1216932:CM240 RS10650
gene id: 1216932:CM240_RS10650
uniprot id: W6S4N4
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1216932:CM240 RS04980
gene id: 1216932:CM240_RS04980
uniprot id: W6RU81
names: Similarity
messages: Belongs to the transpeptidase family.

1216932:CM240 RS11205
gene id: 1216932:CM240_RS11205
uniprot id: W6RY96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1216932:CM240 RS08360
gene id: 1216932:CM240_RS08360
uniprot id: W6SGL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1216932:CM240 RS05235
gene id: 1216932:CM240_RS05235
uniprot id: W6RX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1216932:CM240 RS13105
gene id: 1216932:CM240_RS13105
uniprot id: W6RYQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1216932:CM240 RS07660
gene id: 1216932:CM240_RS07660
uniprot id: W6S324
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1216932:CM240 RS14135
gene id: 1216932:CM240_RS14135
uniprot id: W6S6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS05640
gene id: 1216932:CM240_RS05640
uniprot id: W6SF23
names: Similarity
messages: Belongs to the WXG100 family.

1216932:CM240 RS11825
gene id: 1216932:CM240_RS11825
uniprot id: W6SIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1216932:CM240 RS04480
gene id: 1216932:CM240_RS04480
uniprot id: W6RTZ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS08910
gene id: 1216932:CM240_RS08910
uniprot id: W6RWB2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1216932:CM240 RS12885
gene id: 1216932:CM240_RS12885
uniprot id: W6S5V7
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1216932:CM240 RS11965
gene id: 1216932:CM240_RS11965
uniprot id: W6RYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS15135
gene id: 1216932:CM240_RS15135
uniprot id: W6RZU9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1216932:CM240 RS06025
gene id: 1216932:CM240_RS06025
uniprot id: W6RVP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS09910
gene id: 1216932:CM240_RS09910
uniprot id: W6S495
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS00835
gene id: 1216932:CM240_RS00835
uniprot id: W6SCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS08505
gene id: 1216932:CM240_RS08505
uniprot id: W6RZ36
names: Similarity
messages: Belongs to the DprA/Smf family.

1216932:CM240 RS10350
gene id: 1216932:CM240_RS10350
uniprot id: W6RXR2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1216932:CM240 RS12845
gene id: 1216932:CM240_RS12845
uniprot id: W6S1H1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1216932:CM240 RS10170
gene id: 1216932:CM240_RS10170
uniprot id: W6S028
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1216932:CM240 RS12415
gene id: 1216932:CM240_RS12415
uniprot id: W6RY99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1216932:CM240 RS00980
gene id: 1216932:CM240_RS00980
uniprot id: W6RS07
names: Similarity
messages: Belongs to the thioredoxin family.

1216932:CM240 RS13550
gene id: 1216932:CM240_RS13550
uniprot id: W6RYY3
names: Similarity
messages: Belongs to the manganese catalase family.

1216932:CM240 RS08390
gene id: 1216932:CM240_RS08390
uniprot id: W6RVY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1216932:CM240 RS07330
gene id: 1216932:CM240_RS07330
uniprot id: W6S2W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1216932:CM240 RS12300
gene id: 1216932:CM240_RS12300
uniprot id: W6SIX7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS07260
gene id: 1216932:CM240_RS07260
uniprot id: W6RW62
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1216932:CM240 RS07465
gene id: 1216932:CM240_RS07465
uniprot id: W6RYG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1216932:CM240 RS00010
gene id: 1216932:CM240_RS00010
uniprot id: W6SC48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1216932:CM240 RS09465
gene id: 1216932:CM240_RS09465
uniprot id: W6RXD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1216932:CM240 RS05900
gene id: 1216932:CM240_RS05900
uniprot id: W6S221
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1216932:CM240 RS07150
gene id: 1216932:CM240_RS07150
uniprot id: W6RV98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1216932:CM240 RS07555
gene id: 1216932:CM240_RS07555
uniprot id: W6RVG9
names: Similarity
messages: Belongs to the aldose epimerase family.

1216932:CM240 RS11570
gene id: 1216932:CM240_RS11570
uniprot id: W6RYF6
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11940
gene id: 1216932:CM240_RS11940
uniprot id: W6RYM1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1216932:CM240 RS03755
gene id: 1216932:CM240_RS03755
uniprot id: W6RWC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1216932:CM240 RS12145
gene id: 1216932:CM240_RS12145
uniprot id: W6S147
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1216932:CM240 RS10060
gene id: 1216932:CM240_RS10060
uniprot id: W6S4C3
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

1216932:CM240 RS14910
gene id: 1216932:CM240_RS14910
uniprot id: W6S081
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS01190
gene id: 1216932:CM240_RS01190
uniprot id: W6RT41
names: Subcellular Location Annotation
messages: cell wall

1216932:CM240 RS04325
gene id: 1216932:CM240_RS04325
uniprot id: W6RWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1216932:CM240 RS12480
gene id: 1216932:CM240_RS12480
uniprot id: W6SIZ7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS04075
gene id: 1216932:CM240_RS04075
uniprot id: W6RUL7
names: Similarity
messages: Belongs to the peptidase U62 family.

1216932:CM240 RS15685
gene id: 1216932:CM240_RS15685
uniprot id: W6S066
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1216932:CM240 RS02665
gene id: 1216932:CM240_RS02665
uniprot id: W6S0A6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1216932:CM240 RS09610
gene id: 1216932:CM240_RS09610
uniprot id: W6S445
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1216932:CM240 RS14575
gene id: 1216932:CM240_RS14575
uniprot id: W6S6Q7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS07870
gene id: 1216932:CM240_RS07870
uniprot id: W6RVM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1216932:CM240 RS11335
gene id: 1216932:CM240_RS11335
uniprot id: W6S0R6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1216932:CM240 RS07255
gene id: 1216932:CM240_RS07255
uniprot id: W6S2U2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1216932:CM240 RS12380
gene id: 1216932:CM240_RS12380
uniprot id: W6S185
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS10500
gene id: 1216932:CM240_RS10500
uniprot id: W6S4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS05415
gene id: 1216932:CM240_RS05415
uniprot id: W6SEY8
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11700
gene id: 1216932:CM240_RS11700
uniprot id: W6SIL8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1216932:CM240 RS08395
gene id: 1216932:CM240_RS08395
uniprot id: W6S3F6
names: Similarity
messages: Belongs to the ribF family.

1216932:CM240 RS16440
gene id: 1216932:CM240_RS16440
uniprot id: W6S7T4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1216932:CM240 RS13370
gene id: 1216932:CM240_RS13370
uniprot id: W6SJE6
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS06380
gene id: 1216932:CM240_RS06380
uniprot id: W6RVU4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS11350
gene id: 1216932:CM240_RS11350
uniprot id: W6S539
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS14045
gene id: 1216932:CM240_RS14045
uniprot id: W6RZS5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1216932:CM240 RS13225
gene id: 1216932:CM240_RS13225
uniprot id: W6RZ84
names: Similarity
messages: Belongs to the peptidase S16 family.

1216932:CM240 RS07910
gene id: 1216932:CM240_RS07910
uniprot id: W6RYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1216932:CM240 RS10715
gene id: 1216932:CM240_RS10715
uniprot id: W6RXC8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS12340
gene id: 1216932:CM240_RS12340
uniprot id: W6S5K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1216932:CM240 RS13425
gene id: 1216932:CM240_RS13425
uniprot id: W6RYV4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1216932:CM240 RS09875
gene id: 1216932:CM240_RS09875
uniprot id: W6SHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

1216932:CM240 RS05340
gene id: 1216932:CM240_RS05340
uniprot id: W6SEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1216932:CM240 RS11725
gene id: 1216932:CM240_RS11725
uniprot id: W6SIM3
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS13250
gene id: 1216932:CM240_RS13250
uniprot id: W6RZ90
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1216932:CM240 RS07840
gene id: 1216932:CM240_RS07840
uniprot id: W6SGA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1216932:CM240 RS10095
gene id: 1216932:CM240_RS10095
uniprot id: W6S012
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1216932:CM240 RS15705
gene id: 1216932:CM240_RS15705
uniprot id: W6SKC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: Homotrimer.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

1216932:CM240 RS06320
gene id: 1216932:CM240_RS06320
uniprot id: W6S2C8
names: Similarity
messages: Belongs to the peptidase C56 family.

1216932:CM240 RS12040
gene id: 1216932:CM240_RS12040
uniprot id: W6RYN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1216932:CM240 RS03890
gene id: 1216932:CM240_RS03890
uniprot id: W6RTM7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS08095
gene id: 1216932:CM240_RS08095
uniprot id: W6S398
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1216932:CM240 RS10475
gene id: 1216932:CM240_RS10475
uniprot id: W6S4K2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1216932:CM240 RS02890
gene id: 1216932:CM240_RS02890
uniprot id: W6S0E4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1216932:CM240 RS03595
gene id: 1216932:CM240_RS03595
uniprot id: W6RTH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1216932:CM240 RS16145
gene id: 1216932:CM240_RS16145
uniprot id: W6S0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1216932:CM240 RS13980
gene id: 1216932:CM240_RS13980
uniprot id: W6RZR3
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1216932:CM240 RS16960
gene id: 1216932:CM240_RS16960
uniprot id: W6S1V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1216932:CM240 RS08130
gene id: 1216932:CM240_RS08130
uniprot id: W6RYV6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1216932:CM240 RS08415
gene id: 1216932:CM240_RS08415
uniprot id: W6RVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1216932:CM240 RS13870
gene id: 1216932:CM240_RS13870
uniprot id: W6RZ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1216932:CM240 RS09695
gene id: 1216932:CM240_RS09695
uniprot id: W6RZS6
names: Similarity
messages: Belongs to the UPF0473 family.

1216932:CM240 RS10690
gene id: 1216932:CM240_RS10690
uniprot id: W6SHW4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1216932:CM240 RS18105
gene id: 1216932:CM240_RS18105
uniprot id: W6S136
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1216932:CM240 RS09955
gene id: 1216932:CM240_RS09955
uniprot id: W6RWW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1216932:CM240 RS05700
gene id: 1216932:CM240_RS05700
uniprot id: W6S1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1216932:CM240 RS12400
gene id: 1216932:CM240_RS12400
uniprot id: W6RYU2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1216932:CM240 RS04460
gene id: 1216932:CM240_RS04460
uniprot id: W6RTY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1216932:CM240 RS13210
gene id: 1216932:CM240_RS13210
uniprot id: W6SJC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1216932:CM240 RS01300
gene id: 1216932:CM240_RS01300
uniprot id: W6RS94
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1216932:CM240 RS12525
gene id: 1216932:CM240_RS12525
uniprot id: W6S1A8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1216932:CM240 RS04445
gene id: 1216932:CM240_RS04445
uniprot id: W6RUR5
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12050
gene id: 1216932:CM240_RS12050
uniprot id: W6SIT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1216932:CM240 RS13095
gene id: 1216932:CM240_RS13095
uniprot id: W6S1L6
names: Similarity
messages: Belongs to the fabD family.

1216932:CM240 RS15845
gene id: 1216932:CM240_RS15845
uniprot id: W6S0P8
names: Similarity
messages: Belongs to the DtxR/MntR family.

1216932:CM240 RS16485
gene id: 1216932:CM240_RS16485
uniprot id: W6S7T9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS06585
gene id: 1216932:CM240_RS06585
uniprot id: W6S2G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1216932:CM240 RS02070
gene id: 1216932:CM240_RS02070
uniprot id: W6RSL8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS05790
gene id: 1216932:CM240_RS05790
uniprot id: W6SF53
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS09800
gene id: 1216932:CM240_RS09800
uniprot id: W6SHH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1216932:CM240 RS11245
gene id: 1216932:CM240_RS11245
uniprot id: W6RXP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS13475
gene id: 1216932:CM240_RS13475
uniprot id: W6RYW6
names: Similarity
messages: Belongs to the AIR synthase family.

1216932:CM240 RS01940
gene id: 1216932:CM240_RS01940
uniprot id: W6SD56
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS10430
gene id: 1216932:CM240_RS10430
uniprot id: W6RXS6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1216932:CM240 RS09820
gene id: 1216932:CM240_RS09820
uniprot id: W6RZV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1216932:CM240 RS09060
gene id: 1216932:CM240_RS09060
uniprot id: W6RWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1216932:CM240 RS09670
gene id: 1216932:CM240_RS09670
uniprot id: W6RZS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS09700
gene id: 1216932:CM240_RS09700
uniprot id: W6SHE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1216932:CM240 RS13845
gene id: 1216932:CM240_RS13845
uniprot id: W6RZ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1216932:CM240 RS07885
gene id: 1216932:CM240_RS07885
uniprot id: W6RYR3
names: Subcellular Location Annotation
messages: Cytoplasm

1216932:CM240 RS05515
gene id: 1216932:CM240_RS05515
uniprot id: W6SF04
names: Similarity
messages: Belongs to the P(II) protein family.

1216932:CM240 RS07620
gene id: 1216932:CM240_RS07620
uniprot id: W6RYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1216932:CM240 RS12755
gene id: 1216932:CM240_RS12755
uniprot id: W6S5T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS08575
gene id: 1216932:CM240_RS08575
uniprot id: W6RX12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS05510
gene id: 1216932:CM240_RS05510
uniprot id: W6RXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS14570
gene id: 1216932:CM240_RS14570
uniprot id: W6RZI2
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS05410
gene id: 1216932:CM240_RS05410
uniprot id: W6RXA6
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS05280
gene id: 1216932:CM240_RS05280
uniprot id: W6RV79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1216932:CM240 RS12065
gene id: 1216932:CM240_RS12065
uniprot id: W6RYP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1216932:CM240 RS16915
gene id: 1216932:CM240_RS16915
uniprot id: W6S4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpsD/CapB family.
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1216932:CM240 RS12725
gene id: 1216932:CM240_RS12725
uniprot id: W6RYG4
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1216932:CM240 RS08550
gene id: 1216932:CM240_RS08550
uniprot id: W6RX10
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1216932:CM240 RS10375
gene id: 1216932:CM240_RS10375
uniprot id: W6RXR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1216932:CM240 RS12570
gene id: 1216932:CM240_RS12570
uniprot id: W6S5P0
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS05160
gene id: 1216932:CM240_RS05160
uniprot id: W6RX53
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1216932:CM240 RS14795
gene id: 1216932:CM240_RS14795
uniprot id: W6S2I2
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11875
gene id: 1216932:CM240_RS11875
uniprot id: W6SIQ3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1216932:CM240 RS15280
gene id: 1216932:CM240_RS15280
uniprot id: W6SK75
names: Similarity
messages: Belongs to the EamA transporter family.

1216932:CM240 RS16200
gene id: 1216932:CM240_RS16200
uniprot id: W6S114
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS11045
gene id: 1216932:CM240_RS11045
uniprot id: W6SI69
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1216932:CM240 RS09050
gene id: 1216932:CM240_RS09050
uniprot id: W6RZF6
names: Similarity
messages: Belongs to the acylphosphatase family.

1216932:CM240 RS13815
gene id: 1216932:CM240_RS13815
uniprot id: W6SJN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1216932:CM240 RS09270
gene id: 1216932:CM240_RS09270
uniprot id: W6RXA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1216932:CM240 RS09705
gene id: 1216932:CM240_RS09705
uniprot id: W6RWR2
names: Similarity
messages: Belongs to the UPF0297 family.

1216932:CM240 RS14620
gene id: 1216932:CM240_RS14620
uniprot id: W6S6R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1216932:CM240 RS14490
gene id: 1216932:CM240_RS14490
uniprot id: W6SJY3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1216932:CM240 RS08865
gene id: 1216932:CM240_RS08865
uniprot id: W6S3Q0
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1216932:CM240 RS05275
gene id: 1216932:CM240_RS05275
uniprot id: W6S1R6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1216932:CM240 RS13795
gene id: 1216932:CM240_RS13795
uniprot id: W6RZ60
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1216932:CM240 RS09400
gene id: 1216932:CM240_RS09400
uniprot id: W6SHA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS06730
gene id: 1216932:CM240_RS06730
uniprot id: W6S2J9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1216932:CM240 RS15230
gene id: 1216932:CM240_RS15230
uniprot id: W6SK67
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS16640
gene id: 1216932:CM240_RS16640
uniprot id: W6RRX4
names: Similarity
messages: Belongs to the peptidase C40 family.

1216932:CM240 RS13390
gene id: 1216932:CM240_RS13390
uniprot id: W6S1R0
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS09490
gene id: 1216932:CM240_RS09490
uniprot id: W6RXD4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1216932:CM240 RS09640
gene id: 1216932:CM240_RS09640
uniprot id: W6RXE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1216932:CM240 RS03915
gene id: 1216932:CM240_RS03915
uniprot id: W6RTN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1216932:CM240 RS05440
gene id: 1216932:CM240_RS05440
uniprot id: W6SEZ3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1216932:CM240 RS16725
gene id: 1216932:CM240_RS16725
uniprot id: W6RUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AgrB family.
messages: Cell membrane
messages: May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.

1216932:CM240 RS11585
gene id: 1216932:CM240_RS11585
uniprot id: W6S571
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1216932:CM240 RS16065
gene id: 1216932:CM240_RS16065
uniprot id: W6S383
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1216932:CM240 RS01900
gene id: 1216932:CM240_RS01900
uniprot id: W6RZW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS05095
gene id: 1216932:CM240_RS05095
uniprot id: W6RX37
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS09835
gene id: 1216932:CM240_RS09835
uniprot id: W6S481
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1216932:CM240 RS08735
gene id: 1216932:CM240_RS08735
uniprot id: W6SGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

1216932:CM240 RS01305
gene id: 1216932:CM240_RS01305
uniprot id: W6RZK2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1216932:CM240 RS02885
gene id: 1216932:CM240_RS02885
uniprot id: W6RT09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1216932:CM240 RS08520
gene id: 1216932:CM240_RS08520
uniprot id: W6S3J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1216932:CM240 RS01285
gene id: 1216932:CM240_RS01285
uniprot id: W6RT57
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS16190
gene id: 1216932:CM240_RS16190
uniprot id: W6S0J1
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS09630
gene id: 1216932:CM240_RS09630
uniprot id: W6RWP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

1216932:CM240 RS04400
gene id: 1216932:CM240_RS04400
uniprot id: W6RWP4
names: Similarity
messages: Belongs to the peptidase M29 family.

1216932:CM240 RS12560
gene id: 1216932:CM240_RS12560
uniprot id: W6RYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1216932:CM240 RS04485
gene id: 1216932:CM240_RS04485
uniprot id: W6S1A6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS07450
gene id: 1216932:CM240_RS07450
uniprot id: W6RVF3
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1216932:CM240 RS04015
gene id: 1216932:CM240_RS04015
uniprot id: W6RTQ2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1216932:CM240 RS16030
gene id: 1216932:CM240_RS16030
uniprot id: W6SKH0
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS01140
gene id: 1216932:CM240_RS01140
uniprot id: W6RT34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS00620
gene id: 1216932:CM240_RS00620
uniprot id: W6SCF6
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS08160
gene id: 1216932:CM240_RS08160
uniprot id: W6SGG7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1216932:CM240 RS12860
gene id: 1216932:CM240_RS12860
uniprot id: W6S5V0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1216932:CM240 RS02815
gene id: 1216932:CM240_RS02815
uniprot id: W6S0D2
names: Similarity
messages: Belongs to the glutamate synthase family.

1216932:CM240 RS05775
gene id: 1216932:CM240_RS05775
uniprot id: W6S1Z5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1216932:CM240 RS01965
gene id: 1216932:CM240_RS01965
uniprot id: W6SD60
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS08440
gene id: 1216932:CM240_RS08440
uniprot id: W6RVZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1216932:CM240 RS00930
gene id: 1216932:CM240_RS00930
uniprot id: W6RZA1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1216932:CM240 RS13860
gene id: 1216932:CM240_RS13860
uniprot id: W6S220
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1216932:CM240 RS13615
gene id: 1216932:CM240_RS13615
uniprot id: W6SJI4
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS02705
gene id: 1216932:CM240_RS02705
uniprot id: W6SDI3
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1216932:CM240 RS03605
gene id: 1216932:CM240_RS03605
uniprot id: W6RUC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1216932:CM240 RS11740
gene id: 1216932:CM240_RS11740
uniprot id: W6RYI9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1216932:CM240 RS09130
gene id: 1216932:CM240_RS09130
uniprot id: W6SH54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS11650
gene id: 1216932:CM240_RS11650
uniprot id: W6SIL0
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1216932:CM240 RS02255
gene id: 1216932:CM240_RS02255
uniprot id: W6RSP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1216932:CM240 RS02010
gene id: 1216932:CM240_RS02010
uniprot id: W6RVE9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1216932:CM240 RS04320
gene id: 1216932:CM240_RS04320
uniprot id: W6RUQ1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1216932:CM240 RS13080
gene id: 1216932:CM240_RS13080
uniprot id: W6RYP4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1216932:CM240 RS07195
gene id: 1216932:CM240_RS07195
uniprot id: W6SFY7
names: Similarity
messages: Belongs to the asp23 family.

1216932:CM240 RS07915
gene id: 1216932:CM240_RS07915
uniprot id: W6SGB7
names: Similarity
messages: Belongs to the UPF0749 family.

1216932:CM240 RS12075
gene id: 1216932:CM240_RS12075
uniprot id: W6SIT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1216932:CM240 RS07070
gene id: 1216932:CM240_RS07070
uniprot id: W6SFW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1216932:CM240 RS01175
gene id: 1216932:CM240_RS01175
uniprot id: W6SCU7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1216932:CM240 RS02085
gene id: 1216932:CM240_RS02085
uniprot id: W6RVG5
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1216932:CM240 RS09210
gene id: 1216932:CM240_RS09210
uniprot id: W6RWG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1216932:CM240 RS01500
gene id: 1216932:CM240_RS01500
uniprot id: W6SCZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS05460
gene id: 1216932:CM240_RS05460
uniprot id: W6RXB7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS05110
gene id: 1216932:CM240_RS05110
uniprot id: W6S1N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1216932:CM240 RS04370
gene id: 1216932:CM240_RS04370
uniprot id: W6RUQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1216932:CM240 RS01290
gene id: 1216932:CM240_RS01290
uniprot id: W6RV07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS03550
gene id: 1216932:CM240_RS03550
uniprot id: W6S0U4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1216932:CM240 RS03410
gene id: 1216932:CM240_RS03410
uniprot id: W6RW47
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12730
gene id: 1216932:CM240_RS12730
uniprot id: W6S5S8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1216932:CM240 RS08905
gene id: 1216932:CM240_RS08905
uniprot id: W6SH18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1216932:CM240 RS04455
gene id: 1216932:CM240_RS04455
uniprot id: W6SEI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1216932:CM240 RS09515
gene id: 1216932:CM240_RS09515
uniprot id: W6RXD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1216932:CM240 RS14270
gene id: 1216932:CM240_RS14270
uniprot id: W6S287
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1216932:CM240 RS13185
gene id: 1216932:CM240_RS13185
uniprot id: W6SJC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1216932:CM240 RS08490
gene id: 1216932:CM240_RS08490
uniprot id: W6RW00
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1216932:CM240 RS13865
gene id: 1216932:CM240_RS13865
uniprot id: W6SJP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1216932:CM240 RS06040
gene id: 1216932:CM240_RS06040
uniprot id: W6RUR9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1216932:CM240 RS01030
gene id: 1216932:CM240_RS01030
uniprot id: W6RS32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1216932:CM240 RS03750
gene id: 1216932:CM240_RS03750
uniprot id: W6RUF3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1216932:CM240 RS05245
gene id: 1216932:CM240_RS05245
uniprot id: W6RUC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

1216932:CM240 RS04680
gene id: 1216932:CM240_RS04680
uniprot id: W6RWV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1216932:CM240 RS07315
gene id: 1216932:CM240_RS07315
uniprot id: W6RYD2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1216932:CM240 RS05435
gene id: 1216932:CM240_RS05435
uniprot id: W6RXB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1216932:CM240 RS07900
gene id: 1216932:CM240_RS07900
uniprot id: W6S369
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1216932:CM240 RS05570
gene id: 1216932:CM240_RS05570
uniprot id: W6RUG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS06670
gene id: 1216932:CM240_RS06670
uniprot id: W6SFQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS00805
gene id: 1216932:CM240_RS00805
uniprot id: W6RUP6
names: Similarity
messages: Belongs to the peptidase C40 family.

1216932:CM240 RS12185
gene id: 1216932:CM240_RS12185
uniprot id: W6S5H4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1216932:CM240 RS11340
gene id: 1216932:CM240_RS11340
uniprot id: W6SIG0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1216932:CM240 RS07185
gene id: 1216932:CM240_RS07185
uniprot id: W6RW49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1216932:CM240 RS09650
gene id: 1216932:CM240_RS09650
uniprot id: W6SHE1
names: Similarity
messages: Belongs to the GSP E family.

1216932:CM240 RS05140
gene id: 1216932:CM240_RS05140
uniprot id: W6SEU5
names: Similarity
messages: Belongs to the TelA family.

1216932:CM240 RS12870
gene id: 1216932:CM240_RS12870
uniprot id: W6S1H5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1216932:CM240 RS04545
gene id: 1216932:CM240_RS04545
uniprot id: W6RU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1216932:CM240 RS05545
gene id: 1216932:CM240_RS05545
uniprot id: W6RUG4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1216932:CM240 RS09095
gene id: 1216932:CM240_RS09095
uniprot id: W6RX81
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1216932:CM240 RS07145
gene id: 1216932:CM240_RS07145
uniprot id: W6SFX8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1216932:CM240 RS10565
gene id: 1216932:CM240_RS10565
uniprot id: W6SHU4
names: Similarity
messages: Belongs to the GARS family.

1216932:CM240 RS07160
gene id: 1216932:CM240_RS07160
uniprot id: W6RW45
names: Similarity
messages: Belongs to the TlyA family.

1216932:CM240 RS07865
gene id: 1216932:CM240_RS07865
uniprot id: W6SGB0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1216932:CM240 RS15600
gene id: 1216932:CM240_RS15600
uniprot id: W6S2Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS13850
gene id: 1216932:CM240_RS13850
uniprot id: W6S6C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS00825
gene id: 1216932:CM240_RS00825
uniprot id: W6RSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

1216932:CM240 RS07415
gene id: 1216932:CM240_RS07415
uniprot id: W6RYF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1216932:CM240 RS01445
gene id: 1216932:CM240_RS01445
uniprot id: W6RV34
names: Similarity
messages: Belongs to the DtxR/MntR family.

1216932:CM240 RS02020
gene id: 1216932:CM240_RS02020
uniprot id: W6RSL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1216932:CM240 RS12200
gene id: 1216932:CM240_RS12200
uniprot id: W6SIV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1216932:CM240 RS13630
gene id: 1216932:CM240_RS13630
uniprot id: W6RZG8
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS06625
gene id: 1216932:CM240_RS06625
uniprot id: W6RV08
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1216932:CM240 RS11525
gene id: 1216932:CM240_RS11525
uniprot id: W6S0U5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1216932:CM240 RS07175
gene id: 1216932:CM240_RS07175
uniprot id: W6RVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1216932:CM240 RS02805
gene id: 1216932:CM240_RS02805
uniprot id: W6SDK5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS12635
gene id: 1216932:CM240_RS12635
uniprot id: W6S5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1216932:CM240 RS03240
gene id: 1216932:CM240_RS03240
uniprot id: W6SDU0
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1216932:CM240 RS13170
gene id: 1216932:CM240_RS13170
uniprot id: W6S603
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1216932:CM240 RS05930
gene id: 1216932:CM240_RS05930
uniprot id: W6RVL1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1216932:CM240 RS12155
gene id: 1216932:CM240_RS12155
uniprot id: W6RY56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1216932:CM240 RS10065
gene id: 1216932:CM240_RS10065
uniprot id: W6RXL5
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1216932:CM240 RS12095
gene id: 1216932:CM240_RS12095
uniprot id: W6S137
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1216932:CM240 RS11880
gene id: 1216932:CM240_RS11880
uniprot id: W6RY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1216932:CM240 RS11975
gene id: 1216932:CM240_RS11975
uniprot id: W6SIS0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1216932:CM240 RS12470
gene id: 1216932:CM240_RS12470
uniprot id: W6RYV0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1216932:CM240 RS06110
gene id: 1216932:CM240_RS06110
uniprot id: W6RUS9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1216932:CM240 RS04775
gene id: 1216932:CM240_RS04775
uniprot id: W6RWX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1216932:CM240 RS14730
gene id: 1216932:CM240_RS14730
uniprot id: W6S2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1216932:CM240 RS08105
gene id: 1216932:CM240_RS08105
uniprot id: W6RYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS11800
gene id: 1216932:CM240_RS11800
uniprot id: W6SIN5
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS03155
gene id: 1216932:CM240_RS03155
uniprot id: W6RU28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1216932:CM240 RS02340
gene id: 1216932:CM240_RS02340
uniprot id: W6RSR4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS06680
gene id: 1216932:CM240_RS06680
uniprot id: W6S2J0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS10620
gene id: 1216932:CM240_RS10620
uniprot id: W6RXA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS02355
gene id: 1216932:CM240_RS02355
uniprot id: W6RVL5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1216932:CM240 RS09655
gene id: 1216932:CM240_RS09655
uniprot id: W6RWQ1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1216932:CM240 RS08975
gene id: 1216932:CM240_RS08975
uniprot id: W6RZE6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1216932:CM240 RS10680
gene id: 1216932:CM240_RS10680
uniprot id: W6RXX9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1216932:CM240 RS01925
gene id: 1216932:CM240_RS01925
uniprot id: W6RZW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS09370
gene id: 1216932:CM240_RS09370
uniprot id: W6RZL0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1216932:CM240 RS13880
gene id: 1216932:CM240_RS13880
uniprot id: W6RZP6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1216932:CM240 RS12895
gene id: 1216932:CM240_RS12895
uniprot id: W6S1H8
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS07855
gene id: 1216932:CM240_RS07855
uniprot id: W6RWK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1216932:CM240 RS04505
gene id: 1216932:CM240_RS04505
uniprot id: W6RTZ7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1216932:CM240 RS08885
gene id: 1216932:CM240_RS08885
uniprot id: W6RWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1216932:CM240 RS02170
gene id: 1216932:CM240_RS02170
uniprot id: W6RSN3
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS09960
gene id: 1216932:CM240_RS09960
uniprot id: W6S4A4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1216932:CM240 RS13315
gene id: 1216932:CM240_RS13315
uniprot id: W6SJE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1216932:CM240 RS02140
gene id: 1216932:CM240_RS02140
uniprot id: W6SD86
names: Similarity
messages: Belongs to the ArsC family.

1216932:CM240 RS14450
gene id: 1216932:CM240_RS14450
uniprot id: W6S6N4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1216932:CM240 RS15385
gene id: 1216932:CM240_RS15385
uniprot id: W6S0F8
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1216932:CM240 RS09895
gene id: 1216932:CM240_RS09895
uniprot id: W6RZW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS05385
gene id: 1216932:CM240_RS05385
uniprot id: W6RXA3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1216932:CM240 RS11290
gene id: 1216932:CM240_RS11290
uniprot id: W6SIF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1216932:CM240 RS00950
gene id: 1216932:CM240_RS00950
uniprot id: W6RS02
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1216932:CM240 RS10280
gene id: 1216932:CM240_RS10280
uniprot id: W6SHP4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1216932:CM240 RS15975
gene id: 1216932:CM240_RS15975
uniprot id: W6S368
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1216932:CM240 RS02055
gene id: 1216932:CM240_RS02055
uniprot id: W6RTH9
names: Similarity
messages: Belongs to the citrate synthase family.

1216932:CM240 RS17040
gene id: 1216932:CM240_RS17040
uniprot id: W6SKE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1216932:CM240 RS00780
gene id: 1216932:CM240_RS00780
uniprot id: W6RUN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1216932:CM240 RS14710
gene id: 1216932:CM240_RS14710
uniprot id: W6SK09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS07445
gene id: 1216932:CM240_RS07445
uniprot id: W6SG35
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1216932:CM240 RS13285
gene id: 1216932:CM240_RS13285
uniprot id: W6SJD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1216932:CM240 RS12060
gene id: 1216932:CM240_RS12060
uniprot id: W6S5E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1216932:CM240 RS02490
gene id: 1216932:CM240_RS02490
uniprot id: W6S075
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1216932:CM240 RS03725
gene id: 1216932:CM240_RS03725
uniprot id: W6RUF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1216932:CM240 RS00605
gene id: 1216932:CM240_RS00605
uniprot id: W6RZ37
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1216932:CM240 RS05670
gene id: 1216932:CM240_RS05670
uniprot id: W6RUI4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1216932:CM240 RS14105
gene id: 1216932:CM240_RS14105
uniprot id: W6RZA7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1216932:CM240 RS12965
gene id: 1216932:CM240_RS12965
uniprot id: W6RZ43
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1216932:CM240 RS02410
gene id: 1216932:CM240_RS02410
uniprot id: W6SDD9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1216932:CM240 RS04350
gene id: 1216932:CM240_RS04350
uniprot id: W6RWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1216932:CM240 RS16805
gene id: 1216932:CM240_RS16805
uniprot id: W6SF38
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1216932:CM240 RS08280
gene id: 1216932:CM240_RS08280
uniprot id: W6RYZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1216932:CM240 RS06490
gene id: 1216932:CM240_RS06490
uniprot id: W6RUY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1216932:CM240 RS08375
gene id: 1216932:CM240_RS08375
uniprot id: W6RWV9
names: Similarity
messages: Belongs to the peptidase S14 family.

1216932:CM240 RS04695
gene id: 1216932:CM240_RS04695
uniprot id: W6S1E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS10595
gene id: 1216932:CM240_RS10595
uniprot id: W6RXA0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1216932:CM240 RS09870
gene id: 1216932:CM240_RS09870
uniprot id: W6RZW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1216932:CM240 RS11085
gene id: 1216932:CM240_RS11085
uniprot id: W6SIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1216932:CM240 RS07265
gene id: 1216932:CM240_RS07265
uniprot id: W6RYC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1216932:CM240 RS05760
gene id: 1216932:CM240_RS05760
uniprot id: W6RXH2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1216932:CM240 RS12985
gene id: 1216932:CM240_RS12985
uniprot id: W6S5X6
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS07310
gene id: 1216932:CM240_RS07310
uniprot id: W6RW69
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1216932:CM240 RS05990
gene id: 1216932:CM240_RS05990
uniprot id: W6RUR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1216932:CM240 RS03850
gene id: 1216932:CM240_RS03850
uniprot id: W6RUH2
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12835
gene id: 1216932:CM240_RS12835
uniprot id: W6S5U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1216932:CM240 RS12890
gene id: 1216932:CM240_RS12890
uniprot id: W6RZ28
names: Similarity
messages: Belongs to the UPF0237 family.

1216932:CM240 RS00285
gene id: 1216932:CM240_RS00285
uniprot id: W6SC87
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS10380
gene id: 1216932:CM240_RS10380
uniprot id: W6S069
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1216932:CM240 RS02565
gene id: 1216932:CM240_RS02565
uniprot id: W6S088
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1216932:CM240 RS11915
gene id: 1216932:CM240_RS11915
uniprot id: W6RYL8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1216932:CM240 RS02660
gene id: 1216932:CM240_RS02660
uniprot id: W6RSX1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1216932:CM240 RS00395
gene id: 1216932:CM240_RS00395
uniprot id: W6RUE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1216932:CM240 RS09525
gene id: 1216932:CM240_RS09525
uniprot id: W6SHC0
names: Similarity
messages: Belongs to the YicC/YloC family.

1216932:CM240 RS08685
gene id: 1216932:CM240_RS08685
uniprot id: W6SGY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1216932:CM240 RS04630
gene id: 1216932:CM240_RS04630
uniprot id: W6RWU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS12130
gene id: 1216932:CM240_RS12130
uniprot id: W6RY52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1216932:CM240 RS07080
gene id: 1216932:CM240_RS07080
uniprot id: W6S2Q8
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1216932:CM240 RS10120
gene id: 1216932:CM240_RS10120
uniprot id: W6S016
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1216932:CM240 RS10305
gene id: 1216932:CM240_RS10305
uniprot id: W6S054
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1216932:CM240 RS05520
gene id: 1216932:CM240_RS05520
uniprot id: W6RUF9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1216932:CM240 RS09295
gene id: 1216932:CM240_RS09295
uniprot id: W6RXA5
names: Similarity
messages: Belongs to the NAPRTase family.

1216932:CM240 RS02810
gene id: 1216932:CM240_RS02810
uniprot id: W6RSZ7
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1216932:CM240 RS08745
gene id: 1216932:CM240_RS08745
uniprot id: W6S3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1216932:CM240 RS09425
gene id: 1216932:CM240_RS09425
uniprot id: W6SHA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1216932:CM240 RS08995
gene id: 1216932:CM240_RS08995
uniprot id: W6RX70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS04915
gene id: 1216932:CM240_RS04915
uniprot id: W6S1J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1216932:CM240 RS07585
gene id: 1216932:CM240_RS07585
uniprot id: W6S308
names: Similarity
messages: Belongs to the catalase family.

1216932:CM240 RS07765
gene id: 1216932:CM240_RS07765
uniprot id: W6RYN4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1216932:CM240 RS13890
gene id: 1216932:CM240_RS13890
uniprot id: W6SJQ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS11865
gene id: 1216932:CM240_RS11865
uniprot id: W6RYK8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1216932:CM240 RS09620
gene id: 1216932:CM240_RS09620
uniprot id: W6RZR1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1216932:CM240 RS11390
gene id: 1216932:CM240_RS11390
uniprot id: W6SIG7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS13685
gene id: 1216932:CM240_RS13685
uniprot id: W6S1X5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1216932:CM240 RS08010
gene id: 1216932:CM240_RS08010
uniprot id: W6RYT4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1216932:CM240 RS08385
gene id: 1216932:CM240_RS08385
uniprot id: W6SGL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1216932:CM240 RS14790
gene id: 1216932:CM240_RS14790
uniprot id: W6S058
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1216932:CM240 RS03760
gene id: 1216932:CM240_RS03760
uniprot id: W6SE74
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1216932:CM240 RS16240
gene id: 1216932:CM240_RS16240
uniprot id: W6S3E7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12655
gene id: 1216932:CM240_RS12655
uniprot id: W6RYE8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1216932:CM240 RS09605
gene id: 1216932:CM240_RS09605
uniprot id: W6RWP1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1216932:CM240 RS08880
gene id: 1216932:CM240_RS08880
uniprot id: W6SH13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1216932:CM240 RS10150
gene id: 1216932:CM240_RS10150
uniprot id: W6SHM6
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1216932:CM240 RS09140
gene id: 1216932:CM240_RS09140
uniprot id: W6S3V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1216932:CM240 RS07380
gene id: 1216932:CM240_RS07380
uniprot id: W6S2X1
names: Similarity
messages: Belongs to the RutC family.

1216932:CM240 RS03610
gene id: 1216932:CM240_RS03610
uniprot id: W6RWA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1216932:CM240 RS08450
gene id: 1216932:CM240_RS08450
uniprot id: W6RWX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1216932:CM240 RS09120
gene id: 1216932:CM240_RS09120
uniprot id: W6RX84
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1216932:CM240 RS08310
gene id: 1216932:CM240_RS08310
uniprot id: W6SGJ8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1216932:CM240 RS00310
gene id: 1216932:CM240_RS00310
uniprot id: W6RRN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1216932:CM240 RS05650
gene id: 1216932:CM240_RS05650
uniprot id: W6S1X3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1216932:CM240 RS05780
gene id: 1216932:CM240_RS05780
uniprot id: W6RVI2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1216932:CM240 RS07725
gene id: 1216932:CM240_RS07725
uniprot id: W6SG85
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1216932:CM240 RS14120
gene id: 1216932:CM240_RS14120
uniprot id: W6S263
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS07960
gene id: 1216932:CM240_RS07960
uniprot id: W6RYS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1216932:CM240 RS08120
gene id: 1216932:CM240_RS08120
uniprot id: W6S3A2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1216932:CM240 RS00490
gene id: 1216932:CM240_RS00490
uniprot id: W6RSQ8
names: Similarity
messages: Belongs to the EamA transporter family.

1216932:CM240 RS13050
gene id: 1216932:CM240_RS13050
uniprot id: W6SJA6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1216932:CM240 RS11200
gene id: 1216932:CM240_RS11200
uniprot id: W6S520
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1216932:CM240 RS03570
gene id: 1216932:CM240_RS03570
uniprot id: W6RTH0
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

1216932:CM240 RS04970
gene id: 1216932:CM240_RS04970
uniprot id: W6RX11
names: Similarity
messages: Belongs to the CFA/CMAS family.

1216932:CM240 RS11330
gene id: 1216932:CM240_RS11330
uniprot id: W6RYB2
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS07505
gene id: 1216932:CM240_RS07505
uniprot id: W6S2Z5
names: Similarity
messages: Belongs to the UPF0735 family.

1216932:CM240 RS03005
gene id: 1216932:CM240_RS03005
uniprot id: W6RU03
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1216932:CM240 RS09545
gene id: 1216932:CM240_RS09545
uniprot id: W6RZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1216932:CM240 RS08585
gene id: 1216932:CM240_RS08585
uniprot id: W6SGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1216932:CM240 RS06065
gene id: 1216932:CM240_RS06065
uniprot id: W6RUS2
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.

1216932:CM240 RS09710
gene id: 1216932:CM240_RS09710
uniprot id: W6S460
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1216932:CM240 RS08480
gene id: 1216932:CM240_RS08480
uniprot id: W6RZ30
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS09375
gene id: 1216932:CM240_RS09375
uniprot id: W6SH97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1216932:CM240 RS01390
gene id: 1216932:CM240_RS01390
uniprot id: W6RT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1216932:CM240 RS07125
gene id: 1216932:CM240_RS07125
uniprot id: W6RV93
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS08430
gene id: 1216932:CM240_RS08430
uniprot id: W6RZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1216932:CM240 RS12055
gene id: 1216932:CM240_RS12055
uniprot id: W6RY38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1216932:CM240 RS08005
gene id: 1216932:CM240_RS08005
uniprot id: W6RWN2
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1216932:CM240 RS08770
gene id: 1216932:CM240_RS08770
uniprot id: W6S3N3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1216932:CM240 RS01455
gene id: 1216932:CM240_RS01455
uniprot id: W6RSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1216932:CM240 RS05915
gene id: 1216932:CM240_RS05915
uniprot id: W6SF74
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1216932:CM240 RS12840
gene id: 1216932:CM240_RS12840
uniprot id: W6RZ20
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

1216932:CM240 RS14645
gene id: 1216932:CM240_RS14645
uniprot id: W6S6R8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1216932:CM240 RS12025
gene id: 1216932:CM240_RS12025
uniprot id: W6SIS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1216932:CM240 RS15440
gene id: 1216932:CM240_RS15440
uniprot id: W6S2V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1216932:CM240 RS09460
gene id: 1216932:CM240_RS09460
uniprot id: W6S421
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1216932:CM240 RS16040
gene id: 1216932:CM240_RS16040
uniprot id: W6S0T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AgrB family.
messages: Cell membrane
messages: May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.

1216932:CM240 RS11630
gene id: 1216932:CM240_RS11630
uniprot id: W6RXV9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS05265
gene id: 1216932:CM240_RS05265
uniprot id: W6SEW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1216932:CM240 RS04300
gene id: 1216932:CM240_RS04300
uniprot id: W6RWM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1216932:CM240 RS07575
gene id: 1216932:CM240_RS07575
uniprot id: W6SG58
names: Similarity
messages: Belongs to the ArsC family.

1216932:CM240 RS06510
gene id: 1216932:CM240_RS06510
uniprot id: W6S2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1216932:CM240 RS07945
gene id: 1216932:CM240_RS07945
uniprot id: W6RVN8
names: Similarity
messages: Belongs to the transpeptidase family.

1216932:CM240 RS11860
gene id: 1216932:CM240_RS11860
uniprot id: W6S5B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1216932:CM240 RS02685
gene id: 1216932:CM240_RS02685
uniprot id: W6RSX5
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS10465
gene id: 1216932:CM240_RS10465
uniprot id: W6SHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS07350
gene id: 1216932:CM240_RS07350
uniprot id: W6RVD6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1216932:CM240 RS08470
gene id: 1216932:CM240_RS08470
uniprot id: W6S3H2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1216932:CM240 RS02460
gene id: 1216932:CM240_RS02460
uniprot id: W6RST7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12500
gene id: 1216932:CM240_RS12500
uniprot id: W6S1A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1216932:CM240 RS11945
gene id: 1216932:CM240_RS11945
uniprot id: W6S111
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1216932:CM240 RS10285
gene id: 1216932:CM240_RS10285
uniprot id: W6RX30
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1216932:CM240 RS04855
gene id: 1216932:CM240_RS04855
uniprot id: W6SEQ1
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS15935
gene id: 1216932:CM240_RS15935
uniprot id: W6S0B3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1216932:CM240 RS01945
gene id: 1216932:CM240_RS01945
uniprot id: W6RSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS12625
gene id: 1216932:CM240_RS12625
uniprot id: W6SJ20
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS16645
gene id: 1216932:CM240_RS16645
uniprot id: W6RSW4
names: Similarity
messages: Belongs to the peptidase C40 family.

1216932:CM240 RS14750
gene id: 1216932:CM240_RS14750
uniprot id: W6S049
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1216932:CM240 RS09845
gene id: 1216932:CM240_RS09845
uniprot id: W6RZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1216932:CM240 RS04450
gene id: 1216932:CM240_RS04450
uniprot id: W6RWQ2
names: Similarity
messages: Belongs to the peptidase M18 family.

1216932:CM240 RS16565
gene id: 1216932:CM240_RS16565
uniprot id: W6S3J4
names: Similarity
messages: Belongs to the peptidase A8 family.

1216932:CM240 RS10915
gene id: 1216932:CM240_RS10915
uniprot id: W6RY11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1216932:CM240 RS15155
gene id: 1216932:CM240_RS15155
uniprot id: W6SK54
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1216932:CM240 RS11265
gene id: 1216932:CM240_RS11265
uniprot id: W6SIE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS08710
gene id: 1216932:CM240_RS08710
uniprot id: W6SGY3
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS10655
gene id: 1216932:CM240_RS10655
uniprot id: W6RXX6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1216932:CM240 RS08110
gene id: 1216932:CM240_RS08110
uniprot id: W6SGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

1216932:CM240 RS15065
gene id: 1216932:CM240_RS15065
uniprot id: W6SK42
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11010
gene id: 1216932:CM240_RS11010
uniprot id: W6RY30
names: Similarity
messages: Belongs to the peptidase S66 family.

1216932:CM240 RS12720
gene id: 1216932:CM240_RS12720
uniprot id: W6SJ36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1216932:CM240 RS13830
gene id: 1216932:CM240_RS13830
uniprot id: W6RZN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1216932:CM240 RS07830
gene id: 1216932:CM240_RS07830
uniprot id: W6RWJ8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1216932:CM240 RS11345
gene id: 1216932:CM240_RS11345
uniprot id: W6RXQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1216932:CM240 RS12685
gene id: 1216932:CM240_RS12685
uniprot id: W6RYZ3
names: Similarity
messages: Belongs to the peptidase S8 family.

1216932:CM240 RS08605
gene id: 1216932:CM240_RS08605
uniprot id: W6RZ83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS01380
gene id: 1216932:CM240_RS01380
uniprot id: W6RSA6
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS00160
gene id: 1216932:CM240_RS00160
uniprot id: W6RRL9
names: Similarity
messages: Belongs to the class-I fumarase family.

1216932:CM240 RS02605
gene id: 1216932:CM240_RS02605
uniprot id: W6SDG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1216932:CM240 RS15340
gene id: 1216932:CM240_RS15340
uniprot id: W6S2U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS13290
gene id: 1216932:CM240_RS13290
uniprot id: W6RYT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1216932:CM240 RS04135
gene id: 1216932:CM240_RS04135
uniprot id: W6RWI9
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1216932:CM240 RS09810
gene id: 1216932:CM240_RS09810
uniprot id: W6S476
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS14965
gene id: 1216932:CM240_RS14965
uniprot id: W6SK32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS09395
gene id: 1216932:CM240_RS09395
uniprot id: W6RZL4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1216932:CM240 RS00030
gene id: 1216932:CM240_RS00030
uniprot id: W6RU96
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1216932:CM240 RS02670
gene id: 1216932:CM240_RS02670
uniprot id: W6RTU1
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1216932:CM240 RS10390
gene id: 1216932:CM240_RS10390
uniprot id: W6RX55
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS17860
gene id: 1216932:CM240_RS17860
uniprot id: W6S5Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1216932:CM240 RS11060
gene id: 1216932:CM240_RS11060
uniprot id: W6RY42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1216932:CM240 RS08355
gene id: 1216932:CM240_RS08355
uniprot id: W6RZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1216932:CM240 RS04820
gene id: 1216932:CM240_RS04820
uniprot id: W6RUY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS09795
gene id: 1216932:CM240_RS09795
uniprot id: W6RZU7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1216932:CM240 RS06530
gene id: 1216932:CM240_RS06530
uniprot id: W6RUZ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS05470
gene id: 1216932:CM240_RS05470
uniprot id: W6RUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1216932:CM240 RS13075
gene id: 1216932:CM240_RS13075
uniprot id: W6SJA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1216932:CM240 RS04900
gene id: 1216932:CM240_RS04900
uniprot id: W6RWZ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1216932:CM240 RS07470
gene id: 1216932:CM240_RS07470
uniprot id: W6SG40
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1216932:CM240 RS13070
gene id: 1216932:CM240_RS13070
uniprot id: W6S1L0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1216932:CM240 RS07375
gene id: 1216932:CM240_RS07375
uniprot id: W6RVE1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1216932:CM240 RS04790
gene id: 1216932:CM240_RS04790
uniprot id: W6S1G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1216932:CM240 RS08260
gene id: 1216932:CM240_RS08260
uniprot id: W6SGI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1216932:CM240 RS14785
gene id: 1216932:CM240_RS14785
uniprot id: W6S6U3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1216932:CM240 RS02325
gene id: 1216932:CM240_RS02325
uniprot id: W6S042
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1216932:CM240 RS07115
gene id: 1216932:CM240_RS07115
uniprot id: W6RY88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1216932:CM240 RS09045
gene id: 1216932:CM240_RS09045
uniprot id: W6RX75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS09600
gene id: 1216932:CM240_RS09600
uniprot id: W6SHD2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS11710
gene id: 1216932:CM240_RS11710
uniprot id: W6S587
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1216932:CM240 RS03010
gene id: 1216932:CM240_RS03010
uniprot id: W6RVY3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1216932:CM240 RS01135
gene id: 1216932:CM240_RS01135
uniprot id: W6RZH4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1216932:CM240 RS12705
gene id: 1216932:CM240_RS12705
uniprot id: W6S5S2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1216932:CM240 RS04735
gene id: 1216932:CM240_RS04735
uniprot id: W6RU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1216932:CM240 RS11325
gene id: 1216932:CM240_RS11325
uniprot id: W6S535
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1216932:CM240 RS09325
gene id: 1216932:CM240_RS09325
uniprot id: W6RZK1
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS01465
gene id: 1216932:CM240_RS01465
uniprot id: W6RT86
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1216932:CM240 RS01225
gene id: 1216932:CM240_RS01225
uniprot id: W6RS85
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS05175
gene id: 1216932:CM240_RS05175
uniprot id: W6S1P6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1216932:CM240 RS11785
gene id: 1216932:CM240_RS11785
uniprot id: W6S599
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1216932:CM240 RS06145
gene id: 1216932:CM240_RS06145
uniprot id: W6RVS0
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS14350
gene id: 1216932:CM240_RS14350
uniprot id: W6SJW7
names: Similarity
messages: Belongs to the peptidase S51 family.

1216932:CM240 RS18140
gene id: 1216932:CM240_RS18140
uniprot id: W6RUV8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1216932:CM240 RS03510
gene id: 1216932:CM240_RS03510
uniprot id: W6RW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS00085
gene id: 1216932:CM240_RS00085
uniprot id: W6SC58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1216932:CM240 RS04865
gene id: 1216932:CM240_RS04865
uniprot id: W6S1I2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1216932:CM240 RS05430
gene id: 1216932:CM240_RS05430
uniprot id: W6RVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1216932:CM240 RS08320
gene id: 1216932:CM240_RS08320
uniprot id: W6S3D9
names: Similarity
messages: Belongs to the FlgM family.

1216932:CM240 RS15780
gene id: 1216932:CM240_RS15780
uniprot id: W6SKD9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS08150
gene id: 1216932:CM240_RS08150
uniprot id: W6RWS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1216932:CM240 RS12070
gene id: 1216932:CM240_RS12070
uniprot id: W6S133
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1216932:CM240 RS04880
gene id: 1216932:CM240_RS04880
uniprot id: W6SEQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1216932:CM240 RS08500
gene id: 1216932:CM240_RS08500
uniprot id: W6RWY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1216932:CM240 RS06470
gene id: 1216932:CM240_RS06470
uniprot id: W6S2E6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS06355
gene id: 1216932:CM240_RS06355
uniprot id: W6RVU2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1216932:CM240 RS02380
gene id: 1216932:CM240_RS02380
uniprot id: W6RVM1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1216932:CM240 RS02595
gene id: 1216932:CM240_RS02595
uniprot id: W6RTS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1216932:CM240 RS00715
gene id: 1216932:CM240_RS00715
uniprot id: W6RRV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1216932:CM240 RS12345
gene id: 1216932:CM240_RS12345
uniprot id: W6RYT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS07130
gene id: 1216932:CM240_RS07130
uniprot id: W6S2R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1216932:CM240 RS04625
gene id: 1216932:CM240_RS04625
uniprot id: W6RUU6
names: Similarity
messages: Belongs to the EamA transporter family.

1216932:CM240 RS01025
gene id: 1216932:CM240_RS01025
uniprot id: W6SCR2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1216932:CM240 RS16810
gene id: 1216932:CM240_RS16810
uniprot id: W6S210
names: Similarity
messages: Belongs to the peptidase C40 family.

1216932:CM240 RS08555
gene id: 1216932:CM240_RS08555
uniprot id: W6RZ73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1216932:CM240 RS08870
gene id: 1216932:CM240_RS08870
uniprot id: W6RX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1216932:CM240 RS10580
gene id: 1216932:CM240_RS10580
uniprot id: W6RXW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS04750
gene id: 1216932:CM240_RS04750
uniprot id: W6RWW6
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1216932:CM240 RS09590
gene id: 1216932:CM240_RS09590
uniprot id: W6RXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1216932:CM240 RS15185
gene id: 1216932:CM240_RS15185
uniprot id: W6RZW1
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS15460
gene id: 1216932:CM240_RS15460
uniprot id: W6S2W3
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS10925
gene id: 1216932:CM240_RS10925
uniprot id: W6SI25
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1216932:CM240 RS08675
gene id: 1216932:CM240_RS08675
uniprot id: W6RX28
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1216932:CM240 RS08050
gene id: 1216932:CM240_RS08050
uniprot id: W6RWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1216932:CM240 RS04430
gene id: 1216932:CM240_RS04430
uniprot id: W6SEI0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1216932:CM240 RS03885
gene id: 1216932:CM240_RS03885
uniprot id: W6SE93
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1216932:CM240 RS07995
gene id: 1216932:CM240_RS07995
uniprot id: W6RVP8
names: Similarity
messages: Belongs to the MotB family.

1216932:CM240 RS11320
gene id: 1216932:CM240_RS11320
uniprot id: W6RXQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1216932:CM240 RS12250
gene id: 1216932:CM240_RS12250
uniprot id: W6S167
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1216932:CM240 RS09915
gene id: 1216932:CM240_RS09915
uniprot id: W6RXJ0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1216932:CM240 RS13055
gene id: 1216932:CM240_RS13055
uniprot id: W6RYN7
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS06610
gene id: 1216932:CM240_RS06610
uniprot id: W6RVX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS03775
gene id: 1216932:CM240_RS03775
uniprot id: W6RUF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1216932:CM240 RS07405
gene id: 1216932:CM240_RS07405
uniprot id: W6S2X5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1216932:CM240 RS15375
gene id: 1216932:CM240_RS15375
uniprot id: W6S003
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

1216932:CM240 RS02465
gene id: 1216932:CM240_RS02465
uniprot id: W6S072
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS09890
gene id: 1216932:CM240_RS09890
uniprot id: W6RXI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS17070
gene id: 1216932:CM240_RS17070
uniprot id: W6S7R0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1216932:CM240 RS04265
gene id: 1216932:CM240_RS04265
uniprot id: W6RTV0
names: Similarity
messages: Belongs to the peptidase M24B family.

1216932:CM240 RS09380
gene id: 1216932:CM240_RS09380
uniprot id: W6RWJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1216932:CM240 RS08570
gene id: 1216932:CM240_RS08570
uniprot id: W6S3K4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1216932:CM240 RS12105
gene id: 1216932:CM240_RS12105
uniprot id: W6RY48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1216932:CM240 RS04760
gene id: 1216932:CM240_RS04760
uniprot id: W6RU42
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1216932:CM240 RS04850
gene id: 1216932:CM240_RS04850
uniprot id: W6RWY7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS00710
gene id: 1216932:CM240_RS00710
uniprot id: W6SCH3
names: Similarity
messages: Belongs to the peptidase S66 family.

1216932:CM240 RS09435
gene id: 1216932:CM240_RS09435
uniprot id: W6S415
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1216932:CM240 RS02405
gene id: 1216932:CM240_RS02405
uniprot id: W6RVM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.

1216932:CM240 RS01040
gene id: 1216932:CM240_RS01040
uniprot id: W6RT19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1216932:CM240 RS05815
gene id: 1216932:CM240_RS05815
uniprot id: W6SF57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1216932:CM240 RS02365
gene id: 1216932:CM240_RS02365
uniprot id: W6RSR9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1216932:CM240 RS07685
gene id: 1216932:CM240_RS07685
uniprot id: W6S329
names: Similarity
messages: Belongs to the UPF0473 family.

1216932:CM240 RS10570
gene id: 1216932:CM240_RS10570
uniprot id: W6RX94
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1216932:CM240 RS10355
gene id: 1216932:CM240_RS10355
uniprot id: W6S064
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1216932:CM240 RS12395
gene id: 1216932:CM240_RS12395
uniprot id: W6S5L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS15970
gene id: 1216932:CM240_RS15970
uniprot id: W6S0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1216932:CM240 RS07485
gene id: 1216932:CM240_RS07485
uniprot id: W6RWC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1216932:CM240 RS08085
gene id: 1216932:CM240_RS08085
uniprot id: W6SGF1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1216932:CM240 RS08515
gene id: 1216932:CM240_RS08515
uniprot id: W6RW41
names: Similarity
messages: Belongs to the UPF0102 family.

1216932:CM240 RS05270
gene id: 1216932:CM240_RS05270
uniprot id: W6RUC7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS10405
gene id: 1216932:CM240_RS10405
uniprot id: W6S074
names: Similarity
messages: Belongs to the peptidase S8 family.

1216932:CM240 RS01620
gene id: 1216932:CM240_RS01620
uniprot id: W6SD15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS02575
gene id: 1216932:CM240_RS02575
uniprot id: W6RVQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1216932:CM240 RS07090
gene id: 1216932:CM240_RS07090
uniprot id: W6RY83
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1216932:CM240 RS14915
gene id: 1216932:CM240_RS14915
uniprot id: W6S2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS11310
gene id: 1216932:CM240_RS11310
uniprot id: W6S0R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1216932:CM240 RS10685
gene id: 1216932:CM240_RS10685
uniprot id: W6S0C6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1216932:CM240 RS10720
gene id: 1216932:CM240_RS10720
uniprot id: W6S4P6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1216932:CM240 RS12530
gene id: 1216932:CM240_RS12530
uniprot id: W6SJ04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1216932:CM240 RS12080
gene id: 1216932:CM240_RS12080
uniprot id: W6RY43
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1216932:CM240 RS09990
gene id: 1216932:CM240_RS09990
uniprot id: W6RXK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1216932:CM240 RS03465
gene id: 1216932:CM240_RS03465
uniprot id: W6SDY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1216932:CM240 RS09495
gene id: 1216932:CM240_RS09495
uniprot id: W6RZN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1216932:CM240 RS01245
gene id: 1216932:CM240_RS01245
uniprot id: W6SCV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1216932:CM240 RS15785
gene id: 1216932:CM240_RS15785
uniprot id: W6S087
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1216932:CM240 RS08445
gene id: 1216932:CM240_RS08445
uniprot id: W6S3G7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1216932:CM240 RS00155
gene id: 1216932:CM240_RS00155
uniprot id: W6SC68
names: Similarity
messages: Belongs to the class-I fumarase family.

1216932:CM240 RS09390
gene id: 1216932:CM240_RS09390
uniprot id: W6RXC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1216932:CM240 RS13340
gene id: 1216932:CM240_RS13340
uniprot id: W6S1Q2
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS15965
gene id: 1216932:CM240_RS15965
uniprot id: W6S7H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1216932:CM240 RS04395
gene id: 1216932:CM240_RS04395
uniprot id: W6RUQ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1216932:CM240 RS09940
gene id: 1216932:CM240_RS09940
uniprot id: W6RXJ5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1216932:CM240 RS10225
gene id: 1216932:CM240_RS10225
uniprot id: W6SHN8
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11635
gene id: 1216932:CM240_RS11635
uniprot id: W6S576
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1216932:CM240 RS13785
gene id: 1216932:CM240_RS13785
uniprot id: W6S207
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1216932:CM240 RS09480
gene id: 1216932:CM240_RS09480
uniprot id: W6RWL5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1216932:CM240 RS14900
gene id: 1216932:CM240_RS14900
uniprot id: W6RZP9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS02290
gene id: 1216932:CM240_RS02290
uniprot id: W6SDB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1216932:CM240 RS07075
gene id: 1216932:CM240_RS07075
uniprot id: W6RV84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1216932:CM240 RS11675
gene id: 1216932:CM240_RS11675
uniprot id: W6SIL4
names: Similarity
messages: Belongs to the peptidase S41A family.

1216932:CM240 RS08890
gene id: 1216932:CM240_RS08890
uniprot id: W6S3Q3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1216932:CM240 RS06405
gene id: 1216932:CM240_RS06405
uniprot id: W6RVU7
names: Similarity
messages: Belongs to the peptidase M18 family.

1216932:CM240 RS03995
gene id: 1216932:CM240_RS03995
uniprot id: W6S112
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1216932:CM240 RS02035
gene id: 1216932:CM240_RS02035
uniprot id: W6RVF4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1216932:CM240 RS12140
gene id: 1216932:CM240_RS12140
uniprot id: W6RYQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1216932:CM240 RS10855
gene id: 1216932:CM240_RS10855
uniprot id: W6RXE8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1216932:CM240 RS13610
gene id: 1216932:CM240_RS13610
uniprot id: W6S1U9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS10945
gene id: 1216932:CM240_RS10945
uniprot id: W6S0G5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1216932:CM240 RS11275
gene id: 1216932:CM240_RS11275
uniprot id: W6S530
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1216932:CM240 RS04945
gene id: 1216932:CM240_RS04945
uniprot id: W6RX06
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS00850
gene id: 1216932:CM240_RS00850
uniprot id: W6RSX6
names: Similarity
messages: Belongs to the PspA/IM30 family.

1216932:CM240 RS04710
gene id: 1216932:CM240_RS04710
uniprot id: W6RU34
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1216932:CM240 RS09005
gene id: 1216932:CM240_RS09005
uniprot id: W6SH34
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1216932:CM240 RS12390
gene id: 1216932:CM240_RS12390
uniprot id: W6RY94
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1216932:CM240 RS09830
gene id: 1216932:CM240_RS09830
uniprot id: W6RWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS05945
gene id: 1216932:CM240_RS05945
uniprot id: W6RUN4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1216932:CM240 RS02215
gene id: 1216932:CM240_RS02215
uniprot id: W6RTJ9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS08035
gene id: 1216932:CM240_RS08035
uniprot id: W6SGE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1216932:CM240 RS13385
gene id: 1216932:CM240_RS13385
uniprot id: W6RZB6
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS07385
gene id: 1216932:CM240_RS07385
uniprot id: W6RW87
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1216932:CM240 RS12110
gene id: 1216932:CM240_RS12110
uniprot id: W6S5F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1216932:CM240 RS15165
gene id: 1216932:CM240_RS15165
uniprot id: W6S701
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1216932:CM240 RS07335
gene id: 1216932:CM240_RS07335
uniprot id: W6RW77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1216932:CM240 RS10590
gene id: 1216932:CM240_RS10590
uniprot id: W6SHU6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1216932:CM240 RS14180
gene id: 1216932:CM240_RS14180
uniprot id: W6RZB9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS00215
gene id: 1216932:CM240_RS00215
uniprot id: W6RRM5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1216932:CM240 RS15980
gene id: 1216932:CM240_RS15980
uniprot id: W6SKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1216932:CM240 RS14150
gene id: 1216932:CM240_RS14150
uniprot id: W6SJU4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1216932:CM240 RS03190
gene id: 1216932:CM240_RS03190
uniprot id: W6SDT0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1216932:CM240 RS13855
gene id: 1216932:CM240_RS13855
uniprot id: W6RZP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1216932:CM240 RS06665
gene id: 1216932:CM240_RS06665
uniprot id: W6RY17
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS07025
gene id: 1216932:CM240_RS07025
uniprot id: W6RV73
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1216932:CM240 RS05665
gene id: 1216932:CM240_RS05665
uniprot id: W6SF26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1216932:CM240 RS03565
gene id: 1216932:CM240_RS03565
uniprot id: W6SE42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1216932:CM240 RS01155
gene id: 1216932:CM240_RS01155
uniprot id: W6RS72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1216932:CM240 RS12260
gene id: 1216932:CM240_RS12260
uniprot id: W6RY74
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1216932:CM240 RS11870
gene id: 1216932:CM240_RS11870
uniprot id: W6S0Z8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1216932:CM240 RS08000
gene id: 1216932:CM240_RS08000
uniprot id: W6S384
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1216932:CM240 RS04840
gene id: 1216932:CM240_RS04840
uniprot id: W6S1H6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1216932:CM240 RS00340
gene id: 1216932:CM240_RS00340
uniprot id: W6RYY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1216932:CM240 RS01410
gene id: 1216932:CM240_RS01410
uniprot id: W6RZL9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11175
gene id: 1216932:CM240_RS11175
uniprot id: W6S516
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1216932:CM240 RS05120
gene id: 1216932:CM240_RS05120
uniprot id: W6SEU0
names: Similarity
messages: Belongs to the UPF0047 family.

1216932:CM240 RS03675
gene id: 1216932:CM240_RS03675
uniprot id: W6RUE3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1216932:CM240 RS03295
gene id: 1216932:CM240_RS03295
uniprot id: W6RT79
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1216932:CM240 RS07035
gene id: 1216932:CM240_RS07035
uniprot id: W6RW25
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1216932:CM240 RS04260
gene id: 1216932:CM240_RS04260
uniprot id: W6SEE8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1216932:CM240 RS02725
gene id: 1216932:CM240_RS02725
uniprot id: W6RVT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1216932:CM240 RS05950
gene id: 1216932:CM240_RS05950
uniprot id: W6S232
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS01425
gene id: 1216932:CM240_RS01425
uniprot id: W6SCY9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1216932:CM240 RS11315
gene id: 1216932:CM240_RS11315
uniprot id: W6SIF7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS01895
gene id: 1216932:CM240_RS01895
uniprot id: W6RSJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1216932:CM240 RS09135
gene id: 1216932:CM240_RS09135
uniprot id: W6RWE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS07345
gene id: 1216932:CM240_RS07345
uniprot id: W6SG16
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

1216932:CM240 RS01665
gene id: 1216932:CM240_RS01665
uniprot id: W6RV78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS10025
gene id: 1216932:CM240_RS10025
uniprot id: W6SHK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1216932:CM240 RS08740
gene id: 1216932:CM240_RS08740
uniprot id: W6RW85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1216932:CM240 RS12190
gene id: 1216932:CM240_RS12190
uniprot id: W6RYR4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1216932:CM240 RS07400
gene id: 1216932:CM240_RS07400
uniprot id: W6RVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1216932:CM240 RS08475
gene id: 1216932:CM240_RS08475
uniprot id: W6RWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1216932:CM240 RS14870
gene id: 1216932:CM240_RS14870
uniprot id: W6S2J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1216932:CM240 RS13215
gene id: 1216932:CM240_RS13215
uniprot id: W6RYR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1216932:CM240 RS04055
gene id: 1216932:CM240_RS04055
uniprot id: W6RWH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1216932:CM240 RS03780
gene id: 1216932:CM240_RS03780
uniprot id: W6RWD1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1216932:CM240 RS08925
gene id: 1216932:CM240_RS08925
uniprot id: W6RZD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1216932:CM240 RS10505
gene id: 1216932:CM240_RS10505
uniprot id: W6RXU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS02870
gene id: 1216932:CM240_RS02870
uniprot id: W6RTX5
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS06855
gene id: 1216932:CM240_RS06855
uniprot id: W6RY46
names: Similarity
messages: Belongs to the peptidase S14 family.

1216932:CM240 RS12695
gene id: 1216932:CM240_RS12695
uniprot id: W6SJ32
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1216932:CM240 RS12100
gene id: 1216932:CM240_RS12100
uniprot id: W6SIU0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1216932:CM240 RS12115
gene id: 1216932:CM240_RS12115
uniprot id: W6RYQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1216932:CM240 RS04905
gene id: 1216932:CM240_RS04905
uniprot id: W6SEQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1216932:CM240 RS10995
gene id: 1216932:CM240_RS10995
uniprot id: W6SI54
names: Similarity
messages: Belongs to the manganese catalase family.

1216932:CM240 RS10205
gene id: 1216932:CM240_RS10205
uniprot id: W6RX13
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1216932:CM240 RS00100
gene id: 1216932:CM240_RS00100
uniprot id: W6RSJ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS11420
gene id: 1216932:CM240_RS11420
uniprot id: W6RXR6
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1216932:CM240 RS08525
gene id: 1216932:CM240_RS08525
uniprot id: W6RWZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1216932:CM240 RS09230
gene id: 1216932:CM240_RS09230
uniprot id: W6SH72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS12160
gene id: 1216932:CM240_RS12160
uniprot id: W6S5G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1216932:CM240 RS05255
gene id: 1216932:CM240_RS05255
uniprot id: W6RV74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1216932:CM240 RS12195
gene id: 1216932:CM240_RS12195
uniprot id: W6S157
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1216932:CM240 RS05565
gene id: 1216932:CM240_RS05565
uniprot id: W6SF12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1216932:CM240 RS12900
gene id: 1216932:CM240_RS12900
uniprot id: W6SJ76
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS06505
gene id: 1216932:CM240_RS06505
uniprot id: W6RUY5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1216932:CM240 RS14310
gene id: 1216932:CM240_RS14310
uniprot id: W6RZX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS08750
gene id: 1216932:CM240_RS08750
uniprot id: W6RX39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1216932:CM240 RS08325
gene id: 1216932:CM240_RS08325
uniprot id: W6RWV0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1216932:CM240 RS05925
gene id: 1216932:CM240_RS05925
uniprot id: W6S226
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1216932:CM240 RS08755
gene id: 1216932:CM240_RS08755
uniprot id: W6RZB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1216932:CM240 RS06050
gene id: 1216932:CM240_RS06050
uniprot id: W6RVQ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1216932:CM240 RS09540
gene id: 1216932:CM240_RS09540
uniprot id: W6RXE0
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

1216932:CM240 RS11495
gene id: 1216932:CM240_RS11495
uniprot id: W6S559
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1216932:CM240 RS04835
gene id: 1216932:CM240_RS04835
uniprot id: W6RU57
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1216932:CM240 RS14725
gene id: 1216932:CM240_RS14725
uniprot id: W6S044
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1216932:CM240 RS08135
gene id: 1216932:CM240_RS08135
uniprot id: W6SGG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1216932:CM240 RS11300
gene id: 1216932:CM240_RS11300
uniprot id: W6S534
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1216932:CM240 RS12225
gene id: 1216932:CM240_RS12225
uniprot id: W6S162
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1216932:CM240 RS10695
gene id: 1216932:CM240_RS10695
uniprot id: W6RXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1216932:CM240 RS04185
gene id: 1216932:CM240_RS04185
uniprot id: W6SED8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS08970
gene id: 1216932:CM240_RS08970
uniprot id: W6RX68
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS11410
gene id: 1216932:CM240_RS11410
uniprot id: W6S0S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1216932:CM240 RS03805
gene id: 1216932:CM240_RS03805
uniprot id: W6RWD6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1216932:CM240 RS12505
gene id: 1216932:CM240_RS12505
uniprot id: W6SJ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

1216932:CM240 RS12210
gene id: 1216932:CM240_RS12210
uniprot id: W6RY66
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1216932:CM240 RS13280
gene id: 1216932:CM240_RS13280
uniprot id: W6S1P3
names: Similarity
messages: Belongs to the ParB family.

1216932:CM240 RS02835
gene id: 1216932:CM240_RS02835
uniprot id: W6RT00
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS07170
gene id: 1216932:CM240_RS07170
uniprot id: W6SFY2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1216932:CM240 RS04875
gene id: 1216932:CM240_RS04875
uniprot id: W6RWZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1216932:CM240 RS01675
gene id: 1216932:CM240_RS01675
uniprot id: W6RSF5
names: Similarity
messages: Belongs to the UPF0473 family.

1216932:CM240 RS06365
gene id: 1216932:CM240_RS06365
uniprot id: W6SFJ2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

1216932:CM240 RS10515
gene id: 1216932:CM240_RS10515
uniprot id: W6SHT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1216932:CM240 RS01935
gene id: 1216932:CM240_RS01935
uniprot id: W6RVD4
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11550
gene id: 1216932:CM240_RS11550
uniprot id: W6S0U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1216932:CM240 RS08370
gene id: 1216932:CM240_RS08370
uniprot id: W6S3F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1216932:CM240 RS10345
gene id: 1216932:CM240_RS10345
uniprot id: W6S4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1216932:CM240 RS15435
gene id: 1216932:CM240_RS15435
uniprot id: W6S0G8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1216932:CM240 RS04995
gene id: 1216932:CM240_RS04995
uniprot id: W6RX16
names: Similarity
messages: Belongs to the peptidase C40 family.

1216932:CM240 RS07905
gene id: 1216932:CM240_RS07905
uniprot id: W6RWL4
names: Similarity
messages: Belongs to the UPF0749 family.

1216932:CM240 RS13085
gene id: 1216932:CM240_RS13085
uniprot id: W6S5Z5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1216932:CM240 RS09530
gene id: 1216932:CM240_RS09530
uniprot id: W6RWM6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1216932:CM240 RS14415
gene id: 1216932:CM240_RS14415
uniprot id: W6S2B3
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS16475
gene id: 1216932:CM240_RS16475
uniprot id: W6SKN0
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1216932:CM240 RS11900
gene id: 1216932:CM240_RS11900
uniprot id: W6SIQ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1216932:CM240 RS03990
gene id: 1216932:CM240_RS03990
uniprot id: W6RTP9
names: Similarity
messages: Belongs to the RNase H family.

1216932:CM240 RS10955
gene id: 1216932:CM240_RS10955
uniprot id: W6RXG5
names: Subcellular Location Annotation
messages: Cell membrane

1216932:CM240 RS02600
gene id: 1216932:CM240_RS02600
uniprot id: W6RVR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1216932:CM240 RS12495
gene id: 1216932:CM240_RS12495
uniprot id: W6RYV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1216932:CM240 RS03700
gene id: 1216932:CM240_RS03700
uniprot id: W6RUE7
names: Similarity
messages: Belongs to the TrpF family.

1216932:CM240 RS10525
gene id: 1216932:CM240_RS10525
uniprot id: W6S4L0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1216932:CM240 RS09345
gene id: 1216932:CM240_RS09345
uniprot id: W6RXB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1216932:CM240 RS04925
gene id: 1216932:CM240_RS04925
uniprot id: W6RX02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1216932:CM240 RS00435
gene id: 1216932:CM240_RS00435
uniprot id: W6RZ10
names: Similarity
messages: Belongs to the leucine-binding protein family.

1216932:CM240 RS08410
gene id: 1216932:CM240_RS08410
uniprot id: W6SGM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1216932:CM240 RS09805
gene id: 1216932:CM240_RS09805
uniprot id: W6RWT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1216932:CM240 RS00390
gene id: 1216932:CM240_RS00390
uniprot id: W6RSN4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1216932:CM240 RS11655
gene id: 1216932:CM240_RS11655
uniprot id: W6RXW4
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1216932:CM240 RS14530
gene id: 1216932:CM240_RS14530
uniprot id: W6S010
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS03970
gene id: 1216932:CM240_RS03970
uniprot id: W6S107
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1216932:CM240 RS02220
gene id: 1216932:CM240_RS02220
uniprot id: W6RVI9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS13395
gene id: 1216932:CM240_RS13395
uniprot id: W6SJE9
names: Similarity
messages: Belongs to the peptidase S51 family.

1216932:CM240 RS06070
gene id: 1216932:CM240_RS06070
uniprot id: W6S294
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1216932:CM240 RS03705
gene id: 1216932:CM240_RS03705
uniprot id: W6RWC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1216932:CM240 RS10440
gene id: 1216932:CM240_RS10440
uniprot id: W6SHS6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1216932:CM240 RS15395
gene id: 1216932:CM240_RS15395
uniprot id: W6SK89
names: Similarity
messages: Belongs to the P(II) protein family.

1216932:CM240 RS09170
gene id: 1216932:CM240_RS09170
uniprot id: W6RX89
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1216932:CM240 RS14845
gene id: 1216932:CM240_RS14845
uniprot id: W6S2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS11985
gene id: 1216932:CM240_RS11985
uniprot id: W6S5D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1216932:CM240 RS03575
gene id: 1216932:CM240_RS03575
uniprot id: W6S0U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1216932:CM240 RS06045
gene id: 1216932:CM240_RS06045
uniprot id: W6S288
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1216932:CM240 RS07955
gene id: 1216932:CM240_RS07955
uniprot id: W6RWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1216932:CM240 RS07625
gene id: 1216932:CM240_RS07625
uniprot id: W6SG68
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1216932:CM240 RS03975
gene id: 1216932:CM240_RS03975
uniprot id: W6RUJ1
names: Similarity
messages: Belongs to the UPF0178 family.

1216932:CM240 RS13665
gene id: 1216932:CM240_RS13665
uniprot id: W6SJK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1216932:CM240 RS08075
gene id: 1216932:CM240_RS08075
uniprot id: W6RWQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1216932:CM240 RS15495
gene id: 1216932:CM240_RS15495
uniprot id: W6S027
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS03485
gene id: 1216932:CM240_RS03485
uniprot id: W6RW60
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1216932:CM240 RS00945
gene id: 1216932:CM240_RS00945
uniprot id: W6SCM8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS15115
gene id: 1216932:CM240_RS15115
uniprot id: W6RZU4
names: Similarity
messages: Belongs to the transpeptidase family.

1216932:CM240 RS15035
gene id: 1216932:CM240_RS15035
uniprot id: W6S2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1216932:CM240 RS08455
gene id: 1216932:CM240_RS08455
uniprot id: W6RZ26
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS11580
gene id: 1216932:CM240_RS11580
uniprot id: W6SIJ7
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

1216932:CM240 RS02540
gene id: 1216932:CM240_RS02540
uniprot id: W6S083
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1216932:CM240 RS04065
gene id: 1216932:CM240_RS04065
uniprot id: W6RTR1
names: Similarity
messages: Belongs to the NDK family.

1216932:CM240 RS03660
gene id: 1216932:CM240_RS03660
uniprot id: W6SE59
names: Similarity
messages: Belongs to the peptidase S11 family.

1216932:CM240 RS10730
gene id: 1216932:CM240_RS10730
uniprot id: W6S0D8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1216932:CM240 RS12030
gene id: 1216932:CM240_RS12030
uniprot id: W6RY33
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1216932:CM240 RS08895
gene id: 1216932:CM240_RS08895
uniprot id: W6RX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1216932:CM240 RS13300
gene id: 1216932:CM240_RS13300
uniprot id: W6RZ99
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS05055
gene id: 1216932:CM240_RS05055
uniprot id: W6RU95
names: Similarity
messages: Belongs to the barstar family.

1216932:CM240 RS01735
gene id: 1216932:CM240_RS01735
uniprot id: W6RTD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1216932:CM240 RS11280
gene id: 1216932:CM240_RS11280
uniprot id: W6RYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1216932:CM240 RS12540
gene id: 1216932:CM240_RS12540
uniprot id: W6S5N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1216932:CM240 RS05905
gene id: 1216932:CM240_RS05905
uniprot id: W6RVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1216932:CM240 RS10830
gene id: 1216932:CM240_RS10830
uniprot id: W6RXE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1216932:CM240 RS11990
gene id: 1216932:CM240_RS11990
uniprot id: W6RYN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1216932:CM240 RS07105
gene id: 1216932:CM240_RS07105
uniprot id: W6S2R3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1216932:CM240 RS09335
gene id: 1216932:CM240_RS09335
uniprot id: W6RWI6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS09010
gene id: 1216932:CM240_RS09010
uniprot id: W6RWC8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1216932:CM240 RS06480
gene id: 1216932:CM240_RS06480
uniprot id: W6RXY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1216932:CM240 RS03690
gene id: 1216932:CM240_RS03690
uniprot id: W6RTJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS08485
gene id: 1216932:CM240_RS08485
uniprot id: W6SGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1216932:CM240 RS03735
gene id: 1216932:CM240_RS03735
uniprot id: W6SE70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1216932:CM240 RS00770
gene id: 1216932:CM240_RS00770
uniprot id: W6RZ64
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1216932:CM240 RS13730
gene id: 1216932:CM240_RS13730
uniprot id: W6RZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1216932:CM240 RS05810
gene id: 1216932:CM240_RS05810
uniprot id: W6RXI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS17865
gene id: 1216932:CM240_RS17865
uniprot id: W6RZ58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1216932:CM240 RS14850
gene id: 1216932:CM240_RS14850
uniprot id: W6SK21
names: Similarity
messages: Belongs to the P(II) protein family.

1216932:CM240 RS01185
gene id: 1216932:CM240_RS01185
uniprot id: W6RZI3
names: Subcellular Location Annotation
messages: cell wall

1216932:CM240 RS00350
gene id: 1216932:CM240_RS00350
uniprot id: W6RUD5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1216932:CM240 RS05590
gene id: 1216932:CM240_RS05590
uniprot id: W6SF15
names: Similarity
messages: Belongs to the WXG100 family.

1216932:CM240 RS07455
gene id: 1216932:CM240_RS07455
uniprot id: W6S2Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1216932:CM240 RS07360
gene id: 1216932:CM240_RS07360
uniprot id: W6RW84
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS03630
gene id: 1216932:CM240_RS03630
uniprot id: W6RWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS11375
gene id: 1216932:CM240_RS11375
uniprot id: W6S542
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1216932:CM240 RS14740
gene id: 1216932:CM240_RS14740
uniprot id: W6RZL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS10185
gene id: 1216932:CM240_RS10185
uniprot id: W6S4E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1216932:CM240 RS07705
gene id: 1216932:CM240_RS07705
uniprot id: W6RVJ7
names: Similarity
messages: Belongs to the RecJ family.

1216932:CM240 RS13560
gene id: 1216932:CM240_RS13560
uniprot id: W6RZF1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1216932:CM240 RS04830
gene id: 1216932:CM240_RS04830
uniprot id: W6SEP7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS03520
gene id: 1216932:CM240_RS03520
uniprot id: W6RTD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS10485
gene id: 1216932:CM240_RS10485
uniprot id: W6S090
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1216932:CM240 RS03940
gene id: 1216932:CM240_RS03940
uniprot id: W6RTP1
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS03715
gene id: 1216932:CM240_RS03715
uniprot id: W6RTJ5
names: Similarity
messages: Belongs to the citrate synthase family.

1216932:CM240 RS11405
gene id: 1216932:CM240_RS11405
uniprot id: W6RYC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1216932:CM240 RS15465
gene id: 1216932:CM240_RS15465
uniprot id: W6SK99
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS06370
gene id: 1216932:CM240_RS06370
uniprot id: W6RUW4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1216932:CM240 RS11960
gene id: 1216932:CM240_RS11960
uniprot id: W6S5C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1216932:CM240 RS08495
gene id: 1216932:CM240_RS08495
uniprot id: W6S3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

1216932:CM240 RS07300
gene id: 1216932:CM240_RS07300
uniprot id: W6RVC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1216932:CM240 RS16635
gene id: 1216932:CM240_RS16635
uniprot id: W6SCJ0
names: Similarity
messages: Belongs to the peptidase C40 family.

1216932:CM240 RS09625
gene id: 1216932:CM240_RS09625
uniprot id: W6SHD6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1216932:CM240 RS07970
gene id: 1216932:CM240_RS07970
uniprot id: W6RVP3
names: Similarity
messages: Belongs to the peptidase S16 family.

1216932:CM240 RS05555
gene id: 1216932:CM240_RS05555
uniprot id: W6RVD5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1216932:CM240 RS00670
gene id: 1216932:CM240_RS00670
uniprot id: W6RZ49
names: Similarity
messages: Belongs to the UPF0229 family.

1216932:CM240 RS10130
gene id: 1216932:CM240_RS10130
uniprot id: W6RX00
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1216932:CM240 RS12545
gene id: 1216932:CM240_RS12545
uniprot id: W6RYW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS07460
gene id: 1216932:CM240_RS07460
uniprot id: W6RWB8
names: Similarity
messages: Belongs to the transpeptidase family.

1216932:CM240 RS05310
gene id: 1216932:CM240_RS05310
uniprot id: W6RX86
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1216932:CM240 RS08065
gene id: 1216932:CM240_RS08065
uniprot id: W6RVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1216932:CM240 RS12385
gene id: 1216932:CM240_RS12385
uniprot id: W6SIY6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1216932:CM240 RS05130
gene id: 1216932:CM240_RS05130
uniprot id: W6RV48
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1216932:CM240 RS08125
gene id: 1216932:CM240_RS08125
uniprot id: W6RWR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1216932:CM240 RS12125
gene id: 1216932:CM240_RS12125
uniprot id: W6SIU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1216932:CM240 RS07305
gene id: 1216932:CM240_RS07305
uniprot id: W6S2V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1216932:CM240 RS10885
gene id: 1216932:CM240_RS10885
uniprot id: W6S4S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS08665
gene id: 1216932:CM240_RS08665
uniprot id: W6RW76
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS14760
gene id: 1216932:CM240_RS14760
uniprot id: W6S6U0
names: Similarity
messages: Belongs to the YciI family.

1216932:CM240 RS08040
gene id: 1216932:CM240_RS08040
uniprot id: W6RVQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1216932:CM240 RS00065
gene id: 1216932:CM240_RS00065
uniprot id: W6RRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS06460
gene id: 1216932:CM240_RS06460
uniprot id: W6SFK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS09510
gene id: 1216932:CM240_RS09510
uniprot id: W6S430
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1216932:CM240 RS08955
gene id: 1216932:CM240_RS08955
uniprot id: W6SH26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS13240
gene id: 1216932:CM240_RS13240
uniprot id: W6RYS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1216932:CM240 RS05740
gene id: 1216932:CM240_RS05740
uniprot id: W6SF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS09660
gene id: 1216932:CM240_RS09660
uniprot id: W6S450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1216932:CM240 RS05680
gene id: 1216932:CM240_RS05680
uniprot id: W6RVG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1216932:CM240 RS09930
gene id: 1216932:CM240_RS09930
uniprot id: W6RWW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1216932:CM240 RS10700
gene id: 1216932:CM240_RS10700
uniprot id: W6S4P2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1216932:CM240 RS14155
gene id: 1216932:CM240_RS14155
uniprot id: W6RZB4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1216932:CM240 RS07110
gene id: 1216932:CM240_RS07110
uniprot id: W6RW37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS10890
gene id: 1216932:CM240_RS10890
uniprot id: W6RY05
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS01150
gene id: 1216932:CM240_RS01150
uniprot id: W6SCU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1216932:CM240 RS01585
gene id: 1216932:CM240_RS01585
uniprot id: W6RTA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1216932:CM240 RS06895
gene id: 1216932:CM240_RS06895
uniprot id: W6S2M5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1216932:CM240 RS05560
gene id: 1216932:CM240_RS05560
uniprot id: W6RXD8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1216932:CM240 RS03795
gene id: 1216932:CM240_RS03795
uniprot id: W6S0Y0
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS08070
gene id: 1216932:CM240_RS08070
uniprot id: W6S395
names: Similarity
messages: Belongs to the MotB family.

1216932:CM240 RS05445
gene id: 1216932:CM240_RS05445
uniprot id: W6RUE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1216932:CM240 RS10370
gene id: 1216932:CM240_RS10370
uniprot id: W6S4I1
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12555
gene id: 1216932:CM240_RS12555
uniprot id: W6SJ08
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1216932:CM240 RS01865
gene id: 1216932:CM240_RS01865
uniprot id: W6RVB9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS01145
gene id: 1216932:CM240_RS01145
uniprot id: W6RUY1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1216932:CM240 RS04240
gene id: 1216932:CM240_RS04240
uniprot id: W6RTU5
names: Similarity
messages: Belongs to the UPF0251 family.

1216932:CM240 RS09975
gene id: 1216932:CM240_RS09975
uniprot id: W6SHJ9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1216932:CM240 RS13435
gene id: 1216932:CM240_RS13435
uniprot id: W6RZC8
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS01035
gene id: 1216932:CM240_RS01035
uniprot id: W6RZE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1216932:CM240 RS00425
gene id: 1216932:CM240_RS00425
uniprot id: W6SCB3
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS09000
gene id: 1216932:CM240_RS09000
uniprot id: W6RZF0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1216932:CM240 RS02285
gene id: 1216932:CM240_RS02285
uniprot id: W6RVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1216932:CM240 RS00335
gene id: 1216932:CM240_RS00335
uniprot id: W6RRP3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS05450
gene id: 1216932:CM240_RS05450
uniprot id: W6S1U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1216932:CM240 RS08645
gene id: 1216932:CM240_RS08645
uniprot id: W6S3L5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1216932:CM240 RS05935
gene id: 1216932:CM240_RS05935
uniprot id: W6RXL0
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1216932:CM240 RS10735
gene id: 1216932:CM240_RS10735
uniprot id: W6SHX5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1216932:CM240 RS09580
gene id: 1216932:CM240_RS09580
uniprot id: W6RWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS13115
gene id: 1216932:CM240_RS13115
uniprot id: W6RZ69
names: Similarity
messages: Belongs to the CinA family.

1216932:CM240 RS08775
gene id: 1216932:CM240_RS08775
uniprot id: W6RX41
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12285
gene id: 1216932:CM240_RS12285
uniprot id: W6S5J6
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11605
gene id: 1216932:CM240_RS11605
uniprot id: W6RXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS07710
gene id: 1216932:CM240_RS07710
uniprot id: W6S334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1216932:CM240 RS06525
gene id: 1216932:CM240_RS06525
uniprot id: W6SFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1216932:CM240 RS10070
gene id: 1216932:CM240_RS10070
uniprot id: W6S005
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1216932:CM240 RS05765
gene id: 1216932:CM240_RS05765
uniprot id: W6SF49
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1216932:CM240 RS02900
gene id: 1216932:CM240_RS02900
uniprot id: W6RVW5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1216932:CM240 RS11305
gene id: 1216932:CM240_RS11305
uniprot id: W6RYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1216932:CM240 RS09175
gene id: 1216932:CM240_RS09175
uniprot id: W6RZH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1216932:CM240 RS02265
gene id: 1216932:CM240_RS02265
uniprot id: W6RTL0
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS07190
gene id: 1216932:CM240_RS07190
uniprot id: W6RYA3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1216932:CM240 RS12045
gene id: 1216932:CM240_RS12045
uniprot id: W6S130
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1216932:CM240 RS00595
gene id: 1216932:CM240_RS00595
uniprot id: W6SCF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS08055
gene id: 1216932:CM240_RS08055
uniprot id: W6RYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1216932:CM240 RS14285
gene id: 1216932:CM240_RS14285
uniprot id: W6S6K7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1216932:CM240 RS05525
gene id: 1216932:CM240_RS05525
uniprot id: W6S1V7
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS09840
gene id: 1216932:CM240_RS09840
uniprot id: W6RXH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1216932:CM240 RS01690
gene id: 1216932:CM240_RS01690
uniprot id: W6RV83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1216932:CM240 RS17600
gene id: 1216932:CM240_RS17600
uniprot id: W6RZ41
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1216932:CM240 RS06780
gene id: 1216932:CM240_RS06780
uniprot id: W6RV35
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS04280
gene id: 1216932:CM240_RS04280
uniprot id: W6SEF4
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1216932:CM240 RS07135
gene id: 1216932:CM240_RS07135
uniprot id: W6RW42
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS00960
gene id: 1216932:CM240_RS00960
uniprot id: W6RSZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS12085
gene id: 1216932:CM240_RS12085
uniprot id: W6S5F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1216932:CM240 RS09585
gene id: 1216932:CM240_RS09585
uniprot id: W6S442
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1216932:CM240 RS04965
gene id: 1216932:CM240_RS04965
uniprot id: W6RV16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1216932:CM240 RS02390
gene id: 1216932:CM240_RS02390
uniprot id: W6RSS3
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1216932:CM240 RS06055
gene id: 1216932:CM240_RS06055
uniprot id: W6RXS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1216932:CM240 RS10640
gene id: 1216932:CM240_RS10640
uniprot id: W6SHV6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1216932:CM240 RS16175
gene id: 1216932:CM240_RS16175
uniprot id: W6S110
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1216932:CM240 RS07155
gene id: 1216932:CM240_RS07155
uniprot id: W6S2S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS06635
gene id: 1216932:CM240_RS06635
uniprot id: W6RVX5
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

1216932:CM240 RS10740
gene id: 1216932:CM240_RS10740
uniprot id: W6RXD5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1216932:CM240 RS15060
gene id: 1216932:CM240_RS15060
uniprot id: W6S2N7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS08660
gene id: 1216932:CM240_RS08660
uniprot id: W6SGX8
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS00225
gene id: 1216932:CM240_RS00225
uniprot id: W6RYX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1216932:CM240 RS13305
gene id: 1216932:CM240_RS13305
uniprot id: W6S1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1216932:CM240 RS07180
gene id: 1216932:CM240_RS07180
uniprot id: W6S2S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1216932:CM240 RS04740
gene id: 1216932:CM240_RS04740
uniprot id: W6S1F7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1216932:CM240 RS12600
gene id: 1216932:CM240_RS12600
uniprot id: W6RYX1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1216932:CM240 RS09865
gene id: 1216932:CM240_RS09865
uniprot id: W6RXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS07940
gene id: 1216932:CM240_RS07940
uniprot id: W6SGC3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS05975
gene id: 1216932:CM240_RS05975
uniprot id: W6S238
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1216932:CM240 RS09920
gene id: 1216932:CM240_RS09920
uniprot id: W6RZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS01430
gene id: 1216932:CM240_RS01430
uniprot id: W6RSB2
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1216932:CM240 RS05025
gene id: 1216932:CM240_RS05025
uniprot id: W6SES4
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

1216932:CM240 RS04355
gene id: 1216932:CM240_RS04355
uniprot id: W6SEG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1216932:CM240 RS06970
gene id: 1216932:CM240_RS06970
uniprot id: W6S2N8
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1216932:CM240 RS00745
gene id: 1216932:CM240_RS00745
uniprot id: W6RZ59
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1216932:CM240 RS08465
gene id: 1216932:CM240_RS08465
uniprot id: W6RVZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1216932:CM240 RS00185
gene id: 1216932:CM240_RS00185
uniprot id: W6RRM2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1216932:CM240 RS10510
gene id: 1216932:CM240_RS10510
uniprot id: W6S095
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1216932:CM240 RS04715
gene id: 1216932:CM240_RS04715
uniprot id: W6S1F2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1216932:CM240 RS07690
gene id: 1216932:CM240_RS07690
uniprot id: W6RWG5
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1216932:CM240 RS02555
gene id: 1216932:CM240_RS02555
uniprot id: W6SDG4
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS15130
gene id: 1216932:CM240_RS15130
uniprot id: W6SK51
names: Similarity
messages: Belongs to the EamA transporter family.

1216932:CM240 RS08545
gene id: 1216932:CM240_RS08545
uniprot id: W6S3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1216932:CM240 RS03960
gene id: 1216932:CM240_RS03960
uniprot id: W6SEA5
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1216932:CM240 RS07590
gene id: 1216932:CM240_RS07590
uniprot id: W6RWE5
names: Similarity
messages: Belongs to the peptidase S11 family.

1216932:CM240 RS03665
gene id: 1216932:CM240_RS03665
uniprot id: W6RTI8
names: Similarity
messages: Belongs to the NDK family.

1216932:CM240 RS03475
gene id: 1216932:CM240_RS03475
uniprot id: W6S0Q6
names: Similarity
messages: Belongs to the ThiD family.

1216932:CM240 RS08530
gene id: 1216932:CM240_RS08530
uniprot id: W6RZ55
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1216932:CM240 RS08045
gene id: 1216932:CM240_RS08045
uniprot id: W6S391
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1216932:CM240 RS02445
gene id: 1216932:CM240_RS02445
uniprot id: W6RTQ0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS08630
gene id: 1216932:CM240_RS08630
uniprot id: W6RZ89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1216932:CM240 RS06660
gene id: 1216932:CM240_RS06660
uniprot id: W6RVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1216932:CM240 RS08305
gene id: 1216932:CM240_RS08305
uniprot id: W6RYZ6
names: Similarity
messages: Belongs to the bacterial flagellin family.

1216932:CM240 RS12020
gene id: 1216932:CM240_RS12020
uniprot id: W6S124
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1216932:CM240 RS09785
gene id: 1216932:CM240_RS09785
uniprot id: W6S472
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1216932:CM240 RS01520
gene id: 1216932:CM240_RS01520
uniprot id: W6SD03
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1216932:CM240 RS09450
gene id: 1216932:CM240_RS09450
uniprot id: W6SHA7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1216932:CM240 RS03930
gene id: 1216932:CM240_RS03930
uniprot id: W6SEA2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1216932:CM240 RS07285
gene id: 1216932:CM240_RS07285
uniprot id: W6RW64
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1216932:CM240 RS07740
gene id: 1216932:CM240_RS07740
uniprot id: W6RYM9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1216932:CM240 RS12660
gene id: 1216932:CM240_RS12660
uniprot id: W6RYY7
names: Similarity
messages: Belongs to the ComB family.

1216932:CM240 RS06080
gene id: 1216932:CM240_RS06080
uniprot id: W6RXT1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1216932:CM240 RS01580
gene id: 1216932:CM240_RS01580
uniprot id: W6RZQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1216932:CM240 RS09770
gene id: 1216932:CM240_RS09770
uniprot id: W6RZU1
names: Similarity
messages: Belongs to the threonine synthase family.

1216932:CM240 RS06615
gene id: 1216932:CM240_RS06615
uniprot id: W6RY09
names: Similarity
messages: Belongs to the GSP E family.

1216932:CM240 RS14650
gene id: 1216932:CM240_RS14650
uniprot id: W6S031
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1216932:CM240 RS12135
gene id: 1216932:CM240_RS12135
uniprot id: W6S5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1216932:CM240 RS05715
gene id: 1216932:CM240_RS05715
uniprot id: W6SF41
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1216932:CM240 RS14770
gene id: 1216932:CM240_RS14770
uniprot id: W6S2H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1216932:CM240 RS00320
gene id: 1216932:CM240_RS00320
uniprot id: W6RSM0
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS05770
gene id: 1216932:CM240_RS05770
uniprot id: W6RUK1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1216932:CM240 RS02260
gene id: 1216932:CM240_RS02260
uniprot id: W6S029
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1216932:CM240 RS15960
gene id: 1216932:CM240_RS15960
uniprot id: W6S0B7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS09680
gene id: 1216932:CM240_RS09680
uniprot id: W6RWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1216932:CM240 RS07635
gene id: 1216932:CM240_RS07635
uniprot id: W6S319
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS04385
gene id: 1216932:CM240_RS04385
uniprot id: W6RTX2
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS10215
gene id: 1216932:CM240_RS10215
uniprot id: W6RXN9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS02205
gene id: 1216932:CM240_RS02205
uniprot id: W6RSN7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS12000
gene id: 1216932:CM240_RS12000
uniprot id: W6SIS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1216932:CM240 RS09365
gene id: 1216932:CM240_RS09365
uniprot id: W6RXB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1216932:CM240 RS09570
gene id: 1216932:CM240_RS09570
uniprot id: W6RZQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1216932:CM240 RS11180
gene id: 1216932:CM240_RS11180
uniprot id: W6RY91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1216932:CM240 RS07165
gene id: 1216932:CM240_RS07165
uniprot id: W6RY97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1216932:CM240 RS08245
gene id: 1216932:CM240_RS08245
uniprot id: W6S3C4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1216932:CM240 RS02950
gene id: 1216932:CM240_RS02950
uniprot id: W6RTZ2
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1216932:CM240 RS07860
gene id: 1216932:CM240_RS07860
uniprot id: W6RYQ6
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1216932:CM240 RS00345
gene id: 1216932:CM240_RS00345
uniprot id: W6RSM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1216932:CM240 RS05980
gene id: 1216932:CM240_RS05980
uniprot id: W6RVM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1216932:CM240 RS01705
gene id: 1216932:CM240_RS01705
uniprot id: W6RZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1216932:CM240 RS02385
gene id: 1216932:CM240_RS02385
uniprot id: W6SDD4
names: Similarity
messages: Belongs to the CobH/CbiC family.

1216932:CM240 RS02700
gene id: 1216932:CM240_RS02700
uniprot id: W6RVT5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1216932:CM240 RS07580
gene id: 1216932:CM240_RS07580
uniprot id: W6RVH3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1216932:CM240 RS07735
gene id: 1216932:CM240_RS07735
uniprot id: W6S338
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12090
gene id: 1216932:CM240_RS12090
uniprot id: W6RYP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1216932:CM240 RS13295
gene id: 1216932:CM240_RS13295
uniprot id: W6S624
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS01015
gene id: 1216932:CM240_RS01015
uniprot id: W6RT05
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1216932:CM240 RS09055
gene id: 1216932:CM240_RS09055
uniprot id: W6SH43
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1216932:CM240 RS11885
gene id: 1216932:CM240_RS11885
uniprot id: W6S5B5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1216932:CM240 RS01295
gene id: 1216932:CM240_RS01295
uniprot id: W6SCW8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1216932:CM240 RS01370
gene id: 1216932:CM240_RS01370
uniprot id: W6RV20
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS17090
gene id: 1216932:CM240_RS17090
uniprot id: W6S7U4
names: Similarity
messages: Belongs to the peptidase S8 family.

1216932:CM240 RS02545
gene id: 1216932:CM240_RS02545
uniprot id: W6RTR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1216932:CM240 RS13220
gene id: 1216932:CM240_RS13220
uniprot id: W6S612
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1216932:CM240 RS08680
gene id: 1216932:CM240_RS08680
uniprot id: W6RZ98
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS14815
gene id: 1216932:CM240_RS14815
uniprot id: W6S063
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS07615
gene id: 1216932:CM240_RS07615
uniprot id: W6RWF0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1216932:CM240 RS05115
gene id: 1216932:CM240_RS05115
uniprot id: W6RX43
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1216932:CM240 RS11685
gene id: 1216932:CM240_RS11685
uniprot id: W6S583
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1216932:CM240 RS10145
gene id: 1216932:CM240_RS10145
uniprot id: W6S021
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1216932:CM240 RS03115
gene id: 1216932:CM240_RS03115
uniprot id: W6SDR8
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12990
gene id: 1216932:CM240_RS12990
uniprot id: W6RZ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS04920
gene id: 1216932:CM240_RS04920
uniprot id: W6RV06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1216932:CM240 RS08435
gene id: 1216932:CM240_RS08435
uniprot id: W6SGM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1216932:CM240 RS16720
gene id: 1216932:CM240_RS16720
uniprot id: W6RUH9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1216932:CM240 RS11520
gene id: 1216932:CM240_RS11520
uniprot id: W6RYE7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS00680
gene id: 1216932:CM240_RS00680
uniprot id: W6RUL9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1216932:CM240 RS11435
gene id: 1216932:CM240_RS11435
uniprot id: W6SIH6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1216932:CM240 RS10480
gene id: 1216932:CM240_RS10480
uniprot id: W6RXT7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1216932:CM240 RS12235
gene id: 1216932:CM240_RS12235
uniprot id: W6RY70
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1216932:CM240 RS13040
gene id: 1216932:CM240_RS13040
uniprot id: W6RZ54
names: Similarity
messages: Belongs to the peptidase S8 family.

1216932:CM240 RS10585
gene id: 1216932:CM240_RS10585
uniprot id: W6S0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1216932:CM240 RS10015
gene id: 1216932:CM240_RS10015
uniprot id: W6RXK6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS03470
gene id: 1216932:CM240_RS03470
uniprot id: W6RTC1
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1216932:CM240 RS03525
gene id: 1216932:CM240_RS03525
uniprot id: W6S0R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1216932:CM240 RS07895
gene id: 1216932:CM240_RS07895
uniprot id: W6RVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1216932:CM240 RS10100
gene id: 1216932:CM240_RS10100
uniprot id: W6SHL6
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1216932:CM240 RS03615
gene id: 1216932:CM240_RS03615
uniprot id: W6RTI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1216932:CM240 RS01990
gene id: 1216932:CM240_RS01990
uniprot id: W6SD64
names: Similarity
messages: Belongs to the YjdM family.

1216932:CM240 RS01960
gene id: 1216932:CM240_RS01960
uniprot id: W6RVD7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS13270
gene id: 1216932:CM240_RS13270
uniprot id: W6S619
names: Similarity
messages: Belongs to the ParB family.

1216932:CM240 RS09675
gene id: 1216932:CM240_RS09675
uniprot id: W6SHE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1216932:CM240 RS10625
gene id: 1216932:CM240_RS10625
uniprot id: W6S4M9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1216932:CM240 RS01490
gene id: 1216932:CM240_RS01490
uniprot id: W6RT91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1216932:CM240 RS14955
gene id: 1216932:CM240_RS14955
uniprot id: W6S089
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS12970
gene id: 1216932:CM240_RS12970
uniprot id: W6S1J1
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS10545
gene id: 1216932:CM240_RS10545
uniprot id: W6RX88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1216932:CM240 RS11770
gene id: 1216932:CM240_RS11770
uniprot id: W6S0Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1216932:CM240 RS11810
gene id: 1216932:CM240_RS11810
uniprot id: W6S5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1216932:CM240 RS12515
gene id: 1216932:CM240_RS12515
uniprot id: W6S5N1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS14700
gene id: 1216932:CM240_RS14700
uniprot id: W6S040
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1216932:CM240 RS08900
gene id: 1216932:CM240_RS08900
uniprot id: W6RZD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1216932:CM240 RS13020
gene id: 1216932:CM240_RS13020
uniprot id: W6S1K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS01715
gene id: 1216932:CM240_RS01715
uniprot id: W6RV90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1216932:CM240 RS03785
gene id: 1216932:CM240_RS03785
uniprot id: W6SE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1216932:CM240 RS15380
gene id: 1216932:CM240_RS15380
uniprot id: W6S750
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1216932:CM240 RS07790
gene id: 1216932:CM240_RS07790
uniprot id: W6RYP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1216932:CM240 RS09485
gene id: 1216932:CM240_RS09485
uniprot id: W6S426
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1216932:CM240 RS06015
gene id: 1216932:CM240_RS06015
uniprot id: W6RUR6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1216932:CM240 RS03290
gene id: 1216932:CM240_RS03290
uniprot id: W6SDU9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1216932:CM240 RS00230
gene id: 1216932:CM240_RS00230
uniprot id: W6RSL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1216932:CM240 RS04360
gene id: 1216932:CM240_RS04360
uniprot id: W6RTW6
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS08725
gene id: 1216932:CM240_RS08725
uniprot id: W6RX34
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1216932:CM240 RS12265
gene id: 1216932:CM240_RS12265
uniprot id: W6S5J2
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS05875
gene id: 1216932:CM240_RS05875
uniprot id: W6S215
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11380
gene id: 1216932:CM240_RS11380
uniprot id: W6RYB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1216932:CM240 RS12920
gene id: 1216932:CM240_RS12920
uniprot id: W6RZ34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS04310
gene id: 1216932:CM240_RS04310
uniprot id: W6RTV8
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1216932:CM240 RS00005
gene id: 1216932:CM240_RS00005
uniprot id: W6RU88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1216932:CM240 RS08350
gene id: 1216932:CM240_RS08350
uniprot id: W6RWV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1216932:CM240 RS10030
gene id: 1216932:CM240_RS10030
uniprot id: W6RWY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1216932:CM240 RS06685
gene id: 1216932:CM240_RS06685
uniprot id: W6RVY1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1216932:CM240 RS11115
gene id: 1216932:CM240_RS11115
uniprot id: W6RXM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1216932:CM240 RS08730
gene id: 1216932:CM240_RS08730
uniprot id: W6RZA8
names: Similarity
messages: Belongs to the peptidase C59 family.

1216932:CM240 RS07850
gene id: 1216932:CM240_RS07850
uniprot id: W6S362
names: Similarity
messages: Belongs to the GerABKA family.

1216932:CM240 RS11790
gene id: 1216932:CM240_RS11790
uniprot id: W6RYJ8
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1216932:CM240 RS08365
gene id: 1216932:CM240_RS08365
uniprot id: W6RVX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1216932:CM240 RS08275
gene id: 1216932:CM240_RS08275
uniprot id: W6RWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1216932:CM240 RS05910
gene id: 1216932:CM240_RS05910
uniprot id: W6RXK5
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1216932:CM240 RS08810
gene id: 1216932:CM240_RS08810
uniprot id: W6SH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS09970
gene id: 1216932:CM240_RS09970
uniprot id: W6RZY5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1216932:CM240 RS01200
gene id: 1216932:CM240_RS01200
uniprot id: W6SCV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1216932:CM240 RS12255
gene id: 1216932:CM240_RS12255
uniprot id: W6SIW6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1216932:CM240 RS12240
gene id: 1216932:CM240_RS12240
uniprot id: W6S5I6
names: Similarity
messages: Belongs to the ycf81 family.

1216932:CM240 RS13090
gene id: 1216932:CM240_RS13090
uniprot id: W6RZ63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1216932:CM240 RS04675
gene id: 1216932:CM240_RS04675
uniprot id: W6RUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1216932:CM240 RS12010
gene id: 1216932:CM240_RS12010
uniprot id: W6S5D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1216932:CM240 RS17990
gene id: 1216932:CM240_RS17990
uniprot id: W6S343
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1216932:CM240 RS05660
gene id: 1216932:CM240_RS05660
uniprot id: W6RXF4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1216932:CM240 RS07935
gene id: 1216932:CM240_RS07935
uniprot id: W6RYS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1216932:CM240 RS12410
gene id: 1216932:CM240_RS12410
uniprot id: W6SIZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1216932:CM240 RS13760
gene id: 1216932:CM240_RS13760
uniprot id: W6S202
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS00235
gene id: 1216932:CM240_RS00235
uniprot id: W6RUB9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1216932:CM240 RS14100
gene id: 1216932:CM240_RS14100
uniprot id: W6SJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1216932:CM240 RS13430
gene id: 1216932:CM240_RS13430
uniprot id: W6S647
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1216932:CM240 RS07610
gene id: 1216932:CM240_RS07610
uniprot id: W6S317
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1216932:CM240 RS12035
gene id: 1216932:CM240_RS12035
uniprot id: W6S5E0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1216932:CM240 RS10935
gene id: 1216932:CM240_RS10935
uniprot id: W6S4T1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1216932:CM240 RS10725
gene id: 1216932:CM240_RS10725
uniprot id: W6RXY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1216932:CM240 RS10600
gene id: 1216932:CM240_RS10600
uniprot id: W6S4M4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1216932:CM240 RS11970
gene id: 1216932:CM240_RS11970
uniprot id: W6S115
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1216932:CM240 RS12550
gene id: 1216932:CM240_RS12550
uniprot id: W6S1B4
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1216932:CM240 RS09765
gene id: 1216932:CM240_RS09765
uniprot id: W6RXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1216932:CM240 RS16765
gene id: 1216932:CM240_RS16765
uniprot id: W6SES7
names: Similarity
messages: Belongs to the prespore-cell-inducing factor family.

1216932:CM240 RS01475
gene id: 1216932:CM240_RS01475
uniprot id: W6SCZ6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1216932:CM240 RS00200
gene id: 1216932:CM240_RS00200
uniprot id: W6RSK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1216932:CM240 RS15850
gene id: 1216932:CM240_RS15850
uniprot id: W6S345
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS00955
gene id: 1216932:CM240_RS00955
uniprot id: W6RZA5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1216932:CM240 RS07480
gene id: 1216932:CM240_RS07480
uniprot id: W6S2Y9
names: Similarity
messages: Belongs to the UPF0758 family.

1216932:CM240 RS00815
gene id: 1216932:CM240_RS00815
uniprot id: W6RRX9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS11935
gene id: 1216932:CM240_RS11935
uniprot id: W6S5C4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS09520
gene id: 1216932:CM240_RS09520
uniprot id: W6RZN9
names: Similarity
messages: Belongs to the RemA family.

1216932:CM240 RS01695
gene id: 1216932:CM240_RS01695
uniprot id: W6SD23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1216932:CM240 RS11365
gene id: 1216932:CM240_RS11365
uniprot id: W6SIG2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1216932:CM240 RS08225
gene id: 1216932:CM240_RS08225
uniprot id: W6RWT3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1216932:CM240 RS01280
gene id: 1216932:CM240_RS01280
uniprot id: W6RZJ8
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS08460
gene id: 1216932:CM240_RS08460
uniprot id: W6SGN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1216932:CM240 RS09690
gene id: 1216932:CM240_RS09690
uniprot id: W6RXF7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1216932:CM240 RS12520
gene id: 1216932:CM240_RS12520
uniprot id: W6RYV9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1216932:CM240 RS01540
gene id: 1216932:CM240_RS01540
uniprot id: W6RV57
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS09080
gene id: 1216932:CM240_RS09080
uniprot id: W6SH47
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS02105
gene id: 1216932:CM240_RS02105
uniprot id: W6RTI6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS00465
gene id: 1216932:CM240_RS00465
uniprot id: W6RSQ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1216932:CM240 RS14525
gene id: 1216932:CM240_RS14525
uniprot id: W6S6P7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS00360
gene id: 1216932:CM240_RS00360
uniprot id: W6RRP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1216932:CM240 RS07680
gene id: 1216932:CM240_RS07680
uniprot id: W6RVJ2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS11850
gene id: 1216932:CM240_RS11850
uniprot id: W6SIP6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1216932:CM240 RS08265
gene id: 1216932:CM240_RS08265
uniprot id: W6RVV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1216932:CM240 RS06650
gene id: 1216932:CM240_RS06650
uniprot id: W6RV13
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1216932:CM240 RS11430
gene id: 1216932:CM240_RS11430
uniprot id: W6RYC9
names: Similarity
messages: Belongs to the GerABKA family.

1216932:CM240 RS11980
gene id: 1216932:CM240_RS11980
uniprot id: W6RY22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1216932:CM240 RS10200
gene id: 1216932:CM240_RS10200
uniprot id: W6SHN4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1216932:CM240 RS02065
gene id: 1216932:CM240_RS02065
uniprot id: W6SD75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1216932:CM240 RS08985
gene id: 1216932:CM240_RS08985
uniprot id: W6RWC5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1216932:CM240 RS10825
gene id: 1216932:CM240_RS10825
uniprot id: W6SHY3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1216932:CM240 RS09260
gene id: 1216932:CM240_RS09260
uniprot id: W6RWH2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1216932:CM240 RS08560
gene id: 1216932:CM240_RS08560
uniprot id: W6SGW0
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1216932:CM240 RS08765
gene id: 1216932:CM240_RS08765
uniprot id: W6RW88
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1216932:CM240 RS08295
gene id: 1216932:CM240_RS08295
uniprot id: W6S3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1216932:CM240 RS13320
gene id: 1216932:CM240_RS13320
uniprot id: W6RYT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1216932:CM240 RS16185
gene id: 1216932:CM240_RS16185
uniprot id: W6SKJ9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS17995
gene id: 1216932:CM240_RS17995
uniprot id: W6RWI4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1216932:CM240 RS15840
gene id: 1216932:CM240_RS15840
uniprot id: W6S7E4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1216932:CM240 RS07965
gene id: 1216932:CM240_RS07965
uniprot id: W6SGC8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1216932:CM240 RS12940
gene id: 1216932:CM240_RS12940
uniprot id: W6RZ38
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS11950
gene id: 1216932:CM240_RS11950
uniprot id: W6SIR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS05230
gene id: 1216932:CM240_RS05230
uniprot id: W6RV68
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1216932:CM240 RS00020
gene id: 1216932:CM240_RS00020
uniprot id: W6RYU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1216932:CM240 RS12825
gene id: 1216932:CM240_RS12825
uniprot id: W6SJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1216932:CM240 RS04580
gene id: 1216932:CM240_RS04580
uniprot id: W6RWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS03710
gene id: 1216932:CM240_RS03710
uniprot id: W6SE67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1216932:CM240 RS12120
gene id: 1216932:CM240_RS12120
uniprot id: W6S140
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1216932:CM240 RS03980
gene id: 1216932:CM240_RS03980
uniprot id: W6RWG2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1216932:CM240 RS07925
gene id: 1216932:CM240_RS07925
uniprot id: W6S372
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS12620
gene id: 1216932:CM240_RS12620
uniprot id: W6S1C5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1216932:CM240 RS09250
gene id: 1216932:CM240_RS09250
uniprot id: W6RZI9
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS03635
gene id: 1216932:CM240_RS03635
uniprot id: W6SE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1216932:CM240 RS13205
gene id: 1216932:CM240_RS13205
uniprot id: W6S1N0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1216932:CM240 RS14805
gene id: 1216932:CM240_RS14805
uniprot id: W6RZM7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1216932:CM240 RS03680
gene id: 1216932:CM240_RS03680
uniprot id: W6RWB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1216932:CM240 RS09965
gene id: 1216932:CM240_RS09965
uniprot id: W6RXJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1216932:CM240 RS03195
gene id: 1216932:CM240_RS03195
uniprot id: W6RT54
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1216932:CM240 RS12175
gene id: 1216932:CM240_RS12175
uniprot id: W6SIV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1216932:CM240 RS14615
gene id: 1216932:CM240_RS14615
uniprot id: W6RZJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1216932:CM240 RS01775
gene id: 1216932:CM240_RS01775
uniprot id: W6RSH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1216932:CM240 RS04530
gene id: 1216932:CM240_RS04530
uniprot id: W6RUT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS15075
gene id: 1216932:CM240_RS15075
uniprot id: W6S0A7
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

1216932:CM240 RS01195
gene id: 1216932:CM240_RS01195
uniprot id: W6RUZ1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 8 family.

1216932:CM240 RS12015
gene id: 1216932:CM240_RS12015
uniprot id: W6RYN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1216932:CM240 RS01220
gene id: 1216932:CM240_RS01220
uniprot id: W6SCV7
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS16970
gene id: 1216932:CM240_RS16970
uniprot id: W6S6A5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1216932:CM240 RS09500
gene id: 1216932:CM240_RS09500
uniprot id: W6SHB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1216932:CM240 RS08140
gene id: 1216932:CM240_RS08140
uniprot id: W6RVS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1216932:CM240 RS08540
gene id: 1216932:CM240_RS08540
uniprot id: W6RW56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1216932:CM240 RS11920
gene id: 1216932:CM240_RS11920
uniprot id: W6S106
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1216932:CM240 RS11995
gene id: 1216932:CM240_RS11995
uniprot id: W6S120
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1216932:CM240 RS06900
gene id: 1216932:CM240_RS06900
uniprot id: W6RW03
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1216932:CM240 RS03335
gene id: 1216932:CM240_RS03335
uniprot id: W6RW33
names: Similarity
messages: Belongs to the peptidase S14 family.

1216932:CM240 RS08340
gene id: 1216932:CM240_RS08340
uniprot id: W6RVX1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1216932:CM240 RS00165
gene id: 1216932:CM240_RS00165
uniprot id: W6RYW2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1216932:CM240 RS15805
gene id: 1216932:CM240_RS15805
uniprot id: W6SKE2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1216932:CM240 RS01600
gene id: 1216932:CM240_RS01600
uniprot id: W6RSE5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1216932:CM240 RS09855
gene id: 1216932:CM240_RS09855
uniprot id: W6RWU5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1216932:CM240 RS15875
gene id: 1216932:CM240_RS15875
uniprot id: W6S0Q3
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1216932:CM240 RS11145
gene id: 1216932:CM240_RS11145
uniprot id: W6RXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1216932:CM240 RS14560
gene id: 1216932:CM240_RS14560
uniprot id: W6S2D6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1216932:CM240 RS14680
gene id: 1216932:CM240_RS14680
uniprot id: W6S2F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS12820
gene id: 1216932:CM240_RS12820
uniprot id: W6S1G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1216932:CM240 RS13230
gene id: 1216932:CM240_RS13230
uniprot id: W6S1N5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1216932:CM240 RS08335
gene id: 1216932:CM240_RS08335
uniprot id: W6SGK5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1216932:CM240 RS11560
gene id: 1216932:CM240_RS11560
uniprot id: W6RXU4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1216932:CM240 RS02125
gene id: 1216932:CM240_RS02125
uniprot id: W6S004
names: Similarity
messages: Belongs to the UPF0246 family.

1216932:CM240 RS09290
gene id: 1216932:CM240_RS09290
uniprot id: W6S3Y9
names: Similarity
messages: Belongs to the glutamate synthase family.

1216932:CM240 RS07930
gene id: 1216932:CM240_RS07930
uniprot id: W6RWL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS02025
gene id: 1216932:CM240_RS02025
uniprot id: W6RZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1216932:CM240 RS13245
gene id: 1216932:CM240_RS13245
uniprot id: W6S615
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1216932:CM240 RS13790
gene id: 1216932:CM240_RS13790
uniprot id: W6SJN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1216932:CM240 RS11160
gene id: 1216932:CM240_RS11160
uniprot id: W6S0P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1216932:CM240 RS02515
gene id: 1216932:CM240_RS02515
uniprot id: W6S079
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1216932:CM240 RS02730
gene id: 1216932:CM240_RS02730
uniprot id: W6SDJ0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1216932:CM240 RS07550
gene id: 1216932:CM240_RS07550
uniprot id: W6SG53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1216932:CM240 RS00035
gene id: 1216932:CM240_RS00035
uniprot id: W6SC54
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1216932:CM240 RS16560
gene id: 1216932:CM240_RS16560
uniprot id: W6S181
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1216932:CM240 RS11295
gene id: 1216932:CM240_RS11295
uniprot id: W6RXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1216932:CM240 RS14145
gene id: 1216932:CM240_RS14145
uniprot id: W6S267
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1216932:CM240 RS10115
gene id: 1216932:CM240_RS10115
uniprot id: W6RXM4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1216932:CM240 RS00430
gene id: 1216932:CM240_RS00430
uniprot id: W6RRR0
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS13590
gene id: 1216932:CM240_RS13590
uniprot id: W6S1U6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1216932:CM240 RS05425
gene id: 1216932:CM240_RS05425
uniprot id: W6S1U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1216932:CM240 RS15670
gene id: 1216932:CM240_RS15670
uniprot id: W6S0L2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1216932:CM240 RS15040
gene id: 1216932:CM240_RS15040
uniprot id: W6SK40
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1216932:CM240 RS00590
gene id: 1216932:CM240_RS00590
uniprot id: W6RUJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS07815
gene id: 1216932:CM240_RS07815
uniprot id: W6SGA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1216932:CM240 RS12760
gene id: 1216932:CM240_RS12760
uniprot id: W6RZ07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS12865
gene id: 1216932:CM240_RS12865
uniprot id: W6RZ24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS14040
gene id: 1216932:CM240_RS14040
uniprot id: W6S6F6
names: Similarity
messages: Belongs to the DapB family.

1216932:CM240 RS15950
gene id: 1216932:CM240_RS15950
uniprot id: W6S364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS13565
gene id: 1216932:CM240_RS13565
uniprot id: W6S1U3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1216932:CM240 RS16435
gene id: 1216932:CM240_RS16435
uniprot id: W6SKM5
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS01610
gene id: 1216932:CM240_RS01610
uniprot id: W6RTB1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1216932:CM240 RS04080
gene id: 1216932:CM240_RS04080
uniprot id: W6RWI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1216932:CM240 RS09730
gene id: 1216932:CM240_RS09730
uniprot id: W6RWR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1216932:CM240 RS09760
gene id: 1216932:CM240_RS09760
uniprot id: W6S468
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1216932:CM240 RS04500
gene id: 1216932:CM240_RS04500
uniprot id: W6SEJ3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1216932:CM240 RS12180
gene id: 1216932:CM240_RS12180
uniprot id: W6RY61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1216932:CM240 RS15390
gene id: 1216932:CM240_RS15390
uniprot id: W6S2U9
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1216932:CM240 RS06845
gene id: 1216932:CM240_RS06845
uniprot id: W6S2L7
names: Subcellular Location Annotation
messages: Virion

1216932:CM240 RS07475
gene id: 1216932:CM240_RS07475
uniprot id: W6RVF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1216932:CM240 RS03695
gene id: 1216932:CM240_RS03695
uniprot id: W6S0W4
names: Similarity
messages: Belongs to the TrpC family.

1216932:CM240 RS04270
gene id: 1216932:CM240_RS04270
uniprot id: W6RUP5
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1216932:CM240 RS07820
gene id: 1216932:CM240_RS07820
uniprot id: W6RVL9
names: Similarity
messages: Belongs to the GSP E family.

1216932:CM240 RS02615
gene id: 1216932:CM240_RS02615
uniprot id: W6S098
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1216932:CM240 RS12170
gene id: 1216932:CM240_RS12170
uniprot id: W6S153
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1216932:CM240 RS07250
gene id: 1216932:CM240_RS07250
uniprot id: W6RVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1216932:CM240 RS10635
gene id: 1216932:CM240_RS10635
uniprot id: W6S0B8
names: Similarity
messages: Belongs to the DCK/DGK family.

1216932:CM240 RS10325
gene id: 1216932:CM240_RS10325
uniprot id: W6RXQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1216932:CM240 RS12230
gene id: 1216932:CM240_RS12230
uniprot id: W6SIW2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1216932:CM240 RS10920
gene id: 1216932:CM240_RS10920
uniprot id: W6S0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1216932:CM240 RS07695
gene id: 1216932:CM240_RS07695
uniprot id: W6RYL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1216932:CM240 RS05800
gene id: 1216932:CM240_RS05800
uniprot id: W6S200
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1216932:CM240 RS13235
gene id: 1216932:CM240_RS13235
uniprot id: W6SJC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1216932:CM240 RS15425
gene id: 1216932:CM240_RS15425
uniprot id: W6S011
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1216932:CM240 RS04565
gene id: 1216932:CM240_RS04565
uniprot id: W6RU09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1216932:CM240 RS05405
gene id: 1216932:CM240_RS05405
uniprot id: W6RVA4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1216932:CM240 RS07775
gene id: 1216932:CM240_RS07775
uniprot id: W6RVK9
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1216932:CM240 RS11955
gene id: 1216932:CM240_RS11955
uniprot id: W6RY18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1216932:CM240 RS15775
gene id: 1216932:CM240_RS15775
uniprot id: W6S331
names: Subcellular Location Annotation
messages: Membrane

1216932:CM240 RS00520
gene id: 1216932:CM240_RS00520
uniprot id: W6RUH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1216932:CM240 RS05960
gene id: 1216932:CM240_RS05960
uniprot id: W6RXL6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1216932:CM240 RS05755
gene id: 1216932:CM240_RS05755
uniprot id: W6RVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1216932:CM240 RS10460
gene id: 1216932:CM240_RS10460
uniprot id: W6S086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane