1226968:A6A40 RS01840
gene id: 1226968:A6A40_RS01840
uniprot id: A0A160JDF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1226968:A6A40 RS08870
gene id: 1226968:A6A40_RS08870
uniprot id: A0A160JJ16
names: Similarity
messages: Belongs to the peptidase C56 family.

1226968:A6A40 RS06870
gene id: 1226968:A6A40_RS06870
uniprot id: A0A160JFG6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1226968:A6A40 RS09385
gene id: 1226968:A6A40_RS09385
uniprot id: A0A160JGI9
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS25225
gene id: 1226968:A6A40_RS25225
uniprot id: A0A2R4VVE2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1226968:A6A40 RS13895
gene id: 1226968:A6A40_RS13895
uniprot id: A0A160JID1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS02055
gene id: 1226968:A6A40_RS02055
uniprot id: A0A160JDJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS14305
gene id: 1226968:A6A40_RS14305
uniprot id: A0A160JIG2
names: Similarity
messages: Belongs to the aldose epimerase family.

1226968:A6A40 RS00880
gene id: 1226968:A6A40_RS00880
uniprot id: A0A160JD29
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1226968:A6A40 RS04965
gene id: 1226968:A6A40_RS04965
uniprot id: A0A160JFG3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS00715
gene id: 1226968:A6A40_RS00715
uniprot id: A0A161JGR1
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1226968:A6A40 RS06670
gene id: 1226968:A6A40_RS06670
uniprot id: A0A160JFE5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1226968:A6A40 RS07185
gene id: 1226968:A6A40_RS07185
uniprot id: A0A160JJG4
names: Similarity
messages: Belongs to the CFA/CMAS family.

1226968:A6A40 RS01560
gene id: 1226968:A6A40_RS01560
uniprot id: A0A160JDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1226968:A6A40 RS09605
gene id: 1226968:A6A40_RS09605
uniprot id: A0A160JGM3
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1226968:A6A40 RS11935
gene id: 1226968:A6A40_RS11935
uniprot id: A0A160JHM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS11080
gene id: 1226968:A6A40_RS11080
uniprot id: A0A160JH79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1226968:A6A40 RS11670
gene id: 1226968:A6A40_RS11670
uniprot id: A0A160JHF9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS09530
gene id: 1226968:A6A40_RS09530
uniprot id: A0A160JGP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1226968:A6A40 RS07925
gene id: 1226968:A6A40_RS07925
uniprot id: A0A160JFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1226968:A6A40 RS12160
gene id: 1226968:A6A40_RS12160
uniprot id: A0A160JHM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1226968:A6A40 RS00550
gene id: 1226968:A6A40_RS00550
uniprot id: A0A168XZ55
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS08740
gene id: 1226968:A6A40_RS08740
uniprot id: A0A160JIZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1226968:A6A40 RS11280
gene id: 1226968:A6A40_RS11280
uniprot id: A0A160JHA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS07815
gene id: 1226968:A6A40_RS07815
uniprot id: A0A168Y670
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1226968:A6A40 RS01555
gene id: 1226968:A6A40_RS01555
uniprot id: A0A161IPP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1226968:A6A40 RS09535
gene id: 1226968:A6A40_RS09535
uniprot id: A0A168Y7S7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1226968:A6A40 RS12370
gene id: 1226968:A6A40_RS12370
uniprot id: A0A160JHU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1226968:A6A40 RS03765
gene id: 1226968:A6A40_RS03765
uniprot id: A0A160JE70
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1226968:A6A40 RS11290
gene id: 1226968:A6A40_RS11290
uniprot id: A0A168Y9D7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1226968:A6A40 RS06985
gene id: 1226968:A6A40_RS06985
uniprot id: A0A160JFI2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1226968:A6A40 RS14310
gene id: 1226968:A6A40_RS14310
uniprot id: A0A160JII0
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS09185
gene id: 1226968:A6A40_RS09185
uniprot id: A0A161IU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1226968:A6A40 RS00355
gene id: 1226968:A6A40_RS00355
uniprot id: A0A160JD03
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1226968:A6A40 RS00660
gene id: 1226968:A6A40_RS00660
uniprot id: A0A168YCP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

1226968:A6A40 RS04940
gene id: 1226968:A6A40_RS04940
uniprot id: A0A160JER2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS02085
gene id: 1226968:A6A40_RS02085
uniprot id: A0A160JDP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1226968:A6A40 RS03315
gene id: 1226968:A6A40_RS03315
uniprot id: A0A160JE71
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1226968:A6A40 RS07155
gene id: 1226968:A6A40_RS07155
uniprot id: A0A161JH56
names: Similarity
messages: Belongs to the fabD family.

1226968:A6A40 RS12470
gene id: 1226968:A6A40_RS12470
uniprot id: A0A160JHS5
names: Similarity
messages: Belongs to the PhoH family.

1226968:A6A40 RS01685
gene id: 1226968:A6A40_RS01685
uniprot id: A0A160JE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS05680
gene id: 1226968:A6A40_RS05680
uniprot id: A0A160JF02
names: Function
messages: Multidrug efflux pump.

1226968:A6A40 RS02270
gene id: 1226968:A6A40_RS02270
uniprot id: A0A168Y0R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1226968:A6A40 RS08445
gene id: 1226968:A6A40_RS08445
uniprot id: A0A160JG64
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1226968:A6A40 RS03020
gene id: 1226968:A6A40_RS03020
uniprot id: A0A160JDX4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1226968:A6A40 RS32260
gene id: 1226968:A6A40_RS32260
uniprot id: A0A160JFA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS02280
gene id: 1226968:A6A40_RS02280
uniprot id: A0A160JDM5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1226968:A6A40 RS08345
gene id: 1226968:A6A40_RS08345
uniprot id: A0A168Y6M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1226968:A6A40 RS11005
gene id: 1226968:A6A40_RS11005
uniprot id: A0A160JH70
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1226968:A6A40 RS03415
gene id: 1226968:A6A40_RS03415
uniprot id: A0A160JE25
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1226968:A6A40 RS08735
gene id: 1226968:A6A40_RS08735
uniprot id: A0A160JGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1226968:A6A40 RS08565
gene id: 1226968:A6A40_RS08565
uniprot id: A0A160JG93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS03450
gene id: 1226968:A6A40_RS03450
uniprot id: A0A160JE46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1226968:A6A40 RS10680
gene id: 1226968:A6A40_RS10680
uniprot id: A0A160JH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS13150
gene id: 1226968:A6A40_RS13150
uniprot id: A0A160JI31
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS01625
gene id: 1226968:A6A40_RS01625
uniprot id: A0A160JDD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1226968:A6A40 RS11285
gene id: 1226968:A6A40_RS11285
uniprot id: A0A160JHE2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1226968:A6A40 RS05295
gene id: 1226968:A6A40_RS05295
uniprot id: A0A160JEU7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1226968:A6A40 RS11160
gene id: 1226968:A6A40_RS11160
uniprot id: A0A160JHU6
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1226968:A6A40 RS07690
gene id: 1226968:A6A40_RS07690
uniprot id: A0A160JFW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1226968:A6A40 RS07810
gene id: 1226968:A6A40_RS07810
uniprot id: A0A160JG03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1226968:A6A40 RS14135
gene id: 1226968:A6A40_RS14135
uniprot id: A0A160JIY8
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS12360
gene id: 1226968:A6A40_RS12360
uniprot id: A0A160JHQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS06210
gene id: 1226968:A6A40_RS06210
uniprot id: A0A160JF78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1226968:A6A40 RS12355
gene id: 1226968:A6A40_RS12355
uniprot id: A0A161IUB9
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1226968:A6A40 RS06305
gene id: 1226968:A6A40_RS06305
uniprot id: A0A161IPZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1226968:A6A40 RS14300
gene id: 1226968:A6A40_RS14300
uniprot id: A0A161IUM2
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1226968:A6A40 RS11090
gene id: 1226968:A6A40_RS11090
uniprot id: A0A160JH76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1226968:A6A40 RS12685
gene id: 1226968:A6A40_RS12685
uniprot id: A0A160JHU9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1226968:A6A40 RS04590
gene id: 1226968:A6A40_RS04590
uniprot id: A0A168Y3A0
names: Similarity
messages: Belongs to the Skp family.

1226968:A6A40 RS14245
gene id: 1226968:A6A40_RS14245
uniprot id: A0A168YC90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS14470
gene id: 1226968:A6A40_RS14470
uniprot id: A0A160JIL1
names: Similarity
messages: Belongs to the ParB family.

1226968:A6A40 RS00820
gene id: 1226968:A6A40_RS00820
uniprot id: A0A168XZD6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1226968:A6A40 RS00870
gene id: 1226968:A6A40_RS00870
uniprot id: A0A168XZF8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1226968:A6A40 RS06550
gene id: 1226968:A6A40_RS06550
uniprot id: A0A160JFB9
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1226968:A6A40 RS09255
gene id: 1226968:A6A40_RS09255
uniprot id: A0A160JGH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1226968:A6A40 RS14350
gene id: 1226968:A6A40_RS14350
uniprot id: A0A160JJ11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS05910
gene id: 1226968:A6A40_RS05910
uniprot id: A0A168Y4H1
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1226968:A6A40 RS10895
gene id: 1226968:A6A40_RS10895
uniprot id: A0A160JH92
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS09940
gene id: 1226968:A6A40_RS09940
uniprot id: A0A160JHC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1226968:A6A40 RS14620
gene id: 1226968:A6A40_RS14620
uniprot id: A0A168YCJ3
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS10060
gene id: 1226968:A6A40_RS10060
uniprot id: A0A160JGW3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1226968:A6A40 RS09575
gene id: 1226968:A6A40_RS09575
uniprot id: A0A160JH80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1226968:A6A40 RS14180
gene id: 1226968:A6A40_RS14180
uniprot id: A0A160JJ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1226968:A6A40 RS24880
gene id: 1226968:A6A40_RS24880
uniprot id: A0A2R4VV85
names: Similarity
messages: Belongs to the UPF0262 family.

1226968:A6A40 RS08285
gene id: 1226968:A6A40_RS08285
uniprot id: A0A160JG56
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS10395
gene id: 1226968:A6A40_RS10395
uniprot id: A0A160JGY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1226968:A6A40 RS09900
gene id: 1226968:A6A40_RS09900
uniprot id: A0A168Y846
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS14600
gene id: 1226968:A6A40_RS14600
uniprot id: A0A160JIM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1226968:A6A40 RS10520
gene id: 1226968:A6A40_RS10520
uniprot id: A0A160JGZ7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1226968:A6A40 RS05420
gene id: 1226968:A6A40_RS05420
uniprot id: A0A160JEW3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1226968:A6A40 RS01015
gene id: 1226968:A6A40_RS01015
uniprot id: A0A160JD46
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1226968:A6A40 RS10815
gene id: 1226968:A6A40_RS10815
uniprot id: A0A160JHP9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1226968:A6A40 RS09770
gene id: 1226968:A6A40_RS09770
uniprot id: A0A160JGN3
names: Similarity
messages: Belongs to the MT-A70-like family.

1226968:A6A40 RS32280
gene id: 1226968:A6A40_RS32280
uniprot id: A0A160JIJ9
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

1226968:A6A40 RS04190
gene id: 1226968:A6A40_RS04190
uniprot id: A0A160JEF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1226968:A6A40 RS02385
gene id: 1226968:A6A40_RS02385
uniprot id: A0A161IPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1226968:A6A40 RS12935
gene id: 1226968:A6A40_RS12935
uniprot id: A0A160JI22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1226968:A6A40 RS07490
gene id: 1226968:A6A40_RS07490
uniprot id: A0A160JFV3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1226968:A6A40 RS06720
gene id: 1226968:A6A40_RS06720
uniprot id: A0A160JFE4
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1226968:A6A40 RS03630
gene id: 1226968:A6A40_RS03630
uniprot id: A0A168Y270
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1226968:A6A40 RS01885
gene id: 1226968:A6A40_RS01885
uniprot id: A0A160JDF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1226968:A6A40 RS07725
gene id: 1226968:A6A40_RS07725
uniprot id: A0A160JFX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1226968:A6A40 RS04700
gene id: 1226968:A6A40_RS04700
uniprot id: A0A160JEL8
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

1226968:A6A40 RS07935
gene id: 1226968:A6A40_RS07935
uniprot id: A0A168Y6C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1226968:A6A40 RS04830
gene id: 1226968:A6A40_RS04830
uniprot id: A0A160JEQ0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1226968:A6A40 RS12010
gene id: 1226968:A6A40_RS12010
uniprot id: A0A160JHK0
names: Similarity
messages: Belongs to the ros/MucR family.

1226968:A6A40 RS09805
gene id: 1226968:A6A40_RS09805
uniprot id: A0A160JGQ3
names: Similarity
messages: Belongs to the RNase T2 family.

1226968:A6A40 RS10420
gene id: 1226968:A6A40_RS10420
uniprot id: A0A160JGY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1226968:A6A40 RS06340
gene id: 1226968:A6A40_RS06340
uniprot id: A0A160JIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1226968:A6A40 RS08100
gene id: 1226968:A6A40_RS08100
uniprot id: A0A168Y6F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS08270
gene id: 1226968:A6A40_RS08270
uniprot id: A0A161JH78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1226968:A6A40 RS01460
gene id: 1226968:A6A40_RS01460
uniprot id: A0A160JDA2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1226968:A6A40 RS01820
gene id: 1226968:A6A40_RS01820
uniprot id: A0A160JDF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1226968:A6A40 RS09845
gene id: 1226968:A6A40_RS09845
uniprot id: A0A168Y816
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS12220
gene id: 1226968:A6A40_RS12220
uniprot id: A0A160JI83
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1226968:A6A40 RS03655
gene id: 1226968:A6A40_RS03655
uniprot id: A0A160JEB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1226968:A6A40 RS01435
gene id: 1226968:A6A40_RS01435
uniprot id: A0A160JDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

1226968:A6A40 RS25330
gene id: 1226968:A6A40_RS25330
uniprot id: A0A2R4VVG3
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1226968:A6A40 RS06125
gene id: 1226968:A6A40_RS06125
uniprot id: A0A160JF76
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1226968:A6A40 RS06365
gene id: 1226968:A6A40_RS06365
uniprot id: A0A160JFA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1226968:A6A40 RS00010
gene id: 1226968:A6A40_RS00010
uniprot id: A0A160JCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1226968:A6A40 RS02570
gene id: 1226968:A6A40_RS02570
uniprot id: A0A160JEH0
names: Similarity
messages: Belongs to the peptidase M16 family.

1226968:A6A40 RS03915
gene id: 1226968:A6A40_RS03915
uniprot id: A0A168Y2F9
names: Similarity
messages: Belongs to the GSP E family.

1226968:A6A40 RS07510
gene id: 1226968:A6A40_RS07510
uniprot id: A0A160JFT4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1226968:A6A40 RS07320
gene id: 1226968:A6A40_RS07320
uniprot id: A0A160JFT9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1226968:A6A40 RS14510
gene id: 1226968:A6A40_RS14510
uniprot id: A0A160JII4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS11060
gene id: 1226968:A6A40_RS11060
uniprot id: A0A160JHA7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1226968:A6A40 RS05935
gene id: 1226968:A6A40_RS05935
uniprot id: A0A160JF38
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1226968:A6A40 RS14190
gene id: 1226968:A6A40_RS14190
uniprot id: A0A160JIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1226968:A6A40 RS09430
gene id: 1226968:A6A40_RS09430
uniprot id: A0A160JGK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1226968:A6A40 RS04895
gene id: 1226968:A6A40_RS04895
uniprot id: A0A160JEN6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS03650
gene id: 1226968:A6A40_RS03650
uniprot id: A0A160JE61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1226968:A6A40 RS07520
gene id: 1226968:A6A40_RS07520
uniprot id: A0A160JFR6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1226968:A6A40 RS12610
gene id: 1226968:A6A40_RS12610
uniprot id: A0A160JHU2
names: Similarity
messages: Belongs to the creatininase superfamily.

1226968:A6A40 RS13210
gene id: 1226968:A6A40_RS13210
uniprot id: A0A161JHI6
names: Subcellular Location Annotation
messages: Cell inner membrane

1226968:A6A40 RS02950
gene id: 1226968:A6A40_RS02950
uniprot id: A0A160JEM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1226968:A6A40 RS11440
gene id: 1226968:A6A40_RS11440
uniprot id: A0A160JHD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1226968:A6A40 RS04650
gene id: 1226968:A6A40_RS04650
uniprot id: A0A161JGZ7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1226968:A6A40 RS14035
gene id: 1226968:A6A40_RS14035
uniprot id: A0A160JIE8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1226968:A6A40 RS05745
gene id: 1226968:A6A40_RS05745
uniprot id: A0A160JF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1226968:A6A40 RS08705
gene id: 1226968:A6A40_RS08705
uniprot id: A0A160JGW9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS06470
gene id: 1226968:A6A40_RS06470
uniprot id: A0A160JFD1
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS08710
gene id: 1226968:A6A40_RS08710
uniprot id: A0A160JG98
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1226968:A6A40 RS03740
gene id: 1226968:A6A40_RS03740
uniprot id: A0A160JE89
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1226968:A6A40 RS05760
gene id: 1226968:A6A40_RS05760
uniprot id: A0A160JFR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1226968:A6A40 RS12675
gene id: 1226968:A6A40_RS12675
uniprot id: A0A168YAI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS06530
gene id: 1226968:A6A40_RS06530
uniprot id: A0A160JFD9
names: Similarity
messages: Belongs to the SlyX family.

1226968:A6A40 RS07475
gene id: 1226968:A6A40_RS07475
uniprot id: A0A160JFQ7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1226968:A6A40 RS14665
gene id: 1226968:A6A40_RS14665
uniprot id: A0A160JIK8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1226968:A6A40 RS01875
gene id: 1226968:A6A40_RS01875
uniprot id: A0A160JDL2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1226968:A6A40 RS09080
gene id: 1226968:A6A40_RS09080
uniprot id: A0A160JGH5
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

1226968:A6A40 RS01915
gene id: 1226968:A6A40_RS01915
uniprot id: A0A160JE67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1226968:A6A40 RS01410
gene id: 1226968:A6A40_RS01410
uniprot id: A0A160JIM9
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1226968:A6A40 RS13265
gene id: 1226968:A6A40_RS13265
uniprot id: A0A160JIL0
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1226968:A6A40 RS04835
gene id: 1226968:A6A40_RS04835
uniprot id: A0A160JEP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS00580
gene id: 1226968:A6A40_RS00580
uniprot id: A0A168XZ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1226968:A6A40 RS01455
gene id: 1226968:A6A40_RS01455
uniprot id: A0A160JIR5
names: Similarity
messages: Belongs to the Gfa family.

1226968:A6A40 RS06895
gene id: 1226968:A6A40_RS06895
uniprot id: A0A160JFH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1226968:A6A40 RS13640
gene id: 1226968:A6A40_RS13640
uniprot id: A0A160JI94
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS12765
gene id: 1226968:A6A40_RS12765
uniprot id: A0A168YAL9
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1226968:A6A40 RS00390
gene id: 1226968:A6A40_RS00390
uniprot id: A0A160JCV1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1226968:A6A40 RS06755
gene id: 1226968:A6A40_RS06755
uniprot id: A0A160JFH3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1226968:A6A40 RS08830
gene id: 1226968:A6A40_RS08830
uniprot id: A0A160JGA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1226968:A6A40 RS06325
gene id: 1226968:A6A40_RS06325
uniprot id: A0A160JF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1226968:A6A40 RS05230
gene id: 1226968:A6A40_RS05230
uniprot id: A0A160JET6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1226968:A6A40 RS01920
gene id: 1226968:A6A40_RS01920
uniprot id: A0A160JDH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1226968:A6A40 RS12210
gene id: 1226968:A6A40_RS12210
uniprot id: A0A160JHN0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1226968:A6A40 RS06605
gene id: 1226968:A6A40_RS06605
uniprot id: A0A160JFD8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1226968:A6A40 RS05930
gene id: 1226968:A6A40_RS05930
uniprot id: A0A160JFT3
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS00815
gene id: 1226968:A6A40_RS00815
uniprot id: A0A160JD65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1226968:A6A40 RS10205
gene id: 1226968:A6A40_RS10205
uniprot id: A0A160JGV1
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS00445
gene id: 1226968:A6A40_RS00445
uniprot id: A0A160JCV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1226968:A6A40 RS13810
gene id: 1226968:A6A40_RS13810
uniprot id: A0A161JHK2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1226968:A6A40 RS09820
gene id: 1226968:A6A40_RS09820
uniprot id: A0A160JGP3
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1226968:A6A40 RS14670
gene id: 1226968:A6A40_RS14670
uniprot id: A0A160JIN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS04550
gene id: 1226968:A6A40_RS04550
uniprot id: A0A160JEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1226968:A6A40 RS07435
gene id: 1226968:A6A40_RS07435
uniprot id: A0A160JFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1226968:A6A40 RS12410
gene id: 1226968:A6A40_RS12410
uniprot id: A0A168YAC2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1226968:A6A40 RS02410
gene id: 1226968:A6A40_RS02410
uniprot id: A0A160JDT9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS06440
gene id: 1226968:A6A40_RS06440
uniprot id: A0A160JFB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1226968:A6A40 RS09640
gene id: 1226968:A6A40_RS09640
uniprot id: A0A160JGL8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1226968:A6A40 RS11200
gene id: 1226968:A6A40_RS11200
uniprot id: A0A168Y9B6
names: PTM
messages: Binds 1 heme group per subunit.

1226968:A6A40 RS13630
gene id: 1226968:A6A40_RS13630
uniprot id: A0A160JIQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1226968:A6A40 RS13330
gene id: 1226968:A6A40_RS13330
uniprot id: A0A160JIL3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1226968:A6A40 RS08295
gene id: 1226968:A6A40_RS08295
uniprot id: A0A160JG39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS13325
gene id: 1226968:A6A40_RS13325
uniprot id: A0A160JI35
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1226968:A6A40 RS13715
gene id: 1226968:A6A40_RS13715
uniprot id: A0A160JIB1
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS04455
gene id: 1226968:A6A40_RS04455
uniprot id: A0A168Y329
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS00800
gene id: 1226968:A6A40_RS00800
uniprot id: A0A160JD11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1226968:A6A40 RS12145
gene id: 1226968:A6A40_RS12145
uniprot id: A0A168YA16
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1226968:A6A40 RS04820
gene id: 1226968:A6A40_RS04820
uniprot id: A0A160JIS6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1226968:A6A40 RS07505
gene id: 1226968:A6A40_RS07505
uniprot id: A0A160JFS9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1226968:A6A40 RS06320
gene id: 1226968:A6A40_RS06320
uniprot id: A0A160JFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1226968:A6A40 RS01810
gene id: 1226968:A6A40_RS01810
uniprot id: A0A160JDE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1226968:A6A40 RS12830
gene id: 1226968:A6A40_RS12830
uniprot id: A0A160JHW8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1226968:A6A40 RS12155
gene id: 1226968:A6A40_RS12155
uniprot id: A0A161IUL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1226968:A6A40 RS13280
gene id: 1226968:A6A40_RS13280
uniprot id: A0A160JI49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1226968:A6A40 RS03340
gene id: 1226968:A6A40_RS03340
uniprot id: A0A168Y1W8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS14375
gene id: 1226968:A6A40_RS14375
uniprot id: A0A160JIG4
names: Similarity
messages: Belongs to the IlvD/Edd family.

1226968:A6A40 RS12300
gene id: 1226968:A6A40_RS12300
uniprot id: A0A168YDU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1226968:A6A40 RS10755
gene id: 1226968:A6A40_RS10755
uniprot id: A0A160JH29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1226968:A6A40 RS02840
gene id: 1226968:A6A40_RS02840
uniprot id: A0A160JDU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1226968:A6A40 RS07685
gene id: 1226968:A6A40_RS07685
uniprot id: A0A160JGG4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1226968:A6A40 RS05585
gene id: 1226968:A6A40_RS05585
uniprot id: A0A160JEY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1226968:A6A40 RS09115
gene id: 1226968:A6A40_RS09115
uniprot id: A0A160JH22
names: Similarity
messages: Belongs to the NifZ family.

1226968:A6A40 RS06420
gene id: 1226968:A6A40_RS06420
uniprot id: A0A161IUJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1226968:A6A40 RS11850
gene id: 1226968:A6A40_RS11850
uniprot id: A0A168Y9S0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS04105
gene id: 1226968:A6A40_RS04105
uniprot id: A0A160JF36
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1226968:A6A40 RS12440
gene id: 1226968:A6A40_RS12440
uniprot id: A0A160JHR7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS02070
gene id: 1226968:A6A40_RS02070
uniprot id: A0A160JDI9
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1226968:A6A40 RS05465
gene id: 1226968:A6A40_RS05465
uniprot id: A0A161IPX4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS03425
gene id: 1226968:A6A40_RS03425
uniprot id: A0A160JE31
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1226968:A6A40 RS11030
gene id: 1226968:A6A40_RS11030
uniprot id: A0A160JJ47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS07660
gene id: 1226968:A6A40_RS07660
uniprot id: A0A160JFW8
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1226968:A6A40 RS05175
gene id: 1226968:A6A40_RS05175
uniprot id: A0A161IPW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS09580
gene id: 1226968:A6A40_RS09580
uniprot id: A0A160JGL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1226968:A6A40 RS07530
gene id: 1226968:A6A40_RS07530
uniprot id: A0A160JGE0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1226968:A6A40 RS00475
gene id: 1226968:A6A40_RS00475
uniprot id: A0A160JCW4
names: Similarity
messages: Belongs to the pirin family.

1226968:A6A40 RS04630
gene id: 1226968:A6A40_RS04630
uniprot id: A0A160JFB7
names: Similarity
messages: Belongs to the citrate synthase family.

1226968:A6A40 RS00780
gene id: 1226968:A6A40_RS00780
uniprot id: A0A160JD10
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS13525
gene id: 1226968:A6A40_RS13525
uniprot id: A0A161JHJ3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1226968:A6A40 RS07535
gene id: 1226968:A6A40_RS07535
uniprot id: A0A160JFS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1226968:A6A40 RS08530
gene id: 1226968:A6A40_RS08530
uniprot id: A0A160JGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS09155
gene id: 1226968:A6A40_RS09155
uniprot id: A0A161JBG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1226968:A6A40 RS14045
gene id: 1226968:A6A40_RS14045
uniprot id: A0A160JIC9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1226968:A6A40 RS01845
gene id: 1226968:A6A40_RS01845
uniprot id: A0A160JDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1226968:A6A40 RS06575
gene id: 1226968:A6A40_RS06575
uniprot id: A0A160JFC7
names: Similarity
messages: Belongs to the CutA family.

1226968:A6A40 RS06785
gene id: 1226968:A6A40_RS06785
uniprot id: A0A160JFK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS08865
gene id: 1226968:A6A40_RS08865
uniprot id: A0A160JGE3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS07055
gene id: 1226968:A6A40_RS07055
uniprot id: A0A168Y5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1226968:A6A40 RS12655
gene id: 1226968:A6A40_RS12655
uniprot id: A0A161IUC6
names: Similarity
messages: Belongs to the UPF0102 family.

1226968:A6A40 RS00265
gene id: 1226968:A6A40_RS00265
uniprot id: A0A160JCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1226968:A6A40 RS00810
gene id: 1226968:A6A40_RS00810
uniprot id: A0A160JD22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1226968:A6A40 RS12015
gene id: 1226968:A6A40_RS12015
uniprot id: A0A160JHK9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1226968:A6A40 RS00690
gene id: 1226968:A6A40_RS00690
uniprot id: A0A160JCY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1226968:A6A40 RS01530
gene id: 1226968:A6A40_RS01530
uniprot id: A0A160JDG2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1226968:A6A40 RS04410
gene id: 1226968:A6A40_RS04410
uniprot id: A0A160JEG2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1226968:A6A40 RS00840
gene id: 1226968:A6A40_RS00840
uniprot id: A0A168XZE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1226968:A6A40 RS00875
gene id: 1226968:A6A40_RS00875
uniprot id: A0A160JD16
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1226968:A6A40 RS00895
gene id: 1226968:A6A40_RS00895
uniprot id: A0A168XZH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1226968:A6A40 RS06610
gene id: 1226968:A6A40_RS06610
uniprot id: A0A160JFC8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1226968:A6A40 RS03595
gene id: 1226968:A6A40_RS03595
uniprot id: A0A160JEX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1226968:A6A40 RS10380
gene id: 1226968:A6A40_RS10380
uniprot id: A0A160JH09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1226968:A6A40 RS00185
gene id: 1226968:A6A40_RS00185
uniprot id: A0A160JCY0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1226968:A6A40 RS04950
gene id: 1226968:A6A40_RS04950
uniprot id: A0A161JB86
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1226968:A6A40 RS01050
gene id: 1226968:A6A40_RS01050
uniprot id: A0A160JD98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1226968:A6A40 RS04995
gene id: 1226968:A6A40_RS04995
uniprot id: A0A160JES0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1226968:A6A40 RS10850
gene id: 1226968:A6A40_RS10850
uniprot id: A0A161JBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS12190
gene id: 1226968:A6A40_RS12190
uniprot id: A0A160JHM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS03465
gene id: 1226968:A6A40_RS03465
uniprot id: A0A160JE28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS00655
gene id: 1226968:A6A40_RS00655
uniprot id: A0A160JCY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1226968:A6A40 RS12495
gene id: 1226968:A6A40_RS12495
uniprot id: A0A160JHR5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1226968:A6A40 RS04095
gene id: 1226968:A6A40_RS04095
uniprot id: A0A160JIR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1226968:A6A40 RS04690
gene id: 1226968:A6A40_RS04690
uniprot id: A0A160JEK1
names: Subcellular Location Annotation
messages: Cell membrane

1226968:A6A40 RS08225
gene id: 1226968:A6A40_RS08225
uniprot id: A0A160JG29
names: Similarity
messages: Belongs to the oxoprolinase family.

1226968:A6A40 RS21055
gene id: 1226968:A6A40_RS21055
uniprot id: A0A2R4VSV3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1226968:A6A40 RS02675
gene id: 1226968:A6A40_RS02675
uniprot id: A0A160JDS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1226968:A6A40 RS08820
gene id: 1226968:A6A40_RS08820
uniprot id: A0A161IQ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1226968:A6A40 RS13830
gene id: 1226968:A6A40_RS13830
uniprot id: A0A160JIC7
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS00940
gene id: 1226968:A6A40_RS00940
uniprot id: A0A160JD82
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS13365
gene id: 1226968:A6A40_RS13365
uniprot id: A0A160JI72
names: Similarity
messages: Belongs to the leucine-binding protein family.

1226968:A6A40 RS05955
gene id: 1226968:A6A40_RS05955
uniprot id: A0A160JF56
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1226968:A6A40 RS03370
gene id: 1226968:A6A40_RS03370
uniprot id: A0A160JE23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1226968:A6A40 RS04800
gene id: 1226968:A6A40_RS04800
uniprot id: A0A160JFE0
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS10770
gene id: 1226968:A6A40_RS10770
uniprot id: A0A160JH25
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1226968:A6A40 RS08335
gene id: 1226968:A6A40_RS08335
uniprot id: A0A160JG66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1226968:A6A40 RS12375
gene id: 1226968:A6A40_RS12375
uniprot id: A0A168YAA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1226968:A6A40 RS04480
gene id: 1226968:A6A40_RS04480
uniprot id: A0A160JEN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1226968:A6A40 RS10615
gene id: 1226968:A6A40_RS10615
uniprot id: A0A161IU72
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1226968:A6A40 RS06730
gene id: 1226968:A6A40_RS06730
uniprot id: A0A160JFF3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1226968:A6A40 RS06050
gene id: 1226968:A6A40_RS06050
uniprot id: A0A160JFA5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS12400
gene id: 1226968:A6A40_RS12400
uniprot id: A0A160JHQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1226968:A6A40 RS09515
gene id: 1226968:A6A40_RS09515
uniprot id: A0A160JH73
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1226968:A6A40 RS10675
gene id: 1226968:A6A40_RS10675
uniprot id: A0A168Y8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS12265
gene id: 1226968:A6A40_RS12265
uniprot id: A0A161IQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1226968:A6A40 RS08110
gene id: 1226968:A6A40_RS08110
uniprot id: A0A160JG12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1226968:A6A40 RS11330
gene id: 1226968:A6A40_RS11330
uniprot id: A0A160JHW4
names: Similarity
messages: Belongs to the GST superfamily.

1226968:A6A40 RS07645
gene id: 1226968:A6A40_RS07645
uniprot id: A0A168Y648
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1226968:A6A40 RS08490
gene id: 1226968:A6A40_RS08490
uniprot id: A0A168Y6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1226968:A6A40 RS01795
gene id: 1226968:A6A40_RS01795
uniprot id: A0A160JDF6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1226968:A6A40 RS10040
gene id: 1226968:A6A40_RS10040
uniprot id: A0A160JGS3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1226968:A6A40 RS12460
gene id: 1226968:A6A40_RS12460
uniprot id: A0A168YAE8
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

1226968:A6A40 RS04540
gene id: 1226968:A6A40_RS04540
uniprot id: A0A168Y379
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS13035
gene id: 1226968:A6A40_RS13035
uniprot id: A0A160JHZ6
names: Similarity
messages: Belongs to the type III secretion exporter family.

1226968:A6A40 RS09265
gene id: 1226968:A6A40_RS09265
uniprot id: A0A160JGJ9
names: Similarity
messages: Belongs to the peptidase U62 family.

1226968:A6A40 RS01275
gene id: 1226968:A6A40_RS01275
uniprot id: A0A161JGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1226968:A6A40 RS00530
gene id: 1226968:A6A40_RS00530
uniprot id: A0A160JCX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1226968:A6A40 RS02245
gene id: 1226968:A6A40_RS02245
uniprot id: A0A160JDK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1226968:A6A40 RS01365
gene id: 1226968:A6A40_RS01365
uniprot id: A0A161ITD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS08395
gene id: 1226968:A6A40_RS08395
uniprot id: A0A160JG75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1226968:A6A40 RS11085
gene id: 1226968:A6A40_RS11085
uniprot id: A0A160JHB7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS02195
gene id: 1226968:A6A40_RS02195
uniprot id: A0A160JDK0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1226968:A6A40 RS01830
gene id: 1226968:A6A40_RS01830
uniprot id: A0A168Y0D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1226968:A6A40 RS02970
gene id: 1226968:A6A40_RS02970
uniprot id: A0A161JGV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS00465
gene id: 1226968:A6A40_RS00465
uniprot id: A0A160JD17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1226968:A6A40 RS04655
gene id: 1226968:A6A40_RS04655
uniprot id: A0A160JEK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1226968:A6A40 RS03590
gene id: 1226968:A6A40_RS03590
uniprot id: A0A160JE47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1226968:A6A40 RS11020
gene id: 1226968:A6A40_RS11020
uniprot id: A0A160JHA8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1226968:A6A40 RS12865
gene id: 1226968:A6A40_RS12865
uniprot id: A0A160JHZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1226968:A6A40 RS02860
gene id: 1226968:A6A40_RS02860
uniprot id: A0A168Y1D7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1226968:A6A40 RS03435
gene id: 1226968:A6A40_RS03435
uniprot id: A0A168Y229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1226968:A6A40 RS06220
gene id: 1226968:A6A40_RS06220
uniprot id: A0A168Y4T9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1226968:A6A40 RS03335
gene id: 1226968:A6A40_RS03335
uniprot id: A0A160JE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS01790
gene id: 1226968:A6A40_RS01790
uniprot id: A0A160JDF0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1226968:A6A40 RS05725
gene id: 1226968:A6A40_RS05725
uniprot id: A0A160JF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1226968:A6A40 RS09570
gene id: 1226968:A6A40_RS09570
uniprot id: A0A160JGK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1226968:A6A40 RS08355
gene id: 1226968:A6A40_RS08355
uniprot id: A0A160JG43
names: Similarity
messages: Belongs to the hemerythrin family.

1226968:A6A40 RS02605
gene id: 1226968:A6A40_RS02605
uniprot id: A0A168Y159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Membrane

1226968:A6A40 RS13555
gene id: 1226968:A6A40_RS13555
uniprot id: A0A161IQN5
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1226968:A6A40 RS02990
gene id: 1226968:A6A40_RS02990
uniprot id: A0A160JDY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1226968:A6A40 RS02750
gene id: 1226968:A6A40_RS02750
uniprot id: A0A160JDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1226968:A6A40 RS11965
gene id: 1226968:A6A40_RS11965
uniprot id: A0A160JHJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1226968:A6A40 RS14165
gene id: 1226968:A6A40_RS14165
uniprot id: A0A160JIE4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS08175
gene id: 1226968:A6A40_RS08175
uniprot id: A0A168Y6J9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1226968:A6A40 RS05625
gene id: 1226968:A6A40_RS05625
uniprot id: A0A160JEZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1226968:A6A40 RS07275
gene id: 1226968:A6A40_RS07275
uniprot id: A0A160JFP2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1226968:A6A40 RS07195
gene id: 1226968:A6A40_RS07195
uniprot id: A0A160JG89
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1226968:A6A40 RS08465
gene id: 1226968:A6A40_RS08465
uniprot id: A0A160JG62
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS10190
gene id: 1226968:A6A40_RS10190
uniprot id: A0A168Y8F1
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1226968:A6A40 RS13015
gene id: 1226968:A6A40_RS13015
uniprot id: A0A160JHY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1226968:A6A40 RS13225
gene id: 1226968:A6A40_RS13225
uniprot id: A0A160JI55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1226968:A6A40 RS02625
gene id: 1226968:A6A40_RS02625
uniprot id: A0A160JEH6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS10515
gene id: 1226968:A6A40_RS10515
uniprot id: A0A161IQ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1226968:A6A40 RS08885
gene id: 1226968:A6A40_RS08885
uniprot id: A0A160JGB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1226968:A6A40 RS10185
gene id: 1226968:A6A40_RS10185
uniprot id: A0A160JGY2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS01800
gene id: 1226968:A6A40_RS01800
uniprot id: A0A168Y0C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1226968:A6A40 RS14415
gene id: 1226968:A6A40_RS14415
uniprot id: A0A161JHL5
names: Similarity
messages: Belongs to the universal stress protein A family.

1226968:A6A40 RS08000
gene id: 1226968:A6A40_RS08000
uniprot id: A0A160JIW7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1226968:A6A40 RS01020
gene id: 1226968:A6A40_RS01020
uniprot id: A0A160JD56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1226968:A6A40 RS01385
gene id: 1226968:A6A40_RS01385
uniprot id: A0A168XZT4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS02225
gene id: 1226968:A6A40_RS02225
uniprot id: A0A160JDK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

1226968:A6A40 RS09865
gene id: 1226968:A6A40_RS09865
uniprot id: A0A160JGS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1226968:A6A40 RS08370
gene id: 1226968:A6A40_RS08370
uniprot id: A0A160JG80
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1226968:A6A40 RS13160
gene id: 1226968:A6A40_RS13160
uniprot id: A0A160JI05
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1226968:A6A40 RS02735
gene id: 1226968:A6A40_RS02735
uniprot id: A0A160JDS8
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1226968:A6A40 RS08890
gene id: 1226968:A6A40_RS08890
uniprot id: A0A160JGZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS02370
gene id: 1226968:A6A40_RS02370
uniprot id: A0A160JDM8
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS12435
gene id: 1226968:A6A40_RS12435
uniprot id: A0A160JHQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1226968:A6A40 RS01470
gene id: 1226968:A6A40_RS01470
uniprot id: A0A160JDA9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1226968:A6A40 RS10000
gene id: 1226968:A6A40_RS10000
uniprot id: A0A160JGR7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1226968:A6A40 RS14685
gene id: 1226968:A6A40_RS14685
uniprot id: A0A160JIK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1226968:A6A40 RS11805
gene id: 1226968:A6A40_RS11805
uniprot id: A0A160JI27
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS11685
gene id: 1226968:A6A40_RS11685
uniprot id: A0A160JHF4
names: Similarity
messages: Belongs to the NadC/ModD family.

1226968:A6A40 RS13835
gene id: 1226968:A6A40_RS13835
uniprot id: A0A161JBQ0
names: Similarity
messages: Belongs to the hemerythrin family.

1226968:A6A40 RS07425
gene id: 1226968:A6A40_RS07425
uniprot id: A0A160JGC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1226968:A6A40 RS01730
gene id: 1226968:A6A40_RS01730
uniprot id: A0A168Y091
names: Similarity
messages: Belongs to the leucine-binding protein family.

1226968:A6A40 RS12075
gene id: 1226968:A6A40_RS12075
uniprot id: A0A160JHQ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS04390
gene id: 1226968:A6A40_RS04390
uniprot id: A0A160JEI7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1226968:A6A40 RS04310
gene id: 1226968:A6A40_RS04310
uniprot id: A0A160JEE6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1226968:A6A40 RS08075
gene id: 1226968:A6A40_RS08075
uniprot id: A0A160JG06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1226968:A6A40 RS05580
gene id: 1226968:A6A40_RS05580
uniprot id: A0A160JFP6
names: Similarity
messages: Belongs to the virb1 family.

1226968:A6A40 RS07305
gene id: 1226968:A6A40_RS07305
uniprot id: A0A168YD63
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1226968:A6A40 RS09905
gene id: 1226968:A6A40_RS09905
uniprot id: A0A160JJ28
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS07145
gene id: 1226968:A6A40_RS07145
uniprot id: A0A160JFM0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1226968:A6A40 RS01855
gene id: 1226968:A6A40_RS01855
uniprot id: A0A160JDE0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1226968:A6A40 RS12710
gene id: 1226968:A6A40_RS12710
uniprot id: A0A168YAK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1226968:A6A40 RS06570
gene id: 1226968:A6A40_RS06570
uniprot id: A0A168Y558
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1226968:A6A40 RS06005
gene id: 1226968:A6A40_RS06005
uniprot id: A0A160JF48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1226968:A6A40 RS01090
gene id: 1226968:A6A40_RS01090
uniprot id: A0A160JD50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1226968:A6A40 RS09485
gene id: 1226968:A6A40_RS09485
uniprot id: A0A160JGL3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS00420
gene id: 1226968:A6A40_RS00420
uniprot id: A0A160JIP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS09655
gene id: 1226968:A6A40_RS09655
uniprot id: A0A160JGQ6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1226968:A6A40 RS08805
gene id: 1226968:A6A40_RS08805
uniprot id: A0A160JGB4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1226968:A6A40 RS04780
gene id: 1226968:A6A40_RS04780
uniprot id: A0A160JEP1
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS14435
gene id: 1226968:A6A40_RS14435
uniprot id: A0A160JIK5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1226968:A6A40 RS09950
gene id: 1226968:A6A40_RS09950
uniprot id: A0A160JGU8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1226968:A6A40 RS05905
gene id: 1226968:A6A40_RS05905
uniprot id: A0A160JF51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1226968:A6A40 RS02400
gene id: 1226968:A6A40_RS02400
uniprot id: A0A160JEE2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1226968:A6A40 RS01105
gene id: 1226968:A6A40_RS01105
uniprot id: A0A160JDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1226968:A6A40 RS08770
gene id: 1226968:A6A40_RS08770
uniprot id: A0A160JGX7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS00395
gene id: 1226968:A6A40_RS00395
uniprot id: A0A160JCV6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1226968:A6A40 RS04520
gene id: 1226968:A6A40_RS04520
uniprot id: A0A160JFA0
names: Similarity
messages: Belongs to the YicC/YloC family.

1226968:A6A40 RS01805
gene id: 1226968:A6A40_RS01805
uniprot id: A0A160JDD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1226968:A6A40 RS01480
gene id: 1226968:A6A40_RS01480
uniprot id: A0A168Y004
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1226968:A6A40 RS06500
gene id: 1226968:A6A40_RS06500
uniprot id: A0A160JFC2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1226968:A6A40 RS06360
gene id: 1226968:A6A40_RS06360
uniprot id: A0A161JBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1226968:A6A40 RS07675
gene id: 1226968:A6A40_RS07675
uniprot id: A0A160JFU3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1226968:A6A40 RS02905
gene id: 1226968:A6A40_RS02905
uniprot id: A0A160JDW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1226968:A6A40 RS04515
gene id: 1226968:A6A40_RS04515
uniprot id: A0A160JEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1226968:A6A40 RS01860
gene id: 1226968:A6A40_RS01860
uniprot id: A0A160JDF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1226968:A6A40 RS12825
gene id: 1226968:A6A40_RS12825
uniprot id: A0A160JHV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1226968:A6A40 RS13735
gene id: 1226968:A6A40_RS13735
uniprot id: A0A160JIS2
names: Similarity
messages: Belongs to the citrate synthase family.

1226968:A6A40 RS05685
gene id: 1226968:A6A40_RS05685
uniprot id: A0A160JFR2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1226968:A6A40 RS10375
gene id: 1226968:A6A40_RS10375
uniprot id: A0A160JGW8
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

1226968:A6A40 RS05630
gene id: 1226968:A6A40_RS05630
uniprot id: A0A160JEZ2
names: Similarity
messages: Belongs to the GcvT family.

1226968:A6A40 RS09645
gene id: 1226968:A6A40_RS09645
uniprot id: A0A160JH88
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1226968:A6A40 RS13130
gene id: 1226968:A6A40_RS13130
uniprot id: A0A160JI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS06260
gene id: 1226968:A6A40_RS06260
uniprot id: A0A160JF82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS05490
gene id: 1226968:A6A40_RS05490
uniprot id: A0A160JF27
names: Similarity
messages: Belongs to the Gfa family.

1226968:A6A40 RS06805
gene id: 1226968:A6A40_RS06805
uniprot id: A0A160JFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1226968:A6A40 RS01260
gene id: 1226968:A6A40_RS01260
uniprot id: A0A160JDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1226968:A6A40 RS11580
gene id: 1226968:A6A40_RS11580
uniprot id: A0A168Y9L9
names: Similarity
messages: Belongs to the glutamate synthase family.

1226968:A6A40 RS07170
gene id: 1226968:A6A40_RS07170
uniprot id: A0A160JFN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1226968:A6A40 RS04580
gene id: 1226968:A6A40_RS04580
uniprot id: A0A160JEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1226968:A6A40 RS02205
gene id: 1226968:A6A40_RS02205
uniprot id: A0A160JDK4
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from FixA/FixB and reduces a quinone.
messages: Part of an electron transfer system.

1226968:A6A40 RS10115
gene id: 1226968:A6A40_RS10115
uniprot id: A0A168Y8A4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS08330
gene id: 1226968:A6A40_RS08330
uniprot id: A0A160JG46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1226968:A6A40 RS07625
gene id: 1226968:A6A40_RS07625
uniprot id: A0A160JFT2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1226968:A6A40 RS01550
gene id: 1226968:A6A40_RS01550
uniprot id: A0A160JDC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1226968:A6A40 RS03780
gene id: 1226968:A6A40_RS03780
uniprot id: A0A160JED5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1226968:A6A40 RS09280
gene id: 1226968:A6A40_RS09280
uniprot id: A0A160JGH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1226968:A6A40 RS06315
gene id: 1226968:A6A40_RS06315
uniprot id: A0A160JF87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1226968:A6A40 RS03430
gene id: 1226968:A6A40_RS03430
uniprot id: A0A160JE85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1226968:A6A40 RS08960
gene id: 1226968:A6A40_RS08960
uniprot id: A0A160JGG6
names: Similarity
messages: Belongs to the peptidase S41A family.

1226968:A6A40 RS12645
gene id: 1226968:A6A40_RS12645
uniprot id: A0A160JHT3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1226968:A6A40 RS00060
gene id: 1226968:A6A40_RS00060
uniprot id: A0A160JCQ9
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1226968:A6A40 RS04615
gene id: 1226968:A6A40_RS04615
uniprot id: A0A160JEJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1226968:A6A40 RS12275
gene id: 1226968:A6A40_RS12275
uniprot id: A0A160JJ71
names: Similarity
messages: Belongs to the Tim44 family.

1226968:A6A40 RS02995
gene id: 1226968:A6A40_RS02995
uniprot id: A0A161JB53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS00495
gene id: 1226968:A6A40_RS00495
uniprot id: A0A160JCW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1226968:A6A40 RS14025
gene id: 1226968:A6A40_RS14025
uniprot id: A0A160JIW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1226968:A6A40 RS08130
gene id: 1226968:A6A40_RS08130
uniprot id: A0A160JG07
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1226968:A6A40 RS06655
gene id: 1226968:A6A40_RS06655
uniprot id: A0A160JFE8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1226968:A6A40 RS05265
gene id: 1226968:A6A40_RS05265
uniprot id: A0A161ITP7
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1226968:A6A40 RS03945
gene id: 1226968:A6A40_RS03945
uniprot id: A0A168Y2H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

1226968:A6A40 RS10385
gene id: 1226968:A6A40_RS10385
uniprot id: A0A168Y8J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1226968:A6A40 RS02790
gene id: 1226968:A6A40_RS02790
uniprot id: A0A160JEK0
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1226968:A6A40 RS05650
gene id: 1226968:A6A40_RS05650
uniprot id: A0A168Y492
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1226968:A6A40 RS03330
gene id: 1226968:A6A40_RS03330
uniprot id: A0A160JE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1226968:A6A40 RS06065
gene id: 1226968:A6A40_RS06065
uniprot id: A0A160JF68
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS00350
gene id: 1226968:A6A40_RS00350
uniprot id: A0A160JCV3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1226968:A6A40 RS01110
gene id: 1226968:A6A40_RS01110
uniprot id: A0A168XZL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1226968:A6A40 RS05270
gene id: 1226968:A6A40_RS05270
uniprot id: A0A160JEU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1226968:A6A40 RS02815
gene id: 1226968:A6A40_RS02815
uniprot id: A0A160JDU2
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.

1226968:A6A40 RS09010
gene id: 1226968:A6A40_RS09010
uniprot id: A0A160JGH3
names: Subcellular Location Annotation
messages: Mitochondrion

1226968:A6A40 RS11625
gene id: 1226968:A6A40_RS11625
uniprot id: A0A160JHJ1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-65 and Arg-68) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1226968:A6A40 RS13995
gene id: 1226968:A6A40_RS13995
uniprot id: A0A160JIC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1226968:A6A40 RS00280
gene id: 1226968:A6A40_RS00280
uniprot id: A0A160JCT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1226968:A6A40 RS09380
gene id: 1226968:A6A40_RS09380
uniprot id: A0A160JGI4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS12995
gene id: 1226968:A6A40_RS12995
uniprot id: A0A160JHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm

1226968:A6A40 RS11640
gene id: 1226968:A6A40_RS11640
uniprot id: A0A160JHF7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1226968:A6A40 RS12380
gene id: 1226968:A6A40_RS12380
uniprot id: A0A160JHQ1
names: Similarity
messages: Belongs to the UPF0310 family.

1226968:A6A40 RS09810
gene id: 1226968:A6A40_RS09810
uniprot id: A0A160JGS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1226968:A6A40 RS02850
gene id: 1226968:A6A40_RS02850
uniprot id: A0A160JDU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1226968:A6A40 RS12100
gene id: 1226968:A6A40_RS12100
uniprot id: A0A160JHL2
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1226968:A6A40 RS08605
gene id: 1226968:A6A40_RS08605
uniprot id: A0A161IU03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1226968:A6A40 RS10775
gene id: 1226968:A6A40_RS10775
uniprot id: A0A160JH63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1226968:A6A40 RS21525
gene id: 1226968:A6A40_RS21525
uniprot id: A0A2R4VT60
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1226968:A6A40 RS07525
gene id: 1226968:A6A40_RS07525
uniprot id: A0A160JFR5
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS04375
gene id: 1226968:A6A40_RS04375
uniprot id: A0A160JEM3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1226968:A6A40 RS03505
gene id: 1226968:A6A40_RS03505
uniprot id: A0A160JE55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1226968:A6A40 RS14715
gene id: 1226968:A6A40_RS14715
uniprot id: A0A160JIP2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1226968:A6A40 RS06465
gene id: 1226968:A6A40_RS06465
uniprot id: A0A160JFC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1226968:A6A40 RS02775
gene id: 1226968:A6A40_RS02775
uniprot id: A0A168Y188
names: Similarity
messages: Belongs to the PhoH family.

1226968:A6A40 RS07135
gene id: 1226968:A6A40_RS07135
uniprot id: A0A160JFK6
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1226968:A6A40 RS14225
gene id: 1226968:A6A40_RS14225
uniprot id: A0A160JIF3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1226968:A6A40 RS01315
gene id: 1226968:A6A40_RS01315
uniprot id: A0A160JD84
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1226968:A6A40 RS07085
gene id: 1226968:A6A40_RS07085
uniprot id: A0A160JFJ8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1226968:A6A40 RS08300
gene id: 1226968:A6A40_RS08300
uniprot id: A0A160JG30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1226968:A6A40 RS03445
gene id: 1226968:A6A40_RS03445
uniprot id: A0A160JE51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1226968:A6A40 RS00030
gene id: 1226968:A6A40_RS00030
uniprot id: A0A160JCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1226968:A6A40 RS10790
gene id: 1226968:A6A40_RS10790
uniprot id: A0A160JH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1226968:A6A40 RS01270
gene id: 1226968:A6A40_RS01270
uniprot id: A0A160JDD0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1226968:A6A40 RS06630
gene id: 1226968:A6A40_RS06630
uniprot id: A0A161JH44
names: Similarity
messages: Belongs to the peptidase S49 family.

1226968:A6A40 RS08715
gene id: 1226968:A6A40_RS08715
uniprot id: A0A160JGD0
names: Similarity
messages: Belongs to the hemerythrin family.

1226968:A6A40 RS09910
gene id: 1226968:A6A40_RS09910
uniprot id: A0A160JGR2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1226968:A6A40 RS24905
gene id: 1226968:A6A40_RS24905
uniprot id: A0A2R4VV49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1226968:A6A40 RS14700
gene id: 1226968:A6A40_RS14700
uniprot id: A0A160JIP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1226968:A6A40 RS08500
gene id: 1226968:A6A40_RS08500
uniprot id: A0A160JG71
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1226968:A6A40 RS14530
gene id: 1226968:A6A40_RS14530
uniprot id: A0A160JIL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1226968:A6A40 RS07835
gene id: 1226968:A6A40_RS07835
uniprot id: A0A160JFZ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS11025
gene id: 1226968:A6A40_RS11025
uniprot id: A0A168Y997
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS11570
gene id: 1226968:A6A40_RS11570
uniprot id: A0A160JHE0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS00470
gene id: 1226968:A6A40_RS00470
uniprot id: A0A161ITA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS11705
gene id: 1226968:A6A40_RS11705
uniprot id: A0A160JHG6
names: Similarity
messages: Belongs to the YggT family.

1226968:A6A40 RS02555
gene id: 1226968:A6A40_RS02555
uniprot id: A0A160JDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1226968:A6A40 RS09735
gene id: 1226968:A6A40_RS09735
uniprot id: A0A160JGN9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1226968:A6A40 RS08755
gene id: 1226968:A6A40_RS08755
uniprot id: A0A168Y721
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1226968:A6A40 RS13300
gene id: 1226968:A6A40_RS13300
uniprot id: A0A160JI24
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS12845
gene id: 1226968:A6A40_RS12845
uniprot id: A0A160JHW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1226968:A6A40 RS10610
gene id: 1226968:A6A40_RS10610
uniprot id: A0A160JH39
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS13100
gene id: 1226968:A6A40_RS13100
uniprot id: A0A160JI04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1226968:A6A40 RS11690
gene id: 1226968:A6A40_RS11690
uniprot id: A0A160JHJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1226968:A6A40 RS07745
gene id: 1226968:A6A40_RS07745
uniprot id: A0A160JGH1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1226968:A6A40 RS02670
gene id: 1226968:A6A40_RS02670
uniprot id: A0A160JDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS08115
gene id: 1226968:A6A40_RS08115
uniprot id: A0A160JG35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1226968:A6A40 RS10430
gene id: 1226968:A6A40_RS10430
uniprot id: A0A160JGX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1226968:A6A40 RS08780
gene id: 1226968:A6A40_RS08780
uniprot id: A0A160JGD8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1226968:A6A40 RS10870
gene id: 1226968:A6A40_RS10870
uniprot id: A0A160JH46
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1226968:A6A40 RS01430
gene id: 1226968:A6A40_RS01430
uniprot id: A0A160JD85
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1226968:A6A40 RS11480
gene id: 1226968:A6A40_RS11480
uniprot id: A0A168Y9G1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1226968:A6A40 RS14315
gene id: 1226968:A6A40_RS14315
uniprot id: A0A168YCB1
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS13505
gene id: 1226968:A6A40_RS13505
uniprot id: A0A160JI48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1226968:A6A40 RS12535
gene id: 1226968:A6A40_RS12535
uniprot id: A0A160JJ38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1226968:A6A40 RS12350
gene id: 1226968:A6A40_RS12350
uniprot id: A0A160JHS8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1226968:A6A40 RS11780
gene id: 1226968:A6A40_RS11780
uniprot id: A0A160JHL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1226968:A6A40 RS03775
gene id: 1226968:A6A40_RS03775
uniprot id: A0A160JE80
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1226968:A6A40 RS04790
gene id: 1226968:A6A40_RS04790
uniprot id: A0A160JEM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1226968:A6A40 RS02880
gene id: 1226968:A6A40_RS02880
uniprot id: A0A168Y1G6
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1226968:A6A40 RS05640
gene id: 1226968:A6A40_RS05640
uniprot id: A0A160JEZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1226968:A6A40 RS10735
gene id: 1226968:A6A40_RS10735
uniprot id: A0A160JH28
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS14040
gene id: 1226968:A6A40_RS14040
uniprot id: A0A168YC25
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1226968:A6A40 RS02120
gene id: 1226968:A6A40_RS02120
uniprot id: A0A160JDI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1226968:A6A40 RS09630
gene id: 1226968:A6A40_RS09630
uniprot id: A0A160JGM1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS08845
gene id: 1226968:A6A40_RS08845
uniprot id: A0A160JGE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1226968:A6A40 RS10545
gene id: 1226968:A6A40_RS10545
uniprot id: A0A160JH31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1226968:A6A40 RS04055
gene id: 1226968:A6A40_RS04055
uniprot id: A0A168Y2Q1
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1226968:A6A40 RS02060
gene id: 1226968:A6A40_RS02060
uniprot id: A0A168Y0L3
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1226968:A6A40 RS20025
gene id: 1226968:A6A40_RS20025
uniprot id: A0A2R4VTJ3
names: Similarity
messages: Belongs to the UPF0145 family.

1226968:A6A40 RS06565
gene id: 1226968:A6A40_RS06565
uniprot id: A0A160JFH5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS03665
gene id: 1226968:A6A40_RS03665
uniprot id: A0A160JE64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1226968:A6A40 RS06100
gene id: 1226968:A6A40_RS06100
uniprot id: A0A160JFV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1226968:A6A40 RS09505
gene id: 1226968:A6A40_RS09505
uniprot id: A0A160JGK3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1226968:A6A40 RS02585
gene id: 1226968:A6A40_RS02585
uniprot id: A0A168Y143
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1226968:A6A40 RS04640
gene id: 1226968:A6A40_RS04640
uniprot id: A0A168YCX1
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS06865
gene id: 1226968:A6A40_RS06865
uniprot id: A0A160JFH8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1226968:A6A40 RS02250
gene id: 1226968:A6A40_RS02250
uniprot id: A0A160JDK6
names: Similarity
messages: Belongs to the HesB/IscA family.

1226968:A6A40 RS05225
gene id: 1226968:A6A40_RS05225
uniprot id: A0A161JB92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS05335
gene id: 1226968:A6A40_RS05335
uniprot id: A0A160JEW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1226968:A6A40 RS08600
gene id: 1226968:A6A40_RS08600
uniprot id: A0A160JGB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1226968:A6A40 RS09995
gene id: 1226968:A6A40_RS09995
uniprot id: A0A160JHD5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1226968:A6A40 RS11700
gene id: 1226968:A6A40_RS11700
uniprot id: A0A160JHG1
names: Similarity
messages: Belongs to the UPF0235 family.

1226968:A6A40 RS00380
gene id: 1226968:A6A40_RS00380
uniprot id: A0A160JCW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1226968:A6A40 RS11205
gene id: 1226968:A6A40_RS11205
uniprot id: A0A160JH91
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1226968:A6A40 RS12700
gene id: 1226968:A6A40_RS12700
uniprot id: A0A160JHU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1226968:A6A40 RS00740
gene id: 1226968:A6A40_RS00740
uniprot id: A0A160JCZ7
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS01645
gene id: 1226968:A6A40_RS01645
uniprot id: A0A160JDD2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1226968:A6A40 RS09160
gene id: 1226968:A6A40_RS09160
uniprot id: A0A160JGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1226968:A6A40 RS11565
gene id: 1226968:A6A40_RS11565
uniprot id: A0A160JHZ5
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS12600
gene id: 1226968:A6A40_RS12600
uniprot id: A0A161JHH3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1226968:A6A40 RS11380
gene id: 1226968:A6A40_RS11380
uniprot id: A0A160JHX4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1226968:A6A40 RS02740
gene id: 1226968:A6A40_RS02740
uniprot id: A0A160JEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1226968:A6A40 RS03365
gene id: 1226968:A6A40_RS03365
uniprot id: A0A160JEU0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1226968:A6A40 RS08090
gene id: 1226968:A6A40_RS08090
uniprot id: A0A160JG17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1226968:A6A40 RS14580
gene id: 1226968:A6A40_RS14580
uniprot id: A0A160JIN1
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS03640
gene id: 1226968:A6A40_RS03640
uniprot id: A0A160JE54
names: Similarity
messages: Belongs to the UPF0174 family.

1226968:A6A40 RS12120
gene id: 1226968:A6A40_RS12120
uniprot id: A0A160JHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1226968:A6A40 RS08575
gene id: 1226968:A6A40_RS08575
uniprot id: A0A160JJ03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1226968:A6A40 RS07840
gene id: 1226968:A6A40_RS07840
uniprot id: A0A168Y684
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1226968:A6A40 RS13120
gene id: 1226968:A6A40_RS13120
uniprot id: A0A160JJ46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1226968:A6A40 RS14405
gene id: 1226968:A6A40_RS14405
uniprot id: A0A160JIH8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1226968:A6A40 RS11500
gene id: 1226968:A6A40_RS11500
uniprot id: A0A160JHY7
names: Similarity
messages: Belongs to the aspartokinase family.

1226968:A6A40 RS12870
gene id: 1226968:A6A40_RS12870
uniprot id: A0A168YAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1226968:A6A40 RS01200
gene id: 1226968:A6A40_RS01200
uniprot id: A0A160JD67
names: Similarity
messages: Belongs to the UPF0229 family.

1226968:A6A40 RS00970
gene id: 1226968:A6A40_RS00970
uniprot id: A0A160JD45
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS00400
gene id: 1226968:A6A40_RS00400
uniprot id: A0A160JDL0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1226968:A6A40 RS00460
gene id: 1226968:A6A40_RS00460
uniprot id: A0A160JCW9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1226968:A6A40 RS10970
gene id: 1226968:A6A40_RS10970
uniprot id: A0A168Y988
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS14490
gene id: 1226968:A6A40_RS14490
uniprot id: A0A160JIM4
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1226968:A6A40 RS02910
gene id: 1226968:A6A40_RS02910
uniprot id: A0A160JE06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1226968:A6A40 RS08800
gene id: 1226968:A6A40_RS08800
uniprot id: A0A160JGB2
names: Similarity
messages: Belongs to the hemerythrin family.

1226968:A6A40 RS09175
gene id: 1226968:A6A40_RS09175
uniprot id: A0A160JGF7
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1226968:A6A40 RS07330
gene id: 1226968:A6A40_RS07330
uniprot id: A0A160JFP3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1226968:A6A40 RS11170
gene id: 1226968:A6A40_RS11170
uniprot id: A0A160JHC6
names: Similarity
messages: Belongs to the Dps family.

1226968:A6A40 RS07955
gene id: 1226968:A6A40_RS07955
uniprot id: A0A161IQ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1226968:A6A40 RS06615
gene id: 1226968:A6A40_RS06615
uniprot id: A0A160JG05
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS07360
gene id: 1226968:A6A40_RS07360
uniprot id: A0A160JFP1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1226968:A6A40 RS08375
gene id: 1226968:A6A40_RS08375
uniprot id: A0A168Y6P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1226968:A6A40 RS02230
gene id: 1226968:A6A40_RS02230
uniprot id: A0A160JDL7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1226968:A6A40 RS01565
gene id: 1226968:A6A40_RS01565
uniprot id: A0A160JDB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1226968:A6A40 RS07205
gene id: 1226968:A6A40_RS07205
uniprot id: A0A160JFS2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1226968:A6A40 RS10240
gene id: 1226968:A6A40_RS10240
uniprot id: A0A160JGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1226968:A6A40 RS13820
gene id: 1226968:A6A40_RS13820
uniprot id: A0A160JJ74
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1226968:A6A40 RS11095
gene id: 1226968:A6A40_RS11095
uniprot id: A0A160JH82
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS05405
gene id: 1226968:A6A40_RS05405
uniprot id: A0A160JEW5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1226968:A6A40 RS06890
gene id: 1226968:A6A40_RS06890
uniprot id: A0A161JH51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1226968:A6A40 RS08990
gene id: 1226968:A6A40_RS08990
uniprot id: A0A160JGD3
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS13535
gene id: 1226968:A6A40_RS13535
uniprot id: A0A160JI61
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1226968:A6A40 RS07830
gene id: 1226968:A6A40_RS07830
uniprot id: A0A160JFW9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1226968:A6A40 RS05890
gene id: 1226968:A6A40_RS05890
uniprot id: A0A168Y4F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1226968:A6A40 RS13705
gene id: 1226968:A6A40_RS13705
uniprot id: A0A160JI78
names: Subcellular Location Annotation
messages: Cell inner membrane

1226968:A6A40 RS06825
gene id: 1226968:A6A40_RS06825
uniprot id: A0A160JG36
names: Similarity
messages: Belongs to the MotB family.

1226968:A6A40 RS11795
gene id: 1226968:A6A40_RS11795
uniprot id: A0A160JHI2
names: Subcellular Location Annotation
messages: Cytoplasm

1226968:A6A40 RS14125
gene id: 1226968:A6A40_RS14125
uniprot id: A0A160JID2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1226968:A6A40 RS09005
gene id: 1226968:A6A40_RS09005
uniprot id: A0A160JGD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1226968:A6A40 RS13520
gene id: 1226968:A6A40_RS13520
uniprot id: A0A160JI73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS11180
gene id: 1226968:A6A40_RS11180
uniprot id: A0A160JH94
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS10845
gene id: 1226968:A6A40_RS10845
uniprot id: A0A160JH84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS02235
gene id: 1226968:A6A40_RS02235
uniprot id: A0A160JDM1
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1226968:A6A40 RS07990
gene id: 1226968:A6A40_RS07990
uniprot id: A0A161JH72
names: Subcellular Location Annotation
messages: Cell inner membrane

1226968:A6A40 RS07120
gene id: 1226968:A6A40_RS07120
uniprot id: A0A160JFM9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS09685
gene id: 1226968:A6A40_RS09685
uniprot id: A0A161IQ69
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1226968:A6A40 RS01605
gene id: 1226968:A6A40_RS01605
uniprot id: A0A161JB34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1226968:A6A40 RS08070
gene id: 1226968:A6A40_RS08070
uniprot id: A0A168Y6E0
names: Similarity
messages: Belongs to the GARS family.

1226968:A6A40 RS11770
gene id: 1226968:A6A40_RS11770
uniprot id: A0A160JHG9
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1226968:A6A40 RS03125
gene id: 1226968:A6A40_RS03125
uniprot id: A0A160JEQ7
names: Similarity
messages: Belongs to the MlaA family.

1226968:A6A40 RS07150
gene id: 1226968:A6A40_RS07150
uniprot id: A0A160JFR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1226968:A6A40 RS10390
gene id: 1226968:A6A40_RS10390
uniprot id: A0A160JGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1226968:A6A40 RS03180
gene id: 1226968:A6A40_RS03180
uniprot id: A0A160JE01
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.

1226968:A6A40 RS05010
gene id: 1226968:A6A40_RS05010
uniprot id: A0A160JEP8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1226968:A6A40 RS10865
gene id: 1226968:A6A40_RS10865
uniprot id: A0A160JHQ9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1226968:A6A40 RS08840
gene id: 1226968:A6A40_RS08840
uniprot id: A0A160JGB3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1226968:A6A40 RS07455
gene id: 1226968:A6A40_RS07455
uniprot id: A0A160JFS1
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1226968:A6A40 RS03980
gene id: 1226968:A6A40_RS03980
uniprot id: A0A160JF20
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1226968:A6A40 RS04575
gene id: 1226968:A6A40_RS04575
uniprot id: A0A160JFA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS10750
gene id: 1226968:A6A40_RS10750
uniprot id: A0A168Y8Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1226968:A6A40 RS12635
gene id: 1226968:A6A40_RS12635
uniprot id: A0A160JHU1
names: Similarity
messages: Belongs to the peptidase C15 family.

1226968:A6A40 RS06230
gene id: 1226968:A6A40_RS06230
uniprot id: A0A160JF92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1226968:A6A40 RS02940
gene id: 1226968:A6A40_RS02940
uniprot id: A0A160JDV9
names: Similarity
messages: Belongs to the ArsC family.

1226968:A6A40 RS13345
gene id: 1226968:A6A40_RS13345
uniprot id: A0A160JJ65
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1226968:A6A40 RS02580
gene id: 1226968:A6A40_RS02580
uniprot id: A0A160JDW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1226968:A6A40 RS01525
gene id: 1226968:A6A40_RS01525
uniprot id: A0A160JJ88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1226968:A6A40 RS03245
gene id: 1226968:A6A40_RS03245
uniprot id: A0A160JES2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1226968:A6A40 RS09270
gene id: 1226968:A6A40_RS09270
uniprot id: A0A168Y7I8
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS09340
gene id: 1226968:A6A40_RS09340
uniprot id: A0A160JH48
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1226968:A6A40 RS12465
gene id: 1226968:A6A40_RS12465
uniprot id: A0A160JHS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1226968:A6A40 RS11305
gene id: 1226968:A6A40_RS11305
uniprot id: A0A160JHE6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1226968:A6A40 RS30095
gene id: 1226968:A6A40_RS30095
uniprot id: A0A2R4VXS6
names: Similarity
messages: Belongs to the HesB/IscA family.

1226968:A6A40 RS01925
gene id: 1226968:A6A40_RS01925
uniprot id: A0A160JDM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1226968:A6A40 RS05795
gene id: 1226968:A6A40_RS05795
uniprot id: A0A160JF31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1226968:A6A40 RS11460
gene id: 1226968:A6A40_RS11460
uniprot id: A0A161IU95
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1226968:A6A40 RS12445
gene id: 1226968:A6A40_RS12445
uniprot id: A0A160JIA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1226968:A6A40 RS11605
gene id: 1226968:A6A40_RS11605
uniprot id: A0A160JHE8
names: Similarity
messages: Belongs to the peptidase M17 family.

1226968:A6A40 RS12820
gene id: 1226968:A6A40_RS12820
uniprot id: A0A168YAN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1226968:A6A40 RS05505
gene id: 1226968:A6A40_RS05505
uniprot id: A0A160JEZ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS09585
gene id: 1226968:A6A40_RS09585
uniprot id: A0A160JJ18
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1226968:A6A40 RS03265
gene id: 1226968:A6A40_RS03265
uniprot id: A0A160JE11
names: Similarity
messages: Belongs to the RecJ family.

1226968:A6A40 RS07630
gene id: 1226968:A6A40_RS07630
uniprot id: A0A160JGF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1226968:A6A40 RS08340
gene id: 1226968:A6A40_RS08340
uniprot id: A0A160JIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1226968:A6A40 RS00610
gene id: 1226968:A6A40_RS00610
uniprot id: A0A168XZ82
names: Similarity
messages: Belongs to the DinB family.

1226968:A6A40 RS07800
gene id: 1226968:A6A40_RS07800
uniprot id: A0A160JGI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1226968:A6A40 RS10585
gene id: 1226968:A6A40_RS10585
uniprot id: A0A160JH11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1226968:A6A40 RS05300
gene id: 1226968:A6A40_RS05300
uniprot id: A0A160JET8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1226968:A6A40 RS02425
gene id: 1226968:A6A40_RS02425
uniprot id: A0A160JDQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1226968:A6A40 RS13030
gene id: 1226968:A6A40_RS13030
uniprot id: A0A160JHZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1226968:A6A40 RS28315
gene id: 1226968:A6A40_RS28315
uniprot id: A0A2R4VWT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1226968:A6A40 RS07750
gene id: 1226968:A6A40_RS07750
uniprot id: A0A160JFX2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1226968:A6A40 RS13560
gene id: 1226968:A6A40_RS13560
uniprot id: A0A160JI69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS08325
gene id: 1226968:A6A40_RS08325
uniprot id: A0A160JG48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1226968:A6A40 RS00100
gene id: 1226968:A6A40_RS00100
uniprot id: A0A160JIP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1226968:A6A40 RS02885
gene id: 1226968:A6A40_RS02885
uniprot id: A0A160JDV3
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1226968:A6A40 RS04960
gene id: 1226968:A6A40_RS04960
uniprot id: A0A160JEN9
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS01100
gene id: 1226968:A6A40_RS01100
uniprot id: A0A160JD62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS03320
gene id: 1226968:A6A40_RS03320
uniprot id: A0A161ITI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1226968:A6A40 RS05085
gene id: 1226968:A6A40_RS05085
uniprot id: A0A160JES4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1226968:A6A40 RS02600
gene id: 1226968:A6A40_RS02600
uniprot id: A0A160JDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Membrane

1226968:A6A40 RS08290
gene id: 1226968:A6A40_RS08290
uniprot id: A0A161JBE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS11400
gene id: 1226968:A6A40_RS11400
uniprot id: A0A160JJ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1226968:A6A40 RS14050
gene id: 1226968:A6A40_RS14050
uniprot id: A0A160JIC8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1226968:A6A40 RS07230
gene id: 1226968:A6A40_RS07230
uniprot id: A0A168Y5N6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1226968:A6A40 RS03395
gene id: 1226968:A6A40_RS03395
uniprot id: A0A160JE41
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1226968:A6A40 RS11445
gene id: 1226968:A6A40_RS11445
uniprot id: A0A160JHX9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1226968:A6A40 RS08745
gene id: 1226968:A6A40_RS08745
uniprot id: A0A160JGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS12615
gene id: 1226968:A6A40_RS12615
uniprot id: A0A160JJ79
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1226968:A6A40 RS11275
gene id: 1226968:A6A40_RS11275
uniprot id: A0A160JHV8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1226968:A6A40 RS05290
gene id: 1226968:A6A40_RS05290
uniprot id: A0A168Y3S5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1226968:A6A40 RS04425
gene id: 1226968:A6A40_RS04425
uniprot id: A0A160JEN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1226968:A6A40 RS03275
gene id: 1226968:A6A40_RS03275
uniprot id: A0A160JJB2
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1226968:A6A40 RS13745
gene id: 1226968:A6A40_RS13745
uniprot id: A0A160JI95
names: Subcellular Location Annotation
messages: Cell inner membrane

1226968:A6A40 RS12105
gene id: 1226968:A6A40_RS12105
uniprot id: A0A160JHP8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1226968:A6A40 RS04705
gene id: 1226968:A6A40_RS04705
uniprot id: A0A160JER9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1226968:A6A40 RS12150
gene id: 1226968:A6A40_RS12150
uniprot id: A0A160JJ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1226968:A6A40 RS03905
gene id: 1226968:A6A40_RS03905
uniprot id: A0A160JEB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1226968:A6A40 RS00950
gene id: 1226968:A6A40_RS00950
uniprot id: A0A168XZI4
names: Similarity
messages: Belongs to the malate synthase family.

1226968:A6A40 RS08305
gene id: 1226968:A6A40_RS08305
uniprot id: A0A160JGQ7
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS04595
gene id: 1226968:A6A40_RS04595
uniprot id: A0A160JEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1226968:A6A40 RS13975
gene id: 1226968:A6A40_RS13975
uniprot id: A0A160JIW0
names: PTM
messages: Binds 1 heme group per subunit.

1226968:A6A40 RS07945
gene id: 1226968:A6A40_RS07945
uniprot id: A0A160JFY8
names: Similarity
messages: Belongs to the peptidase M24B family.

1226968:A6A40 RS01870
gene id: 1226968:A6A40_RS01870
uniprot id: A0A160JDG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1226968:A6A40 RS08410
gene id: 1226968:A6A40_RS08410
uniprot id: A0A160JG47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1226968:A6A40 RS06435
gene id: 1226968:A6A40_RS06435
uniprot id: A0A160JFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1226968:A6A40 RS02655
gene id: 1226968:A6A40_RS02655
uniprot id: A0A160JDT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1226968:A6A40 RS01890
gene id: 1226968:A6A40_RS01890
uniprot id: A0A160JDG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1226968:A6A40 RS10855
gene id: 1226968:A6A40_RS10855
uniprot id: A0A160JH44
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS04665
gene id: 1226968:A6A40_RS04665
uniprot id: A0A160JEM1
names: Similarity
messages: Belongs to the TrpC family.

1226968:A6A40 RS13915
gene id: 1226968:A6A40_RS13915
uniprot id: A0A160JID3
names: Similarity
messages: Belongs to the peptidase M20A family.

1226968:A6A40 RS09545
gene id: 1226968:A6A40_RS09545
uniprot id: A0A160JGM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1226968:A6A40 RS00385
gene id: 1226968:A6A40_RS00385
uniprot id: A0A161IPL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1226968:A6A40 RS07485
gene id: 1226968:A6A40_RS07485
uniprot id: A0A160JFR9
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS02545
gene id: 1226968:A6A40_RS02545
uniprot id: A0A168Y127
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS13720
gene id: 1226968:A6A40_RS13720
uniprot id: A0A168YBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1226968:A6A40 RS00080
gene id: 1226968:A6A40_RS00080
uniprot id: A0A160JCR4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS00360
gene id: 1226968:A6A40_RS00360
uniprot id: A0A168XZ14
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1226968:A6A40 RS03620
gene id: 1226968:A6A40_RS03620
uniprot id: A0A160JE73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1226968:A6A40 RS12050
gene id: 1226968:A6A40_RS12050
uniprot id: A0A160JJ25
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1226968:A6A40 RS01375
gene id: 1226968:A6A40_RS01375
uniprot id: A0A160JD92
names: Similarity
messages: Belongs to the UPF0758 family.

1226968:A6A40 RS03405
gene id: 1226968:A6A40_RS03405
uniprot id: A0A168Y208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1226968:A6A40 RS07365
gene id: 1226968:A6A40_RS07365
uniprot id: A0A160JGB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1226968:A6A40 RS13850
gene id: 1226968:A6A40_RS13850
uniprot id: A0A160JIT9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1226968:A6A40 RS14545
gene id: 1226968:A6A40_RS14545
uniprot id: A0A160JIJ4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1226968:A6A40 RS01960
gene id: 1226968:A6A40_RS01960
uniprot id: A0A160JDH0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1226968:A6A40 RS11695
gene id: 1226968:A6A40_RS11695
uniprot id: A0A161JHE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1226968:A6A40 RS10900
gene id: 1226968:A6A40_RS10900
uniprot id: A0A160JJ20
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS07965
gene id: 1226968:A6A40_RS07965
uniprot id: A0A160JFY2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1226968:A6A40 RS07140
gene id: 1226968:A6A40_RS07140
uniprot id: A0A160JG83
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1226968:A6A40 RS14215
gene id: 1226968:A6A40_RS14215
uniprot id: A0A168YC67
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1226968:A6A40 RS06680
gene id: 1226968:A6A40_RS06680
uniprot id: A0A161ITU7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1226968:A6A40 RS06810
gene id: 1226968:A6A40_RS06810
uniprot id: A0A168Y5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1226968:A6A40 RS08595
gene id: 1226968:A6A40_RS08595
uniprot id: A0A160JG82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1226968:A6A40 RS08210
gene id: 1226968:A6A40_RS08210
uniprot id: A0A168Y6L2
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS02200
gene id: 1226968:A6A40_RS02200
uniprot id: A0A160JEA9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1226968:A6A40 RS11240
gene id: 1226968:A6A40_RS11240
uniprot id: A0A168Y9C6
names: Subcellular Location Annotation
messages: Virion

1226968:A6A40 RS08775
gene id: 1226968:A6A40_RS08775
uniprot id: A0A160JGA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1226968:A6A40 RS07235
gene id: 1226968:A6A40_RS07235
uniprot id: A0A160JFN1
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1226968:A6A40 RS05415
gene id: 1226968:A6A40_RS05415
uniprot id: A0A160JFM5
names: Similarity
messages: Belongs to the MoaD family.

1226968:A6A40 RS05925
gene id: 1226968:A6A40_RS05925
uniprot id: A0A160JF34
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1226968:A6A40 RS02955
gene id: 1226968:A6A40_RS02955
uniprot id: A0A160JDW8
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1226968:A6A40 RS07880
gene id: 1226968:A6A40_RS07880
uniprot id: A0A160JFY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1226968:A6A40 RS14365
gene id: 1226968:A6A40_RS14365
uniprot id: A0A168YCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

1226968:A6A40 RS01130
gene id: 1226968:A6A40_RS01130
uniprot id: A0A160JD72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS03475
gene id: 1226968:A6A40_RS03475
uniprot id: A0A160JEV3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1226968:A6A40 RS01955
gene id: 1226968:A6A40_RS01955
uniprot id: A0A160JDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1226968:A6A40 RS11220
gene id: 1226968:A6A40_RS11220
uniprot id: A0A160JH93
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1226968:A6A40 RS02540
gene id: 1226968:A6A40_RS02540
uniprot id: A0A160JDS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1226968:A6A40 RS04990
gene id: 1226968:A6A40_RS04990
uniprot id: A0A160JES5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1226968:A6A40 RS11120
gene id: 1226968:A6A40_RS11120
uniprot id: A0A161JHD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1226968:A6A40 RS06445
gene id: 1226968:A6A40_RS06445
uniprot id: A0A160JFF6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1226968:A6A40 RS13955
gene id: 1226968:A6A40_RS13955
uniprot id: A0A160JIB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1226968:A6A40 RS08400
gene id: 1226968:A6A40_RS08400
uniprot id: A0A168Y6Q7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1226968:A6A40 RS10045
gene id: 1226968:A6A40_RS10045
uniprot id: A0A160JGS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1226968:A6A40 RS11610
gene id: 1226968:A6A40_RS11610
uniprot id: A0A160JHG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1226968:A6A40 RS05320
gene id: 1226968:A6A40_RS05320
uniprot id: A0A160JF04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1226968:A6A40 RS07395
gene id: 1226968:A6A40_RS07395
uniprot id: A0A160JFS0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1226968:A6A40 RS09320
gene id: 1226968:A6A40_RS09320
uniprot id: A0A160JGK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1226968:A6A40 RS13700
gene id: 1226968:A6A40_RS13700
uniprot id: A0A168YBK8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1226968:A6A40 RS12315
gene id: 1226968:A6A40_RS12315
uniprot id: A0A160JHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1226968:A6A40 RS04845
gene id: 1226968:A6A40_RS04845
uniprot id: A0A160JEM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS10090
gene id: 1226968:A6A40_RS10090
uniprot id: A0A160JGT3
names: Similarity
messages: Belongs to the YciI family.

1226968:A6A40 RS02680
gene id: 1226968:A6A40_RS02680
uniprot id: A0A160JEI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1226968:A6A40 RS03535
gene id: 1226968:A6A40_RS03535
uniprot id: A0A160JE99
names: Similarity
messages: Belongs to the universal stress protein A family.

1226968:A6A40 RS04635
gene id: 1226968:A6A40_RS04635
uniprot id: A0A160JEK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1226968:A6A40 RS03580
gene id: 1226968:A6A40_RS03580
uniprot id: A0A160JE44
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1226968:A6A40 RS03960
gene id: 1226968:A6A40_RS03960
uniprot id: A0A160JEB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1226968:A6A40 RS03480
gene id: 1226968:A6A40_RS03480
uniprot id: A0A160JE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS03040
gene id: 1226968:A6A40_RS03040
uniprot id: A0A160JDZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1226968:A6A40 RS13980
gene id: 1226968:A6A40_RS13980
uniprot id: A0A160JIC5
names: Similarity
messages: Belongs to the LOG family.

1226968:A6A40 RS04345
gene id: 1226968:A6A40_RS04345
uniprot id: A0A160JEH5
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS04555
gene id: 1226968:A6A40_RS04555
uniprot id: A0A160JEK4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS08350
gene id: 1226968:A6A40_RS08350
uniprot id: A0A160JG49
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1226968:A6A40 RS13145
gene id: 1226968:A6A40_RS13145
uniprot id: A0A160JI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1226968:A6A40 RS12055
gene id: 1226968:A6A40_RS12055
uniprot id: A0A160JHP0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1226968:A6A40 RS13485
gene id: 1226968:A6A40_RS13485
uniprot id: A0A160JI51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1226968:A6A40 RS05515
gene id: 1226968:A6A40_RS05515
uniprot id: A0A161JB97
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS01600
gene id: 1226968:A6A40_RS01600
uniprot id: A0A160JDD6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1226968:A6A40 RS08985
gene id: 1226968:A6A40_RS08985
uniprot id: A0A168Y774
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS07765
gene id: 1226968:A6A40_RS07765
uniprot id: A0A160JFW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1226968:A6A40 RS04065
gene id: 1226968:A6A40_RS04065
uniprot id: A0A160JEE0
names: Similarity
messages: Belongs to the YkuD family.

1226968:A6A40 RS01865
gene id: 1226968:A6A40_RS01865
uniprot id: A0A160JE59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1226968:A6A40 RS03175
gene id: 1226968:A6A40_RS03175
uniprot id: A0A160JER4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS05390
gene id: 1226968:A6A40_RS05390
uniprot id: A0A160JEX5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1226968:A6A40 RS08790
gene id: 1226968:A6A40_RS08790
uniprot id: A0A160JIX4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1226968:A6A40 RS08045
gene id: 1226968:A6A40_RS08045
uniprot id: A0A160JG34
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS07300
gene id: 1226968:A6A40_RS07300
uniprot id: A0A160JFN3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1226968:A6A40 RS02475
gene id: 1226968:A6A40_RS02475
uniprot id: A0A160JDP2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1226968:A6A40 RS08955
gene id: 1226968:A6A40_RS08955
uniprot id: A0A160JGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1226968:A6A40 RS05895
gene id: 1226968:A6A40_RS05895
uniprot id: A0A160JF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1226968:A6A40 RS00695
gene id: 1226968:A6A40_RS00695
uniprot id: A0A160JCZ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1226968:A6A40 RS07600
gene id: 1226968:A6A40_RS07600
uniprot id: A0A160JFU0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1226968:A6A40 RS05330
gene id: 1226968:A6A40_RS05330
uniprot id: A0A160JEV2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS06480
gene id: 1226968:A6A40_RS06480
uniprot id: A0A160JFC1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1226968:A6A40 RS01815
gene id: 1226968:A6A40_RS01815
uniprot id: A0A160JE50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1226968:A6A40 RS10460
gene id: 1226968:A6A40_RS10460
uniprot id: A0A168Y8P5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1226968:A6A40 RS05765
gene id: 1226968:A6A40_RS05765
uniprot id: A0A160JF12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1226968:A6A40 RS01595
gene id: 1226968:A6A40_RS01595
uniprot id: A0A160JDC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1226968:A6A40 RS08320
gene id: 1226968:A6A40_RS08320
uniprot id: A0A161ITZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1226968:A6A40 RS05510
gene id: 1226968:A6A40_RS05510
uniprot id: A0A160JEY8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1226968:A6A40 RS08625
gene id: 1226968:A6A40_RS08625
uniprot id: A0A168Y6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1226968:A6A40 RS10445
gene id: 1226968:A6A40_RS10445
uniprot id: A0A160JGY9
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1226968:A6A40 RS09890
gene id: 1226968:A6A40_RS09890
uniprot id: A0A160JGQ2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1226968:A6A40 RS14155
gene id: 1226968:A6A40_RS14155
uniprot id: A0A160JIE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1226968:A6A40 RS00855
gene id: 1226968:A6A40_RS00855
uniprot id: A0A160JDS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1226968:A6A40 RS00865
gene id: 1226968:A6A40_RS00865
uniprot id: A0A160JD74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1226968:A6A40 RS02855
gene id: 1226968:A6A40_RS02855
uniprot id: A0A160JDZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

1226968:A6A40 RS00085
gene id: 1226968:A6A40_RS00085
uniprot id: A0A160JCR9
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS10595
gene id: 1226968:A6A40_RS10595
uniprot id: A0A168YDK8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS05645
gene id: 1226968:A6A40_RS05645
uniprot id: A0A160JF50
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1226968:A6A40 RS05070
gene id: 1226968:A6A40_RS05070
uniprot id: A0A160JER3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1226968:A6A40 RS12640
gene id: 1226968:A6A40_RS12640
uniprot id: A0A160JID4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS05520
gene id: 1226968:A6A40_RS05520
uniprot id: A0A160JEY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1226968:A6A40 RS07400
gene id: 1226968:A6A40_RS07400
uniprot id: A0A161IQ22
names: Subcellular Location Annotation
messages: Periplasm

1226968:A6A40 RS12925
gene id: 1226968:A6A40_RS12925
uniprot id: A0A160JHX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1226968:A6A40 RS12420
gene id: 1226968:A6A40_RS12420
uniprot id: A0A160JHR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1226968:A6A40 RS02505
gene id: 1226968:A6A40_RS02505
uniprot id: A0A160JEG0
names: Similarity
messages: Belongs to the peptidase S11 family.

1226968:A6A40 RS03015
gene id: 1226968:A6A40_RS03015
uniprot id: A0A160JEN1
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1226968:A6A40 RS01145
gene id: 1226968:A6A40_RS01145
uniprot id: A0A160JD51
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1226968:A6A40 RS01450
gene id: 1226968:A6A40_RS01450
uniprot id: A0A160JD89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

1226968:A6A40 RS01990
gene id: 1226968:A6A40_RS01990
uniprot id: A0A160JDG7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1226968:A6A40 RS01135
gene id: 1226968:A6A40_RS01135
uniprot id: A0A168XZN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS04465
gene id: 1226968:A6A40_RS04465
uniprot id: A0A160JEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1226968:A6A40 RS12240
gene id: 1226968:A6A40_RS12240
uniprot id: A0A160JHN2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1226968:A6A40 RS12165
gene id: 1226968:A6A40_RS12165
uniprot id: A0A160JHM8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1226968:A6A40 RS06980
gene id: 1226968:A6A40_RS06980
uniprot id: A0A160JFJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1226968:A6A40 RS10075
gene id: 1226968:A6A40_RS10075
uniprot id: A0A160JGT8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS11620
gene id: 1226968:A6A40_RS11620
uniprot id: A0A160JHE7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1226968:A6A40 RS06390
gene id: 1226968:A6A40_RS06390
uniprot id: A0A161ITT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1226968:A6A40 RS10720
gene id: 1226968:A6A40_RS10720
uniprot id: A0A160JJ05
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1226968:A6A40 RS01895
gene id: 1226968:A6A40_RS01895
uniprot id: A0A160JDH1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1226968:A6A40 RS00575
gene id: 1226968:A6A40_RS00575
uniprot id: A0A160JD33
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1226968:A6A40 RS08505
gene id: 1226968:A6A40_RS08505
uniprot id: A0A160JG87
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1226968:A6A40 RS12230
gene id: 1226968:A6A40_RS12230
uniprot id: A0A160JHR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1226968:A6A40 RS04955
gene id: 1226968:A6A40_RS04955
uniprot id: A0A160JEP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1226968:A6A40 RS12835
gene id: 1226968:A6A40_RS12835
uniprot id: A0A160JI06
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1226968:A6A40 RS03805
gene id: 1226968:A6A40_RS03805
uniprot id: A0A160JE94
names: Similarity
messages: Belongs to the SBNO family.

1226968:A6A40 RS14075
gene id: 1226968:A6A40_RS14075
uniprot id: A0A160JIX8
names: Similarity
messages: Belongs to the peptidase M20A family.

1226968:A6A40 RS07585
gene id: 1226968:A6A40_RS07585
uniprot id: A0A160JFT8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1226968:A6A40 RS10355
gene id: 1226968:A6A40_RS10355
uniprot id: A0A168Y8I3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1226968:A6A40 RS04910
gene id: 1226968:A6A40_RS04910
uniprot id: A0A160JEP7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1226968:A6A40 RS12955
gene id: 1226968:A6A40_RS12955
uniprot id: A0A160JIH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1226968:A6A40 RS10215
gene id: 1226968:A6A40_RS10215
uniprot id: A0A160JGU5
names: Similarity
messages: Belongs to the leucine-binding protein family.

1226968:A6A40 RS09000
gene id: 1226968:A6A40_RS09000
uniprot id: A0A160JH06
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS08850
gene id: 1226968:A6A40_RS08850
uniprot id: A0A161JH89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1226968:A6A40 RS07090
gene id: 1226968:A6A40_RS07090
uniprot id: A0A160JG74
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1226968:A6A40 RS10025
gene id: 1226968:A6A40_RS10025
uniprot id: A0A160JIZ7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1226968:A6A40 RS02455
gene id: 1226968:A6A40_RS02455
uniprot id: A0A160JDP4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1226968:A6A40 RS10885
gene id: 1226968:A6A40_RS10885
uniprot id: A0A160JH53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1226968:A6A40 RS01835
gene id: 1226968:A6A40_RS01835
uniprot id: A0A160JDE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1226968:A6A40 RS12415
gene id: 1226968:A6A40_RS12415
uniprot id: A0A160JHR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1226968:A6A40 RS08360
gene id: 1226968:A6A40_RS08360
uniprot id: A0A160JGR5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS02165
gene id: 1226968:A6A40_RS02165
uniprot id: A0A160JIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1226968:A6A40 RS09885
gene id: 1226968:A6A40_RS09885
uniprot id: A0A160JHC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS01850
gene id: 1226968:A6A40_RS01850
uniprot id: A0A161IPP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1226968:A6A40 RS08620
gene id: 1226968:A6A40_RS08620
uniprot id: A0A160JGA9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1226968:A6A40 RS04930
gene id: 1226968:A6A40_RS04930
uniprot id: A0A160JEP4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS12670
gene id: 1226968:A6A40_RS12670
uniprot id: A0A160JHY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS07010
gene id: 1226968:A6A40_RS07010
uniprot id: A0A160JFJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS10830
gene id: 1226968:A6A40_RS10830
uniprot id: A0A161JHD2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1226968:A6A40 RS02895
gene id: 1226968:A6A40_RS02895
uniprot id: A0A160JEL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1226968:A6A40 RS14100
gene id: 1226968:A6A40_RS14100
uniprot id: A0A160JID7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1226968:A6A40 RS05620
gene id: 1226968:A6A40_RS05620
uniprot id: A0A168Y479
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1226968:A6A40 RS10800
gene id: 1226968:A6A40_RS10800
uniprot id: A0A161IQ96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

1226968:A6A40 RS09595
gene id: 1226968:A6A40_RS09595
uniprot id: A0A160JGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1226968:A6A40 RS02900
gene id: 1226968:A6A40_RS02900
uniprot id: A0A160JIQ7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS12660
gene id: 1226968:A6A40_RS12660
uniprot id: A0A160JHU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1226968:A6A40 RS05385
gene id: 1226968:A6A40_RS05385
uniprot id: A0A160JEX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1226968:A6A40 RS08930
gene id: 1226968:A6A40_RS08930
uniprot id: A0A160JGC5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1226968:A6A40 RS06960
gene id: 1226968:A6A40_RS06960
uniprot id: A0A160JFJ5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1226968:A6A40 RS09415
gene id: 1226968:A6A40_RS09415
uniprot id: A0A160JGM7
names: Similarity
messages: Belongs to the UPF0434 family.

1226968:A6A40 RS01785
gene id: 1226968:A6A40_RS01785
uniprot id: A0A160JDD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1226968:A6A40 RS08925
gene id: 1226968:A6A40_RS08925
uniprot id: A0A168Y750
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1226968:A6A40 RS01775
gene id: 1226968:A6A40_RS01775
uniprot id: A0A168Y0B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1226968:A6A40 RS05240
gene id: 1226968:A6A40_RS05240
uniprot id: A0A160JES8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1226968:A6A40 RS01155
gene id: 1226968:A6A40_RS01155
uniprot id: A0A160JDW4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1226968:A6A40 RS10495
gene id: 1226968:A6A40_RS10495
uniprot id: A0A160JGZ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1226968:A6A40 RS01580
gene id: 1226968:A6A40_RS01580
uniprot id: A0A160JDH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1226968:A6A40 RS09600
gene id: 1226968:A6A40_RS09600
uniprot id: A0A168Y7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS13580
gene id: 1226968:A6A40_RS13580
uniprot id: A0A160JI81
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS28205
gene id: 1226968:A6A40_RS28205
uniprot id: A0A2R4VWR3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1226968:A6A40 RS00005
gene id: 1226968:A6A40_RS00005
uniprot id: A0A160JJ68
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1226968:A6A40 RS12170
gene id: 1226968:A6A40_RS12170
uniprot id: A0A160JI77
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1226968:A6A40 RS13670
gene id: 1226968:A6A40_RS13670
uniprot id: A0A168YBH7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1226968:A6A40 RS13805
gene id: 1226968:A6A40_RS13805
uniprot id: A0A160JIB4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1226968:A6A40 RS08580
gene id: 1226968:A6A40_RS08580
uniprot id: A0A160JG78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1226968:A6A40 RS11265
gene id: 1226968:A6A40_RS11265
uniprot id: A0A160JH99
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1226968:A6A40 RS01225
gene id: 1226968:A6A40_RS01225
uniprot id: A0A160JD60
names: Similarity
messages: Belongs to the acylphosphatase family.

1226968:A6A40 RS09110
gene id: 1226968:A6A40_RS09110
uniprot id: A0A160JGE6
names: Similarity
messages: Belongs to the NifZ family.

1226968:A6A40 RS02045
gene id: 1226968:A6A40_RS02045
uniprot id: A0A160JDI2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1226968:A6A40 RS08195
gene id: 1226968:A6A40_RS08195
uniprot id: A0A160JG32
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1226968:A6A40 RS05475
gene id: 1226968:A6A40_RS05475
uniprot id: A0A160JEW4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1226968:A6A40 RS02480
gene id: 1226968:A6A40_RS02480
uniprot id: A0A160JDR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1226968:A6A40 RS05535
gene id: 1226968:A6A40_RS05535
uniprot id: A0A160JEX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1226968:A6A40 RS08760
gene id: 1226968:A6A40_RS08760
uniprot id: A0A160JGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1226968:A6A40 RS05690
gene id: 1226968:A6A40_RS05690
uniprot id: A0A160JF03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1226968:A6A40 RS13045
gene id: 1226968:A6A40_RS13045
uniprot id: A0A168YAY9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1226968:A6A40 RS04320
gene id: 1226968:A6A40_RS04320
uniprot id: A0A160JEG1
names: Similarity
messages: Belongs to the VgrG protein family.

1226968:A6A40 RS06765
gene id: 1226968:A6A40_RS06765
uniprot id: A0A160JFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS11370
gene id: 1226968:A6A40_RS11370
uniprot id: A0A160JHB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1226968:A6A40 RS09020
gene id: 1226968:A6A40_RS09020
uniprot id: A0A160JGE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1226968:A6A40 RS13215
gene id: 1226968:A6A40_RS13215
uniprot id: A0A160JI13
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS08245
gene id: 1226968:A6A40_RS08245
uniprot id: A0A160JG22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1226968:A6A40 RS09260
gene id: 1226968:A6A40_RS09260
uniprot id: A0A160JGI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1226968:A6A40 RS14660
gene id: 1226968:A6A40_RS14660
uniprot id: A0A160JJ60
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS08630
gene id: 1226968:A6A40_RS08630
uniprot id: A0A160JG86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1226968:A6A40 RS09310
gene id: 1226968:A6A40_RS09310
uniprot id: A0A160JGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1226968:A6A40 RS09620
gene id: 1226968:A6A40_RS09620
uniprot id: A0A168Y7X0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1226968:A6A40 RS05325
gene id: 1226968:A6A40_RS05325
uniprot id: A0A168Y3V2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1226968:A6A40 RS09435
gene id: 1226968:A6A40_RS09435
uniprot id: A0A160JGM5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1226968:A6A40 RS09935
gene id: 1226968:A6A40_RS09935
uniprot id: A0A160JGQ8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1226968:A6A40 RS05755
gene id: 1226968:A6A40_RS05755
uniprot id: A0A160JF10
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS11775
gene id: 1226968:A6A40_RS11775
uniprot id: A0A160JHH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1226968:A6A40 RS10530
gene id: 1226968:A6A40_RS10530
uniprot id: A0A160JHL1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1226968:A6A40 RS10295
gene id: 1226968:A6A40_RS10295
uniprot id: A0A160JGX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1226968:A6A40 RS10975
gene id: 1226968:A6A40_RS10975
uniprot id: A0A160JH60
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1226968:A6A40 RS32255
gene id: 1226968:A6A40_RS32255
uniprot id: A0A160JEC8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS13570
gene id: 1226968:A6A40_RS13570
uniprot id: A0A160JIP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS11655
gene id: 1226968:A6A40_RS11655
uniprot id: A0A161IQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1226968:A6A40 RS14495
gene id: 1226968:A6A40_RS14495
uniprot id: A0A160JJ69
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS08525
gene id: 1226968:A6A40_RS08525
uniprot id: A0A160JG67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1226968:A6A40 RS04505
gene id: 1226968:A6A40_RS04505
uniprot id: A0A168Y372
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1226968:A6A40 RS05395
gene id: 1226968:A6A40_RS05395
uniprot id: A0A160JIV5
names: Similarity
messages: Belongs to the YjdM family.

1226968:A6A40 RS12235
gene id: 1226968:A6A40_RS12235
uniprot id: A0A168YA96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1226968:A6A40 RS12305
gene id: 1226968:A6A40_RS12305
uniprot id: A0A161JHG4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1226968:A6A40 RS07500
gene id: 1226968:A6A40_RS07500
uniprot id: A0A160JFR8
names: Similarity
messages: Belongs to the DprA/Smf family.

1226968:A6A40 RS07670
gene id: 1226968:A6A40_RS07670
uniprot id: A0A161IQ28
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1226968:A6A40 RS09980
gene id: 1226968:A6A40_RS09980
uniprot id: A0A160JGR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1226968:A6A40 RS10210
gene id: 1226968:A6A40_RS10210
uniprot id: A0A160JHG4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS03610
gene id: 1226968:A6A40_RS03610
uniprot id: A0A161ITJ1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1226968:A6A40 RS12595
gene id: 1226968:A6A40_RS12595
uniprot id: A0A160JHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1226968:A6A40 RS07655
gene id: 1226968:A6A40_RS07655
uniprot id: A0A160JFV2
names: Similarity
messages: Belongs to the peptidase S1B family.

1226968:A6A40 RS03095
gene id: 1226968:A6A40_RS03095
uniprot id: A0A160JDY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1226968:A6A40 RS00960
gene id: 1226968:A6A40_RS00960
uniprot id: A0A160JD23
names: Similarity
messages: Belongs to the PspA/IM30 family.

1226968:A6A40 RS03575
gene id: 1226968:A6A40_RS03575
uniprot id: A0A161JB62
names: Similarity
messages: Belongs to the ros/MucR family.

1226968:A6A40 RS04710
gene id: 1226968:A6A40_RS04710
uniprot id: A0A161ITN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1226968:A6A40 RS10280
gene id: 1226968:A6A40_RS10280
uniprot id: A0A168YDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1226968:A6A40 RS02785
gene id: 1226968:A6A40_RS02785
uniprot id: A0A160JDT6
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1226968:A6A40 RS14625
gene id: 1226968:A6A40_RS14625
uniprot id: A0A160JIK2
names: Similarity
messages: Belongs to the thioredoxin family.

1226968:A6A40 RS08420
gene id: 1226968:A6A40_RS08420
uniprot id: A0A160JGS2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS14130
gene id: 1226968:A6A40_RS14130
uniprot id: A0A160JIG5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1226968:A6A40 RS11015
gene id: 1226968:A6A40_RS11015
uniprot id: A0A160JH71
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1226968:A6A40 RS14605
gene id: 1226968:A6A40_RS14605
uniprot id: A0A160JJ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1226968:A6A40 RS08585
gene id: 1226968:A6A40_RS08585
uniprot id: A0A160JG73
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS01415
gene id: 1226968:A6A40_RS01415
uniprot id: A0A160JDA0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1226968:A6A40 RS11525
gene id: 1226968:A6A40_RS11525
uniprot id: A0A160JHE1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1226968:A6A40 RS04400
gene id: 1226968:A6A40_RS04400
uniprot id: A0A161JB77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1226968:A6A40 RS13500
gene id: 1226968:A6A40_RS13500
uniprot id: A0A160JIN9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS03990
gene id: 1226968:A6A40_RS03990
uniprot id: A0A160JEG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1226968:A6A40 RS07920
gene id: 1226968:A6A40_RS07920
uniprot id: A0A160JGJ8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1226968:A6A40 RS03605
gene id: 1226968:A6A40_RS03605
uniprot id: A0A160JEA6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1226968:A6A40 RS07620
gene id: 1226968:A6A40_RS07620
uniprot id: A0A160JFT6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1226968:A6A40 RS07315
gene id: 1226968:A6A40_RS07315
uniprot id: A0A160JFP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1226968:A6A40 RS01945
gene id: 1226968:A6A40_RS01945
uniprot id: A0A160JDH5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1226968:A6A40 RS14675
gene id: 1226968:A6A40_RS14675
uniprot id: A0A168YCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS06990
gene id: 1226968:A6A40_RS06990
uniprot id: A0A160JG60
names: Similarity
messages: Belongs to the ArsC family.

1226968:A6A40 RS06190
gene id: 1226968:A6A40_RS06190
uniprot id: A0A160JF77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1226968:A6A40 RS10990
gene id: 1226968:A6A40_RS10990
uniprot id: A0A160JH62
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1226968:A6A40 RS12650
gene id: 1226968:A6A40_RS12650
uniprot id: A0A160JHW7
names: Similarity
messages: Belongs to the UPF0162 family.

1226968:A6A40 RS02155
gene id: 1226968:A6A40_RS02155
uniprot id: A0A160JDJ6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1226968:A6A40 RS05000
gene id: 1226968:A6A40_RS05000
uniprot id: A0A168Y3I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1226968:A6A40 RS01120
gene id: 1226968:A6A40_RS01120
uniprot id: A0A160JD63
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1226968:A6A40 RS02170
gene id: 1226968:A6A40_RS02170
uniprot id: A0A160JDK9
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1226968:A6A40 RS04005
gene id: 1226968:A6A40_RS04005
uniprot id: A0A160JEB1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1226968:A6A40 RS08965
gene id: 1226968:A6A40_RS08965
uniprot id: A0A168Y761
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1226968:A6A40 RS03745
gene id: 1226968:A6A40_RS03745
uniprot id: A0A160JE87
names: Similarity
messages: Belongs to the ArsC family.

1226968:A6A40 RS04475
gene id: 1226968:A6A40_RS04475
uniprot id: A0A160JEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS07710
gene id: 1226968:A6A40_RS07710
uniprot id: A0A160JFV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS11470
gene id: 1226968:A6A40_RS11470
uniprot id: A0A160JHD3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1226968:A6A40 RS13025
gene id: 1226968:A6A40_RS13025
uniprot id: A0A168YAX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1226968:A6A40 RS12365
gene id: 1226968:A6A40_RS12365
uniprot id: A0A160JHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1226968:A6A40 RS14210
gene id: 1226968:A6A40_RS14210
uniprot id: A0A160JIH5
names: Similarity
messages: Belongs to the peptidase C40 family.

1226968:A6A40 RS13385
gene id: 1226968:A6A40_RS13385
uniprot id: A0A160JIM3
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS03495
gene id: 1226968:A6A40_RS03495
uniprot id: A0A160JE43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1226968:A6A40 RS08065
gene id: 1226968:A6A40_RS08065
uniprot id: A0A160JG26
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS02770
gene id: 1226968:A6A40_RS02770
uniprot id: A0A160JDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1226968:A6A40 RS21095
gene id: 1226968:A6A40_RS21095
uniprot id: A0A2R4VTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS08590
gene id: 1226968:A6A40_RS08590
uniprot id: A0A160JGV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1226968:A6A40 RS08910
gene id: 1226968:A6A40_RS08910
uniprot id: A0A160JGC7
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS10880
gene id: 1226968:A6A40_RS10880
uniprot id: A0A161IU81
names: Similarity
messages: Belongs to the TrpF family.

1226968:A6A40 RS13985
gene id: 1226968:A6A40_RS13985
uniprot id: A0A160JID9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1226968:A6A40 RS12260
gene id: 1226968:A6A40_RS12260
uniprot id: A0A160JHT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS11520
gene id: 1226968:A6A40_RS11520
uniprot id: A0A160JHD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1226968:A6A40 RS06425
gene id: 1226968:A6A40_RS06425
uniprot id: A0A160JFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1226968:A6A40 RS07390
gene id: 1226968:A6A40_RS07390
uniprot id: A0A160JFR1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1226968:A6A40 RS03285
gene id: 1226968:A6A40_RS03285
uniprot id: A0A160JE22
names: Similarity
messages: Belongs to the threonine synthase family.

1226968:A6A40 RS05210
gene id: 1226968:A6A40_RS05210
uniprot id: A0A160JEU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1226968:A6A40 RS07480
gene id: 1226968:A6A40_RS07480
uniprot id: A0A160JGD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1226968:A6A40 RS10360
gene id: 1226968:A6A40_RS10360
uniprot id: A0A160JGX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1226968:A6A40 RS13125
gene id: 1226968:A6A40_RS13125
uniprot id: A0A160JI03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1226968:A6A40 RS03420
gene id: 1226968:A6A40_RS03420
uniprot id: A0A160JEU8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1226968:A6A40 RS25405
gene id: 1226968:A6A40_RS25405
uniprot id: A0A2R4VVB5
names: Similarity
messages: Belongs to the peptidase C56 family.

1226968:A6A40 RS04405
gene id: 1226968:A6A40_RS04405
uniprot id: A0A160JEG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1226968:A6A40 RS02405
gene id: 1226968:A6A40_RS02405
uniprot id: A0A160JDN4
names: Similarity
messages: Belongs to the SDHAF4 family.

1226968:A6A40 RS05380
gene id: 1226968:A6A40_RS05380
uniprot id: A0A160JEW0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1226968:A6A40 RS03585
gene id: 1226968:A6A40_RS03585
uniprot id: A0A160JIR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS12860
gene id: 1226968:A6A40_RS12860
uniprot id: A0A160JHW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1226968:A6A40 RS13650
gene id: 1226968:A6A40_RS13650
uniprot id: A0A160JI65
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1226968:A6A40 RS10250
gene id: 1226968:A6A40_RS10250
uniprot id: A0A160JGV5
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1226968:A6A40 RS13945
gene id: 1226968:A6A40_RS13945
uniprot id: A0A160JIE3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1226968:A6A40 RS01935
gene id: 1226968:A6A40_RS01935
uniprot id: A0A160JDG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1226968:A6A40 RS00565
gene id: 1226968:A6A40_RS00565
uniprot id: A0A160JDN5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

1226968:A6A40 RS07775
gene id: 1226968:A6A40_RS07775
uniprot id: A0A160JFY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1226968:A6A40 RS08640
gene id: 1226968:A6A40_RS08640
uniprot id: A0A160JGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1226968:A6A40 RS03720
gene id: 1226968:A6A40_RS03720
uniprot id: A0A160JEC5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1226968:A6A40 RS02240
gene id: 1226968:A6A40_RS02240
uniprot id: A0A168Y0P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

1226968:A6A40 RS12760
gene id: 1226968:A6A40_RS12760
uniprot id: A0A160JHZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS09855
gene id: 1226968:A6A40_RS09855
uniprot id: A0A160JGR1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.

1226968:A6A40 RS10715
gene id: 1226968:A6A40_RS10715
uniprot id: A0A160JH18
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS07855
gene id: 1226968:A6A40_RS07855
uniprot id: A0A160JFW5
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1226968:A6A40 RS10670
gene id: 1226968:A6A40_RS10670
uniprot id: A0A160JH47
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1226968:A6A40 RS03455
gene id: 1226968:A6A40_RS03455
uniprot id: A0A168Y242
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Membrane
messages: Periplasm

1226968:A6A40 RS03615
gene id: 1226968:A6A40_RS03615
uniprot id: A0A160JE56
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS19925
gene id: 1226968:A6A40_RS19925
uniprot id: A0A2R4VSD0
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS05480
gene id: 1226968:A6A40_RS05480
uniprot id: A0A160JFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1226968:A6A40 RS12290
gene id: 1226968:A6A40_RS12290
uniprot id: A0A160JHN8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1226968:A6A40 RS05540
gene id: 1226968:A6A40_RS05540
uniprot id: A0A160JF35
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1226968:A6A40 RS00845
gene id: 1226968:A6A40_RS00845
uniprot id: A0A160JD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS09370
gene id: 1226968:A6A40_RS09370
uniprot id: A0A160JGL9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS09275
gene id: 1226968:A6A40_RS09275
uniprot id: A0A160JGG8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1226968:A6A40 RS09015
gene id: 1226968:A6A40_RS09015
uniprot id: A0A168Y785
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1226968:A6A40 RS09835
gene id: 1226968:A6A40_RS09835
uniprot id: A0A160JGP4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1226968:A6A40 RS14400
gene id: 1226968:A6A40_RS14400
uniprot id: A0A160JJ21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1226968:A6A40 RS14520
gene id: 1226968:A6A40_RS14520
uniprot id: A0A160JJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1226968:A6A40 RS08945
gene id: 1226968:A6A40_RS08945
uniprot id: A0A160JGC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1226968:A6A40 RS09560
gene id: 1226968:A6A40_RS09560
uniprot id: A0A168Y7T8
names: Similarity
messages: Belongs to the peptidase S41A family.

1226968:A6A40 RS14175
gene id: 1226968:A6A40_RS14175
uniprot id: A0A168YC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1226968:A6A40 RS07695
gene id: 1226968:A6A40_RS07695
uniprot id: A0A160JFY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1226968:A6A40 RS02115
gene id: 1226968:A6A40_RS02115
uniprot id: A0A161IPQ4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1226968:A6A40 RS03255
gene id: 1226968:A6A40_RS03255
uniprot id: A0A160JE65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1226968:A6A40 RS05410
gene id: 1226968:A6A40_RS05410
uniprot id: A0A160JEV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1226968:A6A40 RS06285
gene id: 1226968:A6A40_RS06285
uniprot id: A0A168Y4X0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS02875
gene id: 1226968:A6A40_RS02875
uniprot id: A0A160JDW6
names: Similarity
messages: Belongs to the NifX/NifY family.

1226968:A6A40 RS05495
gene id: 1226968:A6A40_RS05495
uniprot id: A0A161JH16
names: Similarity
messages: Belongs to the Gfa family.

1226968:A6A40 RS05435
gene id: 1226968:A6A40_RS05435
uniprot id: A0A160JEW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1226968:A6A40 RS07650
gene id: 1226968:A6A40_RS07650
uniprot id: A0A160JFU8
names: Similarity
messages: Belongs to the RutC family.

1226968:A6A40 RS04795
gene id: 1226968:A6A40_RS04795
uniprot id: A0A160JEL6
names: Similarity
messages: Belongs to the virb1 family.

1226968:A6A40 RS00335
gene id: 1226968:A6A40_RS00335
uniprot id: A0A160JCU4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS01025
gene id: 1226968:A6A40_RS01025
uniprot id: A0A161JB26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1226968:A6A40 RS01725
gene id: 1226968:A6A40_RS01725
uniprot id: A0A160JDF1
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS00590
gene id: 1226968:A6A40_RS00590
uniprot id: A0A160JCX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS10020
gene id: 1226968:A6A40_RS10020
uniprot id: A0A160JGT4
names: Function
names: Similarity
messages: Belongs to the CowN family.
messages: Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.

1226968:A6A40 RS05055
gene id: 1226968:A6A40_RS05055
uniprot id: A0A160JER0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1226968:A6A40 RS12180
gene id: 1226968:A6A40_RS12180
uniprot id: A0A160JHQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1226968:A6A40 RS19320
gene id: 1226968:A6A40_RS19320
uniprot id: A0A2R4VS07
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1226968:A6A40 RS04560
gene id: 1226968:A6A40_RS04560
uniprot id: A0A168Y392
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1226968:A6A40 RS03290
gene id: 1226968:A6A40_RS03290
uniprot id: A0A161JB57
names: Similarity
messages: Belongs to the peptidase M16 family.

1226968:A6A40 RS11350
gene id: 1226968:A6A40_RS11350
uniprot id: A0A160JHB5
names: Similarity
messages: Belongs to the universal stress protein A family.

1226968:A6A40 RS07635
gene id: 1226968:A6A40_RS07635
uniprot id: A0A160JFU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1226968:A6A40 RS01615
gene id: 1226968:A6A40_RS01615
uniprot id: A0A160JDC7
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1226968:A6A40 RS04535
gene id: 1226968:A6A40_RS04535
uniprot id: A0A160JIS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1226968:A6A40 RS02755
gene id: 1226968:A6A40_RS02755
uniprot id: A0A161ITG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1226968:A6A40 RS12250
gene id: 1226968:A6A40_RS12250
uniprot id: A0A160JHP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1226968:A6A40 RS04670
gene id: 1226968:A6A40_RS04670
uniprot id: A0A161JB83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS12320
gene id: 1226968:A6A40_RS12320
uniprot id: A0A160JHT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1226968:A6A40 RS05185
gene id: 1226968:A6A40_RS05185
uniprot id: A0A160JES3
names: Similarity
messages: Belongs to the universal stress protein A family.

1226968:A6A40 RS06240
gene id: 1226968:A6A40_RS06240
uniprot id: A0A160JF97
names: Similarity
messages: Belongs to the peptidase U62 family.

1226968:A6A40 RS12115
gene id: 1226968:A6A40_RS12115
uniprot id: A0A168Y9Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS12430
gene id: 1226968:A6A40_RS12430
uniprot id: A0A168YAD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1226968:A6A40 RS08405
gene id: 1226968:A6A40_RS08405
uniprot id: A0A160JG57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1226968:A6A40 RS13530
gene id: 1226968:A6A40_RS13530
uniprot id: A0A160JI52
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1226968:A6A40 RS09315
gene id: 1226968:A6A40_RS09315
uniprot id: A0A160JGJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1226968:A6A40 RS06450
gene id: 1226968:A6A40_RS06450
uniprot id: A0A168Y507
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1226968:A6A40 RS05655
gene id: 1226968:A6A40_RS05655
uniprot id: A0A160JF00
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1226968:A6A40 RS08310
gene id: 1226968:A6A40_RS08310
uniprot id: A0A160JG45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS12920
gene id: 1226968:A6A40_RS12920
uniprot id: A0A161JHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1226968:A6A40 RS11175
gene id: 1226968:A6A40_RS11175
uniprot id: A0A161IU88
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS02395
gene id: 1226968:A6A40_RS02395
uniprot id: A0A160JDM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1226968:A6A40 RS08265
gene id: 1226968:A6A40_RS08265
uniprot id: A0A160JG65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1226968:A6A40 RS12345
gene id: 1226968:A6A40_RS12345
uniprot id: A0A160JHP4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS12285
gene id: 1226968:A6A40_RS12285
uniprot id: A0A160JI91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1226968:A6A40 RS12065
gene id: 1226968:A6A40_RS12065
uniprot id: A0A160JHK8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1226968:A6A40 RS11475
gene id: 1226968:A6A40_RS11475
uniprot id: A0A160JHH3
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1226968:A6A40 RS22820
gene id: 1226968:A6A40_RS22820
uniprot id: A0A2R4VTY7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1226968:A6A40 RS07000
gene id: 1226968:A6A40_RS07000
uniprot id: A0A160JFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1226968:A6A40 RS03400
gene id: 1226968:A6A40_RS03400
uniprot id: A0A160JE39
names: Similarity
messages: Belongs to the CapA family.

1226968:A6A40 RS24870
gene id: 1226968:A6A40_RS24870
uniprot id: A0A2R4VWB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1226968:A6A40 RS10995
gene id: 1226968:A6A40_RS10995
uniprot id: A0A160JH97
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1226968:A6A40 RS02285
gene id: 1226968:A6A40_RS02285
uniprot id: A0A160JDM9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1226968:A6A40 RS01930
gene id: 1226968:A6A40_RS01930
uniprot id: A0A161ITE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1226968:A6A40 RS05920
gene id: 1226968:A6A40_RS05920
uniprot id: A0A160JF39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1226968:A6A40 RS11875
gene id: 1226968:A6A40_RS11875
uniprot id: A0A160JHL9
names: Similarity
messages: Belongs to the BolA/IbaG family.

1226968:A6A40 RS05555
gene id: 1226968:A6A40_RS05555
uniprot id: A0A160JEZ9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS06460
gene id: 1226968:A6A40_RS06460
uniprot id: A0A160JFB1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1226968:A6A40 RS04645
gene id: 1226968:A6A40_RS04645
uniprot id: A0A160JER1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1226968:A6A40 RS06770
gene id: 1226968:A6A40_RS06770
uniprot id: A0A160JFF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS13285
gene id: 1226968:A6A40_RS13285
uniprot id: A0A161IUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1226968:A6A40 RS10510
gene id: 1226968:A6A40_RS10510
uniprot id: A0A160JH32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1226968:A6A40 RS02805
gene id: 1226968:A6A40_RS02805
uniprot id: A0A168Y1A4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS01900
gene id: 1226968:A6A40_RS01900
uniprot id: A0A161JB38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1226968:A6A40 RS08795
gene id: 1226968:A6A40_RS08795
uniprot id: A0A168Y737
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1226968:A6A40 RS03190
gene id: 1226968:A6A40_RS03190
uniprot id: A0A168Y1V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1226968:A6A40 RS00745
gene id: 1226968:A6A40_RS00745
uniprot id: A0A160JD04
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS04100
gene id: 1226968:A6A40_RS04100
uniprot id: A0A160JEB4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1226968:A6A40 RS03140
gene id: 1226968:A6A40_RS03140
uniprot id: A0A168Y1S8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1226968:A6A40 RS08120
gene id: 1226968:A6A40_RS08120
uniprot id: A0A168Y6H2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1226968:A6A40 RS12405
gene id: 1226968:A6A40_RS12405
uniprot id: A0A160JHT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1226968:A6A40 RS13790
gene id: 1226968:A6A40_RS13790
uniprot id: A0A160JIB5
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1226968:A6A40 RS04585
gene id: 1226968:A6A40_RS04585
uniprot id: A0A160JEQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1226968:A6A40 RS00430
gene id: 1226968:A6A40_RS00430
uniprot id: A0A160JCW3
names: Similarity
messages: Belongs to the asparaginase 1 family.

1226968:A6A40 RS00860
gene id: 1226968:A6A40_RS00860
uniprot id: A0A160JD31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1226968:A6A40 RS03660
gene id: 1226968:A6A40_RS03660
uniprot id: A0A168Y280
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1226968:A6A40 RS10400
gene id: 1226968:A6A40_RS10400
uniprot id: A0A160JH19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1226968:A6A40 RS13390
gene id: 1226968:A6A40_RS13390
uniprot id: A0A160JI33
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS05545
gene id: 1226968:A6A40_RS05545
uniprot id: A0A161ITQ6
names: Similarity
messages: Belongs to the ros/MucR family.

1226968:A6A40 RS14070
gene id: 1226968:A6A40_RS14070
uniprot id: A0A160JIF8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1226968:A6A40 RS06335
gene id: 1226968:A6A40_RS06335
uniprot id: A0A161JH38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1226968:A6A40 RS25295
gene id: 1226968:A6A40_RS25295
uniprot id: A0A2R4VVB7
names: Similarity
messages: Belongs to the UPF0335 family.

1226968:A6A40 RS14705
gene id: 1226968:A6A40_RS14705
uniprot id: A0A161IQJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1226968:A6A40 RS06800
gene id: 1226968:A6A40_RS06800
uniprot id: A0A160JFH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1226968:A6A40 RS01910
gene id: 1226968:A6A40_RS01910
uniprot id: A0A160JDG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1226968:A6A40 RS12090
gene id: 1226968:A6A40_RS12090
uniprot id: A0A160JHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1226968:A6A40 RS05040
gene id: 1226968:A6A40_RS05040
uniprot id: A0A160JET3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1226968:A6A40 RS14185
gene id: 1226968:A6A40_RS14185
uniprot id: A0A160JIE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1226968:A6A40 RS06080
gene id: 1226968:A6A40_RS06080
uniprot id: A0A160JF64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS08135
gene id: 1226968:A6A40_RS08135
uniprot id: A0A160JGN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS09850
gene id: 1226968:A6A40_RS09850
uniprot id: A0A160JGQ4
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.

1226968:A6A40 RS13155
gene id: 1226968:A6A40_RS13155
uniprot id: A0A168YB31
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS12840
gene id: 1226968:A6A40_RS12840
uniprot id: A0A168YAP9
names: Similarity
messages: Belongs to the MotB family.

1226968:A6A40 RS02820
gene id: 1226968:A6A40_RS02820
uniprot id: A0A160JDW0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1226968:A6A40 RS03520
gene id: 1226968:A6A40_RS03520
uniprot id: A0A160JE38
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS17855
gene id: 1226968:A6A40_RS17855
uniprot id: A0A2R4VR87
names: Subcellular Location Annotation
messages: Cytoplasm

1226968:A6A40 RS09360
gene id: 1226968:A6A40_RS09360
uniprot id: A0A160JGJ4
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS05350
gene id: 1226968:A6A40_RS05350
uniprot id: A0A160JEV5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1226968:A6A40 RS01940
gene id: 1226968:A6A40_RS01940
uniprot id: A0A160JDI0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1226968:A6A40 RS24445
gene id: 1226968:A6A40_RS24445
uniprot id: A0A2R4VUX2
names: Subcellular Location Annotation
messages: Cytoplasm

1226968:A6A40 RS08750
gene id: 1226968:A6A40_RS08750
uniprot id: A0A160JGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1226968:A6A40 RS13255
gene id: 1226968:A6A40_RS13255
uniprot id: A0A160JJ83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1226968:A6A40 RS07915
gene id: 1226968:A6A40_RS07915
uniprot id: A0A2R4VPK2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS08610
gene id: 1226968:A6A40_RS08610
uniprot id: A0A160JG91
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1226968:A6A40 RS19325
gene id: 1226968:A6A40_RS19325
uniprot id: A0A2R4VS13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1226968:A6A40 RS03500
gene id: 1226968:A6A40_RS03500
uniprot id: A0A160JE58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1226968:A6A40 RS12855
gene id: 1226968:A6A40_RS12855
uniprot id: A0A160JIF7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1226968:A6A40 RS11320
gene id: 1226968:A6A40_RS11320
uniprot id: A0A160JHA9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS01950
gene id: 1226968:A6A40_RS01950
uniprot id: A0A168Y0F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1226968:A6A40 RS12035
gene id: 1226968:A6A40_RS12035
uniprot id: A0A160JHL4
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1226968:A6A40 RS04610
gene id: 1226968:A6A40_RS04610
uniprot id: A0A161IPV7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1226968:A6A40 RS07180
gene id: 1226968:A6A40_RS07180
uniprot id: A0A160JFM4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1226968:A6A40 RS07295
gene id: 1226968:A6A40_RS07295
uniprot id: A0A160JFN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1226968:A6A40 RS12720
gene id: 1226968:A6A40_RS12720
uniprot id: A0A160JJ41
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS08470
gene id: 1226968:A6A40_RS08470
uniprot id: A0A160JG54
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS02050
gene id: 1226968:A6A40_RS02050
uniprot id: A0A160JDJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS10085
gene id: 1226968:A6A40_RS10085
uniprot id: A0A168Y886
names: Subcellular Location Annotation
messages: Nucleus

1226968:A6A40 RS13665
gene id: 1226968:A6A40_RS13665
uniprot id: A0A160JIA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS04565
gene id: 1226968:A6A40_RS04565
uniprot id: A0A160JEI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1226968:A6A40 RS10440
gene id: 1226968:A6A40_RS10440
uniprot id: A0A168Y8L5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1226968:A6A40 RS09540
gene id: 1226968:A6A40_RS09540
uniprot id: A0A160JGL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1226968:A6A40 RS06430
gene id: 1226968:A6A40_RS06430
uniprot id: A0A160JFA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1226968:A6A40 RS00705
gene id: 1226968:A6A40_RS00705
uniprot id: A0A160JD02
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1226968:A6A40 RS07380
gene id: 1226968:A6A40_RS07380
uniprot id: A0A168Y5W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1226968:A6A40 RS06055
gene id: 1226968:A6A40_RS06055
uniprot id: A0A161JH34
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1226968:A6A40 RS14595
gene id: 1226968:A6A40_RS14595
uniprot id: A0A160JIJ1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1226968:A6A40 RS04185
gene id: 1226968:A6A40_RS04185
uniprot id: A0A160JED3
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS09675
gene id: 1226968:A6A40_RS09675
uniprot id: A0A160JGN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1226968:A6A40 RS02765
gene id: 1226968:A6A40_RS02765
uniprot id: A0A160JDU9
names: Similarity
messages: Belongs to the SCO1/2 family.

1226968:A6A40 RS11435
gene id: 1226968:A6A40_RS11435
uniprot id: A0A160JHC4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1226968:A6A40 RS04975
gene id: 1226968:A6A40_RS04975
uniprot id: A0A160JEV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1226968:A6A40 RS08140
gene id: 1226968:A6A40_RS08140
uniprot id: A0A160JG25
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS01175
gene id: 1226968:A6A40_RS01175
uniprot id: A0A160JD52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1226968:A6A40 RS14055
gene id: 1226968:A6A40_RS14055
uniprot id: A0A160JIG0
names: Similarity
messages: Belongs to the GST superfamily.

1226968:A6A40 RS13060
gene id: 1226968:A6A40_RS13060
uniprot id: A0A160JHZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1226968:A6A40 RS05710
gene id: 1226968:A6A40_RS05710
uniprot id: A0A168Y4C1
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1226968:A6A40 RS04600
gene id: 1226968:A6A40_RS04600
uniprot id: A0A160JEL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1226968:A6A40 RS03135
gene id: 1226968:A6A40_RS03135
uniprot id: A0A160JE48
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1226968:A6A40 RS00545
gene id: 1226968:A6A40_RS00545
uniprot id: A0A160JCZ0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1226968:A6A40 RS05370
gene id: 1226968:A6A40_RS05370
uniprot id: A0A160JF11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1226968:A6A40 RS02915
gene id: 1226968:A6A40_RS02915
uniprot id: A0A168Y1J7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-104 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1226968:A6A40 RS09990
gene id: 1226968:A6A40_RS09990
uniprot id: A0A160JJK3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1226968:A6A40 RS10455
gene id: 1226968:A6A40_RS10455
uniprot id: A0A160JH27
names: Subcellular Location Annotation
messages: Cytoplasm

1226968:A6A40 RS06935
gene id: 1226968:A6A40_RS06935
uniprot id: A0A160JG52
names: Similarity
messages: Belongs to the virb1 family.

1226968:A6A40 RS06780
gene id: 1226968:A6A40_RS06780
uniprot id: A0A160JFG1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1226968:A6A40 RS06330
gene id: 1226968:A6A40_RS06330
uniprot id: A0A160JFE3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1226968:A6A40 RS08555
gene id: 1226968:A6A40_RS08555
uniprot id: A0A160JG79
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1226968:A6A40 RS02760
gene id: 1226968:A6A40_RS02760
uniprot id: A0A160JDT4
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

1226968:A6A40 RS00625
gene id: 1226968:A6A40_RS00625
uniprot id: A0A160JIM1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1226968:A6A40 RS01535
gene id: 1226968:A6A40_RS01535
uniprot id: A0A168Y039
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1226968:A6A40 RS09875
gene id: 1226968:A6A40_RS09875
uniprot id: A0A160JGQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1226968:A6A40 RS02635
gene id: 1226968:A6A40_RS02635
uniprot id: A0A160JDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1226968:A6A40 RS08615
gene id: 1226968:A6A40_RS08615
uniprot id: A0A160JG92
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1226968:A6A40 RS07165
gene id: 1226968:A6A40_RS07165
uniprot id: A0A160JFM7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1226968:A6A40 RS06170
gene id: 1226968:A6A40_RS06170
uniprot id: A0A160JF84
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1226968:A6A40 RS12225
gene id: 1226968:A6A40_RS12225
uniprot id: A0A160JHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1226968:A6A40 RS12030
gene id: 1226968:A6A40_RS12030
uniprot id: A0A160JHK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1226968:A6A40 RS04970
gene id: 1226968:A6A40_RS04970
uniprot id: A0A160JEQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1226968:A6A40 RS13575
gene id: 1226968:A6A40_RS13575
uniprot id: A0A160JI56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1226968:A6A40 RS00325
gene id: 1226968:A6A40_RS00325
uniprot id: A0A160JCV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1226968:A6A40 RS01545
gene id: 1226968:A6A40_RS01545
uniprot id: A0A160JDB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1226968:A6A40 RS13760
gene id: 1226968:A6A40_RS13760
uniprot id: A0A168YBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1226968:A6A40 RS03530
gene id: 1226968:A6A40_RS03530
uniprot id: A0A160JE45
names: Similarity
messages: Belongs to the HypD family.

1226968:A6A40 RS01880
gene id: 1226968:A6A40_RS01880
uniprot id: A0A161JGT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1226968:A6A40 RS21665
gene id: 1226968:A6A40_RS21665
uniprot id: A0A2R4VT64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1226968:A6A40 RS11810
gene id: 1226968:A6A40_RS11810
uniprot id: A0A160JHH0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1226968:A6A40 RS06265
gene id: 1226968:A6A40_RS06265
uniprot id: A0A160JFW4
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1226968:A6A40 RS12880
gene id: 1226968:A6A40_RS12880
uniprot id: A0A160JHX6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1226968:A6A40 RS00615
gene id: 1226968:A6A40_RS00615
uniprot id: A0A160JCY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.

1226968:A6A40 RS12565
gene id: 1226968:A6A40_RS12565
uniprot id: A0A161IQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS00805
gene id: 1226968:A6A40_RS00805
uniprot id: A0A160JDR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1226968:A6A40 RS08185
gene id: 1226968:A6A40_RS08185
uniprot id: A0A160JG14
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1226968:A6A40 RS07385
gene id: 1226968:A6A40_RS07385
uniprot id: A0A160JFQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1226968:A6A40 RS10285
gene id: 1226968:A6A40_RS10285
uniprot id: A0A160JGW2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS07570
gene id: 1226968:A6A40_RS07570
uniprot id: A0A160JFS7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS09965
gene id: 1226968:A6A40_RS09965
uniprot id: A0A160JGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1226968:A6A40 RS08200
gene id: 1226968:A6A40_RS08200
uniprot id: A0A160JG55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS01590
gene id: 1226968:A6A40_RS01590
uniprot id: A0A160JDB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1226968:A6A40 RS12245
gene id: 1226968:A6A40_RS12245
uniprot id: A0A160JJ31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS01905
gene id: 1226968:A6A40_RS01905
uniprot id: A0A160JDE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1226968:A6A40 RS13245
gene id: 1226968:A6A40_RS13245
uniprot id: A0A160JI25
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1226968:A6A40 RS06270
gene id: 1226968:A6A40_RS06270
uniprot id: A0A160JF86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1226968:A6A40 RS02590
gene id: 1226968:A6A40_RS02590
uniprot id: A0A160JDQ9
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

1226968:A6A40 RS01490
gene id: 1226968:A6A40_RS01490
uniprot id: A0A160JDA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1226968:A6A40 RS01395
gene id: 1226968:A6A40_RS01395
uniprot id: A0A160JD96
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1226968:A6A40 RS10010
gene id: 1226968:A6A40_RS10010
uniprot id: A0A161JHB1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1226968:A6A40 RS03280
gene id: 1226968:A6A40_RS03280
uniprot id: A0A160JE26
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1226968:A6A40 RS02615
gene id: 1226968:A6A40_RS02615
uniprot id: A0A160JDR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1226968:A6A40 RS04775
gene id: 1226968:A6A40_RS04775
uniprot id: A0A160JJD0
names: Subcellular Location Annotation
messages: Membrane

1226968:A6A40 RS00900
gene id: 1226968:A6A40_RS00900
uniprot id: A0A160JD19
names: Similarity
messages: Belongs to the SfsA family.

1226968:A6A40 RS09915
gene id: 1226968:A6A40_RS09915
uniprot id: A0A160JGR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1226968:A6A40 RS04160
gene id: 1226968:A6A40_RS04160
uniprot id: A0A160JEC2
names: Similarity
messages: Belongs to the UPF0047 family.

1226968:A6A40 RS12705
gene id: 1226968:A6A40_RS12705
uniprot id: A0A160JHX2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1226968:A6A40 RS05810
gene id: 1226968:A6A40_RS05810
uniprot id: A0A160JF18
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1226968:A6A40 RS12095
gene id: 1226968:A6A40_RS12095
uniprot id: A0A160JI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1226968:A6A40 RS02275
gene id: 1226968:A6A40_RS02275
uniprot id: A0A160JDL4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1226968:A6A40 RS04545
gene id: 1226968:A6A40_RS04545
uniprot id: A0A160JEI9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1226968:A6A40 RS11785
gene id: 1226968:A6A40_RS11785
uniprot id: A0A168Y9Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1226968:A6A40 RS10435
gene id: 1226968:A6A40_RS10435
uniprot id: A0A160JH17
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.