1235441:CDO52 RS08780
gene id: 1235441:CDO52_RS08780
uniprot id: A0A223S405
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1235441:CDO52 RS09775
gene id: 1235441:CDO52_RS09775
uniprot id: A0A223SD98
names: Similarity
messages: Belongs to the peptidase S45 family.

1235441:CDO52 RS25090
gene id: 1235441:CDO52_RS25090
uniprot id: A0A223SC23
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1235441:CDO52 RS23800
gene id: 1235441:CDO52_RS23800
uniprot id: A0A223SBF5
names: Subcellular Location Annotation
messages: Cytoplasm

1235441:CDO52 RS01095
gene id: 1235441:CDO52_RS01095
uniprot id: A0A223S0D9
names: Similarity
messages: Belongs to the GARS family.

1235441:CDO52 RS12000
gene id: 1235441:CDO52_RS12000
uniprot id: A0A223S5K7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1235441:CDO52 RS02310
gene id: 1235441:CDO52_RS02310
uniprot id: A0A223S0W4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1235441:CDO52 RS00385
gene id: 1235441:CDO52_RS00385
uniprot id: A0A223S012
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS20910
gene id: 1235441:CDO52_RS20910
uniprot id: A0A223S9Z3
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

1235441:CDO52 RS11870
gene id: 1235441:CDO52_RS11870
uniprot id: A0A223S5I7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS12145
gene id: 1235441:CDO52_RS12145
uniprot id: A0A223S5L8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1235441:CDO52 RS19645
gene id: 1235441:CDO52_RS19645
uniprot id: A0A223S9C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1235441:CDO52 RS11850
gene id: 1235441:CDO52_RS11850
uniprot id: A0A223S5S8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1235441:CDO52 RS24995
gene id: 1235441:CDO52_RS24995
uniprot id: A0A223SC00
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1235441:CDO52 RS25195
gene id: 1235441:CDO52_RS25195
uniprot id: A0A223SC48
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1235441:CDO52 RS22665
gene id: 1235441:CDO52_RS22665
uniprot id: A0A223SAQ1
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS10205
gene id: 1235441:CDO52_RS10205
uniprot id: A0A223S4S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1235441:CDO52 RS08550
gene id: 1235441:CDO52_RS08550
uniprot id: A0A223S3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1235441:CDO52 RS03870
gene id: 1235441:CDO52_RS03870
uniprot id: A0A223S1L9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1235441:CDO52 RS17920
gene id: 1235441:CDO52_RS17920
uniprot id: A0A223S8H6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1235441:CDO52 RS16840
gene id: 1235441:CDO52_RS16840
uniprot id: A0A223S807
names: Similarity
messages: Belongs to the CdaR family.

1235441:CDO52 RS08555
gene id: 1235441:CDO52_RS08555
uniprot id: A0A223S3W8
names: Similarity
messages: Belongs to the AHA1 family.

1235441:CDO52 RS02680
gene id: 1235441:CDO52_RS02680
uniprot id: A0A223S146
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1235441:CDO52 RS23140
gene id: 1235441:CDO52_RS23140
uniprot id: A0A223SAW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1235441:CDO52 RS14850
gene id: 1235441:CDO52_RS14850
uniprot id: A0A223S6Y8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS19855
gene id: 1235441:CDO52_RS19855
uniprot id: A0A223SE91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS05265
gene id: 1235441:CDO52_RS05265
uniprot id: A0A223S2C3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS25060
gene id: 1235441:CDO52_RS25060
uniprot id: A0A223SBS9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1235441:CDO52 RS18845
gene id: 1235441:CDO52_RS18845
uniprot id: A0A223S927
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1235441:CDO52 RS16140
gene id: 1235441:CDO52_RS16140
uniprot id: A0A223S7L0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1235441:CDO52 RS24565
gene id: 1235441:CDO52_RS24565
uniprot id: A0A223SBK8
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS14295
gene id: 1235441:CDO52_RS14295
uniprot id: A0A223S6P4
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1235441:CDO52 RS05225
gene id: 1235441:CDO52_RS05225
uniprot id: A0A223S2B2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1235441:CDO52 RS20360
gene id: 1235441:CDO52_RS20360
uniprot id: A0A223S9M2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1235441:CDO52 RS08925
gene id: 1235441:CDO52_RS08925
uniprot id: A0A223SDH0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1235441:CDO52 RS03385
gene id: 1235441:CDO52_RS03385
uniprot id: A0A223S1H9
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25640
gene id: 1235441:CDO52_RS25640
uniprot id: A0A223SCB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1235441:CDO52 RS11455
gene id: 1235441:CDO52_RS11455
uniprot id: A0A223S5F4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1235441:CDO52 RS20150
gene id: 1235441:CDO52_RS20150
uniprot id: A0A223S9L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1235441:CDO52 RS14710
gene id: 1235441:CDO52_RS14710
uniprot id: A0A223S6W2
names: Similarity
messages: Belongs to the peptidase M24B family.

1235441:CDO52 RS26210
gene id: 1235441:CDO52_RS26210
uniprot id: A0A223SCL6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1235441:CDO52 RS10395
gene id: 1235441:CDO52_RS10395
uniprot id: A0A223S4S7
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS22630
gene id: 1235441:CDO52_RS22630
uniprot id: A0A223SAP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1235441:CDO52 RS23020
gene id: 1235441:CDO52_RS23020
uniprot id: A0A223SB09
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1235441:CDO52 RS18820
gene id: 1235441:CDO52_RS18820
uniprot id: A0A223S904
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS02065
gene id: 1235441:CDO52_RS02065
uniprot id: A0A223S0X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1235441:CDO52 RS15340
gene id: 1235441:CDO52_RS15340
uniprot id: A0A223S7C6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1235441:CDO52 RS01400
gene id: 1235441:CDO52_RS01400
uniprot id: A0A223S0T3
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS02245
gene id: 1235441:CDO52_RS02245
uniprot id: A0A223S0X5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1235441:CDO52 RS18070
gene id: 1235441:CDO52_RS18070
uniprot id: A0A223S8K7
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS18585
gene id: 1235441:CDO52_RS18585
uniprot id: A0A223S8W7
names: Similarity
messages: Belongs to the oxoprolinase family.

1235441:CDO52 RS08870
gene id: 1235441:CDO52_RS08870
uniprot id: A0A223S422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS16960
gene id: 1235441:CDO52_RS16960
uniprot id: A0A223S822
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1235441:CDO52 RS09135
gene id: 1235441:CDO52_RS09135
uniprot id: A0A223S4H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1235441:CDO52 RS03625
gene id: 1235441:CDO52_RS03625
uniprot id: A0A223S1I6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1235441:CDO52 RS26315
gene id: 1235441:CDO52_RS26315
uniprot id: A0A223SCN1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1235441:CDO52 RS13745
gene id: 1235441:CDO52_RS13745
uniprot id: A0A223S6F3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1235441:CDO52 RS18715
gene id: 1235441:CDO52_RS18715
uniprot id: A0A223S8X1
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS01945
gene id: 1235441:CDO52_RS01945
uniprot id: A0A223S0S3
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1235441:CDO52 RS18225
gene id: 1235441:CDO52_RS18225
uniprot id: A0A223S8Q0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1235441:CDO52 RS11160
gene id: 1235441:CDO52_RS11160
uniprot id: A0A223S541
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1235441:CDO52 RS18705
gene id: 1235441:CDO52_RS18705
uniprot id: A0A223S8W4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS12455
gene id: 1235441:CDO52_RS12455
uniprot id: A0A223S5U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1235441:CDO52 RS07450
gene id: 1235441:CDO52_RS07450
uniprot id: A0A223SD49
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1235441:CDO52 RS01100
gene id: 1235441:CDO52_RS01100
uniprot id: A0A223S0B9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1235441:CDO52 RS25550
gene id: 1235441:CDO52_RS25550
uniprot id: A0A223SCG7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1235441:CDO52 RS22270
gene id: 1235441:CDO52_RS22270
uniprot id: A0A223SAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS06280
gene id: 1235441:CDO52_RS06280
uniprot id: A0A223S2T6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1235441:CDO52 RS24470
gene id: 1235441:CDO52_RS24470
uniprot id: A0A223SBQ6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1235441:CDO52 RS13875
gene id: 1235441:CDO52_RS13875
uniprot id: A0A223S6I6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS20390
gene id: 1235441:CDO52_RS20390
uniprot id: A0A223S9Q0
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25350
gene id: 1235441:CDO52_RS25350
uniprot id: A0A223SC63
names: Similarity
messages: Belongs to the UPF0336 family.

1235441:CDO52 RS08905
gene id: 1235441:CDO52_RS08905
uniprot id: A0A223S485
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1235441:CDO52 RS03885
gene id: 1235441:CDO52_RS03885
uniprot id: A0A223S1Q7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1235441:CDO52 RS18890
gene id: 1235441:CDO52_RS18890
uniprot id: A0A223SDT6
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1235441:CDO52 RS07750
gene id: 1235441:CDO52_RS07750
uniprot id: A0A223SD73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1235441:CDO52 RS25150
gene id: 1235441:CDO52_RS25150
uniprot id: A0A223SBW3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1235441:CDO52 RS21035
gene id: 1235441:CDO52_RS21035
uniprot id: A0A223S9X3
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

1235441:CDO52 RS23995
gene id: 1235441:CDO52_RS23995
uniprot id: A0A223SBH3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1235441:CDO52 RS12375
gene id: 1235441:CDO52_RS12375
uniprot id: A0A223S5S4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS10060
gene id: 1235441:CDO52_RS10060
uniprot id: A0A223SDR5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1235441:CDO52 RS04495
gene id: 1235441:CDO52_RS04495
uniprot id: A0A223S1Y2
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS03480
gene id: 1235441:CDO52_RS03480
uniprot id: A0A223S1I4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1235441:CDO52 RS16365
gene id: 1235441:CDO52_RS16365
uniprot id: A0A223S7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS13835
gene id: 1235441:CDO52_RS13835
uniprot id: A0A223S6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS16275
gene id: 1235441:CDO52_RS16275
uniprot id: A0A223S7Q7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1235441:CDO52 RS23990
gene id: 1235441:CDO52_RS23990
uniprot id: A0A223SBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1235441:CDO52 RS05250
gene id: 1235441:CDO52_RS05250
uniprot id: A0A223S2A5
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25260
gene id: 1235441:CDO52_RS25260
uniprot id: A0A223SCC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1235441:CDO52 RS14450
gene id: 1235441:CDO52_RS14450
uniprot id: A0A223S6T0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1235441:CDO52 RS15165
gene id: 1235441:CDO52_RS15165
uniprot id: A0A223S776
names: Similarity
messages: Belongs to the peptidase S8 family.

1235441:CDO52 RS26685
gene id: 1235441:CDO52_RS26685
uniprot id: A0A223SCU4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25565
gene id: 1235441:CDO52_RS25565
uniprot id: A0A223SC92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1235441:CDO52 RS18650
gene id: 1235441:CDO52_RS18650
uniprot id: A0A223S8V1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1235441:CDO52 RS25280
gene id: 1235441:CDO52_RS25280
uniprot id: A0A223SC81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1235441:CDO52 RS02835
gene id: 1235441:CDO52_RS02835
uniprot id: A0A223S151
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1235441:CDO52 RS23455
gene id: 1235441:CDO52_RS23455
uniprot id: A0A223SB96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1235441:CDO52 RS04740
gene id: 1235441:CDO52_RS04740
uniprot id: A0A223S232
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1235441:CDO52 RS21300
gene id: 1235441:CDO52_RS21300
uniprot id: A0A223SA87
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS24915
gene id: 1235441:CDO52_RS24915
uniprot id: A0A223SBZ6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1235441:CDO52 RS24695
gene id: 1235441:CDO52_RS24695
uniprot id: A0A223SBL9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1235441:CDO52 RS12620
gene id: 1235441:CDO52_RS12620
uniprot id: A0A223S5W1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1235441:CDO52 RS18665
gene id: 1235441:CDO52_RS18665
uniprot id: A0A223S8W8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1235441:CDO52 RS19125
gene id: 1235441:CDO52_RS19125
uniprot id: A0A223S926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1235441:CDO52 RS22885
gene id: 1235441:CDO52_RS22885
uniprot id: A0A223SAR2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1235441:CDO52 RS03305
gene id: 1235441:CDO52_RS03305
uniprot id: A0A223S1C6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS16010
gene id: 1235441:CDO52_RS16010
uniprot id: A0A223S7M8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1235441:CDO52 RS20470
gene id: 1235441:CDO52_RS20470
uniprot id: A0A223S9T2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1235441:CDO52 RS12015
gene id: 1235441:CDO52_RS12015
uniprot id: A0A223S5M6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1235441:CDO52 RS03755
gene id: 1235441:CDO52_RS03755
uniprot id: A0A223S1K3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS10535
gene id: 1235441:CDO52_RS10535
uniprot id: A0A223S4S8
names: Similarity
messages: Belongs to the UPF0098 family.

1235441:CDO52 RS25520
gene id: 1235441:CDO52_RS25520
uniprot id: A0A223SCB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1235441:CDO52 RS24860
gene id: 1235441:CDO52_RS24860
uniprot id: A0A223SBY3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1235441:CDO52 RS11400
gene id: 1235441:CDO52_RS11400
uniprot id: A0A223S5E5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1235441:CDO52 RS18805
gene id: 1235441:CDO52_RS18805
uniprot id: A0A223S8X7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1235441:CDO52 RS06495
gene id: 1235441:CDO52_RS06495
uniprot id: A0A223S2W7
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS02395
gene id: 1235441:CDO52_RS02395
uniprot id: A0A223S189
names: Similarity
messages: Belongs to the NodU/CmcH family.

1235441:CDO52 RS05535
gene id: 1235441:CDO52_RS05535
uniprot id: A0A223S2M3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS14745
gene id: 1235441:CDO52_RS14745
uniprot id: A0A223S6X3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS23520
gene id: 1235441:CDO52_RS23520
uniprot id: A0A223SB37
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1235441:CDO52 RS06225
gene id: 1235441:CDO52_RS06225
uniprot id: A0A223S2S6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS02370
gene id: 1235441:CDO52_RS02370
uniprot id: A0A223S116
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1235441:CDO52 RS25335
gene id: 1235441:CDO52_RS25335
uniprot id: A0A223SC55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1235441:CDO52 RS24760
gene id: 1235441:CDO52_RS24760
uniprot id: A0A223SBN0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS05685
gene id: 1235441:CDO52_RS05685
uniprot id: A0A223S2J0
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1235441:CDO52 RS24715
gene id: 1235441:CDO52_RS24715
uniprot id: A0A223SBN4
names: Subcellular Location Annotation
messages: Cytoplasm

1235441:CDO52 RS23125
gene id: 1235441:CDO52_RS23125
uniprot id: A0A223SAV4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1235441:CDO52 RS19305
gene id: 1235441:CDO52_RS19305
uniprot id: A0A223S960
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1235441:CDO52 RS13880
gene id: 1235441:CDO52_RS13880
uniprot id: A0A223S6H6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1235441:CDO52 RS02910
gene id: 1235441:CDO52_RS02910
uniprot id: A0A223S169
names: Similarity
messages: Belongs to the thioesterase family.

1235441:CDO52 RS01645
gene id: 1235441:CDO52_RS01645
uniprot id: A0A223S0L7
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1235441:CDO52 RS20605
gene id: 1235441:CDO52_RS20605
uniprot id: A0A223S9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS11715
gene id: 1235441:CDO52_RS11715
uniprot id: A0A223S5F5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1235441:CDO52 RS26730
gene id: 1235441:CDO52_RS26730
uniprot id: A0A223SCM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS10265
gene id: 1235441:CDO52_RS10265
uniprot id: A0A223S4Q6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS09685
gene id: 1235441:CDO52_RS09685
uniprot id: A0A223S4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1235441:CDO52 RS15415
gene id: 1235441:CDO52_RS15415
uniprot id: A0A223S791
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS14780
gene id: 1235441:CDO52_RS14780
uniprot id: A0A223S6X7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS09250
gene id: 1235441:CDO52_RS09250
uniprot id: A0A223S486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

1235441:CDO52 RS26190
gene id: 1235441:CDO52_RS26190
uniprot id: A0A223SCL7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS14880
gene id: 1235441:CDO52_RS14880
uniprot id: A0A223S738
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1235441:CDO52 RS10675
gene id: 1235441:CDO52_RS10675
uniprot id: A0A223S591
names: Similarity
messages: Belongs to the GcvT family.

1235441:CDO52 RS26035
gene id: 1235441:CDO52_RS26035
uniprot id: A0A223SCI6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS04020
gene id: 1235441:CDO52_RS04020
uniprot id: A0A223S1Q9
names: Similarity
messages: Belongs to the AHA1 family.

1235441:CDO52 RS09320
gene id: 1235441:CDO52_RS09320
uniprot id: A0A223S4D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1235441:CDO52 RS02075
gene id: 1235441:CDO52_RS02075
uniprot id: A0A223S0U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1235441:CDO52 RS01145
gene id: 1235441:CDO52_RS01145
uniprot id: A0A223S0C7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1235441:CDO52 RS18545
gene id: 1235441:CDO52_RS18545
uniprot id: A0A223S8T0
names: Similarity
messages: Belongs to the UPF0047 family.

1235441:CDO52 RS19000
gene id: 1235441:CDO52_RS19000
uniprot id: A0A223S932
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1235441:CDO52 RS09330
gene id: 1235441:CDO52_RS09330
uniprot id: A0A223S4B3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1235441:CDO52 RS01630
gene id: 1235441:CDO52_RS01630
uniprot id: A0A223S0X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1235441:CDO52 RS21295
gene id: 1235441:CDO52_RS21295
uniprot id: A0A223SA42
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS02090
gene id: 1235441:CDO52_RS02090
uniprot id: A0A223S0V0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1235441:CDO52 RS21045
gene id: 1235441:CDO52_RS21045
uniprot id: A0A223SA18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

1235441:CDO52 RS06330
gene id: 1235441:CDO52_RS06330
uniprot id: A0A223S2V2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1235441:CDO52 RS09295
gene id: 1235441:CDO52_RS09295
uniprot id: A0A223S4J9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS05540
gene id: 1235441:CDO52_RS05540
uniprot id: A0A223S2H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1235441:CDO52 RS25725
gene id: 1235441:CDO52_RS25725
uniprot id: A0A223SCK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1235441:CDO52 RS17960
gene id: 1235441:CDO52_RS17960
uniprot id: A0A223S8L3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1235441:CDO52 RS03735
gene id: 1235441:CDO52_RS03735
uniprot id: A0A223S1L4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS26055
gene id: 1235441:CDO52_RS26055
uniprot id: A0A223SCH1
names: Similarity
messages: Belongs to the asparaginase 1 family.

1235441:CDO52 RS25805
gene id: 1235441:CDO52_RS25805
uniprot id: A0A223SCD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1235441:CDO52 RS22925
gene id: 1235441:CDO52_RS22925
uniprot id: A0A223SAS5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1235441:CDO52 RS23805
gene id: 1235441:CDO52_RS23805
uniprot id: A0A223SB91
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS06105
gene id: 1235441:CDO52_RS06105
uniprot id: A0A223S319
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS01460
gene id: 1235441:CDO52_RS01460
uniprot id: A0A223SCY0
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS00520
gene id: 1235441:CDO52_RS00520
uniprot id: A0A223S003
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS04090
gene id: 1235441:CDO52_RS04090
uniprot id: A0A223S1W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1235441:CDO52 RS04075
gene id: 1235441:CDO52_RS04075
uniprot id: A0A223S1R8
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1235441:CDO52 RS04680
gene id: 1235441:CDO52_RS04680
uniprot id: A0A223S202
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS09280
gene id: 1235441:CDO52_RS09280
uniprot id: A0A223S493
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS25570
gene id: 1235441:CDO52_RS25570
uniprot id: A0A223SCC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1235441:CDO52 RS09050
gene id: 1235441:CDO52_RS09050
uniprot id: A0A223S456
names: Similarity
messages: Belongs to the FPG family.

1235441:CDO52 RS22600
gene id: 1235441:CDO52_RS22600
uniprot id: A0A223SAP5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1235441:CDO52 RS13390
gene id: 1235441:CDO52_RS13390
uniprot id: A0A223SDN5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1235441:CDO52 RS12115
gene id: 1235441:CDO52_RS12115
uniprot id: A0A223S5N1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1235441:CDO52 RS09715
gene id: 1235441:CDO52_RS09715
uniprot id: A0A223S4H0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1235441:CDO52 RS24635
gene id: 1235441:CDO52_RS24635
uniprot id: A0A223SBK9
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS12575
gene id: 1235441:CDO52_RS12575
uniprot id: A0A223S5W7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1235441:CDO52 RS23545
gene id: 1235441:CDO52_RS23545
uniprot id: A0A223SB84
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1235441:CDO52 RS19170
gene id: 1235441:CDO52_RS19170
uniprot id: A0A223S937
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1235441:CDO52 RS08050
gene id: 1235441:CDO52_RS08050
uniprot id: A0A223S3Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1235441:CDO52 RS15325
gene id: 1235441:CDO52_RS15325
uniprot id: A0A223S768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1235441:CDO52 RS26895
gene id: 1235441:CDO52_RS26895
uniprot id: A0A223SCX2
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS22065
gene id: 1235441:CDO52_RS22065
uniprot id: A0A223SAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS25740
gene id: 1235441:CDO52_RS25740
uniprot id: A0A223SC60
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1235441:CDO52 RS18495
gene id: 1235441:CDO52_RS18495
uniprot id: A0A223S8T6
names: Similarity
messages: Belongs to the hyi family.

1235441:CDO52 RS03060
gene id: 1235441:CDO52_RS03060
uniprot id: A0A223S196
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1235441:CDO52 RS11935
gene id: 1235441:CDO52_RS11935
uniprot id: A0A223S5J3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1235441:CDO52 RS08920
gene id: 1235441:CDO52_RS08920
uniprot id: A0A223S443
names: Similarity
messages: Belongs to the UPF0102 family.

1235441:CDO52 RS22815
gene id: 1235441:CDO52_RS22815
uniprot id: A0A223SB00
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1235441:CDO52 RS08270
gene id: 1235441:CDO52_RS08270
uniprot id: A0A223S3R0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1235441:CDO52 RS04805
gene id: 1235441:CDO52_RS04805
uniprot id: A0A223S244
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1235441:CDO52 RS04900
gene id: 1235441:CDO52_RS04900
uniprot id: A0A223S2G5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1235441:CDO52 RS00490
gene id: 1235441:CDO52_RS00490
uniprot id: A0A223S007
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS14915
gene id: 1235441:CDO52_RS14915
uniprot id: A0A223S750
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS24560
gene id: 1235441:CDO52_RS24560
uniprot id: A0A223SBM0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1235441:CDO52 RS18020
gene id: 1235441:CDO52_RS18020
uniprot id: A0A223S8J8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1235441:CDO52 RS24720
gene id: 1235441:CDO52_RS24720
uniprot id: A0A223SBV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1235441:CDO52 RS22945
gene id: 1235441:CDO52_RS22945
uniprot id: A0A223SAY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1235441:CDO52 RS07170
gene id: 1235441:CDO52_RS07170
uniprot id: A0A223S382
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1235441:CDO52 RS17995
gene id: 1235441:CDO52_RS17995
uniprot id: A0A223S8J3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1235441:CDO52 RS20315
gene id: 1235441:CDO52_RS20315
uniprot id: A0A223S9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1235441:CDO52 RS07920
gene id: 1235441:CDO52_RS07920
uniprot id: A0A223S3M0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1235441:CDO52 RS18100
gene id: 1235441:CDO52_RS18100
uniprot id: A0A223S8L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS01410
gene id: 1235441:CDO52_RS01410
uniprot id: A0A223S0H6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS12635
gene id: 1235441:CDO52_RS12635
uniprot id: A0A223S5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1235441:CDO52 RS08820
gene id: 1235441:CDO52_RS08820
uniprot id: A0A223S418
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1235441:CDO52 RS17015
gene id: 1235441:CDO52_RS17015
uniprot id: A0A223S832
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS20595
gene id: 1235441:CDO52_RS20595
uniprot id: A0A223S9V8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1235441:CDO52 RS12075
gene id: 1235441:CDO52_RS12075
uniprot id: A0A223S5N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1235441:CDO52 RS15610
gene id: 1235441:CDO52_RS15610
uniprot id: A0A223S7D4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1235441:CDO52 RS13495
gene id: 1235441:CDO52_RS13495
uniprot id: A0A223S6E1
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1235441:CDO52 RS06515
gene id: 1235441:CDO52_RS06515
uniprot id: A0A223S2Y4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS14170
gene id: 1235441:CDO52_RS14170
uniprot id: A0A223S6P9
names: Similarity
messages: Belongs to the isochorismate synthase family.

1235441:CDO52 RS13425
gene id: 1235441:CDO52_RS13425
uniprot id: A0A223S6A6
names: Similarity
messages: Belongs to the peptidase U62 family.

1235441:CDO52 RS00245
gene id: 1235441:CDO52_RS00245
uniprot id: A0A223RZZ6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1235441:CDO52 RS21480
gene id: 1235441:CDO52_RS21480
uniprot id: A0A223SA78
names: Similarity
messages: Belongs to the GSP E family.

1235441:CDO52 RS24770
gene id: 1235441:CDO52_RS24770
uniprot id: A0A223SBZ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS01955
gene id: 1235441:CDO52_RS01955
uniprot id: A0A223S0S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1235441:CDO52 RS02110
gene id: 1235441:CDO52_RS02110
uniprot id: A0A223S0T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1235441:CDO52 RS23100
gene id: 1235441:CDO52_RS23100
uniprot id: A0A223SB95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1235441:CDO52 RS20350
gene id: 1235441:CDO52_RS20350
uniprot id: A0A223S9P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1235441:CDO52 RS09485
gene id: 1235441:CDO52_RS09485
uniprot id: A0A223S4E7
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1235441:CDO52 RS12675
gene id: 1235441:CDO52_RS12675
uniprot id: A0A223S5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1235441:CDO52 RS02825
gene id: 1235441:CDO52_RS02825
uniprot id: A0A223S162
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1235441:CDO52 RS09720
gene id: 1235441:CDO52_RS09720
uniprot id: A0A223S4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1235441:CDO52 RS08720
gene id: 1235441:CDO52_RS08720
uniprot id: A0A223S3Z8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS11360
gene id: 1235441:CDO52_RS11360
uniprot id: A0A223S595
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1235441:CDO52 RS17475
gene id: 1235441:CDO52_RS17475
uniprot id: A0A223S8B9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1235441:CDO52 RS21280
gene id: 1235441:CDO52_RS21280
uniprot id: A0A223SA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS23175
gene id: 1235441:CDO52_RS23175
uniprot id: A0A223SAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1235441:CDO52 RS11045
gene id: 1235441:CDO52_RS11045
uniprot id: A0A223S586
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS06610
gene id: 1235441:CDO52_RS06610
uniprot id: A0A223S2Z2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1235441:CDO52 RS22085
gene id: 1235441:CDO52_RS22085
uniprot id: A0A223SAR9
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1235441:CDO52 RS23405
gene id: 1235441:CDO52_RS23405
uniprot id: A0A223SB19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1235441:CDO52 RS12110
gene id: 1235441:CDO52_RS12110
uniprot id: A0A223S5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1235441:CDO52 RS26125
gene id: 1235441:CDO52_RS26125
uniprot id: A0A223SCK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS15570
gene id: 1235441:CDO52_RS15570
uniprot id: A0A223S7C4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS22515
gene id: 1235441:CDO52_RS22515
uniprot id: A0A223SAR8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1235441:CDO52 RS08390
gene id: 1235441:CDO52_RS08390
uniprot id: A0A223S3T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1235441:CDO52 RS06655
gene id: 1235441:CDO52_RS06655
uniprot id: A0A223S2Z0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS23770
gene id: 1235441:CDO52_RS23770
uniprot id: A0A223SBC8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1235441:CDO52 RS08120
gene id: 1235441:CDO52_RS08120
uniprot id: A0A223S3R4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1235441:CDO52 RS01550
gene id: 1235441:CDO52_RS01550
uniprot id: A0A223S0M3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1235441:CDO52 RS22780
gene id: 1235441:CDO52_RS22780
uniprot id: A0A223SAY2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1235441:CDO52 RS23035
gene id: 1235441:CDO52_RS23035
uniprot id: A0A223SAU4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1235441:CDO52 RS02715
gene id: 1235441:CDO52_RS02715
uniprot id: A0A223S148
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1235441:CDO52 RS16425
gene id: 1235441:CDO52_RS16425
uniprot id: A0A223S7S3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1235441:CDO52 RS24270
gene id: 1235441:CDO52_RS24270
uniprot id: A0A223SBN2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1235441:CDO52 RS22380
gene id: 1235441:CDO52_RS22380
uniprot id: A0A223SAX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1235441:CDO52 RS23230
gene id: 1235441:CDO52_RS23230
uniprot id: A0A223SB53
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1235441:CDO52 RS01940
gene id: 1235441:CDO52_RS01940
uniprot id: A0A223SD80
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS11795
gene id: 1235441:CDO52_RS11795
uniprot id: A0A223S5I1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS05585
gene id: 1235441:CDO52_RS05585
uniprot id: A0A223S2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS16770
gene id: 1235441:CDO52_RS16770
uniprot id: A0A223S7X8
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1235441:CDO52 RS11340
gene id: 1235441:CDO52_RS11340
uniprot id: A0A223S573
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1235441:CDO52 RS07630
gene id: 1235441:CDO52_RS07630
uniprot id: A0A223S3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS08730
gene id: 1235441:CDO52_RS08730
uniprot id: A0A223S3Z1
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1235441:CDO52 RS05740
gene id: 1235441:CDO52_RS05740
uniprot id: A0A223S2K3
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS19330
gene id: 1235441:CDO52_RS19330
uniprot id: A0A223S959
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1235441:CDO52 RS02105
gene id: 1235441:CDO52_RS02105
uniprot id: A0A223S0V9
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Belongs to the HIBADH-related family.

1235441:CDO52 RS23170
gene id: 1235441:CDO52_RS23170
uniprot id: A0A223SB63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1235441:CDO52 RS24990
gene id: 1235441:CDO52_RS24990
uniprot id: A0A223SC66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1235441:CDO52 RS15365
gene id: 1235441:CDO52_RS15365
uniprot id: A0A223S792
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1235441:CDO52 RS22095
gene id: 1235441:CDO52_RS22095
uniprot id: A0A223SAF2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1235441:CDO52 RS11555
gene id: 1235441:CDO52_RS11555
uniprot id: A0A223S5B0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1235441:CDO52 RS00545
gene id: 1235441:CDO52_RS00545
uniprot id: A0A223S048
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1235441:CDO52 RS06160
gene id: 1235441:CDO52_RS06160
uniprot id: A0A223SD32
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1235441:CDO52 RS19730
gene id: 1235441:CDO52_RS19730
uniprot id: A0A223S9E7
names: Similarity
messages: Belongs to the UPF0225 family.

1235441:CDO52 RS10405
gene id: 1235441:CDO52_RS10405
uniprot id: A0A223S4U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS12335
gene id: 1235441:CDO52_RS12335
uniprot id: A0A223S5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1235441:CDO52 RS10160
gene id: 1235441:CDO52_RS10160
uniprot id: A0A223S4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS01490
gene id: 1235441:CDO52_RS01490
uniprot id: A0A223S0H7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1235441:CDO52 RS02290
gene id: 1235441:CDO52_RS02290
uniprot id: A0A223S0V1
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS18120
gene id: 1235441:CDO52_RS18120
uniprot id: A0A223S8M2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1235441:CDO52 RS18300
gene id: 1235441:CDO52_RS18300
uniprot id: A0A223S8P9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1235441:CDO52 RS18995
gene id: 1235441:CDO52_RS18995
uniprot id: A0A223SDR8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1235441:CDO52 RS05220
gene id: 1235441:CDO52_RS05220
uniprot id: A0A223S2B7
names: Similarity
messages: Belongs to the citrate synthase family.

1235441:CDO52 RS03350
gene id: 1235441:CDO52_RS03350
uniprot id: A0A223S1D6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1235441:CDO52 RS04725
gene id: 1235441:CDO52_RS04725
uniprot id: A0A223S2D6
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

1235441:CDO52 RS22730
gene id: 1235441:CDO52_RS22730
uniprot id: A0A223SB32
names: Similarity
messages: Belongs to the peptidase S49 family.

1235441:CDO52 RS20180
gene id: 1235441:CDO52_RS20180
uniprot id: A0A223S9S2
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

1235441:CDO52 RS25190
gene id: 1235441:CDO52_RS25190
uniprot id: A0A223SC39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1235441:CDO52 RS11920
gene id: 1235441:CDO52_RS11920
uniprot id: A0A223S5H2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1235441:CDO52 RS17690
gene id: 1235441:CDO52_RS17690
uniprot id: A0A223S8D5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1235441:CDO52 RS00405
gene id: 1235441:CDO52_RS00405
uniprot id: A0A223SCZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1235441:CDO52 RS02080
gene id: 1235441:CDO52_RS02080
uniprot id: A0A223S137
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1235441:CDO52 RS01080
gene id: 1235441:CDO52_RS01080
uniprot id: A0A223S0C1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1235441:CDO52 RS21025
gene id: 1235441:CDO52_RS21025
uniprot id: A0A223S9Z4
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1235441:CDO52 RS17695
gene id: 1235441:CDO52_RS17695
uniprot id: A0A223S8D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1235441:CDO52 RS20140
gene id: 1235441:CDO52_RS20140
uniprot id: A0A223SDZ3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1235441:CDO52 RS01585
gene id: 1235441:CDO52_RS01585
uniprot id: A0A223S0L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1235441:CDO52 RS05025
gene id: 1235441:CDO52_RS05025
uniprot id: A0A223S2I4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1235441:CDO52 RS21990
gene id: 1235441:CDO52_RS21990
uniprot id: A0A223SAM3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1235441:CDO52 RS25275
gene id: 1235441:CDO52_RS25275
uniprot id: A0A223SC47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1235441:CDO52 RS04490
gene id: 1235441:CDO52_RS04490
uniprot id: A0A223S1Y0
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1235441:CDO52 RS09930
gene id: 1235441:CDO52_RS09930
uniprot id: A0A223S4Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1235441:CDO52 RS10770
gene id: 1235441:CDO52_RS10770
uniprot id: A0A223S504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1235441:CDO52 RS06770
gene id: 1235441:CDO52_RS06770
uniprot id: A0A223S310
names: Similarity
messages: Belongs to the FBPase class 2 family.

1235441:CDO52 RS09690
gene id: 1235441:CDO52_RS09690
uniprot id: A0A223S4R5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1235441:CDO52 RS09990
gene id: 1235441:CDO52_RS09990
uniprot id: A0A223S4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1235441:CDO52 RS14990
gene id: 1235441:CDO52_RS14990
uniprot id: A0A223S731
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1235441:CDO52 RS03780
gene id: 1235441:CDO52_RS03780
uniprot id: A0A223S1K9
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS10380
gene id: 1235441:CDO52_RS10380
uniprot id: A0A223S4S4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1235441:CDO52 RS13070
gene id: 1235441:CDO52_RS13070
uniprot id: A0A223SDG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1235441:CDO52 RS06315
gene id: 1235441:CDO52_RS06315
uniprot id: A0A223S2U3
names: Subcellular Location Annotation
messages: Cytoplasm

1235441:CDO52 RS10080
gene id: 1235441:CDO52_RS10080
uniprot id: A0A223SDE8
names: Similarity
messages: Belongs to the GroES chaperonin family.

1235441:CDO52 RS25045
gene id: 1235441:CDO52_RS25045
uniprot id: A0A223SBT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1235441:CDO52 RS24930
gene id: 1235441:CDO52_RS24930
uniprot id: A0A223SBR9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1235441:CDO52 RS11720
gene id: 1235441:CDO52_RS11720
uniprot id: A0A223S5E7
names: Similarity
messages: Belongs to the FGGY kinase family.

1235441:CDO52 RS11120
gene id: 1235441:CDO52_RS11120
uniprot id: A0A223S538
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

1235441:CDO52 RS14085
gene id: 1235441:CDO52_RS14085
uniprot id: A0A223S6L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS22040
gene id: 1235441:CDO52_RS22040
uniprot id: A0A223SAF6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1235441:CDO52 RS16680
gene id: 1235441:CDO52_RS16680
uniprot id: A0A223S7X4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS11310
gene id: 1235441:CDO52_RS11310
uniprot id: A0A223S580
names: Similarity
messages: Belongs to the SCO1/2 family.

1235441:CDO52 RS14950
gene id: 1235441:CDO52_RS14950
uniprot id: A0A223S728
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25530
gene id: 1235441:CDO52_RS25530
uniprot id: A0A223SC96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1235441:CDO52 RS17915
gene id: 1235441:CDO52_RS17915
uniprot id: A0A223S8L5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1235441:CDO52 RS22590
gene id: 1235441:CDO52_RS22590
uniprot id: A0A223SAT6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1235441:CDO52 RS20070
gene id: 1235441:CDO52_RS20070
uniprot id: A0A223S9K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS16505
gene id: 1235441:CDO52_RS16505
uniprot id: A0A223S7S8
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS12080
gene id: 1235441:CDO52_RS12080
uniprot id: A0A223S5W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS16285
gene id: 1235441:CDO52_RS16285
uniprot id: A0A223S7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS01690
gene id: 1235441:CDO52_RS01690
uniprot id: A0A223S0N7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS21430
gene id: 1235441:CDO52_RS21430
uniprot id: A0A223SA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1235441:CDO52 RS14160
gene id: 1235441:CDO52_RS14160
uniprot id: A0A223S6L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1235441:CDO52 RS04255
gene id: 1235441:CDO52_RS04255
uniprot id: A0A223S201
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1235441:CDO52 RS11480
gene id: 1235441:CDO52_RS11480
uniprot id: A0A223S598
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS06820
gene id: 1235441:CDO52_RS06820
uniprot id: A0A223S334
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1235441:CDO52 RS06585
gene id: 1235441:CDO52_RS06585
uniprot id: A0A223SD54
names: Cofactor
messages: Binds 1 FAD per subunit.

1235441:CDO52 RS25085
gene id: 1235441:CDO52_RS25085
uniprot id: A0A223SC19
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS01495
gene id: 1235441:CDO52_RS01495
uniprot id: A0A223S0I8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1235441:CDO52 RS00515
gene id: 1235441:CDO52_RS00515
uniprot id: A0A223S010
names: Similarity
messages: Belongs to the YciI family.

1235441:CDO52 RS02495
gene id: 1235441:CDO52_RS02495
uniprot id: A0A223S0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1235441:CDO52 RS15320
gene id: 1235441:CDO52_RS15320
uniprot id: A0A223S7A4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1235441:CDO52 RS09655
gene id: 1235441:CDO52_RS09655
uniprot id: A0A223S4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1235441:CDO52 RS04225
gene id: 1235441:CDO52_RS04225
uniprot id: A0A223S1U4
names: Similarity
messages: Belongs to the IMPACT family.

1235441:CDO52 RS21965
gene id: 1235441:CDO52_RS21965
uniprot id: A0A223SAE5
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS17665
gene id: 1235441:CDO52_RS17665
uniprot id: A0A223S8F1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1235441:CDO52 RS15070
gene id: 1235441:CDO52_RS15070
uniprot id: A0A223SDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1235441:CDO52 RS02250
gene id: 1235441:CDO52_RS02250
uniprot id: A0A223S0V2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1235441:CDO52 RS08965
gene id: 1235441:CDO52_RS08965
uniprot id: A0A223S432
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1235441:CDO52 RS23560
gene id: 1235441:CDO52_RS23560
uniprot id: A0A223SBD9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1235441:CDO52 RS16565
gene id: 1235441:CDO52_RS16565
uniprot id: A0A223S7S2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS23270
gene id: 1235441:CDO52_RS23270
uniprot id: A0A223SB48
names: Similarity
messages: Belongs to the thioesterase family.

1235441:CDO52 RS09500
gene id: 1235441:CDO52_RS09500
uniprot id: A0A223S4G6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1235441:CDO52 RS02330
gene id: 1235441:CDO52_RS02330
uniprot id: A0A223S179
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1235441:CDO52 RS01405
gene id: 1235441:CDO52_RS01405
uniprot id: A0A223S0I0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS19385
gene id: 1235441:CDO52_RS19385
uniprot id: A0A223S990
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1235441:CDO52 RS12415
gene id: 1235441:CDO52_RS12415
uniprot id: A0A223S612
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS24960
gene id: 1235441:CDO52_RS24960
uniprot id: A0A223SEB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1235441:CDO52 RS20435
gene id: 1235441:CDO52_RS20435
uniprot id: A0A223SE32
names: Similarity
messages: Belongs to the peptidase M1 family.

1235441:CDO52 RS09875
gene id: 1235441:CDO52_RS09875
uniprot id: A0A223S4L4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS00600
gene id: 1235441:CDO52_RS00600
uniprot id: A0A223S052
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1235441:CDO52 RS25100
gene id: 1235441:CDO52_RS25100
uniprot id: A0A223SBU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1235441:CDO52 RS12425
gene id: 1235441:CDO52_RS12425
uniprot id: A0A223S5T3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1235441:CDO52 RS16145
gene id: 1235441:CDO52_RS16145
uniprot id: A0A223S7S7
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS02930
gene id: 1235441:CDO52_RS02930
uniprot id: A0A223S1H6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1235441:CDO52 RS10935
gene id: 1235441:CDO52_RS10935
uniprot id: A0A223S566
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1235441:CDO52 RS11830
gene id: 1235441:CDO52_RS11830
uniprot id: A0A223S5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1235441:CDO52 RS22890
gene id: 1235441:CDO52_RS22890
uniprot id: A0A223SAX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1235441:CDO52 RS03035
gene id: 1235441:CDO52_RS03035
uniprot id: A0A223SD26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1235441:CDO52 RS16135
gene id: 1235441:CDO52_RS16135
uniprot id: A0A223S7N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1235441:CDO52 RS20205
gene id: 1235441:CDO52_RS20205
uniprot id: A0A223SE13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

1235441:CDO52 RS20690
gene id: 1235441:CDO52_RS20690
uniprot id: A0A223S9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1235441:CDO52 RS13175
gene id: 1235441:CDO52_RS13175
uniprot id: A0A223S661
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1235441:CDO52 RS11295
gene id: 1235441:CDO52_RS11295
uniprot id: A0A223S570
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS01675
gene id: 1235441:CDO52_RS01675
uniprot id: A0A223S0L1
names: Similarity
messages: Belongs to the proline racemase family.

1235441:CDO52 RS24955
gene id: 1235441:CDO52_RS24955
uniprot id: A0A223SC22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1235441:CDO52 RS02710
gene id: 1235441:CDO52_RS02710
uniprot id: A0A223S144
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1235441:CDO52 RS07550
gene id: 1235441:CDO52_RS07550
uniprot id: A0A223S3K6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1235441:CDO52 RS09445
gene id: 1235441:CDO52_RS09445
uniprot id: A0A223S4G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS13355
gene id: 1235441:CDO52_RS13355
uniprot id: A0A223S670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1235441:CDO52 RS03620
gene id: 1235441:CDO52_RS03620
uniprot id: A0A223S1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1235441:CDO52 RS21275
gene id: 1235441:CDO52_RS21275
uniprot id: A0A223SA29
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1235441:CDO52 RS06785
gene id: 1235441:CDO52_RS06785
uniprot id: A0A223S325
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1235441:CDO52 RS11765
gene id: 1235441:CDO52_RS11765
uniprot id: A0A223S5E9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1235441:CDO52 RS04535
gene id: 1235441:CDO52_RS04535
uniprot id: A0A223S1Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

1235441:CDO52 RS03280
gene id: 1235441:CDO52_RS03280
uniprot id: A0A223S1D2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1235441:CDO52 RS01115
gene id: 1235441:CDO52_RS01115
uniprot id: A0A223SD70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS26015
gene id: 1235441:CDO52_RS26015
uniprot id: A0A223SCI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS23145
gene id: 1235441:CDO52_RS23145
uniprot id: A0A223SAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1235441:CDO52 RS16030
gene id: 1235441:CDO52_RS16030
uniprot id: A0A223S7P3
names: Function
names: Similarity
messages: Belongs to the MerB family.
messages: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.

1235441:CDO52 RS25160
gene id: 1235441:CDO52_RS25160
uniprot id: A0A223SC98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1235441:CDO52 RS10135
gene id: 1235441:CDO52_RS10135
uniprot id: A0A223S4T6
names: Similarity
messages: Belongs to the CFA/CMAS family.

1235441:CDO52 RS08790
gene id: 1235441:CDO52_RS08790
uniprot id: A0A223S401
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1235441:CDO52 RS26150
gene id: 1235441:CDO52_RS26150
uniprot id: A0A223SCD9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1235441:CDO52 RS01025
gene id: 1235441:CDO52_RS01025
uniprot id: A0A223S0A3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1235441:CDO52 RS06410
gene id: 1235441:CDO52_RS06410
uniprot id: A0A223S2V8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS02100
gene id: 1235441:CDO52_RS02100
uniprot id: A0A223S0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1235441:CDO52 RS08955
gene id: 1235441:CDO52_RS08955
uniprot id: A0A223S437
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1235441:CDO52 RS25860
gene id: 1235441:CDO52_RS25860
uniprot id: A0A223SCE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1235441:CDO52 RS25215
gene id: 1235441:CDO52_RS25215
uniprot id: A0A223SC34
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1235441:CDO52 RS02960
gene id: 1235441:CDO52_RS02960
uniprot id: A0A223S181
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS07620
gene id: 1235441:CDO52_RS07620
uniprot id: A0A223S3G3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1235441:CDO52 RS11375
gene id: 1235441:CDO52_RS11375
uniprot id: A0A223S590
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1235441:CDO52 RS19580
gene id: 1235441:CDO52_RS19580
uniprot id: A0A223S9B1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS25435
gene id: 1235441:CDO52_RS25435
uniprot id: A0A223SC11
names: Similarity
messages: Belongs to the UPF0234 family.

1235441:CDO52 RS06425
gene id: 1235441:CDO52_RS06425
uniprot id: A0A223SD33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1235441:CDO52 RS23510
gene id: 1235441:CDO52_RS23510
uniprot id: A0A223SB97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1235441:CDO52 RS25110
gene id: 1235441:CDO52_RS25110
uniprot id: A0A223SC12
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1235441:CDO52 RS12175
gene id: 1235441:CDO52_RS12175
uniprot id: A0A223S5M2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS03945
gene id: 1235441:CDO52_RS03945
uniprot id: A0A223S1P5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1235441:CDO52 RS14470
gene id: 1235441:CDO52_RS14470
uniprot id: A0A223S6S9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1235441:CDO52 RS19560
gene id: 1235441:CDO52_RS19560
uniprot id: A0A223S9C0
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1235441:CDO52 RS11390
gene id: 1235441:CDO52_RS11390
uniprot id: A0A223SDE0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1235441:CDO52 RS17245
gene id: 1235441:CDO52_RS17245
uniprot id: A0A223SDV7
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1235441:CDO52 RS08990
gene id: 1235441:CDO52_RS08990
uniprot id: A0A223S441
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1235441:CDO52 RS15475
gene id: 1235441:CDO52_RS15475
uniprot id: A0A223S7A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1235441:CDO52 RS19895
gene id: 1235441:CDO52_RS19895
uniprot id: A0A223S9F2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1235441:CDO52 RS25960
gene id: 1235441:CDO52_RS25960
uniprot id: A0A223SCH4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1235441:CDO52 RS29060
gene id: 1235441:CDO52_RS29060
uniprot id: A0A223S283
names: Subcellular Location Annotation
messages: Cytoplasm

1235441:CDO52 RS10065
gene id: 1235441:CDO52_RS10065
uniprot id: A0A223S4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1235441:CDO52 RS22245
gene id: 1235441:CDO52_RS22245
uniprot id: A0A223SAI6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1235441:CDO52 RS23450
gene id: 1235441:CDO52_RS23450
uniprot id: A0A223SB86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1235441:CDO52 RS19445
gene id: 1235441:CDO52_RS19445
uniprot id: A0A223S9A5
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1235441:CDO52 RS05530
gene id: 1235441:CDO52_RS05530
uniprot id: A0A223S2G2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS12120
gene id: 1235441:CDO52_RS12120
uniprot id: A0A223S5L7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1235441:CDO52 RS23160
gene id: 1235441:CDO52_RS23160
uniprot id: A0A223SAV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1235441:CDO52 RS19620
gene id: 1235441:CDO52_RS19620
uniprot id: A0A223S9F0
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS05110
gene id: 1235441:CDO52_RS05110
uniprot id: A0A223S290
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1235441:CDO52 RS05500
gene id: 1235441:CDO52_RS05500
uniprot id: A0A223S2G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1235441:CDO52 RS22845
gene id: 1235441:CDO52_RS22845
uniprot id: A0A223SAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS18090
gene id: 1235441:CDO52_RS18090
uniprot id: A0A223S8J9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1235441:CDO52 RS11940
gene id: 1235441:CDO52_RS11940
uniprot id: A0A223S5I9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1235441:CDO52 RS20480
gene id: 1235441:CDO52_RS20480
uniprot id: A0A223S9S3
names: Similarity
messages: Belongs to the peptidase S9A family.

1235441:CDO52 RS18750
gene id: 1235441:CDO52_RS18750
uniprot id: A0A223S8X4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1235441:CDO52 RS11790
gene id: 1235441:CDO52_RS11790
uniprot id: A0A223S5K3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1235441:CDO52 RS25105
gene id: 1235441:CDO52_RS25105
uniprot id: A0A223SC88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1235441:CDO52 RS25070
gene id: 1235441:CDO52_RS25070
uniprot id: A0A223SC41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1235441:CDO52 RS07485
gene id: 1235441:CDO52_RS07485
uniprot id: A0A223S3E8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1235441:CDO52 RS04520
gene id: 1235441:CDO52_RS04520
uniprot id: A0A223S1Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1235441:CDO52 RS11450
gene id: 1235441:CDO52_RS11450
uniprot id: A0A223S588
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1235441:CDO52 RS08740
gene id: 1235441:CDO52_RS08740
uniprot id: A0A223S3Z3
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25230
gene id: 1235441:CDO52_RS25230
uniprot id: A0A223SC71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1235441:CDO52 RS21030
gene id: 1235441:CDO52_RS21030
uniprot id: A0A223SA23
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1235441:CDO52 RS12855
gene id: 1235441:CDO52_RS12855
uniprot id: A0A223S609
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1235441:CDO52 RS09710
gene id: 1235441:CDO52_RS09710
uniprot id: A0A223S4H5
names: Similarity
messages: Belongs to the peptidase M16 family.

1235441:CDO52 RS08750
gene id: 1235441:CDO52_RS08750
uniprot id: A0A223S413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1235441:CDO52 RS07565
gene id: 1235441:CDO52_RS07565
uniprot id: A0A223S3F4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS20665
gene id: 1235441:CDO52_RS20665
uniprot id: A0A223S9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS16200
gene id: 1235441:CDO52_RS16200
uniprot id: A0A223S7N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1235441:CDO52 RS08055
gene id: 1235441:CDO52_RS08055
uniprot id: A0A223SDF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1235441:CDO52 RS11785
gene id: 1235441:CDO52_RS11785
uniprot id: A0A223S5F2
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1235441:CDO52 RS03495
gene id: 1235441:CDO52_RS03495
uniprot id: A0A223S1J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1235441:CDO52 RS18035
gene id: 1235441:CDO52_RS18035
uniprot id: A0A223S8J4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS24730
gene id: 1235441:CDO52_RS24730
uniprot id: A0A223SE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS04905
gene id: 1235441:CDO52_RS04905
uniprot id: A0A223S237
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1235441:CDO52 RS16650
gene id: 1235441:CDO52_RS16650
uniprot id: A0A223S7V7
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1235441:CDO52 RS11710
gene id: 1235441:CDO52_RS11710
uniprot id: A0A223S5D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1235441:CDO52 RS06440
gene id: 1235441:CDO52_RS06440
uniprot id: A0A223S369
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1235441:CDO52 RS24500
gene id: 1235441:CDO52_RS24500
uniprot id: A0A223SBJ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1235441:CDO52 RS10475
gene id: 1235441:CDO52_RS10475
uniprot id: A0A223S4W0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1235441:CDO52 RS19355
gene id: 1235441:CDO52_RS19355
uniprot id: A0A223S9A7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1235441:CDO52 RS20540
gene id: 1235441:CDO52_RS20540
uniprot id: A0A223S9U0
names: Similarity
messages: Belongs to the CobH/CbiC family.

1235441:CDO52 RS03320
gene id: 1235441:CDO52_RS03320
uniprot id: A0A223S1F8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1235441:CDO52 RS06320
gene id: 1235441:CDO52_RS06320
uniprot id: A0A223SD44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1235441:CDO52 RS03360
gene id: 1235441:CDO52_RS03360
uniprot id: A0A223S1D3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1235441:CDO52 RS20425
gene id: 1235441:CDO52_RS20425
uniprot id: A0A223S9N3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS02350
gene id: 1235441:CDO52_RS02350
uniprot id: A0A223S0W5
names: Similarity
messages: Belongs to the WrbA family.

1235441:CDO52 RS03550
gene id: 1235441:CDO52_RS03550
uniprot id: A0A223S1K7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS12520
gene id: 1235441:CDO52_RS12520
uniprot id: A0A223S5V3
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1235441:CDO52 RS25920
gene id: 1235441:CDO52_RS25920
uniprot id: A0A223SCF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1235441:CDO52 RS17315
gene id: 1235441:CDO52_RS17315
uniprot id: A0A223S889
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1235441:CDO52 RS19185
gene id: 1235441:CDO52_RS19185
uniprot id: A0A223S976
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1235441:CDO52 RS25580
gene id: 1235441:CDO52_RS25580
uniprot id: A0A223SCA7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1235441:CDO52 RS25155
gene id: 1235441:CDO52_RS25155
uniprot id: A0A223SBV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1235441:CDO52 RS04260
gene id: 1235441:CDO52_RS04260
uniprot id: A0A223S1W1
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25305
gene id: 1235441:CDO52_RS25305
uniprot id: A0A223SBZ0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1235441:CDO52 RS20260
gene id: 1235441:CDO52_RS20260
uniprot id: A0A223S9N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1235441:CDO52 RS22120
gene id: 1235441:CDO52_RS22120
uniprot id: A0A223SAI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1235441:CDO52 RS26065
gene id: 1235441:CDO52_RS26065
uniprot id: A0A223SCH5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1235441:CDO52 RS06710
gene id: 1235441:CDO52_RS06710
uniprot id: A0A223S301
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1235441:CDO52 RS16935
gene id: 1235441:CDO52_RS16935
uniprot id: A0A223S848
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1235441:CDO52 RS01265
gene id: 1235441:CDO52_RS01265
uniprot id: A0A223S0E3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1235441:CDO52 RS11215
gene id: 1235441:CDO52_RS11215
uniprot id: A0A223S5H9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1235441:CDO52 RS12360
gene id: 1235441:CDO52_RS12360
uniprot id: A0A223S604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1235441:CDO52 RS25315
gene id: 1235441:CDO52_RS25315
uniprot id: A0A223SC52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1235441:CDO52 RS19285
gene id: 1235441:CDO52_RS19285
uniprot id: A0A223S962
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1235441:CDO52 RS09865
gene id: 1235441:CDO52_RS09865
uniprot id: A0A223S4H4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS10245
gene id: 1235441:CDO52_RS10245
uniprot id: A0A223S520
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1235441:CDO52 RS17265
gene id: 1235441:CDO52_RS17265
uniprot id: A0A223S897
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS04355
gene id: 1235441:CDO52_RS04355
uniprot id: A0A223S1V9
names: Similarity
messages: Belongs to the peptidase S8 family.

1235441:CDO52 RS04770
gene id: 1235441:CDO52_RS04770
uniprot id: A0A223S292
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1235441:CDO52 RS16205
gene id: 1235441:CDO52_RS16205
uniprot id: A0A223S7N2
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

1235441:CDO52 RS12460
gene id: 1235441:CDO52_RS12460
uniprot id: A0A223S5U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1235441:CDO52 RS25300
gene id: 1235441:CDO52_RS25300
uniprot id: A0A223SBZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1235441:CDO52 RS08975
gene id: 1235441:CDO52_RS08975
uniprot id: A0A223S453
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS12125
gene id: 1235441:CDO52_RS12125
uniprot id: A0A223S5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1235441:CDO52 RS11145
gene id: 1235441:CDO52_RS11145
uniprot id: A0A223S5A6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS08815
gene id: 1235441:CDO52_RS08815
uniprot id: A0A223S435
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1235441:CDO52 RS01670
gene id: 1235441:CDO52_RS01670
uniprot id: A0A223S0P5
names: Similarity
messages: Belongs to the DapA family.

1235441:CDO52 RS18190
gene id: 1235441:CDO52_RS18190
uniprot id: A0A223S8R6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1235441:CDO52 RS15860
gene id: 1235441:CDO52_RS15860
uniprot id: A0A223S7H5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS12465
gene id: 1235441:CDO52_RS12465
uniprot id: A0A223SDG8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1235441:CDO52 RS26100
gene id: 1235441:CDO52_RS26100
uniprot id: A0A223SCR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1235441:CDO52 RS25180
gene id: 1235441:CDO52_RS25180
uniprot id: A0A223SC61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1235441:CDO52 RS18410
gene id: 1235441:CDO52_RS18410
uniprot id: A0A223S8S3
names: Similarity
messages: Belongs to the LOR family.

1235441:CDO52 RS12255
gene id: 1235441:CDO52_RS12255
uniprot id: A0A223S5P0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS08275
gene id: 1235441:CDO52_RS08275
uniprot id: A0A223S3X0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1235441:CDO52 RS19235
gene id: 1235441:CDO52_RS19235
uniprot id: A0A223S967
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1235441:CDO52 RS10220
gene id: 1235441:CDO52_RS10220
uniprot id: A0A223S4P9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1235441:CDO52 RS25175
gene id: 1235441:CDO52_RS25175
uniprot id: A0A223SC24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1235441:CDO52 RS06575
gene id: 1235441:CDO52_RS06575
uniprot id: A0A223SDB6
names: Similarity
messages: Belongs to the CdaR family.

1235441:CDO52 RS17640
gene id: 1235441:CDO52_RS17640
uniprot id: A0A223S8C9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1235441:CDO52 RS18950
gene id: 1235441:CDO52_RS18950
uniprot id: A0A223S910
names: Similarity
messages: Belongs to the TlyA family.

1235441:CDO52 RS15400
gene id: 1235441:CDO52_RS15400
uniprot id: A0A223SDU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1235441:CDO52 RS17070
gene id: 1235441:CDO52_RS17070
uniprot id: A0A223S819
names: Similarity
messages: Belongs to the terpene synthase family.

1235441:CDO52 RS05490
gene id: 1235441:CDO52_RS05490
uniprot id: A0A223S2R2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1235441:CDO52 RS03535
gene id: 1235441:CDO52_RS03535
uniprot id: A0A223S1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS15705
gene id: 1235441:CDO52_RS15705
uniprot id: A0A223S7G8
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1235441:CDO52 RS17850
gene id: 1235441:CDO52_RS17850
uniprot id: A0A223S8H0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1235441:CDO52 RS06540
gene id: 1235441:CDO52_RS06540
uniprot id: A0A223S2Y5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1235441:CDO52 RS17395
gene id: 1235441:CDO52_RS17395
uniprot id: A0A223S888
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

1235441:CDO52 RS18940
gene id: 1235441:CDO52_RS18940
uniprot id: A0A223S928
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1235441:CDO52 RS05060
gene id: 1235441:CDO52_RS05060
uniprot id: A0A223S281
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS05020
gene id: 1235441:CDO52_RS05020
uniprot id: A0A223S288
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1235441:CDO52 RS04455
gene id: 1235441:CDO52_RS04455
uniprot id: A0A223S285
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1235441:CDO52 RS08515
gene id: 1235441:CDO52_RS08515
uniprot id: A0A223S3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS19120
gene id: 1235441:CDO52_RS19120
uniprot id: A0A223S931
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1235441:CDO52 RS09025
gene id: 1235441:CDO52_RS09025
uniprot id: A0A223S4A0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1235441:CDO52 RS21225
gene id: 1235441:CDO52_RS21225
uniprot id: A0A223SA93
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1235441:CDO52 RS02765
gene id: 1235441:CDO52_RS02765
uniprot id: A0A223S1E4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS13510
gene id: 1235441:CDO52_RS13510
uniprot id: A0A223S6D7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS05695
gene id: 1235441:CDO52_RS05695
uniprot id: A0A223S2I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1235441:CDO52 RS08650
gene id: 1235441:CDO52_RS08650
uniprot id: A0A223S488
names: Subcellular Location Annotation
messages: Cytoplasm

1235441:CDO52 RS02485
gene id: 1235441:CDO52_RS02485
uniprot id: A0A223S0Y3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1235441:CDO52 RS04310
gene id: 1235441:CDO52_RS04310
uniprot id: A0A223S211
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS01020
gene id: 1235441:CDO52_RS01020
uniprot id: A0A223S0B1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1235441:CDO52 RS22540
gene id: 1235441:CDO52_RS22540
uniprot id: A0A223SAP0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1235441:CDO52 RS22995
gene id: 1235441:CDO52_RS22995
uniprot id: A0A223SAZ3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1235441:CDO52 RS15005
gene id: 1235441:CDO52_RS15005
uniprot id: A0A223S729
names: Similarity
messages: Belongs to the arginase family.

1235441:CDO52 RS07650
gene id: 1235441:CDO52_RS07650
uniprot id: A0A223S3G2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS11330
gene id: 1235441:CDO52_RS11330
uniprot id: A0A223S597
names: Similarity
messages: Belongs to the AHA1 family.

1235441:CDO52 RS20090
gene id: 1235441:CDO52_RS20090
uniprot id: A0A223S9M6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1235441:CDO52 RS19190
gene id: 1235441:CDO52_RS19190
uniprot id: A0A223S943
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1235441:CDO52 RS20555
gene id: 1235441:CDO52_RS20555
uniprot id: A0A223S9Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1235441:CDO52 RS24185
gene id: 1235441:CDO52_RS24185
uniprot id: A0A223SBQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1235441:CDO52 RS25210
gene id: 1235441:CDO52_RS25210
uniprot id: A0A223SCB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1235441:CDO52 RS02045
gene id: 1235441:CDO52_RS02045
uniprot id: A0A223S0U9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1235441:CDO52 RS10375
gene id: 1235441:CDO52_RS10375
uniprot id: A0A223S4U8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1235441:CDO52 RS06715
gene id: 1235441:CDO52_RS06715
uniprot id: A0A223S302
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS15225
gene id: 1235441:CDO52_RS15225
uniprot id: A0A223S756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS16620
gene id: 1235441:CDO52_RS16620
uniprot id: A0A223S7U4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS14050
gene id: 1235441:CDO52_RS14050
uniprot id: A0A223S6K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1235441:CDO52 RS18645
gene id: 1235441:CDO52_RS18645
uniprot id: A0A223S8X8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1235441:CDO52 RS25440
gene id: 1235441:CDO52_RS25440
uniprot id: A0A223SCE7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS02815
gene id: 1235441:CDO52_RS02815
uniprot id: A0A223S163
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1235441:CDO52 RS09290
gene id: 1235441:CDO52_RS09290
uniprot id: A0A223S4B5
names: Similarity
messages: Belongs to the peptidase S13 family.

1235441:CDO52 RS09325
gene id: 1235441:CDO52_RS09325
uniprot id: A0A223S4A7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1235441:CDO52 RS12625
gene id: 1235441:CDO52_RS12625
uniprot id: A0A223S5Y6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS10275
gene id: 1235441:CDO52_RS10275
uniprot id: A0A223S4Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1235441:CDO52 RS21265
gene id: 1235441:CDO52_RS21265
uniprot id: A0A223SA50
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS20380
gene id: 1235441:CDO52_RS20380
uniprot id: A0A223SDV6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS16230
gene id: 1235441:CDO52_RS16230
uniprot id: A0A223S7L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1235441:CDO52 RS11815
gene id: 1235441:CDO52_RS11815
uniprot id: A0A223S5F7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS04065
gene id: 1235441:CDO52_RS04065
uniprot id: A0A223S1P4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS21100
gene id: 1235441:CDO52_RS21100
uniprot id: A0A223SA21
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1235441:CDO52 RS02700
gene id: 1235441:CDO52_RS02700
uniprot id: A0A223S142
names: Similarity
messages: Belongs to the CDPS family.

1235441:CDO52 RS02450
gene id: 1235441:CDO52_RS02450
uniprot id: A0A223S105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS21355
gene id: 1235441:CDO52_RS21355
uniprot id: A0A223SAA7
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1235441:CDO52 RS26320
gene id: 1235441:CDO52_RS26320
uniprot id: A0A223SE78
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS10905
gene id: 1235441:CDO52_RS10905
uniprot id: A0A223S512
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS14255
gene id: 1235441:CDO52_RS14255
uniprot id: A0A223S6Q1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS19090
gene id: 1235441:CDO52_RS19090
uniprot id: A0A223S921
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1235441:CDO52 RS25825
gene id: 1235441:CDO52_RS25825
uniprot id: A0A223SCG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1235441:CDO52 RS23165
gene id: 1235441:CDO52_RS23165
uniprot id: A0A223SB31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1235441:CDO52 RS12365
gene id: 1235441:CDO52_RS12365
uniprot id: A0A223S5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1235441:CDO52 RS05980
gene id: 1235441:CDO52_RS05980
uniprot id: A0A223S2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1235441:CDO52 RS24640
gene id: 1235441:CDO52_RS24640
uniprot id: A0A223SBT3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1235441:CDO52 RS10545
gene id: 1235441:CDO52_RS10545
uniprot id: A0A223S4X4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1235441:CDO52 RS13810
gene id: 1235441:CDO52_RS13810
uniprot id: A0A223S6G3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1235441:CDO52 RS11930
gene id: 1235441:CDO52_RS11930
uniprot id: A0A223S5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1235441:CDO52 RS25235
gene id: 1235441:CDO52_RS25235
uniprot id: A0A223SBX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1235441:CDO52 RS12550
gene id: 1235441:CDO52_RS12550
uniprot id: A0A223S5V6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS24840
gene id: 1235441:CDO52_RS24840
uniprot id: A0A223SBY0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1235441:CDO52 RS12050
gene id: 1235441:CDO52_RS12050
uniprot id: A0A223SDJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1235441:CDO52 RS17390
gene id: 1235441:CDO52_RS17390
uniprot id: A0A223S887
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS18270
gene id: 1235441:CDO52_RS18270
uniprot id: A0A223S8N6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1235441:CDO52 RS10790
gene id: 1235441:CDO52_RS10790
uniprot id: A0A223S4Z3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS05555
gene id: 1235441:CDO52_RS05555
uniprot id: A0A223S2F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS08215
gene id: 1235441:CDO52_RS08215
uniprot id: A0A223SD84
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1235441:CDO52 RS15335
gene id: 1235441:CDO52_RS15335
uniprot id: A0A223SDK9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1235441:CDO52 RS18740
gene id: 1235441:CDO52_RS18740
uniprot id: A0A223S8W9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS23745
gene id: 1235441:CDO52_RS23745
uniprot id: A0A223SBD6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1235441:CDO52 RS01580
gene id: 1235441:CDO52_RS01580
uniprot id: A0A223S0W6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1235441:CDO52 RS25730
gene id: 1235441:CDO52_RS25730
uniprot id: A0A223SCC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS22550
gene id: 1235441:CDO52_RS22550
uniprot id: A0A223SB03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1235441:CDO52 RS06240
gene id: 1235441:CDO52_RS06240
uniprot id: A0A223S339
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1235441:CDO52 RS23200
gene id: 1235441:CDO52_RS23200
uniprot id: A0A223SBB4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1235441:CDO52 RS15025
gene id: 1235441:CDO52_RS15025
uniprot id: A0A223SDL5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1235441:CDO52 RS22570
gene id: 1235441:CDO52_RS22570
uniprot id: A0A223SAS7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1235441:CDO52 RS06620
gene id: 1235441:CDO52_RS06620
uniprot id: A0A223S348
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1235441:CDO52 RS08885
gene id: 1235441:CDO52_RS08885
uniprot id: A0A223S429
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1235441:CDO52 RS05475
gene id: 1235441:CDO52_RS05475
uniprot id: A0A223S2F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1235441:CDO52 RS25220
gene id: 1235441:CDO52_RS25220
uniprot id: A0A223SBV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1235441:CDO52 RS11910
gene id: 1235441:CDO52_RS11910
uniprot id: A0A223S5H1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1235441:CDO52 RS25240
gene id: 1235441:CDO52_RS25240
uniprot id: A0A223SC45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1235441:CDO52 RS20125
gene id: 1235441:CDO52_RS20125
uniprot id: A0A223S9J9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1235441:CDO52 RS20120
gene id: 1235441:CDO52_RS20120
uniprot id: A0A223SDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS06255
gene id: 1235441:CDO52_RS06255
uniprot id: A0A223S2T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1235441:CDO52 RS20695
gene id: 1235441:CDO52_RS20695
uniprot id: A0A223S9S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1235441:CDO52 RS20290
gene id: 1235441:CDO52_RS20290
uniprot id: A0A223S9Q4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS04395
gene id: 1235441:CDO52_RS04395
uniprot id: A0A223S1V7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS03865
gene id: 1235441:CDO52_RS03865
uniprot id: A0A223S1N6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1235441:CDO52 RS10015
gene id: 1235441:CDO52_RS10015
uniprot id: A0A223S4X7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1235441:CDO52 RS14425
gene id: 1235441:CDO52_RS14425
uniprot id: A0A223S6S2
names: Similarity
messages: Belongs to the peptidase S1 family.

1235441:CDO52 RS13865
gene id: 1235441:CDO52_RS13865
uniprot id: A0A223S6I7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1235441:CDO52 RS19290
gene id: 1235441:CDO52_RS19290
uniprot id: A0A223S964
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1235441:CDO52 RS07660
gene id: 1235441:CDO52_RS07660
uniprot id: A0A223S3I1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1235441:CDO52 RS15495
gene id: 1235441:CDO52_RS15495
uniprot id: A0A223S799
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1235441:CDO52 RS20250
gene id: 1235441:CDO52_RS20250
uniprot id: A0A223S9T1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1235441:CDO52 RS11380
gene id: 1235441:CDO52_RS11380
uniprot id: A0A223S594
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1235441:CDO52 RS23150
gene id: 1235441:CDO52_RS23150
uniprot id: A0A223SBA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1235441:CDO52 RS04265
gene id: 1235441:CDO52_RS04265
uniprot id: A0A223S256
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS13775
gene id: 1235441:CDO52_RS13775
uniprot id: A0A223S6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1235441:CDO52 RS19860
gene id: 1235441:CDO52_RS19860
uniprot id: A0A223S9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS08315
gene id: 1235441:CDO52_RS08315
uniprot id: A0A223S3U4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1235441:CDO52 RS24905
gene id: 1235441:CDO52_RS24905
uniprot id: A0A223SBR4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS03225
gene id: 1235441:CDO52_RS03225
uniprot id: A0A223S1C5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1235441:CDO52 RS02055
gene id: 1235441:CDO52_RS02055
uniprot id: A0A223S0U3
names: Similarity
messages: Belongs to the ParB family.

1235441:CDO52 RS18330
gene id: 1235441:CDO52_RS18330
uniprot id: A0A223S8S0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1235441:CDO52 RS02605
gene id: 1235441:CDO52_RS02605
uniprot id: A0A223S125
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1235441:CDO52 RS19300
gene id: 1235441:CDO52_RS19300
uniprot id: A0A223S997
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1235441:CDO52 RS11085
gene id: 1235441:CDO52_RS11085
uniprot id: A0A223S547
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1235441:CDO52 RS15530
gene id: 1235441:CDO52_RS15530
uniprot id: A0A223S7B1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1235441:CDO52 RS24350
gene id: 1235441:CDO52_RS24350
uniprot id: A0A223SBW2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1235441:CDO52 RS08395
gene id: 1235441:CDO52_RS08395
uniprot id: A0A223S3U8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1235441:CDO52 RS28835
gene id: 1235441:CDO52_RS28835
uniprot id: A0A223S8H5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

1235441:CDO52 RS10720
gene id: 1235441:CDO52_RS10720
uniprot id: A0A223S503
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1235441:CDO52 RS19160
gene id: 1235441:CDO52_RS19160
uniprot id: A0A223S934
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS13930
gene id: 1235441:CDO52_RS13930
uniprot id: A0A223S6J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1235441:CDO52 RS05810
gene id: 1235441:CDO52_RS05810
uniprot id: A0A223SD78
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1235441:CDO52 RS22520
gene id: 1235441:CDO52_RS22520
uniprot id: A0A223SAV1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS17885
gene id: 1235441:CDO52_RS17885
uniprot id: A0A223S8J1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS08085
gene id: 1235441:CDO52_RS08085
uniprot id: A0A223S3P8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1235441:CDO52 RS07890
gene id: 1235441:CDO52_RS07890
uniprot id: A0A223S3K9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1235441:CDO52 RS26340
gene id: 1235441:CDO52_RS26340
uniprot id: A0A223SCV5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1235441:CDO52 RS09105
gene id: 1235441:CDO52_RS09105
uniprot id: A0A223S469
names: Similarity
messages: Belongs to the threonine aldolase family.

1235441:CDO52 RS12005
gene id: 1235441:CDO52_RS12005
uniprot id: A0A223S5J5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1235441:CDO52 RS09440
gene id: 1235441:CDO52_RS09440
uniprot id: A0A223S4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS20345
gene id: 1235441:CDO52_RS20345
uniprot id: A0A223S9R3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1235441:CDO52 RS22260
gene id: 1235441:CDO52_RS22260
uniprot id: A0A223SAK1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1235441:CDO52 RS01965
gene id: 1235441:CDO52_RS01965
uniprot id: A0A223S0Q5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1235441:CDO52 RS11135
gene id: 1235441:CDO52_RS11135
uniprot id: A0A223S556
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS24545
gene id: 1235441:CDO52_RS24545
uniprot id: A0A223SBS3
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS07905
gene id: 1235441:CDO52_RS07905
uniprot id: A0A223S3L8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1235441:CDO52 RS21050
gene id: 1235441:CDO52_RS21050
uniprot id: A0A223SA11
names: Similarity
messages: Belongs to the XFP family.

1235441:CDO52 RS11025
gene id: 1235441:CDO52_RS11025
uniprot id: A0A223S534
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1235441:CDO52 RS25330
gene id: 1235441:CDO52_RS25330
uniprot id: A0A223SBY7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1235441:CDO52 RS04105
gene id: 1235441:CDO52_RS04105
uniprot id: A0A223S1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1235441:CDO52 RS02940
gene id: 1235441:CDO52_RS02940
uniprot id: A0A223S187
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1235441:CDO52 RS20355
gene id: 1235441:CDO52_RS20355
uniprot id: A0A223S9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1235441:CDO52 RS05780
gene id: 1235441:CDO52_RS05780
uniprot id: A0A223S2K6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1235441:CDO52 RS10635
gene id: 1235441:CDO52_RS10635
uniprot id: A0A223S4Y8
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS18365
gene id: 1235441:CDO52_RS18365
uniprot id: A0A223S8Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS19115
gene id: 1235441:CDO52_RS19115
uniprot id: A0A223S923
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS11100
gene id: 1235441:CDO52_RS11100
uniprot id: A0A223S559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS25310
gene id: 1235441:CDO52_RS25310
uniprot id: A0A223SCD0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1235441:CDO52 RS18855
gene id: 1235441:CDO52_RS18855
uniprot id: A0A223S8Y4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1235441:CDO52 RS25055
gene id: 1235441:CDO52_RS25055
uniprot id: A0A223SC05
names: Similarity
messages: Belongs to the peptidase M1 family.

1235441:CDO52 RS02260
gene id: 1235441:CDO52_RS02260
uniprot id: A0A223S100
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1235441:CDO52 RS11820
gene id: 1235441:CDO52_RS11820
uniprot id: A0A223S5H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1235441:CDO52 RS25645
gene id: 1235441:CDO52_RS25645
uniprot id: A0A223SCC6
names: Cofactor
messages: Binds 1 FAD per subunit.

1235441:CDO52 RS12390
gene id: 1235441:CDO52_RS12390
uniprot id: A0A223S5T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1235441:CDO52 RS01610
gene id: 1235441:CDO52_RS01610
uniprot id: A0A223S0K1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1235441:CDO52 RS20520
gene id: 1235441:CDO52_RS20520
uniprot id: A0A223S9R6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1235441:CDO52 RS16685
gene id: 1235441:CDO52_RS16685
uniprot id: A0A223S7W7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS15640
gene id: 1235441:CDO52_RS15640
uniprot id: A0A223S7D2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS25965
gene id: 1235441:CDO52_RS25965
uniprot id: A0A223SCH6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1235441:CDO52 RS04155
gene id: 1235441:CDO52_RS04155
uniprot id: A0A223S1S9
names: Similarity
messages: Belongs to the RutC family.

1235441:CDO52 RS05190
gene id: 1235441:CDO52_RS05190
uniprot id: A0A223SDA1
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS04570
gene id: 1235441:CDO52_RS04570
uniprot id: A0A223S204
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1235441:CDO52 RS04110
gene id: 1235441:CDO52_RS04110
uniprot id: A0A223S1S2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1235441:CDO52 RS19550
gene id: 1235441:CDO52_RS19550
uniprot id: A0A223S9B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1235441:CDO52 RS23420
gene id: 1235441:CDO52_RS23420
uniprot id: A0A223SBF7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1235441:CDO52 RS01950
gene id: 1235441:CDO52_RS01950
uniprot id: A0A223S120
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1235441:CDO52 RS14875
gene id: 1235441:CDO52_RS14875
uniprot id: A0A223SDJ9
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS26635
gene id: 1235441:CDO52_RS26635
uniprot id: A0A223SCM2
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS09970
gene id: 1235441:CDO52_RS09970
uniprot id: A0A223SDC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1235441:CDO52 RS18605
gene id: 1235441:CDO52_RS18605
uniprot id: A0A223SDU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1235441:CDO52 RS05335
gene id: 1235441:CDO52_RS05335
uniprot id: A0A223SD88
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1235441:CDO52 RS24110
gene id: 1235441:CDO52_RS24110
uniprot id: A0A223SBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1235441:CDO52 RS20270
gene id: 1235441:CDO52_RS20270
uniprot id: A0A223S9L2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1235441:CDO52 RS09820
gene id: 1235441:CDO52_RS09820
uniprot id: A0A223S4V2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1235441:CDO52 RS21250
gene id: 1235441:CDO52_RS21250
uniprot id: A0A223SA37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1235441:CDO52 RS10900
gene id: 1235441:CDO52_RS10900
uniprot id: A0A223S4Z6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1235441:CDO52 RS12380
gene id: 1235441:CDO52_RS12380
uniprot id: A0A223S5R7
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS15310
gene id: 1235441:CDO52_RS15310
uniprot id: A0A223S771
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1235441:CDO52 RS25500
gene id: 1235441:CDO52_RS25500
uniprot id: A0A223SC16
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1235441:CDO52 RS13035
gene id: 1235441:CDO52_RS13035
uniprot id: A0A223S657
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1235441:CDO52 RS16155
gene id: 1235441:CDO52_RS16155
uniprot id: A0A223S7L7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1235441:CDO52 RS20420
gene id: 1235441:CDO52_RS20420
uniprot id: A0A223S9R4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1235441:CDO52 RS13230
gene id: 1235441:CDO52_RS13230
uniprot id: A0A223S674
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1235441:CDO52 RS09705
gene id: 1235441:CDO52_RS09705
uniprot id: A0A223S4H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1235441:CDO52 RS05230
gene id: 1235441:CDO52_RS05230
uniprot id: A0A223S2B0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1235441:CDO52 RS17285
gene id: 1235441:CDO52_RS17285
uniprot id: A0A223S869
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS04580
gene id: 1235441:CDO52_RS04580
uniprot id: A0A223S203
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1235441:CDO52 RS08375
gene id: 1235441:CDO52_RS08375
uniprot id: A0A223S3V4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1235441:CDO52 RS06250
gene id: 1235441:CDO52_RS06250
uniprot id: A0A223S2U5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1235441:CDO52 RS09205
gene id: 1235441:CDO52_RS09205
uniprot id: A0A223S487
names: Similarity
messages: Belongs to the DprA/Smf family.

1235441:CDO52 RS17480
gene id: 1235441:CDO52_RS17480
uniprot id: A0A223S8D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1235441:CDO52 RS19765
gene id: 1235441:CDO52_RS19765
uniprot id: A0A223S9F5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1235441:CDO52 RS20175
gene id: 1235441:CDO52_RS20175
uniprot id: A0A223S9J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1235441:CDO52 RS14825
gene id: 1235441:CDO52_RS14825
uniprot id: A0A223S6Z3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1235441:CDO52 RS04585
gene id: 1235441:CDO52_RS04585
uniprot id: A0A223S207
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1235441:CDO52 RS23565
gene id: 1235441:CDO52_RS23565
uniprot id: A0A223SB27
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

1235441:CDO52 RS07645
gene id: 1235441:CDO52_RS07645
uniprot id: A0A223S3H9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1235441:CDO52 RS25540
gene id: 1235441:CDO52_RS25540
uniprot id: A0A223SC37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1235441:CDO52 RS18850
gene id: 1235441:CDO52_RS18850
uniprot id: A0A223S905
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1235441:CDO52 RS06420
gene id: 1235441:CDO52_RS06420
uniprot id: A0A223S318
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1235441:CDO52 RS25025
gene id: 1235441:CDO52_RS25025
uniprot id: A0A223SC06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS21160
gene id: 1235441:CDO52_RS21160
uniprot id: A0A223SA32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1235441:CDO52 RS08405
gene id: 1235441:CDO52_RS08405
uniprot id: A0A223S3Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1235441:CDO52 RS19135
gene id: 1235441:CDO52_RS19135
uniprot id: A0A223S965
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1235441:CDO52 RS25145
gene id: 1235441:CDO52_RS25145
uniprot id: A0A223SC36
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1235441:CDO52 RS18680
gene id: 1235441:CDO52_RS18680
uniprot id: A0A223S8W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS14095
gene id: 1235441:CDO52_RS14095
uniprot id: A0A223S6K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS03355
gene id: 1235441:CDO52_RS03355
uniprot id: A0A223S1E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1235441:CDO52 RS23155
gene id: 1235441:CDO52_RS23155
uniprot id: A0A223SB24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1235441:CDO52 RS07055
gene id: 1235441:CDO52_RS07055
uniprot id: A0A223S374
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1235441:CDO52 RS10875
gene id: 1235441:CDO52_RS10875
uniprot id: A0A223S523
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS04405
gene id: 1235441:CDO52_RS04405
uniprot id: A0A223S1V6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS24655
gene id: 1235441:CDO52_RS24655
uniprot id: A0A223SBM4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1235441:CDO52 RS13965
gene id: 1235441:CDO52_RS13965
uniprot id: A0A223S6R8
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS06600
gene id: 1235441:CDO52_RS06600
uniprot id: A0A223S2Y6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1235441:CDO52 RS03520
gene id: 1235441:CDO52_RS03520
uniprot id: A0A223S1G1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1235441:CDO52 RS22645
gene id: 1235441:CDO52_RS22645
uniprot id: A0A223SAP4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1235441:CDO52 RS02600
gene id: 1235441:CDO52_RS02600
uniprot id: A0A223SCW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1235441:CDO52 RS01935
gene id: 1235441:CDO52_RS01935
uniprot id: A0A223S0U7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1235441:CDO52 RS13720
gene id: 1235441:CDO52_RS13720
uniprot id: A0A223S6E5
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1235441:CDO52 RS20235
gene id: 1235441:CDO52_RS20235
uniprot id: A0A223S9M9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1235441:CDO52 RS17740
gene id: 1235441:CDO52_RS17740
uniprot id: A0A223S8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS18910
gene id: 1235441:CDO52_RS18910
uniprot id: A0A223S915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1235441:CDO52 RS22190
gene id: 1235441:CDO52_RS22190
uniprot id: A0A223SAI8
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1235441:CDO52 RS06685
gene id: 1235441:CDO52_RS06685
uniprot id: A0A223S358
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1235441:CDO52 RS04575
gene id: 1235441:CDO52_RS04575
uniprot id: A0A223S1Y1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1235441:CDO52 RS26515
gene id: 1235441:CDO52_RS26515
uniprot id: A0A223SCK4
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS20965
gene id: 1235441:CDO52_RS20965
uniprot id: A0A223S9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

1235441:CDO52 RS07255
gene id: 1235441:CDO52_RS07255
uniprot id: A0A223SD69
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1235441:CDO52 RS17830
gene id: 1235441:CDO52_RS17830
uniprot id: A0A223S8G2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1235441:CDO52 RS09080
gene id: 1235441:CDO52_RS09080
uniprot id: A0A223S472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS19140
gene id: 1235441:CDO52_RS19140
uniprot id: A0A223S933
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1235441:CDO52 RS26955
gene id: 1235441:CDO52_RS26955
uniprot id: A0A223SCY1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1235441:CDO52 RS26605
gene id: 1235441:CDO52_RS26605
uniprot id: A0A223SCT8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS08460
gene id: 1235441:CDO52_RS08460
uniprot id: A0A223SD79
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1235441:CDO52 RS25790
gene id: 1235441:CDO52_RS25790
uniprot id: A0A223SC78
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1235441:CDO52 RS18700
gene id: 1235441:CDO52_RS18700
uniprot id: A0A223S8Y8
names: Similarity
messages: Belongs to the arginine deiminase family.

1235441:CDO52 RS13490
gene id: 1235441:CDO52_RS13490
uniprot id: A0A223S698
names: Cofactor
messages: Can also use Mn(2+) ion.

1235441:CDO52 RS15200
gene id: 1235441:CDO52_RS15200
uniprot id: A0A223S757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1235441:CDO52 RS11865
gene id: 1235441:CDO52_RS11865
uniprot id: A0A223S5G7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1235441:CDO52 RS09430
gene id: 1235441:CDO52_RS09430
uniprot id: A0A223S4D6
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

1235441:CDO52 RS21135
gene id: 1235441:CDO52_RS21135
uniprot id: A0A223SA48
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS01110
gene id: 1235441:CDO52_RS01110
uniprot id: A0A223S0F4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1235441:CDO52 RS07580
gene id: 1235441:CDO52_RS07580
uniprot id: A0A223S3F7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1235441:CDO52 RS13820
gene id: 1235441:CDO52_RS13820
uniprot id: A0A223S6G2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS12190
gene id: 1235441:CDO52_RS12190
uniprot id: A0A223S5P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1235441:CDO52 RS03045
gene id: 1235441:CDO52_RS03045
uniprot id: A0A223SD30
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS13725
gene id: 1235441:CDO52_RS13725
uniprot id: A0A223S6G5
names: Similarity
messages: Belongs to the peptidase S1 family.

1235441:CDO52 RS09395
gene id: 1235441:CDO52_RS09395
uniprot id: A0A223S4B7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1235441:CDO52 RS05000
gene id: 1235441:CDO52_RS05000
uniprot id: A0A223S274
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1235441:CDO52 RS00410
gene id: 1235441:CDO52_RS00410
uniprot id: A0A223RZX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1235441:CDO52 RS05495
gene id: 1235441:CDO52_RS05495
uniprot id: A0A223S2E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1235441:CDO52 RS08825
gene id: 1235441:CDO52_RS08825
uniprot id: A0A223S420
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1235441:CDO52 RS16790
gene id: 1235441:CDO52_RS16790
uniprot id: A0A223S7Z3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1235441:CDO52 RS04250
gene id: 1235441:CDO52_RS04250
uniprot id: A0A223S1T9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1235441:CDO52 RS22385
gene id: 1235441:CDO52_RS22385
uniprot id: A0A223SAK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1235441:CDO52 RS24880
gene id: 1235441:CDO52_RS24880
uniprot id: A0A223SC44
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS11515
gene id: 1235441:CDO52_RS11515
uniprot id: A0A223S5L6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS18900
gene id: 1235441:CDO52_RS18900
uniprot id: A0A223S8Z6
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS20660
gene id: 1235441:CDO52_RS20660
uniprot id: A0A223S9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS13565
gene id: 1235441:CDO52_RS13565
uniprot id: A0A223S6A8
names: Similarity
messages: Belongs to the AHA1 family.

1235441:CDO52 RS03565
gene id: 1235441:CDO52_RS03565
uniprot id: A0A223S1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS12685
gene id: 1235441:CDO52_RS12685
uniprot id: A0A223S5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1235441:CDO52 RS17440
gene id: 1235441:CDO52_RS17440
uniprot id: A0A223S893
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS25165
gene id: 1235441:CDO52_RS25165
uniprot id: A0A223SC27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1235441:CDO52 RS26580
gene id: 1235441:CDO52_RS26580
uniprot id: A0A223SCZ1
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS14570
gene id: 1235441:CDO52_RS14570
uniprot id: A0A223S6W5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1235441:CDO52 RS09860
gene id: 1235441:CDO52_RS09860
uniprot id: A0A223S4K3
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1235441:CDO52 RS25255
gene id: 1235441:CDO52_RS25255
uniprot id: A0A223SBY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1235441:CDO52 RS03610
gene id: 1235441:CDO52_RS03610
uniprot id: A0A223S1L6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1235441:CDO52 RS11275
gene id: 1235441:CDO52_RS11275
uniprot id: A0A223S587
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1235441:CDO52 RS23305
gene id: 1235441:CDO52_RS23305
uniprot id: A0A223SAZ4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1235441:CDO52 RS03415
gene id: 1235441:CDO52_RS03415
uniprot id: A0A223S1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1235441:CDO52 RS03600
gene id: 1235441:CDO52_RS03600
uniprot id: A0A223S1H5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1235441:CDO52 RS25135
gene id: 1235441:CDO52_RS25135
uniprot id: A0A223SBV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1235441:CDO52 RS05690
gene id: 1235441:CDO52_RS05690
uniprot id: A0A223S2J2
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1235441:CDO52 RS14905
gene id: 1235441:CDO52_RS14905
uniprot id: A0A223S703
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1235441:CDO52 RS24605
gene id: 1235441:CDO52_RS24605
uniprot id: A0A223SBU4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1235441:CDO52 RS01280
gene id: 1235441:CDO52_RS01280
uniprot id: A0A223S0H8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1235441:CDO52 RS23570
gene id: 1235441:CDO52_RS23570
uniprot id: A0A223SBA9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1235441:CDO52 RS02035
gene id: 1235441:CDO52_RS02035
uniprot id: A0A223S0R5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1235441:CDO52 RS04695
gene id: 1235441:CDO52_RS04695
uniprot id: A0A223S218
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1235441:CDO52 RS22680
gene id: 1235441:CDO52_RS22680
uniprot id: A0A223SAU1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1235441:CDO52 RS10400
gene id: 1235441:CDO52_RS10400
uniprot id: A0A223S4T3
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS19845
gene id: 1235441:CDO52_RS19845
uniprot id: A0A223S9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS02780
gene id: 1235441:CDO52_RS02780
uniprot id: A0A223S140
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1235441:CDO52 RS20600
gene id: 1235441:CDO52_RS20600
uniprot id: A0A223S9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS04960
gene id: 1235441:CDO52_RS04960
uniprot id: A0A223S2H4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1235441:CDO52 RS09910
gene id: 1235441:CDO52_RS09910
uniprot id: A0A223S4K0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1235441:CDO52 RS23330
gene id: 1235441:CDO52_RS23330
uniprot id: A0A223SB93
names: Similarity
messages: Belongs to the peptidase S33 family.

1235441:CDO52 RS12580
gene id: 1235441:CDO52_RS12580
uniprot id: A0A223S5V9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1235441:CDO52 RS07545
gene id: 1235441:CDO52_RS07545
uniprot id: A0A223S3E2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1235441:CDO52 RS08805
gene id: 1235441:CDO52_RS08805
uniprot id: A0A223S4C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1235441:CDO52 RS09335
gene id: 1235441:CDO52_RS09335
uniprot id: A0A223SDA6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1235441:CDO52 RS17820
gene id: 1235441:CDO52_RS17820
uniprot id: A0A223S8F6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1235441:CDO52 RS08565
gene id: 1235441:CDO52_RS08565
uniprot id: A0A223S3W2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1235441:CDO52 RS11460
gene id: 1235441:CDO52_RS11460
uniprot id: A0A223S5B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1235441:CDO52 RS02345
gene id: 1235441:CDO52_RS02345
uniprot id: A0A223S0W1
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS23980
gene id: 1235441:CDO52_RS23980
uniprot id: A0A223SBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1235441:CDO52 RS00450
gene id: 1235441:CDO52_RS00450
uniprot id: A0A223S022
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS11470
gene id: 1235441:CDO52_RS11470
uniprot id: A0A223S593
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1235441:CDO52 RS24480
gene id: 1235441:CDO52_RS24480
uniprot id: A0A223SBJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1235441:CDO52 RS17250
gene id: 1235441:CDO52_RS17250
uniprot id: A0A223S870
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1235441:CDO52 RS20265
gene id: 1235441:CDO52_RS20265
uniprot id: A0A223S9Q8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1235441:CDO52 RS13455
gene id: 1235441:CDO52_RS13455
uniprot id: A0A223S6C7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1235441:CDO52 RS20710
gene id: 1235441:CDO52_RS20710
uniprot id: A0A223S9T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1235441:CDO52 RS20780
gene id: 1235441:CDO52_RS20780
uniprot id: A0A223S9V5
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS11840
gene id: 1235441:CDO52_RS11840
uniprot id: A0A223S5L1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS04030
gene id: 1235441:CDO52_RS04030
uniprot id: A0A223S1V8
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS05245
gene id: 1235441:CDO52_RS05245
uniprot id: A0A223S2M0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS25205
gene id: 1235441:CDO52_RS25205
uniprot id: A0A223SBX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1235441:CDO52 RS18615
gene id: 1235441:CDO52_RS18615
uniprot id: A0A223S8V6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1235441:CDO52 RS03515
gene id: 1235441:CDO52_RS03515
uniprot id: A0A223S1H2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1235441:CDO52 RS12010
gene id: 1235441:CDO52_RS12010
uniprot id: A0A223S5N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1235441:CDO52 RS21215
gene id: 1235441:CDO52_RS21215
uniprot id: A0A223SA15
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS01125
gene id: 1235441:CDO52_RS01125
uniprot id: A0A223S0N2
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1235441:CDO52 RS22610
gene id: 1235441:CDO52_RS22610
uniprot id: A0A223SAP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1235441:CDO52 RS06075
gene id: 1235441:CDO52_RS06075
uniprot id: A0A223S2R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1235441:CDO52 RS12600
gene id: 1235441:CDO52_RS12600
uniprot id: A0A223S5W0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1235441:CDO52 RS02085
gene id: 1235441:CDO52_RS02085
uniprot id: A0A223S0U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1235441:CDO52 RS04240
gene id: 1235441:CDO52_RS04240
uniprot id: A0A223S1V3
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1235441:CDO52 RS24180
gene id: 1235441:CDO52_RS24180
uniprot id: A0A223SBK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1235441:CDO52 RS11810
gene id: 1235441:CDO52_RS11810
uniprot id: A0A223S5I4
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1235441:CDO52 RS05195
gene id: 1235441:CDO52_RS05195
uniprot id: A0A223S2L2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1235441:CDO52 RS17735
gene id: 1235441:CDO52_RS17735
uniprot id: A0A223S8F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS08840
gene id: 1235441:CDO52_RS08840
uniprot id: A0A223S425
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1235441:CDO52 RS08880
gene id: 1235441:CDO52_RS08880
uniprot id: A0A223S431
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1235441:CDO52 RS04710
gene id: 1235441:CDO52_RS04710
uniprot id: A0A223S282
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1235441:CDO52 RS08010
gene id: 1235441:CDO52_RS08010
uniprot id: A0A223S3P6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1235441:CDO52 RS20405
gene id: 1235441:CDO52_RS20405
uniprot id: A0A223SDY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1235441:CDO52 RS13870
gene id: 1235441:CDO52_RS13870
uniprot id: A0A223S6H8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1235441:CDO52 RS25225
gene id: 1235441:CDO52_RS25225
uniprot id: A0A223SC35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1235441:CDO52 RS08855
gene id: 1235441:CDO52_RS08855
uniprot id: A0A223S433
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1235441:CDO52 RS09780
gene id: 1235441:CDO52_RS09780
uniprot id: A0A223S4I1
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25535
gene id: 1235441:CDO52_RS25535
uniprot id: A0A223SCA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1235441:CDO52 RS06340
gene id: 1235441:CDO52_RS06340
uniprot id: A0A223S2U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1235441:CDO52 RS01715
gene id: 1235441:CDO52_RS01715
uniprot id: A0A223S0M9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS06840
gene id: 1235441:CDO52_RS06840
uniprot id: A0A223S335
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1235441:CDO52 RS12350
gene id: 1235441:CDO52_RS12350
uniprot id: A0A223S5S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1235441:CDO52 RS12680
gene id: 1235441:CDO52_RS12680
uniprot id: A0A223SDF2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1235441:CDO52 RS20890
gene id: 1235441:CDO52_RS20890
uniprot id: A0A223SA02
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1235441:CDO52 RS21900
gene id: 1235441:CDO52_RS21900
uniprot id: A0A223SAC7
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS17715
gene id: 1235441:CDO52_RS17715
uniprot id: A0A223S8E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1235441:CDO52 RS09925
gene id: 1235441:CDO52_RS09925
uniprot id: A0A223S4I2
names: Similarity
messages: Belongs to the malate synthase family.

1235441:CDO52 RS11915
gene id: 1235441:CDO52_RS11915
uniprot id: A0A223S5J9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1235441:CDO52 RS24620
gene id: 1235441:CDO52_RS24620
uniprot id: A0A223SC04
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS16190
gene id: 1235441:CDO52_RS16190
uniprot id: A0A223S7L6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1235441:CDO52 RS03730
gene id: 1235441:CDO52_RS03730
uniprot id: A0A223S1J7
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS04475
gene id: 1235441:CDO52_RS04475
uniprot id: A0A223S1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1235441:CDO52 RS18770
gene id: 1235441:CDO52_RS18770
uniprot id: A0A223SDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1235441:CDO52 RS16420
gene id: 1235441:CDO52_RS16420
uniprot id: A0A223S7T8
names: Subcellular Location Annotation
messages: Cytoplasm

1235441:CDO52 RS11805
gene id: 1235441:CDO52_RS11805
uniprot id: A0A223S5F0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS16475
gene id: 1235441:CDO52_RS16475
uniprot id: A0A223S7S4
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS09120
gene id: 1235441:CDO52_RS09120
uniprot id: A0A223S462
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1235441:CDO52 RS14700
gene id: 1235441:CDO52_RS14700
uniprot id: A0A223SDS1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS25545
gene id: 1235441:CDO52_RS25545
uniprot id: A0A223SC31
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1235441:CDO52 RS10865
gene id: 1235441:CDO52_RS10865
uniprot id: A0A223S4X9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1235441:CDO52 RS09345
gene id: 1235441:CDO52_RS09345
uniprot id: A0A223S4B1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1235441:CDO52 RS08680
gene id: 1235441:CDO52_RS08680
uniprot id: A0A223S3Y2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1235441:CDO52 RS25185
gene id: 1235441:CDO52_RS25185
uniprot id: A0A223SBW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1235441:CDO52 RS26440
gene id: 1235441:CDO52_RS26440
uniprot id: A0A223SCQ6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1235441:CDO52 RS25270
gene id: 1235441:CDO52_RS25270
uniprot id: A0A223SBX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1235441:CDO52 RS01570
gene id: 1235441:CDO52_RS01570
uniprot id: A0A223S0N8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS07475
gene id: 1235441:CDO52_RS07475
uniprot id: A0A223S3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1235441:CDO52 RS23050
gene id: 1235441:CDO52_RS23050
uniprot id: A0A223SAT4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1235441:CDO52 RS19165
gene id: 1235441:CDO52_RS19165
uniprot id: A0A223S930
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1235441:CDO52 RS11735
gene id: 1235441:CDO52_RS11735
uniprot id: A0A223S5E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1235441:CDO52 RS06565
gene id: 1235441:CDO52_RS06565
uniprot id: A0A223S394
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1235441:CDO52 RS14190
gene id: 1235441:CDO52_RS14190
uniprot id: A0A223S6M8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1235441:CDO52 RS20310
gene id: 1235441:CDO52_RS20310
uniprot id: A0A223S9U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1235441:CDO52 RS04595
gene id: 1235441:CDO52_RS04595
uniprot id: A0A223S205
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1235441:CDO52 RS00565
gene id: 1235441:CDO52_RS00565
uniprot id: A0A223S021
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1235441:CDO52 RS19425
gene id: 1235441:CDO52_RS19425
uniprot id: A0A223S978
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1235441:CDO52 RS25560
gene id: 1235441:CDO52_RS25560
uniprot id: A0A223SC28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1235441:CDO52 RS26450
gene id: 1235441:CDO52_RS26450
uniprot id: A0A223SCJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1235441:CDO52 RS22265
gene id: 1235441:CDO52_RS22265
uniprot id: A0A223SAJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS26300
gene id: 1235441:CDO52_RS26300
uniprot id: A0A223SCK9
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS09505
gene id: 1235441:CDO52_RS09505
uniprot id: A0A223SDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1235441:CDO52 RS06885
gene id: 1235441:CDO52_RS06885
uniprot id: A0A223S342
names: Similarity
messages: Belongs to the peptidase C40 family.

1235441:CDO52 RS18055
gene id: 1235441:CDO52_RS18055
uniprot id: A0A223S8K2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1235441:CDO52 RS10590
gene id: 1235441:CDO52_RS10590
uniprot id: A0A223S4T8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS25510
gene id: 1235441:CDO52_RS25510
uniprot id: A0A223SC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1235441:CDO52 RS10215
gene id: 1235441:CDO52_RS10215
uniprot id: A0A223S4P7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1235441:CDO52 RS24690
gene id: 1235441:CDO52_RS24690
uniprot id: A0A223SBU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1235441:CDO52 RS14605
gene id: 1235441:CDO52_RS14605
uniprot id: A0A223S6T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1235441:CDO52 RS24050
gene id: 1235441:CDO52_RS24050
uniprot id: A0A223SBR1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS08385
gene id: 1235441:CDO52_RS08385
uniprot id: A0A223S3T6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1235441:CDO52 RS00380
gene id: 1235441:CDO52_RS00380
uniprot id: A0A223S017
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS21060
gene id: 1235441:CDO52_RS21060
uniprot id: A0A223S9Z0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS08110
gene id: 1235441:CDO52_RS08110
uniprot id: A0A223S400
names: Subunit
messages: Homodimer.

1235441:CDO52 RS23595
gene id: 1235441:CDO52_RS23595
uniprot id: A0A223SB94
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS16815
gene id: 1235441:CDO52_RS16815
uniprot id: A0A223S7Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1235441:CDO52 RS14250
gene id: 1235441:CDO52_RS14250
uniprot id: A0A223S6M7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS24405
gene id: 1235441:CDO52_RS24405
uniprot id: A0A223SBW8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1235441:CDO52 RS08170
gene id: 1235441:CDO52_RS08170
uniprot id: A0A223S3Q7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1235441:CDO52 RS04415
gene id: 1235441:CDO52_RS04415
uniprot id: A0A223S1X9
names: Similarity
messages: Belongs to the YciI family.

1235441:CDO52 RS19840
gene id: 1235441:CDO52_RS19840
uniprot id: A0A223S9G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS25170
gene id: 1235441:CDO52_RS25170
uniprot id: A0A223SBV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1235441:CDO52 RS21955
gene id: 1235441:CDO52_RS21955
uniprot id: A0A223SAD6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS12100
gene id: 1235441:CDO52_RS12100
uniprot id: A0A223S5N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1235441:CDO52 RS12160
gene id: 1235441:CDO52_RS12160
uniprot id: A0A223S5M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1235441:CDO52 RS20755
gene id: 1235441:CDO52_RS20755
uniprot id: A0A223SA17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1235441:CDO52 RS20730
gene id: 1235441:CDO52_RS20730
uniprot id: A0A223S9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1235441:CDO52 RS14075
gene id: 1235441:CDO52_RS14075
uniprot id: A0A223S6K1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1235441:CDO52 RS24250
gene id: 1235441:CDO52_RS24250
uniprot id: A0A223SBR5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1235441:CDO52 RS04670
gene id: 1235441:CDO52_RS04670
uniprot id: A0A223S200
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1235441:CDO52 RS20300
gene id: 1235441:CDO52_RS20300
uniprot id: A0A223S9L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1235441:CDO52 RS09410
gene id: 1235441:CDO52_RS09410
uniprot id: A0A223S4C2
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

1235441:CDO52 RS07610
gene id: 1235441:CDO52_RS07610
uniprot id: A0A223S3H1
names: Similarity
messages: Belongs to the peptidase S1 family.

1235441:CDO52 RS08330
gene id: 1235441:CDO52_RS08330
uniprot id: A0A223S3S5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1235441:CDO52 RS03555
gene id: 1235441:CDO52_RS03555
uniprot id: A0A223S1J0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1235441:CDO52 RS25140
gene id: 1235441:CDO52_RS25140
uniprot id: A0A223SC29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1235441:CDO52 RS10910
gene id: 1235441:CDO52_RS10910
uniprot id: A0A223SDL2
names: Similarity
messages: Belongs to the CsoR family.

1235441:CDO52 RS26585
gene id: 1235441:CDO52_RS26585
uniprot id: A0A223SCQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS11835
gene id: 1235441:CDO52_RS11835
uniprot id: A0A223S5G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1235441:CDO52 RS12095
gene id: 1235441:CDO52_RS12095
uniprot id: A0A223S5K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS04600
gene id: 1235441:CDO52_RS04600
uniprot id: A0A223S262
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1235441:CDO52 RS11905
gene id: 1235441:CDO52_RS11905
uniprot id: A0A223S5T7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS02555
gene id: 1235441:CDO52_RS02555
uniprot id: A0A223S0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Secreted

1235441:CDO52 RS18075
gene id: 1235441:CDO52_RS18075
uniprot id: A0A223S8L0
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1235441:CDO52 RS06910
gene id: 1235441:CDO52_RS06910
uniprot id: A0A223S333
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1235441:CDO52 RS25505
gene id: 1235441:CDO52_RS25505
uniprot id: A0A223SE73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1235441:CDO52 RS20305
gene id: 1235441:CDO52_RS20305
uniprot id: A0A223S9L4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1235441:CDO52 RS01905
gene id: 1235441:CDO52_RS01905
uniprot id: A0A223S0P8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1235441:CDO52 RS24725
gene id: 1235441:CDO52_RS24725
uniprot id: A0A223SBW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1235441:CDO52 RS16905
gene id: 1235441:CDO52_RS16905
uniprot id: A0A223S812
names: Similarity
messages: Belongs to the catalase family.

1235441:CDO52 RS02800
gene id: 1235441:CDO52_RS02800
uniprot id: A0A223S150
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1235441:CDO52 RS02150
gene id: 1235441:CDO52_RS02150
uniprot id: A0A223S147
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1235441:CDO52 RS08890
gene id: 1235441:CDO52_RS08890
uniprot id: A0A223S426
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1235441:CDO52 RS13615
gene id: 1235441:CDO52_RS13615
uniprot id: A0A223S6D6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1235441:CDO52 RS11290
gene id: 1235441:CDO52_RS11290
uniprot id: A0A223S592
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1235441:CDO52 RS05635
gene id: 1235441:CDO52_RS05635
uniprot id: A0A223S2I3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1235441:CDO52 RS23215
gene id: 1235441:CDO52_RS23215
uniprot id: A0A223SB38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS11115
gene id: 1235441:CDO52_RS11115
uniprot id: A0A223S562
names: Similarity
messages: Belongs to the CdaR family.

1235441:CDO52 RS16110
gene id: 1235441:CDO52_RS16110
uniprot id: A0A223S7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1235441:CDO52 RS09490
gene id: 1235441:CDO52_RS09490
uniprot id: A0A223S4N0
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1235441:CDO52 RS05445
gene id: 1235441:CDO52_RS05445
uniprot id: A0A223S2D5
names: Similarity
messages: Belongs to the TPP enzyme family.

1235441:CDO52 RS17370
gene id: 1235441:CDO52_RS17370
uniprot id: A0A223S8B3
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS11485
gene id: 1235441:CDO52_RS11485
uniprot id: A0A223S5B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1235441:CDO52 RS10365
gene id: 1235441:CDO52_RS10365
uniprot id: A0A223S4R8
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

1235441:CDO52 RS08950
gene id: 1235441:CDO52_RS08950
uniprot id: A0A223S439
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1235441:CDO52 RS25200
gene id: 1235441:CDO52_RS25200
uniprot id: A0A223SBX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1235441:CDO52 RS18200
gene id: 1235441:CDO52_RS18200
uniprot id: A0A223S8M9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1235441:CDO52 RS25485
gene id: 1235441:CDO52_RS25485
uniprot id: A0A223SC21
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1235441:CDO52 RS21985
gene id: 1235441:CDO52_RS21985
uniprot id: A0A223SAG0
names: Similarity
messages: Belongs to the thioesterase family.

1235441:CDO52 RS23190
gene id: 1235441:CDO52_RS23190
uniprot id: A0A223SAX7
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS03490
gene id: 1235441:CDO52_RS03490
uniprot id: A0A223S1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1235441:CDO52 RS11355
gene id: 1235441:CDO52_RS11355
uniprot id: A0A223S579
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1235441:CDO52 RS08895
gene id: 1235441:CDO52_RS08895
uniprot id: A0A223S434
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1235441:CDO52 RS01575
gene id: 1235441:CDO52_RS01575
uniprot id: A0A223S0M5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1235441:CDO52 RS00555
gene id: 1235441:CDO52_RS00555
uniprot id: A0A223S0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS09700
gene id: 1235441:CDO52_RS09700
uniprot id: A0A223S4K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1235441:CDO52 RS23345
gene id: 1235441:CDO52_RS23345
uniprot id: A0A223SB76
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS19050
gene id: 1235441:CDO52_RS19050
uniprot id: A0A223S929
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1235441:CDO52 RS20165
gene id: 1235441:CDO52_RS20165
uniprot id: A0A223S9M0
names: Similarity
messages: Belongs to the hyi family.

1235441:CDO52 RS17930
gene id: 1235441:CDO52_RS17930
uniprot id: A0A223S8H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1235441:CDO52 RS10055
gene id: 1235441:CDO52_RS10055
uniprot id: A0A223S4J8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1235441:CDO52 RS10820
gene id: 1235441:CDO52_RS10820
uniprot id: A0A223S4Y1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1235441:CDO52 RS26270
gene id: 1235441:CDO52_RS26270
uniprot id: A0A223SCM4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1235441:CDO52 RS13310
gene id: 1235441:CDO52_RS13310
uniprot id: A0A223S685
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1235441:CDO52 RS05395
gene id: 1235441:CDO52_RS05395
uniprot id: A0A223S2C8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1235441:CDO52 RS06750
gene id: 1235441:CDO52_RS06750
uniprot id: A0A223S3C9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1235441:CDO52 RS05255
gene id: 1235441:CDO52_RS05255
uniprot id: A0A223S2B9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1235441:CDO52 RS04530
gene id: 1235441:CDO52_RS04530
uniprot id: A0A223S1Z1
names: Similarity
messages: Belongs to the PstS family.

1235441:CDO52 RS02905
gene id: 1235441:CDO52_RS02905
uniprot id: A0A223S186
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1235441:CDO52 RS24360
gene id: 1235441:CDO52_RS24360
uniprot id: A0A223SBN7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1235441:CDO52 RS05705
gene id: 1235441:CDO52_RS05705
uniprot id: A0A223S2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS15560
gene id: 1235441:CDO52_RS15560
uniprot id: A0A223S7G1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1235441:CDO52 RS08645
gene id: 1235441:CDO52_RS08645
uniprot id: A0A223S3Z4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1235441:CDO52 RS19650
gene id: 1235441:CDO52_RS19650
uniprot id: A0A223S9C4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1235441:CDO52 RS20495
gene id: 1235441:CDO52_RS20495
uniprot id: A0A223S9N9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1235441:CDO52 RS11420
gene id: 1235441:CDO52_RS11420
uniprot id: A0A223S5B2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS25340
gene id: 1235441:CDO52_RS25340
uniprot id: A0A223SC91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1235441:CDO52 RS10010
gene id: 1235441:CDO52_RS10010
uniprot id: A0A223S4N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1235441:CDO52 RS05300
gene id: 1235441:CDO52_RS05300
uniprot id: A0A223S2N0
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS20525
gene id: 1235441:CDO52_RS20525
uniprot id: A0A223S9U8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1235441:CDO52 RS23690
gene id: 1235441:CDO52_RS23690
uniprot id: A0A223SBD7
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25285
gene id: 1235441:CDO52_RS25285
uniprot id: A0A223SBY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1235441:CDO52 RS07215
gene id: 1235441:CDO52_RS07215
uniprot id: A0A223S391
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1235441:CDO52 RS06325
gene id: 1235441:CDO52_RS06325
uniprot id: A0A223S2U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1235441:CDO52 RS04100
gene id: 1235441:CDO52_RS04100
uniprot id: A0A223S225
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1235441:CDO52 RS18610
gene id: 1235441:CDO52_RS18610
uniprot id: A0A223S8Y6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1235441:CDO52 RS04245
gene id: 1235441:CDO52_RS04245
uniprot id: A0A223S1U1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1235441:CDO52 RS25665
gene id: 1235441:CDO52_RS25665
uniprot id: A0A223SCJ3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1235441:CDO52 RS26575
gene id: 1235441:CDO52_RS26575
uniprot id: A0A223SCL4
names: Similarity
messages: Belongs to the citrate synthase family.

1235441:CDO52 RS25635
gene id: 1235441:CDO52_RS25635
uniprot id: A0A223SC50
names: Similarity
messages: Belongs to the histone deacetylase family.

1235441:CDO52 RS23205
gene id: 1235441:CDO52_RS23205
uniprot id: A0A223SB34
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1235441:CDO52 RS22960
gene id: 1235441:CDO52_RS22960
uniprot id: A0A223SAS1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1235441:CDO52 RS25245
gene id: 1235441:CDO52_RS25245
uniprot id: A0A223SC58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1235441:CDO52 RS11050
gene id: 1235441:CDO52_RS11050
uniprot id: A0A223S551
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS08000
gene id: 1235441:CDO52_RS08000
uniprot id: A0A223S3Y0
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS10185
gene id: 1235441:CDO52_RS10185
uniprot id: A0A223S4U5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS23460
gene id: 1235441:CDO52_RS23460
uniprot id: A0A223SB28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1235441:CDO52 RS12450
gene id: 1235441:CDO52_RS12450
uniprot id: A0A223S5T9
names: Similarity
messages: Belongs to the TrpC family.

1235441:CDO52 RS25095
gene id: 1235441:CDO52_RS25095
uniprot id: A0A223SBV4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1235441:CDO52 RS04675
gene id: 1235441:CDO52_RS04675
uniprot id: A0A223S222
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1235441:CDO52 RS14245
gene id: 1235441:CDO52_RS14245
uniprot id: A0A223S6P0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1235441:CDO52 RS23210
gene id: 1235441:CDO52_RS23210
uniprot id: A0A223SAW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1235441:CDO52 RS22990
gene id: 1235441:CDO52_RS22990
uniprot id: A0A223SB78
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1235441:CDO52 RS03560
gene id: 1235441:CDO52_RS03560
uniprot id: A0A223S1R6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1235441:CDO52 RS10925
gene id: 1235441:CDO52_RS10925
uniprot id: A0A223S4Y7
names: Similarity
messages: Belongs to the peptidase S15 family.

1235441:CDO52 RS16655
gene id: 1235441:CDO52_RS16655
uniprot id: A0A223S7V0
names: Similarity
messages: Belongs to the Fmt family.

1235441:CDO52 RS24440
gene id: 1235441:CDO52_RS24440
uniprot id: A0A223SBR8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1235441:CDO52 RS06675
gene id: 1235441:CDO52_RS06675
uniprot id: A0A223S300
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1235441:CDO52 RS24750
gene id: 1235441:CDO52_RS24750
uniprot id: A0A223SBW0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1235441:CDO52 RS19270
gene id: 1235441:CDO52_RS19270
uniprot id: A0A223S954
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1235441:CDO52 RS20840
gene id: 1235441:CDO52_RS20840
uniprot id: A0A223S9W5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1235441:CDO52 RS26490
gene id: 1235441:CDO52_RS26490
uniprot id: A0A223SCR0
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS09960
gene id: 1235441:CDO52_RS09960
uniprot id: A0A223S4N5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1235441:CDO52 RS23045
gene id: 1235441:CDO52_RS23045
uniprot id: A0A223SB04
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1235441:CDO52 RS13190
gene id: 1235441:CDO52_RS13190
uniprot id: A0A223S693
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1235441:CDO52 RS05315
gene id: 1235441:CDO52_RS05315
uniprot id: A0A223S2C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1235441:CDO52 RS20220
gene id: 1235441:CDO52_RS20220
uniprot id: A0A223S9K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1235441:CDO52 RS23220
gene id: 1235441:CDO52_RS23220
uniprot id: A0A223SB73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1235441:CDO52 RS21855
gene id: 1235441:CDO52_RS21855
uniprot id: A0A223SAC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS19310
gene id: 1235441:CDO52_RS19310
uniprot id: A0A223S974
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1235441:CDO52 RS05055
gene id: 1235441:CDO52_RS05055
uniprot id: A0A223S284
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1235441:CDO52 RS18860
gene id: 1235441:CDO52_RS18860
uniprot id: A0A223S8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1235441:CDO52 RS04690
gene id: 1235441:CDO52_RS04690
uniprot id: A0A223S227
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1235441:CDO52 RS25325
gene id: 1235441:CDO52_RS25325
uniprot id: A0A223SE68
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS01510
gene id: 1235441:CDO52_RS01510
uniprot id: A0A223S0K3
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS19690
gene id: 1235441:CDO52_RS19690
uniprot id: A0A223S9C2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1235441:CDO52 RS18920
gene id: 1235441:CDO52_RS18920
uniprot id: A0A223S8Z2
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS12130
gene id: 1235441:CDO52_RS12130
uniprot id: A0A223S5Q8
names: Similarity
messages: Belongs to the YggT family.

1235441:CDO52 RS18375
gene id: 1235441:CDO52_RS18375
uniprot id: A0A223S8Q5
names: Similarity
messages: Belongs to the UPF0098 family.

1235441:CDO52 RS17160
gene id: 1235441:CDO52_RS17160
uniprot id: A0A223S840
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS25250
gene id: 1235441:CDO52_RS25250
uniprot id: A0A223SBY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1235441:CDO52 RS22790
gene id: 1235441:CDO52_RS22790
uniprot id: A0A223SAQ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1235441:CDO52 RS05035
gene id: 1235441:CDO52_RS05035
uniprot id: A0A223S280
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1235441:CDO52 RS17045
gene id: 1235441:CDO52_RS17045
uniprot id: A0A223S820
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS26675
gene id: 1235441:CDO52_RS26675
uniprot id: A0A223SCL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS05510
gene id: 1235441:CDO52_RS05510
uniprot id: A0A223S2F9
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1235441:CDO52 RS04190
gene id: 1235441:CDO52_RS04190
uniprot id: A0A223S1U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1235441:CDO52 RS17080
gene id: 1235441:CDO52_RS17080
uniprot id: A0A223S841
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1235441:CDO52 RS03410
gene id: 1235441:CDO52_RS03410
uniprot id: A0A223S1E3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS13735
gene id: 1235441:CDO52_RS13735
uniprot id: A0A223S6D5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1235441:CDO52 RS04950
gene id: 1235441:CDO52_RS04950
uniprot id: A0A223S2C0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1235441:CDO52 RS19265
gene id: 1235441:CDO52_RS19265
uniprot id: A0A223SDX4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1235441:CDO52 RS09390
gene id: 1235441:CDO52_RS09390
uniprot id: A0A223S4F0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1235441:CDO52 RS16890
gene id: 1235441:CDO52_RS16890
uniprot id: A0A223S7Y9
names: Similarity
messages: Belongs to the universal stress protein A family.

1235441:CDO52 RS15330
gene id: 1235441:CDO52_RS15330
uniprot id: A0A223S784
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1235441:CDO52 RS24945
gene id: 1235441:CDO52_RS24945
uniprot id: A0A223SBQ5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1235441:CDO52 RS09405
gene id: 1235441:CDO52_RS09405
uniprot id: A0A223S4B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1235441:CDO52 RS07910
gene id: 1235441:CDO52_RS07910
uniprot id: A0A223S3K4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1235441:CDO52 RS06415
gene id: 1235441:CDO52_RS06415
uniprot id: A0A223S2V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1235441:CDO52 RS19145
gene id: 1235441:CDO52_RS19145
uniprot id: A0A223S945
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1235441:CDO52 RS21210
gene id: 1235441:CDO52_RS21210
uniprot id: A0A223SA45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS07465
gene id: 1235441:CDO52_RS07465
uniprot id: A0A223S3E5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1235441:CDO52 RS26275
gene id: 1235441:CDO52_RS26275
uniprot id: A0A223SCF8
names: Similarity
messages: Belongs to the peptidase S33 family.

1235441:CDO52 RS03215
gene id: 1235441:CDO52_RS03215
uniprot id: A0A223S1F0
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1235441:CDO52 RS18785
gene id: 1235441:CDO52_RS18785
uniprot id: A0A223S924
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS09850
gene id: 1235441:CDO52_RS09850
uniprot id: A0A223S4I9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1235441:CDO52 RS21875
gene id: 1235441:CDO52_RS21875
uniprot id: A0A223SE63
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1235441:CDO52 RS01970
gene id: 1235441:CDO52_RS01970
uniprot id: A0A223S0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1235441:CDO52 RS20415
gene id: 1235441:CDO52_RS20415
uniprot id: A0A223S9S4
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1235441:CDO52 RS02050
gene id: 1235441:CDO52_RS02050
uniprot id: A0A223S0S4
names: Similarity
messages: Belongs to the thioredoxin family.

1235441:CDO52 RS12595
gene id: 1235441:CDO52_RS12595
uniprot id: A0A223S663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1235441:CDO52 RS17240
gene id: 1235441:CDO52_RS17240
uniprot id: A0A223S857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1235441:CDO52 RS24415
gene id: 1235441:CDO52_RS24415
uniprot id: A0A223SBG9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1235441:CDO52 RS25600
gene id: 1235441:CDO52_RS25600
uniprot id: A0A223SC43
names: Subcellular Location Annotation
messages: Membrane

1235441:CDO52 RS25125
gene id: 1235441:CDO52_RS25125
uniprot id: A0A223SC13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1235441:CDO52 RS19715
gene id: 1235441:CDO52_RS19715
uniprot id: A0A223S9E4
names: Similarity
messages: Belongs to the UPF0276 family.

1235441:CDO52 RS23930
gene id: 1235441:CDO52_RS23930
uniprot id: A0A223SBG3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1235441:CDO52 RS26360
gene id: 1235441:CDO52_RS26360
uniprot id: A0A223SCL8
names: Similarity
messages: Belongs to the peptidase M7 family.

1235441:CDO52 RS04525
gene id: 1235441:CDO52_RS04525
uniprot id: A0A223S1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1235441:CDO52 RS08665
gene id: 1235441:CDO52_RS08665
uniprot id: A0A223S403
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1235441:CDO52 RS13730
gene id: 1235441:CDO52_RS13730
uniprot id: A0A223S6I3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1235441:CDO52 RS10410
gene id: 1235441:CDO52_RS10410
uniprot id: A0A223S4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1235441:CDO52 RS04785
gene id: 1235441:CDO52_RS04785
uniprot id: A0A223S2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1235441:CDO52 RS19280
gene id: 1235441:CDO52_RS19280
uniprot id: A0A223S951
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1235441:CDO52 RS24975
gene id: 1235441:CDO52_RS24975
uniprot id: A0A223SC03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1235441:CDO52 RS19195
gene id: 1235441:CDO52_RS19195
uniprot id: A0A223SDS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1235441:CDO52 RS06135
gene id: 1235441:CDO52_RS06135
uniprot id: A0A223S2S1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1235441:CDO52 RS23945
gene id: 1235441:CDO52_RS23945
uniprot id: A0A223SBL5
names: Similarity
messages: Belongs to the stealth family.

1235441:CDO52 RS21905
gene id: 1235441:CDO52_RS21905
uniprot id: A0A223SAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1235441:CDO52 RS10325
gene id: 1235441:CDO52_RS10325
uniprot id: A0A223S4R3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1235441:CDO52 RS19585
gene id: 1235441:CDO52_RS19585
uniprot id: A0A223S9B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS19215
gene id: 1235441:CDO52_RS19215
uniprot id: A0A223S944
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1235441:CDO52 RS12355
gene id: 1235441:CDO52_RS12355
uniprot id: A0A223S5S1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1235441:CDO52 RS01500
gene id: 1235441:CDO52_RS01500
uniprot id: A0A223S0K9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1235441:CDO52 RS20945
gene id: 1235441:CDO52_RS20945
uniprot id: A0A223S9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1235441:CDO52 RS01065
gene id: 1235441:CDO52_RS01065
uniprot id: A0A223S0D3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1235441:CDO52 RS09010
gene id: 1235441:CDO52_RS09010
uniprot id: A0A223S446
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1235441:CDO52 RS09975
gene id: 1235441:CDO52_RS09975
uniprot id: A0A223S4L3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1235441:CDO52 RS14885
gene id: 1235441:CDO52_RS14885
uniprot id: A0A223S712
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1235441:CDO52 RS25735
gene id: 1235441:CDO52_RS25735
uniprot id: A0A223SEB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Belongs to the NadC/ModD family.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm
messages: Involved in the catabolism of quinolinic acid (QA).

1235441:CDO52 RS16290
gene id: 1235441:CDO52_RS16290
uniprot id: A0A223SDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1235441:CDO52 RS14890
gene id: 1235441:CDO52_RS14890
uniprot id: A0A223S6Z5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1235441:CDO52 RS23235
gene id: 1235441:CDO52_RS23235
uniprot id: A0A223SB55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.