gene id: 1298851:AXH83_RS03300
uniprot id: A0A0S3QSX6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1298851:AXH83 RS01690
gene id: 1298851:AXH83_RS01690
uniprot id: A0A0S3QS31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1298851:AXH83 RS06525
gene id: 1298851:AXH83_RS06525
uniprot id: A0A0S3QUP2
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS02070
gene id: 1298851:AXH83_RS02070
uniprot id: A0A0S3QSA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1298851:AXH83 RS05980
gene id: 1298851:AXH83_RS05980
uniprot id: A0A0S3QUE6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1298851:AXH83 RS08640
gene id: 1298851:AXH83_RS08640
uniprot id: A0A0S3QVS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1298851:AXH83 RS09090
gene id: 1298851:AXH83_RS09090
uniprot id: A0A0S3QVZ7
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS06855
gene id: 1298851:AXH83_RS06855
uniprot id: A0A0S3QUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1298851:AXH83 RS05070
gene id: 1298851:AXH83_RS05070
uniprot id: A0A0S3QTY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS04380
gene id: 1298851:AXH83_RS04380
uniprot id: A0A0S3QTK0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1298851:AXH83 RS08075
gene id: 1298851:AXH83_RS08075
uniprot id: A0A0S3QVG2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1298851:AXH83 RS02410
gene id: 1298851:AXH83_RS02410
uniprot id: A0A0S3QSG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1298851:AXH83 RS00230
gene id: 1298851:AXH83_RS00230
uniprot id: A0A0S3QR88
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS07415
gene id: 1298851:AXH83_RS07415
uniprot id: A0A0S3QV48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1298851:AXH83 RS00610
gene id: 1298851:AXH83_RS00610
uniprot id: A0A0S3QRG6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1298851:AXH83 RS00840
gene id: 1298851:AXH83_RS00840
uniprot id: A0A0S3QRK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1298851:AXH83 RS01585
gene id: 1298851:AXH83_RS01585
uniprot id: A0A0S3QS03
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1298851:AXH83 RS04535
gene id: 1298851:AXH83_RS04535
uniprot id: A0A0S3QTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1298851:AXH83 RS03410
gene id: 1298851:AXH83_RS03410
uniprot id: A0A0S3QT29
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1298851:AXH83 RS04330
gene id: 1298851:AXH83_RS04330
uniprot id: A0A0S3QTG9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1298851:AXH83 RS09105
gene id: 1298851:AXH83_RS09105
uniprot id: A0A0S3QW10
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1298851:AXH83 RS00950
gene id: 1298851:AXH83_RS00950
uniprot id: A0A0S3QRQ0
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1298851:AXH83 RS01870
gene id: 1298851:AXH83_RS01870
uniprot id: A0A0S3QS74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1298851:AXH83 RS06795
gene id: 1298851:AXH83_RS06795
uniprot id: A0A0S3QUS7
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS05025
gene id: 1298851:AXH83_RS05025
uniprot id: A0A0S3QTW4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1298851:AXH83 RS02235
gene id: 1298851:AXH83_RS02235
uniprot id: A0A0S3QSG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1298851:AXH83 RS02405
gene id: 1298851:AXH83_RS02405
uniprot id: A0A0S3QSH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1298851:AXH83 RS00800
gene id: 1298851:AXH83_RS00800
uniprot id: A0A0S3QRK7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS06015
gene id: 1298851:AXH83_RS06015
uniprot id: A0A0S3QUD9
names: Similarity
messages: Belongs to the HypD family.

1298851:AXH83 RS04285
gene id: 1298851:AXH83_RS04285
uniprot id: A0A0S3QTG7
names: Similarity
messages: Belongs to the ribF family.

1298851:AXH83 RS06935
gene id: 1298851:AXH83_RS06935
uniprot id: A0A0S3QUW2
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1298851:AXH83 RS04905
gene id: 1298851:AXH83_RS04905
uniprot id: A0A0S3QTT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1298851:AXH83 RS03360
gene id: 1298851:AXH83_RS03360
uniprot id: A0A0S3QT05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1298851:AXH83 RS08535
gene id: 1298851:AXH83_RS08535
uniprot id: A0A0S3QVQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1298851:AXH83 RS05390
gene id: 1298851:AXH83_RS05390
uniprot id: A0A0S3QU22
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1298851:AXH83 RS08595
gene id: 1298851:AXH83_RS08595
uniprot id: A0A0S3QVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1298851:AXH83 RS01480
gene id: 1298851:AXH83_RS01480
uniprot id: A0A0S3QRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1298851:AXH83 RS09845
gene id: 1298851:AXH83_RS09845
uniprot id: A0A0S3QUS2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1298851:AXH83 RS07220
gene id: 1298851:AXH83_RS07220
uniprot id: A0A0S3QV10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1298851:AXH83 RS08650
gene id: 1298851:AXH83_RS08650
uniprot id: A0A0S3QVS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1298851:AXH83 RS02695
gene id: 1298851:AXH83_RS02695
uniprot id: A0A0S3QSM1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1298851:AXH83 RS03685
gene id: 1298851:AXH83_RS03685
uniprot id: A0A0S3QT68
names: Similarity
messages: Belongs to the CobH/CbiC family.

1298851:AXH83 RS07040
gene id: 1298851:AXH83_RS07040
uniprot id: A0A0S3QUZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS07775
gene id: 1298851:AXH83_RS07775
uniprot id: A0A0S3QVA2
names: Similarity
messages: Belongs to the universal stress protein A family.

1298851:AXH83 RS07670
gene id: 1298851:AXH83_RS07670
uniprot id: A0A0S3QV93
names: Similarity
messages: Belongs to the UPF0045 family.

1298851:AXH83 RS00810
gene id: 1298851:AXH83_RS00810
uniprot id: A0A0S3QRK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1298851:AXH83 RS00450
gene id: 1298851:AXH83_RS00450
uniprot id: A0A0S3QRC5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1298851:AXH83 RS06780
gene id: 1298851:AXH83_RS06780
uniprot id: A0A0S3QUU1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS04655
gene id: 1298851:AXH83_RS04655
uniprot id: A0A0S3QTN1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1298851:AXH83 RS06215
gene id: 1298851:AXH83_RS06215
uniprot id: A0A0S3QUJ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1298851:AXH83 RS05955
gene id: 1298851:AXH83_RS05955
uniprot id: A0A0S3QUC3
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS06825
gene id: 1298851:AXH83_RS06825
uniprot id: A0A0S3QUT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1298851:AXH83 RS05080
gene id: 1298851:AXH83_RS05080
uniprot id: A0A0S3QTW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1298851:AXH83 RS03255
gene id: 1298851:AXH83_RS03255
uniprot id: A0A0S3QSY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1298851:AXH83 RS00665
gene id: 1298851:AXH83_RS00665
uniprot id: A0A0S3QRH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1298851:AXH83 RS04555
gene id: 1298851:AXH83_RS04555
uniprot id: A0A0S3QTK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1298851:AXH83 RS07460
gene id: 1298851:AXH83_RS07460
uniprot id: A0A0S3QV51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1298851:AXH83 RS03395
gene id: 1298851:AXH83_RS03395
uniprot id: A0A0S3QT04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1298851:AXH83 RS03345
gene id: 1298851:AXH83_RS03345
uniprot id: A0A0S3QSY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1298851:AXH83 RS08110
gene id: 1298851:AXH83_RS08110
uniprot id: A0A0S3QVG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS09115
gene id: 1298851:AXH83_RS09115
uniprot id: A0A0S3QW16
names: Similarity
messages: Belongs to the P(II) protein family.

1298851:AXH83 RS07540
gene id: 1298851:AXH83_RS07540
uniprot id: A0A0S3QV65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1298851:AXH83 RS08060
gene id: 1298851:AXH83_RS08060
uniprot id: A0A0S3QVF6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1298851:AXH83 RS04090
gene id: 1298851:AXH83_RS04090
uniprot id: A0A0S3QTC7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1298851:AXH83 RS03775
gene id: 1298851:AXH83_RS03775
uniprot id: A0A0S3QT93
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS00875
gene id: 1298851:AXH83_RS00875
uniprot id: A0A0S3QRL9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1298851:AXH83 RS06305
gene id: 1298851:AXH83_RS06305
uniprot id: A0A0S3QUK8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1298851:AXH83 RS04475
gene id: 1298851:AXH83_RS04475
uniprot id: A0A0S3QTJ4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1298851:AXH83 RS07155
gene id: 1298851:AXH83_RS07155
uniprot id: A0A0S3QV27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1298851:AXH83 RS05445
gene id: 1298851:AXH83_RS05445
uniprot id: A0A0S3QU32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1298851:AXH83 RS08930
gene id: 1298851:AXH83_RS08930
uniprot id: A0A0S3QVY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1298851:AXH83 RS05005
gene id: 1298851:AXH83_RS05005
uniprot id: A0A0S3QTU2
names: Similarity
messages: Belongs to the UPF0102 family.

1298851:AXH83 RS08285
gene id: 1298851:AXH83_RS08285
uniprot id: A0A0S3QVK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1298851:AXH83 RS01980
gene id: 1298851:AXH83_RS01980
uniprot id: A0A0S3QSB7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1298851:AXH83 RS03390
gene id: 1298851:AXH83_RS03390
uniprot id: A0A0S3QSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1298851:AXH83 RS04300
gene id: 1298851:AXH83_RS04300
uniprot id: A0A0S3QTH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1298851:AXH83 RS03915
gene id: 1298851:AXH83_RS03915
uniprot id: A0A0S3QTA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1298851:AXH83 RS00480
gene id: 1298851:AXH83_RS00480
uniprot id: A0A0S3QRE4
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1298851:AXH83 RS04390
gene id: 1298851:AXH83_RS04390
uniprot id: A0A0S3QTH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1298851:AXH83 RS00295
gene id: 1298851:AXH83_RS00295
uniprot id: A0A0S3QRG4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1298851:AXH83 RS05945
gene id: 1298851:AXH83_RS05945
uniprot id: A0A0S3QUC2
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS04725
gene id: 1298851:AXH83_RS04725
uniprot id: A0A0S3QTN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1298851:AXH83 RS03125
gene id: 1298851:AXH83_RS03125
uniprot id: A0A0S3QSU4
names: Similarity
messages: Belongs to the bacterial flagellin family.

1298851:AXH83 RS05380
gene id: 1298851:AXH83_RS05380
uniprot id: A0A0S3QU38
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1298851:AXH83 RS05110
gene id: 1298851:AXH83_RS05110
uniprot id: A0A0S3QTW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1298851:AXH83 RS01010
gene id: 1298851:AXH83_RS01010
uniprot id: A0A0S3QRP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS02590
gene id: 1298851:AXH83_RS02590
uniprot id: A0A0S3QSK4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1298851:AXH83 RS03895
gene id: 1298851:AXH83_RS03895
uniprot id: A0A0S3QT98
names: Similarity
messages: Belongs to the UPF0166 family.

1298851:AXH83 RS03355
gene id: 1298851:AXH83_RS03355
uniprot id: A0A0S3QSY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1298851:AXH83 RS02720
gene id: 1298851:AXH83_RS02720
uniprot id: A0A0S3QSK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1298851:AXH83 RS07225
gene id: 1298851:AXH83_RS07225
uniprot id: A0A0S3QV09
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS00760
gene id: 1298851:AXH83_RS00760
uniprot id: A0A0S3QRN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1298851:AXH83 RS04560
gene id: 1298851:AXH83_RS04560
uniprot id: A0A0S3QTM1
names: Similarity
messages: Belongs to the ParB family.

1298851:AXH83 RS04470
gene id: 1298851:AXH83_RS04470
uniprot id: A0A0S3QTJ2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1298851:AXH83 RS04325
gene id: 1298851:AXH83_RS04325
uniprot id: A0A0S3QTK8
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1298851:AXH83 RS07490
gene id: 1298851:AXH83_RS07490
uniprot id: A0A0S3QV50
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1298851:AXH83 RS07245
gene id: 1298851:AXH83_RS07245
uniprot id: A0A0S3QV01
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1298851:AXH83 RS03315
gene id: 1298851:AXH83_RS03315
uniprot id: A0A0S3QSZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1298851:AXH83 RS00570
gene id: 1298851:AXH83_RS00570
uniprot id: A0A0S3QRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1298851:AXH83 RS05535
gene id: 1298851:AXH83_RS05535
uniprot id: A0A0S3QU52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1298851:AXH83 RS05455
gene id: 1298851:AXH83_RS05455
uniprot id: A0A0S3QU41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1298851:AXH83 RS05510
gene id: 1298851:AXH83_RS05510
uniprot id: A0A0S3QU40
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS02970
gene id: 1298851:AXH83_RS02970
uniprot id: A0A0S3QSQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS06650
gene id: 1298851:AXH83_RS06650
uniprot id: A0A0S3QUP9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS07160
gene id: 1298851:AXH83_RS07160
uniprot id: A0A0S3QV13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1298851:AXH83 RS08440
gene id: 1298851:AXH83_RS08440
uniprot id: A0A0S3QVM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1298851:AXH83 RS04605
gene id: 1298851:AXH83_RS04605
uniprot id: A0A0S3QTN2
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1298851:AXH83 RS00815
gene id: 1298851:AXH83_RS00815
uniprot id: A0A0S3QRN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1298851:AXH83 RS08330
gene id: 1298851:AXH83_RS08330
uniprot id: A0A0S3QVL5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1298851:AXH83 RS06090
gene id: 1298851:AXH83_RS06090
uniprot id: A0A0S3QUF0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1298851:AXH83 RS06415
gene id: 1298851:AXH83_RS06415
uniprot id: A0A0S3QUM3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1298851:AXH83 RS01545
gene id: 1298851:AXH83_RS01545
uniprot id: A0A0S3QS14
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1298851:AXH83 RS00520
gene id: 1298851:AXH83_RS00520
uniprot id: A0A0S3QRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1298851:AXH83 RS02455
gene id: 1298851:AXH83_RS02455
uniprot id: A0A0S3QSH1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1298851:AXH83 RS00105
gene id: 1298851:AXH83_RS00105
uniprot id: A0A0S3QR70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1298851:AXH83 RS01250
gene id: 1298851:AXH83_RS01250
uniprot id: A0A0S3QRT7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1298851:AXH83 RS06885
gene id: 1298851:AXH83_RS06885
uniprot id: A0A0S3QUT6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1298851:AXH83 RS09225
gene id: 1298851:AXH83_RS09225
uniprot id: A0A0S3QW40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS06080
gene id: 1298851:AXH83_RS06080
uniprot id: A0A0S3QUH1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1298851:AXH83 RS08590
gene id: 1298851:AXH83_RS08590
uniprot id: A0A0S3QVQ7
names: Similarity
messages: Belongs to the GSP E family.

1298851:AXH83 RS06485
gene id: 1298851:AXH83_RS06485
uniprot id: A0A0S3QUL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1298851:AXH83 RS06755
gene id: 1298851:AXH83_RS06755
uniprot id: A0A0S3QUS1
names: Similarity
messages: Belongs to the pyruvate kinase family.

1298851:AXH83 RS09080
gene id: 1298851:AXH83_RS09080
uniprot id: A0A0S3QW02
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS02420
gene id: 1298851:AXH83_RS02420
uniprot id: A0A0S3QSL0
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1298851:AXH83 RS05555
gene id: 1298851:AXH83_RS05555
uniprot id: A0A0S3QU55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1298851:AXH83 RS09085
gene id: 1298851:AXH83_RS09085
uniprot id: A0A0S3QW08
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1298851:AXH83 RS09215
gene id: 1298851:AXH83_RS09215
uniprot id: A0A0S3QW29
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1298851:AXH83 RS04145
gene id: 1298851:AXH83_RS04145
uniprot id: A0A0S3QTD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1298851:AXH83 RS04360
gene id: 1298851:AXH83_RS04360
uniprot id: A0A0S3QTI8
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

1298851:AXH83 RS02440
gene id: 1298851:AXH83_RS02440
uniprot id: A0A0S3QSI4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1298851:AXH83 RS07795
gene id: 1298851:AXH83_RS07795
uniprot id: A0A0S3QVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1298851:AXH83 RS07380
gene id: 1298851:AXH83_RS07380
uniprot id: A0A0S3QV41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1298851:AXH83 RS03605
gene id: 1298851:AXH83_RS03605
uniprot id: A0A0S3QT34
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1298851:AXH83 RS07395
gene id: 1298851:AXH83_RS07395
uniprot id: A0A0S3QV66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1298851:AXH83 RS08770
gene id: 1298851:AXH83_RS08770
uniprot id: A0A0S3QVU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1298851:AXH83 RS01205
gene id: 1298851:AXH83_RS01205
uniprot id: A0A0S3QRT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1298851:AXH83 RS06515
gene id: 1298851:AXH83_RS06515
uniprot id: A0A0S3QUM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1298851:AXH83 RS07790
gene id: 1298851:AXH83_RS07790
uniprot id: A0A0S3QVB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS05635
gene id: 1298851:AXH83_RS05635
uniprot id: A0A0S3QU93
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1298851:AXH83 RS01590
gene id: 1298851:AXH83_RS01590
uniprot id: A0A0S3QS12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1298851:AXH83 RS09275
gene id: 1298851:AXH83_RS09275
uniprot id: A0A0S3QW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1298851:AXH83 RS03050
gene id: 1298851:AXH83_RS03050
uniprot id: A0A0S3QSR8
names: Similarity
messages: Belongs to the acylphosphatase family.

1298851:AXH83 RS03485
gene id: 1298851:AXH83_RS03485
uniprot id: A0A0S3QT13
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1298851:AXH83 RS02770
gene id: 1298851:AXH83_RS02770
uniprot id: A0A0S3QSR4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1298851:AXH83 RS00400
gene id: 1298851:AXH83_RS00400
uniprot id: A0A0S3QRC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1298851:AXH83 RS07825
gene id: 1298851:AXH83_RS07825
uniprot id: A0A0S3QVD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1298851:AXH83 RS02475
gene id: 1298851:AXH83_RS02475
uniprot id: A0A0S3QSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1298851:AXH83 RS01790
gene id: 1298851:AXH83_RS01790
uniprot id: A0A0S3QS62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1298851:AXH83 RS07130
gene id: 1298851:AXH83_RS07130
uniprot id: A0A0S3QUY9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1298851:AXH83 RS03405
gene id: 1298851:AXH83_RS03405
uniprot id: A0A0S3QSZ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1298851:AXH83 RS01420
gene id: 1298851:AXH83_RS01420
uniprot id: A0A0S3QRX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1298851:AXH83 RS02810
gene id: 1298851:AXH83_RS02810
uniprot id: A0A0S3QSM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1298851:AXH83 RS07525
gene id: 1298851:AXH83_RS07525
uniprot id: A0A0S3QV53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1298851:AXH83 RS07435
gene id: 1298851:AXH83_RS07435
uniprot id: A0A0S3QV54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1298851:AXH83 RS08235
gene id: 1298851:AXH83_RS08235
uniprot id: A0A0S3QVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1298851:AXH83 RS03135
gene id: 1298851:AXH83_RS03135
uniprot id: A0A0S3QSW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1298851:AXH83 RS00855
gene id: 1298851:AXH83_RS00855
uniprot id: A0A0S3QRL5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1298851:AXH83 RS04450
gene id: 1298851:AXH83_RS04450
uniprot id: A0A0S3QTL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1298851:AXH83 RS06500
gene id: 1298851:AXH83_RS06500
uniprot id: A0A0S3QUN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1298851:AXH83 RS05630
gene id: 1298851:AXH83_RS05630
uniprot id: A0A0S3QU88
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS09380
gene id: 1298851:AXH83_RS09380
uniprot id: A0A0S3QW69
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1298851:AXH83 RS02380
gene id: 1298851:AXH83_RS02380
uniprot id: A0A0S3QSG7
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1298851:AXH83 RS03500
gene id: 1298851:AXH83_RS03500
uniprot id: A0A0S3QT23
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1298851:AXH83 RS03420
gene id: 1298851:AXH83_RS03420
uniprot id: A0A0S3QT09
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1298851:AXH83 RS05295
gene id: 1298851:AXH83_RS05295
uniprot id: A0A0S3QU27
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1298851:AXH83 RS01060
gene id: 1298851:AXH83_RS01060
uniprot id: A0A0S3QRQ8
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS06920
gene id: 1298851:AXH83_RS06920
uniprot id: A0A0S3QUW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1298851:AXH83 RS07685
gene id: 1298851:AXH83_RS07685
uniprot id: A0A0S3QV89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1298851:AXH83 RS01805
gene id: 1298851:AXH83_RS01805
uniprot id: A0A0S3QS71
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS00565
gene id: 1298851:AXH83_RS00565
uniprot id: A0A0S3QRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1298851:AXH83 RS00910
gene id: 1298851:AXH83_RS00910
uniprot id: A0A0S3QRS2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1298851:AXH83 RS08495
gene id: 1298851:AXH83_RS08495
uniprot id: A0A0S3QVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS05685
gene id: 1298851:AXH83_RS05685
uniprot id: A0A0S3QU85
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1298851:AXH83 RS07445
gene id: 1298851:AXH83_RS07445
uniprot id: A0A0S3QV35
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1298851:AXH83 RS02005
gene id: 1298851:AXH83_RS02005
uniprot id: A0A0S3QSD8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1298851:AXH83 RS07405
gene id: 1298851:AXH83_RS07405
uniprot id: A0A0S3QV38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1298851:AXH83 RS00500
gene id: 1298851:AXH83_RS00500
uniprot id: A0A0S3QRD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1298851:AXH83 RS04425
gene id: 1298851:AXH83_RS04425
uniprot id: A0A0S3QTI9
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS06150
gene id: 1298851:AXH83_RS06150
uniprot id: A0A0S3QUH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1298851:AXH83 RS06225
gene id: 1298851:AXH83_RS06225
uniprot id: A0A0S3QUI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1298851:AXH83 RS01540
gene id: 1298851:AXH83_RS01540
uniprot id: A0A0S3QS10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1298851:AXH83 RS01080
gene id: 1298851:AXH83_RS01080
uniprot id: A0A0S3QRR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1298851:AXH83 RS07655
gene id: 1298851:AXH83_RS07655
uniprot id: A0A0S3QVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1298851:AXH83 RS07535
gene id: 1298851:AXH83_RS07535
uniprot id: A0A0S3QV87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1298851:AXH83 RS05845
gene id: 1298851:AXH83_RS05845
uniprot id: A0A0S3QUA1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1298851:AXH83 RS06615
gene id: 1298851:AXH83_RS06615
uniprot id: A0A0S3QUP3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1298851:AXH83 RS06600
gene id: 1298851:AXH83_RS06600
uniprot id: A0A0S3QUP7
names: Similarity
messages: Belongs to the aspartokinase family.

1298851:AXH83 RS04125
gene id: 1298851:AXH83_RS04125
uniprot id: A0A0S3QTE5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1298851:AXH83 RS01925
gene id: 1298851:AXH83_RS01925
uniprot id: A0A0S3QSC2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1298851:AXH83 RS02295
gene id: 1298851:AXH83_RS02295
uniprot id: A0A0S3QSG1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1298851:AXH83 RS08745
gene id: 1298851:AXH83_RS08745
uniprot id: A0A0S3QVU1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1298851:AXH83 RS06995
gene id: 1298851:AXH83_RS06995
uniprot id: A0A0S3QUZ4
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS07810
gene id: 1298851:AXH83_RS07810
uniprot id: A0A0S3QVD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1298851:AXH83 RS04340
gene id: 1298851:AXH83_RS04340
uniprot id: A0A0S3QTH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1298851:AXH83 RS00365
gene id: 1298851:AXH83_RS00365
uniprot id: A0A0S3QRD2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1298851:AXH83 RS08135
gene id: 1298851:AXH83_RS08135
uniprot id: A0A0S3QVG6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1298851:AXH83 RS02830
gene id: 1298851:AXH83_RS02830
uniprot id: A0A0S3QST2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS00125
gene id: 1298851:AXH83_RS00125
uniprot id: A0A0S3QR71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1298851:AXH83 RS07660
gene id: 1298851:AXH83_RS07660
uniprot id: A0A0S3QVB9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS06395
gene id: 1298851:AXH83_RS06395
uniprot id: A0A0S3QUL2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1298851:AXH83 RS08690
gene id: 1298851:AXH83_RS08690
uniprot id: A0A0S3QVT4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1298851:AXH83 RS07550
gene id: 1298851:AXH83_RS07550
uniprot id: A0A0S3QV67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1298851:AXH83 RS07480
gene id: 1298851:AXH83_RS07480
uniprot id: A0A0S3QV58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1298851:AXH83 RS00595
gene id: 1298851:AXH83_RS00595
uniprot id: A0A0S3QRG1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1298851:AXH83 RS09805
gene id: 1298851:AXH83_RS09805
uniprot id: A0A0S3QRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1298851:AXH83 RS07545
gene id: 1298851:AXH83_RS07545
uniprot id: A0A0S3QV73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1298851:AXH83 RS00075
gene id: 1298851:AXH83_RS00075
uniprot id: A0A0S3QR62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1298851:AXH83 RS00360
gene id: 1298851:AXH83_RS00360
uniprot id: A0A0S3QRC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1298851:AXH83 RS09335
gene id: 1298851:AXH83_RS09335
uniprot id: A0A0S3QW77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1298851:AXH83 RS09030
gene id: 1298851:AXH83_RS09030
uniprot id: A0A0S3QW00
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1298851:AXH83 RS04540
gene id: 1298851:AXH83_RS04540
uniprot id: A0A0S3QTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1298851:AXH83 RS06005
gene id: 1298851:AXH83_RS06005
uniprot id: A0A0S3QUC8
names: Similarity
messages: Belongs to the HupF/HypC family.

1298851:AXH83 RS03710
gene id: 1298851:AXH83_RS03710
uniprot id: A0A0S3QT69
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS08065
gene id: 1298851:AXH83_RS08065
uniprot id: A0A0S3QVH5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1298851:AXH83 RS02835
gene id: 1298851:AXH83_RS02835
uniprot id: A0A0S3QSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS05935
gene id: 1298851:AXH83_RS05935
uniprot id: A0A0S3QUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS00780
gene id: 1298851:AXH83_RS00780
uniprot id: A0A0S3QRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1298851:AXH83 RS00275
gene id: 1298851:AXH83_RS00275
uniprot id: A0A0S3QRD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1298851:AXH83 RS05375
gene id: 1298851:AXH83_RS05375
uniprot id: A0A0S3QU37
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1298851:AXH83 RS01515
gene id: 1298851:AXH83_RS01515
uniprot id: A0A0S3QRZ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1298851:AXH83 RS04915
gene id: 1298851:AXH83_RS04915
uniprot id: A0A0S3QTS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1298851:AXH83 RS05345
gene id: 1298851:AXH83_RS05345
uniprot id: A0A0S3QU15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1298851:AXH83 RS01180
gene id: 1298851:AXH83_RS01180
uniprot id: A0A0S3QRS6
names: Similarity
messages: Belongs to the OprB family.

1298851:AXH83 RS04120
gene id: 1298851:AXH83_RS04120
uniprot id: A0A0S3QTE3
names: Cofactor
names: Similarity
messages: Belongs to the cytochrome b560 family.
messages: The heme is bound between the two transmembrane subunits.

1298851:AXH83 RS04550
gene id: 1298851:AXH83_RS04550
uniprot id: A0A0S3QTL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1298851:AXH83 RS02445
gene id: 1298851:AXH83_RS02445
uniprot id: A0A0S3QSH2
names: Similarity
messages: Belongs to the UPF0235 family.

1298851:AXH83 RS01580
gene id: 1298851:AXH83_RS01580
uniprot id: A0A0S3QS44
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1298851:AXH83 RS03695
gene id: 1298851:AXH83_RS03695
uniprot id: A0A0S3QT81
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1298851:AXH83 RS02980
gene id: 1298851:AXH83_RS02980
uniprot id: A0A0S3QST3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1298851:AXH83 RS02845
gene id: 1298851:AXH83_RS02845
uniprot id: A0A0S3QSP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS06945
gene id: 1298851:AXH83_RS06945
uniprot id: A0A0S3QUV3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1298851:AXH83 RS04840
gene id: 1298851:AXH83_RS04840
uniprot id: A0A0S3QTR2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1298851:AXH83 RS00965
gene id: 1298851:AXH83_RS00965
uniprot id: A0A0S3QRP9
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS00215
gene id: 1298851:AXH83_RS00215
uniprot id: A0A0S3QR99
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1298851:AXH83 RS06940
gene id: 1298851:AXH83_RS06940
uniprot id: A0A0S3QUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1298851:AXH83 RS06970
gene id: 1298851:AXH83_RS06970
uniprot id: A0A0S3QUV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1298851:AXH83 RS04815
gene id: 1298851:AXH83_RS04815
uniprot id: A0A0S3QTR6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1298851:AXH83 RS05225
gene id: 1298851:AXH83_RS05225
uniprot id: A0A0S3QTZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1298851:AXH83 RS09935
gene id: 1298851:AXH83_RS09935
uniprot id: A0A0S3QV97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1298851:AXH83 RS05325
gene id: 1298851:AXH83_RS05325
uniprot id: A0A0S3QU34
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1298851:AXH83 RS08975
gene id: 1298851:AXH83_RS08975
uniprot id: A0A0S3QVZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1298851:AXH83 RS01700
gene id: 1298851:AXH83_RS01700
uniprot id: A0A0S3QS41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS02795
gene id: 1298851:AXH83_RS02795
uniprot id: A0A0S3QSM6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1298851:AXH83 RS07440
gene id: 1298851:AXH83_RS07440
uniprot id: A0A0S3QV68
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1298851:AXH83 RS02165
gene id: 1298851:AXH83_RS02165
uniprot id: A0A0S3QSH0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS00395
gene id: 1298851:AXH83_RS00395
uniprot id: A0A0S3QRC3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

1298851:AXH83 RS03320
gene id: 1298851:AXH83_RS03320
uniprot id: A0A0S3QSY1
names: Similarity
messages: Belongs to the MotB family.

1298851:AXH83 RS04005
gene id: 1298851:AXH83_RS04005
uniprot id: A0A0S3QTC2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1298851:AXH83 RS05265
gene id: 1298851:AXH83_RS05265
uniprot id: A0A0S3QU12
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1298851:AXH83 RS07610
gene id: 1298851:AXH83_RS07610
uniprot id: A0A0S3QV65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1298851:AXH83 RS03235
gene id: 1298851:AXH83_RS03235
uniprot id: A0A0S3QSY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1298851:AXH83 RS03265
gene id: 1298851:AXH83_RS03265
uniprot id: A0A0S3QSX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1298851:AXH83 RS06160
gene id: 1298851:AXH83_RS06160
uniprot id: A0A0S3QUJ8
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS08275
gene id: 1298851:AXH83_RS08275
uniprot id: A0A0S3QVK2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1298851:AXH83 RS02355
gene id: 1298851:AXH83_RS02355
uniprot id: A0A0S3QSG5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1298851:AXH83 RS01725
gene id: 1298851:AXH83_RS01725
uniprot id: A0A0S3QS29
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1298851:AXH83 RS01720
gene id: 1298851:AXH83_RS01720
uniprot id: A0A0S3QS50
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1298851:AXH83 RS05055
gene id: 1298851:AXH83_RS05055
uniprot id: A0A0S3QTV7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1298851:AXH83 RS08095
gene id: 1298851:AXH83_RS08095
uniprot id: A0A0S3QVH0
names: Similarity
messages: Belongs to the GARS family.

1298851:AXH83 RS05120
gene id: 1298851:AXH83_RS05120
uniprot id: A0A0S3QTY5
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS08830
gene id: 1298851:AXH83_RS08830
uniprot id: A0A0S3QVW0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1298851:AXH83 RS00350
gene id: 1298851:AXH83_RS00350
uniprot id: A0A0S3QRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1298851:AXH83 RS02000
gene id: 1298851:AXH83_RS02000
uniprot id: A0A0S3QS93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1298851:AXH83 RS03065
gene id: 1298851:AXH83_RS03065
uniprot id: A0A0S3QSS5
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1298851:AXH83 RS04660
gene id: 1298851:AXH83_RS04660
uniprot id: A0A0S3QTP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1298851:AXH83 RS04345
gene id: 1298851:AXH83_RS04345
uniprot id: A0A0S3QTH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS02360
gene id: 1298851:AXH83_RS02360
uniprot id: A0A0S3QSG3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1298851:AXH83 RS06130
gene id: 1298851:AXH83_RS06130
uniprot id: A0A0S3QUH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1298851:AXH83 RS01620
gene id: 1298851:AXH83_RS01620
uniprot id: A0A0S3QS28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1298851:AXH83 RS08625
gene id: 1298851:AXH83_RS08625
uniprot id: A0A0S3QVR7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1298851:AXH83 RS08995
gene id: 1298851:AXH83_RS08995
uniprot id: A0A0S3QVZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1298851:AXH83 RS08875
gene id: 1298851:AXH83_RS08875
uniprot id: A0A0S3QVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

1298851:AXH83 RS02500
gene id: 1298851:AXH83_RS02500
uniprot id: A0A0S3QSK1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1298851:AXH83 RS00825
gene id: 1298851:AXH83_RS00825
uniprot id: A0A0S3QRL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1298851:AXH83 RS04385
gene id: 1298851:AXH83_RS04385
uniprot id: A0A0S3QTI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1298851:AXH83 RS09930
gene id: 1298851:AXH83_RS09930
uniprot id: A0A0S3QUY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1298851:AXH83 RS07515
gene id: 1298851:AXH83_RS07515
uniprot id: A0A0S3QV77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1298851:AXH83 RS06520
gene id: 1298851:AXH83_RS06520
uniprot id: A0A0S3QUM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1298851:AXH83 RS01370
gene id: 1298851:AXH83_RS01370
uniprot id: A0A0S3QRX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1298851:AXH83 RS01055
gene id: 1298851:AXH83_RS01055
uniprot id: A0A0S3QRT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS03205
gene id: 1298851:AXH83_RS03205
uniprot id: A0A0S3QSW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1298851:AXH83 RS07370
gene id: 1298851:AXH83_RS07370
uniprot id: A0A0S3QV42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1298851:AXH83 RS04370
gene id: 1298851:AXH83_RS04370
uniprot id: A0A0S3QTK4
names: Similarity
messages: Belongs to the peptidase S58 family.

1298851:AXH83 RS04755
gene id: 1298851:AXH83_RS04755
uniprot id: A0A0S3QTT1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1298851:AXH83 RS00795
gene id: 1298851:AXH83_RS00795
uniprot id: A0A0S3QRK4
names: Similarity
messages: Belongs to the UPF0758 family.

1298851:AXH83 RS01195
gene id: 1298851:AXH83_RS01195
uniprot id: A0A0S3QRU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1298851:AXH83 RS00355
gene id: 1298851:AXH83_RS00355
uniprot id: A0A0S3QRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS03100
gene id: 1298851:AXH83_RS03100
uniprot id: A0A0S3QST6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1298851:AXH83 RS07580
gene id: 1298851:AXH83_RS07580
uniprot id: A0A0S3QV72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1298851:AXH83 RS06285
gene id: 1298851:AXH83_RS06285
uniprot id: A0A0S3QUJ3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1298851:AXH83 RS02765
gene id: 1298851:AXH83_RS02765
uniprot id: A0A0S3QSM5
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS08155
gene id: 1298851:AXH83_RS08155
uniprot id: A0A0S3QVI3
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS00625
gene id: 1298851:AXH83_RS00625
uniprot id: A0A0S3QRG7
names: Similarity
messages: Belongs to the UPF0128 family.

1298851:AXH83 RS08665
gene id: 1298851:AXH83_RS08665
uniprot id: A0A0S3QVR9
names: Similarity
messages: Belongs to the UPF0434 family.

1298851:AXH83 RS05105
gene id: 1298851:AXH83_RS05105
uniprot id: A0A0S3QTY4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1298851:AXH83 RS08935
gene id: 1298851:AXH83_RS08935
uniprot id: A0A0S3QVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1298851:AXH83 RS08210
gene id: 1298851:AXH83_RS08210
uniprot id: A0A0S3QVJ3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1298851:AXH83 RS08890
gene id: 1298851:AXH83_RS08890
uniprot id: A0A0S3QVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1298851:AXH83 RS08740
gene id: 1298851:AXH83_RS08740
uniprot id: A0A0S3QVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1298851:AXH83 RS03195
gene id: 1298851:AXH83_RS03195
uniprot id: A0A0S3QSV6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1298851:AXH83 RS07455
gene id: 1298851:AXH83_RS07455
uniprot id: A0A0S3QV62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1298851:AXH83 RS09045
gene id: 1298851:AXH83_RS09045
uniprot id: A0A0S3QW06
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS05565
gene id: 1298851:AXH83_RS05565
uniprot id: A0A0S3QU76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1298851:AXH83 RS08105
gene id: 1298851:AXH83_RS08105
uniprot id: A0A0S3QVG8
names: Similarity
messages: Belongs to the GSP E family.

1298851:AXH83 RS05970
gene id: 1298851:AXH83_RS05970
uniprot id: A0A0S3QUF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1298851:AXH83 RS07945
gene id: 1298851:AXH83_RS07945
uniprot id: A0A0S3QVC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1298851:AXH83 RS06290
gene id: 1298851:AXH83_RS06290
uniprot id: A0A0S3QUK1
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1298851:AXH83 RS01560
gene id: 1298851:AXH83_RS01560
uniprot id: A0A0S3QS24
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1298851:AXH83 RS06585
gene id: 1298851:AXH83_RS06585
uniprot id: A0A0S3QUQ7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1298851:AXH83 RS04615
gene id: 1298851:AXH83_RS04615
uniprot id: A0A0S3QTR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1298851:AXH83 RS02020
gene id: 1298851:AXH83_RS02020
uniprot id: A0A0S3QSB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1298851:AXH83 RS04685
gene id: 1298851:AXH83_RS04685
uniprot id: A0A0S3QTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1298851:AXH83 RS07680
gene id: 1298851:AXH83_RS07680
uniprot id: A0A0S3QV91
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1298851:AXH83 RS07530
gene id: 1298851:AXH83_RS07530
uniprot id: A0A0S3QV74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1298851:AXH83 RS03155
gene id: 1298851:AXH83_RS03155
uniprot id: A0A0S3QSY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1298851:AXH83 RS05125
gene id: 1298851:AXH83_RS05125
uniprot id: A0A0S3QTZ5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1298851:AXH83 RS08570
gene id: 1298851:AXH83_RS08570
uniprot id: A0A0S3QVR3
names: Similarity
messages: Belongs to the P(II) protein family.

1298851:AXH83 RS07605
gene id: 1298851:AXH83_RS07605
uniprot id: A0A0S3QV95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1298851:AXH83 RS05135
gene id: 1298851:AXH83_RS05135
uniprot id: A0A0S3QTX3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS07050
gene id: 1298851:AXH83_RS07050
uniprot id: A0A0S3QUX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1298851:AXH83 RS03385
gene id: 1298851:AXH83_RS03385
uniprot id: A0A0S3QSZ5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1298851:AXH83 RS01375
gene id: 1298851:AXH83_RS01375
uniprot id: A0A0S3QRX7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1298851:AXH83 RS06095
gene id: 1298851:AXH83_RS06095
uniprot id: A0A0S3QUG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1298851:AXH83 RS04885
gene id: 1298851:AXH83_RS04885
uniprot id: A0A0S3QTS3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1298851:AXH83 RS03270
gene id: 1298851:AXH83_RS03270
uniprot id: A0A0S3QT08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of 2 proteins (FliG, FliN) that might form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1298851:AXH83 RS01365
gene id: 1298851:AXH83_RS01365
uniprot id: A0A0S3QRX0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1298851:AXH83 RS00990
gene id: 1298851:AXH83_RS00990
uniprot id: A0A0S3QRP4
names: Similarity
messages: Belongs to the ycf81 family.

1298851:AXH83 RS00050
gene id: 1298851:AXH83_RS00050
uniprot id: A0A0S3QR53
names: Similarity
messages: Belongs to the glutamate synthase family.

1298851:AXH83 RS04430
gene id: 1298851:AXH83_RS04430
uniprot id: A0A0S3QTM8
names: Similarity
messages: Belongs to the RecJ family.

1298851:AXH83 RS04765
gene id: 1298851:AXH83_RS04765
uniprot id: A0A0S3QTQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS05065
gene id: 1298851:AXH83_RS05065
uniprot id: A0A0S3QTW1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1298851:AXH83 RS01495
gene id: 1298851:AXH83_RS01495
uniprot id: A0A0S3QS23
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1298851:AXH83 RS08775
gene id: 1298851:AXH83_RS08775
uniprot id: A0A0S3QVU2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS01680
gene id: 1298851:AXH83_RS01680
uniprot id: A0A0S3QS78
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1298851:AXH83 RS01800
gene id: 1298851:AXH83_RS01800
uniprot id: A0A0S3QS55
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1298851:AXH83 RS06490
gene id: 1298851:AXH83_RS06490
uniprot id: A0A0S3QUN9
names: Similarity
messages: Belongs to the NusB family.

1298851:AXH83 RS07390
gene id: 1298851:AXH83_RS07390
uniprot id: A0A0S3QV34
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1298851:AXH83 RS05255
gene id: 1298851:AXH83_RS05255
uniprot id: A0A0S3QU03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1298851:AXH83 RS00200
gene id: 1298851:AXH83_RS00200
uniprot id: A0A0S3QR90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1298851:AXH83 RS08520
gene id: 1298851:AXH83_RS08520
uniprot id: A0A0S3QVP6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1298851:AXH83 RS05240
gene id: 1298851:AXH83_RS05240
uniprot id: A0A0S3QTZ9
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS09200
gene id: 1298851:AXH83_RS09200
uniprot id: A0A0S3QW31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1298851:AXH83 RS06200
gene id: 1298851:AXH83_RS06200
uniprot id: A0A0S3QUH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1298851:AXH83 RS07230
gene id: 1298851:AXH83_RS07230
uniprot id: A0A0S3QV05
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS05905
gene id: 1298851:AXH83_RS05905
uniprot id: A0A0S3QUD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1298851:AXH83 RS04595
gene id: 1298851:AXH83_RS04595
uniprot id: A0A0S3QTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1298851:AXH83 RS00470
gene id: 1298851:AXH83_RS00470
uniprot id: A0A0S3QRD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1298851:AXH83 RS07015
gene id: 1298851:AXH83_RS07015
uniprot id: A0A0S3QUX0
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1298851:AXH83 RS07400
gene id: 1298851:AXH83_RS07400
uniprot id: A0A0S3QV32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1298851:AXH83 RS03330
gene id: 1298851:AXH83_RS03330
uniprot id: A0A0S3QSZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1298851:AXH83 RS07450
gene id: 1298851:AXH83_RS07450
uniprot id: A0A0S3QV61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1298851:AXH83 RS09240
gene id: 1298851:AXH83_RS09240
uniprot id: A0A0S3QW32
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1298851:AXH83 RS02300
gene id: 1298851:AXH83_RS02300
uniprot id: A0A0S3QSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1298851:AXH83 RS04140
gene id: 1298851:AXH83_RS04140
uniprot id: A0A0S3QTE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1298851:AXH83 RS02180
gene id: 1298851:AXH83_RS02180
uniprot id: A0A0S3QSE3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS02450
gene id: 1298851:AXH83_RS02450
uniprot id: A0A0S3QSL6
names: Similarity
messages: Belongs to the YggT family.

1298851:AXH83 RS04230
gene id: 1298851:AXH83_RS04230
uniprot id: A0A0S3QTE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1298851:AXH83 RS07310
gene id: 1298851:AXH83_RS07310
uniprot id: A0A0S3QV18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1298851:AXH83 RS04835
gene id: 1298851:AXH83_RS04835
uniprot id: A0A0S3QTT8
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS03965
gene id: 1298851:AXH83_RS03965
uniprot id: A0A0S3QTB8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1298851:AXH83 RS06640
gene id: 1298851:AXH83_RS06640
uniprot id: A0A0S3QUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1298851:AXH83 RS02225
gene id: 1298851:AXH83_RS02225
uniprot id: A0A0S3QSF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1298851:AXH83 RS02350
gene id: 1298851:AXH83_RS02350
uniprot id: A0A0S3QSI1
names: Subcellular Location Annotation
messages: Membrane

1298851:AXH83 RS09330
gene id: 1298851:AXH83_RS09330
uniprot id: A0A0S3QW43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1298851:AXH83 RS03260
gene id: 1298851:AXH83_RS03260
uniprot id: A0A0S3QSX1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1298851:AXH83 RS04210
gene id: 1298851:AXH83_RS04210
uniprot id: A0A0S3QTG4
names: Similarity
messages: Belongs to the ParB family.

1298851:AXH83 RS05075
gene id: 1298851:AXH83_RS05075
uniprot id: A0A0S3QTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1298851:AXH83 RS07500
gene id: 1298851:AXH83_RS07500
uniprot id: A0A0S3QV56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1298851:AXH83 RS02615
gene id: 1298851:AXH83_RS02615
uniprot id: A0A0S3QSJ2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1298851:AXH83 RS06495
gene id: 1298851:AXH83_RS06495
uniprot id: A0A0S3QUN4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1298851:AXH83 RS09360
gene id: 1298851:AXH83_RS09360
uniprot id: A0A0S3QW68
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1298851:AXH83 RS02265
gene id: 1298851:AXH83_RS02265
uniprot id: A0A0S3QSD2
names: Similarity
messages: Belongs to the sigma-54 factor family.

1298851:AXH83 RS02285
gene id: 1298851:AXH83_RS02285
uniprot id: A0A0S3QSI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS03080
gene id: 1298851:AXH83_RS03080
uniprot id: A0A0S3QSU8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1298851:AXH83 RS08160
gene id: 1298851:AXH83_RS08160
uniprot id: A0A0S3QVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1298851:AXH83 RS01575
gene id: 1298851:AXH83_RS01575
uniprot id: A0A0S3QS16
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1298851:AXH83 RS07805
gene id: 1298851:AXH83_RS07805
uniprot id: A0A0S3QVC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1298851:AXH83 RS03120
gene id: 1298851:AXH83_RS03120
uniprot id: A0A0S3QT00
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1298851:AXH83 RS07510
gene id: 1298851:AXH83_RS07510
uniprot id: A0A0S3QV78
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1298851:AXH83 RS01050
gene id: 1298851:AXH83_RS01050
uniprot id: A0A0S3QRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1298851:AXH83 RS00685
gene id: 1298851:AXH83_RS00685
uniprot id: A0A0S3QRH3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1298851:AXH83 RS09035
gene id: 1298851:AXH83_RS09035
uniprot id: A0A0S3QW04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1298851:AXH83 RS05680
gene id: 1298851:AXH83_RS05680
uniprot id: A0A0S3QU70
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1298851:AXH83 RS04490
gene id: 1298851:AXH83_RS04490
uniprot id: A0A0S3QTK5
names: Similarity
messages: Belongs to the UPF0047 family.

1298851:AXH83 RS02010
gene id: 1298851:AXH83_RS02010
uniprot id: A0A0S3QS83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1298851:AXH83 RS05340
gene id: 1298851:AXH83_RS05340
uniprot id: A0A0S3QU06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1298851:AXH83 RS07430
gene id: 1298851:AXH83_RS07430
uniprot id: A0A0S3QV71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1298851:AXH83 RS03615
gene id: 1298851:AXH83_RS03615
uniprot id: A0A0S3QT38
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1298851:AXH83 RS01410
gene id: 1298851:AXH83_RS01410
uniprot id: A0A0S3QS09
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.