1273541:Pyrde RS00265
gene id: 1273541:Pyrde_RS00265
uniprot id: A0A0P0MZT9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1273541:Pyrde RS08190
gene id: 1273541:Pyrde_RS08190
uniprot id: A0A0P0N4V3
names: Subunit
messages: Homodimer.

1273541:Pyrde RS03950
gene id: 1273541:Pyrde_RS03950
uniprot id: A0A0P0N3U2
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS07355
gene id: 1273541:Pyrde_RS07355
uniprot id: A0A0P0N446
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1273541:Pyrde RS04130
gene id: 1273541:Pyrde_RS04130
uniprot id: A0A0P0N317
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1273541:Pyrde RS08410
gene id: 1273541:Pyrde_RS08410
uniprot id: A0A0N7JDB2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

1273541:Pyrde RS03110
gene id: 1273541:Pyrde_RS03110
uniprot id: A0A0N7JCY1
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS10220
gene id: 1273541:Pyrde_RS10220
uniprot id: A0A0P0N621
names: Similarity
messages: Belongs to the MEMO1 family.

1273541:Pyrde RS07840
gene id: 1273541:Pyrde_RS07840
uniprot id: A0A211YQQ5
names: Caution
names: Similarity
messages: Belongs to the UPF0166 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01745
gene id: 1273541:Pyrde_RS01745
uniprot id: A0A211YM93
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01475
gene id: 1273541:Pyrde_RS01475
uniprot id: A0A0P0N2T2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1273541:Pyrde RS00675
gene id: 1273541:Pyrde_RS00675
uniprot id: A0A211YN47
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04655
gene id: 1273541:Pyrde_RS04655
uniprot id: A0A211YQZ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02410
gene id: 1273541:Pyrde_RS02410
uniprot id: A0A211YLV3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06305
gene id: 1273541:Pyrde_RS06305
uniprot id: A0A211YSA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS00645
gene id: 1273541:Pyrde_RS00645
uniprot id: A0A0P0N1X2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

1273541:Pyrde RS05445
gene id: 1273541:Pyrde_RS05445
uniprot id: A0A211YQI9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01560
gene id: 1273541:Pyrde_RS01560
uniprot id: A0A211YND1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04625
gene id: 1273541:Pyrde_RS04625
uniprot id: A0A211YQW2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01925
gene id: 1273541:Pyrde_RS01925
uniprot id: A0A211YLT3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02710
gene id: 1273541:Pyrde_RS02710
uniprot id: A0A0P0N2D1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1273541:Pyrde RS05820
gene id: 1273541:Pyrde_RS05820
uniprot id: A0A0P0N2Q5
names: Similarity
messages: Belongs to the UPF0235 family.

1273541:Pyrde RS08670
gene id: 1273541:Pyrde_RS08670
uniprot id: A0A0P0N4B9
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1273541:Pyrde RS04040
gene id: 1273541:Pyrde_RS04040
uniprot id: A0A0P0N2S1
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1273541:Pyrde RS05095
gene id: 1273541:Pyrde_RS05095
uniprot id: A0A0P0N2B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

1273541:Pyrde RS02555
gene id: 1273541:Pyrde_RS02555
uniprot id: A0A211YLT0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07275
gene id: 1273541:Pyrde_RS07275
uniprot id: A0A0P0N4U0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1273541:Pyrde RS04685
gene id: 1273541:Pyrde_RS04685
uniprot id: A0A0P0N2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1273541:Pyrde RS06510
gene id: 1273541:Pyrde_RS06510
uniprot id: A0A0P0N4G7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1273541:Pyrde RS06845
gene id: 1273541:Pyrde_RS06845
uniprot id: A0A0P0N4S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1273541:Pyrde RS05745
gene id: 1273541:Pyrde_RS05745
uniprot id: A0A0P0N443
names: Similarity
messages: Belongs to the glutamine synthetase family.

1273541:Pyrde RS00160
gene id: 1273541:Pyrde_RS00160
uniprot id: A0A211YQI6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09935
gene id: 1273541:Pyrde_RS09935
uniprot id: A0A0P0N6Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

1273541:Pyrde RS05615
gene id: 1273541:Pyrde_RS05615
uniprot id: A0A0P0N3Q1
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS05995
gene id: 1273541:Pyrde_RS05995
uniprot id: A0A0P0N4F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1273541:Pyrde RS06770
gene id: 1273541:Pyrde_RS06770
uniprot id: A0A0P0N3X0
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1273541:Pyrde RS00555
gene id: 1273541:Pyrde_RS00555
uniprot id: A0A0P0N1Q7
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1273541:Pyrde RS03180
gene id: 1273541:Pyrde_RS03180
uniprot id: A0A211YMJ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02240
gene id: 1273541:Pyrde_RS02240
uniprot id: A0A0P0N1E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1273541:Pyrde RS09465
gene id: 1273541:Pyrde_RS09465
uniprot id: A0A0P0N5I3
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1273541:Pyrde RS10070
gene id: 1273541:Pyrde_RS10070
uniprot id: A0A0P0N5W7
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1273541:Pyrde RS10940
gene id: 1273541:Pyrde_RS10940
uniprot id: A0A211YNX3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09450
gene id: 1273541:Pyrde_RS09450
uniprot id: A0A0P0N5U2
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1273541:Pyrde RS05100
gene id: 1273541:Pyrde_RS05100
uniprot id: A0A211YQT2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06280
gene id: 1273541:Pyrde_RS06280
uniprot id: A0A0P0N4C7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1273541:Pyrde RS08795
gene id: 1273541:Pyrde_RS08795
uniprot id: A0A211YPX1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08980
gene id: 1273541:Pyrde_RS08980
uniprot id: A0A0P0N5L4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1273541:Pyrde RS10245
gene id: 1273541:Pyrde_RS10245
uniprot id: A0A0P0N5Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

1273541:Pyrde RS06175
gene id: 1273541:Pyrde_RS06175
uniprot id: A0A0P0N3Y9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1273541:Pyrde RS09480
gene id: 1273541:Pyrde_RS09480
uniprot id: A0A0P0N4T6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

1273541:Pyrde RS09350
gene id: 1273541:Pyrde_RS09350
uniprot id: A0A0P0N568
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1273541:Pyrde RS01360
gene id: 1273541:Pyrde_RS01360
uniprot id: A0A0P0N0F8
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1273541:Pyrde RS05165
gene id: 1273541:Pyrde_RS05165
uniprot id: A0A211YQR8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02445
gene id: 1273541:Pyrde_RS02445
uniprot id: A0A0P0N246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1273541:Pyrde RS02800
gene id: 1273541:Pyrde_RS02800
uniprot id: A0A0P0N2T4
names: Subcellular Location Annotation
messages: Nucleus

1273541:Pyrde RS02390
gene id: 1273541:Pyrde_RS02390
uniprot id: A0A0P0N2N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1273541:Pyrde RS06475
gene id: 1273541:Pyrde_RS06475
uniprot id: A0A0P0N4M6
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1273541:Pyrde RS01990
gene id: 1273541:Pyrde_RS01990
uniprot id: A0A0P0N204
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1273541:Pyrde RS02230
gene id: 1273541:Pyrde_RS02230
uniprot id: A0A0P0N2X0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1273541:Pyrde RS08250
gene id: 1273541:Pyrde_RS08250
uniprot id: A0A211YQ97
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06505
gene id: 1273541:Pyrde_RS06505
uniprot id: A0A0P0N4M2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1273541:Pyrde RS06235
gene id: 1273541:Pyrde_RS06235
uniprot id: A0A0N7JD58
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1273541:Pyrde RS08580
gene id: 1273541:Pyrde_RS08580
uniprot id: A0A0P0N5I0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1273541:Pyrde RS05140
gene id: 1273541:Pyrde_RS05140
uniprot id: A0A0N7JD31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

1273541:Pyrde RS10115
gene id: 1273541:Pyrde_RS10115
uniprot id: A0A0P0N6J7
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

1273541:Pyrde RS06020
gene id: 1273541:Pyrde_RS06020
uniprot id: A0A0N7JD53
names: Similarity
messages: Belongs to the UPF0047 family.

1273541:Pyrde RS04780
gene id: 1273541:Pyrde_RS04780
uniprot id: A0A0N7JD22
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS07310
gene id: 1273541:Pyrde_RS07310
uniprot id: A0A211YNV7
names: Caution
names: Similarity
messages: Belongs to the AOR/FOR family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS00815
gene id: 1273541:Pyrde_RS00815
uniprot id: A0A0P0N1N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

1273541:Pyrde RS05815
gene id: 1273541:Pyrde_RS05815
uniprot id: A0A211YRQ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01915
gene id: 1273541:Pyrde_RS01915
uniprot id: A0A211YM55
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS00515
gene id: 1273541:Pyrde_RS00515
uniprot id: A0A0P0N213
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal MetE family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.

1273541:Pyrde RS07845
gene id: 1273541:Pyrde_RS07845
uniprot id: A0A0P0N541
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1273541:Pyrde RS01865
gene id: 1273541:Pyrde_RS01865
uniprot id: A0A0P0N2R1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS02145
gene id: 1273541:Pyrde_RS02145
uniprot id: A0A0P0N1S6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1273541:Pyrde RS02595
gene id: 1273541:Pyrde_RS02595
uniprot id: A0A0P0N1J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1273541:Pyrde RS10030
gene id: 1273541:Pyrde_RS10030
uniprot id: A0A211YPA9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09235
gene id: 1273541:Pyrde_RS09235
uniprot id: A0A0P0N548
names: Similarity
messages: Belongs to the carbamate kinase family.

1273541:Pyrde RS10060
gene id: 1273541:Pyrde_RS10060
uniprot id: A0A0P0N665
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1273541:Pyrde RS07235
gene id: 1273541:Pyrde_RS07235
uniprot id: A0A0P0N414
names: Similarity
messages: Belongs to the glutaredoxin family.

1273541:Pyrde RS03380
gene id: 1273541:Pyrde_RS03380
uniprot id: A0A211YMH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02520
gene id: 1273541:Pyrde_RS02520
uniprot id: A0A211YLS8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04775
gene id: 1273541:Pyrde_RS04775
uniprot id: A0A0P0N3K5
names: Similarity
messages: Belongs to the TrpF family.

1273541:Pyrde RS08430
gene id: 1273541:Pyrde_RS08430
uniprot id: A0A211YPS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05475
gene id: 1273541:Pyrde_RS05475
uniprot id: A0A0P0N3A2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1273541:Pyrde RS07210
gene id: 1273541:Pyrde_RS07210
uniprot id: A0A211YNT3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06405
gene id: 1273541:Pyrde_RS06405
uniprot id: A0A211YM07
names: Caution
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01805
gene id: 1273541:Pyrde_RS01805
uniprot id: A0A211YLR6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07415
gene id: 1273541:Pyrde_RS07415
uniprot id: A0A0P0N490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1273541:Pyrde RS08275
gene id: 1273541:Pyrde_RS08275
uniprot id: A0A0P0N5U9
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

1273541:Pyrde RS10125
gene id: 1273541:Pyrde_RS10125
uniprot id: A0A0N7JDF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1273541:Pyrde RS00770
gene id: 1273541:Pyrde_RS00770
uniprot id: A0A0P0N1P2
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS09945
gene id: 1273541:Pyrde_RS09945
uniprot id: A0A0P0N692
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1273541:Pyrde RS07265
gene id: 1273541:Pyrde_RS07265
uniprot id: A0A0P0N401
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1273541:Pyrde RS09340
gene id: 1273541:Pyrde_RS09340
uniprot id: A0A211YPY4
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06900
gene id: 1273541:Pyrde_RS06900
uniprot id: A0A0P0N3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

1273541:Pyrde RS01670
gene id: 1273541:Pyrde_RS01670
uniprot id: A0A211YNH0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1273541:Pyrde RS05960
gene id: 1273541:Pyrde_RS05960
uniprot id: A0A0P0N3A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1273541:Pyrde RS01775
gene id: 1273541:Pyrde_RS01775
uniprot id: A0A0P0N281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1273541:Pyrde RS02645
gene id: 1273541:Pyrde_RS02645
uniprot id: A0A0N7JCX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1273541:Pyrde RS05110
gene id: 1273541:Pyrde_RS05110
uniprot id: A0A0P0N4C8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1273541:Pyrde RS08150
gene id: 1273541:Pyrde_RS08150
uniprot id: A0A0P0N407
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1273541:Pyrde RS08930
gene id: 1273541:Pyrde_RS08930
uniprot id: A0A0P0N5B1
names: Similarity
messages: Belongs to the peptidase M20A family.

1273541:Pyrde RS02895
gene id: 1273541:Pyrde_RS02895
uniprot id: A0A0P0N1Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1273541:Pyrde RS01725
gene id: 1273541:Pyrde_RS01725
uniprot id: A0A0P0N1G4
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS01860
gene id: 1273541:Pyrde_RS01860
uniprot id: A0A0P0N0N3
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

1273541:Pyrde RS02080
gene id: 1273541:Pyrde_RS02080
uniprot id: A0A0P0N1N1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1273541:Pyrde RS02940
gene id: 1273541:Pyrde_RS02940
uniprot id: A0A0P0N211
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS07285
gene id: 1273541:Pyrde_RS07285
uniprot id: A0A211YP21
names: Caution
names: Similarity
messages: Belongs to the SAICAR synthetase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04200
gene id: 1273541:Pyrde_RS04200
uniprot id: A0A0P0N396
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

1273541:Pyrde RS09455
gene id: 1273541:Pyrde_RS09455
uniprot id: A0A0P0N5W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1273541:Pyrde RS05160
gene id: 1273541:Pyrde_RS05160
uniprot id: A0A0P0N4A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

1273541:Pyrde RS06675
gene id: 1273541:Pyrde_RS06675
uniprot id: A0A211YLK5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07005
gene id: 1273541:Pyrde_RS07005
uniprot id: A0A0P0N3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1273541:Pyrde RS02050
gene id: 1273541:Pyrde_RS02050
uniprot id: A0A0P0N2X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1273541:Pyrde RS09385
gene id: 1273541:Pyrde_RS09385
uniprot id: A0A0P0N5T7
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS05170
gene id: 1273541:Pyrde_RS05170
uniprot id: A0A211YQL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08815
gene id: 1273541:Pyrde_RS08815
uniprot id: A0A0P0N5I9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

1273541:Pyrde RS06195
gene id: 1273541:Pyrde_RS06195
uniprot id: A0A211YRK0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

1273541:Pyrde RS05805
gene id: 1273541:Pyrde_RS05805
uniprot id: A0A0P0N3F9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity.

1273541:Pyrde RS04225
gene id: 1273541:Pyrde_RS04225
uniprot id: A0A211YRA8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09490
gene id: 1273541:Pyrde_RS09490
uniprot id: A0A211YPN1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02355
gene id: 1273541:Pyrde_RS02355
uniprot id: A0A0N7JCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1273541:Pyrde RS05115
gene id: 1273541:Pyrde_RS05115
uniprot id: A0A0P0N3Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1273541:Pyrde RS08465
gene id: 1273541:Pyrde_RS08465
uniprot id: A0A0P0N5G2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

1273541:Pyrde RS01070
gene id: 1273541:Pyrde_RS01070
uniprot id: A0A0N7JCT1
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS08225
gene id: 1273541:Pyrde_RS08225
uniprot id: A0A0P0N5F4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1273541:Pyrde RS03280
gene id: 1273541:Pyrde_RS03280
uniprot id: A0A0N7JCY5
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS05190
gene id: 1273541:Pyrde_RS05190
uniprot id: A0A0P0N3R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1273541:Pyrde RS09140
gene id: 1273541:Pyrde_RS09140
uniprot id: A0A0P0N6A7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1273541:Pyrde RS02660
gene id: 1273541:Pyrde_RS02660
uniprot id: A0A0P0N2Q9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1273541:Pyrde RS02600
gene id: 1273541:Pyrde_RS02600
uniprot id: A0A0N7JCW9
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1273541:Pyrde RS08300
gene id: 1273541:Pyrde_RS08300
uniprot id: A0A0P0N5A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1273541:Pyrde RS02605
gene id: 1273541:Pyrde_RS02605
uniprot id: A0A0P0N2X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1273541:Pyrde RS10050
gene id: 1273541:Pyrde_RS10050
uniprot id: A0A0P0N6S3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1273541:Pyrde RS04735
gene id: 1273541:Pyrde_RS04735
uniprot id: A0A0P0N338
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

1273541:Pyrde RS10145
gene id: 1273541:Pyrde_RS10145
uniprot id: A0A211YQG1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08865
gene id: 1273541:Pyrde_RS08865
uniprot id: A0A211YQ75
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07215
gene id: 1273541:Pyrde_RS07215
uniprot id: A0A0N7JD82
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1273541:Pyrde RS04560
gene id: 1273541:Pyrde_RS04560
uniprot id: A0A0P0N2R6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1273541:Pyrde RS08380
gene id: 1273541:Pyrde_RS08380
uniprot id: A0A211YPT4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05930
gene id: 1273541:Pyrde_RS05930
uniprot id: A0A0N7JD51
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1273541:Pyrde RS08555
gene id: 1273541:Pyrde_RS08555
uniprot id: A0A0P0N499
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1273541:Pyrde RS04795
gene id: 1273541:Pyrde_RS04795
uniprot id: A0A0P0N2W6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1273541:Pyrde RS08285
gene id: 1273541:Pyrde_RS08285
uniprot id: A0A0P0N4H3
names: Similarity
messages: Belongs to the MCM family.

1273541:Pyrde RS07270
gene id: 1273541:Pyrde_RS07270
uniprot id: A0A0P0N574
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1273541:Pyrde RS02280
gene id: 1273541:Pyrde_RS02280
uniprot id: A0A0P0N368
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1273541:Pyrde RS03345
gene id: 1273541:Pyrde_RS03345
uniprot id: A0A0P0N2D7
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS03295
gene id: 1273541:Pyrde_RS03295
uniprot id: A0A0P0N259
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

1273541:Pyrde RS03175
gene id: 1273541:Pyrde_RS03175
uniprot id: A0A211YML1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01230
gene id: 1273541:Pyrde_RS01230
uniprot id: A0A0N7JCT5
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

1273541:Pyrde RS10150
gene id: 1273541:Pyrde_RS10150
uniprot id: A0A0P0N557
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1273541:Pyrde RS04355
gene id: 1273541:Pyrde_RS04355
uniprot id: A0A0P0N351
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1273541:Pyrde RS10235
gene id: 1273541:Pyrde_RS10235
uniprot id: A0A0P0N6C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1273541:Pyrde RS03670
gene id: 1273541:Pyrde_RS03670
uniprot id: A0A0P0N341
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1273541:Pyrde RS00200
gene id: 1273541:Pyrde_RS00200
uniprot id: A0A0P0MZW6
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1273541:Pyrde RS02680
gene id: 1273541:Pyrde_RS02680
uniprot id: A0A0P0N1W8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1273541:Pyrde RS02815
gene id: 1273541:Pyrde_RS02815
uniprot id: A0A0P0N2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Membrane

1273541:Pyrde RS08695
gene id: 1273541:Pyrde_RS08695
uniprot id: A0A0P0N5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1273541:Pyrde RS05300
gene id: 1273541:Pyrde_RS05300
uniprot id: A0A0P0N3D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1273541:Pyrde RS07930
gene id: 1273541:Pyrde_RS07930
uniprot id: A0A0N7JDA0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1273541:Pyrde RS08905
gene id: 1273541:Pyrde_RS08905
uniprot id: A0A0P0N671
names: Similarity
messages: Belongs to the Nth/MutY family.

1273541:Pyrde RS08640
gene id: 1273541:Pyrde_RS08640
uniprot id: A0A0P0N5G0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1273541:Pyrde RS09685
gene id: 1273541:Pyrde_RS09685
uniprot id: A0A0P0N685
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1273541:Pyrde RS01120
gene id: 1273541:Pyrde_RS01120
uniprot id: A0A211YN65
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06495
gene id: 1273541:Pyrde_RS06495
uniprot id: A0A211YLG4
names: Caution
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02740
gene id: 1273541:Pyrde_RS02740
uniprot id: A0A0P0N2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1273541:Pyrde RS00275
gene id: 1273541:Pyrde_RS00275
uniprot id: A0A211YQ57
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10040
gene id: 1273541:Pyrde_RS10040
uniprot id: A0A0P0N6S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1273541:Pyrde RS04800
gene id: 1273541:Pyrde_RS04800
uniprot id: A0A0P0N2W2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS07295
gene id: 1273541:Pyrde_RS07295
uniprot id: A0A0P0N513
names: Similarity
messages: Belongs to the P(II) protein family.

1273541:Pyrde RS09405
gene id: 1273541:Pyrde_RS09405
uniprot id: A0A0P0N5A8
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1273541:Pyrde RS07535
gene id: 1273541:Pyrde_RS07535
uniprot id: A0A0N7JD90
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS05125
gene id: 1273541:Pyrde_RS05125
uniprot id: A0A0P0N3T8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1273541:Pyrde RS05520
gene id: 1273541:Pyrde_RS05520
uniprot id: A0A211YSD9
names: Caution
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02755
gene id: 1273541:Pyrde_RS02755
uniprot id: A0A211YM13
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10045
gene id: 1273541:Pyrde_RS10045
uniprot id: A0A0N7JDF3
names: Function
messages: Probably involved in the biogenesis of the ribosome.

1273541:Pyrde RS03145
gene id: 1273541:Pyrde_RS03145
uniprot id: A0A0P0N2R5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1273541:Pyrde RS04860
gene id: 1273541:Pyrde_RS04860
uniprot id: A0A0N7JD24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1273541:Pyrde RS02285
gene id: 1273541:Pyrde_RS02285
uniprot id: A0A211YLT4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06545
gene id: 1273541:Pyrde_RS06545
uniprot id: A0A0P0N339
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS02335
gene id: 1273541:Pyrde_RS02335
uniprot id: A0A0P0N1R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

1273541:Pyrde RS08115
gene id: 1273541:Pyrde_RS08115
uniprot id: A0A0P0N5B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1273541:Pyrde RS07465
gene id: 1273541:Pyrde_RS07465
uniprot id: A0A0P0N456
names: Similarity
messages: Belongs to the complex I subunit 3 family.

1273541:Pyrde RS04925
gene id: 1273541:Pyrde_RS04925
uniprot id: A0A211YR22
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01450
gene id: 1273541:Pyrde_RS01450
uniprot id: A0A0P0N1J2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1273541:Pyrde RS07780
gene id: 1273541:Pyrde_RS07780
uniprot id: A0A0P0N511
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1273541:Pyrde RS08235
gene id: 1273541:Pyrde_RS08235
uniprot id: A0A0P0N593
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

1273541:Pyrde RS00565
gene id: 1273541:Pyrde_RS00565
uniprot id: A0A0P0N024
names: Similarity
messages: Belongs to the peptidase M24B family.

1273541:Pyrde RS00180
gene id: 1273541:Pyrde_RS00180
uniprot id: A0A0P0N1F4
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1273541:Pyrde RS01385
gene id: 1273541:Pyrde_RS01385
uniprot id: A0A211YN48
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS03440
gene id: 1273541:Pyrde_RS03440
uniprot id: A0A0P0N3B4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1273541:Pyrde RS07665
gene id: 1273541:Pyrde_RS07665
uniprot id: A0A0P0N570
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1273541:Pyrde RS06935
gene id: 1273541:Pyrde_RS06935
uniprot id: A0A211YN61
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07810
gene id: 1273541:Pyrde_RS07810
uniprot id: A0A0N7JD97
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS05155
gene id: 1273541:Pyrde_RS05155
uniprot id: A0A211YRX7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07985
gene id: 1273541:Pyrde_RS07985
uniprot id: A0A0P0N5V2
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS07805
gene id: 1273541:Pyrde_RS07805
uniprot id: A0A211YQE1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07585
gene id: 1273541:Pyrde_RS07585
uniprot id: A0A0P0N470
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1273541:Pyrde RS08255
gene id: 1273541:Pyrde_RS08255
uniprot id: A0A0P0N4K0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

1273541:Pyrde RS07890
gene id: 1273541:Pyrde_RS07890
uniprot id: A0A0N7JD99
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1273541:Pyrde RS06055
gene id: 1273541:Pyrde_RS06055
uniprot id: A0A211YRW3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06200
gene id: 1273541:Pyrde_RS06200
uniprot id: A0A0P0N2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1273541:Pyrde RS04600
gene id: 1273541:Pyrde_RS04600
uniprot id: A0A211YR02
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08170
gene id: 1273541:Pyrde_RS08170
uniprot id: A0A0P0N4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

1273541:Pyrde RS06960
gene id: 1273541:Pyrde_RS06960
uniprot id: A0A0N7JD76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1273541:Pyrde RS01585
gene id: 1273541:Pyrde_RS01585
uniprot id: A0A0P0N2R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1273541:Pyrde RS02275
gene id: 1273541:Pyrde_RS02275
uniprot id: A0A0P0N0V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm
messages: Homodimer.

1273541:Pyrde RS05090
gene id: 1273541:Pyrde_RS05090
uniprot id: A0A0P0N356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

1273541:Pyrde RS03015
gene id: 1273541:Pyrde_RS03015
uniprot id: A0A0P0N3H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm

1273541:Pyrde RS09280
gene id: 1273541:Pyrde_RS09280
uniprot id: A0A0P0N5H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS04845
gene id: 1273541:Pyrde_RS04845
uniprot id: A0A0P0N3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

1273541:Pyrde RS07065
gene id: 1273541:Pyrde_RS07065
uniprot id: A0A211YNV5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08525
gene id: 1273541:Pyrde_RS08525
uniprot id: A0A0P0N5E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1273541:Pyrde RS08425
gene id: 1273541:Pyrde_RS08425
uniprot id: A0A0P0N4Z2
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

1273541:Pyrde RS00605
gene id: 1273541:Pyrde_RS00605
uniprot id: A0A0P0N0X2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

1273541:Pyrde RS05185
gene id: 1273541:Pyrde_RS05185
uniprot id: A0A0N7JD32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1273541:Pyrde RS00725
gene id: 1273541:Pyrde_RS00725
uniprot id: A0A0P0N0Y9
names: Similarity
messages: Belongs to the UPF0273 family.

1273541:Pyrde RS04050
gene id: 1273541:Pyrde_RS04050
uniprot id: A0A0N7JD04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1273541:Pyrde RS03475
gene id: 1273541:Pyrde_RS03475
uniprot id: A0A0N7JCZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

1273541:Pyrde RS09275
gene id: 1273541:Pyrde_RS09275
uniprot id: A0A0P0N5R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).

1273541:Pyrde RS04140
gene id: 1273541:Pyrde_RS04140
uniprot id: A0A211YRV9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04215
gene id: 1273541:Pyrde_RS04215
uniprot id: A0A0N7JD08
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS02970
gene id: 1273541:Pyrde_RS02970
uniprot id: A0A0P0N2G8
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1273541:Pyrde RS04445
gene id: 1273541:Pyrde_RS04445
uniprot id: A0A0P0N2P5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1273541:Pyrde RS08800
gene id: 1273541:Pyrde_RS08800
uniprot id: A0A0P0N5Q4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1273541:Pyrde RS03395
gene id: 1273541:Pyrde_RS03395
uniprot id: A0A0N7JCY8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS04485
gene id: 1273541:Pyrde_RS04485
uniprot id: A0A0N7JD15
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

1273541:Pyrde RS00955
gene id: 1273541:Pyrde_RS00955
uniprot id: A0A0P0N127
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS08355
gene id: 1273541:Pyrde_RS08355
uniprot id: A0A0P0N5B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1273541:Pyrde RS01610
gene id: 1273541:Pyrde_RS01610
uniprot id: A0A0P0N1E1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1273541:Pyrde RS10175
gene id: 1273541:Pyrde_RS10175
uniprot id: A0A0P0N677
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1273541:Pyrde RS02925
gene id: 1273541:Pyrde_RS02925
uniprot id: A0A0P0N2N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

1273541:Pyrde RS09510
gene id: 1273541:Pyrde_RS09510
uniprot id: A0A0P0N5L9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

1273541:Pyrde RS00560
gene id: 1273541:Pyrde_RS00560
uniprot id: A0A211YMQ5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07895
gene id: 1273541:Pyrde_RS07895
uniprot id: A0A0P0N573
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1273541:Pyrde RS06580
gene id: 1273541:Pyrde_RS06580
uniprot id: A0A0P0N4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1273541:Pyrde RS07905
gene id: 1273541:Pyrde_RS07905
uniprot id: A0A0P0N4S0
names: Similarity
messages: Belongs to the GcvT family.

1273541:Pyrde RS06040
gene id: 1273541:Pyrde_RS06040
uniprot id: A0A0P0N473
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1273541:Pyrde RS02405
gene id: 1273541:Pyrde_RS02405
uniprot id: A0A0P0N0Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

1273541:Pyrde RS09300
gene id: 1273541:Pyrde_RS09300
uniprot id: A0A0P0N582
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

1273541:Pyrde RS02720
gene id: 1273541:Pyrde_RS02720
uniprot id: A0A0P0N2Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

1273541:Pyrde RS01810
gene id: 1273541:Pyrde_RS01810
uniprot id: A0A211YLJ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS00390
gene id: 1273541:Pyrde_RS00390
uniprot id: A0A211YPD2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04940
gene id: 1273541:Pyrde_RS04940
uniprot id: A0A0P0N2T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1273541:Pyrde RS05735
gene id: 1273541:Pyrde_RS05735
uniprot id: A0A0P0N4F0
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1273541:Pyrde RS02590
gene id: 1273541:Pyrde_RS02590
uniprot id: A0A0P0N334
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

1273541:Pyrde RS05200
gene id: 1273541:Pyrde_RS05200
uniprot id: A0A0P0N3B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

1273541:Pyrde RS07500
gene id: 1273541:Pyrde_RS07500
uniprot id: A0A0P0N5A3
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS08080
gene id: 1273541:Pyrde_RS08080
uniprot id: A0A0P0N5E9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1273541:Pyrde RS05060
gene id: 1273541:Pyrde_RS05060
uniprot id: A0A0P0N426
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1273541:Pyrde RS05080
gene id: 1273541:Pyrde_RS05080
uniprot id: A0A0P0N399
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

1273541:Pyrde RS10140
gene id: 1273541:Pyrde_RS10140
uniprot id: A0A0P0N6G3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1273541:Pyrde RS10950
gene id: 1273541:Pyrde_RS10950
uniprot id: A0A0N7JCR2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1273541:Pyrde RS02220
gene id: 1273541:Pyrde_RS02220
uniprot id: A0A0P0N0V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1273541:Pyrde RS07015
gene id: 1273541:Pyrde_RS07015
uniprot id: A0A0P0N4D3
names: Similarity
messages: Belongs to the HisA/HisF family.

1273541:Pyrde RS08175
gene id: 1273541:Pyrde_RS08175
uniprot id: A0A0P0N5M6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

1273541:Pyrde RS00610
gene id: 1273541:Pyrde_RS00610
uniprot id: A0A0P0N0W8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1273541:Pyrde RS00210
gene id: 1273541:Pyrde_RS00210
uniprot id: A0A0P0N262
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1273541:Pyrde RS02615
gene id: 1273541:Pyrde_RS02615
uniprot id: A0A0P0N2K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1273541:Pyrde RS04840
gene id: 1273541:Pyrde_RS04840
uniprot id: A0A0P0N3K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1273541:Pyrde RS06480
gene id: 1273541:Pyrde_RS06480
uniprot id: A0A0N7JD64
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1273541:Pyrde RS02820
gene id: 1273541:Pyrde_RS02820
uniprot id: A0A0P0N1Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

1273541:Pyrde RS07220
gene id: 1273541:Pyrde_RS07220
uniprot id: A0A211YNQ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10250
gene id: 1273541:Pyrde_RS10250
uniprot id: A0A0P0N6I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1273541:Pyrde RS06765
gene id: 1273541:Pyrde_RS06765
uniprot id: A0A0P0N3U0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

1273541:Pyrde RS01135
gene id: 1273541:Pyrde_RS01135
uniprot id: A0A211YNM4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07525
gene id: 1273541:Pyrde_RS07525
uniprot id: A0A0P0N4B1
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS10065
gene id: 1273541:Pyrde_RS10065
uniprot id: A0A0P0N652
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

1273541:Pyrde RS02990
gene id: 1273541:Pyrde_RS02990
uniprot id: A0A0N7JCX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers.

1273541:Pyrde RS10230
gene id: 1273541:Pyrde_RS10230
uniprot id: A0A211YQS6
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06540
gene id: 1273541:Pyrde_RS06540
uniprot id: A0A211YLJ5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02625
gene id: 1273541:Pyrde_RS02625
uniprot id: A0A0P0N2S2
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1273541:Pyrde RS02420
gene id: 1273541:Pyrde_RS02420
uniprot id: A0A211YMB4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10200
gene id: 1273541:Pyrde_RS10200
uniprot id: A0A0P0N5Q9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1273541:Pyrde RS00280
gene id: 1273541:Pyrde_RS00280
uniprot id: A0A211YNU9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS03825
gene id: 1273541:Pyrde_RS03825
uniprot id: A0A0P0N1P5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1273541:Pyrde RS08585
gene id: 1273541:Pyrde_RS08585
uniprot id: A0A0P0N5E7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS04730
gene id: 1273541:Pyrde_RS04730
uniprot id: A0A0P0N3K6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS05915
gene id: 1273541:Pyrde_RS05915
uniprot id: A0A0P0N3V5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

1273541:Pyrde RS09735
gene id: 1273541:Pyrde_RS09735
uniprot id: A0A0P0N5Q7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS06000
gene id: 1273541:Pyrde_RS06000
uniprot id: A0A0P0N3N8
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

1273541:Pyrde RS08350
gene id: 1273541:Pyrde_RS08350
uniprot id: A0A0P0N5E2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1273541:Pyrde RS06250
gene id: 1273541:Pyrde_RS06250
uniprot id: A0A211YS02
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01300
gene id: 1273541:Pyrde_RS01300
uniprot id: A0A0P0N189
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1273541:Pyrde RS09470
gene id: 1273541:Pyrde_RS09470
uniprot id: A0A0P0N635
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1273541:Pyrde RS02440
gene id: 1273541:Pyrde_RS02440
uniprot id: A0A0N7JCW5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1273541:Pyrde RS03140
gene id: 1273541:Pyrde_RS03140
uniprot id: A0A211YM40
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10085
gene id: 1273541:Pyrde_RS10085
uniprot id: A0A0N7JDF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1273541:Pyrde RS09420
gene id: 1273541:Pyrde_RS09420
uniprot id: A0A211YPB4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06680
gene id: 1273541:Pyrde_RS06680
uniprot id: A0A0P0N3N9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1273541:Pyrde RS01370
gene id: 1273541:Pyrde_RS01370
uniprot id: A0A0P0N2L9
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1273541:Pyrde RS09055
gene id: 1273541:Pyrde_RS09055
uniprot id: A0A0P0N4Y0
names: Similarity
messages: Belongs to the UPF0145 family.

1273541:Pyrde RS04195
gene id: 1273541:Pyrde_RS04195
uniprot id: A0A211YRE0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06215
gene id: 1273541:Pyrde_RS06215
uniprot id: A0A0P0N3F2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

1273541:Pyrde RS07740
gene id: 1273541:Pyrde_RS07740
uniprot id: A0A0P0N4L7
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS02695
gene id: 1273541:Pyrde_RS02695
uniprot id: A0A0P0N1W2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1273541:Pyrde RS07755
gene id: 1273541:Pyrde_RS07755
uniprot id: A0A0P0N3S2
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS06755
gene id: 1273541:Pyrde_RS06755
uniprot id: A0A0P0N3V3
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1273541:Pyrde RS08590
gene id: 1273541:Pyrde_RS08590
uniprot id: A0A0P0N547
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

1273541:Pyrde RS08280
gene id: 1273541:Pyrde_RS08280
uniprot id: A0A211YQM9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05455
gene id: 1273541:Pyrde_RS05455
uniprot id: A0A0N7JD39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS01910
gene id: 1273541:Pyrde_RS01910
uniprot id: A0A211YLR4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10105
gene id: 1273541:Pyrde_RS10105
uniprot id: A0A0P0N600
names: Similarity
messages: Belongs to the DMRL synthase family.

1273541:Pyrde RS08200
gene id: 1273541:Pyrde_RS08200
uniprot id: A0A0P0N4M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1273541:Pyrde RS05375
gene id: 1273541:Pyrde_RS05375
uniprot id: A0A0P0N2I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1273541:Pyrde RS09885
gene id: 1273541:Pyrde_RS09885
uniprot id: A0A0P0N5B0
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1273541:Pyrde RS02270
gene id: 1273541:Pyrde_RS02270
uniprot id: A0A0P0N1M8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1273541:Pyrde RS10025
gene id: 1273541:Pyrde_RS10025
uniprot id: A0A0P0N5U8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

1273541:Pyrde RS07185
gene id: 1273541:Pyrde_RS07185
uniprot id: A0A0P0N5B8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1273541:Pyrde RS04060
gene id: 1273541:Pyrde_RS04060
uniprot id: A0A0P0N1U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1273541:Pyrde RS02015
gene id: 1273541:Pyrde_RS02015
uniprot id: A0A0N7JCV5
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1273541:Pyrde RS08220
gene id: 1273541:Pyrde_RS08220
uniprot id: A0A0P0N5T6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1273541:Pyrde RS05285
gene id: 1273541:Pyrde_RS05285
uniprot id: A0A0P0N464
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

1273541:Pyrde RS01125
gene id: 1273541:Pyrde_RS01125
uniprot id: A0A0P0N1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1273541:Pyrde RS04175
gene id: 1273541:Pyrde_RS04175
uniprot id: A0A0N7JD07
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS01095
gene id: 1273541:Pyrde_RS01095
uniprot id: A0A211YN08
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07545
gene id: 1273541:Pyrde_RS07545
uniprot id: A0A0P0N5L5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1273541:Pyrde RS01760
gene id: 1273541:Pyrde_RS01760
uniprot id: A0A0N7JCU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

1273541:Pyrde RS03250
gene id: 1273541:Pyrde_RS03250
uniprot id: A0A211YM44
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06780
gene id: 1273541:Pyrde_RS06780
uniprot id: A0A0P0N528
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1273541:Pyrde RS08215
gene id: 1273541:Pyrde_RS08215
uniprot id: A0A0P0N5Z0
names: Similarity
messages: Belongs to the UPF0173 family.

1273541:Pyrde RS09740
gene id: 1273541:Pyrde_RS09740
uniprot id: A0A0P0N5B2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS10255
gene id: 1273541:Pyrde_RS10255
uniprot id: A0A0P0N5L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1273541:Pyrde RS02170
gene id: 1273541:Pyrde_RS02170
uniprot id: A0A0P0N2Z5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1273541:Pyrde RS01245
gene id: 1273541:Pyrde_RS01245
uniprot id: A0A0P0N232
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1273541:Pyrde RS02020
gene id: 1273541:Pyrde_RS02020
uniprot id: A0A0P0N2B0
names: Similarity
messages: Belongs to the HypE family.

1273541:Pyrde RS05725
gene id: 1273541:Pyrde_RS05725
uniprot id: A0A0N7JD46
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS01365
gene id: 1273541:Pyrde_RS01365
uniprot id: A0A0P0N2R4
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1273541:Pyrde RS04495
gene id: 1273541:Pyrde_RS04495
uniprot id: A0A0P0N2Z4
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS05040
gene id: 1273541:Pyrde_RS05040
uniprot id: A0A0P0N484
names: Similarity
messages: Belongs to the P(II) protein family.

1273541:Pyrde RS01895
gene id: 1273541:Pyrde_RS01895
uniprot id: A0A0P0N290
names: Similarity
messages: Belongs to the aspartokinase family.

1273541:Pyrde RS04805
gene id: 1273541:Pyrde_RS04805
uniprot id: A0A0P0N2X1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS09265
gene id: 1273541:Pyrde_RS09265
uniprot id: A0A0P0N5Y3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1273541:Pyrde RS06945
gene id: 1273541:Pyrde_RS06945
uniprot id: A0A0P0N397
names: Similarity
messages: Belongs to the peptidase C15 family.

1273541:Pyrde RS08535
gene id: 1273541:Pyrde_RS08535
uniprot id: A0A211YQ46
names: Caution
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS03165
gene id: 1273541:Pyrde_RS03165
uniprot id: A0A0P0N2G0
names: Similarity
messages: Belongs to the peptidase S8 family.

1273541:Pyrde RS04305
gene id: 1273541:Pyrde_RS04305
uniprot id: A0A211YR07
names: Caution
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02375
gene id: 1273541:Pyrde_RS02375
uniprot id: A0A0P0N2I2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

1273541:Pyrde RS08120
gene id: 1273541:Pyrde_RS08120
uniprot id: A0A0P0N575
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1273541:Pyrde RS10225
gene id: 1273541:Pyrde_RS10225
uniprot id: A0A211YQ62
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06630
gene id: 1273541:Pyrde_RS06630
uniprot id: A0A211YLJ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01100
gene id: 1273541:Pyrde_RS01100
uniprot id: A0A211YNF1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09025
gene id: 1273541:Pyrde_RS09025
uniprot id: A0A0P0N5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1273541:Pyrde RS09525
gene id: 1273541:Pyrde_RS09525
uniprot id: A0A0P0N5D5
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS00855
gene id: 1273541:Pyrde_RS00855
uniprot id: A0A211YMM3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS03365
gene id: 1273541:Pyrde_RS03365
uniprot id: A0A0P0N3N7
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1273541:Pyrde RS00800
gene id: 1273541:Pyrde_RS00800
uniprot id: A0A0P0N2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1273541:Pyrde RS03030
gene id: 1273541:Pyrde_RS03030
uniprot id: A0A211YM25
names: Caution
names: Similarity
messages: Belongs to the SUI1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05325
gene id: 1273541:Pyrde_RS05325
uniprot id: A0A0P0N4H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

1273541:Pyrde RS07170
gene id: 1273541:Pyrde_RS07170
uniprot id: A0A211YNJ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09045
gene id: 1273541:Pyrde_RS09045
uniprot id: A0A0N7JDC8
names: Similarity
messages: Belongs to the peptidase C56 family.

1273541:Pyrde RS08950
gene id: 1273541:Pyrde_RS08950
uniprot id: A0A0P0N4J4
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS08570
gene id: 1273541:Pyrde_RS08570
uniprot id: A0A211YQ89
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02870
gene id: 1273541:Pyrde_RS02870
uniprot id: A0A0P0N2R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1273541:Pyrde RS08920
gene id: 1273541:Pyrde_RS08920
uniprot id: A0A0P0N5K9
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS02885
gene id: 1273541:Pyrde_RS02885
uniprot id: A0A0P0N257
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1273541:Pyrde RS09220
gene id: 1273541:Pyrde_RS09220
uniprot id: A0A0P0N5S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1273541:Pyrde RS08755
gene id: 1273541:Pyrde_RS08755
uniprot id: A0A0P0N5I2
names: Similarity
messages: Belongs to the UbiD family.

1273541:Pyrde RS04870
gene id: 1273541:Pyrde_RS04870
uniprot id: A0A0P0N279
names: Similarity
messages: Belongs to the PstS family.

1273541:Pyrde RS00550
gene id: 1273541:Pyrde_RS00550
uniprot id: A0A0P0N138
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1273541:Pyrde RS04075
gene id: 1273541:Pyrde_RS04075
uniprot id: A0A211YR48
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08230
gene id: 1273541:Pyrde_RS08230
uniprot id: A0A0P0N5C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1273541:Pyrde RS06030
gene id: 1273541:Pyrde_RS06030
uniprot id: A0A0P0N4D6
names: Similarity
messages: Belongs to the BtpA family.

1273541:Pyrde RS07100
gene id: 1273541:Pyrde_RS07100
uniprot id: A0A0P0N3Z0
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS03270
gene id: 1273541:Pyrde_RS03270
uniprot id: A0A0P0N2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1273541:Pyrde RS07955
gene id: 1273541:Pyrde_RS07955
uniprot id: A0A0P0N558
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1273541:Pyrde RS06190
gene id: 1273541:Pyrde_RS06190
uniprot id: A0A0P0N3M7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1273541:Pyrde RS00485
gene id: 1273541:Pyrde_RS00485
uniprot id: A0A211YMG2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07230
gene id: 1273541:Pyrde_RS07230
uniprot id: A0A0P0N410
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1273541:Pyrde RS02235
gene id: 1273541:Pyrde_RS02235
uniprot id: A0A0P0N244
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

1273541:Pyrde RS02460
gene id: 1273541:Pyrde_RS02460
uniprot id: A0A0P0N1S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1273541:Pyrde RS02350
gene id: 1273541:Pyrde_RS02350
uniprot id: A0A0P0N2Y9
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS02255
gene id: 1273541:Pyrde_RS02255
uniprot id: A0A0P0N1U6
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1273541:Pyrde RS02200
gene id: 1273541:Pyrde_RS02200
uniprot id: A0A0P0N206
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1273541:Pyrde RS02225
gene id: 1273541:Pyrde_RS02225
uniprot id: A0A0N7JCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1273541:Pyrde RS08085
gene id: 1273541:Pyrde_RS08085
uniprot id: A0A0N7JDA4
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1273541:Pyrde RS00295
gene id: 1273541:Pyrde_RS00295
uniprot id: A0A0P0N1I8
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1273541:Pyrde RS03465
gene id: 1273541:Pyrde_RS03465
uniprot id: A0A0P0N299
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

1273541:Pyrde RS07920
gene id: 1273541:Pyrde_RS07920
uniprot id: A0A0P0N4H8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1273541:Pyrde RS03860
gene id: 1273541:Pyrde_RS03860
uniprot id: A0A0P0N2S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1273541:Pyrde RS08345
gene id: 1273541:Pyrde_RS08345
uniprot id: A0A211YQ03
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05105
gene id: 1273541:Pyrde_RS05105
uniprot id: A0A0P0N4G4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1273541:Pyrde RS08435
gene id: 1273541:Pyrde_RS08435
uniprot id: A0A0P0N4R4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS02395
gene id: 1273541:Pyrde_RS02395
uniprot id: A0A211YLQ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09125
gene id: 1273541:Pyrde_RS09125
uniprot id: A0A211YQ78
names: Caution
names: Similarity
messages: Belongs to the CutA family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02975
gene id: 1273541:Pyrde_RS02975
uniprot id: A0A211YM14
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04340
gene id: 1273541:Pyrde_RS04340
uniprot id: A0A0P0N2M9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1273541:Pyrde RS06070
gene id: 1273541:Pyrde_RS06070
uniprot id: A0A211YRJ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS00830
gene id: 1273541:Pyrde_RS00830
uniprot id: A0A0P0N1D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1273541:Pyrde RS07280
gene id: 1273541:Pyrde_RS07280
uniprot id: A0A0P0N4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1273541:Pyrde RS08420
gene id: 1273541:Pyrde_RS08420
uniprot id: A0A0P0N5D1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1273541:Pyrde RS02205
gene id: 1273541:Pyrde_RS02205
uniprot id: A0A0P0N1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1273541:Pyrde RS02635
gene id: 1273541:Pyrde_RS02635
uniprot id: A0A0P0N1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1273541:Pyrde RS02450
gene id: 1273541:Pyrde_RS02450
uniprot id: A0A0P0N1T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS05180
gene id: 1273541:Pyrde_RS05180
uniprot id: A0A0P0N447
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1273541:Pyrde RS02370
gene id: 1273541:Pyrde_RS02370
uniprot id: A0A0P0N2T3
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

1273541:Pyrde RS08325
gene id: 1273541:Pyrde_RS08325
uniprot id: A0A0P0N468
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1273541:Pyrde RS07935
gene id: 1273541:Pyrde_RS07935
uniprot id: A0A0P0N5M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

1273541:Pyrde RS02380
gene id: 1273541:Pyrde_RS02380
uniprot id: A0A0P0N2G6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1273541:Pyrde RS04515
gene id: 1273541:Pyrde_RS04515
uniprot id: A0A211YQZ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04220
gene id: 1273541:Pyrde_RS04220
uniprot id: A0A0P0N2L5
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS00665
gene id: 1273541:Pyrde_RS00665
uniprot id: A0A0N7JCS1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1273541:Pyrde RS08515
gene id: 1273541:Pyrde_RS08515
uniprot id: A0A0P0N4L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

1273541:Pyrde RS05245
gene id: 1273541:Pyrde_RS05245
uniprot id: A0A0P0N3V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1273541:Pyrde RS09900
gene id: 1273541:Pyrde_RS09900
uniprot id: A0A0P0N619
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1273541:Pyrde RS04290
gene id: 1273541:Pyrde_RS04290
uniprot id: A0A0P0N1Y3
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

1273541:Pyrde RS02670
gene id: 1273541:Pyrde_RS02670
uniprot id: A0A0P0N2M4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1273541:Pyrde RS02365
gene id: 1273541:Pyrde_RS02365
uniprot id: A0A0P0N1G5
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

1273541:Pyrde RS08835
gene id: 1273541:Pyrde_RS08835
uniprot id: A0A211YPL0
names: Caution
names: Similarity
messages: Belongs to the AOR/FOR family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08935
gene id: 1273541:Pyrde_RS08935
uniprot id: A0A211YQE3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08245
gene id: 1273541:Pyrde_RS08245
uniprot id: A0A211YQI7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10240
gene id: 1273541:Pyrde_RS10240
uniprot id: A0A0N7JDF8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1273541:Pyrde RS08315
gene id: 1273541:Pyrde_RS08315
uniprot id: A0A0P0N5I6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1273541:Pyrde RS08090
gene id: 1273541:Pyrde_RS08090
uniprot id: A0A211YPZ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS02690
gene id: 1273541:Pyrde_RS02690
uniprot id: A0A0P0N1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1273541:Pyrde RS02575
gene id: 1273541:Pyrde_RS02575
uniprot id: A0A0P0N1U5
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

1273541:Pyrde RS00930
gene id: 1273541:Pyrde_RS00930
uniprot id: A0A211YMN1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05275
gene id: 1273541:Pyrde_RS05275
uniprot id: A0A211YQL8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS00680
gene id: 1273541:Pyrde_RS00680
uniprot id: A0A0P0N044
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

1273541:Pyrde RS09705
gene id: 1273541:Pyrde_RS09705
uniprot id: A0A0P0N6K7
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1273541:Pyrde RS04380
gene id: 1273541:Pyrde_RS04380
uniprot id: A0A211YQZ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08995
gene id: 1273541:Pyrde_RS08995
uniprot id: A0A0P0N5V5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1273541:Pyrde RS08470
gene id: 1273541:Pyrde_RS08470
uniprot id: A0A0P0N5C7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1273541:Pyrde RS02920
gene id: 1273541:Pyrde_RS02920
uniprot id: A0A0P0N2W4
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

1273541:Pyrde RS00490
gene id: 1273541:Pyrde_RS00490
uniprot id: A0A211YMT9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05965
gene id: 1273541:Pyrde_RS05965
uniprot id: A0A0P0N4J1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1273541:Pyrde RS05135
gene id: 1273541:Pyrde_RS05135
uniprot id: A0A211YR28
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08360
gene id: 1273541:Pyrde_RS08360
uniprot id: A0A0P0N515
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1273541:Pyrde RS05705
gene id: 1273541:Pyrde_RS05705
uniprot id: A0A0P0N3A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1273541:Pyrde RS05020
gene id: 1273541:Pyrde_RS05020
uniprot id: A0A0P0N308
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

1273541:Pyrde RS05690
gene id: 1273541:Pyrde_RS05690
uniprot id: A0A0N7JD45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1273541:Pyrde RS00520
gene id: 1273541:Pyrde_RS00520
uniprot id: A0A0P0N1A1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

1273541:Pyrde RS08040
gene id: 1273541:Pyrde_RS08040
uniprot id: A0A0P0N5P9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1273541:Pyrde RS06430
gene id: 1273541:Pyrde_RS06430
uniprot id: A0A0P0N4X2
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS09770
gene id: 1273541:Pyrde_RS09770
uniprot id: A0A0N7JDE6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1273541:Pyrde RS00635
gene id: 1273541:Pyrde_RS00635
uniprot id: A0A211YMP2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10185
gene id: 1273541:Pyrde_RS10185
uniprot id: A0A0P0N5Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

1273541:Pyrde RS06775
gene id: 1273541:Pyrde_RS06775
uniprot id: A0A0P0N377
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1273541:Pyrde RS04100
gene id: 1273541:Pyrde_RS04100
uniprot id: A0A0P0N2W7
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1273541:Pyrde RS02385
gene id: 1273541:Pyrde_RS02385
uniprot id: A0A0P0N1W3
names: Similarity
messages: Belongs to the PDCD5 family.

1273541:Pyrde RS08295
gene id: 1273541:Pyrde_RS08295
uniprot id: A0A0P0N5P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1273541:Pyrde RS04565
gene id: 1273541:Pyrde_RS04565
uniprot id: A0A211YRZ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS06440
gene id: 1273541:Pyrde_RS06440
uniprot id: A0A0N7JD63
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1273541:Pyrde RS04520
gene id: 1273541:Pyrde_RS04520
uniprot id: A0A211YR61
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10735
gene id: 1273541:Pyrde_RS10735
uniprot id: A0A0P0N5A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1273541:Pyrde RS03245
gene id: 1273541:Pyrde_RS03245
uniprot id: A0A211YMD9
names: Caution
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05225
gene id: 1273541:Pyrde_RS05225
uniprot id: A0A211YS41
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS03840
gene id: 1273541:Pyrde_RS03840
uniprot id: A0A211YRY9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09485
gene id: 1273541:Pyrde_RS09485
uniprot id: A0A0P0N6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1273541:Pyrde RS07245
gene id: 1273541:Pyrde_RS07245
uniprot id: A0A0P0N3H4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1273541:Pyrde RS02550
gene id: 1273541:Pyrde_RS02550
uniprot id: A0A0P0N2J0
names: Similarity
messages: Belongs to the UPF0147 family.

1273541:Pyrde RS01350
gene id: 1273541:Pyrde_RS01350
uniprot id: A0A211YN43
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS08155
gene id: 1273541:Pyrde_RS08155
uniprot id: A0A0P0N5S7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

1273541:Pyrde RS00945
gene id: 1273541:Pyrde_RS00945
uniprot id: A0A0P0N1F2
names: Similarity
messages: Belongs to the peptidase S9C family.

1273541:Pyrde RS10205
gene id: 1273541:Pyrde_RS10205
uniprot id: A0A0N7JDF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS02360
gene id: 1273541:Pyrde_RS02360
uniprot id: A0A0P0N265
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1273541:Pyrde RS04095
gene id: 1273541:Pyrde_RS04095
uniprot id: A0A0N7JD05
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1273541:Pyrde RS05130
gene id: 1273541:Pyrde_RS05130
uniprot id: A0A0P0N3F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1273541:Pyrde RS04190
gene id: 1273541:Pyrde_RS04190
uniprot id: A0A0P0N3Y3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1273541:Pyrde RS02330
gene id: 1273541:Pyrde_RS02330
uniprot id: A0A0P0N1R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1273541:Pyrde RS07160
gene id: 1273541:Pyrde_RS07160
uniprot id: A0A211YPB9
names: Caution
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05765
gene id: 1273541:Pyrde_RS05765
uniprot id: A0A0N7JD47
names: Similarity
messages: Belongs to the HerA family.

1273541:Pyrde RS10935
gene id: 1273541:Pyrde_RS10935
uniprot id: A0A211YNM5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05065
gene id: 1273541:Pyrde_RS05065
uniprot id: A0A0P0N3P5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

1273541:Pyrde RS07785
gene id: 1273541:Pyrde_RS07785
uniprot id: A0A0P0N4R5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1273541:Pyrde RS01815
gene id: 1273541:Pyrde_RS01815
uniprot id: A0A0P0N2U3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1273541:Pyrde RS01565
gene id: 1273541:Pyrde_RS01565
uniprot id: A0A0N7JCU4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1273541:Pyrde RS05755
gene id: 1273541:Pyrde_RS05755
uniprot id: A0A0P0N4B4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

1273541:Pyrde RS09845
gene id: 1273541:Pyrde_RS09845
uniprot id: A0A0P0N5S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1273541:Pyrde RS06840
gene id: 1273541:Pyrde_RS06840
uniprot id: A0A0P0N563
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1273541:Pyrde RS02655
gene id: 1273541:Pyrde_RS02655
uniprot id: A0A0P0N375
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1273541:Pyrde RS09780
gene id: 1273541:Pyrde_RS09780
uniprot id: A0A0P0N6D5
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS06585
gene id: 1273541:Pyrde_RS06585
uniprot id: A0A0P0N3Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1273541:Pyrde RS04985
gene id: 1273541:Pyrde_RS04985
uniprot id: A0A0P0N4F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1273541:Pyrde RS06160
gene id: 1273541:Pyrde_RS06160
uniprot id: A0A0P0N5M6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

1273541:Pyrde RS05715
gene id: 1273541:Pyrde_RS05715
uniprot id: A0A0P0N2N6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Membrane

1273541:Pyrde RS01920
gene id: 1273541:Pyrde_RS01920
uniprot id: A0A0P0N0P8
names: Similarity
messages: Belongs to the hemerythrin family.

1273541:Pyrde RS09285
gene id: 1273541:Pyrde_RS09285
uniprot id: A0A211YPE8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09355
gene id: 1273541:Pyrde_RS09355
uniprot id: A0A0P0N4P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1273541:Pyrde RS06965
gene id: 1273541:Pyrde_RS06965
uniprot id: A0A0P0N4U6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1273541:Pyrde RS04785
gene id: 1273541:Pyrde_RS04785
uniprot id: A0A0P0N3M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1273541:Pyrde RS09130
gene id: 1273541:Pyrde_RS09130
uniprot id: A0A0N7JDD0
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS05390
gene id: 1273541:Pyrde_RS05390
uniprot id: A0A211YS38
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS03285
gene id: 1273541:Pyrde_RS03285
uniprot id: A0A0P0N2H8
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS00660
gene id: 1273541:Pyrde_RS00660
uniprot id: A0A0P0N153
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1273541:Pyrde RS03830
gene id: 1273541:Pyrde_RS03830
uniprot id: A0A211YRK1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01545
gene id: 1273541:Pyrde_RS01545
uniprot id: A0A0P0N235
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1273541:Pyrde RS07360
gene id: 1273541:Pyrde_RS07360
uniprot id: A0A0P0N476
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS05760
gene id: 1273541:Pyrde_RS05760
uniprot id: A0A0P0N3I5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

1273541:Pyrde RS04000
gene id: 1273541:Pyrde_RS04000
uniprot id: A0A0P0N1U0
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1273541:Pyrde RS09035
gene id: 1273541:Pyrde_RS09035
uniprot id: A0A0P0N5M9
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS06550
gene id: 1273541:Pyrde_RS06550
uniprot id: A0A0P0N4Y8
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS02950
gene id: 1273541:Pyrde_RS02950
uniprot id: A0A211YMA5
names: Caution
names: Similarity
messages: Belongs to the Ahb/Nir family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05425
gene id: 1273541:Pyrde_RS05425
uniprot id: A0A0P0N3C4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1273541:Pyrde RS04035
gene id: 1273541:Pyrde_RS04035
uniprot id: A0A0P0N392
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1273541:Pyrde RS00790
gene id: 1273541:Pyrde_RS00790
uniprot id: A0A0P0N0W0
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS09905
gene id: 1273541:Pyrde_RS09905
uniprot id: A0A211YQT7
names: Caution
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS05120
gene id: 1273541:Pyrde_RS05120
uniprot id: A0A0P0N3S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1273541:Pyrde RS07610
gene id: 1273541:Pyrde_RS07610
uniprot id: A0A0P0N455
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

1273541:Pyrde RS02025
gene id: 1273541:Pyrde_RS02025
uniprot id: A0A0P0N1R3
names: Similarity
messages: Belongs to the HupF/HypC family.

1273541:Pyrde RS03955
gene id: 1273541:Pyrde_RS03955
uniprot id: A0A211YRI0
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04790
gene id: 1273541:Pyrde_RS04790
uniprot id: A0A0P0N380
names: Function
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1273541:Pyrde RS01420
gene id: 1273541:Pyrde_RS01420
uniprot id: A0A0P0N2J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1273541:Pyrde RS09675
gene id: 1273541:Pyrde_RS09675
uniprot id: A0A0P0N606
names: Similarity
messages: Belongs to the class-I fumarase family.

1273541:Pyrde RS02345
gene id: 1273541:Pyrde_RS02345
uniprot id: A0A0P0N0X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1273541:Pyrde RS07700
gene id: 1273541:Pyrde_RS07700
uniprot id: A0A211YNU2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS03370
gene id: 1273541:Pyrde_RS03370
uniprot id: A0A0P0N3J8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1273541:Pyrde RS05825
gene id: 1273541:Pyrde_RS05825
uniprot id: A0A0P0N4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1273541:Pyrde RS05240
gene id: 1273541:Pyrde_RS05240
uniprot id: A0A211YRS9
names: Caution
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04615
gene id: 1273541:Pyrde_RS04615
uniprot id: A0A211YRL2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04995
gene id: 1273541:Pyrde_RS04995
uniprot id: A0A0P0N3W4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1273541:Pyrde RS09295
gene id: 1273541:Pyrde_RS09295
uniprot id: A0A0N7JDD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

1273541:Pyrde RS08485
gene id: 1273541:Pyrde_RS08485
uniprot id: A0A0P0N4L9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1273541:Pyrde RS01680
gene id: 1273541:Pyrde_RS01680
uniprot id: A0A211YN38
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS07550
gene id: 1273541:Pyrde_RS07550
uniprot id: A0A0P0N5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1273541:Pyrde RS02030
gene id: 1273541:Pyrde_RS02030
uniprot id: A0A0P0N2F8
names: Similarity
messages: Belongs to the HypD family.

1273541:Pyrde RS07205
gene id: 1273541:Pyrde_RS07205
uniprot id: A0A211YNJ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04260
gene id: 1273541:Pyrde_RS04260
uniprot id: A0A0P0N3P7
names: Subcellular Location Annotation
messages: Membrane

1273541:Pyrde RS10055
gene id: 1273541:Pyrde_RS10055
uniprot id: A0A0P0N6B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1273541:Pyrde RS03130
gene id: 1273541:Pyrde_RS03130
uniprot id: A0A211YM78
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS10260
gene id: 1273541:Pyrde_RS10260
uniprot id: A0A211YP59
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS01055
gene id: 1273541:Pyrde_RS01055
uniprot id: A0A211YN21
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS09760
gene id: 1273541:Pyrde_RS09760
uniprot id: A0A0P0N6P1
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1273541:Pyrde RS02475
gene id: 1273541:Pyrde_RS02475
uniprot id: A0A0P0N284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1273541:Pyrde RS05910
gene id: 1273541:Pyrde_RS05910
uniprot id: A0A0P0N460
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1273541:Pyrde RS08330
gene id: 1273541:Pyrde_RS08330
uniprot id: A0A0N7JDB0
names: Function
messages: Part of a potassium transport system.

1273541:Pyrde RS09730
gene id: 1273541:Pyrde_RS09730
uniprot id: A0A0N7JDE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1273541:Pyrde RS05610
gene id: 1273541:Pyrde_RS05610
uniprot id: A0A0N7JD43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

1273541:Pyrde RS00110
gene id: 1273541:Pyrde_RS00110
uniprot id: A0A0P0N1E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1273541:Pyrde RS03115
gene id: 1273541:Pyrde_RS03115
uniprot id: A0A0P0N2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1273541:Pyrde RS07470
gene id: 1273541:Pyrde_RS07470
uniprot id: A0A0P0N496
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1273541:Pyrde RS04185
gene id: 1273541:Pyrde_RS04185
uniprot id: A0A0P0N417
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1273541:Pyrde RS05150
gene id: 1273541:Pyrde_RS05150
uniprot id: A0A0P0N331
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1273541:Pyrde RS00325
gene id: 1273541:Pyrde_RS00325
uniprot id: A0A0P0MZY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

1273541:Pyrde RS10170
gene id: 1273541:Pyrde_RS10170
uniprot id: A0A0P0N6D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

1273541:Pyrde RS08400
gene id: 1273541:Pyrde_RS08400
uniprot id: A0A0P0N4J3
names: Similarity
messages: Belongs to the glutaredoxin family.

1273541:Pyrde RS04465
gene id: 1273541:Pyrde_RS04465
uniprot id: A0A211YR20
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1273541:Pyrde RS04065
gene id: 1273541:Pyrde_RS04065
uniprot id: A0A0P0N3Z5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1273541:Pyrde RS02495
gene id: 1273541:Pyrde_RS02495
uniprot id: A0A0P0N2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane