1276229:SSYRP RS04925
gene id: 1276229:SSYRP_RS04925
uniprot id: R4UMT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1276229:SSYRP RS03225
gene id: 1276229:SSYRP_RS03225
uniprot id: R4UJC9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1276229:SSYRP RS02605
gene id: 1276229:SSYRP_RS02605
uniprot id: R4U3V5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1276229:SSYRP RS02220
gene id: 1276229:SSYRP_RS02220
uniprot id: R4U600
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1276229:SSYRP RS04795
gene id: 1276229:SSYRP_RS04795
uniprot id: R4UK55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1276229:SSYRP RS03130
gene id: 1276229:SSYRP_RS03130
uniprot id: R4UJB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1276229:SSYRP RS04855
gene id: 1276229:SSYRP_RS04855
uniprot id: R4U4Y5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1276229:SSYRP RS01420
gene id: 1276229:SSYRP_RS01420
uniprot id: R4UI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

1276229:SSYRP RS02680
gene id: 1276229:SSYRP_RS02680
uniprot id: R4UJ23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276229:SSYRP RS00960
gene id: 1276229:SSYRP_RS00960
uniprot id: R4UD09
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS02825
gene id: 1276229:SSYRP_RS02825
uniprot id: R4UE37
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1276229:SSYRP RS00470
gene id: 1276229:SSYRP_RS00470
uniprot id: R4U2U1
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03235
gene id: 1276229:SSYRP_RS03235
uniprot id: R4U463
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276229:SSYRP RS00710
gene id: 1276229:SSYRP_RS00710
uniprot id: R4UCX4
names: Similarity
messages: Belongs to the Lgt family.

1276229:SSYRP RS01825
gene id: 1276229:SSYRP_RS01825
uniprot id: R4UIG6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1276229:SSYRP RS05065
gene id: 1276229:SSYRP_RS05065
uniprot id: R4UFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1276229:SSYRP RS01185
gene id: 1276229:SSYRP_RS01185
uniprot id: R4U366
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1276229:SSYRP RS00405
gene id: 1276229:SSYRP_RS00405
uniprot id: R4UK87
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1276229:SSYRP RS01605
gene id: 1276229:SSYRP_RS01605
uniprot id: R4UKX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1276229:SSYRP RS01435
gene id: 1276229:SSYRP_RS01435
uniprot id: R4U5L0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1276229:SSYRP RS04295
gene id: 1276229:SSYRP_RS04295
uniprot id: R4UET4
names: Similarity
messages: Belongs to the thioredoxin family.

1276229:SSYRP RS03415
gene id: 1276229:SSYRP_RS03415
uniprot id: R4U6N0
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS04655
gene id: 1276229:SSYRP_RS04655
uniprot id: R4U775
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1276229:SSYRP RS02195
gene id: 1276229:SSYRP_RS02195
uniprot id: R4U5Z5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1276229:SSYRP RS00235
gene id: 1276229:SSYRP_RS00235
uniprot id: R4UCQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1276229:SSYRP RS00005
gene id: 1276229:SSYRP_RS00005
uniprot id: R4U2J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1276229:SSYRP RS03325
gene id: 1276229:SSYRP_RS03325
uniprot id: R4UJE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1276229:SSYRP RS00365
gene id: 1276229:SSYRP_RS00365
uniprot id: R4U549
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1276229:SSYRP RS02095
gene id: 1276229:SSYRP_RS02095
uniprot id: R4U5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276229:SSYRP RS00890
gene id: 1276229:SSYRP_RS00890
uniprot id: R4UI06
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1276229:SSYRP RS01930
gene id: 1276229:SSYRP_RS01930
uniprot id: R4UII3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS01730
gene id: 1276229:SSYRP_RS01730
uniprot id: R4UL03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1276229:SSYRP RS02245
gene id: 1276229:SSYRP_RS02245
uniprot id: R4U606
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1276229:SSYRP RS01315
gene id: 1276229:SSYRP_RS01315
uniprot id: R4U5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1276229:SSYRP RS00535
gene id: 1276229:SSYRP_RS00535
uniprot id: R4UCV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1276229:SSYRP RS01815
gene id: 1276229:SSYRP_RS01815
uniprot id: R4U5S7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1276229:SSYRP RS05145
gene id: 1276229:SSYRP_RS05145
uniprot id: R4UKE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1276229:SSYRP RS04000
gene id: 1276229:SSYRP_RS04000
uniprot id: R4UMC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS01460
gene id: 1276229:SSYRP_RS01460
uniprot id: R4U5L2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1276229:SSYRP RS02575
gene id: 1276229:SSYRP_RS02575
uniprot id: R4ULI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1276229:SSYRP RS03795
gene id: 1276229:SSYRP_RS03795
uniprot id: R4UJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1276229:SSYRP RS00180
gene id: 1276229:SSYRP_RS00180
uniprot id: R4U2Q4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1276229:SSYRP RS02025
gene id: 1276229:SSYRP_RS02025
uniprot id: R4U3K4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1276229:SSYRP RS03210
gene id: 1276229:SSYRP_RS03210
uniprot id: R4U460
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1276229:SSYRP RS01685
gene id: 1276229:SSYRP_RS01685
uniprot id: R4U3F1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS04140
gene id: 1276229:SSYRP_RS04140
uniprot id: R4U4J6
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS01135
gene id: 1276229:SSYRP_RS01135
uniprot id: R4U357
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1276229:SSYRP RS03115
gene id: 1276229:SSYRP_RS03115
uniprot id: R4U446
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1276229:SSYRP RS03095
gene id: 1276229:SSYRP_RS03095
uniprot id: R4U6H7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS04270
gene id: 1276229:SSYRP_RS04270
uniprot id: R4U717
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03450
gene id: 1276229:SSYRP_RS03450
uniprot id: R4UJH0
names: Subcellular Location Annotation
messages: cytosol

1276229:SSYRP RS01610
gene id: 1276229:SSYRP_RS01610
uniprot id: R4U3D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1276229:SSYRP RS01635
gene id: 1276229:SSYRP_RS01635
uniprot id: R4U3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1276229:SSYRP RS04875
gene id: 1276229:SSYRP_RS04875
uniprot id: R4UMR9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1276229:SSYRP RS01945
gene id: 1276229:SSYRP_RS01945
uniprot id: R4U5V4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1276229:SSYRP RS00450
gene id: 1276229:SSYRP_RS00450
uniprot id: R4UCT9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1276229:SSYRP RS04260
gene id: 1276229:SSYRP_RS04260
uniprot id: R4UMG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS04170
gene id: 1276229:SSYRP_RS04170
uniprot id: R4U700
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1276229:SSYRP RS04075
gene id: 1276229:SSYRP_RS04075
uniprot id: R4UMD4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1276229:SSYRP RS04945
gene id: 1276229:SSYRP_RS04945
uniprot id: R4UK95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1276229:SSYRP RS01715
gene id: 1276229:SSYRP_RS01715
uniprot id: R4U5Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1276229:SSYRP RS01780
gene id: 1276229:SSYRP_RS01780
uniprot id: R4UL17
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS00540
gene id: 1276229:SSYRP_RS00540
uniprot id: R4UHU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1276229:SSYRP RS03310
gene id: 1276229:SSYRP_RS03310
uniprot id: R4U475
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1276229:SSYRP RS04115
gene id: 1276229:SSYRP_RS04115
uniprot id: R4U6Z1
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS02500
gene id: 1276229:SSYRP_RS02500
uniprot id: R4ULG6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1276229:SSYRP RS04935
gene id: 1276229:SSYRP_RS04935
uniprot id: R4U7C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS01305
gene id: 1276229:SSYRP_RS01305
uniprot id: R4UKR1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1276229:SSYRP RS00520
gene id: 1276229:SSYRP_RS00520
uniprot id: R4UKA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1276229:SSYRP RS04710
gene id: 1276229:SSYRP_RS04710
uniprot id: R4U783
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1276229:SSYRP RS02310
gene id: 1276229:SSYRP_RS02310
uniprot id: R4U620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1276229:SSYRP RS04630
gene id: 1276229:SSYRP_RS04630
uniprot id: R4U771
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1276229:SSYRP RS05140
gene id: 1276229:SSYRP_RS05140
uniprot id: R4UFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Cell membrane
messages: Membrane

1276229:SSYRP RS01075
gene id: 1276229:SSYRP_RS01075
uniprot id: R4UI36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1276229:SSYRP RS02145
gene id: 1276229:SSYRP_RS02145
uniprot id: R4U5Y5
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS02795
gene id: 1276229:SSYRP_RS02795
uniprot id: R4U6E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1276229:SSYRP RS02485
gene id: 1276229:SSYRP_RS02485
uniprot id: R4U652
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1276229:SSYRP RS01555
gene id: 1276229:SSYRP_RS01555
uniprot id: R4UKW6
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03290
gene id: 1276229:SSYRP_RS03290
uniprot id: R4U6K8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS02945
gene id: 1276229:SSYRP_RS02945
uniprot id: R4U6G0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1276229:SSYRP RS00165
gene id: 1276229:SSYRP_RS00165
uniprot id: R4UCN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1276229:SSYRP RS04665
gene id: 1276229:SSYRP_RS04665
uniprot id: R4UK23
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS01385
gene id: 1276229:SSYRP_RS01385
uniprot id: R4U5K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1276229:SSYRP RS03350
gene id: 1276229:SSYRP_RS03350
uniprot id: R4UJF2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1276229:SSYRP RS02965
gene id: 1276229:SSYRP_RS02965
uniprot id: R4U424
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS00720
gene id: 1276229:SSYRP_RS00720
uniprot id: R4UKE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1276229:SSYRP RS02765
gene id: 1276229:SSYRP_RS02765
uniprot id: R4U400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1276229:SSYRP RS03540
gene id: 1276229:SSYRP_RS03540
uniprot id: R4UEE3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1276229:SSYRP RS03175
gene id: 1276229:SSYRP_RS03175
uniprot id: R4UE88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276229:SSYRP RS01550
gene id: 1276229:SSYRP_RS01550
uniprot id: R4UIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1276229:SSYRP RS01265
gene id: 1276229:SSYRP_RS01265
uniprot id: R4U5I1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1276229:SSYRP RS05150
gene id: 1276229:SSYRP_RS05150
uniprot id: R4UMZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1276229:SSYRP RS00810
gene id: 1276229:SSYRP_RS00810
uniprot id: R4UCY8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1276229:SSYRP RS03165
gene id: 1276229:SSYRP_RS03165
uniprot id: R4U453
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1276229:SSYRP RS00080
gene id: 1276229:SSYRP_RS00080
uniprot id: R4U2L7
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS01670
gene id: 1276229:SSYRP_RS01670
uniprot id: R4UDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1276229:SSYRP RS03040
gene id: 1276229:SSYRP_RS03040
uniprot id: R4U434
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1276229:SSYRP RS03715
gene id: 1276229:SSYRP_RS03715
uniprot id: R4UEH7
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276229:SSYRP RS04065
gene id: 1276229:SSYRP_RS04065
uniprot id: R4UEP0
names: Similarity
messages: Belongs to the asp23 family.

1276229:SSYRP RS02155
gene id: 1276229:SSYRP_RS02155
uniprot id: R4UIL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1276229:SSYRP RS00950
gene id: 1276229:SSYRP_RS00950
uniprot id: R4U327
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1276229:SSYRP RS01025
gene id: 1276229:SSYRP_RS01025
uniprot id: R4U340
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS03695
gene id: 1276229:SSYRP_RS03695
uniprot id: R4UJL6
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS05050
gene id: 1276229:SSYRP_RS05050
uniprot id: R4UMW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1276229:SSYRP RS02955
gene id: 1276229:SSYRP_RS02955
uniprot id: R4UJ80
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1276229:SSYRP RS01410
gene id: 1276229:SSYRP_RS01410
uniprot id: R4U5K6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1276229:SSYRP RS01105
gene id: 1276229:SSYRP_RS01105
uniprot id: R4UKL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1276229:SSYRP RS01440
gene id: 1276229:SSYRP_RS01440
uniprot id: R4UD93
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1276229:SSYRP RS05055
gene id: 1276229:SSYRP_RS05055
uniprot id: R4U519
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1276229:SSYRP RS01115
gene id: 1276229:SSYRP_RS01115
uniprot id: R4U5F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1276229:SSYRP RS02845
gene id: 1276229:SSYRP_RS02845
uniprot id: R4U6E8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276229:SSYRP RS05100
gene id: 1276229:SSYRP_RS05100
uniprot id: R4UMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1276229:SSYRP RS03255
gene id: 1276229:SSYRP_RS03255
uniprot id: R4ULY8
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03830
gene id: 1276229:SSYRP_RS03830
uniprot id: R4U4F2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1276229:SSYRP RS02940
gene id: 1276229:SSYRP_RS02940
uniprot id: R4U420
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1276229:SSYRP RS02870
gene id: 1276229:SSYRP_RS02870
uniprot id: R4U6F1
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1276229:SSYRP RS02135
gene id: 1276229:SSYRP_RS02135
uniprot id: R4UL74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1276229:SSYRP RS02185
gene id: 1276229:SSYRP_RS02185
uniprot id: R4UL83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1276229:SSYRP RS01865
gene id: 1276229:SSYRP_RS01865
uniprot id: R4U5T7
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1276229:SSYRP RS05070
gene id: 1276229:SSYRP_RS05070
uniprot id: R4UKC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1276229:SSYRP RS02930
gene id: 1276229:SSYRP_RS02930
uniprot id: R4UJ74
names: Similarity
messages: Belongs to the RutC family.

1276229:SSYRP RS01200
gene id: 1276229:SSYRP_RS01200
uniprot id: R4UI59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1276229:SSYRP RS04695
gene id: 1276229:SSYRP_RS04695
uniprot id: R4UK29
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1276229:SSYRP RS05160
gene id: 1276229:SSYRP_RS05160
uniprot id: R4U3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1276229:SSYRP RS04850
gene id: 1276229:SSYRP_RS04850
uniprot id: R4UMQ9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1276229:SSYRP RS00725
gene id: 1276229:SSYRP_RS00725
uniprot id: R4U2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1276229:SSYRP RS03080
gene id: 1276229:SSYRP_RS03080
uniprot id: R4UJA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1276229:SSYRP RS00545
gene id: 1276229:SSYRP_RS00545
uniprot id: R4UKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1276229:SSYRP RS02800
gene id: 1276229:SSYRP_RS02800
uniprot id: R4UE34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1276229:SSYRP RS01160
gene id: 1276229:SSYRP_RS01160
uniprot id: R4U361
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1276229:SSYRP RS00065
gene id: 1276229:SSYRP_RS00065
uniprot id: R4UCJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1276229:SSYRP RS01915
gene id: 1276229:SSYRP_RS01915
uniprot id: R4U3J2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1276229:SSYRP RS04090
gene id: 1276229:SSYRP_RS04090
uniprot id: R4U6Y7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1276229:SSYRP RS01545
gene id: 1276229:SSYRP_RS01545
uniprot id: R4UDB6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1276229:SSYRP RS01100
gene id: 1276229:SSYRP_RS01100
uniprot id: R4UI41
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1276229:SSYRP RS04600
gene id: 1276229:SSYRP_RS04600
uniprot id: R4UK11
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1276229:SSYRP RS03780
gene id: 1276229:SSYRP_RS03780
uniprot id: R4U4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1276229:SSYRP RS05120
gene id: 1276229:SSYRP_RS05120
uniprot id: R4UKE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276229:SSYRP RS03285
gene id: 1276229:SSYRP_RS03285
uniprot id: R4U470
names: Similarity
messages: Belongs to the pyruvate kinase family.

1276229:SSYRP RS01735
gene id: 1276229:SSYRP_RS01735
uniprot id: R4U3G0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1276229:SSYRP RS01920
gene id: 1276229:SSYRP_RS01920
uniprot id: R4U5U7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1276229:SSYRP RS03755
gene id: 1276229:SSYRP_RS03755
uniprot id: R4U4D9
names: Subcellular Location Annotation
messages: Cytoplasm

1276229:SSYRP RS02755
gene id: 1276229:SSYRP_RS02755
uniprot id: R4UJ44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1276229:SSYRP RS01895
gene id: 1276229:SSYRP_RS01895
uniprot id: R4UDI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1276229:SSYRP RS02495
gene id: 1276229:SSYRP_RS02495
uniprot id: R4UIV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

1276229:SSYRP RS02490
gene id: 1276229:SSYRP_RS02490
uniprot id: R4UDW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS03560
gene id: 1276229:SSYRP_RS03560
uniprot id: R4U6Q5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1276229:SSYRP RS03320
gene id: 1276229:SSYRP_RS03320
uniprot id: R4UEB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1276229:SSYRP RS01005
gene id: 1276229:SSYRP_RS01005
uniprot id: R4U5D7
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1276229:SSYRP RS03675
gene id: 1276229:SSYRP_RS03675
uniprot id: R4UM65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1276229:SSYRP RS01155
gene id: 1276229:SSYRP_RS01155
uniprot id: R4UKM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1276229:SSYRP RS00935
gene id: 1276229:SSYRP_RS00935
uniprot id: R4UD05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1276229:SSYRP RS02510
gene id: 1276229:SSYRP_RS02510
uniprot id: R4U657
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS04420
gene id: 1276229:SSYRP_RS04420
uniprot id: R4U736
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1276229:SSYRP RS03725
gene id: 1276229:SSYRP_RS03725
uniprot id: R4UM76
names: Subcellular Location Annotation
messages: cytosol

1276229:SSYRP RS00585
gene id: 1276229:SSYRP_RS00585
uniprot id: R4UCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1276229:SSYRP RS01540
gene id: 1276229:SSYRP_RS01540
uniprot id: R4U5M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1276229:SSYRP RS03995
gene id: 1276229:SSYRP_RS03995
uniprot id: R4UJR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1276229:SSYRP RS04245
gene id: 1276229:SSYRP_RS04245
uniprot id: R4U713
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276229:SSYRP RS01475
gene id: 1276229:SSYRP_RS01475
uniprot id: R4UKV0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1276229:SSYRP RS01290
gene id: 1276229:SSYRP_RS01290
uniprot id: R4U5I6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1276229:SSYRP RS00910
gene id: 1276229:SSYRP_RS00910
uniprot id: R4UD01
names: Similarity
messages: Belongs to the RpoE family.

1276229:SSYRP RS00600
gene id: 1276229:SSYRP_RS00600
uniprot id: R4U2W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1276229:SSYRP RS05000
gene id: 1276229:SSYRP_RS05000
uniprot id: R4UMU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1276229:SSYRP RS04415
gene id: 1276229:SSYRP_RS04415
uniprot id: R4U4Q1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1276229:SSYRP RS01885
gene id: 1276229:SSYRP_RS01885
uniprot id: R4U3I7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1276229:SSYRP RS00360
gene id: 1276229:SSYRP_RS00360
uniprot id: R4U2S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1276229:SSYRP RS00785
gene id: 1276229:SSYRP_RS00785
uniprot id: R4UCY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1276229:SSYRP RS00410
gene id: 1276229:SSYRP_RS00410
uniprot id: R4U2T4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1276229:SSYRP RS01725
gene id: 1276229:SSYRP_RS01725
uniprot id: R4UIE8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1276229:SSYRP RS01195
gene id: 1276229:SSYRP_RS01195
uniprot id: R4UD45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1276229:SSYRP RS00045
gene id: 1276229:SSYRP_RS00045
uniprot id: R4UHH2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1276229:SSYRP RS00955
gene id: 1276229:SSYRP_RS00955
uniprot id: R4U5C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1276229:SSYRP RS00010
gene id: 1276229:SSYRP_RS00010
uniprot id: R4U4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase.

1276229:SSYRP RS00915
gene id: 1276229:SSYRP_RS00915
uniprot id: R4UI10
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS02675
gene id: 1276229:SSYRP_RS02675
uniprot id: R4UE05
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1276229:SSYRP RS00355
gene id: 1276229:SSYRP_RS00355
uniprot id: R4UK78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1276229:SSYRP RS04315
gene id: 1276229:SSYRP_RS04315
uniprot id: R4U723
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1276229:SSYRP RS03405
gene id: 1276229:SSYRP_RS03405
uniprot id: R4UM13
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1276229:SSYRP RS00130
gene id: 1276229:SSYRP_RS00130
uniprot id: R4U2N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1276229:SSYRP RS01090
gene id: 1276229:SSYRP_RS01090
uniprot id: R4U5F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1276229:SSYRP RS02635
gene id: 1276229:SSYRP_RS02635
uniprot id: R4U681
names: Similarity
messages: Belongs to the TlyA family.

1276229:SSYRP RS02960
gene id: 1276229:SSYRP_RS02960
uniprot id: R4ULU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1276229:SSYRP RS00515
gene id: 1276229:SSYRP_RS00515
uniprot id: R4UHU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

1276229:SSYRP RS02760
gene id: 1276229:SSYRP_RS02760
uniprot id: R4ULR2
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03965
gene id: 1276229:SSYRP_RS03965
uniprot id: R4UEN0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276229:SSYRP RS00595
gene id: 1276229:SSYRP_RS00595
uniprot id: R4UKC1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1276229:SSYRP RS02975
gene id: 1276229:SSYRP_RS02975
uniprot id: R4UE57
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1276229:SSYRP RS03145
gene id: 1276229:SSYRP_RS03145
uniprot id: R4U6I3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1276229:SSYRP RS01130
gene id: 1276229:SSYRP_RS01130
uniprot id: R4UKM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1276229:SSYRP RS03610
gene id: 1276229:SSYRP_RS03610
uniprot id: R4U6R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1276229:SSYRP RS00495
gene id: 1276229:SSYRP_RS00495
uniprot id: R4U2U6
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1276229:SSYRP RS03370
gene id: 1276229:SSYRP_RS03370
uniprot id: R4UEB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1276229:SSYRP RS02920
gene id: 1276229:SSYRP_RS02920
uniprot id: R4U6F7
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS04435
gene id: 1276229:SSYRP_RS04435
uniprot id: R4UMJ5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1276229:SSYRP RS01595
gene id: 1276229:SSYRP_RS01595
uniprot id: R4UDC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1276229:SSYRP RS02770
gene id: 1276229:SSYRP_RS02770
uniprot id: R4U6D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1276229:SSYRP RS03825
gene id: 1276229:SSYRP_RS03825
uniprot id: R4UM96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1276229:SSYRP RS01705
gene id: 1276229:SSYRP_RS01705
uniprot id: R4UKZ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS00015
gene id: 1276229:SSYRP_RS00015
uniprot id: R4UCH8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1276229:SSYRP RS00925
gene id: 1276229:SSYRP_RS00925
uniprot id: R4U323
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1276229:SSYRP RS00020
gene id: 1276229:SSYRP_RS00020
uniprot id: R4UHG6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1276229:SSYRP RS03345
gene id: 1276229:SSYRP_RS03345
uniprot id: R4UEB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1276229:SSYRP RS03940
gene id: 1276229:SSYRP_RS03940
uniprot id: R4UEM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1276229:SSYRP RS00095
gene id: 1276229:SSYRP_RS00095
uniprot id: R4UHI5
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS00575
gene id: 1276229:SSYRP_RS00575
uniprot id: R4U2V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1276229:SSYRP RS00370
gene id: 1276229:SSYRP_RS00370
uniprot id: R4UCS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1276229:SSYRP RS00875
gene id: 1276229:SSYRP_RS00875
uniprot id: R4U313
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1276229:SSYRP RS01615
gene id: 1276229:SSYRP_RS01615
uniprot id: R4U5N6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1276229:SSYRP RS02805
gene id: 1276229:SSYRP_RS02805
uniprot id: R4UJ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1276229:SSYRP RS01820
gene id: 1276229:SSYRP_RS01820
uniprot id: R4UDG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1276229:SSYRP RS04680
gene id: 1276229:SSYRP_RS04680
uniprot id: R4U4U9
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03420
gene id: 1276229:SSYRP_RS03420
uniprot id: R4UEC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1276229:SSYRP RS01295
gene id: 1276229:SSYRP_RS01295
uniprot id: R4UD62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1276229:SSYRP RS04740
gene id: 1276229:SSYRP_RS04740
uniprot id: R4UF23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1276229:SSYRP RS03230
gene id: 1276229:SSYRP_RS03230
uniprot id: R4ULY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1276229:SSYRP RS03170
gene id: 1276229:SSYRP_RS03170
uniprot id: R4U6I8
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03605
gene id: 1276229:SSYRP_RS03605
uniprot id: R4U4B6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1276229:SSYRP RS04430
gene id: 1276229:SSYRP_RS04430
uniprot id: R4UJX7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1276229:SSYRP RS02030
gene id: 1276229:SSYRP_RS02030
uniprot id: R4U5W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS05045
gene id: 1276229:SSYRP_RS05045
uniprot id: R4UKC3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1276229:SSYRP RS04400
gene id: 1276229:SSYRP_RS04400
uniprot id: R4UEU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1276229:SSYRP RS05135
gene id: 1276229:SSYRP_RS05135
uniprot id: R4U7H3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS05035
gene id: 1276229:SSYRP_RS05035
uniprot id: R4U7F3
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS01720
gene id: 1276229:SSYRP_RS01720
uniprot id: R4UDE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1276229:SSYRP RS02740
gene id: 1276229:SSYRP_RS02740
uniprot id: R4U3Z6
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03305
gene id: 1276229:SSYRP_RS03305
uniprot id: R4ULZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1276229:SSYRP RS01230
gene id: 1276229:SSYRP_RS01230
uniprot id: R4UKP5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1276229:SSYRP RS02840
gene id: 1276229:SSYRP_RS02840
uniprot id: R4U408
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1276229:SSYRP RS03770
gene id: 1276229:SSYRP_RS03770
uniprot id: R4UJM7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1276229:SSYRP RS03100
gene id: 1276229:SSYRP_RS03100
uniprot id: R4UE77
names: Function
names: Similarity
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

1276229:SSYRP RS03330
gene id: 1276229:SSYRP_RS03330
uniprot id: R4UM00
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1276229:SSYRP RS05075
gene id: 1276229:SSYRP_RS05075
uniprot id: R4UMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1276229:SSYRP RS02080
gene id: 1276229:SSYRP_RS02080
uniprot id: R4UIK0
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1276229:SSYRP RS03690
gene id: 1276229:SSYRP_RS03690
uniprot id: R4UEH3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1276229:SSYRP RS04175
gene id: 1276229:SSYRP_RS04175
uniprot id: R4UER2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1276229:SSYRP RS02075
gene id: 1276229:SSYRP_RS02075
uniprot id: R4UDL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS00650
gene id: 1276229:SSYRP_RS00650
uniprot id: R4U2X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276229:SSYRP RS01590
gene id: 1276229:SSYRP_RS01590
uniprot id: R4U5N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1276229:SSYRP RS04570
gene id: 1276229:SSYRP_RS04570
uniprot id: R4UEY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1276229:SSYRP RS04370
gene id: 1276229:SSYRP_RS04370
uniprot id: R4U727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1276229:SSYRP RS03150
gene id: 1276229:SSYRP_RS03150
uniprot id: R4UE83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1276229:SSYRP RS01710
gene id: 1276229:SSYRP_RS01710
uniprot id: R4U3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1276229:SSYRP RS01190
gene id: 1276229:SSYRP_RS01190
uniprot id: R4U5G8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1276229:SSYRP RS01970
gene id: 1276229:SSYRP_RS01970
uniprot id: R4U5V9
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03155
gene id: 1276229:SSYRP_RS03155
uniprot id: R4UJB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1276229:SSYRP RS00685
gene id: 1276229:SSYRP_RS00685
uniprot id: R4UCX1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1276229:SSYRP RS01210
gene id: 1276229:SSYRP_RS01210
uniprot id: R4U370
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1276229:SSYRP RS02175
gene id: 1276229:SSYRP_RS02175
uniprot id: R4UDN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1276229:SSYRP RS00135
gene id: 1276229:SSYRP_RS00135
uniprot id: R4U4Y9
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS01095
gene id: 1276229:SSYRP_RS01095
uniprot id: R4UD28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1276229:SSYRP RS01145
gene id: 1276229:SSYRP_RS01145
uniprot id: R4UD35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1276229:SSYRP RS03550
gene id: 1276229:SSYRP_RS03550
uniprot id: R4UM41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1276229:SSYRP RS03680
gene id: 1276229:SSYRP_RS03680
uniprot id: R4U4C6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1276229:SSYRP RS02790
gene id: 1276229:SSYRP_RS02790
uniprot id: R4U401
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1276229:SSYRP RS03820
gene id: 1276229:SSYRP_RS03820
uniprot id: R4UJN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1276229:SSYRP RS01470
gene id: 1276229:SSYRP_RS01470
uniprot id: R4UIA7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1276229:SSYRP RS03985
gene id: 1276229:SSYRP_RS03985
uniprot id: R4U6X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1276229:SSYRP RS04110
gene id: 1276229:SSYRP_RS04110
uniprot id: R4U4J0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1276229:SSYRP RS03955
gene id: 1276229:SSYRP_RS03955
uniprot id: R4U4H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1276229:SSYRP RS02885
gene id: 1276229:SSYRP_RS02885
uniprot id: R4ULT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1276229:SSYRP RS01085
gene id: 1276229:SSYRP_RS01085
uniprot id: R4U348
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1276229:SSYRP RS00835
gene id: 1276229:SSYRP_RS00835
uniprot id: R4UCZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1276229:SSYRP RS01755
gene id: 1276229:SSYRP_RS01755
uniprot id: R4UL10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1276229:SSYRP RS00580
gene id: 1276229:SSYRP_RS00580
uniprot id: R4U574
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1276229:SSYRP RS05165
gene id: 1276229:SSYRP_RS05165
uniprot id: R4U3N7
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS00645
gene id: 1276229:SSYRP_RS00645
uniprot id: R4UKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276229:SSYRP RS00995
gene id: 1276229:SSYRP_RS00995
uniprot id: R4UKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1276229:SSYRP RS01575
gene id: 1276229:SSYRP_RS01575
uniprot id: R4UIC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1276229:SSYRP RS01170
gene id: 1276229:SSYRP_RS01170
uniprot id: R4UD40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1276229:SSYRP RS01110
gene id: 1276229:SSYRP_RS01110
uniprot id: R4U353
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1276229:SSYRP RS01050
gene id: 1276229:SSYRP_RS01050
uniprot id: R4UI31
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1276229:SSYRP RS03385
gene id: 1276229:SSYRP_RS03385
uniprot id: R4U484
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1276229:SSYRP RS05105
gene id: 1276229:SSYRP_RS05105
uniprot id: R4U529
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1276229:SSYRP RS04785
gene id: 1276229:SSYRP_RS04785
uniprot id: R4U796
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1276229:SSYRP RS04800
gene id: 1276229:SSYRP_RS04800
uniprot id: R4UMP8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1276229:SSYRP RS01585
gene id: 1276229:SSYRP_RS01585
uniprot id: R4U3D3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1276229:SSYRP RS00120
gene id: 1276229:SSYRP_RS00120
uniprot id: R4UHJ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1276229:SSYRP RS04955
gene id: 1276229:SSYRP_RS04955
uniprot id: R4U502
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS00965
gene id: 1276229:SSYRP_RS00965
uniprot id: R4UI19
names: Similarity
messages: Belongs to the carbamate kinase family.

1276229:SSYRP RS04455
gene id: 1276229:SSYRP_RS04455
uniprot id: R4UJY1
names: Similarity
messages: Belongs to the FBPase class 2 family.

1276229:SSYRP RS00220
gene id: 1276229:SSYRP_RS00220
uniprot id: R4UHP8
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS00480
gene id: 1276229:SSYRP_RS00480
uniprot id: R4UCU3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1276229:SSYRP RS00715
gene id: 1276229:SSYRP_RS00715
uniprot id: R4UHX8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1276229:SSYRP RS04995
gene id: 1276229:SSYRP_RS04995
uniprot id: R4UKA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1276229:SSYRP RS04095
gene id: 1276229:SSYRP_RS04095
uniprot id: R4UEP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1276229:SSYRP RS01055
gene id: 1276229:SSYRP_RS01055
uniprot id: R4UKK7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1276229:SSYRP RS00100
gene id: 1276229:SSYRP_RS00100
uniprot id: R4UJX9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1276229:SSYRP RS01860
gene id: 1276229:SSYRP_RS01860
uniprot id: R4U3I3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1276229:SSYRP RS04070
gene id: 1276229:SSYRP_RS04070
uniprot id: R4UJR8
names: Function
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.

1276229:SSYRP RS04475
gene id: 1276229:SSYRP_RS04475
uniprot id: R4UEW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1276229:SSYRP RS00040
gene id: 1276229:SSYRP_RS00040
uniprot id: R4UCI4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1276229:SSYRP RS02475
gene id: 1276229:SSYRP_RS02475
uniprot id: R4ULF9
names: Similarity
messages: Belongs to the UPF0236 family.

1276229:SSYRP RS02980
gene id: 1276229:SSYRP_RS02980
uniprot id: R4UJ85
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1276229:SSYRP RS03220
gene id: 1276229:SSYRP_RS03220
uniprot id: R4UE96
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1276229:SSYRP RS04500
gene id: 1276229:SSYRP_RS04500
uniprot id: R4UEW6
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1276229:SSYRP RS01065
gene id: 1276229:SSYRP_RS01065
uniprot id: R4U5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1276229:SSYRP RS00980
gene id: 1276229:SSYRP_RS00980
uniprot id: R4U5D2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1276229:SSYRP RS04135
gene id: 1276229:SSYRP_RS04135
uniprot id: R4UME3
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS00530
gene id: 1276229:SSYRP_RS00530
uniprot id: R4U569
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1276229:SSYRP RS03390
gene id: 1276229:SSYRP_RS03390
uniprot id: R4U6M5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1276229:SSYRP RS04275
gene id: 1276229:SSYRP_RS04275
uniprot id: R4UET0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1276229:SSYRP RS01260
gene id: 1276229:SSYRP_RS01260
uniprot id: R4U378
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1276229:SSYRP RS03275
gene id: 1276229:SSYRP_RS03275
uniprot id: R4UJD8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276229:SSYRP RS04390
gene id: 1276229:SSYRP_RS04390
uniprot id: R4U4P6
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS04320
gene id: 1276229:SSYRP_RS04320
uniprot id: R4UET8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1276229:SSYRP RS03120
gene id: 1276229:SSYRP_RS03120
uniprot id: R4U6I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1276229:SSYRP RS03280
gene id: 1276229:SSYRP_RS03280
uniprot id: R4ULZ2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS04730
gene id: 1276229:SSYRP_RS04730
uniprot id: R4U4V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1276229:SSYRP RS05030
gene id: 1276229:SSYRP_RS05030
uniprot id: R4U514
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS01240
gene id: 1276229:SSYRP_RS01240
uniprot id: R4U5H8
names: Subcellular Location Annotation
messages: Cytoplasm

1276229:SSYRP RS03840
gene id: 1276229:SSYRP_RS03840
uniprot id: R4UEK5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1276229:SSYRP RS03760
gene id: 1276229:SSYRP_RS03760
uniprot id: R4U6T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1276229:SSYRP RS02225
gene id: 1276229:SSYRP_RS02225
uniprot id: R4UDP9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1276229:SSYRP RS01180
gene id: 1276229:SSYRP_RS01180
uniprot id: R4UKN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1276229:SSYRP RS01225
gene id: 1276229:SSYRP_RS01225
uniprot id: R4UI64
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS00105
gene id: 1276229:SSYRP_RS00105
uniprot id: R4U2M3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1276229:SSYRP RS00895
gene id: 1276229:SSYRP_RS00895
uniprot id: R4UKH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS00750
gene id: 1276229:SSYRP_RS00750
uniprot id: R4U2Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1276229:SSYRP RS00930
gene id: 1276229:SSYRP_RS00930
uniprot id: R4U5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1276229:SSYRP RS00035
gene id: 1276229:SSYRP_RS00035
uniprot id: R4U4W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1276229:SSYRP RS00675
gene id: 1276229:SSYRP_RS00675
uniprot id: R4U2X7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1276229:SSYRP RS04920
gene id: 1276229:SSYRP_RS04920
uniprot id: R4UK88
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1276229:SSYRP RS00970
gene id: 1276229:SSYRP_RS00970
uniprot id: R4UKJ2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1276229:SSYRP RS02565
gene id: 1276229:SSYRP_RS02565
uniprot id: R4UDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1276229:SSYRP RS04480
gene id: 1276229:SSYRP_RS04480
uniprot id: R4UJY4
names: Similarity
messages: Belongs to the peptidase M17 family.

1276229:SSYRP RS04235
gene id: 1276229:SSYRP_RS04235
uniprot id: R4UMG2
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03340
gene id: 1276229:SSYRP_RS03340
uniprot id: R4U6L6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1276229:SSYRP RS04950
gene id: 1276229:SSYRP_RS04950
uniprot id: R4UMT8
names: Similarity
messages: Belongs to the IMPACT family.

1276229:SSYRP RS00855
gene id: 1276229:SSYRP_RS00855
uniprot id: R4U5B2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1276229:SSYRP RS05080
gene id: 1276229:SSYRP_RS05080
uniprot id: R4U523
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS03970
gene id: 1276229:SSYRP_RS03970
uniprot id: R4UJR3
names: Similarity
messages: Belongs to the CutC family.

1276229:SSYRP RS04280
gene id: 1276229:SSYRP_RS04280
uniprot id: R4UJV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS05155
gene id: 1276229:SSYRP_RS05155
uniprot id: R4U542
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1276229:SSYRP RS02880
gene id: 1276229:SSYRP_RS02880
uniprot id: R4UJ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1276229:SSYRP RS03625
gene id: 1276229:SSYRP_RS03625
uniprot id: R4UM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1276229:SSYRP RS01320
gene id: 1276229:SSYRP_RS01320
uniprot id: R4UD68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1276229:SSYRP RS01140
gene id: 1276229:SSYRP_RS01140
uniprot id: R4U5G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1276229:SSYRP RS03630
gene id: 1276229:SSYRP_RS03630
uniprot id: R4U4B9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS01855
gene id: 1276229:SSYRP_RS01855
uniprot id: R4UL32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1276229:SSYRP RS00175
gene id: 1276229:SSYRP_RS00175
uniprot id: R4UK38
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1276229:SSYRP RS00605
gene id: 1276229:SSYRP_RS00605
uniprot id: R4U578
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1276229:SSYRP RS01700
gene id: 1276229:SSYRP_RS01700
uniprot id: R4UIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1276229:SSYRP RS01080
gene id: 1276229:SSYRP_RS01080
uniprot id: R4UKL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1276229:SSYRP RS04750
gene id: 1276229:SSYRP_RS04750
uniprot id: R4UMN8
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1276229:SSYRP RS00700
gene id: 1276229:SSYRP_RS00700
uniprot id: R4U2Y1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1276229:SSYRP RS01205
gene id: 1276229:SSYRP_RS01205
uniprot id: R4UKN9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1276229:SSYRP RS02130
gene id: 1276229:SSYRP_RS02130
uniprot id: R4UIK9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1276229:SSYRP RS02720
gene id: 1276229:SSYRP_RS02720
uniprot id: R4U6C8
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS04425
gene id: 1276229:SSYRP_RS04425
uniprot id: R4UEV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1276229:SSYRP RS03990
gene id: 1276229:SSYRP_RS03990
uniprot id: R4UEN5
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03845
gene id: 1276229:SSYRP_RS03845
uniprot id: R4UJP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

1276229:SSYRP RS00825
gene id: 1276229:SSYRP_RS00825
uniprot id: R4U305
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1276229:SSYRP RS00990
gene id: 1276229:SSYRP_RS00990
uniprot id: R4UI25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS00230
gene id: 1276229:SSYRP_RS00230
uniprot id: R4U528
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1276229:SSYRP RS00830
gene id: 1276229:SSYRP_RS00830
uniprot id: R4U5A8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1276229:SSYRP RS01015
gene id: 1276229:SSYRP_RS01015
uniprot id: R4UI29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

1276229:SSYRP RS02615
gene id: 1276229:SSYRP_RS02615
uniprot id: R4UDY8
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03035
gene id: 1276229:SSYRP_RS03035
uniprot id: R4ULV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1276229:SSYRP RS03050
gene id: 1276229:SSYRP_RS03050
uniprot id: R4UE69
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276229:SSYRP RS00730
gene id: 1276229:SSYRP_RS00730
uniprot id: R4U594
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1276229:SSYRP RS04155
gene id: 1276229:SSYRP_RS04155
uniprot id: R4UJT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1276229:SSYRP RS00860
gene id: 1276229:SSYRP_RS00860
uniprot id: R4UCZ4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1276229:SSYRP RS00380
gene id: 1276229:SSYRP_RS00380
uniprot id: R4UK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1276229:SSYRP RS03185
gene id: 1276229:SSYRP_RS03185
uniprot id: R4ULX9
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS03335
gene id: 1276229:SSYRP_RS03335
uniprot id: R4U477
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS00920
gene id: 1276229:SSYRP_RS00920
uniprot id: R4UKI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1276229:SSYRP RS01680
gene id: 1276229:SSYRP_RS01680
uniprot id: R4UKZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1276229:SSYRP RS01245
gene id: 1276229:SSYRP_RS01245
uniprot id: R4UD53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1276229:SSYRP RS03570
gene id: 1276229:SSYRP_RS03570
uniprot id: R4UJJ3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1276229:SSYRP RS02815
gene id: 1276229:SSYRP_RS02815
uniprot id: R4U404
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS01020
gene id: 1276229:SSYRP_RS01020
uniprot id: R4UKK1
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS01345
gene id: 1276229:SSYRP_RS01345
uniprot id: R4UD73
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1276229:SSYRP RS03260
gene id: 1276229:SSYRP_RS03260
uniprot id: R4U467
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

1276229:SSYRP RS00225
gene id: 1276229:SSYRP_RS00225
uniprot id: R4UK50
names: Subcellular Location Annotation
messages: Membrane

1276229:SSYRP RS00705
gene id: 1276229:SSYRP_RS00705
uniprot id: R4U589
names: Similarity
messages: Belongs to the HPrK/P family.

1276229:SSYRP RS04405
gene id: 1276229:SSYRP_RS04405
uniprot id: R4UJX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1276229:SSYRP RS04395
gene id: 1276229:SSYRP_RS04395
uniprot id: R4U730
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1276229:SSYRP RS01935
gene id: 1276229:SSYRP_RS01935
uniprot id: R4UL48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS01215
gene id: 1276229:SSYRP_RS01215
uniprot id: R4U5H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1276229:SSYRP RS00550
gene id: 1276229:SSYRP_RS00550
uniprot id: R4U2V4
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1276229:SSYRP RS01300
gene id: 1276229:SSYRP_RS01300
uniprot id: R4UI77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1276229:SSYRP RS03410
gene id: 1276229:SSYRP_RS03410
uniprot id: R4U488
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1276229:SSYRP RS02525
gene id: 1276229:SSYRP_RS02525
uniprot id: R4ULH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1276229:SSYRP RS01655
gene id: 1276229:SSYRP_RS01655
uniprot id: R4UKY7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1276229:SSYRP RS03085
gene id: 1276229:SSYRP_RS03085
uniprot id: R4ULW4
names: Similarity
messages: Belongs to the ribF family.

1276229:SSYRP RS00125
gene id: 1276229:SSYRP_RS00125
uniprot id: R4UJY5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS01690
gene id: 1276229:SSYRP_RS01690
uniprot id: R4U5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1276229:SSYRP RS00620
gene id: 1276229:SSYRP_RS00620
uniprot id: R4UKC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1276229:SSYRP RS01750
gene id: 1276229:SSYRP_RS01750
uniprot id: R4UIF2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1276229:SSYRP RS01695
gene id: 1276229:SSYRP_RS01695
uniprot id: R4UDE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1276229:SSYRP RS00025
gene id: 1276229:SSYRP_RS00025
uniprot id: R4UJW6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276229:SSYRP RS01870
gene id: 1276229:SSYRP_RS01870
uniprot id: R4UDI1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1276229:SSYRP RS00695
gene id: 1276229:SSYRP_RS00695
uniprot id: R4UKE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).