1236518:AXF22 RS04025
gene id: 1236518:AXF22_RS04025
uniprot id: A0A1B1I793
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS05590
gene id: 1236518:AXF22_RS05590
uniprot id: A0A1B1I818
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1236518:AXF22 RS01445
gene id: 1236518:AXF22_RS01445
uniprot id: A0A1B1I600
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS00055
gene id: 1236518:AXF22_RS00055
uniprot id: A0A1B1I597
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1236518:AXF22 RS04245
gene id: 1236518:AXF22_RS04245
uniprot id: A0A1B1I7E2
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1236518:AXF22 RS04555
gene id: 1236518:AXF22_RS04555
uniprot id: A0A1B1I7J2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1236518:AXF22 RS01450
gene id: 1236518:AXF22_RS01450
uniprot id: A0A1B1I604
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS11475
gene id: 1236518:AXF22_RS11475
uniprot id: A0A1B1IBA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1236518:AXF22 RS05040
gene id: 1236518:AXF22_RS05040
uniprot id: A0A1B1I7S0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1236518:AXF22 RS03810
gene id: 1236518:AXF22_RS03810
uniprot id: A0A1B1I760
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1236518:AXF22 RS09560
gene id: 1236518:AXF22_RS09560
uniprot id: A0A1B1IAB0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1236518:AXF22 RS12570
gene id: 1236518:AXF22_RS12570
uniprot id: A0A1B1IBZ6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1236518:AXF22 RS04275
gene id: 1236518:AXF22_RS04275
uniprot id: A0A1B1I7E0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1236518:AXF22 RS04395
gene id: 1236518:AXF22_RS04395
uniprot id: A0A1B1I7G0
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1236518:AXF22 RS02635
gene id: 1236518:AXF22_RS02635
uniprot id: A0A1B1I6N0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1236518:AXF22 RS03015
gene id: 1236518:AXF22_RS03015
uniprot id: A0A1B1I6S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1236518:AXF22 RS07705
gene id: 1236518:AXF22_RS07705
uniprot id: A0A1B1IC47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS09325
gene id: 1236518:AXF22_RS09325
uniprot id: A0A1B1IA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS11600
gene id: 1236518:AXF22_RS11600
uniprot id: A0A1B1IBD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1236518:AXF22 RS08085
gene id: 1236518:AXF22_RS08085
uniprot id: A0A1B1I9T3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1236518:AXF22 RS04015
gene id: 1236518:AXF22_RS04015
uniprot id: A0A1B1I788
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS00995
gene id: 1236518:AXF22_RS00995
uniprot id: A0A1B1I5U2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1236518:AXF22 RS01955
gene id: 1236518:AXF22_RS01955
uniprot id: A0A1B1I979
names: Similarity
messages: Belongs to the Skp family.

1236518:AXF22 RS02885
gene id: 1236518:AXF22_RS02885
uniprot id: A0A1B1I940
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1236518:AXF22 RS07845
gene id: 1236518:AXF22_RS07845
uniprot id: A0A1B1I9L5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1236518:AXF22 RS07020
gene id: 1236518:AXF22_RS07020
uniprot id: A0A1B1I8P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1236518:AXF22 RS08640
gene id: 1236518:AXF22_RS08640
uniprot id: A0A1B1I9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1236518:AXF22 RS03045
gene id: 1236518:AXF22_RS03045
uniprot id: A0A1B1I6V3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1236518:AXF22 RS02355
gene id: 1236518:AXF22_RS02355
uniprot id: A0A1B1I6G0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1236518:AXF22 RS04000
gene id: 1236518:AXF22_RS04000
uniprot id: A0A1B1I7D2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1236518:AXF22 RS10625
gene id: 1236518:AXF22_RS10625
uniprot id: A0A1B1IAU6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

1236518:AXF22 RS00445
gene id: 1236518:AXF22_RS00445
uniprot id: A0A1B1I5I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1236518:AXF22 RS06580
gene id: 1236518:AXF22_RS06580
uniprot id: A0A1B1I8M4
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS00865
gene id: 1236518:AXF22_RS00865
uniprot id: A0A1B1I5P6
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS04320
gene id: 1236518:AXF22_RS04320
uniprot id: A0A1B1I7E4
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS01570
gene id: 1236518:AXF22_RS01570
uniprot id: A0A1B1I680
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1236518:AXF22 RS11930
gene id: 1236518:AXF22_RS11930
uniprot id: A0A1B1IBE5
names: Similarity
messages: Belongs to the fabD family.

1236518:AXF22 RS12060
gene id: 1236518:AXF22_RS12060
uniprot id: A0A1B1IBK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1236518:AXF22 RS09650
gene id: 1236518:AXF22_RS09650
uniprot id: A0A1B1IAB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS00960
gene id: 1236518:AXF22_RS00960
uniprot id: A0A1B1I5R0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1236518:AXF22 RS04525
gene id: 1236518:AXF22_RS04525
uniprot id: A0A1B1I7J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1236518:AXF22 RS02365
gene id: 1236518:AXF22_RS02365
uniprot id: A0A1B1I6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1236518:AXF22 RS12460
gene id: 1236518:AXF22_RS12460
uniprot id: A0A1B1IBY1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1236518:AXF22 RS07490
gene id: 1236518:AXF22_RS07490
uniprot id: A0A1B1I8Z3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS01110
gene id: 1236518:AXF22_RS01110
uniprot id: A0A1B1I5V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1236518:AXF22 RS11880
gene id: 1236518:AXF22_RS11880
uniprot id: A0A1B1IBJ5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1236518:AXF22 RS08915
gene id: 1236518:AXF22_RS08915
uniprot id: A0A1B1IA15
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1236518:AXF22 RS06035
gene id: 1236518:AXF22_RS06035
uniprot id: A0A1B1I888
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1236518:AXF22 RS03910
gene id: 1236518:AXF22_RS03910
uniprot id: A0A1B1I779
names: Similarity
messages: Belongs to the peptidase C1 family.

1236518:AXF22 RS05515
gene id: 1236518:AXF22_RS05515
uniprot id: A0A1B1I7Z7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1236518:AXF22 RS04425
gene id: 1236518:AXF22_RS04425
uniprot id: A0A1B1I7H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1236518:AXF22 RS01730
gene id: 1236518:AXF22_RS01730
uniprot id: A0A1B1I646
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS06985
gene id: 1236518:AXF22_RS06985
uniprot id: A0A1B1I8P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1236518:AXF22 RS08035
gene id: 1236518:AXF22_RS08035
uniprot id: A0A1B1I9N6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1236518:AXF22 RS11900
gene id: 1236518:AXF22_RS11900
uniprot id: A0A1B1IBF4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1236518:AXF22 RS08860
gene id: 1236518:AXF22_RS08860
uniprot id: A0A1B1I9Y6
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS07995
gene id: 1236518:AXF22_RS07995
uniprot id: A0A1B1I9J3
names: Similarity
messages: Belongs to the serpin family.

1236518:AXF22 RS00420
gene id: 1236518:AXF22_RS00420
uniprot id: A0A1B1I5J1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1236518:AXF22 RS07930
gene id: 1236518:AXF22_RS07930
uniprot id: A0A1B1I9N8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1236518:AXF22 RS06525
gene id: 1236518:AXF22_RS06525
uniprot id: A0A1B1I8G5
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS03935
gene id: 1236518:AXF22_RS03935
uniprot id: A0A1B1I777
names: Subcellular Location Annotation
messages: Nucleus

1236518:AXF22 RS05880
gene id: 1236518:AXF22_RS05880
uniprot id: A0A1B1I879
names: Similarity
messages: Belongs to the peptidase S14 family.

1236518:AXF22 RS07265
gene id: 1236518:AXF22_RS07265
uniprot id: A0A1B1I8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS01205
gene id: 1236518:AXF22_RS01205
uniprot id: A0A1B1I5X5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS00130
gene id: 1236518:AXF22_RS00130
uniprot id: A0A1B1I5H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1236518:AXF22 RS04955
gene id: 1236518:AXF22_RS04955
uniprot id: A0A1B1I7W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1236518:AXF22 RS03025
gene id: 1236518:AXF22_RS03025
uniprot id: A0A1B1I6S5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1236518:AXF22 RS06030
gene id: 1236518:AXF22_RS06030
uniprot id: A0A1B1I886
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1236518:AXF22 RS12230
gene id: 1236518:AXF22_RS12230
uniprot id: A0A1B1IBL3
names: Similarity
messages: Belongs to the peptidase S9A family.

1236518:AXF22 RS01035
gene id: 1236518:AXF22_RS01035
uniprot id: A0A1B1I5T3
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS12200
gene id: 1236518:AXF22_RS12200
uniprot id: A0A1B1IBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1236518:AXF22 RS01180
gene id: 1236518:AXF22_RS01180
uniprot id: A0A1B1I5X0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1236518:AXF22 RS03800
gene id: 1236518:AXF22_RS03800
uniprot id: A0A1B1I750
names: Similarity
messages: Belongs to the ParB family.

1236518:AXF22 RS03995
gene id: 1236518:AXF22_RS03995
uniprot id: A0A1B1I790
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS00440
gene id: 1236518:AXF22_RS00440
uniprot id: A0A1B1I5J3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1236518:AXF22 RS05640
gene id: 1236518:AXF22_RS05640
uniprot id: A0A1B1I819
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1236518:AXF22 RS03150
gene id: 1236518:AXF22_RS03150
uniprot id: A0A1B1I6X2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1236518:AXF22 RS12500
gene id: 1236518:AXF22_RS12500
uniprot id: A0A1B1IBQ1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1236518:AXF22 RS07205
gene id: 1236518:AXF22_RS07205
uniprot id: A0A1B1I8T7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS02625
gene id: 1236518:AXF22_RS02625
uniprot id: A0A1B1I6K9
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1236518:AXF22 RS01265
gene id: 1236518:AXF22_RS01265
uniprot id: A0A1B1I5Y5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS07550
gene id: 1236518:AXF22_RS07550
uniprot id: A0A1B1I9B5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1236518:AXF22 RS08890
gene id: 1236518:AXF22_RS08890
uniprot id: A0A1B1IA16
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1236518:AXF22 RS01210
gene id: 1236518:AXF22_RS01210
uniprot id: A0A1B1I5W0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1236518:AXF22 RS06765
gene id: 1236518:AXF22_RS06765
uniprot id: A0A1B1I8K3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1236518:AXF22 RS12285
gene id: 1236518:AXF22_RS12285
uniprot id: A0A1B1IBQ4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1236518:AXF22 RS09630
gene id: 1236518:AXF22_RS09630
uniprot id: A0A1B1IAB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1236518:AXF22 RS01410
gene id: 1236518:AXF22_RS01410
uniprot id: A0A1B1I610
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1236518:AXF22 RS12670
gene id: 1236518:AXF22_RS12670
uniprot id: A0A1B1IBV0
names: Similarity
messages: Belongs to the IMPACT family.

1236518:AXF22 RS06895
gene id: 1236518:AXF22_RS06895
uniprot id: A0A1B1I8P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1236518:AXF22 RS12950
gene id: 1236518:AXF22_RS12950
uniprot id: A0A1B1IC01
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1236518:AXF22 RS07445
gene id: 1236518:AXF22_RS07445
uniprot id: A0A1B1I9E9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1236518:AXF22 RS08525
gene id: 1236518:AXF22_RS08525
uniprot id: A0A1B1IA00
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS06145
gene id: 1236518:AXF22_RS06145
uniprot id: A0A1B1I898
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS06550
gene id: 1236518:AXF22_RS06550
uniprot id: A0A1B1I8G8
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS10360
gene id: 1236518:AXF22_RS10360
uniprot id: A0A1B1IAQ6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1236518:AXF22 RS04105
gene id: 1236518:AXF22_RS04105
uniprot id: A0A1B1I7A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1236518:AXF22 RS00965
gene id: 1236518:AXF22_RS00965
uniprot id: A0A1B1I5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1236518:AXF22 RS11790
gene id: 1236518:AXF22_RS11790
uniprot id: A0A1B1IBC9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1236518:AXF22 RS03505
gene id: 1236518:AXF22_RS03505
uniprot id: A0A1B1I6Z5
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS07095
gene id: 1236518:AXF22_RS07095
uniprot id: A0A1B1I8R2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1236518:AXF22 RS08905
gene id: 1236518:AXF22_RS08905
uniprot id: A0A1B1IA49
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS09015
gene id: 1236518:AXF22_RS09015
uniprot id: A0A1B1IA45
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1236518:AXF22 RS03380
gene id: 1236518:AXF22_RS03380
uniprot id: A0A1B1I721
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1236518:AXF22 RS00035
gene id: 1236518:AXF22_RS00035
uniprot id: A0A1B1I5A2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1236518:AXF22 RS01480
gene id: 1236518:AXF22_RS01480
uniprot id: A0A1B1I662
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1236518:AXF22 RS05445
gene id: 1236518:AXF22_RS05445
uniprot id: A0A1B1I7Z3
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS04490
gene id: 1236518:AXF22_RS04490
uniprot id: A0A1B1I7H1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS02160
gene id: 1236518:AXF22_RS02160
uniprot id: A0A1B1I6C2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1236518:AXF22 RS12710
gene id: 1236518:AXF22_RS12710
uniprot id: A0A1B1IBW6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1236518:AXF22 RS01370
gene id: 1236518:AXF22_RS01370
uniprot id: A0A1B1I5Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1236518:AXF22 RS09605
gene id: 1236518:AXF22_RS09605
uniprot id: A0A1B1IAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1236518:AXF22 RS01055
gene id: 1236518:AXF22_RS01055
uniprot id: A0A1B1I5V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1236518:AXF22 RS10655
gene id: 1236518:AXF22_RS10655
uniprot id: A0A1B1IAT1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1236518:AXF22 RS00085
gene id: 1236518:AXF22_RS00085
uniprot id: A0A1B1I5D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1236518:AXF22 RS03940
gene id: 1236518:AXF22_RS03940
uniprot id: A0A1B1I7B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1236518:AXF22 RS08135
gene id: 1236518:AXF22_RS08135
uniprot id: A0A1B1I9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS00755
gene id: 1236518:AXF22_RS00755
uniprot id: A0A1B1I5M5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1236518:AXF22 RS00670
gene id: 1236518:AXF22_RS00670
uniprot id: A0A1B1I5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1236518:AXF22 RS07655
gene id: 1236518:AXF22_RS07655
uniprot id: A0A1B1I9D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS06975
gene id: 1236518:AXF22_RS06975
uniprot id: A0A1B1I8U2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1236518:AXF22 RS09635
gene id: 1236518:AXF22_RS09635
uniprot id: A0A1B1IAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1236518:AXF22 RS08355
gene id: 1236518:AXF22_RS08355
uniprot id: A0A1B1I9Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1236518:AXF22 RS08815
gene id: 1236518:AXF22_RS08815
uniprot id: A0A1B1IA18
names: Similarity
messages: Belongs to the pyruvate kinase family.

1236518:AXF22 RS00500
gene id: 1236518:AXF22_RS00500
uniprot id: A0A1B1I5K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1236518:AXF22 RS12955
gene id: 1236518:AXF22_RS12955
uniprot id: A0A1B1IC24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1236518:AXF22 RS09515
gene id: 1236518:AXF22_RS09515
uniprot id: A0A1B1IA97
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS05530
gene id: 1236518:AXF22_RS05530
uniprot id: A0A1B1I984
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1236518:AXF22 RS06120
gene id: 1236518:AXF22_RS06120
uniprot id: A0A1B1I8A8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1236518:AXF22 RS07210
gene id: 1236518:AXF22_RS07210
uniprot id: A0A1B1I8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1236518:AXF22 RS04500
gene id: 1236518:AXF22_RS04500
uniprot id: A0A1B1I7I1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1236518:AXF22 RS06410
gene id: 1236518:AXF22_RS06410
uniprot id: A0A1B1I8E4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1236518:AXF22 RS04310
gene id: 1236518:AXF22_RS04310
uniprot id: A0A1B1I7D9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS10355
gene id: 1236518:AXF22_RS10355
uniprot id: A0A1B1IAP4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1236518:AXF22 RS02780
gene id: 1236518:AXF22_RS02780
uniprot id: A0A1B1I6N2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1236518:AXF22 RS11170
gene id: 1236518:AXF22_RS11170
uniprot id: A0A1B1IB32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1236518:AXF22 RS11960
gene id: 1236518:AXF22_RS11960
uniprot id: A0A1B1IBF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS06980
gene id: 1236518:AXF22_RS06980
uniprot id: A0A1B1I8N8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1236518:AXF22 RS06415
gene id: 1236518:AXF22_RS06415
uniprot id: A0A1B1I8F0
names: Similarity
messages: Belongs to the peptidase S8 family.

1236518:AXF22 RS05475
gene id: 1236518:AXF22_RS05475
uniprot id: A0A1B1I7Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1236518:AXF22 RS06655
gene id: 1236518:AXF22_RS06655
uniprot id: A0A1B1I8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1236518:AXF22 RS10045
gene id: 1236518:AXF22_RS10045
uniprot id: A0A1B1IAS6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1236518:AXF22 RS12960
gene id: 1236518:AXF22_RS12960
uniprot id: A0A1B1IC63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1236518:AXF22 RS06440
gene id: 1236518:AXF22_RS06440
uniprot id: A0A1B1I8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS07725
gene id: 1236518:AXF22_RS07725
uniprot id: A0A1B1I9E4
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS07740
gene id: 1236518:AXF22_RS07740
uniprot id: A0A1B1I9F3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS03885
gene id: 1236518:AXF22_RS03885
uniprot id: A0A1B1I786
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1236518:AXF22 RS12075
gene id: 1236518:AXF22_RS12075
uniprot id: A0A1B1IBI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1236518:AXF22 RS07980
gene id: 1236518:AXF22_RS07980
uniprot id: A0A1B1I9M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1236518:AXF22 RS11095
gene id: 1236518:AXF22_RS11095
uniprot id: A0A1B1IB60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1236518:AXF22 RS06140
gene id: 1236518:AXF22_RS06140
uniprot id: A0A1B1I8B6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1236518:AXF22 RS03070
gene id: 1236518:AXF22_RS03070
uniprot id: A0A1B1I6T7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1236518:AXF22 RS03215
gene id: 1236518:AXF22_RS03215
uniprot id: A0A1B1I6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS07425
gene id: 1236518:AXF22_RS07425
uniprot id: A0A1B1I8X3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1236518:AXF22 RS03815
gene id: 1236518:AXF22_RS03815
uniprot id: A0A1B1I747
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1236518:AXF22 RS04950
gene id: 1236518:AXF22_RS04950
uniprot id: A0A1B1I7R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1236518:AXF22 RS10410
gene id: 1236518:AXF22_RS10410
uniprot id: A0A1B1IAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS08025
gene id: 1236518:AXF22_RS08025
uniprot id: A0A1B1I9S0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS04140
gene id: 1236518:AXF22_RS04140
uniprot id: A0A1B1I7E9
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS02360
gene id: 1236518:AXF22_RS02360
uniprot id: A0A1B1I6F7
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1236518:AXF22 RS05425
gene id: 1236518:AXF22_RS05425
uniprot id: A0A1B1I7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1236518:AXF22 RS04160
gene id: 1236518:AXF22_RS04160
uniprot id: A0A1B1I7C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1236518:AXF22 RS12445
gene id: 1236518:AXF22_RS12445
uniprot id: A0A1B1IBP2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1236518:AXF22 RS11635
gene id: 1236518:AXF22_RS11635
uniprot id: A0A1B1IBC5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1236518:AXF22 RS03670
gene id: 1236518:AXF22_RS03670
uniprot id: A0A1B1I736
names: Similarity
messages: Belongs to the ribF family.

1236518:AXF22 RS02130
gene id: 1236518:AXF22_RS02130
uniprot id: A0A1B1I6D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1236518:AXF22 RS04350
gene id: 1236518:AXF22_RS04350
uniprot id: A0A1B1I7E5
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS01775
gene id: 1236518:AXF22_RS01775
uniprot id: A0A1B1I667
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1236518:AXF22 RS02975
gene id: 1236518:AXF22_RS02975
uniprot id: A0A1B1I6Q6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1236518:AXF22 RS06285
gene id: 1236518:AXF22_RS06285
uniprot id: A0A1B1I8C4
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1236518:AXF22 RS11510
gene id: 1236518:AXF22_RS11510
uniprot id: A0A1B1IB74
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

1236518:AXF22 RS07810
gene id: 1236518:AXF22_RS07810
uniprot id: A0A1B1I9J6
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS00475
gene id: 1236518:AXF22_RS00475
uniprot id: A0A1B1I5H6
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS05665
gene id: 1236518:AXF22_RS05665
uniprot id: A0A1B1I816
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1236518:AXF22 RS06950
gene id: 1236518:AXF22_RS06950
uniprot id: A0A1B1I8Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1236518:AXF22 RS01565
gene id: 1236518:AXF22_RS01565
uniprot id: A0A1B1I623
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1236518:AXF22 RS07600
gene id: 1236518:AXF22_RS07600
uniprot id: A0A1B1I9F7
names: Similarity
messages: Belongs to the peptidase S51 family.

1236518:AXF22 RS06615
gene id: 1236518:AXF22_RS06615
uniprot id: A0A1B1I8J6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1236518:AXF22 RS07230
gene id: 1236518:AXF22_RS07230
uniprot id: A0A1B1I8Y7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1236518:AXF22 RS02500
gene id: 1236518:AXF22_RS02500
uniprot id: A0A1B1I6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS07755
gene id: 1236518:AXF22_RS07755
uniprot id: A0A1B1I9F0
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS12315
gene id: 1236518:AXF22_RS12315
uniprot id: A0A1B1IBP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1236518:AXF22 RS12305
gene id: 1236518:AXF22_RS12305
uniprot id: A0A1B1IBK4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1236518:AXF22 RS07250
gene id: 1236518:AXF22_RS07250
uniprot id: A0A1B1I8T0
names: Similarity
messages: Belongs to the RutC family.

1236518:AXF22 RS00955
gene id: 1236518:AXF22_RS00955
uniprot id: A0A1B1I5R6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1236518:AXF22 RS05325
gene id: 1236518:AXF22_RS05325
uniprot id: A0A1B1I7X0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1236518:AXF22 RS00460
gene id: 1236518:AXF22_RS00460
uniprot id: A0A1B1I5J2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS06805
gene id: 1236518:AXF22_RS06805
uniprot id: A0A1B1I8N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1236518:AXF22 RS12840
gene id: 1236518:AXF22_RS12840
uniprot id: A0A1B1IBX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1236518:AXF22 RS06170
gene id: 1236518:AXF22_RS06170
uniprot id: A0A1B1I991
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS09435
gene id: 1236518:AXF22_RS09435
uniprot id: A0A1B1IAD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1236518:AXF22 RS12575
gene id: 1236518:AXF22_RS12575
uniprot id: A0A1B1IBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1236518:AXF22 RS04120
gene id: 1236518:AXF22_RS04120
uniprot id: A0A1B1I7F1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1236518:AXF22 RS11520
gene id: 1236518:AXF22_RS11520
uniprot id: A0A1B1IB94
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

1236518:AXF22 RS06940
gene id: 1236518:AXF22_RS06940
uniprot id: A0A1B1I8N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1236518:AXF22 RS12580
gene id: 1236518:AXF22_RS12580
uniprot id: A0A1B1IBT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1236518:AXF22 RS08300
gene id: 1236518:AXF22_RS08300
uniprot id: A0A1B1I9P2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1236518:AXF22 RS02135
gene id: 1236518:AXF22_RS02135
uniprot id: A0A1B1I6G8
names: Similarity
messages: Belongs to the peptidase M16 family.

1236518:AXF22 RS07715
gene id: 1236518:AXF22_RS07715
uniprot id: A0A1B1I9E1
names: Similarity
messages: Belongs to the asparaginase 1 family.

1236518:AXF22 RS07960
gene id: 1236518:AXF22_RS07960
uniprot id: A0A1B1I9Q5
names: Similarity
messages: Belongs to the peptidase C69 family.

1236518:AXF22 RS00675
gene id: 1236518:AXF22_RS00675
uniprot id: A0A1B1I5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1236518:AXF22 RS11910
gene id: 1236518:AXF22_RS11910
uniprot id: A0A1B1IBE1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1236518:AXF22 RS10565
gene id: 1236518:AXF22_RS10565
uniprot id: A0A1B1IAT8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS07450
gene id: 1236518:AXF22_RS07450
uniprot id: A0A1B1I8Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1236518:AXF22 RS00255
gene id: 1236518:AXF22_RS00255
uniprot id: A0A1B1I5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1236518:AXF22 RS08715
gene id: 1236518:AXF22_RS08715
uniprot id: A0A1B1I9W4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1236518:AXF22 RS12360
gene id: 1236518:AXF22_RS12360
uniprot id: A0A1B1IBL7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1236518:AXF22 RS02350
gene id: 1236518:AXF22_RS02350
uniprot id: A0A1B1I6L4
names: Similarity
messages: Belongs to the UPF0597 family.

1236518:AXF22 RS04295
gene id: 1236518:AXF22_RS04295
uniprot id: A0A1B1I7I5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1236518:AXF22 RS11620
gene id: 1236518:AXF22_RS11620
uniprot id: A0A1B1IB93
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS12410
gene id: 1236518:AXF22_RS12410
uniprot id: A0A1B1IBX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

1236518:AXF22 RS02075
gene id: 1236518:AXF22_RS02075
uniprot id: A0A1B1I6F9
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1236518:AXF22 RS11695
gene id: 1236518:AXF22_RS11695
uniprot id: A0A1B1IBB3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS08830
gene id: 1236518:AXF22_RS08830
uniprot id: A0A1B1IA08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1236518:AXF22 RS04050
gene id: 1236518:AXF22_RS04050
uniprot id: A0A1B1I7E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1236518:AXF22 RS04420
gene id: 1236518:AXF22_RS04420
uniprot id: A0A1B1I7H0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1236518:AXF22 RS10155
gene id: 1236518:AXF22_RS10155
uniprot id: A0A1B1IAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS00245
gene id: 1236518:AXF22_RS00245
uniprot id: A0A1B1I5F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1236518:AXF22 RS11200
gene id: 1236518:AXF22_RS11200
uniprot id: A0A1B1IB23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1236518:AXF22 RS12010
gene id: 1236518:AXF22_RS12010
uniprot id: A0A1B1IBG1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1236518:AXF22 RS05380
gene id: 1236518:AXF22_RS05380
uniprot id: A0A1B1I7X3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1236518:AXF22 RS12870
gene id: 1236518:AXF22_RS12870
uniprot id: A0A1B1IBW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1236518:AXF22 RS11085
gene id: 1236518:AXF22_RS11085
uniprot id: A0A1B1IB19
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1236518:AXF22 RS05695
gene id: 1236518:AXF22_RS05695
uniprot id: A0A1B1I843
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1236518:AXF22 RS06820
gene id: 1236518:AXF22_RS06820
uniprot id: A0A1B1I8K6
names: Similarity
messages: Belongs to the thioredoxin family.

1236518:AXF22 RS07395
gene id: 1236518:AXF22_RS07395
uniprot id: A0A1B1I8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1236518:AXF22 RS00820
gene id: 1236518:AXF22_RS00820
uniprot id: A0A1B1I5U6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1236518:AXF22 RS10110
gene id: 1236518:AXF22_RS10110
uniprot id: A0A1B1IAP3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1236518:AXF22 RS00985
gene id: 1236518:AXF22_RS00985
uniprot id: A0A1B1I5X8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS01300
gene id: 1236518:AXF22_RS01300
uniprot id: A0A1B1I637
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1236518:AXF22 RS03480
gene id: 1236518:AXF22_RS03480
uniprot id: A0A1B1I706
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS00145
gene id: 1236518:AXF22_RS00145
uniprot id: A0A1B1I902
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1236518:AXF22 RS09850
gene id: 1236518:AXF22_RS09850
uniprot id: A0A1B1IAH6
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS06640
gene id: 1236518:AXF22_RS06640
uniprot id: A0A1B1I8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1236518:AXF22 RS01550
gene id: 1236518:AXF22_RS01550
uniprot id: A0A1B1I611
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1236518:AXF22 RS02465
gene id: 1236518:AXF22_RS02465
uniprot id: A0A1B1I6M5
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS03470
gene id: 1236518:AXF22_RS03470
uniprot id: A0A1B1I717
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1236518:AXF22 RS00630
gene id: 1236518:AXF22_RS00630
uniprot id: A0A1B1I5N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1236518:AXF22 RS08650
gene id: 1236518:AXF22_RS08650
uniprot id: A0A1B1I9Y8
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS01680
gene id: 1236518:AXF22_RS01680
uniprot id: A0A1B1I643
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1236518:AXF22 RS00270
gene id: 1236518:AXF22_RS00270
uniprot id: A0A1B1I5F4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS02195
gene id: 1236518:AXF22_RS02195
uniprot id: A0A1B1I6C6
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS01735
gene id: 1236518:AXF22_RS01735
uniprot id: A0A1B1I916
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS05125
gene id: 1236518:AXF22_RS05125
uniprot id: A0A1B1I7G3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1236518:AXF22 RS00875
gene id: 1236518:AXF22_RS00875
uniprot id: A0A1B1I5V6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1236518:AXF22 RS12100
gene id: 1236518:AXF22_RS12100
uniprot id: A0A1B1IBG8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1236518:AXF22 RS07370
gene id: 1236518:AXF22_RS07370
uniprot id: A0A1B1I913
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1236518:AXF22 RS00830
gene id: 1236518:AXF22_RS00830
uniprot id: A0A1B1I5Q5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1236518:AXF22 RS12245
gene id: 1236518:AXF22_RS12245
uniprot id: A0A1B1IBK6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1236518:AXF22 RS10025
gene id: 1236518:AXF22_RS10025
uniprot id: A0A1B1IAH7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1236518:AXF22 RS08205
gene id: 1236518:AXF22_RS08205
uniprot id: A0A1B1I9R7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS12800
gene id: 1236518:AXF22_RS12800
uniprot id: A0A1B1IC31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1236518:AXF22 RS05320
gene id: 1236518:AXF22_RS05320
uniprot id: A0A1B1I7V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1236518:AXF22 RS04820
gene id: 1236518:AXF22_RS04820
uniprot id: A0A1B1I7N5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1236518:AXF22 RS00695
gene id: 1236518:AXF22_RS00695
uniprot id: A0A1B1I5P3
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1236518:AXF22 RS01170
gene id: 1236518:AXF22_RS01170
uniprot id: A0A1B1I5W7
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS08190
gene id: 1236518:AXF22_RS08190
uniprot id: A0A1B1I9N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1236518:AXF22 RS05200
gene id: 1236518:AXF22_RS05200
uniprot id: A0A1B1I7Y3
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS06660
gene id: 1236518:AXF22_RS06660
uniprot id: A0A1B1I8I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1236518:AXF22 RS01910
gene id: 1236518:AXF22_RS01910
uniprot id: A0A1B1I694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1236518:AXF22 RS06795
gene id: 1236518:AXF22_RS06795
uniprot id: A0A1B1I8R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1236518:AXF22 RS09645
gene id: 1236518:AXF22_RS09645
uniprot id: A0A1B1IAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1236518:AXF22 RS09255
gene id: 1236518:AXF22_RS09255
uniprot id: A0A1B1IAE4
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1236518:AXF22 RS01650
gene id: 1236518:AXF22_RS01650
uniprot id: A0A1B1I925
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS08060
gene id: 1236518:AXF22_RS08060
uniprot id: A0A1B1I9K8
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS09835
gene id: 1236518:AXF22_RS09835
uniprot id: A0A1B1IAD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1236518:AXF22 RS05450
gene id: 1236518:AXF22_RS05450
uniprot id: A0A1B1I7Y7
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS10780
gene id: 1236518:AXF22_RS10780
uniprot id: A0A1B1IAW2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1236518:AXF22 RS07215
gene id: 1236518:AXF22_RS07215
uniprot id: A0A1B1I8T2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1236518:AXF22 RS02670
gene id: 1236518:AXF22_RS02670
uniprot id: A0A1B1I6Q5
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

1236518:AXF22 RS04595
gene id: 1236518:AXF22_RS04595
uniprot id: A0A1B1I7I8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1236518:AXF22 RS06260
gene id: 1236518:AXF22_RS06260
uniprot id: A0A1B1I8D5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1236518:AXF22 RS08680
gene id: 1236518:AXF22_RS08680
uniprot id: A0A1B1I9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1236518:AXF22 RS10690
gene id: 1236518:AXF22_RS10690
uniprot id: A0A1B1IAZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1236518:AXF22 RS02475
gene id: 1236518:AXF22_RS02475
uniprot id: A0A1B1I6I0
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1236518:AXF22 RS08505
gene id: 1236518:AXF22_RS08505
uniprot id: A0A1B1I9S7
names: Similarity
messages: Belongs to the FBPase class 3 family.

1236518:AXF22 RS10105
gene id: 1236518:AXF22_RS10105
uniprot id: A0A1B1IAI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1236518:AXF22 RS00610
gene id: 1236518:AXF22_RS00610
uniprot id: A0A1B1I5L8
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS10340
gene id: 1236518:AXF22_RS10340
uniprot id: A0A1B1IAL7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1236518:AXF22 RS03355
gene id: 1236518:AXF22_RS03355
uniprot id: A0A1B1I724
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1236518:AXF22 RS06250
gene id: 1236518:AXF22_RS06250
uniprot id: A0A1B1I8H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1236518:AXF22 RS06375
gene id: 1236518:AXF22_RS06375
uniprot id: A0A1B1I8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1236518:AXF22 RS06905
gene id: 1236518:AXF22_RS06905
uniprot id: A0A1B1I8L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1236518:AXF22 RS11990
gene id: 1236518:AXF22_RS11990
uniprot id: A0A1B1IBF2
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1236518:AXF22 RS00565
gene id: 1236518:AXF22_RS00565
uniprot id: A0A1B1I5I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1236518:AXF22 RS00580
gene id: 1236518:AXF22_RS00580
uniprot id: A0A1B1I5J4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1236518:AXF22 RS00510
gene id: 1236518:AXF22_RS00510
uniprot id: A0A1B1I5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1236518:AXF22 RS04640
gene id: 1236518:AXF22_RS04640
uniprot id: A0A1B1I7K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1236518:AXF22 RS02920
gene id: 1236518:AXF22_RS02920
uniprot id: A0A1B1I6U6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1236518:AXF22 RS12860
gene id: 1236518:AXF22_RS12860
uniprot id: A0A1B1IBY2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1236518:AXF22 RS12485
gene id: 1236518:AXF22_RS12485
uniprot id: A0A1B1ICC0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1236518:AXF22 RS10845
gene id: 1236518:AXF22_RS10845
uniprot id: A0A1B1IAV4
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS01595
gene id: 1236518:AXF22_RS01595
uniprot id: A0A1B1I630
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1236518:AXF22 RS00535
gene id: 1236518:AXF22_RS00535
uniprot id: A0A1B1I5Q4
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS00465
gene id: 1236518:AXF22_RS00465
uniprot id: A0A1B1I5G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS09195
gene id: 1236518:AXF22_RS09195
uniprot id: A0A1B1IA82
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS01555
gene id: 1236518:AXF22_RS01555
uniprot id: A0A1B1I634
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1236518:AXF22 RS03580
gene id: 1236518:AXF22_RS03580
uniprot id: A0A1B1IBJ5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1236518:AXF22 RS04005
gene id: 1236518:AXF22_RS04005
uniprot id: A0A1B1I7A5
names: Similarity
messages: Belongs to the isochorismate synthase family.

1236518:AXF22 RS03145
gene id: 1236518:AXF22_RS03145
uniprot id: A0A1B1I6Z3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS00125
gene id: 1236518:AXF22_RS00125
uniprot id: A0A1B1I5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1236518:AXF22 RS12515
gene id: 1236518:AXF22_RS12515
uniprot id: A0A1B1IBY5
names: Similarity
messages: Belongs to the GARS family.

1236518:AXF22 RS03410
gene id: 1236518:AXF22_RS03410
uniprot id: A0A1B1I734
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1236518:AXF22 RS00300
gene id: 1236518:AXF22_RS00300
uniprot id: A0A1B1I5E1
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS08945
gene id: 1236518:AXF22_RS08945
uniprot id: A0A1B1IA01
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS02325
gene id: 1236518:AXF22_RS02325
uniprot id: A0A1B1I6F3
names: Similarity
messages: Belongs to the peptidase C69 family.

1236518:AXF22 RS01190
gene id: 1236518:AXF22_RS01190
uniprot id: A0A1B1I617
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1236518:AXF22 RS08810
gene id: 1236518:AXF22_RS08810
uniprot id: A0A1B1I9X6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1236518:AXF22 RS08315
gene id: 1236518:AXF22_RS08315
uniprot id: A0A1B1I9W9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1236518:AXF22 RS06325
gene id: 1236518:AXF22_RS06325
uniprot id: A0A1B1I8I0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS04475
gene id: 1236518:AXF22_RS04475
uniprot id: A0A1B1I7I3
names: Similarity
messages: Belongs to the RecJ family.

1236518:AXF22 RS06875
gene id: 1236518:AXF22_RS06875
uniprot id: A0A1B1I8L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1236518:AXF22 RS07615
gene id: 1236518:AXF22_RS07615
uniprot id: A0A1B1I9C8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1236518:AXF22 RS09640
gene id: 1236518:AXF22_RS09640
uniprot id: A0A1B1IAF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1236518:AXF22 RS12830
gene id: 1236518:AXF22_RS12830
uniprot id: A0A1B1IBZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1236518:AXF22 RS08040
gene id: 1236518:AXF22_RS08040
uniprot id: A0A1B1I9K1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1236518:AXF22 RS05520
gene id: 1236518:AXF22_RS05520
uniprot id: A0A1B1I811
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1236518:AXF22 RS05680
gene id: 1236518:AXF22_RS05680
uniprot id: A0A1B1I817
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1236518:AXF22 RS06370
gene id: 1236518:AXF22_RS06370
uniprot id: A0A1B1I8G0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1236518:AXF22 RS07555
gene id: 1236518:AXF22_RS07555
uniprot id: A0A1B1I9H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1236518:AXF22 RS04130
gene id: 1236518:AXF22_RS04130
uniprot id: A0A1B1I7C6
names: Subcellular Location Annotation
messages: Cytoplasm

1236518:AXF22 RS06890
gene id: 1236518:AXF22_RS06890
uniprot id: A0A1B1I8M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1236518:AXF22 RS01040
gene id: 1236518:AXF22_RS01040
uniprot id: A0A1B1I5Z1
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1236518:AXF22 RS12195
gene id: 1236518:AXF22_RS12195
uniprot id: A0A1B1IBL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1236518:AXF22 RS00545
gene id: 1236518:AXF22_RS00545
uniprot id: A0A1B1I5K4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1236518:AXF22 RS10405
gene id: 1236518:AXF22_RS10405
uniprot id: A0A1B1IAM8
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS12190
gene id: 1236518:AXF22_RS12190
uniprot id: A0A1B1IBJ7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1236518:AXF22 RS04035
gene id: 1236518:AXF22_RS04035
uniprot id: A0A1B1I7A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1236518:AXF22 RS05285
gene id: 1236518:AXF22_RS05285
uniprot id: A0A1B1I809
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1236518:AXF22 RS00030
gene id: 1236518:AXF22_RS00030
uniprot id: A0A1B1I5C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1236518:AXF22 RS05205
gene id: 1236518:AXF22_RS05205
uniprot id: A0A1B1I7U1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1236518:AXF22 RS06725
gene id: 1236518:AXF22_RS06725
uniprot id: A0A1B1I8L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1236518:AXF22 RS11680
gene id: 1236518:AXF22_RS11680
uniprot id: A0A1B1IBG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1236518:AXF22 RS01050
gene id: 1236518:AXF22_RS01050
uniprot id: A0A1B1I5V0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1236518:AXF22 RS12325
gene id: 1236518:AXF22_RS12325
uniprot id: A0A1B1IBM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1236518:AXF22 RS06355
gene id: 1236518:AXF22_RS06355
uniprot id: A0A1B1I8J7
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS09410
gene id: 1236518:AXF22_RS09410
uniprot id: A0A1B1IAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS08140
gene id: 1236518:AXF22_RS08140
uniprot id: A0A1B1IC17
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS01405
gene id: 1236518:AXF22_RS01405
uniprot id: A0A1B1I609
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1236518:AXF22 RS05660
gene id: 1236518:AXF22_RS05660
uniprot id: A0A1B1I844
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS12240
gene id: 1236518:AXF22_RS12240
uniprot id: A0A1B1IBU3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS04020
gene id: 1236518:AXF22_RS04020
uniprot id: A0A1B1I7C9
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1236518:AXF22 RS03125
gene id: 1236518:AXF22_RS03125
uniprot id: A0A1B1I6U9
names: Similarity
messages: Belongs to the CvfB family.

1236518:AXF22 RS01510
gene id: 1236518:AXF22_RS01510
uniprot id: A0A1B1I674
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS12300
gene id: 1236518:AXF22_RS12300
uniprot id: A0A1B1IBN0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1236518:AXF22 RS00140
gene id: 1236518:AXF22_RS00140
uniprot id: A0A1B1I5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS11450
gene id: 1236518:AXF22_RS11450
uniprot id: A0A1B1IB73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1236518:AXF22 RS01215
gene id: 1236518:AXF22_RS01215
uniprot id: A0A1B1I5W2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1236518:AXF22 RS12980
gene id: 1236518:AXF22_RS12980
uniprot id: A0A1B1IC37
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1236518:AXF22 RS04855
gene id: 1236518:AXF22_RS04855
uniprot id: A0A1B1I7Q1
names: Similarity
messages: Belongs to the CarB family.

1236518:AXF22 RS09460
gene id: 1236518:AXF22_RS09460
uniprot id: A0A1B1IA86
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1236518:AXF22 RS07675
gene id: 1236518:AXF22_RS07675
uniprot id: A0A1B1I9D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1236518:AXF22 RS07805
gene id: 1236518:AXF22_RS07805
uniprot id: A0A1B1I9G1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1236518:AXF22 RS10500
gene id: 1236518:AXF22_RS10500
uniprot id: A0A1B1IAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS04055
gene id: 1236518:AXF22_RS04055
uniprot id: A0A1B1I7B5
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS03370
gene id: 1236518:AXF22_RS03370
uniprot id: A0A1B1I6Y7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1236518:AXF22 RS07560
gene id: 1236518:AXF22_RS07560
uniprot id: A0A1B1I9C1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1236518:AXF22 RS08835
gene id: 1236518:AXF22_RS08835
uniprot id: A0A1B1I9Y5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1236518:AXF22 RS07585
gene id: 1236518:AXF22_RS07585
uniprot id: A0A1B1I9F9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1236518:AXF22 RS07345
gene id: 1236518:AXF22_RS07345
uniprot id: A0A1B1I8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1236518:AXF22 RS07260
gene id: 1236518:AXF22_RS07260
uniprot id: A0A1B1I8T6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1236518:AXF22 RS10890
gene id: 1236518:AXF22_RS10890
uniprot id: A0A1B1IAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS11555
gene id: 1236518:AXF22_RS11555
uniprot id: A0A1B1IB97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1236518:AXF22 RS11580
gene id: 1236518:AXF22_RS11580
uniprot id: A0A1B1IBB9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS00260
gene id: 1236518:AXF22_RS00260
uniprot id: A0A1B1I5J7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS08020
gene id: 1236518:AXF22_RS08020
uniprot id: A0A1B1I9P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1236518:AXF22 RS03945
gene id: 1236518:AXF22_RS03945
uniprot id: A0A1B1I795
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1236518:AXF22 RS00645
gene id: 1236518:AXF22_RS00645
uniprot id: A0A1B1I5S4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1236518:AXF22 RS01375
gene id: 1236518:AXF22_RS01375
uniprot id: A0A1B1I5Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS02590
gene id: 1236518:AXF22_RS02590
uniprot id: A0A1B1I6J7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS06505
gene id: 1236518:AXF22_RS06505
uniprot id: A0A1B1I8F7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1236518:AXF22 RS06775
gene id: 1236518:AXF22_RS06775
uniprot id: A0A1B1I8K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1236518:AXF22 RS09090
gene id: 1236518:AXF22_RS09090
uniprot id: A0A1B1IAB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1236518:AXF22 RS12970
gene id: 1236518:AXF22_RS12970
uniprot id: A0A1B1IBZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1236518:AXF22 RS02290
gene id: 1236518:AXF22_RS02290
uniprot id: A0A1B1I6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1236518:AXF22 RS04165
gene id: 1236518:AXF22_RS04165
uniprot id: A0A1B1I7B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1236518:AXF22 RS03950
gene id: 1236518:AXF22_RS03950
uniprot id: A0A1B1I794
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1236518:AXF22 RS01685
gene id: 1236518:AXF22_RS01685
uniprot id: A0A1B1I6A4
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS07000
gene id: 1236518:AXF22_RS07000
uniprot id: A0A1B1I8R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1236518:AXF22 RS06560
gene id: 1236518:AXF22_RS06560
uniprot id: A0A1B1I8M7
names: Similarity
messages: Belongs to the peptidase M16 family.

1236518:AXF22 RS11985
gene id: 1236518:AXF22_RS11985
uniprot id: A0A1B1IBG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1236518:AXF22 RS05600
gene id: 1236518:AXF22_RS05600
uniprot id: A0A1B1I805
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1236518:AXF22 RS04900
gene id: 1236518:AXF22_RS04900
uniprot id: A0A1B1I7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1236518:AXF22 RS08325
gene id: 1236518:AXF22_RS08325
uniprot id: A0A1B1I9T5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1236518:AXF22 RS01380
gene id: 1236518:AXF22_RS01380
uniprot id: A0A1B1I974
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1236518:AXF22 RS00285
gene id: 1236518:AXF22_RS00285
uniprot id: A0A1B1I5G7
names: Similarity
messages: Belongs to the YicC/YloC family.

1236518:AXF22 RS10350
gene id: 1236518:AXF22_RS10350
uniprot id: A0A1B1ICE3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1236518:AXF22 RS07855
gene id: 1236518:AXF22_RS07855
uniprot id: A0A1B1I9H0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1236518:AXF22 RS06395
gene id: 1236518:AXF22_RS06395
uniprot id: A0A1B1I997
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1236518:AXF22 RS06945
gene id: 1236518:AXF22_RS06945
uniprot id: A0A1B1I8N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1236518:AXF22 RS12795
gene id: 1236518:AXF22_RS12795
uniprot id: A0A1B1IBZ5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1236518:AXF22 RS06990
gene id: 1236518:AXF22_RS06990
uniprot id: A0A1B1I8P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1236518:AXF22 RS02110
gene id: 1236518:AXF22_RS02110
uniprot id: A0A1B1I6B5
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS12985
gene id: 1236518:AXF22_RS12985
uniprot id: A0A1B1IC13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1236518:AXF22 RS05225
gene id: 1236518:AXF22_RS05225
uniprot id: A0A1B1I7V9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS11610
gene id: 1236518:AXF22_RS11610
uniprot id: A0A1B1IB98
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1236518:AXF22 RS05175
gene id: 1236518:AXF22_RS05175
uniprot id: A0A1B1I7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1236518:AXF22 RS01660
gene id: 1236518:AXF22_RS01660
uniprot id: A0A1B1I633
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS12605
gene id: 1236518:AXF22_RS12605
uniprot id: A0A1B1IBS1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1236518:AXF22 RS05510
gene id: 1236518:AXF22_RS05510
uniprot id: A0A1B1I804
names: Similarity
messages: Belongs to the peptidase S41A family.

1236518:AXF22 RS00860
gene id: 1236518:AXF22_RS00860
uniprot id: A0A1B1I5S2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS03090
gene id: 1236518:AXF22_RS03090
uniprot id: A0A1B1I6T5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS08710
gene id: 1236518:AXF22_RS08710
uniprot id: A0A1B1IA31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1236518:AXF22 RS02225
gene id: 1236518:AXF22_RS02225
uniprot id: A0A1B1I6F8
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS00925
gene id: 1236518:AXF22_RS00925
uniprot id: A0A1B1I5X1
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS00615
gene id: 1236518:AXF22_RS00615
uniprot id: A0A1B1I5S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS06080
gene id: 1236518:AXF22_RS06080
uniprot id: A0A1B1I894
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS03020
gene id: 1236518:AXF22_RS03020
uniprot id: A0A1B1I6S8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1236518:AXF22 RS01175
gene id: 1236518:AXF22_RS01175
uniprot id: A0A1B1I914
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS02965
gene id: 1236518:AXF22_RS02965
uniprot id: A0A1B1I6S0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1236518:AXF22 RS12235
gene id: 1236518:AXF22_RS12235
uniprot id: A0A1B1IBP6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS11500
gene id: 1236518:AXF22_RS11500
uniprot id: A0A1B1IB79
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

1236518:AXF22 RS12680
gene id: 1236518:AXF22_RS12680
uniprot id: A0A1B1IC16
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1236518:AXF22 RS01765
gene id: 1236518:AXF22_RS01765
uniprot id: A0A1B1I669
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1236518:AXF22 RS02870
gene id: 1236518:AXF22_RS02870
uniprot id: A0A1B1I6R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1236518:AXF22 RS08120
gene id: 1236518:AXF22_RS08120
uniprot id: A0A1B1I9L2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1236518:AXF22 RS09450
gene id: 1236518:AXF22_RS09450
uniprot id: A0A1B1IA81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1236518:AXF22 RS07325
gene id: 1236518:AXF22_RS07325
uniprot id: A0A1B1I8V0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1236518:AXF22 RS05670
gene id: 1236518:AXF22_RS05670
uniprot id: A0A1B1I860
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1236518:AXF22 RS01530
gene id: 1236518:AXF22_RS01530
uniprot id: A0A1B1I631
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1236518:AXF22 RS08795
gene id: 1236518:AXF22_RS08795
uniprot id: A0A1B1I9Z5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1236518:AXF22 RS06840
gene id: 1236518:AXF22_RS06840
uniprot id: A0A1B1I8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS11445
gene id: 1236518:AXF22_RS11445
uniprot id: A0A1B1IBG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1236518:AXF22 RS00485
gene id: 1236518:AXF22_RS00485
uniprot id: A0A1B1I5P4
names: Subcellular Location Annotation
messages: Cytoplasm

1236518:AXF22 RS12275
gene id: 1236518:AXF22_RS12275
uniprot id: A0A1B1IBL2
names: Similarity
messages: Belongs to the AIR synthase family.

1236518:AXF22 RS03465
gene id: 1236518:AXF22_RS03465
uniprot id: A0A1B1I744
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1236518:AXF22 RS03900
gene id: 1236518:AXF22_RS03900
uniprot id: A0A1B1I7B3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1236518:AXF22 RS03450
gene id: 1236518:AXF22_RS03450
uniprot id: A0A1B1I702
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1236518:AXF22 RS02820
gene id: 1236518:AXF22_RS02820
uniprot id: A0A1B1I6N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1236518:AXF22 RS06700
gene id: 1236518:AXF22_RS06700
uniprot id: A0A1B1I8P1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1236518:AXF22 RS02910
gene id: 1236518:AXF22_RS02910
uniprot id: A0A1B1I6P5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1236518:AXF22 RS10905
gene id: 1236518:AXF22_RS10905
uniprot id: A0A1B1IB29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1236518:AXF22 RS10765
gene id: 1236518:AXF22_RS10765
uniprot id: A0A1B1IAW0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1236518:AXF22 RS07515
gene id: 1236518:AXF22_RS07515
uniprot id: A0A1B1I939
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS12540
gene id: 1236518:AXF22_RS12540
uniprot id: A0A1B1IBT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1236518:AXF22 RS03395
gene id: 1236518:AXF22_RS03395
uniprot id: A0A1B1I6Z1
names: Similarity
messages: Belongs to the peptidase S13 family.

1236518:AXF22 RS07720
gene id: 1236518:AXF22_RS07720
uniprot id: A0A1B1I9K2
names: Similarity
messages: Belongs to the DapA family.

1236518:AXF22 RS11355
gene id: 1236518:AXF22_RS11355
uniprot id: A0A1B1IB78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1236518:AXF22 RS08215
gene id: 1236518:AXF22_RS08215
uniprot id: A0A1B1I9M9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1236518:AXF22 RS06515
gene id: 1236518:AXF22_RS06515
uniprot id: A0A1B1I8L3
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS01385
gene id: 1236518:AXF22_RS01385
uniprot id: A0A1B1I605
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS10725
gene id: 1236518:AXF22_RS10725
uniprot id: A0A1B1IAV2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1236518:AXF22 RS11945
gene id: 1236518:AXF22_RS11945
uniprot id: A0A1B1IBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS00905
gene id: 1236518:AXF22_RS00905
uniprot id: A0A1B1I5Q0
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS11670
gene id: 1236518:AXF22_RS11670
uniprot id: A0A1B1IBA2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1236518:AXF22 RS00480
gene id: 1236518:AXF22_RS00480
uniprot id: A0A1B1I5H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS11925
gene id: 1236518:AXF22_RS11925
uniprot id: A0A1B1IBJ5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1236518:AXF22 RS12920
gene id: 1236518:AXF22_RS12920
uniprot id: A0A1B1IBX2
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS07385
gene id: 1236518:AXF22_RS07385
uniprot id: A0A1B1I8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1236518:AXF22 RS01145
gene id: 1236518:AXF22_RS01145
uniprot id: A0A1B1I5V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1236518:AXF22 RS04685
gene id: 1236518:AXF22_RS04685
uniprot id: A0A1B1I7Q8
names: Caution
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS00325
gene id: 1236518:AXF22_RS00325
uniprot id: A0A1B1I5L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1236518:AXF22 RS00265
gene id: 1236518:AXF22_RS00265
uniprot id: A0A1B1I5G3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1236518:AXF22 RS02730
gene id: 1236518:AXF22_RS02730
uniprot id: A0A1B1I6Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1236518:AXF22 RS08490
gene id: 1236518:AXF22_RS08490
uniprot id: A0A1B1I9R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1236518:AXF22 RS12095
gene id: 1236518:AXF22_RS12095
uniprot id: A0A1B1IBJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1236518:AXF22 RS06150
gene id: 1236518:AXF22_RS06150
uniprot id: A0A1B1I8F1
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS12910
gene id: 1236518:AXF22_RS12910
uniprot id: A0A1B1IBY3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1236518:AXF22 RS02805
gene id: 1236518:AXF22_RS02805
uniprot id: A0A1B1I6P8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

1236518:AXF22 RS02720
gene id: 1236518:AXF22_RS02720
uniprot id: A0A1B1I6M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1236518:AXF22 RS06665
gene id: 1236518:AXF22_RS06665
uniprot id: A0A1B1I8I8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1236518:AXF22 RS02710
gene id: 1236518:AXF22_RS02710
uniprot id: A0A1B1I6M7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1236518:AXF22 RS01705
gene id: 1236518:AXF22_RS01705
uniprot id: A0A1B1I660
names: Similarity
messages: Belongs to the SufE family.

1236518:AXF22 RS07480
gene id: 1236518:AXF22_RS07480
uniprot id: A0A1B1I931
names: Similarity
messages: Belongs to the UPF0102 family.

1236518:AXF22 RS00015
gene id: 1236518:AXF22_RS00015
uniprot id: A0A1B1I5B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1236518:AXF22 RS03385
gene id: 1236518:AXF22_RS03385
uniprot id: A0A1B1I6Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1236518:AXF22 RS08105
gene id: 1236518:AXF22_RS08105
uniprot id: A0A1B1I9P6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1236518:AXF22 RS07940
gene id: 1236518:AXF22_RS07940
uniprot id: A0A1B1I9I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1236518:AXF22 RS04840
gene id: 1236518:AXF22_RS04840
uniprot id: A0A1B1I7P1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS03930
gene id: 1236518:AXF22_RS03930
uniprot id: A0A1B1I767
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1236518:AXF22 RS12345
gene id: 1236518:AXF22_RS12345
uniprot id: A0A1B1IBM7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1236518:AXF22 RS11115
gene id: 1236518:AXF22_RS11115
uniprot id: A0A1B1IB21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1236518:AXF22 RS05430
gene id: 1236518:AXF22_RS05430
uniprot id: A0A1B1I820
names: Similarity
messages: Belongs to the peptidase S8 family.

1236518:AXF22 RS12090
gene id: 1236518:AXF22_RS12090
uniprot id: A0A1B1IBH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1236518:AXF22 RS08875
gene id: 1236518:AXF22_RS08875
uniprot id: A0A1B1IA67
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS12895
gene id: 1236518:AXF22_RS12895
uniprot id: A0A1B1IBY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1236518:AXF22 RS00665
gene id: 1236518:AXF22_RS00665
uniprot id: A0A1B1I5M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1236518:AXF22 RS09565
gene id: 1236518:AXF22_RS09565
uniprot id: A0A1B1IAC8
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1236518:AXF22 RS12875
gene id: 1236518:AXF22_RS12875
uniprot id: A0A1B1IC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1236518:AXF22 RS04090
gene id: 1236518:AXF22_RS04090
uniprot id: A0A1B1I7A9
names: Similarity
messages: Belongs to the NusB family.

1236518:AXF22 RS12165
gene id: 1236518:AXF22_RS12165
uniprot id: A0A1B1IBL6
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1236518:AXF22 RS05170
gene id: 1236518:AXF22_RS05170
uniprot id: A0A1B1I7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1236518:AXF22 RS06915
gene id: 1236518:AXF22_RS06915
uniprot id: A0A1B1I8M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1236518:AXF22 RS11710
gene id: 1236518:AXF22_RS11710
uniprot id: A0A1B1IBK7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1236518:AXF22 RS11410
gene id: 1236518:AXF22_RS11410
uniprot id: A0A1B1IB75
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS02245
gene id: 1236518:AXF22_RS02245
uniprot id: A0A1B1I6E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS08630
gene id: 1236518:AXF22_RS08630
uniprot id: A0A1B1I9T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1236518:AXF22 RS12110
gene id: 1236518:AXF22_RS12110
uniprot id: A0A1B1IBJ6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1236518:AXF22 RS12790
gene id: 1236518:AXF22_RS12790
uniprot id: A0A1B1IBX1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1236518:AXF22 RS00095
gene id: 1236518:AXF22_RS00095
uniprot id: A0A1B1I5D2
names: Similarity
messages: Belongs to the peptidase M24B family.

1236518:AXF22 RS04210
gene id: 1236518:AXF22_RS04210
uniprot id: A0A1B1I7G3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1236518:AXF22 RS04875
gene id: 1236518:AXF22_RS04875
uniprot id: A0A1B1I7N3
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1236518:AXF22 RS10465
gene id: 1236518:AXF22_RS10465
uniprot id: A0A1B1IAV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS06585
gene id: 1236518:AXF22_RS06585
uniprot id: A0A1B1I8G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS02685
gene id: 1236518:AXF22_RS02685
uniprot id: A0A1B1I932
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1236518:AXF22 RS12645
gene id: 1236518:AXF22_RS12645
uniprot id: A0A1B1IBY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS01930
gene id: 1236518:AXF22_RS01930
uniprot id: A0A1B1I6A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1236518:AXF22 RS06630
gene id: 1236518:AXF22_RS06630
uniprot id: A0A1B1I8K2
names: Similarity
messages: Belongs to the peptidase C10 family.

1236518:AXF22 RS01645
gene id: 1236518:AXF22_RS01645
uniprot id: A0A1B1I690
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS01970
gene id: 1236518:AXF22_RS01970
uniprot id: A0A1B1I686
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1236518:AXF22 RS10450
gene id: 1236518:AXF22_RS10450
uniprot id: A0A1B1IAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS08115
gene id: 1236518:AXF22_RS08115
uniprot id: A0A1B1I9R6
names: Similarity
messages: Belongs to the peptidase M13 family.

1236518:AXF22 RS09540
gene id: 1236518:AXF22_RS09540
uniprot id: A0A1B1IAC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1236518:AXF22 RS04850
gene id: 1236518:AXF22_RS04850
uniprot id: A0A1B1I7P6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1236518:AXF22 RS00250
gene id: 1236518:AXF22_RS00250
uniprot id: A0A1B1I5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1236518:AXF22 RS01295
gene id: 1236518:AXF22_RS01295
uniprot id: A0A1B1I5Z3
names: Similarity
messages: Belongs to the DapB family.

1236518:AXF22 RS04480
gene id: 1236518:AXF22_RS04480
uniprot id: A0A1B1I7G8
names: Similarity
messages: Belongs to the peptidase C1 family.

1236518:AXF22 RS06600
gene id: 1236518:AXF22_RS06600
uniprot id: A0A1B1I8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1236518:AXF22 RS00560
gene id: 1236518:AXF22_RS00560
uniprot id: A0A1B1I5L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1236518:AXF22 RS01075
gene id: 1236518:AXF22_RS01075
uniprot id: A0A1B1I5T6
names: Similarity
messages: Belongs to the glycosyl hydrolase 66 family.

1236518:AXF22 RS07010
gene id: 1236518:AXF22_RS07010
uniprot id: A0A1B1I8N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1236518:AXF22 RS05185
gene id: 1236518:AXF22_RS05185
uniprot id: A0A1B1I971
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1236518:AXF22 RS06810
gene id: 1236518:AXF22_RS06810
uniprot id: A0A1B1I8K0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1236518:AXF22 RS06960
gene id: 1236518:AXF22_RS06960
uniprot id: A0A1B1I8M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1236518:AXF22 RS06995
gene id: 1236518:AXF22_RS06995
uniprot id: A0A1B1I8P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1236518:AXF22 RS10875
gene id: 1236518:AXF22_RS10875
uniprot id: A0A1B1IB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS07090
gene id: 1236518:AXF22_RS07090
uniprot id: A0A1B1I8R1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1236518:AXF22 RS00240
gene id: 1236518:AXF22_RS00240
uniprot id: A0A1B1I5D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1236518:AXF22 RS13015
gene id: 1236518:AXF22_RS13015
uniprot id: A0A1B1IC75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS05975
gene id: 1236518:AXF22_RS05975
uniprot id: A0A1B1I8D2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1236518:AXF22 RS04400
gene id: 1236518:AXF22_RS04400
uniprot id: A0A1B1I7G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1236518:AXF22 RS03240
gene id: 1236518:AXF22_RS03240
uniprot id: A0A1B1I6X0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS04870
gene id: 1236518:AXF22_RS04870
uniprot id: A0A1B1I7T9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1236518:AXF22 RS00915
gene id: 1236518:AXF22_RS00915
uniprot id: A0A1B1I5Q7
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1236518:AXF22 RS06165
gene id: 1236518:AXF22_RS06165
uniprot id: A0A1B1I8A5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1236518:AXF22 RS01945
gene id: 1236518:AXF22_RS01945
uniprot id: A0A1B1I6E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1236518:AXF22 RS07595
gene id: 1236518:AXF22_RS07595
uniprot id: A0A1B1I9B8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1236518:AXF22 RS06500
gene id: 1236518:AXF22_RS06500
uniprot id: A0A1B1I9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1236518:AXF22 RS09610
gene id: 1236518:AXF22_RS09610
uniprot id: A0A1B1IAG0
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1236518:AXF22 RS13050
gene id: 1236518:AXF22_RS13050
uniprot id: A0A1B1ICA3
names: Similarity
messages: Belongs to the YoeB family.

1236518:AXF22 RS11280
gene id: 1236518:AXF22_RS11280
uniprot id: A0A1B1IB28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1236518:AXF22 RS07405
gene id: 1236518:AXF22_RS07405
uniprot id: A0A1B1I8V7
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS08340
gene id: 1236518:AXF22_RS08340
uniprot id: A0A1B1I9W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1236518:AXF22 RS11535
gene id: 1236518:AXF22_RS11535
uniprot id: A0A1B1IB89
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1236518:AXF22 RS08485
gene id: 1236518:AXF22_RS08485
uniprot id: A0A1B1IC26
names: Similarity
messages: Belongs to the aspartokinase family.

1236518:AXF22 RS00685
gene id: 1236518:AXF22_RS00685
uniprot id: A0A1B1I5K7
names: Similarity
messages: Belongs to the peptidase S41A family.

1236518:AXF22 RS02235
gene id: 1236518:AXF22_RS02235
uniprot id: A0A1B1I6F4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1236518:AXF22 RS05050
gene id: 1236518:AXF22_RS05050
uniprot id: A0A1B1I7R3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1236518:AXF22 RS06715
gene id: 1236518:AXF22_RS06715
uniprot id: A0A1B1I8J2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1236518:AXF22 RS00730
gene id: 1236518:AXF22_RS00730
uniprot id: A0A1B1I5U3
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS06910
gene id: 1236518:AXF22_RS06910
uniprot id: A0A1B1I8Q1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1236518:AXF22 RS12815
gene id: 1236518:AXF22_RS12815
uniprot id: A0A1B1IBU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1236518:AXF22 RS02930
gene id: 1236518:AXF22_RS02930
uniprot id: A0A1B1I6S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1236518:AXF22 RS06265
gene id: 1236518:AXF22_RS06265
uniprot id: A0A1B1I8B9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1236518:AXF22 RS05290
gene id: 1236518:AXF22_RS05290
uniprot id: A0A1B1I7W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1236518:AXF22 RS08620
gene id: 1236518:AXF22_RS08620
uniprot id: A0A1B1I9U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1236518:AXF22 RS12640
gene id: 1236518:AXF22_RS12640
uniprot id: A0A1B1IBR7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS11980
gene id: 1236518:AXF22_RS11980
uniprot id: A0A1B1IBF5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1236518:AXF22 RS08350
gene id: 1236518:AXF22_RS08350
uniprot id: A0A1B1I9S4
names: Similarity
messages: Belongs to the peptidase M16 family.

1236518:AXF22 RS00805
gene id: 1236518:AXF22_RS00805
uniprot id: A0A1B1I5R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS01115
gene id: 1236518:AXF22_RS01115
uniprot id: A0A1B1I5W1
names: Similarity
messages: Belongs to the peptidase S41A family.

1236518:AXF22 RS06970
gene id: 1236518:AXF22_RS06970
uniprot id: A0A1B1I8N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1236518:AXF22 RS06670
gene id: 1236518:AXF22_RS06670
uniprot id: A0A1B1I8K1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1236518:AXF22 RS00705
gene id: 1236518:AXF22_RS00705
uniprot id: A0A1B1I5L5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS02915
gene id: 1236518:AXF22_RS02915
uniprot id: A0A1B1I6Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1236518:AXF22 RS03155
gene id: 1236518:AXF22_RS03155
uniprot id: A0A1B1I6W2
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1236518:AXF22 RS05230
gene id: 1236518:AXF22_RS05230
uniprot id: A0A1B1I7Z5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1236518:AXF22 RS07465
gene id: 1236518:AXF22_RS07465
uniprot id: A0A1B1I912
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS07925
gene id: 1236518:AXF22_RS07925
uniprot id: A0A1B1I9I1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1236518:AXF22 RS01505
gene id: 1236518:AXF22_RS01505
uniprot id: A0A1B1I614
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1236518:AXF22 RS11285
gene id: 1236518:AXF22_RS11285
uniprot id: A0A1B1IBA3
names: Similarity
messages: Belongs to the peptidase S9C family.

1236518:AXF22 RS07780
gene id: 1236518:AXF22_RS07780
uniprot id: A0A1B1I9F6
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS04690
gene id: 1236518:AXF22_RS04690
uniprot id: A0A1B1I7L7
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS04590
gene id: 1236518:AXF22_RS04590
uniprot id: A0A1B1I7K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1236518:AXF22 RS06160
gene id: 1236518:AXF22_RS06160
uniprot id: A0A1B1I8A4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1236518:AXF22 RS12560
gene id: 1236518:AXF22_RS12560
uniprot id: A0A1B1IBV7
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS10700
gene id: 1236518:AXF22_RS10700
uniprot id: A0A1B1IAW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1236518:AXF22 RS11005
gene id: 1236518:AXF22_RS11005
uniprot id: A0A1B1IAY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1236518:AXF22 RS00190
gene id: 1236518:AXF22_RS00190
uniprot id: A0A1B1I5F3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1236518:AXF22 RS09220
gene id: 1236518:AXF22_RS09220
uniprot id: A0A1B1IA43
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS00620
gene id: 1236518:AXF22_RS00620
uniprot id: A0A1B1I5M3
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS06130
gene id: 1236518:AXF22_RS06130
uniprot id: A0A1B1I8F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1236518:AXF22 RS00385
gene id: 1236518:AXF22_RS00385
uniprot id: A0A1B1I5I3
names: Similarity
messages: Belongs to the peptidase M13 family.

1236518:AXF22 RS00020
gene id: 1236518:AXF22_RS00020
uniprot id: A0A1B1I5C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1236518:AXF22 RS03460
gene id: 1236518:AXF22_RS03460
uniprot id: A0A1B1I700
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1236518:AXF22 RS05630
gene id: 1236518:AXF22_RS05630
uniprot id: A0A1B1I814
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS01995
gene id: 1236518:AXF22_RS01995
uniprot id: A0A1B1I6A8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1236518:AXF22 RS04355
gene id: 1236518:AXF22_RS04355
uniprot id: A0A1B1I7E7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1236518:AXF22 RS02515
gene id: 1236518:AXF22_RS02515
uniprot id: A0A1B1I6K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1236518:AXF22 RS04865
gene id: 1236518:AXF22_RS04865
uniprot id: A0A1B1I970
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS11060
gene id: 1236518:AXF22_RS11060
uniprot id: A0A1B1IB09
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS05105
gene id: 1236518:AXF22_RS05105
uniprot id: A0A1B1I7T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1236518:AXF22 RS06900
gene id: 1236518:AXF22_RS06900
uniprot id: A0A1B1I8T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1236518:AXF22 RS03920
gene id: 1236518:AXF22_RS03920
uniprot id: A0A1B1I784
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS02650
gene id: 1236518:AXF22_RS02650
uniprot id: A0A1B1I6L0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1236518:AXF22 RS07335
gene id: 1236518:AXF22_RS07335
uniprot id: A0A1B1I8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1236518:AXF22 RS09880
gene id: 1236518:AXF22_RS09880
uniprot id: A0A1B1IAG2
names: Similarity
messages: Belongs to the peptidase C10 family.

1236518:AXF22 RS05055
gene id: 1236518:AXF22_RS05055
uniprot id: A0A1B1I7S1
names: Similarity
messages: Belongs to the peptidase S49 family.

1236518:AXF22 RS09200
gene id: 1236518:AXF22_RS09200
uniprot id: A0A1B1IC78
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS03220
gene id: 1236518:AXF22_RS03220
uniprot id: A0A1B1I704
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1236518:AXF22 RS04795
gene id: 1236518:AXF22_RS04795
uniprot id: A0A1B1I7N4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1236518:AXF22 RS04570
gene id: 1236518:AXF22_RS04570
uniprot id: A0A1B1I7I7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1236518:AXF22 RS02510
gene id: 1236518:AXF22_RS02510
uniprot id: A0A1B1I6K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1236518:AXF22 RS09225
gene id: 1236518:AXF22_RS09225
uniprot id: A0A1B1IA84
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS01600
gene id: 1236518:AXF22_RS01600
uniprot id: A0A1B1I624
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1236518:AXF22 RS01590
gene id: 1236518:AXF22_RS01590
uniprot id: A0A1B1I683
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1236518:AXF22 RS09530
gene id: 1236518:AXF22_RS09530
uniprot id: A0A1B1IAJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1236518:AXF22 RS12430
gene id: 1236518:AXF22_RS12430
uniprot id: A0A1B1IBU4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1236518:AXF22 RS10595
gene id: 1236518:AXF22_RS10595
uniprot id: A0A1B1IAS1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

1236518:AXF22 RS07830
gene id: 1236518:AXF22_RS07830
uniprot id: A0A1B1I9G6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1236518:AXF22 RS12265
gene id: 1236518:AXF22_RS12265
uniprot id: A0A1B1IBN1
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1236518:AXF22 RS08080
gene id: 1236518:AXF22_RS08080
uniprot id: A0A1B1I9Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1236518:AXF22 RS03975
gene id: 1236518:AXF22_RS03975
uniprot id: A0A1B1I791
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1236518:AXF22 RS11150
gene id: 1236518:AXF22_RS11150
uniprot id: A0A1B1IB72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1236518:AXF22 RS11950
gene id: 1236518:AXF22_RS11950
uniprot id: A0A1B1IBG4
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS05470
gene id: 1236518:AXF22_RS05470
uniprot id: A0A1B1I808
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS07030
gene id: 1236518:AXF22_RS07030
uniprot id: A0A1B1I8P8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1236518:AXF22 RS04315
gene id: 1236518:AXF22_RS04315
uniprot id: A0A1B1I7I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1236518:AXF22 RS07005
gene id: 1236518:AXF22_RS07005
uniprot id: A0A1B1I8V2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1236518:AXF22 RS05620
gene id: 1236518:AXF22_RS05620
uniprot id: A0A1B1I849
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1236518:AXF22 RS01965
gene id: 1236518:AXF22_RS01965
uniprot id: A0A1B1I6A3
names: Similarity
messages: Belongs to the Skp family.

1236518:AXF22 RS00045
gene id: 1236518:AXF22_RS00045
uniprot id: A0A1B1I5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1236518:AXF22 RS12270
gene id: 1236518:AXF22_RS12270
uniprot id: A0A1B1IBN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1236518:AXF22 RS01990
gene id: 1236518:AXF22_RS01990
uniprot id: A0A1B1I6B0
names: Similarity
messages: Belongs to the UPF0145 family.

1236518:AXF22 RS10775
gene id: 1236518:AXF22_RS10775
uniprot id: A0A1B1IB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1236518:AXF22 RS03270
gene id: 1236518:AXF22_RS03270
uniprot id: A0A1B1I6W8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1236518:AXF22 RS05605
gene id: 1236518:AXF22_RS05605
uniprot id: A0A1B1I833
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1236518:AXF22 RS04265
gene id: 1236518:AXF22_RS04265
uniprot id: A0A1B1I7G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1236518:AXF22 RS00010
gene id: 1236518:AXF22_RS00010
uniprot id: A0A1B1I5C1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1236518:AXF22 RS07305
gene id: 1236518:AXF22_RS07305
uniprot id: A0A1B1I8X8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1236518:AXF22 RS07225
gene id: 1236518:AXF22_RS07225
uniprot id: A0A1B1I8V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1236518:AXF22 RS01670
gene id: 1236518:AXF22_RS01670
uniprot id: A0A1B1I636
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS04645
gene id: 1236518:AXF22_RS04645
uniprot id: A0A1B1I7L5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS02600
gene id: 1236518:AXF22_RS02600
uniprot id: A0A1B1I6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1236518:AXF22 RS05655
gene id: 1236518:AXF22_RS05655
uniprot id: A0A1B1I815
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1236518:AXF22 RS07015
gene id: 1236518:AXF22_RS07015
uniprot id: A0A1B1I8S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1236518:AXF22 RS03825
gene id: 1236518:AXF22_RS03825
uniprot id: A0A1B1I798
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1236518:AXF22 RS02880
gene id: 1236518:AXF22_RS02880
uniprot id: A0A1B1I936
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS00800
gene id: 1236518:AXF22_RS00800
uniprot id: A0A1B1I5M7
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS03245
gene id: 1236518:AXF22_RS03245
uniprot id: A0A1B1I6Z7
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS11310
gene id: 1236518:AXF22_RS11310
uniprot id: A0A1B1IB44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1236518:AXF22 RS01960
gene id: 1236518:AXF22_RS01960
uniprot id: A0A1B1I685
names: Similarity
messages: Belongs to the Skp family.

1236518:AXF22 RS10760
gene id: 1236518:AXF22_RS10760
uniprot id: A0A1B1IAV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1236518:AXF22 RS03775
gene id: 1236518:AXF22_RS03775
uniprot id: A0A1B1I766
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1236518:AXF22 RS11325
gene id: 1236518:AXF22_RS11325
uniprot id: A0A1B1IBD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1236518:AXF22 RS05480
gene id: 1236518:AXF22_RS05480
uniprot id: A0A1B1I832
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1236518:AXF22 RS11465
gene id: 1236518:AXF22_RS11465
uniprot id: A0A1B1IBD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1236518:AXF22 RS12405
gene id: 1236518:AXF22_RS12405
uniprot id: A0A1B1IBS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1236518:AXF22 RS12475
gene id: 1236518:AXF22_RS12475
uniprot id: A0A1B1IBN7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS05455
gene id: 1236518:AXF22_RS05455
uniprot id: A0A1B1I802
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1236518:AXF22 RS01220
gene id: 1236518:AXF22_RS01220
uniprot id: A0A1B1I619
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1236518:AXF22 RS07430
gene id: 1236518:AXF22_RS07430
uniprot id: A0A1B1I8Y2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1236518:AXF22 RS11545
gene id: 1236518:AXF22_RS11545
uniprot id: A0A1B1IBH9
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS06925
gene id: 1236518:AXF22_RS06925
uniprot id: A0A1B1I8M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1236518:AXF22 RS11275
gene id: 1236518:AXF22_RS11275
uniprot id: A0A1B1IB47
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS12590
gene id: 1236518:AXF22_RS12590
uniprot id: A0A1B1IBX4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1236518:AXF22 RS06155
gene id: 1236518:AXF22_RS06155
uniprot id: A0A1B1I899
names: Similarity
messages: Belongs to the DEAD box helicase family.

1236518:AXF22 RS03855
gene id: 1236518:AXF22_RS03855
uniprot id: A0A1B1I759
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1236518:AXF22 RS02220
gene id: 1236518:AXF22_RS02220
uniprot id: A0A1B1I6J1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1236518:AXF22 RS12000
gene id: 1236518:AXF22_RS12000
uniprot id: A0A1B1IBH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1236518:AXF22 RS06335
gene id: 1236518:AXF22_RS06335
uniprot id: A0A1B1I8D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1236518:AXF22 RS09600
gene id: 1236518:AXF22_RS09600
uniprot id: A0A1B1IAD5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS12885
gene id: 1236518:AXF22_RS12885
uniprot id: A0A1B1IC02
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1236518:AXF22 RS09925
gene id: 1236518:AXF22_RS09925
uniprot id: A0A1B1IAG1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS00395
gene id: 1236518:AXF22_RS00395
uniprot id: A0A1B1I5I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1236518:AXF22 RS12340
gene id: 1236518:AXF22_RS12340
uniprot id: A0A1B1IBV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1236518:AXF22 RS05580
gene id: 1236518:AXF22_RS05580
uniprot id: A0A1B1I813
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1236518:AXF22 RS00650
gene id: 1236518:AXF22_RS00650
uniprot id: A0A1B1I5N0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1236518:AXF22 RS02785
gene id: 1236518:AXF22_RS02785
uniprot id: A0A1B1I6P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1236518:AXF22 RS00515
gene id: 1236518:AXF22_RS00515
uniprot id: A0A1B1I5H8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1236518:AXF22 RS06930
gene id: 1236518:AXF22_RS06930
uniprot id: A0A1B1I8N7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1236518:AXF22 RS09405
gene id: 1236518:AXF22_RS09405
uniprot id: A0A1B1IAC3
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS11515
gene id: 1236518:AXF22_RS11515
uniprot id: A0A1B1IBE0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

1236518:AXF22 RS02850
gene id: 1236518:AXF22_RS02850
uniprot id: A0A1B1I6Q1
names: Similarity
messages: Belongs to the UPF0758 family.

1236518:AXF22 RS02760
gene id: 1236518:AXF22_RS02760
uniprot id: A0A1B1I6S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1236518:AXF22 RS01360
gene id: 1236518:AXF22_RS01360
uniprot id: A0A1B1I941
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS09740
gene id: 1236518:AXF22_RS09740
uniprot id: A0A1B1IAD4
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS02970
gene id: 1236518:AXF22_RS02970
uniprot id: A0A1B1I6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1236518:AXF22 RS12685
gene id: 1236518:AXF22_RS12685
uniprot id: A0A1B1IBT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS08220
gene id: 1236518:AXF22_RS08220
uniprot id: A0A1B1I9R5
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1236518:AXF22 RS00910
gene id: 1236518:AXF22_RS00910
uniprot id: A0A1B1I5T2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1236518:AXF22 RS01440
gene id: 1236518:AXF22_RS01440
uniprot id: A0A1B1I615
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1236518:AXF22 RS10560
gene id: 1236518:AXF22_RS10560
uniprot id: A0A1B1IAS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1236518:AXF22 RS07880
gene id: 1236518:AXF22_RS07880
uniprot id: A0A1B1I9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1236518:AXF22 RS09690
gene id: 1236518:AXF22_RS09690
uniprot id: A0A1B1IAB8
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS08770
gene id: 1236518:AXF22_RS08770
uniprot id: A0A1B1I9X0
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1236518:AXF22 RS07775
gene id: 1236518:AXF22_RS07775
uniprot id: A0A1B1I9F5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1236518:AXF22 RS02405
gene id: 1236518:AXF22_RS02405
uniprot id: A0A1B1I6H0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS08070
gene id: 1236518:AXF22_RS08070
uniprot id: A0A1B1IC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1236518:AXF22 RS09580
gene id: 1236518:AXF22_RS09580
uniprot id: A0A1B1IAE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS02125
gene id: 1236518:AXF22_RS02125
uniprot id: A0A1B1I6C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1236518:AXF22 RS11505
gene id: 1236518:AXF22_RS11505
uniprot id: A0A1B1IB90
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

1236518:AXF22 RS05720
gene id: 1236518:AXF22_RS05720
uniprot id: A0A1B1I875
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1236518:AXF22 RS02900
gene id: 1236518:AXF22_RS02900
uniprot id: A0A1B1I6R0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1236518:AXF22 RS09620
gene id: 1236518:AXF22_RS09620
uniprot id: A0A1B1IAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1236518:AXF22 RS04660
gene id: 1236518:AXF22_RS04660
uniprot id: A0A1B1I7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1236518:AXF22 RS12375
gene id: 1236518:AXF22_RS12375
uniprot id: A0A1B1IBQ8
names: Similarity
messages: Belongs to the Skp family.

1236518:AXF22 RS01465
gene id: 1236518:AXF22_RS01465
uniprot id: A0A1B1I618
names: Similarity
messages: Belongs to the sigma-54 factor family.

1236518:AXF22 RS00890
gene id: 1236518:AXF22_RS00890
uniprot id: A0A1B1I5R7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1236518:AXF22 RS05595
gene id: 1236518:AXF22_RS05595
uniprot id: A0A1B1I859
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1236518:AXF22 RS06520
gene id: 1236518:AXF22_RS06520
uniprot id: A0A1B1I8F4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1236518:AXF22 RS07200
gene id: 1236518:AXF22_RS07200
uniprot id: A0A1B1I8S5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1236518:AXF22 RS00115
gene id: 1236518:AXF22_RS00115
uniprot id: A0A1B1I5D5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1236518:AXF22 RS12280
gene id: 1236518:AXF22_RS12280
uniprot id: A0A1B1IBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1236518:AXF22 RS12335
gene id: 1236518:AXF22_RS12335
uniprot id: A0A1B1IBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1236518:AXF22 RS06190
gene id: 1236518:AXF22_RS06190
uniprot id: A0A1B1I8C0
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS05685
gene id: 1236518:AXF22_RS05685
uniprot id: A0A1B1I830
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

1236518:AXF22 RS05505
gene id: 1236518:AXF22_RS05505
uniprot id: A0A1B1I9E8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1236518:AXF22 RS10885
gene id: 1236518:AXF22_RS10885
uniprot id: A0A1B1IAY1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS04825
gene id: 1236518:AXF22_RS04825
uniprot id: A0A1B1I7P2
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS02180
gene id: 1236518:AXF22_RS02180
uniprot id: A0A1B1I6D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS02895
gene id: 1236518:AXF22_RS02895
uniprot id: A0A1B1I6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1236518:AXF22 RS00735
gene id: 1236518:AXF22_RS00735
uniprot id: A0A1B1I5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS11025
gene id: 1236518:AXF22_RS11025
uniprot id: A0A1B1IAZ5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1236518:AXF22 RS07340
gene id: 1236518:AXF22_RS07340
uniprot id: A0A1B1I8V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1236518:AXF22 RS10895
gene id: 1236518:AXF22_RS10895
uniprot id: A0A1B1ICE9
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS07025
gene id: 1236518:AXF22_RS07025
uniprot id: A0A1B1I8V3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1236518:AXF22 RS01020
gene id: 1236518:AXF22_RS01020
uniprot id: A0A1B1I5S0
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1236518:AXF22 RS05715
gene id: 1236518:AXF22_RS05715
uniprot id: A0A1B1I826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1236518:AXF22 RS02960
gene id: 1236518:AXF22_RS02960
uniprot id: A0A1B1I6R3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1236518:AXF22 RS12450
gene id: 1236518:AXF22_RS12450
uniprot id: A0A1B1IBQ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1236518:AXF22 RS03260
gene id: 1236518:AXF22_RS03260
uniprot id: A0A1B1I6W9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1236518:AXF22 RS06755
gene id: 1236518:AXF22_RS06755
uniprot id: A0A1B1I8Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1236518:AXF22 RS04725
gene id: 1236518:AXF22_RS04725
uniprot id: A0A1B1I7M7
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS05235
gene id: 1236518:AXF22_RS05235
uniprot id: A0A1B1I7V2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS05650
gene id: 1236518:AXF22_RS05650
uniprot id: A0A1B1I874
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1236518:AXF22 RS12630
gene id: 1236518:AXF22_RS12630
uniprot id: A0A1B1IBS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1236518:AXF22 RS08075
gene id: 1236518:AXF22_RS08075
uniprot id: A0A1B1I9L4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1236518:AXF22 RS00025
gene id: 1236518:AXF22_RS00025
uniprot id: A0A1B1I5G8
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

1236518:AXF22 RS11155
gene id: 1236518:AXF22_RS11155
uniprot id: A0A1B1IB35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1236518:AXF22 RS12425
gene id: 1236518:AXF22_RS12425
uniprot id: A0A1B1IBM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1236518:AXF22 RS07570
gene id: 1236518:AXF22_RS07570
uniprot id: A0A1B1I9B4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1236518:AXF22 RS12975
gene id: 1236518:AXF22_RS12975
uniprot id: A0A1B1IBX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1236518:AXF22 RS12805
gene id: 1236518:AXF22_RS12805
uniprot id: A0A1B1IBW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1236518:AXF22 RS00110
gene id: 1236518:AXF22_RS00110
uniprot id: A0A1B1I5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS09425
gene id: 1236518:AXF22_RS09425
uniprot id: A0A1B1IAA7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1236518:AXF22 RS12650
gene id: 1236518:AXF22_RS12650
uniprot id: A0A1B1IBU8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1236518:AXF22 RS05465
gene id: 1236518:AXF22_RS05465
uniprot id: A0A1B1I7Z2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1236518:AXF22 RS00930
gene id: 1236518:AXF22_RS00930
uniprot id: A0A1B1I5T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS09625
gene id: 1236518:AXF22_RS09625
uniprot id: A0A1B1IAE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1236518:AXF22 RS02285
gene id: 1236518:AXF22_RS02285
uniprot id: A0A1B1I6G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1236518:AXF22 RS08880
gene id: 1236518:AXF22_RS08880
uniprot id: A0A1B1I9Z0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1236518:AXF22 RS05690
gene id: 1236518:AXF22_RS05690
uniprot id: A0A1B1I831
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1236518:AXF22 RS08210
gene id: 1236518:AXF22_RS08210
uniprot id: A0A1B1I9V1
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS07175
gene id: 1236518:AXF22_RS07175
uniprot id: A0A1B1I8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS01105
gene id: 1236518:AXF22_RS01105
uniprot id: A0A1B1I5Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1236518:AXF22 RS07330
gene id: 1236518:AXF22_RS07330
uniprot id: A0A1B1I8V9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1236518:AXF22 RS00040
gene id: 1236518:AXF22_RS00040
uniprot id: A0A1B1I5C6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1236518:AXF22 RS03760
gene id: 1236518:AXF22_RS03760
uniprot id: A0A1B1I735
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS06955
gene id: 1236518:AXF22_RS06955
uniprot id: A0A1B1I8U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1236518:AXF22 RS02025
gene id: 1236518:AXF22_RS02025
uniprot id: A0A1B1I689
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1236518:AXF22 RS06315
gene id: 1236518:AXF22_RS06315
uniprot id: A0A1B1I8E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1236518:AXF22 RS03040
gene id: 1236518:AXF22_RS03040
uniprot id: A0A1B1I6X3
names: Similarity
messages: Belongs to the Dps family.

1236518:AXF22 RS04545
gene id: 1236518:AXF22_RS04545
uniprot id: A0A1B1I7I2
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS07390
gene id: 1236518:AXF22_RS07390
uniprot id: A0A1B1I8W0
names: Similarity
messages: Belongs to the MreC family.

1236518:AXF22 RS05195
gene id: 1236518:AXF22_RS05195
uniprot id: A0A1B1I7T6
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS06870
gene id: 1236518:AXF22_RS06870
uniprot id: A0A1B1I8S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1236518:AXF22 RS11735
gene id: 1236518:AXF22_RS11735
uniprot id: A0A1B1IBD4
names: Similarity
messages: Belongs to the CapA family.

1236518:AXF22 RS13045
gene id: 1236518:AXF22_RS13045
uniprot id: A0A1B1ICB8
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1236518:AXF22 RS11055
gene id: 1236518:AXF22_RS11055
uniprot id: A0A1B1IAZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1236518:AXF22 RS11415
gene id: 1236518:AXF22_RS11415
uniprot id: A0A1B1IB92
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS12735
gene id: 1236518:AXF22_RS12735
uniprot id: A0A1B1IBY6
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1236518:AXF22 RS10020
gene id: 1236518:AXF22_RS10020
uniprot id: A0A1B1IAK6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1236518:AXF22 RS06880
gene id: 1236518:AXF22_RS06880
uniprot id: A0A1B1I8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1236518:AXF22 RS04075
gene id: 1236518:AXF22_RS04075
uniprot id: A0A1B1I7E1
names: Similarity
messages: Belongs to the HSP15 family.

1236518:AXF22 RS09475
gene id: 1236518:AXF22_RS09475
uniprot id: A0A1B1IC49
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1236518:AXF22 RS07125
gene id: 1236518:AXF22_RS07125
uniprot id: A0A1B1I8R0
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS01325
gene id: 1236518:AXF22_RS01325
uniprot id: A0A1B1I5Y0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1236518:AXF22 RS01015
gene id: 1236518:AXF22_RS01015
uniprot id: A0A1B1I5S5
names: Similarity
messages: Belongs to the LOG family.

1236518:AXF22 RS05045
gene id: 1236518:AXF22_RS05045
uniprot id: A0A1B1I7W4
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

1236518:AXF22 RS11315
gene id: 1236518:AXF22_RS11315
uniprot id: A0A1B1IB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1236518:AXF22 RS01195
gene id: 1236518:AXF22_RS01195
uniprot id: A0A1B1I5V8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS00525
gene id: 1236518:AXF22_RS00525
uniprot id: A0A1B1I5I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1236518:AXF22 RS12140
gene id: 1236518:AXF22_RS12140
uniprot id: A0A1B1IBI6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1236518:AXF22 RS04665
gene id: 1236518:AXF22_RS04665
uniprot id: A0A1B1I7K8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1236518:AXF22 RS10910
gene id: 1236518:AXF22_RS10910
uniprot id: A0A1B1IAZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS04465
gene id: 1236518:AXF22_RS04465
uniprot id: A0A1B1I7L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1236518:AXF22 RS08050
gene id: 1236518:AXF22_RS08050
uniprot id: A0A1B1IBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS07440
gene id: 1236518:AXF22_RS07440
uniprot id: A0A1B1I8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1236518:AXF22 RS04790
gene id: 1236518:AXF22_RS04790
uniprot id: A0A1B1I7S6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1236518:AXF22 RS00530
gene id: 1236518:AXF22_RS00530
uniprot id: A0A1B1I5I2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1236518:AXF22 RS07365
gene id: 1236518:AXF22_RS07365
uniprot id: A0A1B1I8U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

1236518:AXF22 RS05300
gene id: 1236518:AXF22_RS05300
uniprot id: A0A1B1I9C5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1236518:AXF22 RS02790
gene id: 1236518:AXF22_RS02790
uniprot id: A0A1B1I6S6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1236518:AXF22 RS05420
gene id: 1236518:AXF22_RS05420
uniprot id: A0A1B1I800
names: Similarity
messages: Belongs to the XseB family.

1236518:AXF22 RS00870
gene id: 1236518:AXF22_RS00870
uniprot id: A0A1B1I5Q1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1236518:AXF22 RS12355
gene id: 1236518:AXF22_RS12355
uniprot id: A0A1B1IBN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1236518:AXF22 RS07350
gene id: 1236518:AXF22_RS07350
uniprot id: A0A1B1I910
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1236518:AXF22 RS08625
gene id: 1236518:AXF22_RS08625
uniprot id: A0A1B1I9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1236518:AXF22 RS03735
gene id: 1236518:AXF22_RS03735
uniprot id: A0A1B1I780
names: Similarity
messages: Belongs to the peptidase M16 family.

1236518:AXF22 RS04585
gene id: 1236518:AXF22_RS04585
uniprot id: A0A1B1I7J5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1236518:AXF22 RS12145
gene id: 1236518:AXF22_RS12145
uniprot id: A0A1B1IBK1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1236518:AXF22 RS02460
gene id: 1236518:AXF22_RS02460
uniprot id: A0A1B1I6K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS00625
gene id: 1236518:AXF22_RS00625
uniprot id: A0A1B1I5K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1236518:AXF22 RS01475
gene id: 1236518:AXF22_RS01475
uniprot id: A0A1B1I621
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1236518:AXF22 RS11590
gene id: 1236518:AXF22_RS11590
uniprot id: A0A1B1IB91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1236518:AXF22 RS12415
gene id: 1236518:AXF22_RS12415
uniprot id: A0A1B1IBN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS06635
gene id: 1236518:AXF22_RS06635
uniprot id: A0A1B1I8H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1236518:AXF22 RS08195
gene id: 1236518:AXF22_RS08195
uniprot id: A0A1B1I9L9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1236518:AXF22 RS05135
gene id: 1236518:AXF22_RS05135
uniprot id: A0A1B1I7X4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1236518:AXF22 RS09190
gene id: 1236518:AXF22_RS09190
uniprot id: A0A1B1IA36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS00390
gene id: 1236518:AXF22_RS00390
uniprot id: A0A1B1I5H4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS07320
gene id: 1236518:AXF22_RS07320
uniprot id: A0A1B1I903
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS08785
gene id: 1236518:AXF22_RS08785
uniprot id: A0A1B1IA34
names: Similarity
messages: Belongs to the aldose epimerase family.

1236518:AXF22 RS12420
gene id: 1236518:AXF22_RS12420
uniprot id: A0A1B1IBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1236518:AXF22 RS04080
gene id: 1236518:AXF22_RS04080
uniprot id: A0A1B1I7A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1236518:AXF22 RS00640
gene id: 1236518:AXF22_RS00640
uniprot id: A0A1B1I5K5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1236518:AXF22 RS02175
gene id: 1236518:AXF22_RS02175
uniprot id: A0A1B1I6D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1236518:AXF22 RS09655
gene id: 1236518:AXF22_RS09655
uniprot id: A0A1B1IAE5
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS00090
gene id: 1236518:AXF22_RS00090
uniprot id: A0A1B1I5C5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1236518:AXF22 RS11345
gene id: 1236518:AXF22_RS11345
uniprot id: A0A1B1IBB2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1236518:AXF22 RS06430
gene id: 1236518:AXF22_RS06430
uniprot id: A0A1B1I8E3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1236518:AXF22 RS00540
gene id: 1236518:AXF22_RS00540
uniprot id: A0A1B1I5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS02200
gene id: 1236518:AXF22_RS02200
uniprot id: A0A1B1I6E0
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1236518:AXF22 RS02660
gene id: 1236518:AXF22_RS02660
uniprot id: A0A1B1I6K6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1236518:AXF22 RS12495
gene id: 1236518:AXF22_RS12495
uniprot id: A0A1B1IBS6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1236518:AXF22 RS09955
gene id: 1236518:AXF22_RS09955
uniprot id: A0A1B1IBJ5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1236518:AXF22 RS02115
gene id: 1236518:AXF22_RS02115
uniprot id: A0A1B1I6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1236518:AXF22 RS02615
gene id: 1236518:AXF22_RS02615
uniprot id: A0A1B1I6M8
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS12225
gene id: 1236518:AXF22_RS12225
uniprot id: A0A1B1IBK2
names: Similarity
messages: Belongs to the UPF0246 family.

1236518:AXF22 RS00950
gene id: 1236518:AXF22_RS00950
uniprot id: A0A1B1I5X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1236518:AXF22 RS09885
gene id: 1236518:AXF22_RS09885
uniprot id: A0A1B1IAI5
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS08645
gene id: 1236518:AXF22_RS08645
uniprot id: A0A1B1I9U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1236518:AXF22 RS07745
gene id: 1236518:AXF22_RS07745
uniprot id: A0A1B1I9J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1236518:AXF22 RS06360
gene id: 1236518:AXF22_RS06360
uniprot id: A0A1B1I8D3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS06085
gene id: 1236518:AXF22_RS06085
uniprot id: A0A1B1I896
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS02015
gene id: 1236518:AXF22_RS02015
uniprot id: A0A1B1I692
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1236518:AXF22 RS12660
gene id: 1236518:AXF22_RS12660
uniprot id: A0A1B1ICB6
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS07475
gene id: 1236518:AXF22_RS07475
uniprot id: A0A1B1I8W9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1236518:AXF22 RS09845
gene id: 1236518:AXF22_RS09845
uniprot id: A0A1B1IAG3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS02375
gene id: 1236518:AXF22_RS02375
uniprot id: A0A1B1I6G3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS04970
gene id: 1236518:AXF22_RS04970
uniprot id: A0A1B1I7R0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1236518:AXF22 RS12615
gene id: 1236518:AXF22_RS12615
uniprot id: A0A1B1IBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1236518:AXF22 RS03510
gene id: 1236518:AXF22_RS03510
uniprot id: A0A1B1I710
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS09570
gene id: 1236518:AXF22_RS09570
uniprot id: A0A1B1IAB1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1236518:AXF22 RS02605
gene id: 1236518:AXF22_RS02605
uniprot id: A0A1B1I6K2
names: Similarity
messages: Belongs to the SusD family.

1236518:AXF22 RS08635
gene id: 1236518:AXF22_RS08635
uniprot id: A0A1B1I9W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1236518:AXF22 RS06815
gene id: 1236518:AXF22_RS06815
uniprot id: A0A1B1I8R3
names: Subcellular Location Annotation
messages: Cytoplasm

1236518:AXF22 RS11175
gene id: 1236518:AXF22_RS11175
uniprot id: A0A1B1IB71
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS02150
gene id: 1236518:AXF22_RS02150
uniprot id: A0A1B1I6D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1236518:AXF22 RS07990
gene id: 1236518:AXF22_RS07990
uniprot id: A0A1B1I9Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1236518:AXF22 RS03545
gene id: 1236518:AXF22_RS03545
uniprot id: A0A1B1I713
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS10115
gene id: 1236518:AXF22_RS10115
uniprot id: A0A1B1IAT5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1236518:AXF22 RS06965
gene id: 1236518:AXF22_RS06965
uniprot id: A0A1B1I8R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1236518:AXF22 RS04040
gene id: 1236518:AXF22_RS04040
uniprot id: A0A1B1I796
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1236518:AXF22 RS01725
gene id: 1236518:AXF22_RS01725
uniprot id: A0A1B1I663
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1236518:AXF22 RS06885
gene id: 1236518:AXF22_RS06885
uniprot id: A0A1B1I8M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1236518:AXF22 RS02875
gene id: 1236518:AXF22_RS02875
uniprot id: A0A1B1I6Q8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1236518:AXF22 RS08805
gene id: 1236518:AXF22_RS08805
uniprot id: A0A1B1I9X3
names: Similarity
messages: Belongs to the transketolase family.

1236518:AXF22 RS06010
gene id: 1236518:AXF22_RS06010
uniprot id: A0A1B1I880
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1236518:AXF22 RS01010
gene id: 1236518:AXF22_RS01010
uniprot id: A0A1B1I5Y6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1236518:AXF22 RS05705
gene id: 1236518:AXF22_RS05705
uniprot id: A0A1B1I825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1236518:AXF22 RS12890
gene id: 1236518:AXF22_RS12890
uniprot id: A0A1B1IBW8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1236518:AXF22 RS00660
gene id: 1236518:AXF22_RS00660
uniprot id: A0A1B1I5M4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1236518:AXF22 RS06760
gene id: 1236518:AXF22_RS06760
uniprot id: A0A1B1I8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS06320
gene id: 1236518:AXF22_RS06320
uniprot id: A0A1B1I8C8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1236518:AXF22 RS12530
gene id: 1236518:AXF22_RS12530
uniprot id: A0A1B1IBP4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1236518:AXF22 RS11575
gene id: 1236518:AXF22_RS11575
uniprot id: A0A1B1IC82
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS05410
gene id: 1236518:AXF22_RS05410
uniprot id: A0A1B1I7Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1236518:AXF22 RS12935
gene id: 1236518:AXF22_RS12935
uniprot id: A0A1B1IC00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1236518:AXF22 RS02925
gene id: 1236518:AXF22_RS02925
uniprot id: A0A1B1I6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1236518:AXF22 RS07435
gene id: 1236518:AXF22_RS07435
uniprot id: A0A1B1I8X4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1236518:AXF22 RS02740
gene id: 1236518:AXF22_RS02740
uniprot id: A0A1B1I6N7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1236518:AXF22 RS08045
gene id: 1236518:AXF22_RS08045
uniprot id: A0A1B1I9Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1236518:AXF22 RS11235
gene id: 1236518:AXF22_RS11235
uniprot id: A0A1B1IB27
names: Similarity
messages: Belongs to the peptidase S8 family.

1236518:AXF22 RS00520
gene id: 1236518:AXF22_RS00520
uniprot id: A0A1B1I5L1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1236518:AXF22 RS07850
gene id: 1236518:AXF22_RS07850
uniprot id: A0A1B1I9N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1236518:AXF22 RS02525
gene id: 1236518:AXF22_RS02525
uniprot id: A0A1B1I6N8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1236518:AXF22 RS00470
gene id: 1236518:AXF22_RS00470
uniprot id: A0A1B1I5J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1236518:AXF22 RS03235
gene id: 1236518:AXF22_RS03235
uniprot id: A0A1B1I6X1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1236518:AXF22 RS00495
gene id: 1236518:AXF22_RS00495
uniprot id: A0A1B1I5J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1236518:AXF22 RS09970
gene id: 1236518:AXF22_RS09970
uniprot id: A0A1B1IAJ6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1236518:AXF22 RS00100
gene id: 1236518:AXF22_RS00100
uniprot id: A0A1B1I5H9
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

1236518:AXF22 RS11995
gene id: 1236518:AXF22_RS11995
uniprot id: A0A1B1IBM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1236518:AXF22 RS11550
gene id: 1236518:AXF22_RS11550
uniprot id: A0A1B1IB88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1236518:AXF22 RS08720
gene id: 1236518:AXF22_RS08720
uniprot id: A0A1B1I9Y7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1236518:AXF22 RS01880
gene id: 1236518:AXF22_RS01880
uniprot id: A0A1B1I696
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1236518:AXF22 RS04815
gene id: 1236518:AXF22_RS04815
uniprot id: A0A1B1I7M8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1236518:AXF22 RS11380
gene id: 1236518:AXF22_RS11380
uniprot id: A0A1B1IB95
names: Subcellular Location Annotation
messages: Membrane

1236518:AXF22 RS06920
gene id: 1236518:AXF22_RS06920
uniprot id: A0A1B1I8T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1236518:AXF22 RS07040
gene id: 1236518:AXF22_RS07040
uniprot id: A0A1B1I8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS02450
gene id: 1236518:AXF22_RS02450
uniprot id: A0A1B1I6J2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1236518:AXF22 RS01640
gene id: 1236518:AXF22_RS01640
uniprot id: A0A1B1I649
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1236518:AXF22 RS01280
gene id: 1236518:AXF22_RS01280
uniprot id: A0A1B1I632
names: Similarity
messages: Belongs to the DprA/Smf family.