1276258:SAPIS RS03615
gene id: 1276258:SAPIS_RS03615
uniprot id: V5RIQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1276258:SAPIS RS02605
gene id: 1276258:SAPIS_RS02605
uniprot id: V5RKK8
names: Similarity
messages: Belongs to the proline racemase family.

1276258:SAPIS RS04410
gene id: 1276258:SAPIS_RS04410
uniprot id: V5RLI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1276258:SAPIS RS04765
gene id: 1276258:SAPIS_RS04765
uniprot id: V5RJW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1276258:SAPIS RS04780
gene id: 1276258:SAPIS_RS04780
uniprot id: V5RKX5
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1276258:SAPIS RS04600
gene id: 1276258:SAPIS_RS04600
uniprot id: V5RLK8
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS04665
gene id: 1276258:SAPIS_RS04665
uniprot id: V5RJU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1276258:SAPIS RS01645
gene id: 1276258:SAPIS_RS01645
uniprot id: V5RHK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1276258:SAPIS RS01855
gene id: 1276258:SAPIS_RS01855
uniprot id: V5RIB1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1276258:SAPIS RS05025
gene id: 1276258:SAPIS_RS05025
uniprot id: V5RL20
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1276258:SAPIS RS01805
gene id: 1276258:SAPIS_RS01805
uniprot id: V5RIA2
names: Similarity
messages: Belongs to the peptidase M17 family.

1276258:SAPIS RS00185
gene id: 1276258:SAPIS_RS00185
uniprot id: V5RIE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1276258:SAPIS RS03795
gene id: 1276258:SAPIS_RS03795
uniprot id: V5RJ54
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276258:SAPIS RS00915
gene id: 1276258:SAPIS_RS00915
uniprot id: V5RJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1276258:SAPIS RS01555
gene id: 1276258:SAPIS_RS01555
uniprot id: V5RHX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS00240
gene id: 1276258:SAPIS_RS00240
uniprot id: V5RHF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1276258:SAPIS RS03350
gene id: 1276258:SAPIS_RS03350
uniprot id: V5RIY2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1276258:SAPIS RS04805
gene id: 1276258:SAPIS_RS04805
uniprot id: V5RKY1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1276258:SAPIS RS01345
gene id: 1276258:SAPIS_RS01345
uniprot id: V5RHG2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1276258:SAPIS RS01935
gene id: 1276258:SAPIS_RS01935
uniprot id: V5RI43
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS03620
gene id: 1276258:SAPIS_RS03620
uniprot id: V5RJB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1276258:SAPIS RS02080
gene id: 1276258:SAPIS_RS02080
uniprot id: V5RJF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1276258:SAPIS RS00500
gene id: 1276258:SAPIS_RS00500
uniprot id: V5RJI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1276258:SAPIS RS03865
gene id: 1276258:SAPIS_RS03865
uniprot id: V5RJ68
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1276258:SAPIS RS05030
gene id: 1276258:SAPIS_RS05030
uniprot id: V5RJE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1276258:SAPIS RS04955
gene id: 1276258:SAPIS_RS04955
uniprot id: V5RJD2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS04860
gene id: 1276258:SAPIS_RS04860
uniprot id: V5RJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1276258:SAPIS RS04210
gene id: 1276258:SAPIS_RS04210
uniprot id: V5RKM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1276258:SAPIS RS04595
gene id: 1276258:SAPIS_RS04595
uniprot id: V5RJK0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS02040
gene id: 1276258:SAPIS_RS02040
uniprot id: V5RIE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1276258:SAPIS RS04700
gene id: 1276258:SAPIS_RS04700
uniprot id: V5RLM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1276258:SAPIS RS03610
gene id: 1276258:SAPIS_RS03610
uniprot id: V5RKC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1276258:SAPIS RS00530
gene id: 1276258:SAPIS_RS00530
uniprot id: V5RIM3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1276258:SAPIS RS02875
gene id: 1276258:SAPIS_RS02875
uniprot id: V5RIL4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS04775
gene id: 1276258:SAPIS_RS04775
uniprot id: V5RLP4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1276258:SAPIS RS01215
gene id: 1276258:SAPIS_RS01215
uniprot id: V5RJ10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1276258:SAPIS RS00605
gene id: 1276258:SAPIS_RS00605
uniprot id: V5RHE3
names: Similarity
messages: Belongs to the thioredoxin family.

1276258:SAPIS RS00480
gene id: 1276258:SAPIS_RS00480
uniprot id: V5RIL1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1276258:SAPIS RS00485
gene id: 1276258:SAPIS_RS00485
uniprot id: V5RH06
names: Subcellular Location Annotation
messages: Cytoplasm

1276258:SAPIS RS01195
gene id: 1276258:SAPIS_RS01195
uniprot id: V5RHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1276258:SAPIS RS03605
gene id: 1276258:SAPIS_RS03605
uniprot id: V5RL70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276258:SAPIS RS04430
gene id: 1276258:SAPIS_RS04430
uniprot id: V5RJH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1276258:SAPIS RS00300
gene id: 1276258:SAPIS_RS00300
uniprot id: V5RJE0
names: Similarity
messages: Belongs to the HPrK/P family.

1276258:SAPIS RS00355
gene id: 1276258:SAPIS_RS00355
uniprot id: V5RII5
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS01675
gene id: 1276258:SAPIS_RS01675
uniprot id: V5RI78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1276258:SAPIS RS00835
gene id: 1276258:SAPIS_RS00835
uniprot id: V5RJQ5
names: Similarity
messages: Belongs to the CutC family.

1276258:SAPIS RS01560
gene id: 1276258:SAPIS_RS01560
uniprot id: V5RK21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS03010
gene id: 1276258:SAPIS_RS03010
uniprot id: V5RIB7
names: Similarity
messages: Belongs to the XseB family.

1276258:SAPIS RS01070
gene id: 1276258:SAPIS_RS01070
uniprot id: V5RHB4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS03820
gene id: 1276258:SAPIS_RS03820
uniprot id: V5RJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276258:SAPIS RS00280
gene id: 1276258:SAPIS_RS00280
uniprot id: V5RIH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1276258:SAPIS RS00060
gene id: 1276258:SAPIS_RS00060
uniprot id: V5RJ81
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1276258:SAPIS RS00340
gene id: 1276258:SAPIS_RS00340
uniprot id: V5RHH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1276258:SAPIS RS00090
gene id: 1276258:SAPIS_RS00090
uniprot id: V5RIC6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1276258:SAPIS RS05100
gene id: 1276258:SAPIS_RS05100
uniprot id: V5RLV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS04930
gene id: 1276258:SAPIS_RS04930
uniprot id: V5RL03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1276258:SAPIS RS04290
gene id: 1276258:SAPIS_RS04290
uniprot id: V5RKP1
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.

1276258:SAPIS RS03485
gene id: 1276258:SAPIS_RS03485
uniprot id: V5RKA6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1276258:SAPIS RS04260
gene id: 1276258:SAPIS_RS04260
uniprot id: V5RKN7
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS00410
gene id: 1276258:SAPIS_RS00410
uniprot id: V5RGZ0
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS01700
gene id: 1276258:SAPIS_RS01700
uniprot id: V5RI82
names: Similarity
messages: Belongs to the DprA/Smf family.

1276258:SAPIS RS04640
gene id: 1276258:SAPIS_RS04640
uniprot id: V5RJU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1276258:SAPIS RS01815
gene id: 1276258:SAPIS_RS01815
uniprot id: V5RK67
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1276258:SAPIS RS04110
gene id: 1276258:SAPIS_RS04110
uniprot id: V5RKL0
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276258:SAPIS RS03430
gene id: 1276258:SAPIS_RS03430
uniprot id: V5RL43
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1276258:SAPIS RS00695
gene id: 1276258:SAPIS_RS00695
uniprot id: V5RH32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

1276258:SAPIS RS04920
gene id: 1276258:SAPIS_RS04920
uniprot id: V5RJQ6
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1276258:SAPIS RS03910
gene id: 1276258:SAPIS_RS03910
uniprot id: V5RLB2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1276258:SAPIS RS04005
gene id: 1276258:SAPIS_RS04005
uniprot id: V5RLC8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1276258:SAPIS RS04740
gene id: 1276258:SAPIS_RS04740
uniprot id: V5RJW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1276258:SAPIS RS02420
gene id: 1276258:SAPIS_RS02420
uniprot id: V5RIK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS04745
gene id: 1276258:SAPIS_RS04745
uniprot id: V5RJM6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1276258:SAPIS RS01330
gene id: 1276258:SAPIS_RS01330
uniprot id: V5RHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1276258:SAPIS RS00345
gene id: 1276258:SAPIS_RS00345
uniprot id: V5RH95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1276258:SAPIS RS02660
gene id: 1276258:SAPIS_RS02660
uniprot id: V5RJR8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1276258:SAPIS RS04085
gene id: 1276258:SAPIS_RS04085
uniprot id: V5RKK6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1276258:SAPIS RS00800
gene id: 1276258:SAPIS_RS00800
uniprot id: V5RHS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1276258:SAPIS RS03635
gene id: 1276258:SAPIS_RS03635
uniprot id: V5RKD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1276258:SAPIS RS00175
gene id: 1276258:SAPIS_RS00175
uniprot id: V5RH64
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1276258:SAPIS RS01905
gene id: 1276258:SAPIS_RS01905
uniprot id: V5RIC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1276258:SAPIS RS00195
gene id: 1276258:SAPIS_RS00195
uniprot id: V5RHE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1276258:SAPIS RS01820
gene id: 1276258:SAPIS_RS01820
uniprot id: V5RJB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1276258:SAPIS RS00830
gene id: 1276258:SAPIS_RS00830
uniprot id: V5RHK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1276258:SAPIS RS04360
gene id: 1276258:SAPIS_RS04360
uniprot id: V5RLI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1276258:SAPIS RS03280
gene id: 1276258:SAPIS_RS03280
uniprot id: V5RL05
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS05000
gene id: 1276258:SAPIS_RS05000
uniprot id: V5RL16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1276258:SAPIS RS02300
gene id: 1276258:SAPIS_RS02300
uniprot id: V5RIA8
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1276258:SAPIS RS04370
gene id: 1276258:SAPIS_RS04370
uniprot id: V5RJ18
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1276258:SAPIS RS00450
gene id: 1276258:SAPIS_RS00450
uniprot id: V5RJH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1276258:SAPIS RS01840
gene id: 1276258:SAPIS_RS01840
uniprot id: V5RK71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS00445
gene id: 1276258:SAPIS_RS00445
uniprot id: V5RHB5
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276258:SAPIS RS00625
gene id: 1276258:SAPIS_RS00625
uniprot id: V5RHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276258:SAPIS RS04695
gene id: 1276258:SAPIS_RS04695
uniprot id: V5RJL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1276258:SAPIS RS04560
gene id: 1276258:SAPIS_RS04560
uniprot id: V5RJ48
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1276258:SAPIS RS02695
gene id: 1276258:SAPIS_RS02695
uniprot id: V5RIQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1276258:SAPIS RS04425
gene id: 1276258:SAPIS_RS04425
uniprot id: V5RJQ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276258:SAPIS RS00040
gene id: 1276258:SAPIS_RS00040
uniprot id: V5RIB5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1276258:SAPIS RS02215
gene id: 1276258:SAPIS_RS02215
uniprot id: V5RHV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1276258:SAPIS RS00085
gene id: 1276258:SAPIS_RS00085
uniprot id: V5RJ86
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1276258:SAPIS RS04760
gene id: 1276258:SAPIS_RS04760
uniprot id: V5RJ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1276258:SAPIS RS00230
gene id: 1276258:SAPIS_RS00230
uniprot id: V5RIG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1276258:SAPIS RS04650
gene id: 1276258:SAPIS_RS04650
uniprot id: V5RLL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1276258:SAPIS RS00975
gene id: 1276258:SAPIS_RS00975
uniprot id: V5RH97
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS05040
gene id: 1276258:SAPIS_RS05040
uniprot id: V5RJS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1276258:SAPIS RS01575
gene id: 1276258:SAPIS_RS01575
uniprot id: V5RHY1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1276258:SAPIS RS04385
gene id: 1276258:SAPIS_RS04385
uniprot id: V5RLI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276258:SAPIS RS00065
gene id: 1276258:SAPIS_RS00065
uniprot id: V5RIC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1276258:SAPIS RS05085
gene id: 1276258:SAPIS_RS05085
uniprot id: V5RJF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm

1276258:SAPIS RS01435
gene id: 1276258:SAPIS_RS01435
uniprot id: V5RK02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1276258:SAPIS RS00045
gene id: 1276258:SAPIS_RS00045
uniprot id: V5RGR5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1276258:SAPIS RS01785
gene id: 1276258:SAPIS_RS01785
uniprot id: V5RI18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1276258:SAPIS RS01605
gene id: 1276258:SAPIS_RS01605
uniprot id: V5RK31
names: Subcellular Location Annotation
messages: Cytoplasm

1276258:SAPIS RS00545
gene id: 1276258:SAPIS_RS00545
uniprot id: V5RHD7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1276258:SAPIS RS00025
gene id: 1276258:SAPIS_RS00025
uniprot id: V5RHA6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS02640
gene id: 1276258:SAPIS_RS02640
uniprot id: V5RI42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1276258:SAPIS RS01025
gene id: 1276258:SAPIS_RS01025
uniprot id: V5RHA5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1276258:SAPIS RS02290
gene id: 1276258:SAPIS_RS02290
uniprot id: V5RHX4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1276258:SAPIS RS00010
gene id: 1276258:SAPIS_RS00010
uniprot id: V5RIB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase.

1276258:SAPIS RS04295
gene id: 1276258:SAPIS_RS04295
uniprot id: V5RJ04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1276258:SAPIS RS00215
gene id: 1276258:SAPIS_RS00215
uniprot id: V5RGU8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1276258:SAPIS RS05110
gene id: 1276258:SAPIS_RS05110
uniprot id: V5RJG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS00180
gene id: 1276258:SAPIS_RS00180
uniprot id: V5RJA9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1276258:SAPIS RS00035
gene id: 1276258:SAPIS_RS00035
uniprot id: V5RJ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1276258:SAPIS RS03080
gene id: 1276258:SAPIS_RS03080
uniprot id: V5RK03
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1276258:SAPIS RS02650
gene id: 1276258:SAPIS_RS02650
uniprot id: V5RIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1276258:SAPIS RS05510
gene id: 1276258:SAPIS_RS05510
uniprot id: V5RL75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1276258:SAPIS RS00015
gene id: 1276258:SAPIS_RS00015
uniprot id: V5RGR0
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

1276258:SAPIS RS02755
gene id: 1276258:SAPIS_RS02755
uniprot id: V5RKN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1276258:SAPIS RS00235
gene id: 1276258:SAPIS_RS00235
uniprot id: V5RGV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1276258:SAPIS RS00110
gene id: 1276258:SAPIS_RS00110
uniprot id: V5RJ91
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS01205
gene id: 1276258:SAPIS_RS01205
uniprot id: V5RHR1
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS01765
gene id: 1276258:SAPIS_RS01765
uniprot id: V5RK58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1276258:SAPIS RS05130
gene id: 1276258:SAPIS_RS05130
uniprot id: V5RL40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1276258:SAPIS RS04555
gene id: 1276258:SAPIS_RS04555
uniprot id: V5RKT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1276258:SAPIS RS00285
gene id: 1276258:SAPIS_RS00285
uniprot id: V5RGW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1276258:SAPIS RS04655
gene id: 1276258:SAPIS_RS04655
uniprot id: V5RKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1276258:SAPIS RS04340
gene id: 1276258:SAPIS_RS04340
uniprot id: V5RKQ1
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS01020
gene id: 1276258:SAPIS_RS01020
uniprot id: V5RIX6
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS00245
gene id: 1276258:SAPIS_RS00245
uniprot id: V5RH78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1276258:SAPIS RS01220
gene id: 1276258:SAPIS_RS01220
uniprot id: V5RHE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1276258:SAPIS RS01570
gene id: 1276258:SAPIS_RS01570
uniprot id: V5RI62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1276258:SAPIS RS03465
gene id: 1276258:SAPIS_RS03465
uniprot id: V5RIN0
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS00260
gene id: 1276258:SAPIS_RS00260
uniprot id: V5RGV9
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1276258:SAPIS RS04500
gene id: 1276258:SAPIS_RS04500
uniprot id: V5RKS7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1276258:SAPIS RS02160
gene id: 1276258:SAPIS_RS02160
uniprot id: V5RJH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1276258:SAPIS RS05380
gene id: 1276258:SAPIS_RS05380
uniprot id: V5RIX5
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1276258:SAPIS RS02855
gene id: 1276258:SAPIS_RS02855
uniprot id: V5RKR0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1276258:SAPIS RS02985
gene id: 1276258:SAPIS_RS02985
uniprot id: V5RIB2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1276258:SAPIS RS03735
gene id: 1276258:SAPIS_RS03735
uniprot id: V5RIR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1276258:SAPIS RS02675
gene id: 1276258:SAPIS_RS02675
uniprot id: V5RIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276258:SAPIS RS02445
gene id: 1276258:SAPIS_RS02445
uniprot id: V5RIK9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1276258:SAPIS RS02935
gene id: 1276258:SAPIS_RS02935
uniprot id: V5RJX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

1276258:SAPIS RS05120
gene id: 1276258:SAPIS_RS05120
uniprot id: V5RJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Cell membrane
messages: Membrane

1276258:SAPIS RS02760
gene id: 1276258:SAPIS_RS02760
uniprot id: V5RJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1276258:SAPIS RS00740
gene id: 1276258:SAPIS_RS00740
uniprot id: V5RIQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1276258:SAPIS RS05195
gene id: 1276258:SAPIS_RS05195
uniprot id: V5RIU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1276258:SAPIS RS02095
gene id: 1276258:SAPIS_RS02095
uniprot id: V5RI69
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276258:SAPIS RS02365
gene id: 1276258:SAPIS_RS02365
uniprot id: V5RHY7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1276258:SAPIS RS00315
gene id: 1276258:SAPIS_RS00315
uniprot id: V5RHH0
names: Similarity
messages: Belongs to the Lgt family.

1276258:SAPIS RS02880
gene id: 1276258:SAPIS_RS02880
uniprot id: V5RKR5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS03875
gene id: 1276258:SAPIS_RS03875
uniprot id: V5RKH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1276258:SAPIS RS04660
gene id: 1276258:SAPIS_RS04660
uniprot id: V5RJ67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1276258:SAPIS RS03525
gene id: 1276258:SAPIS_RS03525
uniprot id: V5RJ17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1276258:SAPIS RS00700
gene id: 1276258:SAPIS_RS00700
uniprot id: V5RHN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS04535
gene id: 1276258:SAPIS_RS04535
uniprot id: V5RJ43
names: Similarity
messages: Belongs to the peptidase M13 family.

1276258:SAPIS RS01430
gene id: 1276258:SAPIS_RS01430
uniprot id: V5RHV2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS04690
gene id: 1276258:SAPIS_RS04690
uniprot id: V5RJV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1276258:SAPIS RS05015
gene id: 1276258:SAPIS_RS05015
uniprot id: V5RJS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276258:SAPIS RS02995
gene id: 1276258:SAPIS_RS02995
uniprot id: V5RIN8
names: Similarity
messages: Belongs to the NusB family.

1276258:SAPIS RS03825
gene id: 1276258:SAPIS_RS03825
uniprot id: V5RKG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1276258:SAPIS RS01825
gene id: 1276258:SAPIS_RS01825
uniprot id: V5RHP1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1276258:SAPIS RS03815
gene id: 1276258:SAPIS_RS03815
uniprot id: V5RJF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276258:SAPIS RS04770
gene id: 1276258:SAPIS_RS04770
uniprot id: V5RJM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1276258:SAPIS RS00335
gene id: 1276258:SAPIS_RS00335
uniprot id: V5RGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1276258:SAPIS RS01510
gene id: 1276258:SAPIS_RS01510
uniprot id: V5RK13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1276258:SAPIS RS02350
gene id: 1276258:SAPIS_RS02350
uniprot id: V5RIB8
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS04165
gene id: 1276258:SAPIS_RS04165
uniprot id: V5RIY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1276258:SAPIS RS01710
gene id: 1276258:SAPIS_RS01710
uniprot id: V5RK49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1276258:SAPIS RS03030
gene id: 1276258:SAPIS_RS03030
uniprot id: V5RJZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1276258:SAPIS RS03555
gene id: 1276258:SAPIS_RS03555
uniprot id: V5RL63
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1276258:SAPIS RS04735
gene id: 1276258:SAPIS_RS04735
uniprot id: V5RJ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1276258:SAPIS RS03245
gene id: 1276258:SAPIS_RS03245
uniprot id: V5RJ16
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS03835
gene id: 1276258:SAPIS_RS03835
uniprot id: V5RJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1276258:SAPIS RS01735
gene id: 1276258:SAPIS_RS01735
uniprot id: V5RI09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1276258:SAPIS RS05185
gene id: 1276258:SAPIS_RS05185
uniprot id: V5RJQ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1276258:SAPIS RS04710
gene id: 1276258:SAPIS_RS04710
uniprot id: V5RJ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1276258:SAPIS RS01725
gene id: 1276258:SAPIS_RS01725
uniprot id: V5RHM3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1276258:SAPIS RS04675
gene id: 1276258:SAPIS_RS04675
uniprot id: V5RLM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1276258:SAPIS RS01080
gene id: 1276258:SAPIS_RS01080
uniprot id: V5RHP3
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS00420
gene id: 1276258:SAPIS_RS00420
uniprot id: V5RHA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1276258:SAPIS RS04135
gene id: 1276258:SAPIS_RS04135
uniprot id: V5RKL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1276258:SAPIS RS04620
gene id: 1276258:SAPIS_RS04620
uniprot id: V5RJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1276258:SAPIS RS03880
gene id: 1276258:SAPIS_RS03880
uniprot id: V5RIT9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1276258:SAPIS RS01055
gene id: 1276258:SAPIS_RS01055
uniprot id: V5RHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276258:SAPIS RS04925
gene id: 1276258:SAPIS_RS04925
uniprot id: V5RLS2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1276258:SAPIS RS02775
gene id: 1276258:SAPIS_RS02775
uniprot id: V5RIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1276258:SAPIS RS03745
gene id: 1276258:SAPIS_RS03745
uniprot id: V5RJ47
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS04970
gene id: 1276258:SAPIS_RS04970
uniprot id: V5RLT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276258:SAPIS RS02965
gene id: 1276258:SAPIS_RS02965
uniprot id: V5RIA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1276258:SAPIS RS00955
gene id: 1276258:SAPIS_RS00955
uniprot id: V5RHV3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1276258:SAPIS RS04310
gene id: 1276258:SAPIS_RS04310
uniprot id: V5RLH3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1276258:SAPIS RS01585
gene id: 1276258:SAPIS_RS01585
uniprot id: V5RJ69
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1276258:SAPIS RS01520
gene id: 1276258:SAPIS_RS01520
uniprot id: V5RHI6
names: Similarity
messages: Belongs to the FBPase class 2 family.

1276258:SAPIS RS00790
gene id: 1276258:SAPIS_RS00790
uniprot id: V5RIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1276258:SAPIS RS04130
gene id: 1276258:SAPIS_RS04130
uniprot id: V5RLE7
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

1276258:SAPIS RS01110
gene id: 1276258:SAPIS_RS01110
uniprot id: V5RJV2
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS01295
gene id: 1276258:SAPIS_RS01295
uniprot id: V5RHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1276258:SAPIS RS05060
gene id: 1276258:SAPIS_RS05060
uniprot id: V5RJF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1276258:SAPIS RS00840
gene id: 1276258:SAPIS_RS00840
uniprot id: V5RIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1276258:SAPIS RS02200
gene id: 1276258:SAPIS_RS02200
uniprot id: V5RI89
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS02840
gene id: 1276258:SAPIS_RS02840
uniprot id: V5RI80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1276258:SAPIS RS04615
gene id: 1276258:SAPIS_RS04615
uniprot id: V5RJT7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1276258:SAPIS RS02185
gene id: 1276258:SAPIS_RS02185
uniprot id: V5RJH8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1276258:SAPIS RS00785
gene id: 1276258:SAPIS_RS00785
uniprot id: V5RJP9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS04645
gene id: 1276258:SAPIS_RS04645
uniprot id: V5RJK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1276258:SAPIS RS02175
gene id: 1276258:SAPIS_RS02175
uniprot id: V5RI83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1276258:SAPIS RS03930
gene id: 1276258:SAPIS_RS03930
uniprot id: V5RJ78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS04590
gene id: 1276258:SAPIS_RS04590
uniprot id: V5RJT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1276258:SAPIS RS03100
gene id: 1276258:SAPIS_RS03100
uniprot id: V5RKW2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1276258:SAPIS RS03645
gene id: 1276258:SAPIS_RS03645
uniprot id: V5RJC2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1276258:SAPIS RS01415
gene id: 1276258:SAPIS_RS01415
uniprot id: V5RJ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1276258:SAPIS RS01305
gene id: 1276258:SAPIS_RS01305
uniprot id: V5RHS8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1276258:SAPIS RS01760
gene id: 1276258:SAPIS_RS01760
uniprot id: V5RI14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1276258:SAPIS RS02790
gene id: 1276258:SAPIS_RS02790
uniprot id: V5RI72
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1276258:SAPIS RS04875
gene id: 1276258:SAPIS_RS04875
uniprot id: V5RLR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1276258:SAPIS RS04420
gene id: 1276258:SAPIS_RS04420
uniprot id: V5RJ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1276258:SAPIS RS00825
gene id: 1276258:SAPIS_RS00825
uniprot id: V5RHT0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1276258:SAPIS RS00630
gene id: 1276258:SAPIS_RS00630
uniprot id: V5RJK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276258:SAPIS RS00970
gene id: 1276258:SAPIS_RS00970
uniprot id: V5RIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1276258:SAPIS RS00125
gene id: 1276258:SAPIS_RS00125
uniprot id: V5RHC9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1276258:SAPIS RS04585
gene id: 1276258:SAPIS_RS04585
uniprot id: V5RJ52
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1276258:SAPIS RS04870
gene id: 1276258:SAPIS_RS04870
uniprot id: V5RJP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1276258:SAPIS RS01040
gene id: 1276258:SAPIS_RS01040
uniprot id: V5RJT9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1276258:SAPIS RS03760
gene id: 1276258:SAPIS_RS03760
uniprot id: V5RIS1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1276258:SAPIS RS03560
gene id: 1276258:SAPIS_RS03560
uniprot id: V5RKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1276258:SAPIS RS00220
gene id: 1276258:SAPIS_RS00220
uniprot id: V5RHF1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1276258:SAPIS RS00435
gene id: 1276258:SAPIS_RS00435
uniprot id: V5RGZ5
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276258:SAPIS RS03705
gene id: 1276258:SAPIS_RS03705
uniprot id: V5RKE2
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1276258:SAPIS RS03275
gene id: 1276258:SAPIS_RS03275
uniprot id: V5RIV2
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS04275
gene id: 1276258:SAPIS_RS04275
uniprot id: V5RJE3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1276258:SAPIS RS02520
gene id: 1276258:SAPIS_RS02520
uniprot id: V5RI17
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS03550
gene id: 1276258:SAPIS_RS03550
uniprot id: V5RJ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1276258:SAPIS RS00210
gene id: 1276258:SAPIS_RS00210
uniprot id: V5RIF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1276258:SAPIS RS00190
gene id: 1276258:SAPIS_RS00190
uniprot id: V5RGU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1276258:SAPIS RS03545
gene id: 1276258:SAPIS_RS03545
uniprot id: V5RJA3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1276258:SAPIS RS01580
gene id: 1276258:SAPIS_RS01580
uniprot id: V5RK26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1276258:SAPIS RS00150
gene id: 1276258:SAPIS_RS00150
uniprot id: V5RHD4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1276258:SAPIS RS04685
gene id: 1276258:SAPIS_RS04685
uniprot id: V5RJ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1276258:SAPIS RS00855
gene id: 1276258:SAPIS_RS00855
uniprot id: V5RHT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1276258:SAPIS RS00980
gene id: 1276258:SAPIS_RS00980
uniprot id: V5RHV8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1276258:SAPIS RS02945
gene id: 1276258:SAPIS_RS02945
uniprot id: V5RIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1276258:SAPIS RS01290
gene id: 1276258:SAPIS_RS01290
uniprot id: V5RJ23
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1276258:SAPIS RS04065
gene id: 1276258:SAPIS_RS04065
uniprot id: V5RIW5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1276258:SAPIS RS04320
gene id: 1276258:SAPIS_RS04320
uniprot id: V5RJ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1276258:SAPIS RS04025
gene id: 1276258:SAPIS_RS04025
uniprot id: V5RJ96
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1276258:SAPIS RS00120
gene id: 1276258:SAPIS_RS00120
uniprot id: V5RGS7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1276258:SAPIS RS01650
gene id: 1276258:SAPIS_RS01650
uniprot id: V5RI73
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276258:SAPIS RS04075
gene id: 1276258:SAPIS_RS04075
uniprot id: V5RJA6
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS04200
gene id: 1276258:SAPIS_RS04200
uniprot id: V5RJC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1276258:SAPIS RS00140
gene id: 1276258:SAPIS_RS00140
uniprot id: V5RID7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1276258:SAPIS RS00430
gene id: 1276258:SAPIS_RS00430
uniprot id: V5RIK0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1276258:SAPIS RS02020
gene id: 1276258:SAPIS_RS02020
uniprot id: V5RI56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1276258:SAPIS RS00415
gene id: 1276258:SAPIS_RS00415
uniprot id: V5RHI8
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1276258:SAPIS RS03860
gene id: 1276258:SAPIS_RS03860
uniprot id: V5RJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276258:SAPIS RS03585
gene id: 1276258:SAPIS_RS03585
uniprot id: V5RKC6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1276258:SAPIS RS01365
gene id: 1276258:SAPIS_RS01365
uniprot id: V5RJ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1276258:SAPIS RS04730
gene id: 1276258:SAPIS_RS04730
uniprot id: V5RKW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1276258:SAPIS RS04755
gene id: 1276258:SAPIS_RS04755
uniprot id: V5RKX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1276258:SAPIS RS02205
gene id: 1276258:SAPIS_RS02205
uniprot id: V5RKD4
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS03750
gene id: 1276258:SAPIS_RS03750
uniprot id: V5RL90
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1276258:SAPIS RS00310
gene id: 1276258:SAPIS_RS00310
uniprot id: V5RGW9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1276258:SAPIS RS03625
gene id: 1276258:SAPIS_RS03625
uniprot id: V5RJ32
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS01665
gene id: 1276258:SAPIS_RS01665
uniprot id: V5RJ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1276258:SAPIS RS03045
gene id: 1276258:SAPIS_RS03045
uniprot id: V5RIQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1276258:SAPIS RS02805
gene id: 1276258:SAPIS_RS02805
uniprot id: V5RKP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1276258:SAPIS RS05125
gene id: 1276258:SAPIS_RS05125
uniprot id: V5RLW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1276258:SAPIS RS04635
gene id: 1276258:SAPIS_RS04635
uniprot id: V5RJ62
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1276258:SAPIS RS03720
gene id: 1276258:SAPIS_RS03720
uniprot id: V5RJ44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS02635
gene id: 1276258:SAPIS_RS02635
uniprot id: V5RJR3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1276258:SAPIS RS00985
gene id: 1276258:SAPIS_RS00985
uniprot id: V5RHM5
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276258:SAPIS RS04625
gene id: 1276258:SAPIS_RS04625
uniprot id: V5RLL2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1276258:SAPIS RS03290
gene id: 1276258:SAPIS_RS03290
uniprot id: V5RIK1
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS00965
gene id: 1276258:SAPIS_RS00965
uniprot id: V5RJS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1276258:SAPIS RS03740
gene id: 1276258:SAPIS_RS03740
uniprot id: V5RJD6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1276258:SAPIS RS04850
gene id: 1276258:SAPIS_RS04850
uniprot id: V5RLQ8
names: Similarity
messages: Belongs to the peptidase M17 family.

1276258:SAPIS RS04570
gene id: 1276258:SAPIS_RS04570
uniprot id: V5RJJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS04335
gene id: 1276258:SAPIS_RS04335
uniprot id: V5RLH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1276258:SAPIS RS01740
gene id: 1276258:SAPIS_RS01740
uniprot id: V5RK53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1276258:SAPIS RS01545
gene id: 1276258:SAPIS_RS01545
uniprot id: V5RHJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1276258:SAPIS RS00205
gene id: 1276258:SAPIS_RS00205
uniprot id: V5RJB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1276258:SAPIS RS05010
gene id: 1276258:SAPIS_RS05010
uniprot id: V5RK16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1276258:SAPIS RS04815
gene id: 1276258:SAPIS_RS04815
uniprot id: V5RJX7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1276258:SAPIS RS04240
gene id: 1276258:SAPIS_RS04240
uniprot id: V5RIZ4
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS01210
gene id: 1276258:SAPIS_RS01210
uniprot id: V5RJW9
names: Similarity
messages: Belongs to the carbamate kinase family.

1276258:SAPIS RS00820
gene id: 1276258:SAPIS_RS00820
uniprot id: V5RH77
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1276258:SAPIS RS04315
gene id: 1276258:SAPIS_RS04315
uniprot id: V5RKP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1276258:SAPIS RS02070
gene id: 1276258:SAPIS_RS02070
uniprot id: V5RI64
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1276258:SAPIS RS05035
gene id: 1276258:SAPIS_RS05035
uniprot id: V5RK22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1276258:SAPIS RS03755
gene id: 1276258:SAPIS_RS03755
uniprot id: V5RKF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1276258:SAPIS RS04715
gene id: 1276258:SAPIS_RS04715
uniprot id: V5RJV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1276258:SAPIS RS03590
gene id: 1276258:SAPIS_RS03590
uniprot id: V5RIP8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1276258:SAPIS RS00440
gene id: 1276258:SAPIS_RS00440
uniprot id: V5RHJ3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1276258:SAPIS RS04810
gene id: 1276258:SAPIS_RS04810
uniprot id: V5RJ99
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1276258:SAPIS RS03015
gene id: 1276258:SAPIS_RS03015
uniprot id: V5RIW8
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1276258:SAPIS RS03005
gene id: 1276258:SAPIS_RS03005
uniprot id: V5RJY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1276258:SAPIS RS00320
gene id: 1276258:SAPIS_RS00320
uniprot id: V5RH92
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1276258:SAPIS RS04390
gene id: 1276258:SAPIS_RS04390
uniprot id: V5RKQ8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1276258:SAPIS RS02405
gene id: 1276258:SAPIS_RS02405
uniprot id: V5RKH3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1276258:SAPIS RS04630
gene id: 1276258:SAPIS_RS04630
uniprot id: V5RKV0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1276258:SAPIS RS04445
gene id: 1276258:SAPIS_RS04445
uniprot id: V5RJ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1276258:SAPIS RS02970
gene id: 1276258:SAPIS_RS02970
uniprot id: V5RIV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1276258:SAPIS RS04270
gene id: 1276258:SAPIS_RS04270
uniprot id: V5RJM8
names: Similarity
messages: Belongs to the asp23 family.

1276258:SAPIS RS00990
gene id: 1276258:SAPIS_RS00990
uniprot id: V5RJT3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1276258:SAPIS RS05005
gene id: 1276258:SAPIS_RS05005
uniprot id: V5RJE2
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS02865
gene id: 1276258:SAPIS_RS02865
uniprot id: V5RI85
names: Similarity
messages: Belongs to the RutC family.

1276258:SAPIS RS02860
gene id: 1276258:SAPIS_RS02860
uniprot id: V5RJW1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1276258:SAPIS RS04670
gene id: 1276258:SAPIS_RS04670
uniprot id: V5RJL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1276258:SAPIS RS04980
gene id: 1276258:SAPIS_RS04980
uniprot id: V5RJD7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1276258:SAPIS RS01680
gene id: 1276258:SAPIS_RS01680
uniprot id: V5RI00
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1276258:SAPIS RS02120
gene id: 1276258:SAPIS_RS02120
uniprot id: V5RIF7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1276258:SAPIS RS05090
gene id: 1276258:SAPIS_RS05090
uniprot id: V5RK33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1276258:SAPIS RS04950
gene id: 1276258:SAPIS_RS04950
uniprot id: V5RL08
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1276258:SAPIS RS02690
gene id: 1276258:SAPIS_RS02690
uniprot id: V5RI51
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS03130
gene id: 1276258:SAPIS_RS03130
uniprot id: V5RK17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276258:SAPIS RS00005
gene id: 1276258:SAPIS_RS00005
uniprot id: V5RJ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1276258:SAPIS RS02210
gene id: 1276258:SAPIS_RS02210
uniprot id: V5RJI3
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS00380
gene id: 1276258:SAPIS_RS00380
uniprot id: V5RIJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1276258:SAPIS RS04750
gene id: 1276258:SAPIS_RS04750
uniprot id: V5RLN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1276258:SAPIS RS04705
gene id: 1276258:SAPIS_RS04705
uniprot id: V5RKW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1276258:SAPIS RS02355
gene id: 1276258:SAPIS_RS02355
uniprot id: V5RKG3
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS02225
gene id: 1276258:SAPIS_RS02225
uniprot id: V5RI93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1276258:SAPIS RS03715
gene id: 1276258:SAPIS_RS03715
uniprot id: V5RJD1
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1276258:SAPIS RS01230
gene id: 1276258:SAPIS_RS01230
uniprot id: V5RHR5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1276258:SAPIS RS01250
gene id: 1276258:SAPIS_RS01250
uniprot id: V5RI06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS03395
gene id: 1276258:SAPIS_RS03395
uniprot id: V5RJ75
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS03840
gene id: 1276258:SAPIS_RS03840
uniprot id: V5RJ64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1276258:SAPIS RS00225
gene id: 1276258:SAPIS_RS00225
uniprot id: V5RJC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

1276258:SAPIS RS02230
gene id: 1276258:SAPIS_RS02230
uniprot id: V5RKD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1276258:SAPIS RS04565
gene id: 1276258:SAPIS_RS04565
uniprot id: V5RJS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1276258:SAPIS RS02255
gene id: 1276258:SAPIS_RS02255
uniprot id: V5RKE5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1276258:SAPIS RS01480
gene id: 1276258:SAPIS_RS01480
uniprot id: V5RHW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1276258:SAPIS RS00370
gene id: 1276258:SAPIS_RS00370
uniprot id: V5RHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276258:SAPIS RS02275
gene id: 1276258:SAPIS_RS02275
uniprot id: V5RIA3
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS04865
gene id: 1276258:SAPIS_RS04865
uniprot id: V5RJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1276258:SAPIS RS02250
gene id: 1276258:SAPIS_RS02250
uniprot id: V5RI98
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

1276258:SAPIS RS04975
gene id: 1276258:SAPIS_RS04975
uniprot id: V5RL11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS01030
gene id: 1276258:SAPIS_RS01030
uniprot id: V5RHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1276258:SAPIS RS00405
gene id: 1276258:SAPIS_RS00405
uniprot id: V5RIJ4
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS05070
gene id: 1276258:SAPIS_RS05070
uniprot id: V5RJT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1276258:SAPIS RS00475
gene id: 1276258:SAPIS_RS00475
uniprot id: V5RJH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1276258:SAPIS RS01705
gene id: 1276258:SAPIS_RS01705
uniprot id: V5RI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276258:SAPIS RS01670
gene id: 1276258:SAPIS_RS01670
uniprot id: V5RHL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1276258:SAPIS RS01875
gene id: 1276258:SAPIS_RS01875
uniprot id: V5RHP9
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS02850
gene id: 1276258:SAPIS_RS02850
uniprot id: V5RIK7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1276258:SAPIS RS01375
gene id: 1276258:SAPIS_RS01375
uniprot id: V5RI29
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS04845
gene id: 1276258:SAPIS_RS04845
uniprot id: V5RJP2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1276258:SAPIS RS02035
gene id: 1276258:SAPIS_RS02035
uniprot id: V5RHS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1276258:SAPIS RS00360
gene id: 1276258:SAPIS_RS00360
uniprot id: V5RGX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS00385
gene id: 1276258:SAPIS_RS00385
uniprot id: V5RGY5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS02415
gene id: 1276258:SAPIS_RS02415
uniprot id: V5RHZ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1276258:SAPIS RS00170
gene id: 1276258:SAPIS_RS00170
uniprot id: V5RHD9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1276258:SAPIS RS04095
gene id: 1276258:SAPIS_RS04095
uniprot id: V5RJJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1276258:SAPIS RS02830
gene id: 1276258:SAPIS_RS02830
uniprot id: V5RKQ3
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS02125
gene id: 1276258:SAPIS_RS02125
uniprot id: V5RI74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1276258:SAPIS RS01225
gene id: 1276258:SAPIS_RS01225
uniprot id: V5RI01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1276258:SAPIS RS01860
gene id: 1276258:SAPIS_RS01860
uniprot id: V5RI31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1276258:SAPIS RS04990
gene id: 1276258:SAPIS_RS04990
uniprot id: V5RJS1
names: Similarity
messages: Belongs to the ParB family.

1276258:SAPIS RS01090
gene id: 1276258:SAPIS_RS01090
uniprot id: V5RIY8
names: Subcellular Location Annotation
messages: Membrane

1276258:SAPIS RS03595
gene id: 1276258:SAPIS_RS03595
uniprot id: V5RJB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1276258:SAPIS RS00255
gene id: 1276258:SAPIS_RS00255
uniprot id: V5RIG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1276258:SAPIS RS02835
gene id: 1276258:SAPIS_RS02835
uniprot id: V5RJV6
names: Function
names: Similarity
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

1276258:SAPIS RS02050
gene id: 1276258:SAPIS_RS02050
uniprot id: V5RKA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1276258:SAPIS RS05155
gene id: 1276258:SAPIS_RS05155
uniprot id: V5RHJ6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276258:SAPIS RS00305
gene id: 1276258:SAPIS_RS00305
uniprot id: V5RIH5
names: Similarity
messages: Belongs to the Lgt family.

1276258:SAPIS RS04825
gene id: 1276258:SAPIS_RS04825
uniprot id: V5RLQ3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1276258:SAPIS RS00250
gene id: 1276258:SAPIS_RS00250
uniprot id: V5RJC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1276258:SAPIS RS01595
gene id: 1276258:SAPIS_RS01595
uniprot id: V5RI67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Cytoplasm

1276258:SAPIS RS00115
gene id: 1276258:SAPIS_RS00115
uniprot id: V5RID1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1276258:SAPIS RS04015
gene id: 1276258:SAPIS_RS04015
uniprot id: V5RIV7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1276258:SAPIS RS00275
gene id: 1276258:SAPIS_RS00275
uniprot id: V5RJD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1276258:SAPIS RS02525
gene id: 1276258:SAPIS_RS02525
uniprot id: V5RIM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1276258:SAPIS RS03025
gene id: 1276258:SAPIS_RS03025
uniprot id: V5RKU6
names: Similarity
messages: Belongs to the TlyA family.