1276220:STAIW RS05150
gene id: 1276220:STAIW_RS05150
uniprot id: S5LV03
names: Similarity
messages: Belongs to the peptidase M17 family.

1276220:STAIW RS01545
gene id: 1276220:STAIW_RS01545
uniprot id: S5MGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1276220:STAIW RS00440
gene id: 1276220:STAIW_RS00440
uniprot id: S5MAK1
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS02025
gene id: 1276220:STAIW_RS02025
uniprot id: S5LZC3
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS00985
gene id: 1276220:STAIW_RS00985
uniprot id: S5LYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1276220:STAIW RS02220
gene id: 1276220:STAIW_RS02220
uniprot id: S5LTQ4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS03210
gene id: 1276220:STAIW_RS03210
uniprot id: S5LXD8
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS00395
gene id: 1276220:STAIW_RS00395
uniprot id: S5LSX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1276220:STAIW RS02910
gene id: 1276220:STAIW_RS02910
uniprot id: S5LZT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1276220:STAIW RS04295
gene id: 1276220:STAIW_RS04295
uniprot id: S5LUJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276220:STAIW RS01880
gene id: 1276220:STAIW_RS01880
uniprot id: S5LTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1276220:STAIW RS01770
gene id: 1276220:STAIW_RS01770
uniprot id: S5MB61
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1276220:STAIW RS01065
gene id: 1276220:STAIW_RS01065
uniprot id: S5LYW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1276220:STAIW RS04895
gene id: 1276220:STAIW_RS04895
uniprot id: S5LYC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1276220:STAIW RS00445
gene id: 1276220:STAIW_RS00445
uniprot id: S5LSY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1276220:STAIW RS01700
gene id: 1276220:STAIW_RS01700
uniprot id: S5MB49
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1276220:STAIW RS04910
gene id: 1276220:STAIW_RS04910
uniprot id: S5LUV9
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS05225
gene id: 1276220:STAIW_RS05225
uniprot id: S5LV23
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1276220:STAIW RS04725
gene id: 1276220:STAIW_RS04725
uniprot id: S5MI33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1276220:STAIW RS01145
gene id: 1276220:STAIW_RS01145
uniprot id: S5MAV4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1276220:STAIW RS00490
gene id: 1276220:STAIW_RS00490
uniprot id: S5LYP8
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS00230
gene id: 1276220:STAIW_RS00230
uniprot id: S5LSV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1276220:STAIW RS04060
gene id: 1276220:STAIW_RS04060
uniprot id: S5MHR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1276220:STAIW RS03755
gene id: 1276220:STAIW_RS03755
uniprot id: S5M043
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1276220:STAIW RS00370
gene id: 1276220:STAIW_RS00370
uniprot id: S5LSX3
names: Similarity
messages: Belongs to the Lgt family.

1276220:STAIW RS03975
gene id: 1276220:STAIW_RS03975
uniprot id: S5MHQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1276220:STAIW RS02325
gene id: 1276220:STAIW_RS02325
uniprot id: S5MGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1276220:STAIW RS02140
gene id: 1276220:STAIW_RS02140
uniprot id: S5LZE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS02485
gene id: 1276220:STAIW_RS02485
uniprot id: S5LWY2
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS00710
gene id: 1276220:STAIW_RS00710
uniprot id: S5LW61
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1276220:STAIW RS00805
gene id: 1276220:STAIW_RS00805
uniprot id: S5LYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276220:STAIW RS01960
gene id: 1276220:STAIW_RS01960
uniprot id: S5LTK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1276220:STAIW RS04200
gene id: 1276220:STAIW_RS04200
uniprot id: S5MCK0
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS00735
gene id: 1276220:STAIW_RS00735
uniprot id: S5LT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276220:STAIW RS02875
gene id: 1276220:STAIW_RS02875
uniprot id: S5MH97
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1276220:STAIW RS05300
gene id: 1276220:STAIW_RS05300
uniprot id: S5MIC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1276220:STAIW RS04540
gene id: 1276220:STAIW_RS04540
uniprot id: S5MHZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1276220:STAIW RS00410
gene id: 1276220:STAIW_RS00410
uniprot id: S5LYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1276220:STAIW RS03010
gene id: 1276220:STAIW_RS03010
uniprot id: S5LZU3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1276220:STAIW RS02265
gene id: 1276220:STAIW_RS02265
uniprot id: S5LTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1276220:STAIW RS04380
gene id: 1276220:STAIW_RS04380
uniprot id: S5MCN8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1276220:STAIW RS02135
gene id: 1276220:STAIW_RS02135
uniprot id: S5LWQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1276220:STAIW RS00880
gene id: 1276220:STAIW_RS00880
uniprot id: S5LW71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

1276220:STAIW RS03625
gene id: 1276220:STAIW_RS03625
uniprot id: S5MC95
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276220:STAIW RS05255
gene id: 1276220:STAIW_RS05255
uniprot id: S5LYL7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1276220:STAIW RS04905
gene id: 1276220:STAIW_RS04905
uniprot id: S5MCY6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS04505
gene id: 1276220:STAIW_RS04505
uniprot id: S5MCR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1276220:STAIW RS03620
gene id: 1276220:STAIW_RS03620
uniprot id: S5M021
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS00695
gene id: 1276220:STAIW_RS00695
uniprot id: S5MAP6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1276220:STAIW RS00225
gene id: 1276220:STAIW_RS00225
uniprot id: S5MAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1276220:STAIW RS00980
gene id: 1276220:STAIW_RS00980
uniprot id: S5LW89
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS05350
gene id: 1276220:STAIW_RS05350
uniprot id: S5MIE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1276220:STAIW RS04425
gene id: 1276220:STAIW_RS04425
uniprot id: S5M0H1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1276220:STAIW RS04750
gene id: 1276220:STAIW_RS04750
uniprot id: S5MI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1276220:STAIW RS04890
gene id: 1276220:STAIW_RS04890
uniprot id: S5MI61
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1276220:STAIW RS04565
gene id: 1276220:STAIW_RS04565
uniprot id: S5LUN7
names: Similarity
messages: Belongs to the asp23 family.

1276220:STAIW RS04980
gene id: 1276220:STAIW_RS04980
uniprot id: S5MD09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1276220:STAIW RS04480
gene id: 1276220:STAIW_RS04480
uniprot id: S5MCQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1276220:STAIW RS01795
gene id: 1276220:STAIW_RS01795
uniprot id: S5MB68
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS01125
gene id: 1276220:STAIW_RS01125
uniprot id: S5MGA7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS05005
gene id: 1276220:STAIW_RS05005
uniprot id: S5MD14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1276220:STAIW RS01920
gene id: 1276220:STAIW_RS01920
uniprot id: S5LZA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1276220:STAIW RS01080
gene id: 1276220:STAIW_RS01080
uniprot id: S5MGA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1276220:STAIW RS05040
gene id: 1276220:STAIW_RS05040
uniprot id: S5MI89
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1276220:STAIW RS01020
gene id: 1276220:STAIW_RS01020
uniprot id: S5MAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1276220:STAIW RS01350
gene id: 1276220:STAIW_RS01350
uniprot id: S5LTA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1276220:STAIW RS05045
gene id: 1276220:STAIW_RS05045
uniprot id: S5LYF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1276220:STAIW RS04625
gene id: 1276220:STAIW_RS04625
uniprot id: S5MI13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1276220:STAIW RS01305
gene id: 1276220:STAIW_RS01305
uniprot id: S5MGD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1276220:STAIW RS05275
gene id: 1276220:STAIW_RS05275
uniprot id: S5MIC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276220:STAIW RS01330
gene id: 1276220:STAIW_RS01330
uniprot id: S5MGE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1276220:STAIW RS02805
gene id: 1276220:STAIW_RS02805
uniprot id: S5LZS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1276220:STAIW RS03330
gene id: 1276220:STAIW_RS03330
uniprot id: S5LZY7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1276220:STAIW RS04935
gene id: 1276220:STAIW_RS04935
uniprot id: S5LUW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1276220:STAIW RS00165
gene id: 1276220:STAIW_RS00165
uniprot id: S5LVX1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1276220:STAIW RS00240
gene id: 1276220:STAIW_RS00240
uniprot id: S5LVY2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1276220:STAIW RS04885
gene id: 1276220:STAIW_RS04885
uniprot id: S5LUV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS01280
gene id: 1276220:STAIW_RS01280
uniprot id: S5MGD1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1276220:STAIW RS05170
gene id: 1276220:STAIW_RS05170
uniprot id: S5MD49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1276220:STAIW RS05580
gene id: 1276220:STAIW_RS05580
uniprot id: S5MAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276220:STAIW RS00455
gene id: 1276220:STAIW_RS00455
uniprot id: S5LW16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1276220:STAIW RS00390
gene id: 1276220:STAIW_RS00390
uniprot id: S5MAJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1276220:STAIW RS04970
gene id: 1276220:STAIW_RS04970
uniprot id: S5LYD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1276220:STAIW RS04325
gene id: 1276220:STAIW_RS04325
uniprot id: S5MHV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1276220:STAIW RS00400
gene id: 1276220:STAIW_RS00400
uniprot id: S5MFY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1276220:STAIW RS04900
gene id: 1276220:STAIW_RS04900
uniprot id: S5M0P7
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS02685
gene id: 1276220:STAIW_RS02685
uniprot id: S5MBN1
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS05030
gene id: 1276220:STAIW_RS05030
uniprot id: S5MD21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1276220:STAIW RS02970
gene id: 1276220:STAIW_RS02970
uniprot id: S5LU25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1276220:STAIW RS03660
gene id: 1276220:STAIW_RS03660
uniprot id: S5MC98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1276220:STAIW RS04290
gene id: 1276220:STAIW_RS04290
uniprot id: S5MCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1276220:STAIW RS03505
gene id: 1276220:STAIW_RS03505
uniprot id: S5MHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276220:STAIW RS01005
gene id: 1276220:STAIW_RS01005
uniprot id: S5MG88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1276220:STAIW RS05145
gene id: 1276220:STAIW_RS05145
uniprot id: S5MD44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1276220:STAIW RS04470
gene id: 1276220:STAIW_RS04470
uniprot id: S5LY22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1276220:STAIW RS01265
gene id: 1276220:STAIW_RS01265
uniprot id: S5LYZ5
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1276220:STAIW RS05385
gene id: 1276220:STAIW_RS05385
uniprot id: S5MDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1276220:STAIW RS04685
gene id: 1276220:STAIW_RS04685
uniprot id: S5M0L5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1276220:STAIW RS04995
gene id: 1276220:STAIW_RS04995
uniprot id: S5LYE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1276220:STAIW RS01620
gene id: 1276220:STAIW_RS01620
uniprot id: S5LZ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1276220:STAIW RS05430
gene id: 1276220:STAIW_RS05430
uniprot id: S5M112
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1276220:STAIW RS05625
gene id: 1276220:STAIW_RS05625
uniprot id: S5LWH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1276220:STAIW RS05415
gene id: 1276220:STAIW_RS05415
uniprot id: S5LV80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS04735
gene id: 1276220:STAIW_RS04735
uniprot id: S5M0M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1276220:STAIW RS04235
gene id: 1276220:STAIW_RS04235
uniprot id: S5MHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276220:STAIW RS00885
gene id: 1276220:STAIW_RS00885
uniprot id: S5LYU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS04265
gene id: 1276220:STAIW_RS04265
uniprot id: S5M0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276220:STAIW RS01490
gene id: 1276220:STAIW_RS01490
uniprot id: S5MGH9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1276220:STAIW RS04195
gene id: 1276220:STAIW_RS04195
uniprot id: S5M0C7
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS04960
gene id: 1276220:STAIW_RS04960
uniprot id: S5LUW7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1276220:STAIW RS03955
gene id: 1276220:STAIW_RS03955
uniprot id: S5LXT4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1276220:STAIW RS05125
gene id: 1276220:STAIW_RS05125
uniprot id: S5LUZ7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1276220:STAIW RS05305
gene id: 1276220:STAIW_RS05305
uniprot id: S5LYN5
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS01455
gene id: 1276220:STAIW_RS01455
uniprot id: S5LTC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS03380
gene id: 1276220:STAIW_RS03380
uniprot id: S5MHI3
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS04965
gene id: 1276220:STAIW_RS04965
uniprot id: S5MI75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1276220:STAIW RS02015
gene id: 1276220:STAIW_RS02015
uniprot id: S5MGT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1276220:STAIW RS00435
gene id: 1276220:STAIW_RS00435
uniprot id: S5LYP0
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS00505
gene id: 1276220:STAIW_RS00505
uniprot id: S5MG05
names: Subcellular Location Annotation
messages: Cytoplasm

1276220:STAIW RS00450
gene id: 1276220:STAIW_RS00450
uniprot id: S5MFZ5
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1276220:STAIW RS03455
gene id: 1276220:STAIW_RS03455
uniprot id: S5LZZ9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1276220:STAIW RS05850
gene id: 1276220:STAIW_RS05850
uniprot id: S5LYE8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1276220:STAIW RS03045
gene id: 1276220:STAIW_RS03045
uniprot id: S5MBY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1276220:STAIW RS00310
gene id: 1276220:STAIW_RS00310
uniprot id: S5LSW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1276220:STAIW RS00040
gene id: 1276220:STAIW_RS00040
uniprot id: S5MFS2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1276220:STAIW RS00970
gene id: 1276220:STAIW_RS00970
uniprot id: S5LT53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1276220:STAIW RS00080
gene id: 1276220:STAIW_RS00080
uniprot id: S5LST1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1276220:STAIW RS05265
gene id: 1276220:STAIW_RS05265
uniprot id: S5MD66
names: Similarity
messages: Belongs to the RpoE family.

1276220:STAIW RS01540
gene id: 1276220:STAIW_RS01540
uniprot id: S5LTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1276220:STAIW RS04020
gene id: 1276220:STAIW_RS04020
uniprot id: S5LUF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1276220:STAIW RS02210
gene id: 1276220:STAIW_RS02210
uniprot id: S5LZF8
names: Similarity
messages: Belongs to the ParB family.

1276220:STAIW RS01345
gene id: 1276220:STAIW_RS01345
uniprot id: S5MAY9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS00790
gene id: 1276220:STAIW_RS00790
uniprot id: S5MAQ7
names: Similarity
messages: Belongs to the thioredoxin family.

1276220:STAIW RS04055
gene id: 1276220:STAIW_RS04055
uniprot id: S5LUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1276220:STAIW RS03705
gene id: 1276220:STAIW_RS03705
uniprot id: S5M038
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1276220:STAIW RS00170
gene id: 1276220:STAIW_RS00170
uniprot id: S5LYK6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1276220:STAIW RS05110
gene id: 1276220:STAIW_RS05110
uniprot id: S5LYH0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1276220:STAIW RS00210
gene id: 1276220:STAIW_RS00210
uniprot id: S5MFV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1276220:STAIW RS01120
gene id: 1276220:STAIW_RS01120
uniprot id: S5LT72
names: Similarity
messages: Belongs to the pyruvate kinase family.

1276220:STAIW RS04605
gene id: 1276220:STAIW_RS04605
uniprot id: S5LY53
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1276220:STAIW RS04415
gene id: 1276220:STAIW_RS04415
uniprot id: S5MHX4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1276220:STAIW RS04155
gene id: 1276220:STAIW_RS04155
uniprot id: S5LUH0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1276220:STAIW RS01715
gene id: 1276220:STAIW_RS01715
uniprot id: S5LWJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS05685
gene id: 1276220:STAIW_RS05685
uniprot id: S5M016
names: Similarity
messages: Belongs to the UPF0236 family.

1276220:STAIW RS03435
gene id: 1276220:STAIW_RS03435
uniprot id: S5MC68
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS05035
gene id: 1276220:STAIW_RS05035
uniprot id: S5LUY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1276220:STAIW RS01565
gene id: 1276220:STAIW_RS01565
uniprot id: S5LTE1
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS01910
gene id: 1276220:STAIW_RS01910
uniprot id: S5MGR0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1276220:STAIW RS05720
gene id: 1276220:STAIW_RS05720
uniprot id: S5M0A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1276220:STAIW RS05165
gene id: 1276220:STAIW_RS05165
uniprot id: S5M0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1276220:STAIW RS01690
gene id: 1276220:STAIW_RS01690
uniprot id: S5LWI9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1276220:STAIW RS02120
gene id: 1276220:STAIW_RS02120
uniprot id: S5MBC4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1276220:STAIW RS04545
gene id: 1276220:STAIW_RS04545
uniprot id: S5LY40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1276220:STAIW RS04765
gene id: 1276220:STAIW_RS04765
uniprot id: S5LUT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1276220:STAIW RS02030
gene id: 1276220:STAIW_RS02030
uniprot id: S5MBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1276220:STAIW RS01505
gene id: 1276220:STAIW_RS01505
uniprot id: S5LZ34
names: Subcellular Location Annotation
messages: Cytoplasm

1276220:STAIW RS00955
gene id: 1276220:STAIW_RS00955
uniprot id: S5LW83
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS00465
gene id: 1276220:STAIW_RS00465
uniprot id: S5MAK6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1276220:STAIW RS05175
gene id: 1276220:STAIW_RS05175
uniprot id: S5LV10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1276220:STAIW RS02405
gene id: 1276220:STAIW_RS02405
uniprot id: S5LZJ5
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS01440
gene id: 1276220:STAIW_RS01440
uniprot id: S5LWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1276220:STAIW RS03225
gene id: 1276220:STAIW_RS03225
uniprot id: S5LU58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1276220:STAIW RS04570
gene id: 1276220:STAIW_RS04570
uniprot id: S5MI03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1276220:STAIW RS04230
gene id: 1276220:STAIW_RS04230
uniprot id: S5LUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276220:STAIW RS04130
gene id: 1276220:STAIW_RS04130
uniprot id: S5LUG7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1276220:STAIW RS04400
gene id: 1276220:STAIW_RS04400
uniprot id: S5M0G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS02415
gene id: 1276220:STAIW_RS02415
uniprot id: S5LTU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1276220:STAIW RS03035
gene id: 1276220:STAIW_RS03035
uniprot id: S5LX90
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1276220:STAIW RS04150
gene id: 1276220:STAIW_RS04150
uniprot id: S5MCI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1276220:STAIW RS01640
gene id: 1276220:STAIW_RS01640
uniprot id: S5LWH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1276220:STAIW RS01420
gene id: 1276220:STAIW_RS01420
uniprot id: S5MB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1276220:STAIW RS02395
gene id: 1276220:STAIW_RS02395
uniprot id: S5MH04
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1276220:STAIW RS00775
gene id: 1276220:STAIW_RS00775
uniprot id: S5LW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1276220:STAIW RS04135
gene id: 1276220:STAIW_RS04135
uniprot id: S5MHS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS04350
gene id: 1276220:STAIW_RS04350
uniprot id: S5MHW4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1276220:STAIW RS03145
gene id: 1276220:STAIW_RS03145
uniprot id: S5LZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1276220:STAIW RS04085
gene id: 1276220:STAIW_RS04085
uniprot id: S5MHS0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1276220:STAIW RS00045
gene id: 1276220:STAIW_RS00045
uniprot id: S5LVV3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1276220:STAIW RS00215
gene id: 1276220:STAIW_RS00215
uniprot id: S5LVX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1276220:STAIW RS05355
gene id: 1276220:STAIW_RS05355
uniprot id: S5LYQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1276220:STAIW RS05025
gene id: 1276220:STAIW_RS05025
uniprot id: S5M0S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1276220:STAIW RS00280
gene id: 1276220:STAIW_RS00280
uniprot id: S5MAH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1276220:STAIW RS00960
gene id: 1276220:STAIW_RS00960
uniprot id: S5LYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1276220:STAIW RS04120
gene id: 1276220:STAIW_RS04120
uniprot id: S5M0B1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1276220:STAIW RS03510
gene id: 1276220:STAIW_RS03510
uniprot id: S5LXJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276220:STAIW RS04985
gene id: 1276220:STAIW_RS04985
uniprot id: S5LUX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1276220:STAIW RS04475
gene id: 1276220:STAIW_RS04475
uniprot id: S5M0H9
names: Similarity
messages: Belongs to the CutC family.

1276220:STAIW RS05335
gene id: 1276220:STAIW_RS05335
uniprot id: S5M0Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276220:STAIW RS05290
gene id: 1276220:STAIW_RS05290
uniprot id: S5MD70
names: Similarity
messages: Belongs to the ParB family.

1276220:STAIW RS03555
gene id: 1276220:STAIW_RS03555
uniprot id: S5M013
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1276220:STAIW RS05015
gene id: 1276220:STAIW_RS05015
uniprot id: S5MI84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1276220:STAIW RS05060
gene id: 1276220:STAIW_RS05060
uniprot id: S5LUY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1276220:STAIW RS05330
gene id: 1276220:STAIW_RS05330
uniprot id: S5LYP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1276220:STAIW RS00110
gene id: 1276220:STAIW_RS00110
uniprot id: S5MFT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1276220:STAIW RS02235
gene id: 1276220:STAIW_RS02235
uniprot id: S5MBF3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1276220:STAIW RS02950
gene id: 1276220:STAIW_RS02950
uniprot id: S5MHA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1276220:STAIW RS01550
gene id: 1276220:STAIW_RS01550
uniprot id: S5LWG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS03970
gene id: 1276220:STAIW_RS03970
uniprot id: S5LUE5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1276220:STAIW RS01585
gene id: 1276220:STAIW_RS01585
uniprot id: S5LWG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1276220:STAIW RS04485
gene id: 1276220:STAIW_RS04485
uniprot id: S5LUM1
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276220:STAIW RS03300
gene id: 1276220:STAIW_RS03300
uniprot id: S5LZY4
names: Similarity
messages: Belongs to the UPF0236 family.

1276220:STAIW RS05115
gene id: 1276220:STAIW_RS05115
uniprot id: S5M0U0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1276220:STAIW RS01240
gene id: 1276220:STAIW_RS01240
uniprot id: S5LYZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS00115
gene id: 1276220:STAIW_RS00115
uniprot id: S5LVW3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1276220:STAIW RS02320
gene id: 1276220:STAIW_RS02320
uniprot id: S5LTS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1276220:STAIW RS03950
gene id: 1276220:STAIW_RS03950
uniprot id: S5MHQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1276220:STAIW RS00570
gene id: 1276220:STAIW_RS00570
uniprot id: S5LYQ9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1276220:STAIW RS04865
gene id: 1276220:STAIW_RS04865
uniprot id: S5MI57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1276220:STAIW RS04320
gene id: 1276220:STAIW_RS04320
uniprot id: S5LUJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1276220:STAIW RS04940
gene id: 1276220:STAIW_RS04940
uniprot id: S5MI70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1276220:STAIW RS04210
gene id: 1276220:STAIW_RS04210
uniprot id: S5MHT8
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276220:STAIW RS04705
gene id: 1276220:STAIW_RS04705
uniprot id: S5LY82
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1276220:STAIW RS01480
gene id: 1276220:STAIW_RS01480
uniprot id: S5MB12
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1276220:STAIW RS01955
gene id: 1276220:STAIW_RS01955
uniprot id: S5MB95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1276220:STAIW RS01390
gene id: 1276220:STAIW_RS01390
uniprot id: S5LZ16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1276220:STAIW RS05100
gene id: 1276220:STAIW_RS05100
uniprot id: S5LUZ1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1276220:STAIW RS01695
gene id: 1276220:STAIW_RS01695
uniprot id: S5LZ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1276220:STAIW RS00305
gene id: 1276220:STAIW_RS00305
uniprot id: S5MAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1276220:STAIW RS00270
gene id: 1276220:STAIW_RS00270
uniprot id: S5LVY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1276220:STAIW RS04555
gene id: 1276220:STAIW_RS04555
uniprot id: S5M0J4
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS02940
gene id: 1276220:STAIW_RS02940
uniprot id: S5MBV0
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1276220:STAIW RS02765
gene id: 1276220:STAIW_RS02765
uniprot id: S5MBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1276220:STAIW RS00010
gene id: 1276220:STAIW_RS00010
uniprot id: S5LSR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase.

1276220:STAIW RS01475
gene id: 1276220:STAIW_RS01475
uniprot id: S5LZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1276220:STAIW RS01665
gene id: 1276220:STAIW_RS01665
uniprot id: S5LWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1276220:STAIW RS04700
gene id: 1276220:STAIW_RS04700
uniprot id: S5MI28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276220:STAIW RS04950
gene id: 1276220:STAIW_RS04950
uniprot id: S5M0Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1276220:STAIW RS00060
gene id: 1276220:STAIW_RS00060
uniprot id: S5LSS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1276220:STAIW RS01220
gene id: 1276220:STAIW_RS01220
uniprot id: S5MAW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1276220:STAIW RS04015
gene id: 1276220:STAIW_RS04015
uniprot id: S5MCG0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1276220:STAIW RS00375
gene id: 1276220:STAIW_RS00375
uniprot id: S5MFX8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1276220:STAIW RS00415
gene id: 1276220:STAIW_RS00415
uniprot id: S5MAJ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS01875
gene id: 1276220:STAIW_RS01875
uniprot id: S5MB79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1276220:STAIW RS00015
gene id: 1276220:STAIW_RS00015
uniprot id: S5MFR8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1276220:STAIW RS04175
gene id: 1276220:STAIW_RS04175
uniprot id: S5MCJ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1276220:STAIW RS01485
gene id: 1276220:STAIW_RS01485
uniprot id: S5LTC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1276220:STAIW RS04590
gene id: 1276220:STAIW_RS04590
uniprot id: S5MCS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1276220:STAIW RS05390
gene id: 1276220:STAIW_RS05390
uniprot id: S5LV76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm

1276220:STAIW RS00875
gene id: 1276220:STAIW_RS00875
uniprot id: S5MG68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS05220
gene id: 1276220:STAIW_RS05220
uniprot id: S5MD56
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1276220:STAIW RS00175
gene id: 1276220:STAIW_RS00175
uniprot id: S5MAF6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1276220:STAIW RS01525
gene id: 1276220:STAIW_RS01525
uniprot id: S5LWG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1276220:STAIW RS04930
gene id: 1276220:STAIW_RS04930
uniprot id: S5MCZ4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1276220:STAIW RS00470
gene id: 1276220:STAIW_RS00470
uniprot id: S5LSY6
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276220:STAIW RS05010
gene id: 1276220:STAIW_RS05010
uniprot id: S5LUX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1276220:STAIW RS00005
gene id: 1276220:STAIW_RS00005
uniprot id: S5MAC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1276220:STAIW RS02375
gene id: 1276220:STAIW_RS02375
uniprot id: S5LWW6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1276220:STAIW RS04825
gene id: 1276220:STAIW_RS04825
uniprot id: S5LUU1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1276220:STAIW RS01765
gene id: 1276220:STAIW_RS01765
uniprot id: S5LZ80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1276220:STAIW RS05405
gene id: 1276220:STAIW_RS05405
uniprot id: S5M108
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS00365
gene id: 1276220:STAIW_RS00365
uniprot id: S5MAI8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1276220:STAIW RS05160
gene id: 1276220:STAIW_RS05160
uniprot id: S5LYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1276220:STAIW RS03905
gene id: 1276220:STAIW_RS03905
uniprot id: S5LUD6
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS03750
gene id: 1276220:STAIW_RS03750
uniprot id: S5LXN3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1276220:STAIW RS00035
gene id: 1276220:STAIW_RS00035
uniprot id: S5LSS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1276220:STAIW RS03985
gene id: 1276220:STAIW_RS03985
uniprot id: S5M093
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1276220:STAIW RS05050
gene id: 1276220:STAIW_RS05050
uniprot id: S5M0S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1276220:STAIW RS00180
gene id: 1276220:STAIW_RS00180
uniprot id: S5LSU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1276220:STAIW RS04870
gene id: 1276220:STAIW_RS04870
uniprot id: S5LYB5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1276220:STAIW RS00235
gene id: 1276220:STAIW_RS00235
uniprot id: S5MFV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1276220:STAIW RS02350
gene id: 1276220:STAIW_RS02350
uniprot id: S5MGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1276220:STAIW RS05395
gene id: 1276220:STAIW_RS05395
uniprot id: S5MIG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1276220:STAIW RS00300
gene id: 1276220:STAIW_RS00300
uniprot id: S5LYM2
names: Similarity
messages: Belongs to the IMPACT family.

1276220:STAIW RS04010
gene id: 1276220:STAIW_RS04010
uniprot id: S5M099
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1276220:STAIW RS00720
gene id: 1276220:STAIW_RS00720
uniprot id: S5MAQ1
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS02515
gene id: 1276220:STAIW_RS02515
uniprot id: S5LZK9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1276220:STAIW RS01225
gene id: 1276220:STAIW_RS01225
uniprot id: S5LT85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1276220:STAIW RS03095
gene id: 1276220:STAIW_RS03095
uniprot id: S5LXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1276220:STAIW RS00480
gene id: 1276220:STAIW_RS00480
uniprot id: S5MG01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1276220:STAIW RS01110
gene id: 1276220:STAIW_RS01110
uniprot id: S5LYX3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS01645
gene id: 1276220:STAIW_RS01645
uniprot id: S5LZ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1276220:STAIW RS00245
gene id: 1276220:STAIW_RS00245
uniprot id: S5LYL6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1276220:STAIW RS00595
gene id: 1276220:STAIW_RS00595
uniprot id: S5LYR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1276220:STAIW RS05065
gene id: 1276220:STAIW_RS05065
uniprot id: S5MI93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1276220:STAIW RS04310
gene id: 1276220:STAIW_RS04310
uniprot id: S5M0F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1276220:STAIW RS03650
gene id: 1276220:STAIW_RS03650
uniprot id: S5LXL4
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1276220:STAIW RS01930
gene id: 1276220:STAIW_RS01930
uniprot id: S5LTK3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276220:STAIW RS05230
gene id: 1276220:STAIW_RS05230
uniprot id: S5MIB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1276220:STAIW RS03325
gene id: 1276220:STAIW_RS03325
uniprot id: S5LXG3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1276220:STAIW RS04165
gene id: 1276220:STAIW_RS04165
uniprot id: S5LXW4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1276220:STAIW RS01230
gene id: 1276220:STAIW_RS01230
uniprot id: S5MGC0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1276220:STAIW RS05260
gene id: 1276220:STAIW_RS05260
uniprot id: S5M0X1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS04955
gene id: 1276220:STAIW_RS04955
uniprot id: S5MD02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1276220:STAIW RS01735
gene id: 1276220:STAIW_RS01735
uniprot id: S5MGM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1276220:STAIW RS02870
gene id: 1276220:STAIW_RS02870
uniprot id: S5LU10
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS05400
gene id: 1276220:STAIW_RS05400
uniprot id: S5LYR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS01555
gene id: 1276220:STAIW_RS01555
uniprot id: S5LZ45
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1276220:STAIW RS00360
gene id: 1276220:STAIW_RS00360
uniprot id: S5LYM9
names: Similarity
messages: Belongs to the Lgt family.

1276220:STAIW RS00275
gene id: 1276220:STAIW_RS00275
uniprot id: S5LYL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1276220:STAIW RS01325
gene id: 1276220:STAIW_RS01325
uniprot id: S5LTA2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1276220:STAIW RS01860
gene id: 1276220:STAIW_RS01860
uniprot id: S5MGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1276220:STAIW RS01890
gene id: 1276220:STAIW_RS01890
uniprot id: S5LWM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1276220:STAIW RS04050
gene id: 1276220:STAIW_RS04050
uniprot id: S5MCG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1276220:STAIW RS00355
gene id: 1276220:STAIW_RS00355
uniprot id: S5LVZ6
names: Similarity
messages: Belongs to the HPrK/P family.

1276220:STAIW RS00285
gene id: 1276220:STAIW_RS00285
uniprot id: S5LSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1276220:STAIW RS00135
gene id: 1276220:STAIW_RS00135
uniprot id: S5MFT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1276220:STAIW RS02945
gene id: 1276220:STAIW_RS02945
uniprot id: S5LU21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1276220:STAIW RS00935
gene id: 1276220:STAIW_RS00935
uniprot id: S5LYU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1276220:STAIW RS04675
gene id: 1276220:STAIW_RS04675
uniprot id: S5MI22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1276220:STAIW RS01130
gene id: 1276220:STAIW_RS01130
uniprot id: S5LWA7
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS04435
gene id: 1276220:STAIW_RS04435
uniprot id: S5LUL4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1276220:STAIW RS04745
gene id: 1276220:STAIW_RS04745
uniprot id: S5LUS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276220:STAIW RS05055
gene id: 1276220:STAIW_RS05055
uniprot id: S5MD26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1276220:STAIW RS00105
gene id: 1276220:STAIW_RS00105
uniprot id: S5LST4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS01705
gene id: 1276220:STAIW_RS01705
uniprot id: S5LTG4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1276220:STAIW RS01425
gene id: 1276220:STAIW_RS01425
uniprot id: S5LTC0
names: Similarity
messages: Belongs to the peptidase M13 family.

1276220:STAIW RS00565
gene id: 1276220:STAIW_RS00565
uniprot id: S5LW35
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1276220:STAIW RS01625
gene id: 1276220:STAIW_RS01625
uniprot id: S5MB32
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1276220:STAIW RS02115
gene id: 1276220:STAIW_RS02115
uniprot id: S5LZD8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1276220:STAIW RS01010
gene id: 1276220:STAIW_RS01010
uniprot id: S5LW92
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276220:STAIW RS04065
gene id: 1276220:STAIW_RS04065
uniprot id: S5LXV1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS03770
gene id: 1276220:STAIW_RS03770
uniprot id: S5MHN3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1276220:STAIW RS01070
gene id: 1276220:STAIW_RS01070
uniprot id: S5MAU3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1276220:STAIW RS02645
gene id: 1276220:STAIW_RS02645
uniprot id: S5MH62
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1276220:STAIW RS04880
gene id: 1276220:STAIW_RS04880
uniprot id: S5MCX6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276220:STAIW RS03425
gene id: 1276220:STAIW_RS03425
uniprot id: S5LXH7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1276220:STAIW RS00500
gene id: 1276220:STAIW_RS00500
uniprot id: S5LSY9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1276220:STAIW RS00020
gene id: 1276220:STAIW_RS00020
uniprot id: S5LVU9
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1276220:STAIW RS04345
gene id: 1276220:STAIW_RS04345
uniprot id: S5LUK3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1276220:STAIW RS01115
gene id: 1276220:STAIW_RS01115
uniprot id: S5MAU9
names: Similarity
messages: Belongs to the pyruvate kinase family.

1276220:STAIW RS04925
gene id: 1276220:STAIW_RS04925
uniprot id: S5M0Q1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1276220:STAIW RS05345
gene id: 1276220:STAIW_RS05345
uniprot id: S5LV60
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1276220:STAIW RS04525
gene id: 1276220:STAIW_RS04525
uniprot id: S5M0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

1276220:STAIW RS00255
gene id: 1276220:STAIW_RS00255
uniprot id: S5MAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

1276220:STAIW RS04335
gene id: 1276220:STAIW_RS04335
uniprot id: S5M0F8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1276220:STAIW RS02930
gene id: 1276220:STAIW_RS02930
uniprot id: S5LX69
names: Similarity
messages: Belongs to the TlyA family.

1276220:STAIW RS05285
gene id: 1276220:STAIW_RS05285
uniprot id: S5M0X6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1276220:STAIW RS04945
gene id: 1276220:STAIW_RS04945
uniprot id: S5LYD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1276220:STAIW RS00085
gene id: 1276220:STAIW_RS00085
uniprot id: S5MFS9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1276220:STAIW RS05095
gene id: 1276220:STAIW_RS05095
uniprot id: S5MD34
names: Subcellular Location Annotation
messages: Membrane

1276220:STAIW RS05715
gene id: 1276220:STAIW_RS05715
uniprot id: S5LXT9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1276220:STAIW RS01530
gene id: 1276220:STAIW_RS01530
uniprot id: S5LZ38
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276220:STAIW RS05375
gene id: 1276220:STAIW_RS05375
uniprot id: S5LYR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1276220:STAIW RS05435
gene id: 1276220:STAIW_RS05435
uniprot id: S5MDA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1276220:STAIW RS02035
gene id: 1276220:STAIW_RS02035
uniprot id: S5LTM1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1276220:STAIW RS00265
gene id: 1276220:STAIW_RS00265
uniprot id: S5MFV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1276220:STAIW RS00145
gene id: 1276220:STAIW_RS00145
uniprot id: S5LYK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1276220:STAIW RS04875
gene id: 1276220:STAIW_RS04875
uniprot id: S5M0P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1276220:STAIW RS01140
gene id: 1276220:STAIW_RS01140
uniprot id: S5LYX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1276220:STAIW RS03110
gene id: 1276220:STAIW_RS03110
uniprot id: S5LU41
names: Similarity
messages: Belongs to the UPF0236 family.