1267766:WYH RS08045
gene id: 1267766:WYH_RS08045
uniprot id: A0A0F7KSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1267766:WYH RS05235
gene id: 1267766:WYH_RS05235
uniprot id: A0A0F7KS55
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS09010
gene id: 1267766:WYH_RS09010
uniprot id: A0A0F7KUB8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1267766:WYH RS04960
gene id: 1267766:WYH_RS04960
uniprot id: A0A0F7KR36
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS03330
gene id: 1267766:WYH_RS03330
uniprot id: A0A0F7KSI9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1267766:WYH RS17305
gene id: 1267766:WYH_RS17305
uniprot id: A0A0F7KW97
names: Subcellular Location Annotation
messages: Cytoplasm

1267766:WYH RS02125
gene id: 1267766:WYH_RS02125
uniprot id: A0A0F7KQP4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1267766:WYH RS09355
gene id: 1267766:WYH_RS09355
uniprot id: A0A0F7KVZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1267766:WYH RS13285
gene id: 1267766:WYH_RS13285
uniprot id: A0A0F7KY42
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1267766:WYH RS01875
gene id: 1267766:WYH_RS01875
uniprot id: A0A0F7KPF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1267766:WYH RS09605
gene id: 1267766:WYH_RS09605
uniprot id: A0A0F7KW28
names: Similarity
messages: Belongs to the pyruvate kinase family.

1267766:WYH RS02305
gene id: 1267766:WYH_RS02305
uniprot id: A0A0F7KQS4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1267766:WYH RS09695
gene id: 1267766:WYH_RS09695
uniprot id: A0A0F7KRB6
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1267766:WYH RS02755
gene id: 1267766:WYH_RS02755
uniprot id: A0A0F7KM38
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1267766:WYH RS09125
gene id: 1267766:WYH_RS09125
uniprot id: A0A0F7KVV8
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS07590
gene id: 1267766:WYH_RS07590
uniprot id: A0A0F7KSM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS04980
gene id: 1267766:WYH_RS04980
uniprot id: A0A0F7KNG5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1267766:WYH RS12900
gene id: 1267766:WYH_RS12900
uniprot id: A0A0F7KXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1267766:WYH RS14775
gene id: 1267766:WYH_RS14775
uniprot id: A0A0F7KWC6
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS01285
gene id: 1267766:WYH_RS01285
uniprot id: A0A0F7KP20
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1267766:WYH RS05555
gene id: 1267766:WYH_RS05555
uniprot id: A0A0F7KSC5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is located at the dimer interface.

1267766:WYH RS02605
gene id: 1267766:WYH_RS02605
uniprot id: A0A0F7KQX3
names: Similarity
messages: Belongs to the alanine racemase family.

1267766:WYH RS08980
gene id: 1267766:WYH_RS08980
uniprot id: A0A0F7KUK0
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1267766:WYH RS03620
gene id: 1267766:WYH_RS03620
uniprot id: A0A0F7KQF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1267766:WYH RS11935
gene id: 1267766:WYH_RS11935
uniprot id: A0A0F7KWD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS11365
gene id: 1267766:WYH_RS11365
uniprot id: A0A0F7KVY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1267766:WYH RS01240
gene id: 1267766:WYH_RS01240
uniprot id: A0A0F7KP11
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1267766:WYH RS07580
gene id: 1267766:WYH_RS07580
uniprot id: A0A0F7KTK9
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS07720
gene id: 1267766:WYH_RS07720
uniprot id: A0A0F7KPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS01760
gene id: 1267766:WYH_RS01760
uniprot id: A0A0F7KQQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1267766:WYH RS05225
gene id: 1267766:WYH_RS05225
uniprot id: A0A0F7KTH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS03955
gene id: 1267766:WYH_RS03955
uniprot id: A0A0F7KRW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1267766:WYH RS05540
gene id: 1267766:WYH_RS05540
uniprot id: A0A0F7KRE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1267766:WYH RS03090
gene id: 1267766:WYH_RS03090
uniprot id: A0A0F7KR72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1267766:WYH RS06630
gene id: 1267766:WYH_RS06630
uniprot id: A0A0F7KS54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS10100
gene id: 1267766:WYH_RS10100
uniprot id: A0A0F7KU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

1267766:WYH RS12080
gene id: 1267766:WYH_RS12080
uniprot id: A0A0F7KWF7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1267766:WYH RS11685
gene id: 1267766:WYH_RS11685
uniprot id: A0A0F7KUV3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1267766:WYH RS08730
gene id: 1267766:WYH_RS08730
uniprot id: A0A0F7KVL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1267766:WYH RS10685
gene id: 1267766:WYH_RS10685
uniprot id: A0A0F7KVE5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1267766:WYH RS06080
gene id: 1267766:WYH_RS06080
uniprot id: A0A0F7KP32
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1267766:WYH RS03850
gene id: 1267766:WYH_RS03850
uniprot id: A0A0F7KSV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1267766:WYH RS06900
gene id: 1267766:WYH_RS06900
uniprot id: A0A0F7KUJ1
names: Similarity
messages: Belongs to the peptidase A24 family.

1267766:WYH RS11000
gene id: 1267766:WYH_RS11000
uniprot id: A0A0F7KVS0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1267766:WYH RS05270
gene id: 1267766:WYH_RS05270
uniprot id: A0A0F7KR84
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS09005
gene id: 1267766:WYH_RS09005
uniprot id: A0A0F7KUK5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS14530
gene id: 1267766:WYH_RS14530
uniprot id: A0A0F7KXP1
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1267766:WYH RS02865
gene id: 1267766:WYH_RS02865
uniprot id: A0A0F7KQ08
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1267766:WYH RS05455
gene id: 1267766:WYH_RS05455
uniprot id: A0A0F7KSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1267766:WYH RS01700
gene id: 1267766:WYH_RS01700
uniprot id: A0A0F7KRN7
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1267766:WYH RS14390
gene id: 1267766:WYH_RS14390
uniprot id: A0A0F7KYR3
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS01015
gene id: 1267766:WYH_RS01015
uniprot id: A0A0F7KNX5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1267766:WYH RS09450
gene id: 1267766:WYH_RS09450
uniprot id: A0A0F7KTQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS03655
gene id: 1267766:WYH_RS03655
uniprot id: A0A0F7KRP8
names: Similarity
messages: Belongs to the DprA/Smf family.

1267766:WYH RS04690
gene id: 1267766:WYH_RS04690
uniprot id: A0A0F7KT86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1267766:WYH RS10335
gene id: 1267766:WYH_RS10335
uniprot id: A0A0F7KVD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1267766:WYH RS14650
gene id: 1267766:WYH_RS14650
uniprot id: A0A0F7KWA3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1267766:WYH RS01835
gene id: 1267766:WYH_RS01835
uniprot id: A0A0F7KRR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1267766:WYH RS06540
gene id: 1267766:WYH_RS06540
uniprot id: A0A0F7KT24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1267766:WYH RS06985
gene id: 1267766:WYH_RS06985
uniprot id: A0A0F7KPM4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1267766:WYH RS11525
gene id: 1267766:WYH_RS11525
uniprot id: A0A0F7KSJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1267766:WYH RS11990
gene id: 1267766:WYH_RS11990
uniprot id: A0A0F7KST4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1267766:WYH RS03380
gene id: 1267766:WYH_RS03380
uniprot id: A0A0F7KRJ2
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS14030
gene id: 1267766:WYH_RS14030
uniprot id: A0A0F7KU83
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1267766:WYH RS04755
gene id: 1267766:WYH_RS04755
uniprot id: A0A0F7KNC4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1267766:WYH RS04540
gene id: 1267766:WYH_RS04540
uniprot id: A0A0F7KT57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1267766:WYH RS04045
gene id: 1267766:WYH_RS04045
uniprot id: A0A0F7KQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1267766:WYH RS03935
gene id: 1267766:WYH_RS03935
uniprot id: A0A0F7KRL2
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1267766:WYH RS06285
gene id: 1267766:WYH_RS06285
uniprot id: A0A0F7KU55
names: Similarity
messages: Belongs to the threonine synthase family.

1267766:WYH RS04685
gene id: 1267766:WYH_RS04685
uniprot id: A0A0F7KQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1267766:WYH RS00910
gene id: 1267766:WYH_RS00910
uniprot id: A0A0F7KL17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1267766:WYH RS12850
gene id: 1267766:WYH_RS12850
uniprot id: A0A0F7KXV5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1267766:WYH RS13725
gene id: 1267766:WYH_RS13725
uniprot id: A0A0F7KTX0
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS03225
gene id: 1267766:WYH_RS03225
uniprot id: A0A0F7KQ84
names: Similarity
messages: Belongs to the asparagine synthetase family.

1267766:WYH RS14280
gene id: 1267766:WYH_RS14280
uniprot id: A0A0F7KUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm
messages: Part of the Type IV secretion system.

1267766:WYH RS08070
gene id: 1267766:WYH_RS08070
uniprot id: A0A0F7KSW1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS02030
gene id: 1267766:WYH_RS02030
uniprot id: A0A0F7KLS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1267766:WYH RS00645
gene id: 1267766:WYH_RS00645
uniprot id: A0A0F7KQV1
names: Similarity
messages: Belongs to the CFA/CMAS family.

1267766:WYH RS11675
gene id: 1267766:WYH_RS11675
uniprot id: A0A0F7KW40
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1267766:WYH RS06255
gene id: 1267766:WYH_RS06255
uniprot id: A0A0F7KP62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1267766:WYH RS13175
gene id: 1267766:WYH_RS13175
uniprot id: A0A0F7KTH4
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1267766:WYH RS09560
gene id: 1267766:WYH_RS09560
uniprot id: A0A0F7KUX5
names: Similarity
messages: Belongs to the ArsC family.

1267766:WYH RS05110
gene id: 1267766:WYH_RS05110
uniprot id: A0A0F7KR55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1267766:WYH RS11520
gene id: 1267766:WYH_RS11520
uniprot id: A0A0F7KW18
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS02740
gene id: 1267766:WYH_RS02740
uniprot id: A0A0F7KS82
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1267766:WYH RS11700
gene id: 1267766:WYH_RS11700
uniprot id: A0A0F7KW45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1267766:WYH RS02545
gene id: 1267766:WYH_RS02545
uniprot id: A0A0F7KS41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1267766:WYH RS03750
gene id: 1267766:WYH_RS03750
uniprot id: A0A0F7KST0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1267766:WYH RS00215
gene id: 1267766:WYH_RS00215
uniprot id: A0A0F7KNG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS07645
gene id: 1267766:WYH_RS07645
uniprot id: A0A0F7KV01
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS05025
gene id: 1267766:WYH_RS05025
uniprot id: A0A0F7KS17
names: Similarity
messages: Belongs to the BolA/IbaG family.

1267766:WYH RS06800
gene id: 1267766:WYH_RS06800
uniprot id: A0A0F7KS89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1267766:WYH RS00405
gene id: 1267766:WYH_RS00405
uniprot id: A0A0F7KQQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1267766:WYH RS07810
gene id: 1267766:WYH_RS07810
uniprot id: A0A0F7KTQ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1267766:WYH RS09720
gene id: 1267766:WYH_RS09720
uniprot id: A0A0F7KRC0
names: Similarity
messages: Belongs to the RelE toxin family.

1267766:WYH RS01315
gene id: 1267766:WYH_RS01315
uniprot id: A0A0F7KRB9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1267766:WYH RS13685
gene id: 1267766:WYH_RS13685
uniprot id: A0A0F7KYC0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1267766:WYH RS11515
gene id: 1267766:WYH_RS11515
uniprot id: A0A0F7KW47
names: Similarity
messages: Belongs to the peptidase S41A family.

1267766:WYH RS07895
gene id: 1267766:WYH_RS07895
uniprot id: A0A0F7KQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1267766:WYH RS07495
gene id: 1267766:WYH_RS07495
uniprot id: A0A0F7KSK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1267766:WYH RS04650
gene id: 1267766:WYH_RS04650
uniprot id: A0A0F7KRX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1267766:WYH RS00980
gene id: 1267766:WYH_RS00980
uniprot id: A0A0F7KQ55
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

1267766:WYH RS06345
gene id: 1267766:WYH_RS06345
uniprot id: A0A0F7KP82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1267766:WYH RS11440
gene id: 1267766:WYH_RS11440
uniprot id: A0A0F7KVZ6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1267766:WYH RS12965
gene id: 1267766:WYH_RS12965
uniprot id: A0A0F7KVH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS09310
gene id: 1267766:WYH_RS09310
uniprot id: A0A0F7KUL0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1267766:WYH RS09550
gene id: 1267766:WYH_RS09550
uniprot id: A0A0F7KTS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1267766:WYH RS12010
gene id: 1267766:WYH_RS12010
uniprot id: A0A0F7KWA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1267766:WYH RS12775
gene id: 1267766:WYH_RS12775
uniprot id: A0A0F7KXT9
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1267766:WYH RS05245
gene id: 1267766:WYH_RS05245
uniprot id: A0A0F7KR81
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1267766:WYH RS02085
gene id: 1267766:WYH_RS02085
uniprot id: A0A0F7KPJ5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1267766:WYH RS01145
gene id: 1267766:WYH_RS01145
uniprot id: A0A0F7KNY0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1267766:WYH RS04780
gene id: 1267766:WYH_RS04780
uniprot id: A0A0F7KND0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1267766:WYH RS12665
gene id: 1267766:WYH_RS12665
uniprot id: A0A0F7KWL7
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS11630
gene id: 1267766:WYH_RS11630
uniprot id: A0A0F7KUU4
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1267766:WYH RS01985
gene id: 1267766:WYH_RS01985
uniprot id: A0A0F7KPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1267766:WYH RS08820
gene id: 1267766:WYH_RS08820
uniprot id: A0A0F7KVM4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1267766:WYH RS09805
gene id: 1267766:WYH_RS09805
uniprot id: A0A0F7KW67
names: Similarity
messages: Belongs to the virb1 family.

1267766:WYH RS11775
gene id: 1267766:WYH_RS11775
uniprot id: A0A0F7KXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS08985
gene id: 1267766:WYH_RS08985
uniprot id: A0A0F7KUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1267766:WYH RS01800
gene id: 1267766:WYH_RS01800
uniprot id: A0A0F7KLK5
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS05740
gene id: 1267766:WYH_RS05740
uniprot id: A0A0F7KTT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1267766:WYH RS11770
gene id: 1267766:WYH_RS11770
uniprot id: A0A0F7KUW5
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1267766:WYH RS05210
gene id: 1267766:WYH_RS05210
uniprot id: A0A0F7KS50
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1267766:WYH RS12565
gene id: 1267766:WYH_RS12565
uniprot id: A0A0F7KWM1
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1267766:WYH RS07195
gene id: 1267766:WYH_RS07195
uniprot id: A0A0F7KUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1267766:WYH RS01660
gene id: 1267766:WYH_RS01660
uniprot id: A0A0F7KQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS04670
gene id: 1267766:WYH_RS04670
uniprot id: A0A0F7KS96
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1267766:WYH RS08050
gene id: 1267766:WYH_RS08050
uniprot id: A0A0F7KV91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1267766:WYH RS12490
gene id: 1267766:WYH_RS12490
uniprot id: A0A0F7KWL2
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS01855
gene id: 1267766:WYH_RS01855
uniprot id: A0A0F7KRR7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1267766:WYH RS15650
gene id: 1267766:WYH_RS15650
uniprot id: A0A0F7KV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1267766:WYH RS12275
gene id: 1267766:WYH_RS12275
uniprot id: A0A0F7KWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1267766:WYH RS04145
gene id: 1267766:WYH_RS04145
uniprot id: A0A0F7KQQ9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1267766:WYH RS01160
gene id: 1267766:WYH_RS01160
uniprot id: A0A0F7KQ83
names: Similarity
messages: Belongs to the fabD family.

1267766:WYH RS14060
gene id: 1267766:WYH_RS14060
uniprot id: A0A0F7KW10
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1267766:WYH RS11270
gene id: 1267766:WYH_RS11270
uniprot id: A0A0F7KVU6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1267766:WYH RS15190
gene id: 1267766:WYH_RS15190
uniprot id: A0A0F7KZ36
names: Subunit
messages: Homodimer.

1267766:WYH RS02485
gene id: 1267766:WYH_RS02485
uniprot id: A0A0F7KLZ5
names: Similarity
messages: Belongs to the GST superfamily.

1267766:WYH RS06305
gene id: 1267766:WYH_RS06305
uniprot id: A0A0F7KRU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1267766:WYH RS00425
gene id: 1267766:WYH_RS00425
uniprot id: A0A0F7KNK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1267766:WYH RS12875
gene id: 1267766:WYH_RS12875
uniprot id: A0A0F7KXW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1267766:WYH RS05755
gene id: 1267766:WYH_RS05755
uniprot id: A0A0F7KNY4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS03070
gene id: 1267766:WYH_RS03070
uniprot id: A0A0F7KM82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1267766:WYH RS09045
gene id: 1267766:WYH_RS09045
uniprot id: A0A0F7KTI1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1267766:WYH RS07255
gene id: 1267766:WYH_RS07255
uniprot id: A0A0F7KTF2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1267766:WYH RS11010
gene id: 1267766:WYH_RS11010
uniprot id: A0A0F7KS36
names: Similarity
messages: Belongs to the RNase T2 family.

1267766:WYH RS01640
gene id: 1267766:WYH_RS01640
uniprot id: A0A0F7KLH6
names: Similarity
messages: Belongs to the tannase family.

1267766:WYH RS16330
gene id: 1267766:WYH_RS16330
uniprot id: A0A0F7KVM8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1267766:WYH RS01460
gene id: 1267766:WYH_RS01460
uniprot id: A0A0F7KRF4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

1267766:WYH RS14460
gene id: 1267766:WYH_RS14460
uniprot id: A0A0F7KUE9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1267766:WYH RS04760
gene id: 1267766:WYH_RS04760
uniprot id: A0A0F7KR12
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1267766:WYH RS05480
gene id: 1267766:WYH_RS05480
uniprot id: A0A0F7KSA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1267766:WYH RS04955
gene id: 1267766:WYH_RS04955
uniprot id: A0A0F7KNG1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1267766:WYH RS07395
gene id: 1267766:WYH_RS07395
uniprot id: A0A0F7KSI5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS11800
gene id: 1267766:WYH_RS11800
uniprot id: A0A0F7KUX0
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1267766:WYH RS16295
gene id: 1267766:WYH_RS16295
uniprot id: A0A0F7KZS8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1267766:WYH RS13605
gene id: 1267766:WYH_RS13605
uniprot id: A0A0F7KVP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1267766:WYH RS11150
gene id: 1267766:WYH_RS11150
uniprot id: A0A0F7KVS3
names: Similarity
messages: Belongs to the CutA family.

1267766:WYH RS15925
gene id: 1267766:WYH_RS15925
uniprot id: A0A0F7KYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1267766:WYH RS16245
gene id: 1267766:WYH_RS16245
uniprot id: A0A0F7KZR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1267766:WYH RS09570
gene id: 1267766:WYH_RS09570
uniprot id: A0A0F7KR74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1267766:WYH RS12160
gene id: 1267766:WYH_RS12160
uniprot id: A0A0F7KWC7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1267766:WYH RS04120
gene id: 1267766:WYH_RS04120
uniprot id: A0A0F7KQQ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS07005
gene id: 1267766:WYH_RS07005
uniprot id: A0A0F7KTB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1267766:WYH RS06375
gene id: 1267766:WYH_RS06375
uniprot id: A0A0F7KRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1267766:WYH RS10985
gene id: 1267766:WYH_RS10985
uniprot id: A0A0F7KS32
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1267766:WYH RS11280
gene id: 1267766:WYH_RS11280
uniprot id: A0A0F7KUN2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS00145
gene id: 1267766:WYH_RS00145
uniprot id: A0A0F7KQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS14720
gene id: 1267766:WYH_RS14720
uniprot id: A0A0F7KUI4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1267766:WYH RS14110
gene id: 1267766:WYH_RS14110
uniprot id: A0A0F7KW17
names: Similarity
messages: Belongs to the UPF0311 family.

1267766:WYH RS13155
gene id: 1267766:WYH_RS13155
uniprot id: A0A0F7KRV2
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1267766:WYH RS13795
gene id: 1267766:WYH_RS13795
uniprot id: A0A0F7KTY6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1267766:WYH RS02385
gene id: 1267766:WYH_RS02385
uniprot id: A0A0F7KLX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1267766:WYH RS01290
gene id: 1267766:WYH_RS01290
uniprot id: A0A0F7KRB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS06415
gene id: 1267766:WYH_RS06415
uniprot id: A0A0F7KU81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1267766:WYH RS12315
gene id: 1267766:WYH_RS12315
uniprot id: A0A0F7KXJ9
names: Similarity
messages: Belongs to the TPP enzyme family.

1267766:WYH RS00550
gene id: 1267766:WYH_RS00550
uniprot id: A0A0F7KNN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1267766:WYH RS06635
gene id: 1267766:WYH_RS06635
uniprot id: A0A0F7KUE4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS03410
gene id: 1267766:WYH_RS03410
uniprot id: A0A0F7KRB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1267766:WYH RS00150
gene id: 1267766:WYH_RS00150
uniprot id: A0A0F7KPP1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1267766:WYH RS09905
gene id: 1267766:WYH_RS09905
uniprot id: A0A0F7KTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS12560
gene id: 1267766:WYH_RS12560
uniprot id: A0A0F7KXP2
names: Similarity
messages: Belongs to the carbamate kinase family.

1267766:WYH RS02405
gene id: 1267766:WYH_RS02405
uniprot id: A0A0F7KQT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1267766:WYH RS08185
gene id: 1267766:WYH_RS08185
uniprot id: A0A0F7KU54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1267766:WYH RS04115
gene id: 1267766:WYH_RS04115
uniprot id: A0A0F7KMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1267766:WYH RS03175
gene id: 1267766:WYH_RS03175
uniprot id: A0A0F7KQ73
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1267766:WYH RS05115
gene id: 1267766:WYH_RS05115
uniprot id: A0A0F7KTF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1267766:WYH RS15640
gene id: 1267766:WYH_RS15640
uniprot id: A0A0F7KY68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

1267766:WYH RS00450
gene id: 1267766:WYH_RS00450
uniprot id: A0A0F7KNL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1267766:WYH RS05055
gene id: 1267766:WYH_RS05055
uniprot id: A0A0F7KNH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1267766:WYH RS01045
gene id: 1267766:WYH_RS01045
uniprot id: A0A0F7KNX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1267766:WYH RS11885
gene id: 1267766:WYH_RS11885
uniprot id: A0A0F7KWC0
names: Similarity
messages: Belongs to the FBPase class 2 family.

1267766:WYH RS04420
gene id: 1267766:WYH_RS04420
uniprot id: A0A0F7KS52
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1267766:WYH RS12830
gene id: 1267766:WYH_RS12830
uniprot id: A0A0F7KWS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1267766:WYH RS09915
gene id: 1267766:WYH_RS09915
uniprot id: A0A0F7KV46
names: Similarity
messages: Belongs to the YggT family.

1267766:WYH RS00995
gene id: 1267766:WYH_RS00995
uniprot id: A0A0F7KR24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1267766:WYH RS06735
gene id: 1267766:WYH_RS06735
uniprot id: A0A0F7KUG1
names: Similarity
messages: Belongs to the peptidase M17 family.

1267766:WYH RS00440
gene id: 1267766:WYH_RS00440
uniprot id: A0A0F7KPW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1267766:WYH RS05200
gene id: 1267766:WYH_RS05200
uniprot id: A0A0F7KTH2
names: Similarity
messages: Belongs to the peptidase M16 family.

1267766:WYH RS00380
gene id: 1267766:WYH_RS00380
uniprot id: A0A0F7KQQ2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1267766:WYH RS04510
gene id: 1267766:WYH_RS04510
uniprot id: A0A0F7KQW8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1267766:WYH RS00640
gene id: 1267766:WYH_RS00640
uniprot id: A0A0F7KNQ8
names: Similarity
messages: Belongs to the CFA/CMAS family.

1267766:WYH RS11660
gene id: 1267766:WYH_RS11660
uniprot id: A0A0F7KUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1267766:WYH RS05275
gene id: 1267766:WYH_RS05275
uniprot id: A0A0F7KTI6
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS14150
gene id: 1267766:WYH_RS14150
uniprot id: A0A0F7KXH8
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS08015
gene id: 1267766:WYH_RS08015
uniprot id: A0A0F7KQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1267766:WYH RS13280
gene id: 1267766:WYH_RS13280
uniprot id: A0A0F7KVL8
names: Similarity
messages: Belongs to the GSP E family.

1267766:WYH RS03660
gene id: 1267766:WYH_RS03660
uniprot id: A0A0F7KRG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1267766:WYH RS11695
gene id: 1267766:WYH_RS11695
uniprot id: A0A0F7KW85
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1267766:WYH RS08480
gene id: 1267766:WYH_RS08480
uniprot id: A0A0F7KQG1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1267766:WYH RS04405
gene id: 1267766:WYH_RS04405
uniprot id: A0A0F7KN33
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1267766:WYH RS08230
gene id: 1267766:WYH_RS08230
uniprot id: A0A0F7KTY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1267766:WYH RS03450
gene id: 1267766:WYH_RS03450
uniprot id: A0A0F7KQC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1267766:WYH RS05205
gene id: 1267766:WYH_RS05205
uniprot id: A0A0F7KSI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1267766:WYH RS09555
gene id: 1267766:WYH_RS09555
uniprot id: A0A0F7KW21
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1267766:WYH RS00385
gene id: 1267766:WYH_RS00385
uniprot id: A0A0F7KPT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1267766:WYH RS06595
gene id: 1267766:WYH_RS06595
uniprot id: A0A0F7KT40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1267766:WYH RS00155
gene id: 1267766:WYH_RS00155
uniprot id: A0A0F7KPS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1267766:WYH RS05640
gene id: 1267766:WYH_RS05640
uniprot id: A0A0F7KTR5
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

1267766:WYH RS09270
gene id: 1267766:WYH_RS09270
uniprot id: A0A0F7KTM5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1267766:WYH RS07790
gene id: 1267766:WYH_RS07790
uniprot id: A0A0F7KQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1267766:WYH RS05600
gene id: 1267766:WYH_RS05600
uniprot id: A0A0F7KSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1267766:WYH RS02375
gene id: 1267766:WYH_RS02375
uniprot id: A0A0F7KR15
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1267766:WYH RS03100
gene id: 1267766:WYH_RS03100
uniprot id: A0A0F7KQ57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1267766:WYH RS14235
gene id: 1267766:WYH_RS14235
uniprot id: A0A0F7KW36
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1267766:WYH RS06860
gene id: 1267766:WYH_RS06860
uniprot id: A0A0F7KTH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1267766:WYH RS05185
gene id: 1267766:WYH_RS05185
uniprot id: A0A0F7KS44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS08765
gene id: 1267766:WYH_RS08765
uniprot id: A0A0F7KQK9
names: Similarity
messages: Belongs to the thioredoxin family.

1267766:WYH RS12410
gene id: 1267766:WYH_RS12410
uniprot id: A0A0F7KWK1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1267766:WYH RS13645
gene id: 1267766:WYH_RS13645
uniprot id: A0A0F7KX56
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1267766:WYH RS16025
gene id: 1267766:WYH_RS16025
uniprot id: A0A0F7KYE9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1267766:WYH RS03525
gene id: 1267766:WYH_RS03525
uniprot id: A0A0F7KQE0
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1267766:WYH RS14050
gene id: 1267766:WYH_RS14050
uniprot id: A0A0F7KXG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS08810
gene id: 1267766:WYH_RS08810
uniprot id: A0A0F7KU74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS15130
gene id: 1267766:WYH_RS15130
uniprot id: A0A0F7KUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1267766:WYH RS02970
gene id: 1267766:WYH_RS02970
uniprot id: A0A0F7KM67
names: Similarity
messages: Belongs to the TrpC family.

1267766:WYH RS14885
gene id: 1267766:WYH_RS14885
uniprot id: A0A0F7KYY9
names: Similarity
messages: Belongs to the lycopene cyclase family.

1267766:WYH RS12705
gene id: 1267766:WYH_RS12705
uniprot id: A0A0F7KWQ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS14505
gene id: 1267766:WYH_RS14505
uniprot id: A0A0F7KXN7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1267766:WYH RS01605
gene id: 1267766:WYH_RS01605
uniprot id: A0A0F7KQM8
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS02600
gene id: 1267766:WYH_RS02600
uniprot id: A0A0F7KR65
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS06650
gene id: 1267766:WYH_RS06650
uniprot id: A0A0F7KPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1267766:WYH RS11265
gene id: 1267766:WYH_RS11265
uniprot id: A0A0F7KVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1267766:WYH RS14440
gene id: 1267766:WYH_RS14440
uniprot id: A0A0F7KW72
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1267766:WYH RS02945
gene id: 1267766:WYH_RS02945
uniprot id: A0A0F7KM64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1267766:WYH RS00435
gene id: 1267766:WYH_RS00435
uniprot id: A0A0F7KPU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1267766:WYH RS07160
gene id: 1267766:WYH_RS07160
uniprot id: A0A0F7KPP8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1267766:WYH RS01390
gene id: 1267766:WYH_RS01390
uniprot id: A0A0F7KRD6
names: Similarity
messages: Belongs to the CFA/CMAS family.

1267766:WYH RS10130
gene id: 1267766:WYH_RS10130
uniprot id: A0A0F7KWD3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1267766:WYH RS12240
gene id: 1267766:WYH_RS12240
uniprot id: A0A0F7KWH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1267766:WYH RS04005
gene id: 1267766:WYH_RS04005
uniprot id: A0A0F7KRW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1267766:WYH RS13680
gene id: 1267766:WYH_RS13680
uniprot id: A0A0F7KVS2
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1267766:WYH RS11295
gene id: 1267766:WYH_RS11295
uniprot id: A0A0F7KVV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS13070
gene id: 1267766:WYH_RS13070
uniprot id: A0A0F7KY01
names: Similarity
messages: Belongs to the universal stress protein A family.

1267766:WYH RS02965
gene id: 1267766:WYH_RS02965
uniprot id: A0A0F7KR44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS04080
gene id: 1267766:WYH_RS04080
uniprot id: A0A0F7KRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1267766:WYH RS06485
gene id: 1267766:WYH_RS06485
uniprot id: A0A0F7KT71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1267766:WYH RS05870
gene id: 1267766:WYH_RS05870
uniprot id: A0A0F7KTW1
names: Similarity
messages: Belongs to the UPF0311 family.

1267766:WYH RS04400
gene id: 1267766:WYH_RS04400
uniprot id: A0A0F7KRT7
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS04740
gene id: 1267766:WYH_RS04740
uniprot id: A0A0F7KT92
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1267766:WYH RS05560
gene id: 1267766:WYH_RS05560
uniprot id: A0A0F7KNT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1267766:WYH RS11235
gene id: 1267766:WYH_RS11235
uniprot id: A0A0F7KWZ2
names: Similarity
messages: Belongs to the HesB/IscA family.

1267766:WYH RS02060
gene id: 1267766:WYH_RS02060
uniprot id: A0A0F7KPI9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1267766:WYH RS05620
gene id: 1267766:WYH_RS05620
uniprot id: A0A0F7KSS0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1267766:WYH RS00470
gene id: 1267766:WYH_RS00470
uniprot id: A0A0F7KKQ7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1267766:WYH RS02220
gene id: 1267766:WYH_RS02220
uniprot id: A0A0F7KRY7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1267766:WYH RS11120
gene id: 1267766:WYH_RS11120
uniprot id: A0A0F7KVU0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1267766:WYH RS05630
gene id: 1267766:WYH_RS05630
uniprot id: A0A0F7KNV1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1267766:WYH RS03075
gene id: 1267766:WYH_RS03075
uniprot id: A0A0F7KQ51
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1267766:WYH RS17010
gene id: 1267766:WYH_RS17010
uniprot id: A0A0F7KSY6
names: Similarity
messages: Belongs to the SBNO family.

1267766:WYH RS16125
gene id: 1267766:WYH_RS16125
uniprot id: A0A0F7KZN7
names: Similarity
messages: Belongs to the universal stress protein A family.

1267766:WYH RS00475
gene id: 1267766:WYH_RS00475
uniprot id: A0A0F7KNM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1267766:WYH RS15590
gene id: 1267766:WYH_RS15590
uniprot id: A0A0F7KY59
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1267766:WYH RS14690
gene id: 1267766:WYH_RS14690
uniprot id: A0A0F7KXQ8
names: Similarity
messages: Belongs to the fructosamine kinase family.

1267766:WYH RS03085
gene id: 1267766:WYH_RS03085
uniprot id: A0A0F7KRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1267766:WYH RS01935
gene id: 1267766:WYH_RS01935
uniprot id: A0A0F7KPG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1267766:WYH RS09540
gene id: 1267766:WYH_RS09540
uniprot id: A0A0F7KUP5
names: Similarity
messages: Belongs to the aspartokinase family.

1267766:WYH RS15655
gene id: 1267766:WYH_RS15655
uniprot id: A0A0F7KWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS00900
gene id: 1267766:WYH_RS00900
uniprot id: A0A0F7KQ42
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS14260
gene id: 1267766:WYH_RS14260
uniprot id: A0A0F7KW41
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1267766:WYH RS15870
gene id: 1267766:WYH_RS15870
uniprot id: A0A0F7KV69
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1267766:WYH RS03460
gene id: 1267766:WYH_RS03460
uniprot id: A0A0F7KRK4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1267766:WYH RS15070
gene id: 1267766:WYH_RS15070
uniprot id: A0A0F7KXV6
names: Similarity
messages: Belongs to the peptidase S8 family.

1267766:WYH RS08970
gene id: 1267766:WYH_RS08970
uniprot id: A0A0F7KTC8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1267766:WYH RS10235
gene id: 1267766:WYH_RS10235
uniprot id: A0A0F7KVB0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1267766:WYH RS02530
gene id: 1267766:WYH_RS02530
uniprot id: A0A0F7KQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1267766:WYH RS01170
gene id: 1267766:WYH_RS01170
uniprot id: A0A0F7KNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1267766:WYH RS13170
gene id: 1267766:WYH_RS13170
uniprot id: A0A0F7KWW4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1267766:WYH RS03470
gene id: 1267766:WYH_RS03470
uniprot id: A0A0F7KMG9
names: Similarity
messages: Belongs to the thioredoxin family.

1267766:WYH RS12540
gene id: 1267766:WYH_RS12540
uniprot id: A0A0F7KWL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1267766:WYH RS11105
gene id: 1267766:WYH_RS11105
uniprot id: A0A0F7KS60
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1267766:WYH RS15320
gene id: 1267766:WYH_RS15320
uniprot id: A0A0F7KWS9
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS00410
gene id: 1267766:WYH_RS00410
uniprot id: A0A0F7KPU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1267766:WYH RS09575
gene id: 1267766:WYH_RS09575
uniprot id: A0A0F7KTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1267766:WYH RS12515
gene id: 1267766:WYH_RS12515
uniprot id: A0A0F7KWL5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1267766:WYH RS12520
gene id: 1267766:WYH_RS12520
uniprot id: A0A0F7KWJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1267766:WYH RS11915
gene id: 1267766:WYH_RS11915
uniprot id: A0A0F7KW82
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1267766:WYH RS00120
gene id: 1267766:WYH_RS00120
uniprot id: A0A0F7KQK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1267766:WYH RS05525
gene id: 1267766:WYH_RS05525
uniprot id: A0A0F7KSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1267766:WYH RS14930
gene id: 1267766:WYH_RS14930
uniprot id: A0A0F7KWF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1267766:WYH RS01545
gene id: 1267766:WYH_RS01545
uniprot id: A0A0F7KQL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS15680
gene id: 1267766:WYH_RS15680
uniprot id: A0A0F7KWZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1267766:WYH RS11570
gene id: 1267766:WYH_RS11570
uniprot id: A0A0F7KW26
names: Similarity
messages: Belongs to the PhzF family.

1267766:WYH RS05075
gene id: 1267766:WYH_RS05075
uniprot id: A0A0F7KS26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1267766:WYH RS03510
gene id: 1267766:WYH_RS03510
uniprot id: A0A0F7KRL3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1267766:WYH RS08100
gene id: 1267766:WYH_RS08100
uniprot id: A0A0F7KVA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1267766:WYH RS09130
gene id: 1267766:WYH_RS09130
uniprot id: A0A0F7KUQ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1267766:WYH RS07680
gene id: 1267766:WYH_RS07680
uniprot id: A0A0F7KTN0
names: Similarity
messages: Belongs to the IlvD/Edd family.

1267766:WYH RS12145
gene id: 1267766:WYH_RS12145
uniprot id: A0A0F7KV33
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS09510
gene id: 1267766:WYH_RS09510
uniprot id: A0A0F7KUW7
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS04700
gene id: 1267766:WYH_RS04700
uniprot id: A0A0F7KRX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1267766:WYH RS07990
gene id: 1267766:WYH_RS07990
uniprot id: A0A0F7KQ52
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1267766:WYH RS02255
gene id: 1267766:WYH_RS02255
uniprot id: A0A0F7KQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS10895
gene id: 1267766:WYH_RS10895
uniprot id: A0A0F7KVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1267766:WYH RS15180
gene id: 1267766:WYH_RS15180
uniprot id: A0A0F7KUS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1267766:WYH RS11670
gene id: 1267766:WYH_RS11670
uniprot id: A0A0F7KW80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1267766:WYH RS16340
gene id: 1267766:WYH_RS16340
uniprot id: A0A0F7KZT8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1267766:WYH RS05595
gene id: 1267766:WYH_RS05595
uniprot id: A0A0F7KTQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1267766:WYH RS06215
gene id: 1267766:WYH_RS06215
uniprot id: A0A0F7KU40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1267766:WYH RS01965
gene id: 1267766:WYH_RS01965
uniprot id: A0A0F7KRT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1267766:WYH RS09525
gene id: 1267766:WYH_RS09525
uniprot id: A0A0F7KTS4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1267766:WYH RS03575
gene id: 1267766:WYH_RS03575
uniprot id: A0A0F7KSP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS01385
gene id: 1267766:WYH_RS01385
uniprot id: A0A0F7KP34
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1267766:WYH RS11645
gene id: 1267766:WYH_RS11645
uniprot id: A0A0F7KW75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1267766:WYH RS05775
gene id: 1267766:WYH_RS05775
uniprot id: A0A0F7KSG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1267766:WYH RS09880
gene id: 1267766:WYH_RS09880
uniprot id: A0A0F7KTY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1267766:WYH RS13135
gene id: 1267766:WYH_RS13135
uniprot id: A0A0F7KVK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1267766:WYH RS02585
gene id: 1267766:WYH_RS02585
uniprot id: A0A0F7KM16
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1267766:WYH RS02155
gene id: 1267766:WYH_RS02155
uniprot id: A0A0F7KLU1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1267766:WYH RS13860
gene id: 1267766:WYH_RS13860
uniprot id: A0A0F7KVV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1267766:WYH RS17260
gene id: 1267766:WYH_RS17260
uniprot id: A0A0F7KSW9
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS08040
gene id: 1267766:WYH_RS08040
uniprot id: A0A0F7KQ61
names: Similarity
messages: Belongs to the Tim44 family.

1267766:WYH RS13995
gene id: 1267766:WYH_RS13995
uniprot id: A0A0F7KXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1267766:WYH RS04055
gene id: 1267766:WYH_RS04055
uniprot id: A0A0F7KRN0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1267766:WYH RS10150
gene id: 1267766:WYH_RS10150
uniprot id: A0A0F7KU32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS03185
gene id: 1267766:WYH_RS03185
uniprot id: A0A0F7KRG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1267766:WYH RS06130
gene id: 1267766:WYH_RS06130
uniprot id: A0A0F7KP39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1267766:WYH RS00020
gene id: 1267766:WYH_RS00020
uniprot id: A0A0F7KYF3
names: Similarity
messages: Belongs to the BolA/IbaG family.

1267766:WYH RS04075
gene id: 1267766:WYH_RS04075
uniprot id: A0A0F7KSZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1267766:WYH RS11290
gene id: 1267766:WYH_RS11290
uniprot id: A0A0F7KVX4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1267766:WYH RS06840
gene id: 1267766:WYH_RS06840
uniprot id: A0A0F7KT85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1267766:WYH RS16290
gene id: 1267766:WYH_RS16290
uniprot id: A0A0F7KXE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1267766:WYH RS15440
gene id: 1267766:WYH_RS15440
uniprot id: A0A0F7KY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1267766:WYH RS02495
gene id: 1267766:WYH_RS02495
uniprot id: A0A0F7KS31
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1267766:WYH RS07265
gene id: 1267766:WYH_RS07265
uniprot id: A0A0F7KSG7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1267766:WYH RS13865
gene id: 1267766:WYH_RS13865
uniprot id: A0A0F7KYF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1267766:WYH RS02115
gene id: 1267766:WYH_RS02115
uniprot id: A0A0F7KRW2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1267766:WYH RS04230
gene id: 1267766:WYH_RS04230
uniprot id: A0A0F7KS23
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1267766:WYH RS06970
gene id: 1267766:WYH_RS06970
uniprot id: A0A0F7KSB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1267766:WYH RS07030
gene id: 1267766:WYH_RS07030
uniprot id: A0A0F7KTB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1267766:WYH RS05050
gene id: 1267766:WYH_RS05050
uniprot id: A0A0F7KS21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1267766:WYH RS04970
gene id: 1267766:WYH_RS04970
uniprot id: A0A0F7KSF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1267766:WYH RS15245
gene id: 1267766:WYH_RS15245
uniprot id: A0A0F7KWR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS06040
gene id: 1267766:WYH_RS06040
uniprot id: A0A0F7KRN4
names: Similarity
messages: Belongs to the PhoH family.

1267766:WYH RS14515
gene id: 1267766:WYH_RS14515
uniprot id: A0A0F7KW87
names: Similarity
messages: Belongs to the UPF0174 family.

1267766:WYH RS04950
gene id: 1267766:WYH_RS04950
uniprot id: A0A0F7KS06
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1267766:WYH RS04345
gene id: 1267766:WYH_RS04345
uniprot id: A0A0F7KN24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1267766:WYH RS12215
gene id: 1267766:WYH_RS12215
uniprot id: A0A0F7KXI4
names: Similarity
messages: Belongs to the RelE toxin family.

1267766:WYH RS03400
gene id: 1267766:WYH_RS03400
uniprot id: A0A0F7KSK6
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1267766:WYH RS03800
gene id: 1267766:WYH_RS03800
uniprot id: A0A0F7KRS9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS02390
gene id: 1267766:WYH_RS02390
uniprot id: A0A0F7KPR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1267766:WYH RS07060
gene id: 1267766:WYH_RS07060
uniprot id: A0A0F7KPN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS14395
gene id: 1267766:WYH_RS14395
uniprot id: A0A0F7KXK0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1267766:WYH RS10195
gene id: 1267766:WYH_RS10195
uniprot id: A0A0F7KRK9
names: Similarity
messages: Belongs to the peptidase M24B family.

1267766:WYH RS07615
gene id: 1267766:WYH_RS07615
uniprot id: A0A0F7KSM7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1267766:WYH RS03080
gene id: 1267766:WYH_RS03080
uniprot id: A0A0F7KSE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1267766:WYH RS01355
gene id: 1267766:WYH_RS01355
uniprot id: A0A0F7KLA8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS10920
gene id: 1267766:WYH_RS10920
uniprot id: A0A0F7KVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1267766:WYH RS07665
gene id: 1267766:WYH_RS07665
uniprot id: A0A0F7KSN7
names: Subcellular Location Annotation
messages: Cytoplasm

1267766:WYH RS11420
gene id: 1267766:WYH_RS11420
uniprot id: A0A0F7KVX7
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS13130
gene id: 1267766:WYH_RS13130
uniprot id: A0A0F7KWV4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1267766:WYH RS15970
gene id: 1267766:WYH_RS15970
uniprot id: A0A0F7KZJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1267766:WYH RS04770
gene id: 1267766:WYH_RS04770
uniprot id: A0A0F7KSB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1267766:WYH RS13615
gene id: 1267766:WYH_RS13615
uniprot id: A0A0F7KX68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1267766:WYH RS04805
gene id: 1267766:WYH_RS04805
uniprot id: A0A0F7KND5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1267766:WYH RS03520
gene id: 1267766:WYH_RS03520
uniprot id: A0A0F7KMH9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1267766:WYH RS07190
gene id: 1267766:WYH_RS07190
uniprot id: A0A0F7KSF4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1267766:WYH RS05000
gene id: 1267766:WYH_RS05000
uniprot id: A0A0F7KS14
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1267766:WYH RS06465
gene id: 1267766:WYH_RS06465
uniprot id: A0A0F7KSV8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1267766:WYH RS08440
gene id: 1267766:WYH_RS08440
uniprot id: A0A0F7KVG5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1267766:WYH RS06930
gene id: 1267766:WYH_RS06930
uniprot id: A0A0F7KTI5
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS08960
gene id: 1267766:WYH_RS08960
uniprot id: A0A0F7KUA9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1267766:WYH RS08345
gene id: 1267766:WYH_RS08345
uniprot id: A0A0F7KQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1267766:WYH RS13165
gene id: 1267766:WYH_RS13165
uniprot id: A0A0F7KWZ0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1267766:WYH RS11305
gene id: 1267766:WYH_RS11305
uniprot id: A0A0F7KUN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS06420
gene id: 1267766:WYH_RS06420
uniprot id: A0A0F7KT56
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS06315
gene id: 1267766:WYH_RS06315
uniprot id: A0A0F7KSS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1267766:WYH RS04855
gene id: 1267766:WYH_RS04855
uniprot id: A0A0F7KNE5
names: Similarity
messages: Belongs to the peptidase C56 family.

1267766:WYH RS13990
gene id: 1267766:WYH_RS13990
uniprot id: A0A0F7KYL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS01405
gene id: 1267766:WYH_RS01405
uniprot id: A0A0F7KLB7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1267766:WYH RS11600
gene id: 1267766:WYH_RS11600
uniprot id: A0A0F7KSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1267766:WYH RS02990
gene id: 1267766:WYH_RS02990
uniprot id: A0A0F7KR49
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1267766:WYH RS04235
gene id: 1267766:WYH_RS04235
uniprot id: A0A0F7KRR2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1267766:WYH RS02410
gene id: 1267766:WYH_RS02410
uniprot id: A0A0F7KLY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1267766:WYH RS01000
gene id: 1267766:WYH_RS01000
uniprot id: A0A0F7KQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1267766:WYH RS14000
gene id: 1267766:WYH_RS14000
uniprot id: A0A0F7KXF2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1267766:WYH RS05930
gene id: 1267766:WYH_RS05930
uniprot id: A0A0F7KSJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS07980
gene id: 1267766:WYH_RS07980
uniprot id: A0A0F7KV75
names: Similarity
messages: Belongs to the YkuD family.

1267766:WYH RS04020
gene id: 1267766:WYH_RS04020
uniprot id: A0A0F7KQN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1267766:WYH RS02555
gene id: 1267766:WYH_RS02555
uniprot id: A0A0F7KQW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1267766:WYH RS14290
gene id: 1267766:WYH_RS14290
uniprot id: A0A0F7KYQ1
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1267766:WYH RS03845
gene id: 1267766:WYH_RS03845
uniprot id: A0A0F7KQH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1267766:WYH RS09925
gene id: 1267766:WYH_RS09925
uniprot id: A0A0F7KRG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1267766:WYH RS06610
gene id: 1267766:WYH_RS06610
uniprot id: A0A0F7KUE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS16210
gene id: 1267766:WYH_RS16210
uniprot id: A0A0F7KYL7
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS14095
gene id: 1267766:WYH_RS14095
uniprot id: A0A0F7KXF4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1267766:WYH RS00370
gene id: 1267766:WYH_RS00370
uniprot id: A0A0F7KKN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1267766:WYH RS15810
gene id: 1267766:WYH_RS15810
uniprot id: A0A0F7KZG3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1267766:WYH RS10780
gene id: 1267766:WYH_RS10780
uniprot id: A0A0F7KVG6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1267766:WYH RS05475
gene id: 1267766:WYH_RS05475
uniprot id: A0A0F7KSP0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS07740
gene id: 1267766:WYH_RS07740
uniprot id: A0A0F7KTP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1267766:WYH RS03795
gene id: 1267766:WYH_RS03795
uniprot id: A0A0F7KSU3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS07845
gene id: 1267766:WYH_RS07845
uniprot id: A0A0F7KSR9
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS13700
gene id: 1267766:WYH_RS13700
uniprot id: A0A0F7KTW4
names: Similarity
messages: Belongs to the TPP enzyme family.

1267766:WYH RS00515
gene id: 1267766:WYH_RS00515
uniprot id: A0A0F7KPX7
names: Similarity
messages: Belongs to the peptidase S9A family.

1267766:WYH RS06925
gene id: 1267766:WYH_RS06925
uniprot id: A0A0F7KUJ5
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS06825
gene id: 1267766:WYH_RS06825
uniprot id: A0A0F7KS94
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1267766:WYH RS05565
gene id: 1267766:WYH_RS05565
uniprot id: A0A0F7KRF2
names: Similarity
messages: Belongs to the universal stress protein A family.

1267766:WYH RS10250
gene id: 1267766:WYH_RS10250
uniprot id: A0A0F7KU47
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1267766:WYH RS12955
gene id: 1267766:WYH_RS12955
uniprot id: A0A0F7KWR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1267766:WYH RS00415
gene id: 1267766:WYH_RS00415
uniprot id: A0A0F7KPW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1267766:WYH RS01175
gene id: 1267766:WYH_RS01175
uniprot id: A0A0F7KR68
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1267766:WYH RS14295
gene id: 1267766:WYH_RS14295
uniprot id: A0A0F7KXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

1267766:WYH RS12760
gene id: 1267766:WYH_RS12760
uniprot id: A0A0F7KWN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS08365
gene id: 1267766:WYH_RS08365
uniprot id: A0A0F7KTZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1267766:WYH RS04475
gene id: 1267766:WYH_RS04475
uniprot id: A0A0F7KRU9
names: Similarity
messages: Belongs to the PrpD family.

1267766:WYH RS15515
gene id: 1267766:WYH_RS15515
uniprot id: A0A0F7KY46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1267766:WYH RS04085
gene id: 1267766:WYH_RS04085
uniprot id: A0A0F7KRN5
names: Similarity
messages: Belongs to the Skp family.

1267766:WYH RS07750
gene id: 1267766:WYH_RS07750
uniprot id: A0A0F7KSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1267766:WYH RS02615
gene id: 1267766:WYH_RS02615
uniprot id: A0A0F7KPV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS05375
gene id: 1267766:WYH_RS05375
uniprot id: A0A0F7KSM0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1267766:WYH RS06675
gene id: 1267766:WYH_RS06675
uniprot id: A0A0F7KPI4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1267766:WYH RS06745
gene id: 1267766:WYH_RS06745
uniprot id: A0A0F7KT68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1267766:WYH RS14275
gene id: 1267766:WYH_RS14275
uniprot id: A0A0F7KXK1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1267766:WYH RS14550
gene id: 1267766:WYH_RS14550
uniprot id: A0A0F7KYT7
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS05920
gene id: 1267766:WYH_RS05920
uniprot id: A0A0F7KTX1
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1267766:WYH RS11330
gene id: 1267766:WYH_RS11330
uniprot id: A0A0F7KUP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1267766:WYH RS00085
gene id: 1267766:WYH_RS00085
uniprot id: A0A0F7KYG7
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS12645
gene id: 1267766:WYH_RS12645
uniprot id: A0A0F7KWL4
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1267766:WYH RS15065
gene id: 1267766:WYH_RS15065
uniprot id: A0A0F7KZ22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1267766:WYH RS08020
gene id: 1267766:WYH_RS08020
uniprot id: A0A0F7KSV0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1267766:WYH RS01680
gene id: 1267766:WYH_RS01680
uniprot id: A0A0F7KQP2
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS02280
gene id: 1267766:WYH_RS02280
uniprot id: A0A0F7KQR9
names: Similarity
messages: Belongs to the tannase family.

1267766:WYH RS05585
gene id: 1267766:WYH_RS05585
uniprot id: A0A0F7KNU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1267766:WYH RS07520
gene id: 1267766:WYH_RS07520
uniprot id: A0A0F7KUX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1267766:WYH RS04590
gene id: 1267766:WYH_RS04590
uniprot id: A0A0F7KT67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1267766:WYH RS03895
gene id: 1267766:WYH_RS03895
uniprot id: A0A0F7KSW3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1267766:WYH RS00635
gene id: 1267766:WYH_RS00635
uniprot id: A0A0F7KKV2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

1267766:WYH RS06245
gene id: 1267766:WYH_RS06245
uniprot id: A0A0F7KT21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1267766:WYH RS01135
gene id: 1267766:WYH_RS01135
uniprot id: A0A0F7KQ79
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1267766:WYH RS12130
gene id: 1267766:WYH_RS12130
uniprot id: A0A0F7KWG6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1267766:WYH RS06425
gene id: 1267766:WYH_RS06425
uniprot id: A0A0F7KRY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1267766:WYH RS10660
gene id: 1267766:WYH_RS10660
uniprot id: A0A0F7KVE0
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS02940
gene id: 1267766:WYH_RS02940
uniprot id: A0A0F7KR39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1267766:WYH RS12250
gene id: 1267766:WYH_RS12250
uniprot id: A0A0F7KSZ2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1267766:WYH RS06050
gene id: 1267766:WYH_RS06050
uniprot id: A0A0F7KSX8
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

1267766:WYH RS10790
gene id: 1267766:WYH_RS10790
uniprot id: A0A0F7KUD5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1267766:WYH RS07730
gene id: 1267766:WYH_RS07730
uniprot id: A0A0F7KV20
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS00490
gene id: 1267766:WYH_RS00490
uniprot id: A0A0F7KPX4
names: Similarity
messages: Belongs to the AHA1 family.

1267766:WYH RS13235
gene id: 1267766:WYH_RS13235
uniprot id: A0A0F7KY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1267766:WYH RS14190
gene id: 1267766:WYH_RS14190
uniprot id: A0A0F7KYN7
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

1267766:WYH RS00485
gene id: 1267766:WYH_RS00485
uniprot id: A0A0F7KPV7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1267766:WYH RS01950
gene id: 1267766:WYH_RS01950
uniprot id: A0A0F7KQL8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1267766:WYH RS00110
gene id: 1267766:WYH_RS00110
uniprot id: A0A0F7KKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1267766:WYH RS09030
gene id: 1267766:WYH_RS09030
uniprot id: A0A0F7KUN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1267766:WYH RS08145
gene id: 1267766:WYH_RS08145
uniprot id: A0A0F7KQ81
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS11865
gene id: 1267766:WYH_RS11865
uniprot id: A0A0F7KW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1267766:WYH RS04975
gene id: 1267766:WYH_RS04975
uniprot id: A0A0F7KS10
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1267766:WYH RS10680
gene id: 1267766:WYH_RS10680
uniprot id: A0A0F7KVK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1267766:WYH RS08510
gene id: 1267766:WYH_RS08510
uniprot id: A0A0F7KT37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1267766:WYH RS16175
gene id: 1267766:WYH_RS16175
uniprot id: A0A0F7KZQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS02815
gene id: 1267766:WYH_RS02815
uniprot id: A0A0F7KS97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1267766:WYH RS00400
gene id: 1267766:WYH_RS00400
uniprot id: A0A0F7KNK4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1267766:WYH RS14135
gene id: 1267766:WYH_RS14135
uniprot id: A0A0F7KW19
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1267766:WYH RS09370
gene id: 1267766:WYH_RS09370
uniprot id: A0A0F7KR31
names: Similarity
messages: Belongs to the PrpF family.

1267766:WYH RS10730
gene id: 1267766:WYH_RS10730
uniprot id: A0A0F7KVF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS02695
gene id: 1267766:WYH_RS02695
uniprot id: A0A0F7KS72
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1267766:WYH RS13855
gene id: 1267766:WYH_RS13855
uniprot id: A0A0F7KU06
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1267766:WYH RS08095
gene id: 1267766:WYH_RS08095
uniprot id: A0A0F7KSW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1267766:WYH RS15520
gene id: 1267766:WYH_RS15520
uniprot id: A0A0F7KY72
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1267766:WYH RS07440
gene id: 1267766:WYH_RS07440
uniprot id: A0A0F7KPU7
names: Similarity
messages: Belongs to the UPF0047 family.

1267766:WYH RS03135
gene id: 1267766:WYH_RS03135
uniprot id: A0A0F7KRF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1267766:WYH RS13265
gene id: 1267766:WYH_RS13265
uniprot id: A0A0F7KX10
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1267766:WYH RS15585
gene id: 1267766:WYH_RS15585
uniprot id: A0A0F7KZC0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1267766:WYH RS06015
gene id: 1267766:WYH_RS06015
uniprot id: A0A0F7KRM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS11970
gene id: 1267766:WYH_RS11970
uniprot id: A0A0F7KV04
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS09160
gene id: 1267766:WYH_RS09160
uniprot id: A0A0F7KUI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1267766:WYH RS14670
gene id: 1267766:WYH_RS14670
uniprot id: A0A0F7KUH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS03705
gene id: 1267766:WYH_RS03705
uniprot id: A0A0F7KRQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS00395
gene id: 1267766:WYH_RS00395
uniprot id: A0A0F7KKP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1267766:WYH RS14240
gene id: 1267766:WYH_RS14240
uniprot id: A0A0F7KYP6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1267766:WYH RS06165
gene id: 1267766:WYH_RS06165
uniprot id: A0A0F7KU33
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS00500
gene id: 1267766:WYH_RS00500
uniprot id: A0A0F7KNM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1267766:WYH RS08005
gene id: 1267766:WYH_RS08005
uniprot id: A0A0F7KU27
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1267766:WYH RS03065
gene id: 1267766:WYH_RS03065
uniprot id: A0A0F7KR66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1267766:WYH RS02690
gene id: 1267766:WYH_RS02690
uniprot id: A0A0F7KPX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1267766:WYH RS00045
gene id: 1267766:WYH_RS00045
uniprot id: A0A0F7KKH4
names: Similarity
messages: Belongs to the sterol desaturase family.

1267766:WYH RS02950
gene id: 1267766:WYH_RS02950
uniprot id: A0A0F7KQ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS03370
gene id: 1267766:WYH_RS03370
uniprot id: A0A0F7KQB6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS04880
gene id: 1267766:WYH_RS04880
uniprot id: A0A0F7KNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1267766:WYH RS05880
gene id: 1267766:WYH_RS05880
uniprot id: A0A0F7KSI7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1267766:WYH RS07400
gene id: 1267766:WYH_RS07400
uniprot id: A0A0F7KUU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1267766:WYH RS08270
gene id: 1267766:WYH_RS08270
uniprot id: A0A0F7KT02
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1267766:WYH RS08435
gene id: 1267766:WYH_RS08435
uniprot id: A0A0F7KT23
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1267766:WYH RS06690
gene id: 1267766:WYH_RS06690
uniprot id: A0A0F7KTE5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1267766:WYH RS01730
gene id: 1267766:WYH_RS01730
uniprot id: A0A0F7KRP2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1267766:WYH RS04515
gene id: 1267766:WYH_RS04515
uniprot id: A0A0F7KT52
names: Similarity
messages: Belongs to the acylphosphatase family.

1267766:WYH RS10675
gene id: 1267766:WYH_RS10675
uniprot id: A0A0F7KWM7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1267766:WYH RS06755
gene id: 1267766:WYH_RS06755
uniprot id: A0A0F7KS79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1267766:WYH RS03125
gene id: 1267766:WYH_RS03125
uniprot id: A0A0F7KQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1267766:WYH RS03960
gene id: 1267766:WYH_RS03960
uniprot id: A0A0F7KRL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1267766:WYH RS07935
gene id: 1267766:WYH_RS07935
uniprot id: A0A0F7KU15
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS08580
gene id: 1267766:WYH_RS08580
uniprot id: A0A0F7KQG7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1267766:WYH RS12795
gene id: 1267766:WYH_RS12795
uniprot id: A0A0F7KVE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1267766:WYH RS00565
gene id: 1267766:WYH_RS00565
uniprot id: A0A0F7KKT6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1267766:WYH RS02760
gene id: 1267766:WYH_RS02760
uniprot id: A0A0F7KPY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1267766:WYH RS15815
gene id: 1267766:WYH_RS15815
uniprot id: A0A0F7KYA3
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1267766:WYH RS03495
gene id: 1267766:WYH_RS03495
uniprot id: A0A0F7KMH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1267766:WYH RS05325
gene id: 1267766:WYH_RS05325
uniprot id: A0A0F7KSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS08275
gene id: 1267766:WYH_RS08275
uniprot id: A0A0F7KVD8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1267766:WYH RS13660
gene id: 1267766:WYH_RS13660
uniprot id: A0A0F7KYB5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1267766:WYH RS06960
gene id: 1267766:WYH_RS06960
uniprot id: A0A0F7KTA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1267766:WYH RS03745
gene id: 1267766:WYH_RS03745
uniprot id: A0A0F7KQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS13870
gene id: 1267766:WYH_RS13870
uniprot id: A0A0F7KXA6
names: Similarity
messages: Belongs to the GcvT family.

1267766:WYH RS04680
gene id: 1267766:WYH_RS04680
uniprot id: A0A0F7KN85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1267766:WYH RS08245
gene id: 1267766:WYH_RS08245
uniprot id: A0A0F7KSZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS02165
gene id: 1267766:WYH_RS02165
uniprot id: A0A0F7KRX8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1267766:WYH RS00920
gene id: 1267766:WYH_RS00920
uniprot id: A0A0F7KR05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1267766:WYH RS12360
gene id: 1267766:WYH_RS12360
uniprot id: A0A0F7KV68
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS01790
gene id: 1267766:WYH_RS01790
uniprot id: A0A0F7KQJ8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1267766:WYH RS02805
gene id: 1267766:WYH_RS02805
uniprot id: A0A0F7KM48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1267766:WYH RS11565
gene id: 1267766:WYH_RS11565
uniprot id: A0A0F7KW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1267766:WYH RS08150
gene id: 1267766:WYH_RS08150
uniprot id: A0A0F7KSY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1267766:WYH RS02765
gene id: 1267766:WYH_RS02765
uniprot id: A0A0F7KS87
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1267766:WYH RS02245
gene id: 1267766:WYH_RS02245
uniprot id: A0A0F7KRZ2
names: Similarity
messages: Belongs to the TPP enzyme family.

1267766:WYH RS14575
gene id: 1267766:WYH_RS14575
uniprot id: A0A0F7KYU3
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS11115
gene id: 1267766:WYH_RS11115
uniprot id: A0A0F7KWW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1267766:WYH RS00160
gene id: 1267766:WYH_RS00160
uniprot id: A0A0F7KKI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1267766:WYH RS16020
gene id: 1267766:WYH_RS16020
uniprot id: A0A0F7KZJ6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1267766:WYH RS11930
gene id: 1267766:WYH_RS11930
uniprot id: A0A0F7KXD8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1267766:WYH RS05545
gene id: 1267766:WYH_RS05545
uniprot id: A0A0F7KTP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS12945
gene id: 1267766:WYH_RS12945
uniprot id: A0A0F7KXX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1267766:WYH RS14160
gene id: 1267766:WYH_RS14160
uniprot id: A0A0F7KW23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1267766:WYH RS06950
gene id: 1267766:WYH_RS06950
uniprot id: A0A0F7KUJ9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS08825
gene id: 1267766:WYH_RS08825
uniprot id: A0A0F7KUG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS13225
gene id: 1267766:WYH_RS13225
uniprot id: A0A0F7KTI3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1267766:WYH RS11765
gene id: 1267766:WYH_RS11765
uniprot id: A0A0F7KSN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1267766:WYH RS12980
gene id: 1267766:WYH_RS12980
uniprot id: A0A0F7KWS3
names: Similarity
messages: Belongs to the TPP enzyme family.

1267766:WYH RS14410
gene id: 1267766:WYH_RS14410
uniprot id: A0A0F7KW69
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1267766:WYH RS10650
gene id: 1267766:WYH_RS10650
uniprot id: A0A0F7KWM2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1267766:WYH RS00730
gene id: 1267766:WYH_RS00730
uniprot id: A0A0F7KQ14
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1267766:WYH RS14875
gene id: 1267766:WYH_RS14875
uniprot id: A0A0F7KUL3
names: Similarity
messages: Belongs to the LOG family.

1267766:WYH RS01190
gene id: 1267766:WYH_RS01190
uniprot id: A0A0F7KL70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1267766:WYH RS12835
gene id: 1267766:WYH_RS12835
uniprot id: A0A0F7KWP3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS11155
gene id: 1267766:WYH_RS11155
uniprot id: A0A0F7KS69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1267766:WYH RS12810
gene id: 1267766:WYH_RS12810
uniprot id: A0A0F7KWN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS07675
gene id: 1267766:WYH_RS07675
uniprot id: A0A0F7KTW5
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS05790
gene id: 1267766:WYH_RS05790
uniprot id: A0A0F7KTU6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1267766:WYH RS13690
gene id: 1267766:WYH_RS13690
uniprot id: A0A0F7KX80
names: Similarity
messages: Belongs to the UPF0311 family.

1267766:WYH RS00420
gene id: 1267766:WYH_RS00420
uniprot id: A0A0F7KKP8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1267766:WYH RS09260
gene id: 1267766:WYH_RS09260
uniprot id: A0A0F7KUK1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1267766:WYH RS00655
gene id: 1267766:WYH_RS00655
uniprot id: A0A0F7KQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1267766:WYH RS09020
gene id: 1267766:WYH_RS09020
uniprot id: A0A0F7KTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS01980
gene id: 1267766:WYH_RS01980
uniprot id: A0A0F7KLQ8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1267766:WYH RS09810
gene id: 1267766:WYH_RS09810
uniprot id: A0A0F7KW67
names: Similarity
messages: Belongs to the virb1 family.

1267766:WYH RS04660
gene id: 1267766:WYH_RS04660
uniprot id: A0A0F7KQZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1267766:WYH RS13780
gene id: 1267766:WYH_RS13780
uniprot id: A0A0F7KVT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1267766:WYH RS10520
gene id: 1267766:WYH_RS10520
uniprot id: A0A0F7KWK6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS08110
gene id: 1267766:WYH_RS08110
uniprot id: A0A0F7KU42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1267766:WYH RS13640
gene id: 1267766:WYH_RS13640
uniprot id: A0A0F7KX71
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1267766:WYH RS04990
gene id: 1267766:WYH_RS04990
uniprot id: A0A0F7KTD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS15100
gene id: 1267766:WYH_RS15100
uniprot id: A0A0F7KXY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1267766:WYH RS01095
gene id: 1267766:WYH_RS01095
uniprot id: A0A0F7KNX8
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS11900
gene id: 1267766:WYH_RS11900
uniprot id: A0A0F7KUZ0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1267766:WYH RS11805
gene id: 1267766:WYH_RS11805
uniprot id: A0A0F7KXC3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1267766:WYH RS13770
gene id: 1267766:WYH_RS13770
uniprot id: A0A0F7KX74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1267766:WYH RS15560
gene id: 1267766:WYH_RS15560
uniprot id: A0A0F7KZB4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1267766:WYH RS11840
gene id: 1267766:WYH_RS11840
uniprot id: A0A0F7KW68
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1267766:WYH RS12710
gene id: 1267766:WYH_RS12710
uniprot id: A0A0F7KWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1267766:WYH RS10290
gene id: 1267766:WYH_RS10290
uniprot id: A0A0F7KV66
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1267766:WYH RS08000
gene id: 1267766:WYH_RS08000
uniprot id: A0A0F7KV80
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1267766:WYH RS15095
gene id: 1267766:WYH_RS15095
uniprot id: A0A0F7KXW2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1267766:WYH RS06510
gene id: 1267766:WYH_RS06510
uniprot id: A0A0F7KT78
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1267766:WYH RS03305
gene id: 1267766:WYH_RS03305
uniprot id: A0A0F7KSI4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1267766:WYH RS10400
gene id: 1267766:WYH_RS10400
uniprot id: A0A0F7KVE7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1267766:WYH RS00480
gene id: 1267766:WYH_RS00480
uniprot id: A0A0F7KQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1267766:WYH RS02015
gene id: 1267766:WYH_RS02015
uniprot id: A0A0F7KRU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1267766:WYH RS06805
gene id: 1267766:WYH_RS06805
uniprot id: A0A0F7KUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1267766:WYH RS00315
gene id: 1267766:WYH_RS00315
uniprot id: A0A0F7KPU6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1267766:WYH RS03110
gene id: 1267766:WYH_RS03110
uniprot id: A0A0F7KRE5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1267766:WYH RS07185
gene id: 1267766:WYH_RS07185
uniprot id: A0A0F7KPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1267766:WYH RS01970
gene id: 1267766:WYH_RS01970
uniprot id: A0A0F7KQT7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1267766:WYH RS04050
gene id: 1267766:WYH_RS04050
uniprot id: A0A0F7KRZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1267766:WYH RS10230
gene id: 1267766:WYH_RS10230
uniprot id: A0A0F7KWF4
names: Function
messages: Acts on leucine, isoleucine and valine.

1267766:WYH RS04635
gene id: 1267766:WYH_RS04635
uniprot id: A0A0F7KQZ0
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS02200
gene id: 1267766:WYH_RS02200
uniprot id: A0A0F7KQY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1267766:WYH RS01785
gene id: 1267766:WYH_RS01785
uniprot id: A0A0F7KQR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1267766:WYH RS10045
gene id: 1267766:WYH_RS10045
uniprot id: A0A0F7KRI1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1267766:WYH RS13250
gene id: 1267766:WYH_RS13250
uniprot id: A0A0F7KTI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

1267766:WYH RS08940
gene id: 1267766:WYH_RS08940
uniprot id: A0A0F7KTC4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1267766:WYH RS09635
gene id: 1267766:WYH_RS09635
uniprot id: A0A0F7KUY9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS00340
gene id: 1267766:WYH_RS00340
uniprot id: A0A0F7KPV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1267766:WYH RS06980
gene id: 1267766:WYH_RS06980
uniprot id: A0A0F7KTJ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1267766:WYH RS00015
gene id: 1267766:WYH_RS00015
uniprot id: A0A0F7KZJ8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1267766:WYH RS13625
gene id: 1267766:WYH_RS13625
uniprot id: A0A0F7KTR8
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1267766:WYH RS15460
gene id: 1267766:WYH_RS15460
uniprot id: A0A0F7KZ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1267766:WYH RS07305
gene id: 1267766:WYH_RS07305
uniprot id: A0A0F7KTG0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1267766:WYH RS10695
gene id: 1267766:WYH_RS10695
uniprot id: A0A0F7KWN2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1267766:WYH RS09460
gene id: 1267766:WYH_RS09460
uniprot id: A0A0F7KUV6
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

1267766:WYH RS07850
gene id: 1267766:WYH_RS07850
uniprot id: A0A0F7KV50
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1267766:WYH RS00130
gene id: 1267766:WYH_RS00130
uniprot id: A0A0F7KPR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1267766:WYH RS06325
gene id: 1267766:WYH_RS06325
uniprot id: A0A0F7KRV1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS03900
gene id: 1267766:WYH_RS03900
uniprot id: A0A0F7KRV2
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1267766:WYH RS01635
gene id: 1267766:WYH_RS01635
uniprot id: A0A0F7KQH9
names: Similarity
messages: Belongs to the tannase family.

1267766:WYH RS03215
gene id: 1267766:WYH_RS03215
uniprot id: A0A0F7KR92
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1267766:WYH RS13420
gene id: 1267766:WYH_RS13420
uniprot id: A0A0F7KTM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1267766:WYH RS05745
gene id: 1267766:WYH_RS05745
uniprot id: A0A0F7KSU6
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS04840
gene id: 1267766:WYH_RS04840
uniprot id: A0A0F7KTA7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1267766:WYH RS12210
gene id: 1267766:WYH_RS12210
uniprot id: A0A0F7KV43
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1267766:WYH RS07960
gene id: 1267766:WYH_RS07960
uniprot id: A0A0F7KU19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1267766:WYH RS02455
gene id: 1267766:WYH_RS02455
uniprot id: A0A0F7KQU8
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS01975
gene id: 1267766:WYH_RS01975
uniprot id: A0A0F7KQM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1267766:WYH RS11275
gene id: 1267766:WYH_RS11275
uniprot id: A0A0F7KS95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1267766:WYH RS08795
gene id: 1267766:WYH_RS08795
uniprot id: A0A0F7KT95
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1267766:WYH RS04040
gene id: 1267766:WYH_RS04040
uniprot id: A0A0F7KMV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS12180
gene id: 1267766:WYH_RS12180
uniprot id: A0A0F7KWG8
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1267766:WYH RS01750
gene id: 1267766:WYH_RS01750
uniprot id: A0A0F7KPD2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1267766:WYH RS14565
gene id: 1267766:WYH_RS14565
uniprot id: A0A0F7KUG7
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS00135
gene id: 1267766:WYH_RS00135
uniprot id: A0A0F7KKI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1267766:WYH RS03950
gene id: 1267766:WYH_RS03950
uniprot id: A0A0F7KSX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS01065
gene id: 1267766:WYH_RS01065
uniprot id: A0A0F7KL47
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

1267766:WYH RS05510
gene id: 1267766:WYH_RS05510
uniprot id: A0A0F7KNS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1267766:WYH RS13545
gene id: 1267766:WYH_RS13545
uniprot id: A0A0F7KTQ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1267766:WYH RS14945
gene id: 1267766:WYH_RS14945
uniprot id: A0A0F7KXV7
names: Similarity
messages: Belongs to the UPF0178 family.

1267766:WYH RS07215
gene id: 1267766:WYH_RS07215
uniprot id: A0A0F7KSF8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1267766:WYH RS03945
gene id: 1267766:WYH_RS03945
uniprot id: A0A0F7KQJ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1267766:WYH RS00825
gene id: 1267766:WYH_RS00825
uniprot id: A0A0F7KQ31
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS01055
gene id: 1267766:WYH_RS01055
uniprot id: A0A0F7KQ75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1267766:WYH RS01525
gene id: 1267766:WYH_RS01525
uniprot id: A0A0F7KQL5
names: Similarity
messages: Belongs to the tannase family.

1267766:WYH RS07560
gene id: 1267766:WYH_RS07560
uniprot id: A0A0F7KPW7
names: Similarity
messages: Belongs to the ArsC family.

1267766:WYH RS00355
gene id: 1267766:WYH_RS00355
uniprot id: A0A0F7KQP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1267766:WYH RS13675
gene id: 1267766:WYH_RS13675
uniprot id: A0A0F7KTV6
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1267766:WYH RS01350
gene id: 1267766:WYH_RS01350
uniprot id: A0A0F7KQB7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1267766:WYH RS12580
gene id: 1267766:WYH_RS12580
uniprot id: A0A0F7KVA7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1267766:WYH RS00930
gene id: 1267766:WYH_RS00930
uniprot id: A0A0F7KQ46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1267766:WYH RS09870
gene id: 1267766:WYH_RS09870
uniprot id: A0A0F7KUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1267766:WYH RS00560
gene id: 1267766:WYH_RS00560
uniprot id: A0A0F7KPY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1267766:WYH RS15450
gene id: 1267766:WYH_RS15450
uniprot id: A0A0F7KUW6
names: Similarity
messages: Belongs to the type III secretion exporter family.

1267766:WYH RS12330
gene id: 1267766:WYH_RS12330
uniprot id: A0A0F7KT14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1267766:WYH RS04350
gene id: 1267766:WYH_RS04350
uniprot id: A0A0F7KQU0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1267766:WYH RS09950
gene id: 1267766:WYH_RS09950
uniprot id: A0A0F7KU01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1267766:WYH RS10120
gene id: 1267766:WYH_RS10120
uniprot id: A0A0F7KRJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS06070
gene id: 1267766:WYH_RS06070
uniprot id: A0A0F7KSY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1267766:WYH RS04630
gene id: 1267766:WYH_RS04630
uniprot id: A0A0F7KN77
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS00770
gene id: 1267766:WYH_RS00770
uniprot id: A0A0F7KQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1267766:WYH RS03725
gene id: 1267766:WYH_RS03725
uniprot id: A0A0F7KSS6
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1267766:WYH RS08160
gene id: 1267766:WYH_RS08160
uniprot id: A0A0F7KU51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS01050
gene id: 1267766:WYH_RS01050
uniprot id: A0A0F7KR40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1267766:WYH RS02195
gene id: 1267766:WYH_RS02195
uniprot id: A0A0F7KRY3
names: Similarity
messages: Belongs to the CapA family.

1267766:WYH RS04775
gene id: 1267766:WYH_RS04775
uniprot id: A0A0F7KRY1
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1267766:WYH RS02795
gene id: 1267766:WYH_RS02795
uniprot id: A0A0F7KR94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1267766:WYH RS08890
gene id: 1267766:WYH_RS08890
uniprot id: A0A0F7KTB5
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS04905
gene id: 1267766:WYH_RS04905
uniprot id: A0A0F7KNF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS03755
gene id: 1267766:WYH_RS03755
uniprot id: A0A0F7KRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1267766:WYH RS10470
gene id: 1267766:WYH_RS10470
uniprot id: A0A0F7KWJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1267766:WYH RS06585
gene id: 1267766:WYH_RS06585
uniprot id: A0A0F7KUD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1267766:WYH RS06625
gene id: 1267766:WYH_RS06625
uniprot id: A0A0F7KPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1267766:WYH RS04090
gene id: 1267766:WYH_RS04090
uniprot id: A0A0F7KMW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1267766:WYH RS02355
gene id: 1267766:WYH_RS02355
uniprot id: A0A0F7KQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1267766:WYH RS10755
gene id: 1267766:WYH_RS10755
uniprot id: A0A0F7KVG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1267766:WYH RS02010
gene id: 1267766:WYH_RS02010
uniprot id: A0A0F7KPH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1267766:WYH RS15510
gene id: 1267766:WYH_RS15510
uniprot id: A0A0F7KZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1267766:WYH RS02035
gene id: 1267766:WYH_RS02035
uniprot id: A0A0F7KPI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS05515
gene id: 1267766:WYH_RS05515
uniprot id: A0A0F7KRE3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS00260
gene id: 1267766:WYH_RS00260
uniprot id: A0A0F7KPR3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1267766:WYH RS11585
gene id: 1267766:WYH_RS11585
uniprot id: A0A0F7KX85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS13735
gene id: 1267766:WYH_RS13735
uniprot id: A0A0F7KYD0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1267766:WYH RS06065
gene id: 1267766:WYH_RS06065
uniprot id: A0A0F7KU10
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1267766:WYH RS15395
gene id: 1267766:WYH_RS15395
uniprot id: A0A0F7KWU3
names: Similarity
messages: Belongs to the pirin family.

1267766:WYH RS02320
gene id: 1267766:WYH_RS02320
uniprot id: A0A0F7KS05
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1267766:WYH RS13000
gene id: 1267766:WYH_RS13000
uniprot id: A0A0F7KWV5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1267766:WYH RS11545
gene id: 1267766:WYH_RS11545
uniprot id: A0A0F7KW22
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1267766:WYH RS06750
gene id: 1267766:WYH_RS06750
uniprot id: A0A0F7KPK0
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1267766:WYH RS06855
gene id: 1267766:WYH_RS06855
uniprot id: A0A0F7KUI2
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1267766:WYH RS14685
gene id: 1267766:WYH_RS14685
uniprot id: A0A0F7KXN6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1267766:WYH RS15150
gene id: 1267766:WYH_RS15150
uniprot id: A0A0F7KXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1267766:WYH RS12865
gene id: 1267766:WYH_RS12865
uniprot id: A0A0F7KTB4
names: Similarity
messages: Belongs to the AAA ATPase family.

1267766:WYH RS15405
gene id: 1267766:WYH_RS15405
uniprot id: A0A0F7KY20
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

1267766:WYH RS13180
gene id: 1267766:WYH_RS13180
uniprot id: A0A0F7KVL0
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS13095
gene id: 1267766:WYH_RS13095
uniprot id: A0A0F7KVJ7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1267766:WYH RS10860
gene id: 1267766:WYH_RS10860
uniprot id: A0A0F7KUE8
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1267766:WYH RS12020
gene id: 1267766:WYH_RS12020
uniprot id: A0A0F7KV13
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

1267766:WYH RS06440
gene id: 1267766:WYH_RS06440
uniprot id: A0A0F7KSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1267766:WYH RS12845
gene id: 1267766:WYH_RS12845
uniprot id: A0A0F7KVF4
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS03405
gene id: 1267766:WYH_RS03405
uniprot id: A0A0F7KRJ6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1267766:WYH RS12960
gene id: 1267766:WYH_RS12960
uniprot id: A0A0F7KTD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS16185
gene id: 1267766:WYH_RS16185
uniprot id: A0A0F7KYL3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1267766:WYH RS03650
gene id: 1267766:WYH_RS03650
uniprot id: A0A0F7KSR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1267766:WYH RS02070
gene id: 1267766:WYH_RS02070
uniprot id: A0A0F7KQV4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1267766:WYH RS08525
gene id: 1267766:WYH_RS08525
uniprot id: A0A0F7KU20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1267766:WYH RS06330
gene id: 1267766:WYH_RS06330
uniprot id: A0A0F7KU66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1267766:WYH RS10645
gene id: 1267766:WYH_RS10645
uniprot id: A0A0F7KUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS02180
gene id: 1267766:WYH_RS02180
uniprot id: A0A0F7KQQ4
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS14655
gene id: 1267766:WYH_RS14655
uniprot id: A0A0F7KYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS10315
gene id: 1267766:WYH_RS10315
uniprot id: A0A0F7KV73
names: Similarity
messages: Belongs to the peptidase M13 family.

1267766:WYH RS08125
gene id: 1267766:WYH_RS08125
uniprot id: A0A0F7KSY0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1267766:WYH RS00185
gene id: 1267766:WYH_RS00185
uniprot id: A0A0F7KKJ0
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS00695
gene id: 1267766:WYH_RS00695
uniprot id: A0A0F7KQW0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1267766:WYH RS16300
gene id: 1267766:WYH_RS16300
uniprot id: A0A0F7KYM8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1267766:WYH RS11285
gene id: 1267766:WYH_RS11285
uniprot id: A0A0F7KX03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1267766:WYH RS09930
gene id: 1267766:WYH_RS09930
uniprot id: A0A0F7KTZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1267766:WYH RS12305
gene id: 1267766:WYH_RS12305
uniprot id: A0A0F7KT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1267766:WYH RS03985
gene id: 1267766:WYH_RS03985
uniprot id: A0A0F7KRM1
names: Subcellular Location Annotation
messages: Nucleus

1267766:WYH RS00630
gene id: 1267766:WYH_RS00630
uniprot id: A0A0F7KPZ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1267766:WYH RS11535
gene id: 1267766:WYH_RS11535
uniprot id: A0A0F7KX77
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1267766:WYH RS11605
gene id: 1267766:WYH_RS11605
uniprot id: A0A0F7KUT9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS12820
gene id: 1267766:WYH_RS12820
uniprot id: A0A0F7KVE9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1267766:WYH RS15530
gene id: 1267766:WYH_RS15530
uniprot id: A0A0F7KWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1267766:WYH RS08775
gene id: 1267766:WYH_RS08775
uniprot id: A0A0F7KVL9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS07815
gene id: 1267766:WYH_RS07815
uniprot id: A0A0F7KQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1267766:WYH RS13240
gene id: 1267766:WYH_RS13240
uniprot id: A0A0F7KX05
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1267766:WYH RS14355
gene id: 1267766:WYH_RS14355
uniprot id: A0A0F7KUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS08535
gene id: 1267766:WYH_RS08535
uniprot id: A0A0F7KT42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS07465
gene id: 1267766:WYH_RS07465
uniprot id: A0A0F7KPV1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1267766:WYH RS01220
gene id: 1267766:WYH_RS01220
uniprot id: A0A0F7KR80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1267766:WYH RS10840
gene id: 1267766:WYH_RS10840
uniprot id: A0A0F7KUE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1267766:WYH RS15125
gene id: 1267766:WYH_RS15125
uniprot id: A0A0F7KXZ3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1267766:WYH RS03560
gene id: 1267766:WYH_RS03560
uniprot id: A0A0F7KRM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1267766:WYH RS01860
gene id: 1267766:WYH_RS01860
uniprot id: A0A0F7KQS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1267766:WYH RS15765
gene id: 1267766:WYH_RS15765
uniprot id: A0A0F7KY93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1267766:WYH RS10495
gene id: 1267766:WYH_RS10495
uniprot id: A0A0F7KWK2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1267766:WYH RS09050
gene id: 1267766:WYH_RS09050
uniprot id: A0A0F7KVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1267766:WYH RS13805
gene id: 1267766:WYH_RS13805
uniprot id: A0A0F7KYE6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1267766:WYH RS13305
gene id: 1267766:WYH_RS13305
uniprot id: A0A0F7KTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1267766:WYH RS15610
gene id: 1267766:WYH_RS15610
uniprot id: A0A0F7KZC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1267766:WYH RS02955
gene id: 1267766:WYH_RS02955
uniprot id: A0A0F7KSC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1267766:WYH RS00445
gene id: 1267766:WYH_RS00445
uniprot id: A0A0F7KKQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1267766:WYH RS11085
gene id: 1267766:WYH_RS11085
uniprot id: A0A0F7KS53
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1267766:WYH RS02540
gene id: 1267766:WYH_RS02540
uniprot id: A0A0F7KPU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1267766:WYH RS09645
gene id: 1267766:WYH_RS09645
uniprot id: A0A0F7KRA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1267766:WYH RS03140
gene id: 1267766:WYH_RS03140
uniprot id: A0A0F7KR82
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1267766:WYH RS07000
gene id: 1267766:WYH_RS07000
uniprot id: A0A0F7KTJ8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1267766:WYH RS10690
gene id: 1267766:WYH_RS10690
uniprot id: A0A0F7KRX5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1267766:WYH RS08835
gene id: 1267766:WYH_RS08835
uniprot id: A0A0F7KQM2
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS08085
gene id: 1267766:WYH_RS08085
uniprot id: A0A0F7KTV7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1267766:WYH RS05925
gene id: 1267766:WYH_RS05925
uniprot id: A0A0F7KSX1
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1267766:WYH RS02350
gene id: 1267766:WYH_RS02350
uniprot id: A0A0F7KR10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1267766:WYH RS14055
gene id: 1267766:WYH_RS14055
uniprot id: A0A0F7KU88
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1267766:WYH RS06615
gene id: 1267766:WYH_RS06615
uniprot id: A0A0F7KTD0
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS12435
gene id: 1267766:WYH_RS12435
uniprot id: A0A0F7KWK5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1267766:WYH RS03320
gene id: 1267766:WYH_RS03320
uniprot id: A0A0F7KMD4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS10375
gene id: 1267766:WYH_RS10375
uniprot id: A0A0F7KWI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1267766:WYH RS09665
gene id: 1267766:WYH_RS09665
uniprot id: A0A0F7KUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1267766:WYH RS04325
gene id: 1267766:WYH_RS04325
uniprot id: A0A0F7KT22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1267766:WYH RS09055
gene id: 1267766:WYH_RS09055
uniprot id: A0A0F7KUP8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS15930
gene id: 1267766:WYH_RS15930
uniprot id: A0A0F7KYE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1267766:WYH RS01080
gene id: 1267766:WYH_RS01080
uniprot id: A0A0F7KQ80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1267766:WYH RS08180
gene id: 1267766:WYH_RS08180
uniprot id: A0A0F7KVB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1267766:WYH RS06940
gene id: 1267766:WYH_RS06940
uniprot id: A0A0F7KPM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1267766:WYH RS01100
gene id: 1267766:WYH_RS01100
uniprot id: A0A0F7KR53
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS00945
gene id: 1267766:WYH_RS00945
uniprot id: A0A0F7KR11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS10175
gene id: 1267766:WYH_RS10175
uniprot id: A0A0F7KU36
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1267766:WYH RS01920
gene id: 1267766:WYH_RS01920
uniprot id: A0A0F7KQS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS15550
gene id: 1267766:WYH_RS15550
uniprot id: A0A0F7KUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1267766:WYH RS15165
gene id: 1267766:WYH_RS15165
uniprot id: A0A0F7KZ33
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1267766:WYH RS07840
gene id: 1267766:WYH_RS07840
uniprot id: A0A0F7KQ20
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1267766:WYH RS02450
gene id: 1267766:WYH_RS02450
uniprot id: A0A0F7KR32
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1267766:WYH RS06910
gene id: 1267766:WYH_RS06910
uniprot id: A0A0F7KT96
names: Similarity
messages: Belongs to the bacterial secretin family.

1267766:WYH RS06775
gene id: 1267766:WYH_RS06775
uniprot id: A0A0F7KS85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1267766:WYH RS12290
gene id: 1267766:WYH_RS12290
uniprot id: A0A0F7KXJ5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS06850
gene id: 1267766:WYH_RS06850
uniprot id: A0A0F7KS99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1267766:WYH RS04470
gene id: 1267766:WYH_RS04470
uniprot id: A0A0F7KS59
names: Similarity
messages: Belongs to the cytochrome P450 family.

1267766:WYH RS01265
gene id: 1267766:WYH_RS01265
uniprot id: A0A0F7KRB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1267766:WYH RS14300
gene id: 1267766:WYH_RS14300
uniprot id: A0A0F7KXK3
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1267766:WYH RS00545
gene id: 1267766:WYH_RS00545
uniprot id: A0A0F7KKT0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1267766:WYH RS12225
gene id: 1267766:WYH_RS12225
uniprot id: A0A0F7KWE1
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS11540
gene id: 1267766:WYH_RS11540
uniprot id: A0A0F7KW52
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1267766:WYH RS11910
gene id: 1267766:WYH_RS11910
uniprot id: A0A0F7KWC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1267766:WYH RS02440
gene id: 1267766:WYH_RS02440
uniprot id: A0A0F7KPS7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1267766:WYH RS02580
gene id: 1267766:WYH_RS02580
uniprot id: A0A0F7KQW9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1267766:WYH RS12885
gene id: 1267766:WYH_RS12885
uniprot id: A0A0F7KWQ3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1267766:WYH RS04695
gene id: 1267766:WYH_RS04695
uniprot id: A0A0F7KSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1267766:WYH RS02620
gene id: 1267766:WYH_RS02620
uniprot id: A0A0F7KS57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1267766:WYH RS02935
gene id: 1267766:WYH_RS02935
uniprot id: A0A0F7KRA9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS15690
gene id: 1267766:WYH_RS15690
uniprot id: A0A0F7KY78
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS11340
gene id: 1267766:WYH_RS11340
uniprot id: A0A0F7KVY4
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1267766:WYH RS01410
gene id: 1267766:WYH_RS01410
uniprot id: A0A0F7KP38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1267766:WYH RS15445
gene id: 1267766:WYH_RS15445
uniprot id: A0A0F7KY57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1267766:WYH RS15580
gene id: 1267766:WYH_RS15580
uniprot id: A0A0F7KWX9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1267766:WYH RS00595
gene id: 1267766:WYH_RS00595
uniprot id: A0A0F7KNP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1267766:WYH RS15265
gene id: 1267766:WYH_RS15265
uniprot id: A0A0F7KUT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS09075
gene id: 1267766:WYH_RS09075
uniprot id: A0A0F7KVU9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1267766:WYH RS01255
gene id: 1267766:WYH_RS01255
uniprot id: A0A0F7KQA0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS09670
gene id: 1267766:WYH_RS09670
uniprot id: A0A0F7KRB2
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1267766:WYH RS07670
gene id: 1267766:WYH_RS07670
uniprot id: A0A0F7KV07
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1267766:WYH RS01870
gene id: 1267766:WYH_RS01870
uniprot id: A0A0F7KLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS09650
gene id: 1267766:WYH_RS09650
uniprot id: A0A0F7KTU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1267766:WYH RS01140
gene id: 1267766:WYH_RS01140
uniprot id: A0A0F7KL61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1267766:WYH RS15360
gene id: 1267766:WYH_RS15360
uniprot id: A0A0F7KY38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS02790
gene id: 1267766:WYH_RS02790
uniprot id: A0A0F7KS93
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1267766:WYH RS15485
gene id: 1267766:WYH_RS15485
uniprot id: A0A0F7KZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1267766:WYH RS16335
gene id: 1267766:WYH_RS16335
uniprot id: A0A0F7KXF6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1267766:WYH RS15335
gene id: 1267766:WYH_RS15335
uniprot id: A0A0F7KY33
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1267766:WYH RS06700
gene id: 1267766:WYH_RS06700
uniprot id: A0A0F7KPI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1267766:WYH RS01775
gene id: 1267766:WYH_RS01775
uniprot id: A0A0F7KPD6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS10105
gene id: 1267766:WYH_RS10105
uniprot id: A0A0F7KWC8
names: Subcellular Location Annotation
messages: Mitochondrion

1267766:WYH RS01155
gene id: 1267766:WYH_RS01155
uniprot id: A0A0F7KQ97
names: Similarity
messages: Belongs to the peptidase S66 family.

1267766:WYH RS11485
gene id: 1267766:WYH_RS11485
uniprot id: A0A0F7KX66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1267766:WYH RS11560
gene id: 1267766:WYH_RS11560
uniprot id: A0A0F7KX81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1267766:WYH RS11385
gene id: 1267766:WYH_RS11385
uniprot id: A0A0F7KX22
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1267766:WYH RS11415
gene id: 1267766:WYH_RS11415
uniprot id: A0A0F7KVZ4
names: Similarity
messages: Belongs to the UPF0235 family.

1267766:WYH RS13480
gene id: 1267766:WYH_RS13480
uniprot id: A0A0F7KY82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1267766:WYH RS15780
gene id: 1267766:WYH_RS15780
uniprot id: A0A0F7KX17
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1267766:WYH RS11965
gene id: 1267766:WYH_RS11965
uniprot id: A0A0F7KSS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1267766:WYH RS02435
gene id: 1267766:WYH_RS02435
uniprot id: A0A0F7KLY7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1267766:WYH RS12430
gene id: 1267766:WYH_RS12430
uniprot id: A0A0F7KXM0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1267766:WYH RS13960
gene id: 1267766:WYH_RS13960
uniprot id: A0A0F7KVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1267766:WYH RS04100
gene id: 1267766:WYH_RS04100
uniprot id: A0A0F7KT00
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS02000
gene id: 1267766:WYH_RS02000
uniprot id: A0A0F7KQM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS10850
gene id: 1267766:WYH_RS10850
uniprot id: A0A0F7KVQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1267766:WYH RS07610
gene id: 1267766:WYH_RS07610
uniprot id: A0A0F7KPX5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1267766:WYH RS09250
gene id: 1267766:WYH_RS09250
uniprot id: A0A0F7KVX8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1267766:WYH RS15605
gene id: 1267766:WYH_RS15605
uniprot id: A0A0F7KWY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. In Gram-negative bacteria, at least four rings, L, P, S and M are present, whereas Gram-positive bacteria lack the L and P rings. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF build up the proximal portion of the rod with about 6 subunits each. Rod assembly occurs by export via the flagellum-specific pathway of its constituent proteins and by their incorporation into the rod structure in the probable order of FlgB, FlgC, FlgF and FlgG. Another protein, FliE, also assembles onto the stable rod structure.

1267766:WYH RS07085
gene id: 1267766:WYH_RS07085
uniprot id: A0A0F7KPN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS11095
gene id: 1267766:WYH_RS11095
uniprot id: A0A0F7KWW2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1267766:WYH RS11880
gene id: 1267766:WYH_RS11880
uniprot id: A0A0F7KXD1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1267766:WYH RS00735
gene id: 1267766:WYH_RS00735
uniprot id: A0A0F7KKX5
names: Similarity
messages: Belongs to the virb1 family.

1267766:WYH RS10140
gene id: 1267766:WYH_RS10140
uniprot id: A0A0F7KV34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1267766:WYH RS10435
gene id: 1267766:WYH_RS10435
uniprot id: A0A0F7KRR1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1267766:WYH RS01840
gene id: 1267766:WYH_RS01840
uniprot id: A0A0F7KQR8
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS15755
gene id: 1267766:WYH_RS15755
uniprot id: A0A0F7KX12
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1267766:WYH RS13025
gene id: 1267766:WYH_RS13025
uniprot id: A0A0F7KWW0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1267766:WYH RS05960
gene id: 1267766:WYH_RS05960
uniprot id: A0A0F7KP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS08815
gene id: 1267766:WYH_RS08815
uniprot id: A0A0F7KQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1267766:WYH RS06010
gene id: 1267766:WYH_RS06010
uniprot id: A0A0F7KP21
names: Similarity
messages: Belongs to the ros/MucR family.

1267766:WYH RS01165
gene id: 1267766:WYH_RS01165
uniprot id: A0A0F7KL67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1267766:WYH RS14860
gene id: 1267766:WYH_RS14860
uniprot id: A0A0F7KYY6
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS00430
gene id: 1267766:WYH_RS00430
uniprot id: A0A0F7KQR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1267766:WYH RS10555
gene id: 1267766:WYH_RS10555
uniprot id: A0A0F7KVH8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1267766:WYH RS16150
gene id: 1267766:WYH_RS16150
uniprot id: A0A0F7KZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS12365
gene id: 1267766:WYH_RS12365
uniprot id: A0A0F7KXK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1267766:WYH RS07050
gene id: 1267766:WYH_RS07050
uniprot id: A0A0F7KTK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

1267766:WYH RS03995
gene id: 1267766:WYH_RS03995
uniprot id: A0A0F7KQK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS05195
gene id: 1267766:WYH_RS05195
uniprot id: A0A0F7KR71
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1267766:WYH RS06530
gene id: 1267766:WYH_RS06530
uniprot id: A0A0F7KUD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1267766:WYH RS06590
gene id: 1267766:WYH_RS06590
uniprot id: A0A0F7KTC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1267766:WYH RS14415
gene id: 1267766:WYH_RS14415
uniprot id: A0A0F7KYR6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1267766:WYH RS01810
gene id: 1267766:WYH_RS01810
uniprot id: A0A0F7KRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1267766:WYH RS00555
gene id: 1267766:WYH_RS00555
uniprot id: A0A0F7KQT4
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1267766:WYH RS07065
gene id: 1267766:WYH_RS07065
uniprot id: A0A0F7KSD4
names: Function
messages: Multidrug efflux pump.

1267766:WYH RS00190
gene id: 1267766:WYH_RS00190
uniprot id: A0A0F7KNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS12985
gene id: 1267766:WYH_RS12985
uniprot id: A0A0F7KTD9
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1267766:WYH RS05980
gene id: 1267766:WYH_RS05980
uniprot id: A0A0F7KSK9
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1267766:WYH RS06990
gene id: 1267766:WYH_RS06990
uniprot id: A0A0F7KSC3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1267766:WYH RS00880
gene id: 1267766:WYH_RS00880
uniprot id: A0A0F7KQ39
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1267766:WYH RS12610
gene id: 1267766:WYH_RS12610
uniprot id: A0A0F7KXQ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1267766:WYH RS04245
gene id: 1267766:WYH_RS04245
uniprot id: A0A0F7KQS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1267766:WYH RS03335
gene id: 1267766:WYH_RS03335
uniprot id: A0A0F7KRI2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1267766:WYH RS15555
gene id: 1267766:WYH_RS15555
uniprot id: A0A0F7KWX5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1267766:WYH RS16180
gene id: 1267766:WYH_RS16180
uniprot id: A0A0F7KYK6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1267766:WYH RS13635
gene id: 1267766:WYH_RS13635
uniprot id: A0A0F7KYB0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1267766:WYH RS02745
gene id: 1267766:WYH_RS02745
uniprot id: A0A0F7KR88
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS00685
gene id: 1267766:WYH_RS00685
uniprot id: A0A0F7KKW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1267766:WYH RS14195
gene id: 1267766:WYH_RS14195
uniprot id: A0A0F7KXH1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1267766:WYH RS04125
gene id: 1267766:WYH_RS04125
uniprot id: A0A0F7KT01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1267766:WYH RS13745
gene id: 1267766:WYH_RS13745
uniprot id: A0A0F7KX72
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1267766:WYH RS05800
gene id: 1267766:WYH_RS05800
uniprot id: A0A0F7KSH2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1267766:WYH RS08065
gene id: 1267766:WYH_RS08065
uniprot id: A0A0F7KQ67
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1267766:WYH RS01930
gene id: 1267766:WYH_RS01930
uniprot id: A0A0F7KLP8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS02630
gene id: 1267766:WYH_RS02630
uniprot id: A0A0F7KQX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1267766:WYH RS13435
gene id: 1267766:WYH_RS13435
uniprot id: A0A0F7KX43
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1267766:WYH RS09710
gene id: 1267766:WYH_RS09710
uniprot id: A0A0F7KV05
names: Similarity
messages: Belongs to the GSP E family.

1267766:WYH RS06265
gene id: 1267766:WYH_RS06265
uniprot id: A0A0F7KU50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1267766:WYH RS04130
gene id: 1267766:WYH_RS04130
uniprot id: A0A0F7KS07
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1267766:WYH RS00235
gene id: 1267766:WYH_RS00235
uniprot id: A0A0F7KPQ8
names: Similarity
messages: Belongs to the UPF0311 family.

1267766:WYH RS12285
gene id: 1267766:WYH_RS12285
uniprot id: A0A0F7KV53
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1267766:WYH RS06365
gene id: 1267766:WYH_RS06365
uniprot id: A0A0F7KST8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1267766:WYH RS15895
gene id: 1267766:WYH_RS15895
uniprot id: A0A0F7KX41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1267766:WYH RS12380
gene id: 1267766:WYH_RS12380
uniprot id: A0A0F7KT20
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1267766:WYH RS01425
gene id: 1267766:WYH_RS01425
uniprot id: A0A0F7KQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS00365
gene id: 1267766:WYH_RS00365
uniprot id: A0A0F7KPV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1267766:WYH RS00780
gene id: 1267766:WYH_RS00780
uniprot id: A0A0F7KQ23
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1267766:WYH RS09545
gene id: 1267766:WYH_RS09545
uniprot id: A0A0F7KR69
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1267766:WYH RS01670
gene id: 1267766:WYH_RS01670
uniprot id: A0A0F7KPC1
names: Similarity
messages: Belongs to the neutral ceramidase family.

1267766:WYH RS11750
gene id: 1267766:WYH_RS11750
uniprot id: A0A0F7KXB7
names: Similarity
messages: Belongs to the peptidase M1 family.

1267766:WYH RS03120
gene id: 1267766:WYH_RS03120
uniprot id: A0A0F7KM92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1267766:WYH RS03840
gene id: 1267766:WYH_RS03840
uniprot id: A0A0F7KMN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1267766:WYH RS00105
gene id: 1267766:WYH_RS00105
uniprot id: A0A0F7KPR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1267766:WYH RS12170
gene id: 1267766:WYH_RS12170
uniprot id: A0A0F7KV35
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1267766:WYH RS05140
gene id: 1267766:WYH_RS05140
uniprot id: A0A0F7KR61
names: Similarity
messages: Belongs to the OmpW/AlkL family.

1267766:WYH RS15950
gene id: 1267766:WYH_RS15950
uniprot id: A0A0F7KYD3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1267766:WYH RS10705
gene id: 1267766:WYH_RS10705
uniprot id: A0A0F7KVF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1267766:WYH RS11820
gene id: 1267766:WYH_RS11820
uniprot id: A0A0F7KSP8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1267766:WYH RS10305
gene id: 1267766:WYH_RS10305
uniprot id: A0A0F7KWH8
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1267766:WYH RS12815
gene id: 1267766:WYH_RS12815
uniprot id: A0A0F7KTA6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1267766:WYH RS15570
gene id: 1267766:WYH_RS15570
uniprot id: A0A0F7KY80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1267766:WYH RS15900
gene id: 1267766:WYH_RS15900
uniprot id: A0A0F7KZI2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1267766:WYH RS09680
gene id: 1267766:WYH_RS09680
uniprot id: A0A0F7KW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

1267766:WYH RS01765
gene id: 1267766:WYH_RS01765
uniprot id: A0A0F7KQJ6
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1267766:WYH RS08610
gene id: 1267766:WYH_RS08610
uniprot id: A0A0F7KUC3
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS13575
gene id: 1267766:WYH_RS13575
uniprot id: A0A0F7KTQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1267766:WYH RS02465
gene id: 1267766:WYH_RS02465
uniprot id: A0A0F7KPT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS08650
gene id: 1267766:WYH_RS08650
uniprot id: A0A0F7KT69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1267766:WYH RS10455
gene id: 1267766:WYH_RS10455
uniprot id: A0A0F7KVA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1267766:WYH RS07140
gene id: 1267766:WYH_RS07140
uniprot id: A0A0F7KSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1267766:WYH RS13835
gene id: 1267766:WYH_RS13835
uniprot id: A0A0F7KVU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS10785
gene id: 1267766:WYH_RS10785
uniprot id: A0A0F7KRZ3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1267766:WYH RS02515
gene id: 1267766:WYH_RS02515
uniprot id: A0A0F7KPU1
names: Similarity
messages: Belongs to the UPF0102 family.

1267766:WYH RS12015
gene id: 1267766:WYH_RS12015
uniprot id: A0A0F7KST9
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS07455
gene id: 1267766:WYH_RS07455
uniprot id: A0A0F7KTS9
names: Similarity
messages: Belongs to the IlvD/Edd family.

1267766:WYH RS00510
gene id: 1267766:WYH_RS00510
uniprot id: A0A0F7KPW2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1267766:WYH RS04850
gene id: 1267766:WYH_RS04850
uniprot id: A0A0F7KRZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1267766:WYH RS05995
gene id: 1267766:WYH_RS05995
uniprot id: A0A0F7KTZ8
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1267766:WYH RS09630
gene id: 1267766:WYH_RS09630
uniprot id: A0A0F7KW32
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1267766:WYH RS02930
gene id: 1267766:WYH_RS02930
uniprot id: A0A0F7KSB6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1267766:WYH RS13580
gene id: 1267766:WYH_RS13580
uniprot id: A0A0F7KVN9
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS07200
gene id: 1267766:WYH_RS07200
uniprot id: A0A0F7KTN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1267766:WYH RS01085
gene id: 1267766:WYH_RS01085
uniprot id: A0A0F7KQ69
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1267766:WYH RS13190
gene id: 1267766:WYH_RS13190
uniprot id: A0A0F7KWZ3
names: Similarity
messages: Belongs to the peptidase S1C family.

1267766:WYH RS16270
gene id: 1267766:WYH_RS16270
uniprot id: A0A0F7KZS3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1267766:WYH RS03635
gene id: 1267766:WYH_RS03635
uniprot id: A0A0F7KRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1267766:WYH RS00990
gene id: 1267766:WYH_RS00990
uniprot id: A0A0F7KNX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1267766:WYH RS03165
gene id: 1267766:WYH_RS03165
uniprot id: A0A0F7KR86
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1267766:WYH RS13980
gene id: 1267766:WYH_RS13980
uniprot id: A0A0F7KU72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1267766:WYH RS02995
gene id: 1267766:WYH_RS02995
uniprot id: A0A0F7KM70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1267766:WYH RS06620
gene id: 1267766:WYH_RS06620
uniprot id: A0A0F7KT45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1267766:WYH RS08010
gene id: 1267766:WYH_RS08010
uniprot id: A0A0F7KTU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1267766:WYH RS05240
gene id: 1267766:WYH_RS05240
uniprot id: A0A0F7KNL8
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS00455
gene id: 1267766:WYH_RS00455
uniprot id: A0A0F7KQR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1267766:WYH RS05150
gene id: 1267766:WYH_RS05150
uniprot id: A0A0F7KSH7
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1267766:WYH RS07420
gene id: 1267766:WYH_RS07420
uniprot id: A0A0F7KSI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1267766:WYH RS15270
gene id: 1267766:WYH_RS15270
uniprot id: A0A0F7KWS1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS14695
gene id: 1267766:WYH_RS14695
uniprot id: A0A0F7KUH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS03115
gene id: 1267766:WYH_RS03115
uniprot id: A0A0F7KR77
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1267766:WYH RS00875
gene id: 1267766:WYH_RS00875
uniprot id: A0A0F7KQ38
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1267766:WYH RS05145
gene id: 1267766:WYH_RS05145
uniprot id: A0A0F7KTG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1267766:WYH RS02645
gene id: 1267766:WYH_RS02645
uniprot id: A0A0F7KS62
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1267766:WYH RS02575
gene id: 1267766:WYH_RS02575
uniprot id: A0A0F7KR60
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1267766:WYH RS01130
gene id: 1267766:WYH_RS01130
uniprot id: A0A0F7KQ92
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1267766:WYH RS12530
gene id: 1267766:WYH_RS12530
uniprot id: A0A0F7KV97
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1267766:WYH RS10890
gene id: 1267766:WYH_RS10890
uniprot id: A0A0F7KWS0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1267766:WYH RS00915
gene id: 1267766:WYH_RS00915
uniprot id: A0A0F7KNW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1267766:WYH RS03555
gene id: 1267766:WYH_RS03555
uniprot id: A0A0F7KSN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1267766:WYH RS13415
gene id: 1267766:WYH_RS13415
uniprot id: A0A0F7KX14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1267766:WYH RS00310
gene id: 1267766:WYH_RS00310
uniprot id: A0A0F7KPS4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1267766:WYH RS03625
gene id: 1267766:WYH_RS03625
uniprot id: A0A0F7KSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1267766:WYH RS07015
gene id: 1267766:WYH_RS07015
uniprot id: A0A0F7KSC7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1267766:WYH RS06810
gene id: 1267766:WYH_RS06810
uniprot id: A0A0F7KTG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1267766:WYH RS13100
gene id: 1267766:WYH_RS13100
uniprot id: A0A0F7KY06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1267766:WYH RS04010
gene id: 1267766:WYH_RS04010
uniprot id: A0A0F7KRM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1267766:WYH RS15465
gene id: 1267766:WYH_RS15465
uniprot id: A0A0F7KY35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1267766:WYH RS15455
gene id: 1267766:WYH_RS15455
uniprot id: A0A0F7KWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1267766:WYH RS01365
gene id: 1267766:WYH_RS01365
uniprot id: A0A0F7KRD0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1267766:WYH RS06865
gene id: 1267766:WYH_RS06865
uniprot id: A0A0F7KT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1267766:WYH RS02520
gene id: 1267766:WYH_RS02520
uniprot id: A0A0F7KS37
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1267766:WYH RS07130
gene id: 1267766:WYH_RS07130
uniprot id: A0A0F7KTD5
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS05230
gene id: 1267766:WYH_RS05230
uniprot id: A0A0F7KSJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS15075
gene id: 1267766:WYH_RS15075
uniprot id: A0A0F7KXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1267766:WYH RS04460
gene id: 1267766:WYH_RS04460
uniprot id: A0A0F7KQV9
names: Similarity
messages: Belongs to the tannase family.

1267766:WYH RS08130
gene id: 1267766:WYH_RS08130
uniprot id: A0A0F7KVA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1267766:WYH RS06160
gene id: 1267766:WYH_RS06160
uniprot id: A0A0F7KRR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1267766:WYH RS02360
gene id: 1267766:WYH_RS02360
uniprot id: A0A0F7KLX4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1267766:WYH RS11505
gene id: 1267766:WYH_RS11505
uniprot id: A0A0F7KUT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1267766:WYH RS14840
gene id: 1267766:WYH_RS14840
uniprot id: A0A0F7KXR6
names: Similarity
messages: Belongs to the Dps family.

1267766:WYH RS02055
gene id: 1267766:WYH_RS02055
uniprot id: A0A0F7KLS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1267766:WYH RS02080
gene id: 1267766:WYH_RS02080
uniprot id: A0A0F7KLS9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS11045
gene id: 1267766:WYH_RS11045
uniprot id: A0A0F7KWV3
names: Similarity
messages: Belongs to the GARS family.

1267766:WYH RS00040
gene id: 1267766:WYH_RS00040
uniprot id: A0A0F7KYF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1267766:WYH RS01745
gene id: 1267766:WYH_RS01745
uniprot id: A0A0F7KLJ9
names: Similarity
messages: Belongs to the transketolase family.

1267766:WYH RS06045
gene id: 1267766:WYH_RS06045
uniprot id: A0A0F7KU07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1267766:WYH RS01005
gene id: 1267766:WYH_RS01005
uniprot id: A0A0F7KQ59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1267766:WYH RS12700
gene id: 1267766:WYH_RS12700
uniprot id: A0A0F7KXS4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1267766:WYH RS12970
gene id: 1267766:WYH_RS12970
uniprot id: A0A0F7KXY0
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1267766:WYH RS07460
gene id: 1267766:WYH_RS07460
uniprot id: A0A0F7KTI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1267766:WYH RS12940
gene id: 1267766:WYH_RS12940
uniprot id: A0A0F7KVH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1267766:WYH RS11070
gene id: 1267766:WYH_RS11070
uniprot id: A0A0F7KWV8
names: Similarity
messages: Belongs to the HesB/IscA family.

1267766:WYH RS07765
gene id: 1267766:WYH_RS07765
uniprot id: A0A0F7KTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1267766:WYH RS12860
gene id: 1267766:WYH_RS12860
uniprot id: A0A0F7KWP9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1267766:WYH RS08055
gene id: 1267766:WYH_RS08055
uniprot id: A0A0F7KU35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1267766:WYH RS14405
gene id: 1267766:WYH_RS14405
uniprot id: A0A0F7KUE2
names: Similarity
messages: Belongs to the universal stress protein A family.

1267766:WYH RS03275
gene id: 1267766:WYH_RS03275
uniprot id: A0A0F7KQ94
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1267766:WYH RS00495
gene id: 1267766:WYH_RS00495
uniprot id: A0A0F7KKR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1267766:WYH RS04870
gene id: 1267766:WYH_RS04870
uniprot id: A0A0F7KSD5
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1267766:WYH RS13760
gene id: 1267766:WYH_RS13760
uniprot id: A0A0F7KYD6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1267766:WYH RS09265
gene id: 1267766:WYH_RS09265
uniprot id: A0A0F7KR07
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1267766:WYH RS08485
gene id: 1267766:WYH_RS08485
uniprot id: A0A0F7KT32
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1267766:WYH RS06560
gene id: 1267766:WYH_RS06560
uniprot id: A0A0F7KUD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1267766:WYH RS14850
gene id: 1267766:WYH_RS14850
uniprot id: A0A0F7KUK9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1267766:WYH RS16345
gene id: 1267766:WYH_RS16345
uniprot id: A0A0F7KYP0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1267766:WYH RS01335
gene id: 1267766:WYH_RS01335
uniprot id: A0A0F7KP26
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS12920
gene id: 1267766:WYH_RS12920
uniprot id: A0A0F7KVG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1267766:WYH RS09135
gene id: 1267766:WYH_RS09135
uniprot id: A0A0F7KUH6
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1267766:WYH RS01960
gene id: 1267766:WYH_RS01960
uniprot id: A0A0F7KPG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1267766:WYH RS15110
gene id: 1267766:WYH_RS15110
uniprot id: A0A0F7KWP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1267766:WYH RS14980
gene id: 1267766:WYH_RS14980
uniprot id: A0A0F7KWM3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1267766:WYH RS08600
gene id: 1267766:WYH_RS08600
uniprot id: A0A0F7KT60
names: Similarity
messages: Belongs to the asparagine synthetase family.

1267766:WYH RS02550
gene id: 1267766:WYH_RS02550
uniprot id: A0A0F7KR56
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1267766:WYH RS06240
gene id: 1267766:WYH_RS06240
uniprot id: A0A0F7KU45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1267766:WYH RS03055
gene id: 1267766:WYH_RS03055
uniprot id: A0A0F7KSE0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1267766:WYH RS04535
gene id: 1267766:WYH_RS04535
uniprot id: A0A0F7KQX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1267766:WYH RS04035
gene id: 1267766:WYH_RS04035
uniprot id: A0A0F7KRM5
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1267766:WYH RS08300
gene id: 1267766:WYH_RS08300
uniprot id: A0A0F7KT04
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1267766:WYH RS12925
gene id: 1267766:WYH_RS12925
uniprot id: A0A0F7KXX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1267766:WYH RS13705
gene id: 1267766:WYH_RS13705
uniprot id: A0A0F7KVS6
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS06335
gene id: 1267766:WYH_RS06335
uniprot id: A0A0F7KT41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1267766:WYH RS03940
gene id: 1267766:WYH_RS03940
uniprot id: A0A0F7KMQ4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1267766:WYH RS05285
gene id: 1267766:WYH_RS05285
uniprot id: A0A0F7KS66
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1267766:WYH RS00170
gene id: 1267766:WYH_RS00170
uniprot id: A0A0F7KQL6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1267766:WYH RS13530
gene id: 1267766:WYH_RS13530
uniprot id: A0A0F7KY90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

1267766:WYH RS11810
gene id: 1267766:WYH_RS11810
uniprot id: A0A0F7KWA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1267766:WYH RS10085
gene id: 1267766:WYH_RS10085
uniprot id: A0A0F7KV77
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1267766:WYH RS11995
gene id: 1267766:WYH_RS11995
uniprot id: A0A0F7KV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1267766:WYH RS02840
gene id: 1267766:WYH_RS02840
uniprot id: A0A0F7KM52
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1267766:WYH RS02800
gene id: 1267766:WYH_RS02800
uniprot id: A0A0F7KR14
names: Similarity
messages: Belongs to the MreC family.

1267766:WYH RS00740
gene id: 1267766:WYH_RS00740
uniprot id: A0A0F7KNS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1267766:WYH RS05825
gene id: 1267766:WYH_RS05825
uniprot id: A0A0F7KSH8
names: Similarity
messages: Belongs to the GST superfamily.

1267766:WYH RS17255
gene id: 1267766:WYH_RS17255
uniprot id: A0A0F7KTW7
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS02240
gene id: 1267766:WYH_RS02240
uniprot id: A0A0F7KPL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1267766:WYH RS05750
gene id: 1267766:WYH_RS05750
uniprot id: A0A0F7KSG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1267766:WYH RS11960
gene id: 1267766:WYH_RS11960
uniprot id: A0A0F7KW93
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1267766:WYH RS01710
gene id: 1267766:WYH_RS01710
uniprot id: A0A0F7KQJ0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1267766:WYH RS06780
gene id: 1267766:WYH_RS06780
uniprot id: A0A0F7KUG8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1267766:WYH RS14285
gene id: 1267766:WYH_RS14285
uniprot id: A0A0F7KW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1267766:WYH RS07115
gene id: 1267766:WYH_RS07115
uniprot id: A0A0F7KSE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1267766:WYH RS15135
gene id: 1267766:WYH_RS15135
uniprot id: A0A0F7KWP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1267766:WYH RS14035
gene id: 1267766:WYH_RS14035
uniprot id: A0A0F7KW07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1267766:WYH RS09760
gene id: 1267766:WYH_RS09760
uniprot id: A0A0F7KV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1267766:WYH RS05495
gene id: 1267766:WYH_RS05495
uniprot id: A0A0F7KTN2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1267766:WYH RS06605
gene id: 1267766:WYH_RS06605
uniprot id: A0A0F7KS49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1267766:WYH RS00195
gene id: 1267766:WYH_RS00195
uniprot id: A0A0F7KQM0
names: Similarity
messages: Belongs to the ArsC family.

1267766:WYH RS12120
gene id: 1267766:WYH_RS12120
uniprot id: A0A0F7KV29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1267766:WYH RS11160
gene id: 1267766:WYH_RS11160
uniprot id: A0A0F7KUL2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1267766:WYH RS05180
gene id: 1267766:WYH_RS05180
uniprot id: A0A0F7KSI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1267766:WYH RS10015
gene id: 1267766:WYH_RS10015
uniprot id: A0A0F7KV06
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1267766:WYH RS04865
gene id: 1267766:WYH_RS04865
uniprot id: A0A0F7KTB3
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1267766:WYH RS10565
gene id: 1267766:WYH_RS10565
uniprot id: A0A0F7KRT8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1267766:WYH RS06565
gene id: 1267766:WYH_RS06565
uniprot id: A0A0F7KTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1267766:WYH RS15660
gene id: 1267766:WYH_RS15660
uniprot id: A0A0F7KZD3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS04595
gene id: 1267766:WYH_RS04595
uniprot id: A0A0F7KS83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1267766:WYH RS02590
gene id: 1267766:WYH_RS02590
uniprot id: A0A0F7KPV2
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS06760
gene id: 1267766:WYH_RS06760
uniprot id: A0A0F7KTF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1267766:WYH RS01495
gene id: 1267766:WYH_RS01495
uniprot id: A0A0F7KQL0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1267766:WYH RS03965
gene id: 1267766:WYH_RS03965
uniprot id: A0A0F7KMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1267766:WYH RS11635
gene id: 1267766:WYH_RS11635
uniprot id: A0A0F7KX93
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1267766:WYH RS06545
gene id: 1267766:WYH_RS06545
uniprot id: A0A0F7KPF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1267766:WYH RS05730
gene id: 1267766:WYH_RS05730
uniprot id: A0A0F7KNY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1267766:WYH RS09440
gene id: 1267766:WYH_RS09440
uniprot id: A0A0F7KUM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1267766:WYH RS15935
gene id: 1267766:WYH_RS15935
uniprot id: A0A0F7KV84
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1267766:WYH RS11890
gene id: 1267766:WYH_RS11890
uniprot id: A0A0F7KW76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1267766:WYH RS11855
gene id: 1267766:WYH_RS11855
uniprot id: A0A0F7KXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1267766:WYH RS06870
gene id: 1267766:WYH_RS06870
uniprot id: A0A0F7KPL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1267766:WYH RS13515
gene id: 1267766:WYH_RS13515
uniprot id: A0A0F7KX33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1267766:WYH RS06155
gene id: 1267766:WYH_RS06155
uniprot id: A0A0F7KP43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1267766:WYH RS00055
gene id: 1267766:WYH_RS00055
uniprot id: A0A0F7KX70
names: Similarity
messages: Belongs to the SufE family.

1267766:WYH RS15315
gene id: 1267766:WYH_RS15315
uniprot id: A0A0F7KUT6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1267766:WYH RS08215
gene id: 1267766:WYH_RS08215
uniprot id: A0A0F7KQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1267766:WYH RS02715
gene id: 1267766:WYH_RS02715
uniprot id: A0A0F7KS77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1267766:WYH RS06355
gene id: 1267766:WYH_RS06355
uniprot id: A0A0F7KU70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1267766:WYH RS15205
gene id: 1267766:WYH_RS15205
uniprot id: A0A0F7KY08
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1267766:WYH RS12040
gene id: 1267766:WYH_RS12040
uniprot id: A0A0F7KSU2
names: Similarity
messages: Belongs to the peptidase C40 family.

1267766:WYH RS12355
gene id: 1267766:WYH_RS12355
uniprot id: A0A0F7KT17
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1267766:WYH RS00505
gene id: 1267766:WYH_RS00505
uniprot id: A0A0F7KQS3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1267766:WYH RS06875
gene id: 1267766:WYH_RS06875
uniprot id: A0A0F7KUI6
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS06300
gene id: 1267766:WYH_RS06300
uniprot id: A0A0F7KP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1267766:WYH RS00390
gene id: 1267766:WYH_RS00390
uniprot id: A0A0F7KPV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1267766:WYH RS05570
gene id: 1267766:WYH_RS05570
uniprot id: A0A0F7KTQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1267766:WYH RS03445
gene id: 1267766:WYH_RS03445
uniprot id: A0A0F7KMG4
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS00905
gene id: 1267766:WYH_RS00905
uniprot id: A0A0F7KQ44
names: Function
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1267766:WYH RS05035
gene id: 1267766:WYH_RS05035
uniprot id: A0A0F7KR42
names: Similarity
messages: Belongs to the pirin family.

1267766:WYH RS05985
gene id: 1267766:WYH_RS05985
uniprot id: A0A0F7KP17
names: Similarity
messages: Belongs to the peptidase M16 family.

1267766:WYH RS13020
gene id: 1267766:WYH_RS13020
uniprot id: A0A0F7KXZ1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1267766:WYH RS08175
gene id: 1267766:WYH_RS08175
uniprot id: A0A0F7KSY8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1267766:WYH RS15115
gene id: 1267766:WYH_RS15115
uniprot id: A0A0F7KZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1267766:WYH RS02225
gene id: 1267766:WYH_RS02225
uniprot id: A0A0F7KQY5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1267766:WYH RS04355
gene id: 1267766:WYH_RS04355
uniprot id: A0A0F7KT25
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1267766:WYH RS09985
gene id: 1267766:WYH_RS09985
uniprot id: A0A0F7KV59
names: Similarity
messages: Belongs to the Gfa family.

1267766:WYH RS03095
gene id: 1267766:WYH_RS03095
uniprot id: A0A0F7KM87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1267766:WYH RS10360
gene id: 1267766:WYH_RS10360
uniprot id: A0A0F7KV82
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1267766:WYH RS02500
gene id: 1267766:WYH_RS02500
uniprot id: A0A0F7KR47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1267766:WYH RS00800
gene id: 1267766:WYH_RS00800
uniprot id: A0A0F7KQ27
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1267766:WYH RS00350
gene id: 1267766:WYH_RS00350
uniprot id: A0A0F7KNJ2
names: Similarity
messages: Belongs to the universal stress protein A family.

1267766:WYH RS13160
gene id: 1267766:WYH_RS13160
uniprot id: A0A0F7KSW3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1267766:WYH RS00940
gene id: 1267766:WYH_RS00940
uniprot id: A0A0F7KNX2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1267766:WYH RS00360
gene id: 1267766:WYH_RS00360
uniprot id: A0A0F7KPT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1267766:WYH RS14665
gene id: 1267766:WYH_RS14665
uniprot id: A0A0F7KXQ3
names: Similarity
messages: Belongs to the oxoprolinase family.

1267766:WYH RS03005
gene id: 1267766:WYH_RS03005
uniprot id: A0A0F7KSD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1267766:WYH RS14200
gene id: 1267766:WYH_RS14200
uniprot id: A0A0F7KXI6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1267766:WYH RS00590
gene id: 1267766:WYH_RS00590
uniprot id: A0A0F7KKU2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1267766:WYH RS11325
gene id: 1267766:WYH_RS11325
uniprot id: A0A0F7KSA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1267766:WYH RS00460
gene id: 1267766:WYH_RS00460
uniprot id: A0A0F7KPV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1267766:WYH RS00895
gene id: 1267766:WYH_RS00895
uniprot id: A0A0F7KR01
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1267766:WYH RS05875
gene id: 1267766:WYH_RS05875
uniprot id: A0A0F7KSW7
names: Similarity
messages: Belongs to the UPF0311 family.

1267766:WYH RS16060
gene id: 1267766:WYH_RS16060
uniprot id: A0A0F7KVQ1
names: Similarity
messages: Belongs to the ParB family.

1267766:WYH RS09465
gene id: 1267766:WYH_RS09465
uniprot id: A0A0F7KUN3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1267766:WYH RS16115
gene id: 1267766:WYH_RS16115
uniprot id: A0A0F7KVF8
names: Subcellular Location Annotation
messages: Membrane

1267766:WYH RS15595
gene id: 1267766:WYH_RS15595
uniprot id: A0A0F7KY87
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1267766:WYH RS15545
gene id: 1267766:WYH_RS15545
uniprot id: A0A0F7KY77
names: Similarity
messages: Belongs to the MotB family.

1267766:WYH RS05010
gene id: 1267766:WYH_RS05010
uniprot id: A0A0F7KR38
names: Similarity
messages: Belongs to the GST superfamily.

1267766:WYH RS04330
gene id: 1267766:WYH_RS04330
uniprot id: A0A0F7KS38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1267766:WYH RS03600
gene id: 1267766:WYH_RS03600
uniprot id: A0A0F7KSQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1267766:WYH RS06580
gene id: 1267766:WYH_RS06580
uniprot id: A0A0F7KS45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1267766:WYH RS06110
gene id: 1267766:WYH_RS06110
uniprot id: A0A0F7KRQ2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.