1295382:K5607 RS13140
gene id: 1295382:K5607_RS13140
uniprot id: A0A8D5AHZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1295382:K5607 RS15375
gene id: 1295382:K5607_RS15375
uniprot id: A0A8D4VRI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1295382:K5607 RS04435
gene id: 1295382:K5607_RS04435
uniprot id: A0A8D5AIZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1295382:K5607 RS03145
gene id: 1295382:K5607_RS03145
uniprot id: A0A8D4VNX5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1295382:K5607 RS03375
gene id: 1295382:K5607_RS03375
uniprot id: A0A8D5AG61
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1295382:K5607 RS04060
gene id: 1295382:K5607_RS04060
uniprot id: A0A8D5ALJ4
names: Similarity
messages: Belongs to the peptidase A31 family.

1295382:K5607 RS01475
gene id: 1295382:K5607_RS01475
uniprot id: A0A8D4VNA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1295382:K5607 RS14535
gene id: 1295382:K5607_RS14535
uniprot id: A0A8D4VS12
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1295382:K5607 RS13055
gene id: 1295382:K5607_RS13055
uniprot id: A0A8D5AJ18
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1295382:K5607 RS06665
gene id: 1295382:K5607_RS06665
uniprot id: A0A8D5AM18
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1295382:K5607 RS15100
gene id: 1295382:K5607_RS15100
uniprot id: A0A8D5ALP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1295382:K5607 RS15165
gene id: 1295382:K5607_RS15165
uniprot id: A0A8D5AIB5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1295382:K5607 RS00035
gene id: 1295382:K5607_RS00035
uniprot id: A0A8D5AGN9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1295382:K5607 RS17120
gene id: 1295382:K5607_RS17120
uniprot id: A0A8D4VRE2
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1295382:K5607 RS15920
gene id: 1295382:K5607_RS15920
uniprot id: A0A8D4VSI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1295382:K5607 RS11870
gene id: 1295382:K5607_RS11870
uniprot id: A0A8D5AHQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1295382:K5607 RS16320
gene id: 1295382:K5607_RS16320
uniprot id: A0A8D4VTY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1295382:K5607 RS04085
gene id: 1295382:K5607_RS04085
uniprot id: A0A8D4VLU5
names: Similarity
messages: Belongs to the histone deacetylase family.

1295382:K5607 RS07350
gene id: 1295382:K5607_RS07350
uniprot id: A0A8D5AJI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1295382:K5607 RS04330
gene id: 1295382:K5607_RS04330
uniprot id: A0A8D4VN20
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1295382:K5607 RS00640
gene id: 1295382:K5607_RS00640
uniprot id: A0A8D4VMZ3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1295382:K5607 RS09375
gene id: 1295382:K5607_RS09375
uniprot id: A0A8D5AKK0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1295382:K5607 RS00080
gene id: 1295382:K5607_RS00080
uniprot id: A0A8D4VKG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1295382:K5607 RS03360
gene id: 1295382:K5607_RS03360
uniprot id: A0A8D4VPD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1295382:K5607 RS05400
gene id: 1295382:K5607_RS05400
uniprot id: A0A8D4VMX6
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1295382:K5607 RS10320
gene id: 1295382:K5607_RS10320
uniprot id: A0A8D4VQC5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1295382:K5607 RS15760
gene id: 1295382:K5607_RS15760
uniprot id: A0A8D4VQ82
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1295382:K5607 RS16745
gene id: 1295382:K5607_RS16745
uniprot id: A0A8D4VRS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1295382:K5607 RS09360
gene id: 1295382:K5607_RS09360
uniprot id: A0A8D5AH89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1295382:K5607 RS02005
gene id: 1295382:K5607_RS02005
uniprot id: A0A8D4VME4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1295382:K5607 RS14675
gene id: 1295382:K5607_RS14675
uniprot id: A0A8D4VRA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1295382:K5607 RS06435
gene id: 1295382:K5607_RS06435
uniprot id: A0A8D4VP49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1295382:K5607 RS13455
gene id: 1295382:K5607_RS13455
uniprot id: A0A8D5AI10
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1295382:K5607 RS06310
gene id: 1295382:K5607_RS06310
uniprot id: A0A8D4VQM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1295382:K5607 RS03635
gene id: 1295382:K5607_RS03635
uniprot id: A0A8D4VM94
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1295382:K5607 RS00115
gene id: 1295382:K5607_RS00115
uniprot id: A0A8D4VMR7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS05430
gene id: 1295382:K5607_RS05430
uniprot id: A0A8D5AGJ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1295382:K5607 RS03475
gene id: 1295382:K5607_RS03475
uniprot id: A0A8D4VLJ3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1295382:K5607 RS02315
gene id: 1295382:K5607_RS02315
uniprot id: A0A8D5AJA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1295382:K5607 RS03835
gene id: 1295382:K5607_RS03835
uniprot id: A0A8D5AJK2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1295382:K5607 RS00795
gene id: 1295382:K5607_RS00795
uniprot id: A0A8D5AFQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1295382:K5607 RS15995
gene id: 1295382:K5607_RS15995
uniprot id: A0A8D4VQA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS05195
gene id: 1295382:K5607_RS05195
uniprot id: A0A8D4VPR1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1295382:K5607 RS01880
gene id: 1295382:K5607_RS01880
uniprot id: A0A8D5AH03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1295382:K5607 RS03755
gene id: 1295382:K5607_RS03755
uniprot id: A0A8D5ALH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1295382:K5607 RS13155
gene id: 1295382:K5607_RS13155
uniprot id: A0A8D5ALC7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1295382:K5607 RS02095
gene id: 1295382:K5607_RS02095
uniprot id: A0A8D4VNI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1295382:K5607 RS10050
gene id: 1295382:K5607_RS10050
uniprot id: A0A8D5AK17
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1295382:K5607 RS03440
gene id: 1295382:K5607_RS03440
uniprot id: A0A8D5AHA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1295382:K5607 RS07305
gene id: 1295382:K5607_RS07305
uniprot id: A0A8D4VMY3
names: Similarity
messages: Belongs to the UPF0260 family.

1295382:K5607 RS00880
gene id: 1295382:K5607_RS00880
uniprot id: A0A8D5AKW8
names: Similarity
messages: Belongs to the UPF0234 family.

1295382:K5607 RS17685
gene id: 1295382:K5607_RS17685
uniprot id: A0A8D4VV71
names: Similarity
messages: Belongs to the LOG family.

1295382:K5607 RS17905
gene id: 1295382:K5607_RS17905
uniprot id: A0A8D4VTA3
names: Similarity
messages: Belongs to the fructosamine kinase family.

1295382:K5607 RS09245
gene id: 1295382:K5607_RS09245
uniprot id: A0A8D4VP47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1295382:K5607 RS13700
gene id: 1295382:K5607_RS13700
uniprot id: A0A8D5ALG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

1295382:K5607 RS06810
gene id: 1295382:K5607_RS06810
uniprot id: A0A8D5AJF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1295382:K5607 RS13845
gene id: 1295382:K5607_RS13845
uniprot id: A0A8D5ANH6
names: Similarity
messages: Belongs to the YoeB family.

1295382:K5607 RS15125
gene id: 1295382:K5607_RS15125
uniprot id: A0A8D4VR84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1295382:K5607 RS03445
gene id: 1295382:K5607_RS03445
uniprot id: A0A8D4VP24
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1295382:K5607 RS08645
gene id: 1295382:K5607_RS08645
uniprot id: A0A8D4VMT7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1295382:K5607 RS03045
gene id: 1295382:K5607_RS03045
uniprot id: A0A8D4VM03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1295382:K5607 RS07450
gene id: 1295382:K5607_RS07450
uniprot id: A0A8D4VMY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1295382:K5607 RS01375
gene id: 1295382:K5607_RS01375
uniprot id: A0A8D4VN91
names: Subcellular Location Annotation
messages: Membrane

1295382:K5607 RS11040
gene id: 1295382:K5607_RS11040
uniprot id: A0A8D5AHJ8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1295382:K5607 RS02055
gene id: 1295382:K5607_RS02055
uniprot id: A0A8D4VNH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1295382:K5607 RS18000
gene id: 1295382:K5607_RS18000
uniprot id: A0A8D4VLT9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1295382:K5607 RS06465
gene id: 1295382:K5607_RS06465
uniprot id: A0A8D4VM34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1295382:K5607 RS06995
gene id: 1295382:K5607_RS06995
uniprot id: A0A8D4VNI3
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1295382:K5607 RS03585
gene id: 1295382:K5607_RS03585
uniprot id: A0A8D4VP40
names: Subunit
messages: Monomer. Interacts with PqqE.

1295382:K5607 RS04250
gene id: 1295382:K5607_RS04250
uniprot id: A0A8D4VLB4
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1295382:K5607 RS10535
gene id: 1295382:K5607_RS10535
uniprot id: A0A8D4VRY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1295382:K5607 RS06440
gene id: 1295382:K5607_RS06440
uniprot id: A0A8D4VML2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1295382:K5607 RS17820
gene id: 1295382:K5607_RS17820
uniprot id: A0A8D4VSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1295382:K5607 RS09110
gene id: 1295382:K5607_RS09110
uniprot id: A0A8D4VRQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1295382:K5607 RS05640
gene id: 1295382:K5607_RS05640
uniprot id: A0A8D4VNJ5
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1295382:K5607 RS03915
gene id: 1295382:K5607_RS03915
uniprot id: A0A8D5AJK7
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1295382:K5607 RS05225
gene id: 1295382:K5607_RS05225
uniprot id: A0A8D4VM64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1295382:K5607 RS12045
gene id: 1295382:K5607_RS12045
uniprot id: A0A8D4VPM7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS07640
gene id: 1295382:K5607_RS07640
uniprot id: A0A8D4VQQ7
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1295382:K5607 RS06420
gene id: 1295382:K5607_RS06420
uniprot id: A0A8D5AJC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1295382:K5607 RS05525
gene id: 1295382:K5607_RS05525
uniprot id: A0A8D4VNT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1295382:K5607 RS01070
gene id: 1295382:K5607_RS01070
uniprot id: A0A8D4VKP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1295382:K5607 RS06565
gene id: 1295382:K5607_RS06565
uniprot id: A0A8D4VQA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1295382:K5607 RS06325
gene id: 1295382:K5607_RS06325
uniprot id: A0A8D5AGQ5
names: Similarity
messages: Belongs to the aspartokinase family.

1295382:K5607 RS08695
gene id: 1295382:K5607_RS08695
uniprot id: A0A8D4VNE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1295382:K5607 RS15400
gene id: 1295382:K5607_RS15400
uniprot id: A0A8D4VTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1295382:K5607 RS11680
gene id: 1295382:K5607_RS11680
uniprot id: A0A8D4VSD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1295382:K5607 RS17440
gene id: 1295382:K5607_RS17440
uniprot id: A0A8D4VS89
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1295382:K5607 RS04345
gene id: 1295382:K5607_RS04345
uniprot id: A0A8D4VPE4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1295382:K5607 RS05375
gene id: 1295382:K5607_RS05375
uniprot id: A0A8D4VNQ9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1295382:K5607 RS06870
gene id: 1295382:K5607_RS06870
uniprot id: A0A8D5AHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1295382:K5607 RS13400
gene id: 1295382:K5607_RS13400
uniprot id: A0A8D4VRN0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1295382:K5607 RS17300
gene id: 1295382:K5607_RS17300
uniprot id: A0A8D4VT29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1295382:K5607 RS11895
gene id: 1295382:K5607_RS11895
uniprot id: A0A8D4VPK2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1295382:K5607 RS17910
gene id: 1295382:K5607_RS17910
uniprot id: A0A8D4VVA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1295382:K5607 RS13180
gene id: 1295382:K5607_RS13180
uniprot id: A0A8D4VQL2
names: Similarity
messages: Belongs to the ArsC family.

1295382:K5607 RS12790
gene id: 1295382:K5607_RS12790
uniprot id: A0A8D5ALA4
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1295382:K5607 RS02060
gene id: 1295382:K5607_RS02060
uniprot id: A0A8D5AFY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1295382:K5607 RS04320
gene id: 1295382:K5607_RS04320
uniprot id: A0A8D4VMI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1295382:K5607 RS17665
gene id: 1295382:K5607_RS17665
uniprot id: A0A8D4VS46
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1295382:K5607 RS12255
gene id: 1295382:K5607_RS12255
uniprot id: A0A8D5AKH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1295382:K5607 RS05665
gene id: 1295382:K5607_RS05665
uniprot id: A0A8D5AJ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1295382:K5607 RS02670
gene id: 1295382:K5607_RS02670
uniprot id: A0A8D4VP39
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1295382:K5607 RS13375
gene id: 1295382:K5607_RS13375
uniprot id: A0A8D4VSY7
names: Similarity
messages: Belongs to the NifX/NifY family.

1295382:K5607 RS03690
gene id: 1295382:K5607_RS03690
uniprot id: A0A8D4VN21
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1295382:K5607 RS01850
gene id: 1295382:K5607_RS01850
uniprot id: A0A8D4VLG5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1295382:K5607 RS02680
gene id: 1295382:K5607_RS02680
uniprot id: A0A8D4VNR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1295382:K5607 RS01175
gene id: 1295382:K5607_RS01175
uniprot id: A0A8D4VLU3
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1295382:K5607 RS08655
gene id: 1295382:K5607_RS08655
uniprot id: A0A8D4VRJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1295382:K5607 RS00020
gene id: 1295382:K5607_RS00020
uniprot id: A0A8D4VJT8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1295382:K5607 RS16495
gene id: 1295382:K5607_RS16495
uniprot id: A0A8D5ALY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1295382:K5607 RS14350
gene id: 1295382:K5607_RS14350
uniprot id: A0A8D4VQH8
names: Similarity
messages: Belongs to the UPF0178 family.

1295382:K5607 RS15495
gene id: 1295382:K5607_RS15495
uniprot id: A0A8D5ALS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1295382:K5607 RS00010
gene id: 1295382:K5607_RS00010
uniprot id: A0A8D4VKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1295382:K5607 RS06175
gene id: 1295382:K5607_RS06175
uniprot id: A0A8D5AGP6
names: Similarity
messages: Belongs to the hemerythrin family.

1295382:K5607 RS00570
gene id: 1295382:K5607_RS00570
uniprot id: A0A8D5AI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1295382:K5607 RS05975
gene id: 1295382:K5607_RS05975
uniprot id: A0A8D4VMF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1295382:K5607 RS17805
gene id: 1295382:K5607_RS17805
uniprot id: A0A8D4VUU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1295382:K5607 RS15340
gene id: 1295382:K5607_RS15340
uniprot id: A0A8D4VSE3
names: Similarity
messages: Belongs to the Smg family.

1295382:K5607 RS15450
gene id: 1295382:K5607_RS15450
uniprot id: A0A8D4VRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1295382:K5607 RS17195
gene id: 1295382:K5607_RS17195
uniprot id: A0A8D4VUL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1295382:K5607 RS03435
gene id: 1295382:K5607_RS03435
uniprot id: A0A8D4VPE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1295382:K5607 RS14315
gene id: 1295382:K5607_RS14315
uniprot id: A0A8D5AJ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1295382:K5607 RS11235
gene id: 1295382:K5607_RS11235
uniprot id: A0A8D4VPW9
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1295382:K5607 RS00480
gene id: 1295382:K5607_RS00480
uniprot id: A0A8D5AGR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1295382:K5607 RS11570
gene id: 1295382:K5607_RS11570
uniprot id: A0A8D5AHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1295382:K5607 RS10750
gene id: 1295382:K5607_RS10750
uniprot id: A0A8D4VQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1295382:K5607 RS12200
gene id: 1295382:K5607_RS12200
uniprot id: A0A8D4VPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1295382:K5607 RS07770
gene id: 1295382:K5607_RS07770
uniprot id: A0A8D4VMI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1295382:K5607 RS07120
gene id: 1295382:K5607_RS07120
uniprot id: A0A8D5AM55
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1295382:K5607 RS02035
gene id: 1295382:K5607_RS02035
uniprot id: A0A8D4VKI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1295382:K5607 RS16655
gene id: 1295382:K5607_RS16655
uniprot id: A0A8D4VSW4
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

1295382:K5607 RS09635
gene id: 1295382:K5607_RS09635
uniprot id: A0A8D4VN59
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1295382:K5607 RS14215
gene id: 1295382:K5607_RS14215
uniprot id: A0A8D4VR39
names: Caution
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS05085
gene id: 1295382:K5607_RS05085
uniprot id: A0A8D4VMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1295382:K5607 RS12555
gene id: 1295382:K5607_RS12555
uniprot id: A0A8D5AKJ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1295382:K5607 RS15880
gene id: 1295382:K5607_RS15880
uniprot id: A0A8D5ALU8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1295382:K5607 RS07195
gene id: 1295382:K5607_RS07195
uniprot id: A0A8D5AM60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1295382:K5607 RS11295
gene id: 1295382:K5607_RS11295
uniprot id: A0A8D4VPC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1295382:K5607 RS02115
gene id: 1295382:K5607_RS02115
uniprot id: A0A8D4VKI9
names: Similarity
messages: Belongs to the HisA/HisF family.

1295382:K5607 RS10820
gene id: 1295382:K5607_RS10820
uniprot id: A0A8D5AKV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1295382:K5607 RS11320
gene id: 1295382:K5607_RS11320
uniprot id: A0A8D4VNS3
names: Similarity
messages: Belongs to the UPF0047 family.

1295382:K5607 RS09405
gene id: 1295382:K5607_RS09405
uniprot id: A0A8D4VPC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1295382:K5607 RS04530
gene id: 1295382:K5607_RS04530
uniprot id: A0A8D4VLY9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1295382:K5607 RS06950
gene id: 1295382:K5607_RS06950
uniprot id: A0A8D4VQG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1295382:K5607 RS01190
gene id: 1295382:K5607_RS01190
uniprot id: A0A8D4VN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1295382:K5607 RS11440
gene id: 1295382:K5607_RS11440
uniprot id: A0A8D4VQY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1295382:K5607 RS04075
gene id: 1295382:K5607_RS04075
uniprot id: A0A8D4VLS3
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

1295382:K5607 RS12610
gene id: 1295382:K5607_RS12610
uniprot id: A0A8D4VT64
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1295382:K5607 RS00230
gene id: 1295382:K5607_RS00230
uniprot id: A0A8D4VKI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1295382:K5607 RS01980
gene id: 1295382:K5607_RS01980
uniprot id: A0A8D4VNG4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1295382:K5607 RS03180
gene id: 1295382:K5607_RS03180
uniprot id: A0A8D4VNX9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1295382:K5607 RS09235
gene id: 1295382:K5607_RS09235
uniprot id: A0A8D4VRE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1295382:K5607 RS02530
gene id: 1295382:K5607_RS02530
uniprot id: A0A8D5AG12
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1295382:K5607 RS02100
gene id: 1295382:K5607_RS02100
uniprot id: A0A8D4VL56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1295382:K5607 RS11575
gene id: 1295382:K5607_RS11575
uniprot id: A0A8D5AKC3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1295382:K5607 RS06330
gene id: 1295382:K5607_RS06330
uniprot id: A0A8D5AJC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1295382:K5607 RS07245
gene id: 1295382:K5607_RS07245
uniprot id: A0A8D4VMC4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1295382:K5607 RS11325
gene id: 1295382:K5607_RS11325
uniprot id: A0A8D4VQR5
names: Subcellular Location Annotation
messages: Cytoplasm

1295382:K5607 RS15210
gene id: 1295382:K5607_RS15210
uniprot id: A0A8D4VRH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1295382:K5607 RS09800
gene id: 1295382:K5607_RS09800
uniprot id: A0A8D4VQ51
names: Similarity
messages: Belongs to the fabD family.

1295382:K5607 RS02445
gene id: 1295382:K5607_RS02445
uniprot id: A0A8D5AH36
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1295382:K5607 RS11725
gene id: 1295382:K5607_RS11725
uniprot id: A0A8D5AHP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1295382:K5607 RS09695
gene id: 1295382:K5607_RS09695
uniprot id: A0A8D4VQA3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1295382:K5607 RS16095
gene id: 1295382:K5607_RS16095
uniprot id: A0A8D5AIH6
names: Similarity
messages: Belongs to the CutA family.

1295382:K5607 RS14245
gene id: 1295382:K5607_RS14245
uniprot id: A0A8D5AI59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1295382:K5607 RS08240
gene id: 1295382:K5607_RS08240
uniprot id: A0A8D4VNY2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS02040
gene id: 1295382:K5607_RS02040
uniprot id: A0A8D4VM54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1295382:K5607 RS15940
gene id: 1295382:K5607_RS15940
uniprot id: A0A8D5AIG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1295382:K5607 RS11580
gene id: 1295382:K5607_RS11580
uniprot id: A0A8D5AN21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1295382:K5607 RS17445
gene id: 1295382:K5607_RS17445
uniprot id: A0A8D4VQS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1295382:K5607 RS08375
gene id: 1295382:K5607_RS08375
uniprot id: A0A8D4VR22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1295382:K5607 RS06485
gene id: 1295382:K5607_RS06485
uniprot id: A0A8D4VQ97
names: Subcellular Location Annotation
messages: Membrane

1295382:K5607 RS12670
gene id: 1295382:K5607_RS12670
uniprot id: A0A8D4VQJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1295382:K5607 RS10375
gene id: 1295382:K5607_RS10375
uniprot id: A0A8D4VP09
names: Subcellular Location Annotation
messages: Membrane

1295382:K5607 RS00040
gene id: 1295382:K5607_RS00040
uniprot id: A0A8D4VMQ9
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1295382:K5607 RS10765
gene id: 1295382:K5607_RS10765
uniprot id: A0A8D4VP58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1295382:K5607 RS14160
gene id: 1295382:K5607_RS14160
uniprot id: A0A8D5AI54
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1295382:K5607 RS09090
gene id: 1295382:K5607_RS09090
uniprot id: A0A8D4VP26
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1295382:K5607 RS16630
gene id: 1295382:K5607_RS16630
uniprot id: A0A8D5AIL0
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1295382:K5607 RS02080
gene id: 1295382:K5607_RS02080
uniprot id: A0A8D4VMF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1295382:K5607 RS07065
gene id: 1295382:K5607_RS07065
uniprot id: A0A8D4VMV4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1295382:K5607 RS01125
gene id: 1295382:K5607_RS01125
uniprot id: A0A8D5AID2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1295382:K5607 RS10665
gene id: 1295382:K5607_RS10665
uniprot id: A0A8D5AK62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1295382:K5607 RS03895
gene id: 1295382:K5607_RS03895
uniprot id: A0A8D4VP83
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1295382:K5607 RS03580
gene id: 1295382:K5607_RS03580
uniprot id: A0A8D5AHB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1295382:K5607 RS10830
gene id: 1295382:K5607_RS10830
uniprot id: A0A8D4VP69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1295382:K5607 RS01485
gene id: 1295382:K5607_RS01485
uniprot id: A0A8D4VLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1295382:K5607 RS02565
gene id: 1295382:K5607_RS02565
uniprot id: A0A8D4VLB1
names: Similarity
messages: Belongs to the hemerythrin family.

1295382:K5607 RS16870
gene id: 1295382:K5607_RS16870
uniprot id: A0A8D5AP39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS10775
gene id: 1295382:K5607_RS10775
uniprot id: A0A8D4VPU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1295382:K5607 RS05310
gene id: 1295382:K5607_RS05310
uniprot id: A0A8D4VPS4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1295382:K5607 RS12865
gene id: 1295382:K5607_RS12865
uniprot id: A0A8D4VPZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1295382:K5607 RS03605
gene id: 1295382:K5607_RS03605
uniprot id: A0A8D5ALG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1295382:K5607 RS15405
gene id: 1295382:K5607_RS15405
uniprot id: A0A8D5AID1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1295382:K5607 RS16855
gene id: 1295382:K5607_RS16855
uniprot id: A0A8D4VU50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1295382:K5607 RS11695
gene id: 1295382:K5607_RS11695
uniprot id: A0A8D4VQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1295382:K5607 RS16235
gene id: 1295382:K5607_RS16235
uniprot id: A0A8D5AJM5
names: Similarity
messages: Belongs to the RNase T2 family.

1295382:K5607 RS17240
gene id: 1295382:K5607_RS17240
uniprot id: A0A8D4VU94
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1295382:K5607 RS11740
gene id: 1295382:K5607_RS11740
uniprot id: A0A8D5AL22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1295382:K5607 RS07475
gene id: 1295382:K5607_RS07475
uniprot id: A0A8D4VMF1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1295382:K5607 RS06900
gene id: 1295382:K5607_RS06900
uniprot id: A0A8D4VPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1295382:K5607 RS12825
gene id: 1295382:K5607_RS12825
uniprot id: A0A8D4VRD9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1295382:K5607 RS03120
gene id: 1295382:K5607_RS03120
uniprot id: A0A8D4VM17
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1295382:K5607 RS10520
gene id: 1295382:K5607_RS10520
uniprot id: A0A8D5AKS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS13550
gene id: 1295382:K5607_RS13550
uniprot id: A0A8D5ALF2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1295382:K5607 RS02025
gene id: 1295382:K5607_RS02025
uniprot id: A0A8D4VLI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1295382:K5607 RS05315
gene id: 1295382:K5607_RS05315
uniprot id: A0A8D4VM89
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1295382:K5607 RS04705
gene id: 1295382:K5607_RS04705
uniprot id: A0A8D4VLI9
names: Similarity
messages: Belongs to the TelA family.

1295382:K5607 RS02660
gene id: 1295382:K5607_RS02660
uniprot id: A0A8D4VKQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1295382:K5607 RS16155
gene id: 1295382:K5607_RS16155
uniprot id: A0A8D4VUK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1295382:K5607 RS04415
gene id: 1295382:K5607_RS04415
uniprot id: A0A8D4VPT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1295382:K5607 RS02065
gene id: 1295382:K5607_RS02065
uniprot id: A0A8D5AIJ2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1295382:K5607 RS10970
gene id: 1295382:K5607_RS10970
uniprot id: A0A8D5AMX8
names: Similarity
messages: Belongs to the P(II) protein family.

1295382:K5607 RS02020
gene id: 1295382:K5607_RS02020
uniprot id: A0A8D4VL48
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1295382:K5607 RS04365
gene id: 1295382:K5607_RS04365
uniprot id: A0A8D5AJN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1295382:K5607 RS04180
gene id: 1295382:K5607_RS04180
uniprot id: A0A8D4VPQ4
names: Similarity
messages: Belongs to the GbsR family.

1295382:K5607 RS02650
gene id: 1295382:K5607_RS02650
uniprot id: A0A8D4VLQ8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1295382:K5607 RS04305
gene id: 1295382:K5607_RS04305
uniprot id: A0A8D4VPD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1295382:K5607 RS04565
gene id: 1295382:K5607_RS04565
uniprot id: A0A8D4VPW8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1295382:K5607 RS07060
gene id: 1295382:K5607_RS07060
uniprot id: A0A8D4VQH6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1295382:K5607 RS08465
gene id: 1295382:K5607_RS08465
uniprot id: A0A8D4VNU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1295382:K5607 RS16330
gene id: 1295382:K5607_RS16330
uniprot id: A0A8D5AL87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1295382:K5607 RS03465
gene id: 1295382:K5607_RS03465
uniprot id: A0A8D5AJH6
names: Similarity
messages: Belongs to the MEMO1 family.

1295382:K5607 RS03600
gene id: 1295382:K5607_RS03600
uniprot id: A0A8D5AIU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

1295382:K5607 RS13990
gene id: 1295382:K5607_RS13990
uniprot id: A0A8D5AKT2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1295382:K5607 RS01925
gene id: 1295382:K5607_RS01925
uniprot id: A0A8D5AJ76
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1295382:K5607 RS11290
gene id: 1295382:K5607_RS11290
uniprot id: A0A8D4VPC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1295382:K5607 RS04020
gene id: 1295382:K5607_RS04020
uniprot id: A0A8D4VME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1295382:K5607 RS09470
gene id: 1295382:K5607_RS09470
uniprot id: A0A8D4VNN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1295382:K5607 RS13065
gene id: 1295382:K5607_RS13065
uniprot id: A0A8D5AHY7
names: Similarity
messages: Belongs to the YfgM family.

1295382:K5607 RS17265
gene id: 1295382:K5607_RS17265
uniprot id: A0A8D4VT46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1295382:K5607 RS02220
gene id: 1295382:K5607_RS02220
uniprot id: A0A8D4VNJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1295382:K5607 RS07280
gene id: 1295382:K5607_RS07280
uniprot id: A0A8D5AM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1295382:K5607 RS15660
gene id: 1295382:K5607_RS15660
uniprot id: A0A8D4VR02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1295382:K5607 RS03130
gene id: 1295382:K5607_RS03130
uniprot id: A0A8D4VMJ5
names: Similarity
messages: Belongs to the YkuD family.

1295382:K5607 RS10690
gene id: 1295382:K5607_RS10690
uniprot id: A0A8D4VS06
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1295382:K5607 RS14655
gene id: 1295382:K5607_RS14655
uniprot id: A0A8D4VQL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1295382:K5607 RS00610
gene id: 1295382:K5607_RS00610
uniprot id: A0A8D4VL37
names: Similarity
messages: Belongs to the TrpC family.

1295382:K5607 RS08730
gene id: 1295382:K5607_RS08730
uniprot id: A0A8D4VRK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1295382:K5607 RS01975
gene id: 1295382:K5607_RS01975
uniprot id: A0A8D5AH07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1295382:K5607 RS07215
gene id: 1295382:K5607_RS07215
uniprot id: A0A8D4VPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1295382:K5607 RS05445
gene id: 1295382:K5607_RS05445
uniprot id: A0A8D5AJV7
names: Similarity
messages: Belongs to the YkuD family.

1295382:K5607 RS01920
gene id: 1295382:K5607_RS01920
uniprot id: A0A8D5AL36
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1295382:K5607 RS00155
gene id: 1295382:K5607_RS00155
uniprot id: A0A8D4VKH5
names: Similarity
messages: Belongs to the GSP E family.

1295382:K5607 RS08665
gene id: 1295382:K5607_RS08665
uniprot id: A0A8D4VR47
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1295382:K5607 RS06875
gene id: 1295382:K5607_RS06875
uniprot id: A0A8D4VQE6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS15005
gene id: 1295382:K5607_RS15005
uniprot id: A0A8D5AL03
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1295382:K5607 RS00635
gene id: 1295382:K5607_RS00635
uniprot id: A0A8D5AGS8
names: Similarity
messages: Belongs to the UPF0102 family.

1295382:K5607 RS02370
gene id: 1295382:K5607_RS02370
uniprot id: A0A8D4VNL6
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1295382:K5607 RS08800
gene id: 1295382:K5607_RS08800
uniprot id: A0A8D4VPR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1295382:K5607 RS02460
gene id: 1295382:K5607_RS02460
uniprot id: A0A8D5AIL5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1295382:K5607 RS16080
gene id: 1295382:K5607_RS16080
uniprot id: A0A8D4VUJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1295382:K5607 RS08225
gene id: 1295382:K5607_RS08225
uniprot id: A0A8D4VR03
names: Subcellular Location Annotation
messages: Membrane

1295382:K5607 RS17125
gene id: 1295382:K5607_RS17125
uniprot id: A0A8D4VRX1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1295382:K5607 RS03650
gene id: 1295382:K5607_RS03650
uniprot id: A0A8D4VPH7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1295382:K5607 RS01875
gene id: 1295382:K5607_RS01875
uniprot id: A0A8D4VNT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1295382:K5607 RS04350
gene id: 1295382:K5607_RS04350
uniprot id: A0A8D5AGC3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1295382:K5607 RS09335
gene id: 1295382:K5607_RS09335
uniprot id: A0A8D4VN22
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS10000
gene id: 1295382:K5607_RS10000
uniprot id: A0A8D4VRQ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1295382:K5607 RS07155
gene id: 1295382:K5607_RS07155
uniprot id: A0A8D4VND5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1295382:K5607 RS14325
gene id: 1295382:K5607_RS14325
uniprot id: A0A8D5AI62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1295382:K5607 RS10440
gene id: 1295382:K5607_RS10440
uniprot id: A0A8D4VP18
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1295382:K5607 RS03315
gene id: 1295382:K5607_RS03315
uniprot id: A0A8D5AJG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1295382:K5607 RS16640
gene id: 1295382:K5607_RS16640
uniprot id: A0A8D5ALA5
names: Subcellular Location Annotation
messages: Nucleus

1295382:K5607 RS14475
gene id: 1295382:K5607_RS14475
uniprot id: A0A8D4VTB8
names: Subcellular Location Annotation
messages: Membrane

1295382:K5607 RS03470
gene id: 1295382:K5607_RS03470
uniprot id: A0A8D4VMY8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1295382:K5607 RS14310
gene id: 1295382:K5607_RS14310
uniprot id: A0A8D4VTU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1295382:K5607 RS13925
gene id: 1295382:K5607_RS13925
uniprot id: A0A8D5ALH5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1295382:K5607 RS12880
gene id: 1295382:K5607_RS12880
uniprot id: A0A8D4VQH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1295382:K5607 RS14610
gene id: 1295382:K5607_RS14610
uniprot id: A0A8D4VS22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1295382:K5607 RS08335
gene id: 1295382:K5607_RS08335
uniprot id: A0A8D5AI66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1295382:K5607 RS01260
gene id: 1295382:K5607_RS01260
uniprot id: A0A8D5AGW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1295382:K5607 RS03395
gene id: 1295382:K5607_RS03395
uniprot id: A0A8D4VMX9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1295382:K5607 RS12295
gene id: 1295382:K5607_RS12295
uniprot id: A0A8D4VQE5
names: Similarity
messages: Belongs to the MlaA family.

1295382:K5607 RS08405
gene id: 1295382:K5607_RS08405
uniprot id: A0A8D4VRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1295382:K5607 RS16865
gene id: 1295382:K5607_RS16865
uniprot id: A0A8D5ALC1
names: Similarity
messages: Belongs to the thioredoxin family.

1295382:K5607 RS10695
gene id: 1295382:K5607_RS10695
uniprot id: A0A8D4VP48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1295382:K5607 RS15070
gene id: 1295382:K5607_RS15070
uniprot id: A0A8D4VU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1295382:K5607 RS13615
gene id: 1295382:K5607_RS13615
uniprot id: A0A8D5AKQ7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1295382:K5607 RS11310
gene id: 1295382:K5607_RS11310
uniprot id: A0A8D4VPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1295382:K5607 RS00465
gene id: 1295382:K5607_RS00465
uniprot id: A0A8D4VJZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1295382:K5607 RS16395
gene id: 1295382:K5607_RS16395
uniprot id: A0A8D4VTZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1295382:K5607 RS10810
gene id: 1295382:K5607_RS10810
uniprot id: A0A8D5AK72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1295382:K5607 RS12955
gene id: 1295382:K5607_RS12955
uniprot id: A0A8D4VQI3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1295382:K5607 RS13260
gene id: 1295382:K5607_RS13260
uniprot id: A0A8D4VQR9
names: Similarity
messages: Belongs to the Gfa family.

1295382:K5607 RS04400
gene id: 1295382:K5607_RS04400
uniprot id: A0A8D4VMJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1295382:K5607 RS15225
gene id: 1295382:K5607_RS15225
uniprot id: A0A8D4VU77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1295382:K5607 RS13555
gene id: 1295382:K5607_RS13555
uniprot id: A0A8D4VRQ0
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

1295382:K5607 RS01115
gene id: 1295382:K5607_RS01115
uniprot id: A0A8D4VN52
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1295382:K5607 RS09370
gene id: 1295382:K5607_RS09370
uniprot id: A0A8D5AMM0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1295382:K5607 RS01915
gene id: 1295382:K5607_RS01915
uniprot id: A0A8D5AII2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS14105
gene id: 1295382:K5607_RS14105
uniprot id: A0A8D4VRX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1295382:K5607 RS06920
gene id: 1295382:K5607_RS06920
uniprot id: A0A8D4VNA7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1295382:K5607 RS14380
gene id: 1295382:K5607_RS14380
uniprot id: A0A8D4VRZ2
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1295382:K5607 RS04040
gene id: 1295382:K5607_RS04040
uniprot id: A0A8D5AHD9
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1295382:K5607 RS12290
gene id: 1295382:K5607_RS12290
uniprot id: A0A8D4VQA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1295382:K5607 RS16430
gene id: 1295382:K5607_RS16430
uniprot id: A0A8D4VU93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1295382:K5607 RS06540
gene id: 1295382:K5607_RS06540
uniprot id: A0A8D4VM42
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1295382:K5607 RS17570
gene id: 1295382:K5607_RS17570
uniprot id: A0A8D4VT79
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1295382:K5607 RS11500
gene id: 1295382:K5607_RS11500
uniprot id: A0A8D5AKB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1295382:K5607 RS14180
gene id: 1295382:K5607_RS14180
uniprot id: A0A8D5ALI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1295382:K5607 RS12945
gene id: 1295382:K5607_RS12945
uniprot id: A0A8D4VSX6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1295382:K5607 RS00085
gene id: 1295382:K5607_RS00085
uniprot id: A0A8D4VKU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1295382:K5607 RS09940
gene id: 1295382:K5607_RS09940
uniprot id: A0A8D4VPI8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1295382:K5607 RS13705
gene id: 1295382:K5607_RS13705
uniprot id: A0A8D4VRR9
names: Similarity
messages: Belongs to the NifZ family.

1295382:K5607 RS08260
gene id: 1295382:K5607_RS08260
uniprot id: A0A8D5AI60
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1295382:K5607 RS15215
gene id: 1295382:K5607_RS15215
uniprot id: A0A8D4VQ22
names: Subcellular Location Annotation
names: Subunit
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane

1295382:K5607 RS00470
gene id: 1295382:K5607_RS00470
uniprot id: A0A8D4VLK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1295382:K5607 RS03090
gene id: 1295382:K5607_RS03090
uniprot id: A0A8D5AJF0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1295382:K5607 RS01250
gene id: 1295382:K5607_RS01250
uniprot id: A0A8D4VLV3
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1295382:K5607 RS01320
gene id: 1295382:K5607_RS01320
uniprot id: A0A8D4VKA0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS13130
gene id: 1295382:K5607_RS13130
uniprot id: A0A8D5AJ22
names: Similarity
messages: Belongs to the CcdB toxin family.

1295382:K5607 RS02015
gene id: 1295382:K5607_RS02015
uniprot id: A0A8D4VNH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1295382:K5607 RS00205
gene id: 1295382:K5607_RS00205
uniprot id: A0A8D5AKR9
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1295382:K5607 RS13085
gene id: 1295382:K5607_RS13085
uniprot id: A0A8D4VRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1295382:K5607 RS05205
gene id: 1295382:K5607_RS05205
uniprot id: A0A8D5AJ49
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1295382:K5607 RS17245
gene id: 1295382:K5607_RS17245
uniprot id: A0A8D5AIQ2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1295382:K5607 RS00280
gene id: 1295382:K5607_RS00280
uniprot id: A0A8D5AIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1295382:K5607 RS09105
gene id: 1295382:K5607_RS09105
uniprot id: A0A8D4VPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1295382:K5607 RS12820
gene id: 1295382:K5607_RS12820
uniprot id: A0A8D4VPA9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1295382:K5607 RS06460
gene id: 1295382:K5607_RS06460
uniprot id: A0A8D4VNB3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1295382:K5607 RS05515
gene id: 1295382:K5607_RS05515
uniprot id: A0A8D5ALU4
names: Similarity
messages: Belongs to the DsrF/TusC family.

1295382:K5607 RS00665
gene id: 1295382:K5607_RS00665
uniprot id: A0A8D4VLW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1295382:K5607 RS13090
gene id: 1295382:K5607_RS13090
uniprot id: A0A8D4VQ20
names: Similarity
messages: Belongs to the HesB/IscA family.

1295382:K5607 RS07320
gene id: 1295382:K5607_RS07320
uniprot id: A0A8D4VMD3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1295382:K5607 RS12160
gene id: 1295382:K5607_RS12160
uniprot id: A0A8D4VSY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1295382:K5607 RS09200
gene id: 1295382:K5607_RS09200
uniprot id: A0A8D4VRC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1295382:K5607 RS14385
gene id: 1295382:K5607_RS14385
uniprot id: A0A8D4VTW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1295382:K5607 RS00070
gene id: 1295382:K5607_RS00070
uniprot id: A0A8D4VKC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1295382:K5607 RS01760
gene id: 1295382:K5607_RS01760
uniprot id: A0A8D4VKX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS03040
gene id: 1295382:K5607_RS03040
uniprot id: A0A8D4VLV0
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1295382:K5607 RS10380
gene id: 1295382:K5607_RS10380
uniprot id: A0A8D4VPK1
names: Subcellular Location Annotation
messages: Membrane

1295382:K5607 RS16705
gene id: 1295382:K5607_RS16705
uniprot id: A0A8D5AIL4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1295382:K5607 RS08400
gene id: 1295382:K5607_RS08400
uniprot id: A0A8D4VPL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1295382:K5607 RS08875
gene id: 1295382:K5607_RS08875
uniprot id: A0A8D4VPS2
names: Similarity
messages: Belongs to the globin family.

1295382:K5607 RS02535
gene id: 1295382:K5607_RS02535
uniprot id: A0A8D5AIM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1295382:K5607 RS05630
gene id: 1295382:K5607_RS05630
uniprot id: A0A8D4VN06
names: Similarity
messages: Belongs to the type III secretion exporter family.

1295382:K5607 RS09685
gene id: 1295382:K5607_RS09685
uniprot id: A0A8D5AMP1
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1295382:K5607 RS02075
gene id: 1295382:K5607_RS02075
uniprot id: A0A8D5AJ85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1295382:K5607 RS05930
gene id: 1295382:K5607_RS05930
uniprot id: A0A8D4VLW9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1295382:K5607 RS00410
gene id: 1295382:K5607_RS00410
uniprot id: A0A8D4VMW1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1295382:K5607 RS00025
gene id: 1295382:K5607_RS00025
uniprot id: A0A8D4VLE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1295382:K5607 RS04295
gene id: 1295382:K5607_RS04295
uniprot id: A0A8D4VNB5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1295382:K5607 RS04420
gene id: 1295382:K5607_RS04420
uniprot id: A0A8D5AHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1295382:K5607 RS08760
gene id: 1295382:K5607_RS08760
uniprot id: A0A8D5AKG4
names: Caution
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS11705
gene id: 1295382:K5607_RS11705
uniprot id: A0A8D4VQX0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1295382:K5607 RS04335
gene id: 1295382:K5607_RS04335
uniprot id: A0A8D4VPS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1295382:K5607 RS15955
gene id: 1295382:K5607_RS15955
uniprot id: A0A8D5ANW8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1295382:K5607 RS14695
gene id: 1295382:K5607_RS14695
uniprot id: A0A8D5AJC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1295382:K5607 RS03890
gene id: 1295382:K5607_RS03890
uniprot id: A0A8D5AHC9
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

1295382:K5607 RS07820
gene id: 1295382:K5607_RS07820
uniprot id: A0A8D4VPM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1295382:K5607 RS02050
gene id: 1295382:K5607_RS02050
uniprot id: A0A8D5AH11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1295382:K5607 RS04410
gene id: 1295382:K5607_RS04410
uniprot id: A0A8D4VN31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1295382:K5607 RS17840
gene id: 1295382:K5607_RS17840
uniprot id: A0A8D5AJX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1295382:K5607 RS04150
gene id: 1295382:K5607_RS04150
uniprot id: A0A8D4VPB8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1295382:K5607 RS15795
gene id: 1295382:K5607_RS15795
uniprot id: A0A8D5ANV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methanol dehydrogenase subunit 2 family.
messages: Catalyzes the oxidation of primary alcohols including methanol.
messages: Heterotetramer composed of 2 alpha and 2 beta subunits.

1295382:K5607 RS12810
gene id: 1295382:K5607_RS12810
uniprot id: A0A8D4VQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1295382:K5607 RS02045
gene id: 1295382:K5607_RS02045
uniprot id: A0A8D4VNW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1295382:K5607 RS08270
gene id: 1295382:K5607_RS08270
uniprot id: A0A8D5AH23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1295382:K5607 RS10640
gene id: 1295382:K5607_RS10640
uniprot id: A0A8D4VQG4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1295382:K5607 RS14260
gene id: 1295382:K5607_RS14260
uniprot id: A0A8D5ALJ3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1295382:K5607 RS02230
gene id: 1295382:K5607_RS02230
uniprot id: A0A8D5AIK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1295382:K5607 RS15270
gene id: 1295382:K5607_RS15270
uniprot id: A0A8D4VQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1295382:K5607 RS07680
gene id: 1295382:K5607_RS07680
uniprot id: A0A8D4VN25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1295382:K5607 RS12150
gene id: 1295382:K5607_RS12150
uniprot id: A0A8D4VP17
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

1295382:K5607 RS08680
gene id: 1295382:K5607_RS08680
uniprot id: A0A8D5AMH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1295382:K5607 RS15960
gene id: 1295382:K5607_RS15960
uniprot id: A0A8D5ALV3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1295382:K5607 RS11625
gene id: 1295382:K5607_RS11625
uniprot id: A0A8D4VQW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1295382:K5607 RS14565
gene id: 1295382:K5607_RS14565
uniprot id: A0A8D5ANM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1295382:K5607 RS02010
gene id: 1295382:K5607_RS02010
uniprot id: A0A8D4VL02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1295382:K5607 RS01935
gene id: 1295382:K5607_RS01935
uniprot id: A0A8D4VKZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1295382:K5607 RS15250
gene id: 1295382:K5607_RS15250
uniprot id: A0A8D5ANS2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1295382:K5607 RS02000
gene id: 1295382:K5607_RS02000
uniprot id: A0A8D5AJ80
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1295382:K5607 RS12330
gene id: 1295382:K5607_RS12330
uniprot id: A0A8D5AKH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS02105
gene id: 1295382:K5607_RS02105
uniprot id: A0A8D4VLJ4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1295382:K5607 RS13290
gene id: 1295382:K5607_RS13290
uniprot id: A0A8D5AI01
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1295382:K5607 RS02860
gene id: 1295382:K5607_RS02860
uniprot id: A0A8D4VMQ5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1295382:K5607 RS03625
gene id: 1295382:K5607_RS03625
uniprot id: A0A8D4VP44
names: Similarity
messages: Belongs to the YkuD family.

1295382:K5607 RS15115
gene id: 1295382:K5607_RS15115
uniprot id: A0A8D4VTR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1295382:K5607 RS05510
gene id: 1295382:K5607_RS05510
uniprot id: A0A8D5AJ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1295382:K5607 RS01955
gene id: 1295382:K5607_RS01955
uniprot id: A0A8D4VLK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1295382:K5607 RS11475
gene id: 1295382:K5607_RS11475
uniprot id: A0A8D4VQU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS10900
gene id: 1295382:K5607_RS10900
uniprot id: A0A8D5AKV5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS16175
gene id: 1295382:K5607_RS16175
uniprot id: A0A8D5AL76
names: Subcellular Location Annotation
messages: Membrane

1295382:K5607 RS09365
gene id: 1295382:K5607_RS09365
uniprot id: A0A8D5AJW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1295382:K5607 RS09175
gene id: 1295382:K5607_RS09175
uniprot id: A0A8D4VP92
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1295382:K5607 RS10030
gene id: 1295382:K5607_RS10030
uniprot id: A0A8D4VS42
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1295382:K5607 RS17790
gene id: 1295382:K5607_RS17790
uniprot id: A0A8D5AM71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1295382:K5607 RS14330
gene id: 1295382:K5607_RS14330
uniprot id: A0A8D5AKV4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1295382:K5607 RS13425
gene id: 1295382:K5607_RS13425
uniprot id: A0A8D4VQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1295382:K5607 RS02170
gene id: 1295382:K5607_RS02170
uniprot id: A0A8D4VNJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1295382:K5607 RS02030
gene id: 1295382:K5607_RS02030
uniprot id: A0A8D4VLL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1295382:K5607 RS16050
gene id: 1295382:K5607_RS16050
uniprot id: A0A8D4VU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1295382:K5607 RS03965
gene id: 1295382:K5607_RS03965
uniprot id: A0A8D5AHD4
names: Similarity
messages: Belongs to the HupF/HypC family.

1295382:K5607 RS08385
gene id: 1295382:K5607_RS08385
uniprot id: A0A8D4VNU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1295382:K5607 RS05750
gene id: 1295382:K5607_RS05750
uniprot id: A0A8D5AJX6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1295382:K5607 RS03070
gene id: 1295382:K5607_RS03070
uniprot id: A0A8D4VNW3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1295382:K5607 RS01825
gene id: 1295382:K5607_RS01825
uniprot id: A0A8D5AJ72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS17870
gene id: 1295382:K5607_RS17870
uniprot id: A0A8D4VTC3
names: Similarity
messages: Belongs to the MotB family.

1295382:K5607 RS09150
gene id: 1295382:K5607_RS09150
uniprot id: A0A8D4VQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1295382:K5607 RS00165
gene id: 1295382:K5607_RS00165
uniprot id: A0A8D4VKX8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1295382:K5607 RS15415
gene id: 1295382:K5607_RS15415
uniprot id: A0A8D5ANT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1295382:K5607 RS16560
gene id: 1295382:K5607_RS16560
uniprot id: A0A8D5ALA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS00270
gene id: 1295382:K5607_RS00270
uniprot id: A0A8D5AI78
names: Similarity
messages: Belongs to the YoeB family.

1295382:K5607 RS13855
gene id: 1295382:K5607_RS13855
uniprot id: A0A8D4VRU1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1295382:K5607 RS06960
gene id: 1295382:K5607_RS06960
uniprot id: A0A8D5AJG0
names: Subcellular Location Annotation
messages: Membrane

1295382:K5607 RS02555
gene id: 1295382:K5607_RS02555
uniprot id: A0A8D4VL74
names: Similarity
messages: Belongs to the HSP15 family.

1295382:K5607 RS01470
gene id: 1295382:K5607_RS01470
uniprot id: A0A8D4VKT8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1295382:K5607 RS09310
gene id: 1295382:K5607_RS09310
uniprot id: A0A8D4VRF6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1295382:K5607 RS17655
gene id: 1295382:K5607_RS17655
uniprot id: A0A8D4VUS2
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1295382:K5607 RS05565
gene id: 1295382:K5607_RS05565
uniprot id: A0A8D4VQB3
names: Similarity
messages: Belongs to the UPF0434 family.

1295382:K5607 RS10825
gene id: 1295382:K5607_RS10825
uniprot id: A0A8D4VQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1295382:K5607 RS05380
gene id: 1295382:K5607_RS05380
uniprot id: A0A8D4VM82
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1295382:K5607 RS17115
gene id: 1295382:K5607_RS17115
uniprot id: A0A8D4VUJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1295382:K5607 RS06550
gene id: 1295382:K5607_RS06550
uniprot id: A0A8D4VQQ5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1295382:K5607 RS02845
gene id: 1295382:K5607_RS02845
uniprot id: A0A8D5AIP0
names: Similarity
messages: Belongs to the MoaD family.

1295382:K5607 RS08360
gene id: 1295382:K5607_RS08360
uniprot id: A0A8D5AKE0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1295382:K5607 RS16340
gene id: 1295382:K5607_RS16340
uniprot id: A0A8D5ALX6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1295382:K5607 RS10680
gene id: 1295382:K5607_RS10680
uniprot id: A0A8D4VQM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1295382:K5607 RS14840
gene id: 1295382:K5607_RS14840
uniprot id: A0A8D4VU26
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1295382:K5607 RS06585
gene id: 1295382:K5607_RS06585
uniprot id: A0A8D5AK27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1295382:K5607 RS13395
gene id: 1295382:K5607_RS13395
uniprot id: A0A8D5ALE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1295382:K5607 RS14575
gene id: 1295382:K5607_RS14575
uniprot id: A0A8D4VS41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1295382:K5607 RS13275
gene id: 1295382:K5607_RS13275
uniprot id: A0A8D4VTG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1295382:K5607 RS01940
gene id: 1295382:K5607_RS01940
uniprot id: A0A8D4VNG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1295382:K5607 RS05175
gene id: 1295382:K5607_RS05175
uniprot id: A0A8D4VLP0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1295382:K5607 RS10045
gene id: 1295382:K5607_RS10045
uniprot id: A0A8D5AHD2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1295382:K5607 RS13995
gene id: 1295382:K5607_RS13995
uniprot id: A0A8D5ANI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1295382:K5607 RS00900
gene id: 1295382:K5607_RS00900
uniprot id: A0A8D4VN23
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1295382:K5607 RS11510
gene id: 1295382:K5607_RS11510
uniprot id: A0A8D5AL04
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1295382:K5607 RS15675
gene id: 1295382:K5607_RS15675
uniprot id: A0A8D4VRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1295382:K5607 RS01450
gene id: 1295382:K5607_RS01450
uniprot id: A0A8D5AIF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1295382:K5607 RS09490
gene id: 1295382:K5607_RS09490
uniprot id: A0A8D4VQ07
names: Similarity
messages: Belongs to the YciI family.

1295382:K5607 RS03325
gene id: 1295382:K5607_RS03325
uniprot id: A0A8D4VLH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1295382:K5607 RS03320
gene id: 1295382:K5607_RS03320
uniprot id: A0A8D4VMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1295382:K5607 RS04935
gene id: 1295382:K5607_RS04935
uniprot id: A0A8D4VMM2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1295382:K5607 RS07300
gene id: 1295382:K5607_RS07300
uniprot id: A0A8D4VQL0
names: Similarity
messages: Belongs to the SlyX family.

1295382:K5607 RS11650
gene id: 1295382:K5607_RS11650
uniprot id: A0A8D5AHP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1295382:K5607 RS14210
gene id: 1295382:K5607_RS14210
uniprot id: A0A8D4VQY5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1295382:K5607 RS12525
gene id: 1295382:K5607_RS12525
uniprot id: A0A8D4VP72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1295382:K5607 RS12850
gene id: 1295382:K5607_RS12850
uniprot id: A0A8D5ANB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1295382:K5607 RS10530
gene id: 1295382:K5607_RS10530
uniprot id: A0A8D4VP27
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1295382:K5607 RS07630
gene id: 1295382:K5607_RS07630
uniprot id: A0A8D4VR57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1295382:K5607 RS02800
gene id: 1295382:K5607_RS02800
uniprot id: A0A8D4VLD8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.