1192864:LEP1GSC190 RS10735
gene id: 1192864:LEP1GSC190_RS10735
uniprot id: A0A3Q9DVM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1192864:LEP1GSC190 RS07500
gene id: 1192864:LEP1GSC190_RS07500
uniprot id: A0A3Q9DUN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1192864:LEP1GSC190 RS01265
gene id: 1192864:LEP1GSC190_RS01265
uniprot id: A0A3S9KGL8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1192864:LEP1GSC190 RS02155
gene id: 1192864:LEP1GSC190_RS02155
uniprot id: A0A3S9KH34
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1192864:LEP1GSC190 RS06150
gene id: 1192864:LEP1GSC190_RS06150
uniprot id: A0A3Q9DSI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1192864:LEP1GSC190 RS14440
gene id: 1192864:LEP1GSC190_RS14440
uniprot id: A0A3S9KMW2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS11350
gene id: 1192864:LEP1GSC190_RS11350
uniprot id: A0A3Q9DVT2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1192864:LEP1GSC190 RS14265
gene id: 1192864:LEP1GSC190_RS14265
uniprot id: A0A3S9KMU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1192864:LEP1GSC190 RS09880
gene id: 1192864:LEP1GSC190_RS09880
uniprot id: A0A3S9KPZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1192864:LEP1GSC190 RS06115
gene id: 1192864:LEP1GSC190_RS06115
uniprot id: A0A3Q9DTN5
names: Similarity
messages: Belongs to the UPF0758 family.

1192864:LEP1GSC190 RS18390
gene id: 1192864:LEP1GSC190_RS18390
uniprot id: A0A3Q9DYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS03615
gene id: 1192864:LEP1GSC190_RS03615
uniprot id: A0A3Q9DTI0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1192864:LEP1GSC190 RS07280
gene id: 1192864:LEP1GSC190_RS07280
uniprot id: A0A3S9KJG4
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS09630
gene id: 1192864:LEP1GSC190_RS09630
uniprot id: A0A3Q9DTV2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1192864:LEP1GSC190 RS14085
gene id: 1192864:LEP1GSC190_RS14085
uniprot id: A0A3Q9DVV2
names: Similarity
messages: Belongs to the GST superfamily.

1192864:LEP1GSC190 RS11445
gene id: 1192864:LEP1GSC190_RS11445
uniprot id: A0A3S9KLI1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1192864:LEP1GSC190 RS00215
gene id: 1192864:LEP1GSC190_RS00215
uniprot id: A0A3S9KG69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS16025
gene id: 1192864:LEP1GSC190_RS16025
uniprot id: A0A3S9KQ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1192864:LEP1GSC190 RS03935
gene id: 1192864:LEP1GSC190_RS03935
uniprot id: A0A3S9KHW8
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS15045
gene id: 1192864:LEP1GSC190_RS15045
uniprot id: A0A3S9KN68
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1192864:LEP1GSC190 RS09415
gene id: 1192864:LEP1GSC190_RS09415
uniprot id: A0A3Q9DV91
names: Similarity
messages: Belongs to the FGGY kinase family.

1192864:LEP1GSC190 RS09030
gene id: 1192864:LEP1GSC190_RS09030
uniprot id: A0A3Q9DUG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1192864:LEP1GSC190 RS11495
gene id: 1192864:LEP1GSC190_RS11495
uniprot id: A0A3S9KLF2
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS15170
gene id: 1192864:LEP1GSC190_RS15170
uniprot id: A0A3Q9DUP7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1192864:LEP1GSC190 RS12955
gene id: 1192864:LEP1GSC190_RS12955
uniprot id: A0A3Q9DW16
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1192864:LEP1GSC190 RS07535
gene id: 1192864:LEP1GSC190_RS07535
uniprot id: A0A3Q9DUJ1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1192864:LEP1GSC190 RS08570
gene id: 1192864:LEP1GSC190_RS08570
uniprot id: A0A3S9KK72
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1192864:LEP1GSC190 RS18080
gene id: 1192864:LEP1GSC190_RS18080
uniprot id: A0A3Q9DY74
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1192864:LEP1GSC190 RS09445
gene id: 1192864:LEP1GSC190_RS09445
uniprot id: A0A3Q9DUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS05710
gene id: 1192864:LEP1GSC190_RS05710
uniprot id: A0A3Q9DUF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1192864:LEP1GSC190 RS01985
gene id: 1192864:LEP1GSC190_RS01985
uniprot id: A0A3S9KGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1192864:LEP1GSC190 RS15280
gene id: 1192864:LEP1GSC190_RS15280
uniprot id: A0A3S9KNC5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1192864:LEP1GSC190 RS16155
gene id: 1192864:LEP1GSC190_RS16155
uniprot id: A0A3Q9DWW7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS01595
gene id: 1192864:LEP1GSC190_RS01595
uniprot id: A0A3S9KGS9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1192864:LEP1GSC190 RS12625
gene id: 1192864:LEP1GSC190_RS12625
uniprot id: A0A3Q9DVY8
names: Similarity
messages: Belongs to the AHA1 family.

1192864:LEP1GSC190 RS08400
gene id: 1192864:LEP1GSC190_RS08400
uniprot id: A0A3S9KPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1192864:LEP1GSC190 RS04305
gene id: 1192864:LEP1GSC190_RS04305
uniprot id: A0A3Q9DS43
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1192864:LEP1GSC190 RS11545
gene id: 1192864:LEP1GSC190_RS11545
uniprot id: A0A3Q9DVK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1192864:LEP1GSC190 RS15845
gene id: 1192864:LEP1GSC190_RS15845
uniprot id: A0A3S9KNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1192864:LEP1GSC190 RS00255
gene id: 1192864:LEP1GSC190_RS00255
uniprot id: A0A3Q9DSW1
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS13455
gene id: 1192864:LEP1GSC190_RS13455
uniprot id: A0A3S9KMG4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1192864:LEP1GSC190 RS06005
gene id: 1192864:LEP1GSC190_RS06005
uniprot id: A0A3S9KIT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1192864:LEP1GSC190 RS18100
gene id: 1192864:LEP1GSC190_RS18100
uniprot id: A0A3S9KQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS16055
gene id: 1192864:LEP1GSC190_RS16055
uniprot id: A0A3Q9DWY7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1192864:LEP1GSC190 RS09480
gene id: 1192864:LEP1GSC190_RS09480
uniprot id: A0A3S9KKI5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1192864:LEP1GSC190 RS11330
gene id: 1192864:LEP1GSC190_RS11330
uniprot id: A0A3Q9DVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1192864:LEP1GSC190 RS04140
gene id: 1192864:LEP1GSC190_RS04140
uniprot id: A0A3S9KI01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1192864:LEP1GSC190 RS09950
gene id: 1192864:LEP1GSC190_RS09950
uniprot id: A0A3S9KKS4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS06220
gene id: 1192864:LEP1GSC190_RS06220
uniprot id: A0A3S9KIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1192864:LEP1GSC190 RS07715
gene id: 1192864:LEP1GSC190_RS07715
uniprot id: A0A3S9KJM6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1192864:LEP1GSC190 RS01080
gene id: 1192864:LEP1GSC190_RS01080
uniprot id: A0A3Q9DST5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS17090
gene id: 1192864:LEP1GSC190_RS17090
uniprot id: A0A3Q9DXB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1192864:LEP1GSC190 RS11205
gene id: 1192864:LEP1GSC190_RS11205
uniprot id: A0A3Q9DVH3
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS12360
gene id: 1192864:LEP1GSC190_RS12360
uniprot id: A0A3S9KLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1192864:LEP1GSC190 RS07210
gene id: 1192864:LEP1GSC190_RS07210
uniprot id: A0A3S9KJF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1192864:LEP1GSC190 RS18985
gene id: 1192864:LEP1GSC190_RS18985
uniprot id: A0A3S9KR08
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS08795
gene id: 1192864:LEP1GSC190_RS08795
uniprot id: A0A3S9KKA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS11370
gene id: 1192864:LEP1GSC190_RS11370
uniprot id: A0A3Q9DVM9
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1192864:LEP1GSC190 RS08355
gene id: 1192864:LEP1GSC190_RS08355
uniprot id: A0A3S9KJY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1192864:LEP1GSC190 RS01720
gene id: 1192864:LEP1GSC190_RS01720
uniprot id: A0A3Q9DSM9
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS08100
gene id: 1192864:LEP1GSC190_RS08100
uniprot id: A0A3Q9DXV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

1192864:LEP1GSC190 RS02870
gene id: 1192864:LEP1GSC190_RS02870
uniprot id: A0A3S9KHH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1192864:LEP1GSC190 RS12435
gene id: 1192864:LEP1GSC190_RS12435
uniprot id: A0A3S9KM01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1192864:LEP1GSC190 RS08215
gene id: 1192864:LEP1GSC190_RS08215
uniprot id: A0A3S9KJW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1192864:LEP1GSC190 RS01590
gene id: 1192864:LEP1GSC190_RS01590
uniprot id: A0A3Q9DR80
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1192864:LEP1GSC190 RS10275
gene id: 1192864:LEP1GSC190_RS10275
uniprot id: A0A3Q9DVP1
names: Similarity
messages: Belongs to the thioredoxin family.

1192864:LEP1GSC190 RS00685
gene id: 1192864:LEP1GSC190_RS00685
uniprot id: A0A3Q9DRI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1192864:LEP1GSC190 RS13340
gene id: 1192864:LEP1GSC190_RS13340
uniprot id: A0A3Q9DW56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1192864:LEP1GSC190 RS17175
gene id: 1192864:LEP1GSC190_RS17175
uniprot id: A0A3Q9DX67
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS01205
gene id: 1192864:LEP1GSC190_RS01205
uniprot id: A0A3Q9DRP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1192864:LEP1GSC190 RS10110
gene id: 1192864:LEP1GSC190_RS10110
uniprot id: A0A3S9KKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1192864:LEP1GSC190 RS15065
gene id: 1192864:LEP1GSC190_RS15065
uniprot id: A0A3S9KN85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1192864:LEP1GSC190 RS04805
gene id: 1192864:LEP1GSC190_RS04805
uniprot id: A0A3Q9DTA9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1192864:LEP1GSC190 RS09325
gene id: 1192864:LEP1GSC190_RS09325
uniprot id: A0A3S9KKG0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1192864:LEP1GSC190 RS05345
gene id: 1192864:LEP1GSC190_RS05345
uniprot id: A0A3S9KIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS06940
gene id: 1192864:LEP1GSC190_RS06940
uniprot id: A0A3Q9DTV5
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1192864:LEP1GSC190 RS10755
gene id: 1192864:LEP1GSC190_RS10755
uniprot id: A0A3Q9DVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1192864:LEP1GSC190 RS05385
gene id: 1192864:LEP1GSC190_RS05385
uniprot id: A0A3S9KII8
names: Similarity
messages: Belongs to the histone deacetylase family.

1192864:LEP1GSC190 RS16645
gene id: 1192864:LEP1GSC190_RS16645
uniprot id: A0A3Q9DXD8
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS11000
gene id: 1192864:LEP1GSC190_RS11000
uniprot id: A0A3Q9DVV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1192864:LEP1GSC190 RS14435
gene id: 1192864:LEP1GSC190_RS14435
uniprot id: A0A3Q9DV40
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1192864:LEP1GSC190 RS00175
gene id: 1192864:LEP1GSC190_RS00175
uniprot id: A0A3S9KG65
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1192864:LEP1GSC190 RS18825
gene id: 1192864:LEP1GSC190_RS18825
uniprot id: A0A3S9KQZ7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1192864:LEP1GSC190 RS09655
gene id: 1192864:LEP1GSC190_RS09655
uniprot id: A0A3S9KKL7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1192864:LEP1GSC190 RS07070
gene id: 1192864:LEP1GSC190_RS07070
uniprot id: A0A3S9KJB0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1192864:LEP1GSC190 RS15340
gene id: 1192864:LEP1GSC190_RS15340
uniprot id: A0A3Q9DUR2
names: Subcellular Location Annotation
messages: Periplasmic flagellum

1192864:LEP1GSC190 RS16885
gene id: 1192864:LEP1GSC190_RS16885
uniprot id: A0A3Q9DX79
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS08510
gene id: 1192864:LEP1GSC190_RS08510
uniprot id: A0A3Q9DUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1192864:LEP1GSC190 RS02650
gene id: 1192864:LEP1GSC190_RS02650
uniprot id: A0A3Q9DTK9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1192864:LEP1GSC190 RS08390
gene id: 1192864:LEP1GSC190_RS08390
uniprot id: A0A3S9KJZ3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1192864:LEP1GSC190 RS13330
gene id: 1192864:LEP1GSC190_RS13330
uniprot id: A0A3Q9DW94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1192864:LEP1GSC190 RS05680
gene id: 1192864:LEP1GSC190_RS05680
uniprot id: A0A3Q9DU15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1192864:LEP1GSC190 RS02895
gene id: 1192864:LEP1GSC190_RS02895
uniprot id: A0A3S9KHF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1192864:LEP1GSC190 RS02470
gene id: 1192864:LEP1GSC190_RS02470
uniprot id: A0A3Q9DTI1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1192864:LEP1GSC190 RS13785
gene id: 1192864:LEP1GSC190_RS13785
uniprot id: A0A3S9KMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1192864:LEP1GSC190 RS00475
gene id: 1192864:LEP1GSC190_RS00475
uniprot id: A0A3Q9DSG3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1192864:LEP1GSC190 RS06010
gene id: 1192864:LEP1GSC190_RS06010
uniprot id: A0A3Q9DUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1192864:LEP1GSC190 RS12175
gene id: 1192864:LEP1GSC190_RS12175
uniprot id: A0A3Q9DUJ9
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS02945
gene id: 1192864:LEP1GSC190_RS02945
uniprot id: A0A3S9KHG2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1192864:LEP1GSC190 RS03950
gene id: 1192864:LEP1GSC190_RS03950
uniprot id: A0A3S9KHW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1192864:LEP1GSC190 RS02335
gene id: 1192864:LEP1GSC190_RS02335
uniprot id: A0A3Q9DSR3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1192864:LEP1GSC190 RS16390
gene id: 1192864:LEP1GSC190_RS16390
uniprot id: A0A3Q9DW99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1192864:LEP1GSC190 RS01495
gene id: 1192864:LEP1GSC190_RS01495
uniprot id: A0A3Q9DSV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1192864:LEP1GSC190 RS08315
gene id: 1192864:LEP1GSC190_RS08315
uniprot id: A0A3Q9DUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1192864:LEP1GSC190 RS00030
gene id: 1192864:LEP1GSC190_RS00030
uniprot id: A0A3Q9DSR0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1192864:LEP1GSC190 RS13625
gene id: 1192864:LEP1GSC190_RS13625
uniprot id: A0A3Q9DUW6
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS10095
gene id: 1192864:LEP1GSC190_RS10095
uniprot id: A0A3Q9DVJ1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1192864:LEP1GSC190 RS12325
gene id: 1192864:LEP1GSC190_RS12325
uniprot id: A0A3S9KLX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1192864:LEP1GSC190 RS03915
gene id: 1192864:LEP1GSC190_RS03915
uniprot id: A0A3Q9DTV6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1192864:LEP1GSC190 RS06090
gene id: 1192864:LEP1GSC190_RS06090
uniprot id: A0A3Q9DUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1192864:LEP1GSC190 RS18225
gene id: 1192864:LEP1GSC190_RS18225
uniprot id: A0A3Q9DY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1192864:LEP1GSC190 RS16660
gene id: 1192864:LEP1GSC190_RS16660
uniprot id: A0A3Q9DWC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS09860
gene id: 1192864:LEP1GSC190_RS09860
uniprot id: A0A3Q9DUM9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1192864:LEP1GSC190 RS02880
gene id: 1192864:LEP1GSC190_RS02880
uniprot id: A0A3Q9DTL2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1192864:LEP1GSC190 RS08985
gene id: 1192864:LEP1GSC190_RS08985
uniprot id: A0A3Q9DUU9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1192864:LEP1GSC190 RS03580
gene id: 1192864:LEP1GSC190_RS03580
uniprot id: A0A3Q9DWQ3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1192864:LEP1GSC190 RS06145
gene id: 1192864:LEP1GSC190_RS06145
uniprot id: A0A3S9KIY6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1192864:LEP1GSC190 RS10900
gene id: 1192864:LEP1GSC190_RS10900
uniprot id: A0A3S9KPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1192864:LEP1GSC190 RS09265
gene id: 1192864:LEP1GSC190_RS09265
uniprot id: A0A3S9KKE5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1192864:LEP1GSC190 RS14770
gene id: 1192864:LEP1GSC190_RS14770
uniprot id: A0A3Q9DV81
names: Similarity
messages: Belongs to the DEAD box helicase family.

1192864:LEP1GSC190 RS13225
gene id: 1192864:LEP1GSC190_RS13225
uniprot id: A0A3Q9DVH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1192864:LEP1GSC190 RS15165
gene id: 1192864:LEP1GSC190_RS15165
uniprot id: A0A3S9KNA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1192864:LEP1GSC190 RS10765
gene id: 1192864:LEP1GSC190_RS10765
uniprot id: A0A3Q9DU68
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS10505
gene id: 1192864:LEP1GSC190_RS10505
uniprot id: A0A3S9KL38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1192864:LEP1GSC190 RS12995
gene id: 1192864:LEP1GSC190_RS12995
uniprot id: A0A3S9KM90
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS16700
gene id: 1192864:LEP1GSC190_RS16700
uniprot id: A0A3Q9DWK7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS11340
gene id: 1192864:LEP1GSC190_RS11340
uniprot id: A0A3S9KLF7
names: Similarity
messages: Belongs to the peptidase S41A family.

1192864:LEP1GSC190 RS16855
gene id: 1192864:LEP1GSC190_RS16855
uniprot id: A0A3Q9DXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1192864:LEP1GSC190 RS15815
gene id: 1192864:LEP1GSC190_RS15815
uniprot id: A0A3Q9DWS8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1192864:LEP1GSC190 RS15325
gene id: 1192864:LEP1GSC190_RS15325
uniprot id: A0A3Q9DWP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1192864:LEP1GSC190 RS08395
gene id: 1192864:LEP1GSC190_RS08395
uniprot id: A0A3Q9DUP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1192864:LEP1GSC190 RS03355
gene id: 1192864:LEP1GSC190_RS03355
uniprot id: A0A3Q9DSY4
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1192864:LEP1GSC190 RS13910
gene id: 1192864:LEP1GSC190_RS13910
uniprot id: A0A3Q9DVM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS11540
gene id: 1192864:LEP1GSC190_RS11540
uniprot id: A0A3Q9DUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1192864:LEP1GSC190 RS14280
gene id: 1192864:LEP1GSC190_RS14280
uniprot id: A0A3Q9DWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1192864:LEP1GSC190 RS04560
gene id: 1192864:LEP1GSC190_RS04560
uniprot id: A0A3Q9DTZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1192864:LEP1GSC190 RS05450
gene id: 1192864:LEP1GSC190_RS05450
uniprot id: A0A3Q9DU92
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1192864:LEP1GSC190 RS03095
gene id: 1192864:LEP1GSC190_RS03095
uniprot id: A0A3Q9DWP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1192864:LEP1GSC190 RS16215
gene id: 1192864:LEP1GSC190_RS16215
uniprot id: A0A3S9KNP0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1192864:LEP1GSC190 RS16820
gene id: 1192864:LEP1GSC190_RS16820
uniprot id: A0A3Q9DX34
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS07890
gene id: 1192864:LEP1GSC190_RS07890
uniprot id: A0A3S9KJQ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1192864:LEP1GSC190 RS12250
gene id: 1192864:LEP1GSC190_RS12250
uniprot id: A0A3Q9DVZ7
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1192864:LEP1GSC190 RS03020
gene id: 1192864:LEP1GSC190_RS03020
uniprot id: A0A3S9KHG4
names: Similarity
messages: Belongs to the GARS family.

1192864:LEP1GSC190 RS10000
gene id: 1192864:LEP1GSC190_RS10000
uniprot id: A0A3Q9DVH7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS06770
gene id: 1192864:LEP1GSC190_RS06770
uniprot id: A0A3S9KJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1192864:LEP1GSC190 RS01890
gene id: 1192864:LEP1GSC190_RS01890
uniprot id: A0A3Q9DSN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1192864:LEP1GSC190 RS00010
gene id: 1192864:LEP1GSC190_RS00010
uniprot id: A0A3Q9DSY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1192864:LEP1GSC190 RS08360
gene id: 1192864:LEP1GSC190_RS08360
uniprot id: A0A3Q9DUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1192864:LEP1GSC190 RS02350
gene id: 1192864:LEP1GSC190_RS02350
uniprot id: A0A3S9KH90
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1192864:LEP1GSC190 RS03300
gene id: 1192864:LEP1GSC190_RS03300
uniprot id: A0A3Q9DTC0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1192864:LEP1GSC190 RS00655
gene id: 1192864:LEP1GSC190_RS00655
uniprot id: A0A3S9KGF6
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS14560
gene id: 1192864:LEP1GSC190_RS14560
uniprot id: A0A3S9KMY0
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1192864:LEP1GSC190 RS18935
gene id: 1192864:LEP1GSC190_RS18935
uniprot id: A0A3Q9DYG8
names: Similarity
messages: Belongs to the ParB family.

1192864:LEP1GSC190 RS02300
gene id: 1192864:LEP1GSC190_RS02300
uniprot id: A0A3S9KH80
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS09615
gene id: 1192864:LEP1GSC190_RS09615
uniprot id: A0A3Q9DV64
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1192864:LEP1GSC190 RS00470
gene id: 1192864:LEP1GSC190_RS00470
uniprot id: A0A3S9KPE0
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS03960
gene id: 1192864:LEP1GSC190_RS03960
uniprot id: A0A3S9KHZ5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1192864:LEP1GSC190 RS10665
gene id: 1192864:LEP1GSC190_RS10665
uniprot id: A0A3Q9DVG8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS00170
gene id: 1192864:LEP1GSC190_RS00170
uniprot id: A0A3Q9DRC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS17140
gene id: 1192864:LEP1GSC190_RS17140
uniprot id: A0A3Q9DXA1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1192864:LEP1GSC190 RS09235
gene id: 1192864:LEP1GSC190_RS09235
uniprot id: A0A3Q9DV23
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1192864:LEP1GSC190 RS17280
gene id: 1192864:LEP1GSC190_RS17280
uniprot id: A0A3Q9DXB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1192864:LEP1GSC190 RS13070
gene id: 1192864:LEP1GSC190_RS13070
uniprot id: A0A3Q9DVY1
names: Similarity
messages: Belongs to the peptidase S1C family.

1192864:LEP1GSC190 RS06410
gene id: 1192864:LEP1GSC190_RS06410
uniprot id: A0A3Q9DTQ5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1192864:LEP1GSC190 RS03025
gene id: 1192864:LEP1GSC190_RS03025
uniprot id: A0A3S9KHG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1192864:LEP1GSC190 RS17535
gene id: 1192864:LEP1GSC190_RS17535
uniprot id: A0A3S9KQA0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1192864:LEP1GSC190 RS04755
gene id: 1192864:LEP1GSC190_RS04755
uniprot id: A0A3S9KI99
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1192864:LEP1GSC190 RS09425
gene id: 1192864:LEP1GSC190_RS09425
uniprot id: A0A3Q9DUK3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1192864:LEP1GSC190 RS06595
gene id: 1192864:LEP1GSC190_RS06595
uniprot id: A0A3Q9DTS3
names: Similarity
messages: Belongs to the MreC family.

1192864:LEP1GSC190 RS04375
gene id: 1192864:LEP1GSC190_RS04375
uniprot id: A0A3S9KI33
names: Similarity
messages: Belongs to the peptidase M1 family.

1192864:LEP1GSC190 RS08030
gene id: 1192864:LEP1GSC190_RS08030
uniprot id: A0A3S9KJV4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1192864:LEP1GSC190 RS18165
gene id: 1192864:LEP1GSC190_RS18165
uniprot id: A0A3Q9DXW5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1192864:LEP1GSC190 RS04525
gene id: 1192864:LEP1GSC190_RS04525
uniprot id: A0A3Q9DSJ0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1192864:LEP1GSC190 RS17685
gene id: 1192864:LEP1GSC190_RS17685
uniprot id: A0A3S9KQE2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1192864:LEP1GSC190 RS12200
gene id: 1192864:LEP1GSC190_RS12200
uniprot id: A0A3Q9DVR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS10430
gene id: 1192864:LEP1GSC190_RS10430
uniprot id: A0A3Q9DU39
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS08285
gene id: 1192864:LEP1GSC190_RS08285
uniprot id: A0A3S9KJY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

1192864:LEP1GSC190 RS06510
gene id: 1192864:LEP1GSC190_RS06510
uniprot id: A0A3Q9DU65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1192864:LEP1GSC190 RS15180
gene id: 1192864:LEP1GSC190_RS15180
uniprot id: A0A3Q9DWI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1192864:LEP1GSC190 RS06330
gene id: 1192864:LEP1GSC190_RS06330
uniprot id: A0A3Q9DUH2
names: Similarity
messages: Belongs to the NTE family.

1192864:LEP1GSC190 RS15810
gene id: 1192864:LEP1GSC190_RS15810
uniprot id: A0A3Q9DX27
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1192864:LEP1GSC190 RS14275
gene id: 1192864:LEP1GSC190_RS14275
uniprot id: A0A3Q9DWI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS17085
gene id: 1192864:LEP1GSC190_RS17085
uniprot id: A0A3S9KP47
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS07505
gene id: 1192864:LEP1GSC190_RS07505
uniprot id: A0A3S9KJM9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1192864:LEP1GSC190 RS17250
gene id: 1192864:LEP1GSC190_RS17250
uniprot id: A0A3S9KP81
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1192864:LEP1GSC190 RS07240
gene id: 1192864:LEP1GSC190_RS07240
uniprot id: A0A3Q9DSQ5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1192864:LEP1GSC190 RS03985
gene id: 1192864:LEP1GSC190_RS03985
uniprot id: A0A3Q9DSG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1192864:LEP1GSC190 RS06545
gene id: 1192864:LEP1GSC190_RS06545
uniprot id: A0A3Q9DUF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1192864:LEP1GSC190 RS01935
gene id: 1192864:LEP1GSC190_RS01935
uniprot id: A0A3Q9DTF4
names: Similarity
messages: Belongs to the DprA/Smf family.

1192864:LEP1GSC190 RS00405
gene id: 1192864:LEP1GSC190_RS00405
uniprot id: A0A3Q9DSF2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1192864:LEP1GSC190 RS11335
gene id: 1192864:LEP1GSC190_RS11335
uniprot id: A0A3Q9DV10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1192864:LEP1GSC190 RS08980
gene id: 1192864:LEP1GSC190_RS08980
uniprot id: A0A3Q9DTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1192864:LEP1GSC190 RS15185
gene id: 1192864:LEP1GSC190_RS15185
uniprot id: A0A3Q9DWY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1192864:LEP1GSC190 RS14285
gene id: 1192864:LEP1GSC190_RS14285
uniprot id: A0A3Q9DVX3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1192864:LEP1GSC190 RS16810
gene id: 1192864:LEP1GSC190_RS16810
uniprot id: A0A3S9KP01
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1192864:LEP1GSC190 RS14255
gene id: 1192864:LEP1GSC190_RS14255
uniprot id: A0A3S9KMS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1192864:LEP1GSC190 RS09490
gene id: 1192864:LEP1GSC190_RS09490
uniprot id: A0A3S9KKJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1192864:LEP1GSC190 RS07540
gene id: 1192864:LEP1GSC190_RS07540
uniprot id: A0A3S9KJL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1192864:LEP1GSC190 RS00250
gene id: 1192864:LEP1GSC190_RS00250
uniprot id: A0A3S9KG62
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1192864:LEP1GSC190 RS02040
gene id: 1192864:LEP1GSC190_RS02040
uniprot id: A0A3S9KGZ7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1192864:LEP1GSC190 RS11985
gene id: 1192864:LEP1GSC190_RS11985
uniprot id: A0A3Q9DV98
names: Similarity
messages: Belongs to the YciI family.

1192864:LEP1GSC190 RS10770
gene id: 1192864:LEP1GSC190_RS10770
uniprot id: A0A3Q9DVD5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1192864:LEP1GSC190 RS02890
gene id: 1192864:LEP1GSC190_RS02890
uniprot id: A0A3S9KHF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1192864:LEP1GSC190 RS04135
gene id: 1192864:LEP1GSC190_RS04135
uniprot id: A0A3S9KHZ1
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS05525
gene id: 1192864:LEP1GSC190_RS05525
uniprot id: A0A3Q9DTH4
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS02375
gene id: 1192864:LEP1GSC190_RS02375
uniprot id: A0A3S9KH61
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1192864:LEP1GSC190 RS15100
gene id: 1192864:LEP1GSC190_RS15100
uniprot id: A0A3Q9DVB3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1192864:LEP1GSC190 RS03235
gene id: 1192864:LEP1GSC190_RS03235
uniprot id: A0A3Q9DTN7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1192864:LEP1GSC190 RS12680
gene id: 1192864:LEP1GSC190_RS12680
uniprot id: A0A3Q9DVC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1192864:LEP1GSC190 RS12545
gene id: 1192864:LEP1GSC190_RS12545
uniprot id: A0A3S9KM13
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS00505
gene id: 1192864:LEP1GSC190_RS00505
uniprot id: A0A3Q9DST9
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS01115
gene id: 1192864:LEP1GSC190_RS01115
uniprot id: A0A3S9KGI2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS00025
gene id: 1192864:LEP1GSC190_RS00025
uniprot id: A0A3Q9DSD3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1192864:LEP1GSC190 RS01655
gene id: 1192864:LEP1GSC190_RS01655
uniprot id: A0A3S9KGU3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1192864:LEP1GSC190 RS17420
gene id: 1192864:LEP1GSC190_RS17420
uniprot id: A0A3S9KPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1192864:LEP1GSC190 RS05760
gene id: 1192864:LEP1GSC190_RS05760
uniprot id: A0A3Q9DXA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1192864:LEP1GSC190 RS09220
gene id: 1192864:LEP1GSC190_RS09220
uniprot id: A0A3Q9DUI4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1192864:LEP1GSC190 RS08255
gene id: 1192864:LEP1GSC190_RS08255
uniprot id: A0A3S9KJX5
names: Similarity
messages: Belongs to the UPF0102 family.

1192864:LEP1GSC190 RS13960
gene id: 1192864:LEP1GSC190_RS13960
uniprot id: A0A3S9KMM5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1192864:LEP1GSC190 RS13265
gene id: 1192864:LEP1GSC190_RS13265
uniprot id: A0A3Q9DUT9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS09975
gene id: 1192864:LEP1GSC190_RS09975
uniprot id: A0A3Q9DV49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1192864:LEP1GSC190 RS11665
gene id: 1192864:LEP1GSC190_RS11665
uniprot id: A0A3S9KLL7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS04430
gene id: 1192864:LEP1GSC190_RS04430
uniprot id: A0A3Q9DU19
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1192864:LEP1GSC190 RS15130
gene id: 1192864:LEP1GSC190_RS15130
uniprot id: A0A3Q9DVZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1192864:LEP1GSC190 RS17115
gene id: 1192864:LEP1GSC190_RS17115
uniprot id: A0A3S9KP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1192864:LEP1GSC190 RS15120
gene id: 1192864:LEP1GSC190_RS15120
uniprot id: A0A3S9KN72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1192864:LEP1GSC190 RS18110
gene id: 1192864:LEP1GSC190_RS18110
uniprot id: A0A3Q9DXJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1192864:LEP1GSC190 RS06565
gene id: 1192864:LEP1GSC190_RS06565
uniprot id: A0A3Q9DUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS12905
gene id: 1192864:LEP1GSC190_RS12905
uniprot id: A0A3Q9DVE2
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS07090
gene id: 1192864:LEP1GSC190_RS07090
uniprot id: A0A3Q9DTX7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1192864:LEP1GSC190 RS18475
gene id: 1192864:LEP1GSC190_RS18475
uniprot id: A0A3Q9DYJ1
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS09485
gene id: 1192864:LEP1GSC190_RS09485
uniprot id: A0A3Q9DVA1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1192864:LEP1GSC190 RS09560
gene id: 1192864:LEP1GSC190_RS09560
uniprot id: A0A3S9KKJ3
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS11805
gene id: 1192864:LEP1GSC190_RS11805
uniprot id: A0A3S9KLM0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1192864:LEP1GSC190 RS10090
gene id: 1192864:LEP1GSC190_RS10090
uniprot id: A0A3Q9DUR0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1192864:LEP1GSC190 RS08450
gene id: 1192864:LEP1GSC190_RS08450
uniprot id: A0A3S9KK04
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS08470
gene id: 1192864:LEP1GSC190_RS08470
uniprot id: A0A3Q9DSZ5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1192864:LEP1GSC190 RS00130
gene id: 1192864:LEP1GSC190_RS00130
uniprot id: A0A3S9KG41
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1192864:LEP1GSC190 RS09085
gene id: 1192864:LEP1GSC190_RS09085
uniprot id: A0A3Q9DUE3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1192864:LEP1GSC190 RS12270
gene id: 1192864:LEP1GSC190_RS12270
uniprot id: A0A3S9KLV0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1192864:LEP1GSC190 RS13375
gene id: 1192864:LEP1GSC190_RS13375
uniprot id: A0A3S9KMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

1192864:LEP1GSC190 RS08515
gene id: 1192864:LEP1GSC190_RS08515
uniprot id: A0A3S9KK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1192864:LEP1GSC190 RS12645
gene id: 1192864:LEP1GSC190_RS12645
uniprot id: A0A3S9KM28
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1192864:LEP1GSC190 RS02245
gene id: 1192864:LEP1GSC190_RS02245
uniprot id: A0A3S9KPF7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS13450
gene id: 1192864:LEP1GSC190_RS13450
uniprot id: A0A3S9KMG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1192864:LEP1GSC190 RS05935
gene id: 1192864:LEP1GSC190_RS05935
uniprot id: A0A3S9KIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1192864:LEP1GSC190 RS01440
gene id: 1192864:LEP1GSC190_RS01440
uniprot id: A0A3Q9DT44
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1192864:LEP1GSC190 RS14110
gene id: 1192864:LEP1GSC190_RS14110
uniprot id: A0A3Q9DY14
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS12935
gene id: 1192864:LEP1GSC190_RS12935
uniprot id: A0A3Q9DVH4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1192864:LEP1GSC190 RS12665
gene id: 1192864:LEP1GSC190_RS12665
uniprot id: A0A3S9KM34
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1192864:LEP1GSC190 RS15060
gene id: 1192864:LEP1GSC190_RS15060
uniprot id: A0A3Q9DWR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1192864:LEP1GSC190 RS08290
gene id: 1192864:LEP1GSC190_RS08290
uniprot id: A0A3Q9DUN2
names: Similarity
messages: Belongs to the GSP E family.

1192864:LEP1GSC190 RS16525
gene id: 1192864:LEP1GSC190_RS16525
uniprot id: A0A3S9KNW0
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

1192864:LEP1GSC190 RS17595
gene id: 1192864:LEP1GSC190_RS17595
uniprot id: A0A3S9KQB9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1192864:LEP1GSC190 RS10135
gene id: 1192864:LEP1GSC190_RS10135
uniprot id: A0A3Q9DTH9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1192864:LEP1GSC190 RS09545
gene id: 1192864:LEP1GSC190_RS09545
uniprot id: A0A3S9KKK1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1192864:LEP1GSC190 RS17210
gene id: 1192864:LEP1GSC190_RS17210
uniprot id: A0A3S9KP78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1192864:LEP1GSC190 RS14655
gene id: 1192864:LEP1GSC190_RS14655
uniprot id: A0A3Q9DW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1192864:LEP1GSC190 RS09305
gene id: 1192864:LEP1GSC190_RS09305
uniprot id: A0A3Q9DUJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1192864:LEP1GSC190 RS09460
gene id: 1192864:LEP1GSC190_RS09460
uniprot id: A0A3Q9DUI7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1192864:LEP1GSC190 RS03995
gene id: 1192864:LEP1GSC190_RS03995
uniprot id: A0A3S9KHY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1192864:LEP1GSC190 RS07820
gene id: 1192864:LEP1GSC190_RS07820
uniprot id: A0A3Q9DXQ0
names: Subcellular Location Annotation
messages: Periplasm

1192864:LEP1GSC190 RS03645
gene id: 1192864:LEP1GSC190_RS03645
uniprot id: A0A3Q9DTV7
names: Similarity
messages: Belongs to the peptidase M16 family.

1192864:LEP1GSC190 RS07245
gene id: 1192864:LEP1GSC190_RS07245
uniprot id: A0A3S9KJD7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1192864:LEP1GSC190 RS10450
gene id: 1192864:LEP1GSC190_RS10450
uniprot id: A0A3Q9DUU5
names: Similarity
messages: Belongs to the RemA family.

1192864:LEP1GSC190 RS06915
gene id: 1192864:LEP1GSC190_RS06915
uniprot id: A0A3S9KJ82
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1192864:LEP1GSC190 RS11215
gene id: 1192864:LEP1GSC190_RS11215
uniprot id: A0A3Q9DV01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1192864:LEP1GSC190 RS16030
gene id: 1192864:LEP1GSC190_RS16030
uniprot id: A0A3S9KNK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1192864:LEP1GSC190 RS18400
gene id: 1192864:LEP1GSC190_RS18400
uniprot id: A0A3Q9DYG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS06990
gene id: 1192864:LEP1GSC190_RS06990
uniprot id: A0A3S9KJC3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1192864:LEP1GSC190 RS05685
gene id: 1192864:LEP1GSC190_RS05685
uniprot id: A0A3Q9DSF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1192864:LEP1GSC190 RS08165
gene id: 1192864:LEP1GSC190_RS08165
uniprot id: A0A3S9KJV1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1192864:LEP1GSC190 RS05960
gene id: 1192864:LEP1GSC190_RS05960
uniprot id: A0A3S9KIS5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1192864:LEP1GSC190 RS15835
gene id: 1192864:LEP1GSC190_RS15835
uniprot id: A0A3S9KNI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1192864:LEP1GSC190 RS10960
gene id: 1192864:LEP1GSC190_RS10960
uniprot id: A0A3S9KQ03
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1192864:LEP1GSC190 RS13550
gene id: 1192864:LEP1GSC190_RS13550
uniprot id: A0A3Q9DWC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1192864:LEP1GSC190 RS04260
gene id: 1192864:LEP1GSC190_RS04260
uniprot id: A0A3S9KI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1192864:LEP1GSC190 RS06540
gene id: 1192864:LEP1GSC190_RS06540
uniprot id: A0A3Q9DUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1192864:LEP1GSC190 RS14610
gene id: 1192864:LEP1GSC190_RS14610
uniprot id: A0A3Q9DV59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS17240
gene id: 1192864:LEP1GSC190_RS17240
uniprot id: A0A3S9KP75
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1192864:LEP1GSC190 RS06085
gene id: 1192864:LEP1GSC190_RS06085
uniprot id: A0A3S9KIX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1192864:LEP1GSC190 RS17445
gene id: 1192864:LEP1GSC190_RS17445
uniprot id: A0A3S9KPC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1192864:LEP1GSC190 RS05840
gene id: 1192864:LEP1GSC190_RS05840
uniprot id: A0A3Q9DSS8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1192864:LEP1GSC190 RS12430
gene id: 1192864:LEP1GSC190_RS12430
uniprot id: A0A3S9KLX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1192864:LEP1GSC190 RS10470
gene id: 1192864:LEP1GSC190_RS10470
uniprot id: A0A3S9KKZ4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1192864:LEP1GSC190 RS09375
gene id: 1192864:LEP1GSC190_RS09375
uniprot id: A0A3Q9DVE4
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1192864:LEP1GSC190 RS11440
gene id: 1192864:LEP1GSC190_RS11440
uniprot id: A0A3Q9DVJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1192864:LEP1GSC190 RS06525
gene id: 1192864:LEP1GSC190_RS06525
uniprot id: A0A3S9KJ23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1192864:LEP1GSC190 RS13630
gene id: 1192864:LEP1GSC190_RS13630
uniprot id: A0A3S9KMJ6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1192864:LEP1GSC190 RS19160
gene id: 1192864:LEP1GSC190_RS19160
uniprot id: A0A3Q9DYA8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1192864:LEP1GSC190 RS18005
gene id: 1192864:LEP1GSC190_RS18005
uniprot id: A0A3S9KR24
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1192864:LEP1GSC190 RS06775
gene id: 1192864:LEP1GSC190_RS06775
uniprot id: A0A3Q9DSM6
names: Similarity
messages: Belongs to the peptidase S41A family.

1192864:LEP1GSC190 RS10265
gene id: 1192864:LEP1GSC190_RS10265
uniprot id: A0A3Q9DU18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS05995
gene id: 1192864:LEP1GSC190_RS05995
uniprot id: A0A3Q9DUH1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1192864:LEP1GSC190 RS11650
gene id: 1192864:LEP1GSC190_RS11650
uniprot id: A0A3Q9DVV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1192864:LEP1GSC190 RS09175
gene id: 1192864:LEP1GSC190_RS09175
uniprot id: A0A3Q9DUW8
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS18335
gene id: 1192864:LEP1GSC190_RS18335
uniprot id: A0A3Q9DXM3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1192864:LEP1GSC190 RS13415
gene id: 1192864:LEP1GSC190_RS13415
uniprot id: A0A3Q9DWB5
names: Subcellular Location Annotation
messages: Periplasmic flagellum

1192864:LEP1GSC190 RS13465
gene id: 1192864:LEP1GSC190_RS13465
uniprot id: A0A3Q9DUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1192864:LEP1GSC190 RS06795
gene id: 1192864:LEP1GSC190_RS06795
uniprot id: A0A3Q9DU95
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1192864:LEP1GSC190 RS03955
gene id: 1192864:LEP1GSC190_RS03955
uniprot id: A0A3Q9DTS1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1192864:LEP1GSC190 RS00150
gene id: 1192864:LEP1GSC190_RS00150
uniprot id: A0A3Q9DQS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1192864:LEP1GSC190 RS05945
gene id: 1192864:LEP1GSC190_RS05945
uniprot id: A0A3S9KIS6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1192864:LEP1GSC190 RS07940
gene id: 1192864:LEP1GSC190_RS07940
uniprot id: A0A3Q9DUR5
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS16980
gene id: 1192864:LEP1GSC190_RS16980
uniprot id: A0A3Q9DWF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS09525
gene id: 1192864:LEP1GSC190_RS09525
uniprot id: A0A3Q9DV04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1192864:LEP1GSC190 RS04570
gene id: 1192864:LEP1GSC190_RS04570
uniprot id: A0A3Q9DTX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1192864:LEP1GSC190 RS16910
gene id: 1192864:LEP1GSC190_RS16910
uniprot id: A0A3Q9DX83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1192864:LEP1GSC190 RS18430
gene id: 1192864:LEP1GSC190_RS18430
uniprot id: A0A3S9KQS1
names: Similarity
messages: Belongs to the peptidase S16 family.

1192864:LEP1GSC190 RS02165
gene id: 1192864:LEP1GSC190_RS02165
uniprot id: A0A3Q9DS10
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1192864:LEP1GSC190 RS09685
gene id: 1192864:LEP1GSC190_RS09685
uniprot id: A0A3S9KKN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1192864:LEP1GSC190 RS09135
gene id: 1192864:LEP1GSC190_RS09135
uniprot id: A0A3S9KKF8
names: Similarity
messages: Belongs to the peptidase U62 family.

1192864:LEP1GSC190 RS03225
gene id: 1192864:LEP1GSC190_RS03225
uniprot id: A0A3S9KHJ5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1192864:LEP1GSC190 RS02385
gene id: 1192864:LEP1GSC190_RS02385
uniprot id: A0A3S9KH93
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS02310
gene id: 1192864:LEP1GSC190_RS02310
uniprot id: A0A3S9KH53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1192864:LEP1GSC190 RS06415
gene id: 1192864:LEP1GSC190_RS06415
uniprot id: A0A3Q9DXW0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1192864:LEP1GSC190 RS15200
gene id: 1192864:LEP1GSC190_RS15200
uniprot id: A0A3S9KN89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1192864:LEP1GSC190 RS13410
gene id: 1192864:LEP1GSC190_RS13410
uniprot id: A0A3Q9DWC2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1192864:LEP1GSC190 RS18635
gene id: 1192864:LEP1GSC190_RS18635
uniprot id: A0A3S9KQU4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1192864:LEP1GSC190 RS10685
gene id: 1192864:LEP1GSC190_RS10685
uniprot id: A0A3Q9DTM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS09595
gene id: 1192864:LEP1GSC190_RS09595
uniprot id: A0A3Q9DV99
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS03990
gene id: 1192864:LEP1GSC190_RS03990
uniprot id: A0A3S9KHX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1192864:LEP1GSC190 RS02665
gene id: 1192864:LEP1GSC190_RS02665
uniprot id: A0A3Q9DST7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1192864:LEP1GSC190 RS16590
gene id: 1192864:LEP1GSC190_RS16590
uniprot id: A0A3S9KNX2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS08440
gene id: 1192864:LEP1GSC190_RS08440
uniprot id: A0A3S9KK46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1192864:LEP1GSC190 RS00455
gene id: 1192864:LEP1GSC190_RS00455
uniprot id: A0A3S9KG77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1192864:LEP1GSC190 RS10145
gene id: 1192864:LEP1GSC190_RS10145
uniprot id: A0A3Q9DV79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1192864:LEP1GSC190 RS04860
gene id: 1192864:LEP1GSC190_RS04860
uniprot id: A0A3Q9DTB7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1192864:LEP1GSC190 RS18870
gene id: 1192864:LEP1GSC190_RS18870
uniprot id: A0A3S9KQX2
names: Similarity
messages: Belongs to the pyruvate kinase family.

1192864:LEP1GSC190 RS15070
gene id: 1192864:LEP1GSC190_RS15070
uniprot id: A0A3Q9DW52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1192864:LEP1GSC190 RS12235
gene id: 1192864:LEP1GSC190_RS12235
uniprot id: A0A3Q9DW13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1192864:LEP1GSC190 RS03200
gene id: 1192864:LEP1GSC190_RS03200
uniprot id: A0A3Q9DXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS16955
gene id: 1192864:LEP1GSC190_RS16955
uniprot id: A0A3S9KP18
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1192864:LEP1GSC190 RS14675
gene id: 1192864:LEP1GSC190_RS14675
uniprot id: A0A3Q9DV70
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS07075
gene id: 1192864:LEP1GSC190_RS07075
uniprot id: A0A3Q9DUK8
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS02900
gene id: 1192864:LEP1GSC190_RS02900
uniprot id: A0A3S9KPH5
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS15140
gene id: 1192864:LEP1GSC190_RS15140
uniprot id: A0A3S9KN88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1192864:LEP1GSC190 RS09645
gene id: 1192864:LEP1GSC190_RS09645
uniprot id: A0A3Q9DVH2
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS03060
gene id: 1192864:LEP1GSC190_RS03060
uniprot id: A0A3S9KHH2
names: Similarity
messages: Belongs to the aspartokinase family.

1192864:LEP1GSC190 RS06980
gene id: 1192864:LEP1GSC190_RS06980
uniprot id: A0A3S9KJE1
names: Similarity
messages: Belongs to the NodU/CmcH family.

1192864:LEP1GSC190 RS03980
gene id: 1192864:LEP1GSC190_RS03980
uniprot id: A0A3Q9DS20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1192864:LEP1GSC190 RS14630
gene id: 1192864:LEP1GSC190_RS14630
uniprot id: A0A3Q9DVU4
names: Similarity
messages: Belongs to the threonine synthase family.

1192864:LEP1GSC190 RS03605
gene id: 1192864:LEP1GSC190_RS03605
uniprot id: A0A3Q9DXI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1192864:LEP1GSC190 RS04730
gene id: 1192864:LEP1GSC190_RS04730
uniprot id: A0A3Q9DTS6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1192864:LEP1GSC190 RS10640
gene id: 1192864:LEP1GSC190_RS10640
uniprot id: A0A3Q9DUX6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS09700
gene id: 1192864:LEP1GSC190_RS09700
uniprot id: A0A3Q9DTD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1192864:LEP1GSC190 RS04630
gene id: 1192864:LEP1GSC190_RS04630
uniprot id: A0A3S9KIA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1192864:LEP1GSC190 RS18680
gene id: 1192864:LEP1GSC190_RS18680
uniprot id: A0A3Q9DYB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1192864:LEP1GSC190 RS06530
gene id: 1192864:LEP1GSC190_RS06530
uniprot id: A0A3Q9DTR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1192864:LEP1GSC190 RS15115
gene id: 1192864:LEP1GSC190_RS15115
uniprot id: A0A3Q9DWH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1192864:LEP1GSC190 RS07335
gene id: 1192864:LEP1GSC190_RS07335
uniprot id: A0A3Q9DUM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1192864:LEP1GSC190 RS13565
gene id: 1192864:LEP1GSC190_RS13565
uniprot id: A0A3Q9DVR4
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS07205
gene id: 1192864:LEP1GSC190_RS07205
uniprot id: A0A3S9KJF7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1192864:LEP1GSC190 RS14075
gene id: 1192864:LEP1GSC190_RS14075
uniprot id: A0A3S9KMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS09785
gene id: 1192864:LEP1GSC190_RS09785
uniprot id: A0A3S9KKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

1192864:LEP1GSC190 RS08905
gene id: 1192864:LEP1GSC190_RS08905
uniprot id: A0A3Q9DUC3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS02070
gene id: 1192864:LEP1GSC190_RS02070
uniprot id: A0A3Q9DSQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1192864:LEP1GSC190 RS03680
gene id: 1192864:LEP1GSC190_RS03680
uniprot id: A0A3Q9DTJ4
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1192864:LEP1GSC190 RS18470
gene id: 1192864:LEP1GSC190_RS18470
uniprot id: A0A3Q9DY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1192864:LEP1GSC190 RS03090
gene id: 1192864:LEP1GSC190_RS03090
uniprot id: A0A3S9KHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1192864:LEP1GSC190 RS04255
gene id: 1192864:LEP1GSC190_RS04255
uniprot id: A0A3S9KI14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1192864:LEP1GSC190 RS00620
gene id: 1192864:LEP1GSC190_RS00620
uniprot id: A0A3Q9DSG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1192864:LEP1GSC190 RS07690
gene id: 1192864:LEP1GSC190_RS07690
uniprot id: A0A3S9KJN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1192864:LEP1GSC190 RS12950
gene id: 1192864:LEP1GSC190_RS12950
uniprot id: A0A3S9KM57
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1192864:LEP1GSC190 RS10050
gene id: 1192864:LEP1GSC190_RS10050
uniprot id: A0A3Q9DTG7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS01865
gene id: 1192864:LEP1GSC190_RS01865
uniprot id: A0A3Q9DTD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1192864:LEP1GSC190 RS07495
gene id: 1192864:LEP1GSC190_RS07495
uniprot id: A0A3Q9DUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1192864:LEP1GSC190 RS18375
gene id: 1192864:LEP1GSC190_RS18375
uniprot id: A0A3S9KQQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1192864:LEP1GSC190 RS01685
gene id: 1192864:LEP1GSC190_RS01685
uniprot id: A0A3Q9DRV6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1192864:LEP1GSC190 RS10360
gene id: 1192864:LEP1GSC190_RS10360
uniprot id: A0A3Q9DVJ8
names: Cofactor
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

1192864:LEP1GSC190 RS18320
gene id: 1192864:LEP1GSC190_RS18320
uniprot id: A0A3S9KQM5
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS07255
gene id: 1192864:LEP1GSC190_RS07255
uniprot id: A0A3S9KJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1192864:LEP1GSC190 RS12365
gene id: 1192864:LEP1GSC190_RS12365
uniprot id: A0A3S9KLW3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS10035
gene id: 1192864:LEP1GSC190_RS10035
uniprot id: A0A3Q9DVD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1192864:LEP1GSC190 RS04775
gene id: 1192864:LEP1GSC190_RS04775
uniprot id: A0A3Q9DTA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1192864:LEP1GSC190 RS01075
gene id: 1192864:LEP1GSC190_RS01075
uniprot id: A0A3S9KGJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS00200
gene id: 1192864:LEP1GSC190_RS00200
uniprot id: A0A3S9KG39
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1192864:LEP1GSC190 RS02210
gene id: 1192864:LEP1GSC190_RS02210
uniprot id: A0A3Q9DTF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1192864:LEP1GSC190 RS02905
gene id: 1192864:LEP1GSC190_RS02905
uniprot id: A0A3Q9DSU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1192864:LEP1GSC190 RS09060
gene id: 1192864:LEP1GSC190_RS09060
uniprot id: A0A3S9KKA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1192864:LEP1GSC190 RS08970
gene id: 1192864:LEP1GSC190_RS08970
uniprot id: A0A3Q9DT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS06125
gene id: 1192864:LEP1GSC190_RS06125
uniprot id: A0A3S9KIX3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1192864:LEP1GSC190 RS15265
gene id: 1192864:LEP1GSC190_RS15265
uniprot id: A0A3S9KNC9
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS11365
gene id: 1192864:LEP1GSC190_RS11365
uniprot id: A0A3Q9DV42
names: Similarity
messages: Belongs to the RecJ family.

1192864:LEP1GSC190 RS00615
gene id: 1192864:LEP1GSC190_RS00615
uniprot id: A0A3Q9DSZ1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1192864:LEP1GSC190 RS06655
gene id: 1192864:LEP1GSC190_RS06655
uniprot id: A0A3Q9DSL8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS14990
gene id: 1192864:LEP1GSC190_RS14990
uniprot id: A0A3S9KQ58
names: Similarity
messages: Belongs to the UPF0162 family.

1192864:LEP1GSC190 RS10285
gene id: 1192864:LEP1GSC190_RS10285
uniprot id: A0A3Q9DVL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1192864:LEP1GSC190 RS13345
gene id: 1192864:LEP1GSC190_RS13345
uniprot id: A0A3Q9DU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1192864:LEP1GSC190 RS12265
gene id: 1192864:LEP1GSC190_RS12265
uniprot id: A0A3Q9DVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1192864:LEP1GSC190 RS13965
gene id: 1192864:LEP1GSC190_RS13965
uniprot id: A0A3S9KQ41
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS11045
gene id: 1192864:LEP1GSC190_RS11045
uniprot id: A0A3Q9DVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1192864:LEP1GSC190 RS02875
gene id: 1192864:LEP1GSC190_RS02875
uniprot id: A0A3Q9DTM0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1192864:LEP1GSC190 RS17180
gene id: 1192864:LEP1GSC190_RS17180
uniprot id: A0A3Q9DV58
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS18650
gene id: 1192864:LEP1GSC190_RS18650
uniprot id: A0A3Q9DYD8
names: Similarity
messages: Belongs to the glutamate synthase family.

1192864:LEP1GSC190 RS11575
gene id: 1192864:LEP1GSC190_RS11575
uniprot id: A0A3Q9DVT8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1192864:LEP1GSC190 RS15355
gene id: 1192864:LEP1GSC190_RS15355
uniprot id: A0A3Q9DVE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1192864:LEP1GSC190 RS05975
gene id: 1192864:LEP1GSC190_RS05975
uniprot id: A0A3Q9DST6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1192864:LEP1GSC190 RS09720
gene id: 1192864:LEP1GSC190_RS09720
uniprot id: A0A3Q9DTW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1192864:LEP1GSC190 RS08995
gene id: 1192864:LEP1GSC190_RS08995
uniprot id: A0A3Q9DUD3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1192864:LEP1GSC190 RS03965
gene id: 1192864:LEP1GSC190_RS03965
uniprot id: A0A3S9KHW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1192864:LEP1GSC190 RS13780
gene id: 1192864:LEP1GSC190_RS13780
uniprot id: A0A3Q9DVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

1192864:LEP1GSC190 RS13925
gene id: 1192864:LEP1GSC190_RS13925
uniprot id: A0A3Q9DWF9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1192864:LEP1GSC190 RS02735
gene id: 1192864:LEP1GSC190_RS02735
uniprot id: A0A3Q9DXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS04620
gene id: 1192864:LEP1GSC190_RS04620
uniprot id: A0A3Q9DU22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1192864:LEP1GSC190 RS10365
gene id: 1192864:LEP1GSC190_RS10365
uniprot id: A0A3S9KKZ2
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1192864:LEP1GSC190 RS02465
gene id: 1192864:LEP1GSC190_RS02465
uniprot id: A0A3Q9DSS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1192864:LEP1GSC190 RS11710
gene id: 1192864:LEP1GSC190_RS11710
uniprot id: A0A3Q9DVY5
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS10730
gene id: 1192864:LEP1GSC190_RS10730
uniprot id: A0A3Q9DVP2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1192864:LEP1GSC190 RS03620
gene id: 1192864:LEP1GSC190_RS03620
uniprot id: A0A3S9KHS3
names: Similarity
messages: Belongs to the UPF0234 family.

1192864:LEP1GSC190 RS08060
gene id: 1192864:LEP1GSC190_RS08060
uniprot id: A0A3S9KJU0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1192864:LEP1GSC190 RS08095
gene id: 1192864:LEP1GSC190_RS08095
uniprot id: A0A3S9KJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

1192864:LEP1GSC190 RS09985
gene id: 1192864:LEP1GSC190_RS09985
uniprot id: A0A3Q9DUP4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1192864:LEP1GSC190 RS18725
gene id: 1192864:LEP1GSC190_RS18725
uniprot id: A0A3S9KR18
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1192864:LEP1GSC190 RS18145
gene id: 1192864:LEP1GSC190_RS18145
uniprot id: A0A3Q9DVW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1192864:LEP1GSC190 RS10350
gene id: 1192864:LEP1GSC190_RS10350
uniprot id: A0A3Q9DUT5
names: Similarity
messages: Belongs to the catalase family.

1192864:LEP1GSC190 RS15155
gene id: 1192864:LEP1GSC190_RS15155
uniprot id: A0A3Q9DW61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1192864:LEP1GSC190 RS12940
gene id: 1192864:LEP1GSC190_RS12940
uniprot id: A0A3S9KM72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1192864:LEP1GSC190 RS04150
gene id: 1192864:LEP1GSC190_RS04150
uniprot id: A0A3S9KHZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS15840
gene id: 1192864:LEP1GSC190_RS15840
uniprot id: A0A3Q9DUU2
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1192864:LEP1GSC190 RS18085
gene id: 1192864:LEP1GSC190_RS18085
uniprot id: A0A3Q9DYC7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1192864:LEP1GSC190 RS11955
gene id: 1192864:LEP1GSC190_RS11955
uniprot id: A0A3S9KLS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS15195
gene id: 1192864:LEP1GSC190_RS15195
uniprot id: A0A3Q9DWT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1192864:LEP1GSC190 RS12675
gene id: 1192864:LEP1GSC190_RS12675
uniprot id: A0A3Q9DW97
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1192864:LEP1GSC190 RS13390
gene id: 1192864:LEP1GSC190_RS13390
uniprot id: A0A3Q9DX73
names: Similarity
messages: Belongs to the peptidase S33 family.

1192864:LEP1GSC190 RS12380
gene id: 1192864:LEP1GSC190_RS12380
uniprot id: A0A3Q9DU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1192864:LEP1GSC190 RS09530
gene id: 1192864:LEP1GSC190_RS09530
uniprot id: A0A3Q9DVG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1192864:LEP1GSC190 RS14240
gene id: 1192864:LEP1GSC190_RS14240
uniprot id: A0A3Q9DWM5
names: Similarity
messages: Belongs to the SufE family.

1192864:LEP1GSC190 RS15910
gene id: 1192864:LEP1GSC190_RS15910
uniprot id: A0A3S9KNM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1192864:LEP1GSC190 RS06610
gene id: 1192864:LEP1GSC190_RS06610
uniprot id: A0A3Q9DUG7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS09250
gene id: 1192864:LEP1GSC190_RS09250
uniprot id: A0A3S9KKI3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1192864:LEP1GSC190 RS09855
gene id: 1192864:LEP1GSC190_RS09855
uniprot id: A0A3Q9DVJ3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1192864:LEP1GSC190 RS05740
gene id: 1192864:LEP1GSC190_RS05740
uniprot id: A0A3Q9DU96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1192864:LEP1GSC190 RS03685
gene id: 1192864:LEP1GSC190_RS03685
uniprot id: A0A3Q9DRZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1192864:LEP1GSC190 RS07795
gene id: 1192864:LEP1GSC190_RS07795
uniprot id: A0A3S9KJQ0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1192864:LEP1GSC190 RS10925
gene id: 1192864:LEP1GSC190_RS10925
uniprot id: A0A3Q9DVM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1192864:LEP1GSC190 RS09215
gene id: 1192864:LEP1GSC190_RS09215
uniprot id: A0A3S9KKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1192864:LEP1GSC190 RS18305
gene id: 1192864:LEP1GSC190_RS18305
uniprot id: A0A3Q9DW49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1192864:LEP1GSC190 RS11510
gene id: 1192864:LEP1GSC190_RS11510
uniprot id: A0A3S9KLI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS12850
gene id: 1192864:LEP1GSC190_RS12850
uniprot id: A0A3Q9DW06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1192864:LEP1GSC190 RS15885
gene id: 1192864:LEP1GSC190_RS15885
uniprot id: A0A3Q9DW55
names: Similarity
messages: Belongs to the Gfa family.

1192864:LEP1GSC190 RS08265
gene id: 1192864:LEP1GSC190_RS08265
uniprot id: A0A3Q9DUS5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1192864:LEP1GSC190 RS00270
gene id: 1192864:LEP1GSC190_RS00270
uniprot id: A0A3S9KG79
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS09225
gene id: 1192864:LEP1GSC190_RS09225
uniprot id: A0A3S9KKD9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1192864:LEP1GSC190 RS11140
gene id: 1192864:LEP1GSC190_RS11140
uniprot id: A0A3Q9DVT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1192864:LEP1GSC190 RS08685
gene id: 1192864:LEP1GSC190_RS08685
uniprot id: A0A3Q9DUR8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1192864:LEP1GSC190 RS17520
gene id: 1192864:LEP1GSC190_RS17520
uniprot id: A0A3Q9DV85
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1192864:LEP1GSC190 RS18730
gene id: 1192864:LEP1GSC190_RS18730
uniprot id: A0A3S9KQX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1192864:LEP1GSC190 RS13790
gene id: 1192864:LEP1GSC190_RS13790
uniprot id: A0A3Q9DWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1192864:LEP1GSC190 RS15895
gene id: 1192864:LEP1GSC190_RS15895
uniprot id: A0A3Q9DWY2
names: Similarity
messages: Belongs to the AHA1 family.

1192864:LEP1GSC190 RS09660
gene id: 1192864:LEP1GSC190_RS09660
uniprot id: A0A3Q9DVE6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1192864:LEP1GSC190 RS08190
gene id: 1192864:LEP1GSC190_RS08190
uniprot id: A0A3Q9DSW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS09450
gene id: 1192864:LEP1GSC190_RS09450
uniprot id: A0A3Q9DVF2
names: Similarity
messages: Belongs to the BolA/IbaG family.

1192864:LEP1GSC190 RS18685
gene id: 1192864:LEP1GSC190_RS18685
uniprot id: A0A3Q9DW15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1192864:LEP1GSC190 RS04475
gene id: 1192864:LEP1GSC190_RS04475
uniprot id: A0A3S9KI51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1192864:LEP1GSC190 RS09790
gene id: 1192864:LEP1GSC190_RS09790
uniprot id: A0A3Q9DUP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

1192864:LEP1GSC190 RS03365
gene id: 1192864:LEP1GSC190_RS03365
uniprot id: A0A3Q9DTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS09285
gene id: 1192864:LEP1GSC190_RS09285
uniprot id: A0A3Q9DV80
names: Similarity
messages: Belongs to the TrpF family.

1192864:LEP1GSC190 RS12660
gene id: 1192864:LEP1GSC190_RS12660
uniprot id: A0A3S9KM33
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1192864:LEP1GSC190 RS14840
gene id: 1192864:LEP1GSC190_RS14840
uniprot id: A0A3Q9DUM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1192864:LEP1GSC190 RS15105
gene id: 1192864:LEP1GSC190_RS15105
uniprot id: A0A3S9KNA2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1192864:LEP1GSC190 RS11690
gene id: 1192864:LEP1GSC190_RS11690
uniprot id: A0A3Q9DUG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS12575
gene id: 1192864:LEP1GSC190_RS12575
uniprot id: A0A3Q9DX65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1192864:LEP1GSC190 RS16850
gene id: 1192864:LEP1GSC190_RS16850
uniprot id: A0A3S9KP00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1192864:LEP1GSC190 RS00540
gene id: 1192864:LEP1GSC190_RS00540
uniprot id: A0A3S9KGA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1192864:LEP1GSC190 RS02660
gene id: 1192864:LEP1GSC190_RS02660
uniprot id: A0A3Q9DXH4
names: Similarity
messages: Belongs to the Dps family.

1192864:LEP1GSC190 RS06900
gene id: 1192864:LEP1GSC190_RS06900
uniprot id: A0A3S9KJA7
names: Similarity
messages: Belongs to the SCO1/2 family.

1192864:LEP1GSC190 RS18215
gene id: 1192864:LEP1GSC190_RS18215
uniprot id: A0A3Q9DYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1192864:LEP1GSC190 RS02400
gene id: 1192864:LEP1GSC190_RS02400
uniprot id: A0A3S9KH60
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1192864:LEP1GSC190 RS12930
gene id: 1192864:LEP1GSC190_RS12930
uniprot id: A0A3S9KM50
names: Similarity
messages: Belongs to the TrpC family.

1192864:LEP1GSC190 RS06015
gene id: 1192864:LEP1GSC190_RS06015
uniprot id: A0A3S9KIT2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1192864:LEP1GSC190 RS07185
gene id: 1192864:LEP1GSC190_RS07185
uniprot id: A0A3S9KJD5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1192864:LEP1GSC190 RS09355
gene id: 1192864:LEP1GSC190_RS09355
uniprot id: A0A3S9KKG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1192864:LEP1GSC190 RS01020
gene id: 1192864:LEP1GSC190_RS01020
uniprot id: A0A3Q9DSW7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1192864:LEP1GSC190 RS05730
gene id: 1192864:LEP1GSC190_RS05730
uniprot id: A0A3Q9DUC1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1192864:LEP1GSC190 RS14865
gene id: 1192864:LEP1GSC190_RS14865
uniprot id: A0A3S9KN65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS13740
gene id: 1192864:LEP1GSC190_RS13740
uniprot id: A0A3Q9DY34
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1192864:LEP1GSC190 RS09635
gene id: 1192864:LEP1GSC190_RS09635
uniprot id: A0A3Q9DV16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1192864:LEP1GSC190 RS10890
gene id: 1192864:LEP1GSC190_RS10890
uniprot id: A0A3Q9DVU5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1192864:LEP1GSC190 RS07760
gene id: 1192864:LEP1GSC190_RS07760
uniprot id: A0A3S9KJN6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1192864:LEP1GSC190 RS02770
gene id: 1192864:LEP1GSC190_RS02770
uniprot id: A0A3S9KHD6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1192864:LEP1GSC190 RS11260
gene id: 1192864:LEP1GSC190_RS11260
uniprot id: A0A3S9KLC1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1192864:LEP1GSC190 RS08050
gene id: 1192864:LEP1GSC190_RS08050
uniprot id: A0A3Q9DUX3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1192864:LEP1GSC190 RS07460
gene id: 1192864:LEP1GSC190_RS07460
uniprot id: A0A3S9KJJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1192864:LEP1GSC190 RS11945
gene id: 1192864:LEP1GSC190_RS11945
uniprot id: A0A3Q9DW05
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS06970
gene id: 1192864:LEP1GSC190_RS06970
uniprot id: A0A3Q9DTW8
names: Similarity
messages: Belongs to the NodU/CmcH family.

1192864:LEP1GSC190 RS08005
gene id: 1192864:LEP1GSC190_RS08005
uniprot id: A0A3Q9DUK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1192864:LEP1GSC190 RS00995
gene id: 1192864:LEP1GSC190_RS00995
uniprot id: A0A3S9KGK4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1192864:LEP1GSC190 RS16310
gene id: 1192864:LEP1GSC190_RS16310
uniprot id: A0A3Q9DX23
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1192864:LEP1GSC190 RS02485
gene id: 1192864:LEP1GSC190_RS02485
uniprot id: A0A3Q9DTD8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1192864:LEP1GSC190 RS02475
gene id: 1192864:LEP1GSC190_RS02475
uniprot id: A0A3Q9DTH1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1192864:LEP1GSC190 RS09045
gene id: 1192864:LEP1GSC190_RS09045
uniprot id: A0A3Q9DT56
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS10725
gene id: 1192864:LEP1GSC190_RS10725
uniprot id: A0A3S9KL34
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1192864:LEP1GSC190 RS06385
gene id: 1192864:LEP1GSC190_RS06385
uniprot id: A0A3S9KJ14
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS06460
gene id: 1192864:LEP1GSC190_RS06460
uniprot id: A0A3S9KJ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1192864:LEP1GSC190 RS13250
gene id: 1192864:LEP1GSC190_RS13250
uniprot id: A0A3S9KMA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1192864:LEP1GSC190 RS10425
gene id: 1192864:LEP1GSC190_RS10425
uniprot id: A0A3Q9DTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1192864:LEP1GSC190 RS06785
gene id: 1192864:LEP1GSC190_RS06785
uniprot id: A0A3S9KPR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS05110
gene id: 1192864:LEP1GSC190_RS05110
uniprot id: A0A3Q9DU83
names: Similarity
messages: Belongs to the UPF0175 family.

1192864:LEP1GSC190 RS07465
gene id: 1192864:LEP1GSC190_RS07465
uniprot id: A0A3Q9DUX4
names: Similarity
messages: Belongs to the CinA family.

1192864:LEP1GSC190 RS00035
gene id: 1192864:LEP1GSC190_RS00035
uniprot id: A0A3S9KG21
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1192864:LEP1GSC190 RS08525
gene id: 1192864:LEP1GSC190_RS08525
uniprot id: A0A3Q9DUB3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1192864:LEP1GSC190 RS07340
gene id: 1192864:LEP1GSC190_RS07340
uniprot id: A0A3Q9DUL4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1192864:LEP1GSC190 RS17040
gene id: 1192864:LEP1GSC190_RS17040
uniprot id: A0A3S9KP31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

1192864:LEP1GSC190 RS16035
gene id: 1192864:LEP1GSC190_RS16035
uniprot id: A0A3Q9DX32
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1192864:LEP1GSC190 RS18360
gene id: 1192864:LEP1GSC190_RS18360
uniprot id: A0A3Q9DXZ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1192864:LEP1GSC190 RS01150
gene id: 1192864:LEP1GSC190_RS01150
uniprot id: A0A3S9KGL0
names: Similarity
messages: Belongs to the LOG family.

1192864:LEP1GSC190 RS03130
gene id: 1192864:LEP1GSC190_RS03130
uniprot id: A0A3S9KHM2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1192864:LEP1GSC190 RS01470
gene id: 1192864:LEP1GSC190_RS01470
uniprot id: A0A3S9KGQ4
names: Similarity
messages: Belongs to the AHA1 family.

1192864:LEP1GSC190 RS03430
gene id: 1192864:LEP1GSC190_RS03430
uniprot id: A0A3Q9DTR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1192864:LEP1GSC190 RS14325
gene id: 1192864:LEP1GSC190_RS14325
uniprot id: A0A3S9KMU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1192864:LEP1GSC190 RS11265
gene id: 1192864:LEP1GSC190_RS11265
uniprot id: A0A3S9KLB9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1192864:LEP1GSC190 RS13710
gene id: 1192864:LEP1GSC190_RS13710
uniprot id: A0A3Q9DXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1192864:LEP1GSC190 RS10975
gene id: 1192864:LEP1GSC190_RS10975
uniprot id: A0A3Q9DTQ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1192864:LEP1GSC190 RS00835
gene id: 1192864:LEP1GSC190_RS00835
uniprot id: A0A3S9KPE1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1192864:LEP1GSC190 RS15150
gene id: 1192864:LEP1GSC190_RS15150
uniprot id: A0A3Q9DWS3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1192864:LEP1GSC190 RS03175
gene id: 1192864:LEP1GSC190_RS03175
uniprot id: A0A3Q9DTR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1192864:LEP1GSC190 RS16585
gene id: 1192864:LEP1GSC190_RS16585
uniprot id: A0A3Q9DX54
names: Similarity
messages: Belongs to the CutA family.

1192864:LEP1GSC190 RS07235
gene id: 1192864:LEP1GSC190_RS07235
uniprot id: A0A3S9KPS5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1192864:LEP1GSC190 RS16245
gene id: 1192864:LEP1GSC190_RS16245
uniprot id: A0A3Q9DWX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS12140
gene id: 1192864:LEP1GSC190_RS12140
uniprot id: A0A3Q9DVU6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1192864:LEP1GSC190 RS18425
gene id: 1192864:LEP1GSC190_RS18425
uniprot id: A0A3Q9DY95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1192864:LEP1GSC190 RS15055
gene id: 1192864:LEP1GSC190_RS15055
uniprot id: A0A3Q9DWT5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1192864:LEP1GSC190 RS03150
gene id: 1192864:LEP1GSC190_RS03150
uniprot id: A0A3Q9DRS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1192864:LEP1GSC190 RS17565
gene id: 1192864:LEP1GSC190_RS17565
uniprot id: A0A3S9KQC5
names: Similarity
messages: Belongs to the ParB family.

1192864:LEP1GSC190 RS10510
gene id: 1192864:LEP1GSC190_RS10510
uniprot id: A0A3S9KKY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1192864:LEP1GSC190 RS08820
gene id: 1192864:LEP1GSC190_RS08820
uniprot id: A0A3Q9DV35
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1192864:LEP1GSC190 RS03065
gene id: 1192864:LEP1GSC190_RS03065
uniprot id: A0A3Q9DTM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1192864:LEP1GSC190 RS16710
gene id: 1192864:LEP1GSC190_RS16710
uniprot id: A0A3Q9DX21
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1192864:LEP1GSC190 RS01445
gene id: 1192864:LEP1GSC190_RS01445
uniprot id: A0A3Q9DSK4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS17295
gene id: 1192864:LEP1GSC190_RS17295
uniprot id: A0A3S9KP82
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1192864:LEP1GSC190 RS00300
gene id: 1192864:LEP1GSC190_RS00300
uniprot id: A0A3Q9DSS5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1192864:LEP1GSC190 RS07600
gene id: 1192864:LEP1GSC190_RS07600
uniprot id: A0A3Q9DUG8
names: Similarity
messages: Belongs to the UPF0235 family.

1192864:LEP1GSC190 RS02910
gene id: 1192864:LEP1GSC190_RS02910
uniprot id: A0A3Q9DTC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1192864:LEP1GSC190 RS00595
gene id: 1192864:LEP1GSC190_RS00595
uniprot id: A0A3S9KGD4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS17825
gene id: 1192864:LEP1GSC190_RS17825
uniprot id: A0A3Q9DXT2
names: Similarity
messages: Belongs to the AHA1 family.

1192864:LEP1GSC190 RS04720
gene id: 1192864:LEP1GSC190_RS04720
uniprot id: A0A3Q9DSL8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS17185
gene id: 1192864:LEP1GSC190_RS17185
uniprot id: A0A3Q9DVY6
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS05330
gene id: 1192864:LEP1GSC190_RS05330
uniprot id: A0A3Q9DU84
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1192864:LEP1GSC190 RS10155
gene id: 1192864:LEP1GSC190_RS10155
uniprot id: A0A3Q9DUR9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1192864:LEP1GSC190 RS00765
gene id: 1192864:LEP1GSC190_RS00765
uniprot id: A0A3Q9DSZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS10080
gene id: 1192864:LEP1GSC190_RS10080
uniprot id: A0A3Q9DVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1192864:LEP1GSC190 RS10250
gene id: 1192864:LEP1GSC190_RS10250
uniprot id: A0A3S9KKX7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS13270
gene id: 1192864:LEP1GSC190_RS13270
uniprot id: A0A3Q9DVZ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1192864:LEP1GSC190 RS04360
gene id: 1192864:LEP1GSC190_RS04360
uniprot id: A0A3Q9DXR2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1192864:LEP1GSC190 RS04685
gene id: 1192864:LEP1GSC190_RS04685
uniprot id: A0A3Q9DTX9
names: Similarity
messages: Belongs to the CapA family.

1192864:LEP1GSC190 RS07595
gene id: 1192864:LEP1GSC190_RS07595
uniprot id: A0A3S9KJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1192864:LEP1GSC190 RS14000
gene id: 1192864:LEP1GSC190_RS14000
uniprot id: A0A3S9KMP9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1192864:LEP1GSC190 RS13445
gene id: 1192864:LEP1GSC190_RS13445
uniprot id: A0A3Q9DW63
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1192864:LEP1GSC190 RS00750
gene id: 1192864:LEP1GSC190_RS00750
uniprot id: A0A3Q9DT40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1192864:LEP1GSC190 RS15905
gene id: 1192864:LEP1GSC190_RS15905
uniprot id: A0A3Q9DWX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1192864:LEP1GSC190 RS12255
gene id: 1192864:LEP1GSC190_RS12255
uniprot id: A0A3S9KLT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS11005
gene id: 1192864:LEP1GSC190_RS11005
uniprot id: A0A3Q9DUY4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS03145
gene id: 1192864:LEP1GSC190_RS03145
uniprot id: A0A3Q9DTE1
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1192864:LEP1GSC190 RS05615
gene id: 1192864:LEP1GSC190_RS05615
uniprot id: A0A3Q9DTY3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS10720
gene id: 1192864:LEP1GSC190_RS10720
uniprot id: A0A3Q9DUW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1192864:LEP1GSC190 RS05570
gene id: 1192864:LEP1GSC190_RS05570
uniprot id: A0A3S9KIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1192864:LEP1GSC190 RS11695
gene id: 1192864:LEP1GSC190_RS11695
uniprot id: A0A3Q9DW17
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1192864:LEP1GSC190 RS15000
gene id: 1192864:LEP1GSC190_RS15000
uniprot id: A0A3S9KN53
names: Similarity
messages: Belongs to the AHA1 family.

1192864:LEP1GSC190 RS03460
gene id: 1192864:LEP1GSC190_RS03460
uniprot id: A0A3Q9DTH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS16665
gene id: 1192864:LEP1GSC190_RS16665
uniprot id: A0A3Q9DX61
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1192864:LEP1GSC190 RS10905
gene id: 1192864:LEP1GSC190_RS10905
uniprot id: A0A3Q9DUX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1192864:LEP1GSC190 RS18955
gene id: 1192864:LEP1GSC190_RS18955
uniprot id: A0A3Q9DYP8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1192864:LEP1GSC190 RS14145
gene id: 1192864:LEP1GSC190_RS14145
uniprot id: A0A3Q9DWH9
names: Similarity
messages: Belongs to the NodU/CmcH family.

1192864:LEP1GSC190 RS16610
gene id: 1192864:LEP1GSC190_RS16610
uniprot id: A0A3Q9DX11
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1192864:LEP1GSC190 RS09270
gene id: 1192864:LEP1GSC190_RS09270
uniprot id: A0A3Q9DUG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS12215
gene id: 1192864:LEP1GSC190_RS12215
uniprot id: A0A3S9KLV5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS15220
gene id: 1192864:LEP1GSC190_RS15220
uniprot id: A0A3Q9DW71
names: Similarity
messages: Belongs to the pirin family.

1192864:LEP1GSC190 RS00015
gene id: 1192864:LEP1GSC190_RS00015
uniprot id: A0A3S9KG25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1192864:LEP1GSC190 RS04105
gene id: 1192864:LEP1GSC190_RS04105
uniprot id: A0A3Q9DT55
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1192864:LEP1GSC190 RS13350
gene id: 1192864:LEP1GSC190_RS13350
uniprot id: A0A3Q9DXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1192864:LEP1GSC190 RS07380
gene id: 1192864:LEP1GSC190_RS07380
uniprot id: A0A3Q9DUE8
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS00160
gene id: 1192864:LEP1GSC190_RS00160
uniprot id: A0A3S9KG60
names: Subcellular Location Annotation
messages: Cytoplasm

1192864:LEP1GSC190 RS01995
gene id: 1192864:LEP1GSC190_RS01995
uniprot id: A0A3Q9DSP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1192864:LEP1GSC190 RS02655
gene id: 1192864:LEP1GSC190_RS02655
uniprot id: A0A3S9KHB6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1192864:LEP1GSC190 RS14055
gene id: 1192864:LEP1GSC190_RS14055
uniprot id: A0A3S9KMR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1192864:LEP1GSC190 RS15795
gene id: 1192864:LEP1GSC190_RS15795
uniprot id: A0A3Q9DY57
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1192864:LEP1GSC190 RS17415
gene id: 1192864:LEP1GSC190_RS17415
uniprot id: A0A3Q9DWK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1192864:LEP1GSC190 RS09315
gene id: 1192864:LEP1GSC190_RS09315
uniprot id: A0A3S9KKF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS13760
gene id: 1192864:LEP1GSC190_RS13760
uniprot id: A0A3S9KML7
names: Similarity
messages: Belongs to the ribF family.

1192864:LEP1GSC190 RS04790
gene id: 1192864:LEP1GSC190_RS04790
uniprot id: A0A3Q9DU32
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS05695
gene id: 1192864:LEP1GSC190_RS05695
uniprot id: A0A3Q9DSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1192864:LEP1GSC190 RS09295
gene id: 1192864:LEP1GSC190_RS09295
uniprot id: A0A3S9KKF5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1192864:LEP1GSC190 RS08405
gene id: 1192864:LEP1GSC190_RS08405
uniprot id: A0A3S9KJZ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1192864:LEP1GSC190 RS15050
gene id: 1192864:LEP1GSC190_RS15050
uniprot id: A0A3S9KN63
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1192864:LEP1GSC190 RS11230
gene id: 1192864:LEP1GSC190_RS11230
uniprot id: A0A3S9KLD0
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1192864:LEP1GSC190 RS14185
gene id: 1192864:LEP1GSC190_RS14185
uniprot id: A0A3Q9DWC3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1192864:LEP1GSC190 RS18750
gene id: 1192864:LEP1GSC190_RS18750
uniprot id: A0A3Q9DXH8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1192864:LEP1GSC190 RS19210
gene id: 1192864:LEP1GSC190_RS19210
uniprot id: A0A3Q9DW90
names: Similarity
messages: Belongs to the ParB family.

1192864:LEP1GSC190 RS07415
gene id: 1192864:LEP1GSC190_RS07415
uniprot id: A0A3S9KJH3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1192864:LEP1GSC190 RS01750
gene id: 1192864:LEP1GSC190_RS01750
uniprot id: A0A3S9KGW2
names: Similarity
messages: Belongs to the HsdR family.

1192864:LEP1GSC190 RS04195
gene id: 1192864:LEP1GSC190_RS04195
uniprot id: A0A3S9KI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1192864:LEP1GSC190 RS05780
gene id: 1192864:LEP1GSC190_RS05780
uniprot id: A0A3S9KIP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1192864:LEP1GSC190 RS09090
gene id: 1192864:LEP1GSC190_RS09090
uniprot id: A0A3Q9DWX0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1192864:LEP1GSC190 RS02985
gene id: 1192864:LEP1GSC190_RS02985
uniprot id: A0A3Q9DTI8
names: Similarity
messages: Belongs to the FGGY kinase family.

1192864:LEP1GSC190 RS10520
gene id: 1192864:LEP1GSC190_RS10520
uniprot id: A0A3Q9DTL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1192864:LEP1GSC190 RS09260
gene id: 1192864:LEP1GSC190_RS09260
uniprot id: A0A3Q9DVD6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1192864:LEP1GSC190 RS09130
gene id: 1192864:LEP1GSC190_RS09130
uniprot id: A0A3S9KKC7
names: Similarity
messages: Belongs to the peptidase U62 family.

1192864:LEP1GSC190 RS07345
gene id: 1192864:LEP1GSC190_RS07345
uniprot id: A0A3Q9DU01
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1192864:LEP1GSC190 RS04015
gene id: 1192864:LEP1GSC190_RS04015
uniprot id: A0A3Q9DTI6
names: Similarity
messages: Belongs to the universal stress protein A family.

1192864:LEP1GSC190 RS01255
gene id: 1192864:LEP1GSC190_RS01255
uniprot id: A0A3Q9DSK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS11320
gene id: 1192864:LEP1GSC190_RS11320
uniprot id: A0A3S9KLC9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1192864:LEP1GSC190 RS09475
gene id: 1192864:LEP1GSC190_RS09475
uniprot id: A0A3Q9DVC4
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1192864:LEP1GSC190 RS07165
gene id: 1192864:LEP1GSC190_RS07165
uniprot id: A0A3Q9DUC3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS03440
gene id: 1192864:LEP1GSC190_RS03440
uniprot id: A0A3Q9DTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Membrane

1192864:LEP1GSC190 RS06240
gene id: 1192864:LEP1GSC190_RS06240
uniprot id: A0A3Q9DTP3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1192864:LEP1GSC190 RS10700
gene id: 1192864:LEP1GSC190_RS10700
uniprot id: A0A3S9KL44
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1192864:LEP1GSC190 RS09125
gene id: 1192864:LEP1GSC190_RS09125
uniprot id: A0A3Q9DV41
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1192864:LEP1GSC190 RS09710
gene id: 1192864:LEP1GSC190_RS09710
uniprot id: A0A3Q9DXW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1192864:LEP1GSC190 RS06065
gene id: 1192864:LEP1GSC190_RS06065
uniprot id: A0A3S9KIU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1192864:LEP1GSC190 RS16860
gene id: 1192864:LEP1GSC190_RS16860
uniprot id: A0A3S9KP10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1192864:LEP1GSC190 RS13795
gene id: 1192864:LEP1GSC190_RS13795
uniprot id: A0A3S9KMM8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1192864:LEP1GSC190 RS09850
gene id: 1192864:LEP1GSC190_RS09850
uniprot id: A0A3S9KKP2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1192864:LEP1GSC190 RS18510
gene id: 1192864:LEP1GSC190_RS18510
uniprot id: A0A3S9KQQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS11550
gene id: 1192864:LEP1GSC190_RS11550
uniprot id: A0A3Q9DW02
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS15090
gene id: 1192864:LEP1GSC190_RS15090
uniprot id: A0A3Q9DWL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1192864:LEP1GSC190 RS10945
gene id: 1192864:LEP1GSC190_RS10945
uniprot id: A0A3S9KL60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1192864:LEP1GSC190 RS13690
gene id: 1192864:LEP1GSC190_RS13690
uniprot id: A0A3S9KMK1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1192864:LEP1GSC190 RS08140
gene id: 1192864:LEP1GSC190_RS08140
uniprot id: A0A3Q9DU42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1192864:LEP1GSC190 RS12550
gene id: 1192864:LEP1GSC190_RS12550
uniprot id: A0A3Q9DW87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1192864:LEP1GSC190 RS05855
gene id: 1192864:LEP1GSC190_RS05855
uniprot id: A0A3S9KIQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS11295
gene id: 1192864:LEP1GSC190_RS11295
uniprot id: A0A3S9KLC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1192864:LEP1GSC190 RS02725
gene id: 1192864:LEP1GSC190_RS02725
uniprot id: A0A3Q9DRM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS12590
gene id: 1192864:LEP1GSC190_RS12590
uniprot id: A0A3S9KM17
names: Similarity
messages: Belongs to the pirin family.

1192864:LEP1GSC190 RS12685
gene id: 1192864:LEP1GSC190_RS12685
uniprot id: A0A3Q9DW60
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1192864:LEP1GSC190 RS05420
gene id: 1192864:LEP1GSC190_RS05420
uniprot id: A0A3S9KPN7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS02740
gene id: 1192864:LEP1GSC190_RS02740
uniprot id: A0A3S9KHC1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS12105
gene id: 1192864:LEP1GSC190_RS12105
uniprot id: A0A3Q9DVY7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS17025
gene id: 1192864:LEP1GSC190_RS17025
uniprot id: A0A3Q9DWN5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS14915
gene id: 1192864:LEP1GSC190_RS14915
uniprot id: A0A3Q9DXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1192864:LEP1GSC190 RS06515
gene id: 1192864:LEP1GSC190_RS06515
uniprot id: A0A3S9KJ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1192864:LEP1GSC190 RS15110
gene id: 1192864:LEP1GSC190_RS15110
uniprot id: A0A3S9KN78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1192864:LEP1GSC190 RS07400
gene id: 1192864:LEP1GSC190_RS07400
uniprot id: A0A3S9KJL0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1192864:LEP1GSC190 RS05610
gene id: 1192864:LEP1GSC190_RS05610
uniprot id: A0A3S9KIP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1192864:LEP1GSC190 RS13570
gene id: 1192864:LEP1GSC190_RS13570
uniprot id: A0A3Q9DW74
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS00970
gene id: 1192864:LEP1GSC190_RS00970
uniprot id: A0A3S9KGI0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1192864:LEP1GSC190 RS06035
gene id: 1192864:LEP1GSC190_RS06035
uniprot id: A0A3Q9DU48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1192864:LEP1GSC190 RS07395
gene id: 1192864:LEP1GSC190_RS07395
uniprot id: A0A3S9KPS8
names: Similarity
messages: Belongs to the CapA family.

1192864:LEP1GSC190 RS07860
gene id: 1192864:LEP1GSC190_RS07860
uniprot id: A0A3S9KJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1192864:LEP1GSC190 RS11135
gene id: 1192864:LEP1GSC190_RS11135
uniprot id: A0A3Q9DUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1192864:LEP1GSC190 RS12895
gene id: 1192864:LEP1GSC190_RS12895
uniprot id: A0A3S9KM71
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.

1192864:LEP1GSC190 RS11040
gene id: 1192864:LEP1GSC190_RS11040
uniprot id: A0A3S9KL99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1192864:LEP1GSC190 RS17055
gene id: 1192864:LEP1GSC190_RS17055
uniprot id: A0A3S9KP48
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS03975
gene id: 1192864:LEP1GSC190_RS03975
uniprot id: A0A3Q9DTL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1192864:LEP1GSC190 RS09230
gene id: 1192864:LEP1GSC190_RS09230
uniprot id: A0A3S9KKE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1192864:LEP1GSC190 RS18975
gene id: 1192864:LEP1GSC190_RS18975
uniprot id: A0A3Q9DW37
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1192864:LEP1GSC190 RS08505
gene id: 1192864:LEP1GSC190_RS08505
uniprot id: A0A3Q9DV05
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1192864:LEP1GSC190 RS16280
gene id: 1192864:LEP1GSC190_RS16280
uniprot id: A0A3Q9DW88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1192864:LEP1GSC190 RS16745
gene id: 1192864:LEP1GSC190_RS16745
uniprot id: A0A3Q9DXF0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1192864:LEP1GSC190 RS02710
gene id: 1192864:LEP1GSC190_RS02710
uniprot id: A0A3Q9DST4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1192864:LEP1GSC190 RS17290
gene id: 1192864:LEP1GSC190_RS17290
uniprot id: A0A3Q9DWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

1192864:LEP1GSC190 RS13240
gene id: 1192864:LEP1GSC190_RS13240
uniprot id: A0A3Q9DVK5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1192864:LEP1GSC190 RS00865
gene id: 1192864:LEP1GSC190_RS00865
uniprot id: A0A3S9KGK6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1192864:LEP1GSC190 RS10825
gene id: 1192864:LEP1GSC190_RS10825
uniprot id: A0A3Q9DVL9
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1192864:LEP1GSC190 RS11355
gene id: 1192864:LEP1GSC190_RS11355
uniprot id: A0A3S9KQ04
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1192864:LEP1GSC190 RS05415
gene id: 1192864:LEP1GSC190_RS05415
uniprot id: A0A3S9KII7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1192864:LEP1GSC190 RS08205
gene id: 1192864:LEP1GSC190_RS08205
uniprot id: A0A3Q9DUM5
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

1192864:LEP1GSC190 RS09845
gene id: 1192864:LEP1GSC190_RS09845
uniprot id: A0A3S9KKU3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1192864:LEP1GSC190 RS06285
gene id: 1192864:LEP1GSC190_RS06285
uniprot id: A0A3S9KJ16
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

1192864:LEP1GSC190 RS08830
gene id: 1192864:LEP1GSC190_RS08830
uniprot id: A0A3S9KK86
names: Similarity
messages: Belongs to the peptidase S49 family.

1192864:LEP1GSC190 RS09370
gene id: 1192864:LEP1GSC190_RS09370
uniprot id: A0A3S9KKI9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1192864:LEP1GSC190 RS07805
gene id: 1192864:LEP1GSC190_RS07805
uniprot id: A0A3S9KJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS13505
gene id: 1192864:LEP1GSC190_RS13505
uniprot id: A0A3Q9DW20
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS10500
gene id: 1192864:LEP1GSC190_RS10500
uniprot id: A0A3Q9DUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1192864:LEP1GSC190 RS01175
gene id: 1192864:LEP1GSC190_RS01175
uniprot id: A0A3S9KGJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1192864:LEP1GSC190 RS09650
gene id: 1192864:LEP1GSC190_RS09650
uniprot id: A0A3Q9DUK9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1192864:LEP1GSC190 RS16740
gene id: 1192864:LEP1GSC190_RS16740
uniprot id: A0A3S9KP16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1192864:LEP1GSC190 RS02395
gene id: 1192864:LEP1GSC190_RS02395
uniprot id: A0A3Q9DS35
names: Similarity
messages: Belongs to the acylphosphatase family.

1192864:LEP1GSC190 RS12425
gene id: 1192864:LEP1GSC190_RS12425
uniprot id: A0A3S9KLZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1192864:LEP1GSC190 RS15135
gene id: 1192864:LEP1GSC190_RS15135
uniprot id: A0A3Q9DWT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1192864:LEP1GSC190 RS06230
gene id: 1192864:LEP1GSC190_RS06230
uniprot id: A0A3Q9DUB9
names: Subcellular Location Annotation
messages: Periplasmic flagellum

1192864:LEP1GSC190 RS18505
gene id: 1192864:LEP1GSC190_RS18505
uniprot id: A0A3Q9DYC5
names: Similarity
messages: Belongs to the peptidase S1C family.

1192864:LEP1GSC190 RS19330
gene id: 1192864:LEP1GSC190_RS19330
uniprot id: A0A3Q9DXZ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS13510
gene id: 1192864:LEP1GSC190_RS13510
uniprot id: A0A3Q9DWG7
names: Similarity
messages: Belongs to the AHA1 family.

1192864:LEP1GSC190 RS16725
gene id: 1192864:LEP1GSC190_RS16725
uniprot id: A0A3Q9DWX6
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

1192864:LEP1GSC190 RS05690
gene id: 1192864:LEP1GSC190_RS05690
uniprot id: A0A3S9KIN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS00675
gene id: 1192864:LEP1GSC190_RS00675
uniprot id: A0A3Q9DV95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1192864:LEP1GSC190 RS17625
gene id: 1192864:LEP1GSC190_RS17625
uniprot id: A0A3Q9DXY0
names: Similarity
messages: Belongs to the AHA1 family.

1192864:LEP1GSC190 RS15125
gene id: 1192864:LEP1GSC190_RS15125
uniprot id: A0A3Q9DWW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1192864:LEP1GSC190 RS08635
gene id: 1192864:LEP1GSC190_RS08635
uniprot id: A0A3Q9DUC2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1192864:LEP1GSC190 RS14590
gene id: 1192864:LEP1GSC190_RS14590
uniprot id: A0A3Q9DW01
names: Similarity
messages: Belongs to the citrate synthase family.

1192864:LEP1GSC190 RS08835
gene id: 1192864:LEP1GSC190_RS08835
uniprot id: A0A3Q9DUE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1192864:LEP1GSC190 RS03395
gene id: 1192864:LEP1GSC190_RS03395
uniprot id: A0A3S9KHM9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1192864:LEP1GSC190 RS16090
gene id: 1192864:LEP1GSC190_RS16090
uniprot id: A0A3Q9DWQ1
names: Similarity
messages: Belongs to the phosphopentomutase family.

1192864:LEP1GSC190 RS02750
gene id: 1192864:LEP1GSC190_RS02750
uniprot id: A0A3Q9DT73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1192864:LEP1GSC190 RS09500
gene id: 1192864:LEP1GSC190_RS09500
uniprot id: A0A3Q9DV89
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1192864:LEP1GSC190 RS15925
gene id: 1192864:LEP1GSC190_RS15925
uniprot id: A0A3Q9DWU5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1192864:LEP1GSC190 RS11535
gene id: 1192864:LEP1GSC190_RS11535
uniprot id: A0A3S9KLH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1192864:LEP1GSC190 RS07580
gene id: 1192864:LEP1GSC190_RS07580
uniprot id: A0A3S9KJK0
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

1192864:LEP1GSC190 RS10920
gene id: 1192864:LEP1GSC190_RS10920
uniprot id: A0A3Q9DVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1192864:LEP1GSC190 RS16535
gene id: 1192864:LEP1GSC190_RS16535
uniprot id: A0A3Q9DWV9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1192864:LEP1GSC190 RS15080
gene id: 1192864:LEP1GSC190_RS15080
uniprot id: A0A3S9KN83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1192864:LEP1GSC190 RS18790
gene id: 1192864:LEP1GSC190_RS18790
uniprot id: A0A3S9KQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1192864:LEP1GSC190 RS04080
gene id: 1192864:LEP1GSC190_RS04080
uniprot id: A0A3S9KHY6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1192864:LEP1GSC190 RS11450
gene id: 1192864:LEP1GSC190_RS11450
uniprot id: A0A3S9KLH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1192864:LEP1GSC190 RS10915
gene id: 1192864:LEP1GSC190_RS10915
uniprot id: A0A3S9KL65
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1192864:LEP1GSC190 RS06690
gene id: 1192864:LEP1GSC190_RS06690
uniprot id: A0A3Q9DU86
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1192864:LEP1GSC190 RS04465
gene id: 1192864:LEP1GSC190_RS04465
uniprot id: A0A3Q9DTY2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1192864:LEP1GSC190 RS07310
gene id: 1192864:LEP1GSC190_RS07310
uniprot id: A0A3Q9DUQ9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1192864:LEP1GSC190 RS13365
gene id: 1192864:LEP1GSC190_RS13365
uniprot id: A0A3S9KMC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1192864:LEP1GSC190 RS09455
gene id: 1192864:LEP1GSC190_RS09455
uniprot id: A0A3S9KKI7
names: Similarity
messages: Belongs to the BolA/IbaG family.

1192864:LEP1GSC190 RS08345
gene id: 1192864:LEP1GSC190_RS08345
uniprot id: A0A3S9KJY1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1192864:LEP1GSC190 RS02195
gene id: 1192864:LEP1GSC190_RS02195
uniprot id: A0A3S9KH33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS03610
gene id: 1192864:LEP1GSC190_RS03610
uniprot id: A0A3S9KHR1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1192864:LEP1GSC190 RS09070
gene id: 1192864:LEP1GSC190_RS09070
uniprot id: A0A3S9KPV9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1192864:LEP1GSC190 RS08825
gene id: 1192864:LEP1GSC190_RS08825
uniprot id: A0A3Q9DV09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1192864:LEP1GSC190 RS13470
gene id: 1192864:LEP1GSC190_RS13470
uniprot id: A0A3S9KMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

1192864:LEP1GSC190 RS01575
gene id: 1192864:LEP1GSC190_RS01575
uniprot id: A0A3Q9DVA5
names: Similarity
messages: Belongs to the AHA1 family.

1192864:LEP1GSC190 RS02860
gene id: 1192864:LEP1GSC190_RS02860
uniprot id: A0A3Q9DSV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1192864:LEP1GSC190 RS08495
gene id: 1192864:LEP1GSC190_RS08495
uniprot id: A0A3S9KK11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1192864:LEP1GSC190 RS13820
gene id: 1192864:LEP1GSC190_RS13820
uniprot id: A0A3S9KMM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1192864:LEP1GSC190 RS05865
gene id: 1192864:LEP1GSC190_RS05865
uniprot id: A0A3S9KIT4
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS11395
gene id: 1192864:LEP1GSC190_RS11395
uniprot id: A0A3S9KLG5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1192864:LEP1GSC190 RS06890
gene id: 1192864:LEP1GSC190_RS06890
uniprot id: A0A3S9KJ89
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS14270
gene id: 1192864:LEP1GSC190_RS14270
uniprot id: A0A3S9KMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1192864:LEP1GSC190 RS10690
gene id: 1192864:LEP1GSC190_RS10690
uniprot id: A0A3Q9DU62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS03220
gene id: 1192864:LEP1GSC190_RS03220
uniprot id: A0A3S9KHJ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS13295
gene id: 1192864:LEP1GSC190_RS13295
uniprot id: A0A3Q9DWB4
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1192864:LEP1GSC190 RS08640
gene id: 1192864:LEP1GSC190_RS08640
uniprot id: A0A3S9KK38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS00480
gene id: 1192864:LEP1GSC190_RS00480
uniprot id: A0A3Q9DT36
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1192864:LEP1GSC190 RS15160
gene id: 1192864:LEP1GSC190_RS15160
uniprot id: A0A3Q9DWL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1192864:LEP1GSC190 RS06800
gene id: 1192864:LEP1GSC190_RS06800
uniprot id: A0A3Q9DUQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1192864:LEP1GSC190 RS08105
gene id: 1192864:LEP1GSC190_RS08105
uniprot id: A0A3Q9DTC9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1192864:LEP1GSC190 RS17545
gene id: 1192864:LEP1GSC190_RS17545
uniprot id: A0A3S9KQB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1192864:LEP1GSC190 RS04395
gene id: 1192864:LEP1GSC190_RS04395
uniprot id: A0A3Q9DTU8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1192864:LEP1GSC190 RS00535
gene id: 1192864:LEP1GSC190_RS00535
uniprot id: A0A3Q9DRG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1192864:LEP1GSC190 RS07620
gene id: 1192864:LEP1GSC190_RS07620
uniprot id: A0A3Q9DU05
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS05880
gene id: 1192864:LEP1GSC190_RS05880
uniprot id: A0A3Q9DTK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1192864:LEP1GSC190 RS06440
gene id: 1192864:LEP1GSC190_RS06440
uniprot id: A0A3S9KJ20
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS08160
gene id: 1192864:LEP1GSC190_RS08160
uniprot id: A0A3S9KJZ7
names: Similarity
messages: Belongs to the sigma-54 factor family.

1192864:LEP1GSC190 RS18195
gene id: 1192864:LEP1GSC190_RS18195
uniprot id: A0A3S9KQM1
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1192864:LEP1GSC190 RS17165
gene id: 1192864:LEP1GSC190_RS17165
uniprot id: A0A3S9KP74
names: Similarity
messages: Belongs to the FrhG family.

1192864:LEP1GSC190 RS13715
gene id: 1192864:LEP1GSC190_RS13715
uniprot id: A0A3Q9DW83
names: Similarity
messages: Belongs to the UPF0473 family.

1192864:LEP1GSC190 RS12755
gene id: 1192864:LEP1GSC190_RS12755
uniprot id: A0A3Q9DUP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1192864:LEP1GSC190 RS18500
gene id: 1192864:LEP1GSC190_RS18500
uniprot id: A0A3S9KQS5
names: Similarity
messages: Belongs to the peptidase S1C family.

1192864:LEP1GSC190 RS00340
gene id: 1192864:LEP1GSC190_RS00340
uniprot id: A0A3Q9DWU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS06910
gene id: 1192864:LEP1GSC190_RS06910
uniprot id: A0A3Q9DT22
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1192864:LEP1GSC190 RS01105
gene id: 1192864:LEP1GSC190_RS01105
uniprot id: A0A3S9KGM5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1192864:LEP1GSC190 RS17215
gene id: 1192864:LEP1GSC190_RS17215
uniprot id: A0A3Q9DVQ3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1192864:LEP1GSC190 RS08195
gene id: 1192864:LEP1GSC190_RS08195
uniprot id: A0A3S9KJY0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1192864:LEP1GSC190 RS09750
gene id: 1192864:LEP1GSC190_RS09750
uniprot id: A0A3Q9DVF5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1192864:LEP1GSC190 RS07420
gene id: 1192864:LEP1GSC190_RS07420
uniprot id: A0A3Q9DUN9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1192864:LEP1GSC190 RS13725
gene id: 1192864:LEP1GSC190_RS13725
uniprot id: A0A3Q9DUX1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1192864:LEP1GSC190 RS14335
gene id: 1192864:LEP1GSC190_RS14335
uniprot id: A0A3S9KQ43
names: Similarity
messages: Belongs to the peptidase S49 family.

1192864:LEP1GSC190 RS10585
gene id: 1192864:LEP1GSC190_RS10585
uniprot id: A0A3Q9DUV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1192864:LEP1GSC190 RS02800
gene id: 1192864:LEP1GSC190_RS02800
uniprot id: A0A3Q9DTG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS04650
gene id: 1192864:LEP1GSC190_RS04650
uniprot id: A0A3S9KI77
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS15175
gene id: 1192864:LEP1GSC190_RS15175
uniprot id: A0A3Q9DVC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1192864:LEP1GSC190 RS07700
gene id: 1192864:LEP1GSC190_RS07700
uniprot id: A0A3S9KJM4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1192864:LEP1GSC190 RS18880
gene id: 1192864:LEP1GSC190_RS18880
uniprot id: A0A3Q9DYN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS03415
gene id: 1192864:LEP1GSC190_RS03415
uniprot id: A0A3Q9DTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1192864:LEP1GSC190 RS00295
gene id: 1192864:LEP1GSC190_RS00295
uniprot id: A0A3S9KG91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS09155
gene id: 1192864:LEP1GSC190_RS09155
uniprot id: A0A3Q9DV11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1192864:LEP1GSC190 RS09010
gene id: 1192864:LEP1GSC190_RS09010
uniprot id: A0A3Q9DV71
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS16045
gene id: 1192864:LEP1GSC190_RS16045
uniprot id: A0A3S9KNL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS12915
gene id: 1192864:LEP1GSC190_RS12915
uniprot id: A0A3Q9DXI0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1192864:LEP1GSC190 RS13335
gene id: 1192864:LEP1GSC190_RS13335
uniprot id: A0A3Q9DVP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1192864:LEP1GSC190 RS08975
gene id: 1192864:LEP1GSC190_RS08975
uniprot id: A0A3S9KK93
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1192864:LEP1GSC190 RS08210
gene id: 1192864:LEP1GSC190_RS08210
uniprot id: A0A3Q9DV27
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1192864:LEP1GSC190 RS08475
gene id: 1192864:LEP1GSC190_RS08475
uniprot id: A0A3Q9DTG9
names: Similarity
messages: Belongs to the Nth/MutY family.

1192864:LEP1GSC190 RS06535
gene id: 1192864:LEP1GSC190_RS06535
uniprot id: A0A3S9KJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1192864:LEP1GSC190 RS11065
gene id: 1192864:LEP1GSC190_RS11065
uniprot id: A0A3S9KLD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS01710
gene id: 1192864:LEP1GSC190_RS01710
uniprot id: A0A3S9KGV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1192864:LEP1GSC190 RS06245
gene id: 1192864:LEP1GSC190_RS06245
uniprot id: A0A3Q9DU69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1192864:LEP1GSC190 RS01940
gene id: 1192864:LEP1GSC190_RS01940
uniprot id: A0A3S9KGZ2
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS07975
gene id: 1192864:LEP1GSC190_RS07975
uniprot id: A0A3Q9DSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1192864:LEP1GSC190 RS15235
gene id: 1192864:LEP1GSC190_RS15235
uniprot id: A0A3Q9DUQ3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1192864:LEP1GSC190 RS14995
gene id: 1192864:LEP1GSC190_RS14995
uniprot id: A0A3S9KN80
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1192864:LEP1GSC190 RS08670
gene id: 1192864:LEP1GSC190_RS08670
uniprot id: A0A3Q9DTJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1192864:LEP1GSC190 RS12020
gene id: 1192864:LEP1GSC190_RS12020
uniprot id: A0A3Q9DW45
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1192864:LEP1GSC190 RS14600
gene id: 1192864:LEP1GSC190_RS14600
uniprot id: A0A3Q9DWG5
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS17275
gene id: 1192864:LEP1GSC190_RS17275
uniprot id: A0A3S9KP89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1192864:LEP1GSC190 RS07490
gene id: 1192864:LEP1GSC190_RS07490
uniprot id: A0A3S9KJK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1192864:LEP1GSC190 RS10485
gene id: 1192864:LEP1GSC190_RS10485
uniprot id: A0A3S9KL16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1192864:LEP1GSC190 RS14550
gene id: 1192864:LEP1GSC190_RS14550
uniprot id: A0A3S9KMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1192864:LEP1GSC190 RS00755
gene id: 1192864:LEP1GSC190_RS00755
uniprot id: A0A3S9KGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1192864:LEP1GSC190 RS01900
gene id: 1192864:LEP1GSC190_RS01900
uniprot id: A0A3S9KH01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS07445
gene id: 1192864:LEP1GSC190_RS07445
uniprot id: A0A3Q9DT82
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1192864:LEP1GSC190 RS01290
gene id: 1192864:LEP1GSC190_RS01290
uniprot id: A0A3S9KGQ0
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS12350
gene id: 1192864:LEP1GSC190_RS12350
uniprot id: A0A3Q9DW07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1192864:LEP1GSC190 RS11385
gene id: 1192864:LEP1GSC190_RS11385
uniprot id: A0A3S9KLD2
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS17495
gene id: 1192864:LEP1GSC190_RS17495
uniprot id: A0A3Q9DXD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1192864:LEP1GSC190 RS02855
gene id: 1192864:LEP1GSC190_RS02855
uniprot id: A0A3Q9DVB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1192864:LEP1GSC190 RS08090
gene id: 1192864:LEP1GSC190_RS08090
uniprot id: A0A3Q9DSW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1192864:LEP1GSC190 RS03495
gene id: 1192864:LEP1GSC190_RS03495
uniprot id: A0A3Q9DW62
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1192864:LEP1GSC190 RS09590
gene id: 1192864:LEP1GSC190_RS09590
uniprot id: A0A3Q9DVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1192864:LEP1GSC190 RS13140
gene id: 1192864:LEP1GSC190_RS13140
uniprot id: A0A3S9KMA8
names: Similarity
messages: Belongs to the citrate synthase family.

1192864:LEP1GSC190 RS05885
gene id: 1192864:LEP1GSC190_RS05885
uniprot id: A0A3Q9DUD1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1192864:LEP1GSC190 RS08045
gene id: 1192864:LEP1GSC190_RS08045
uniprot id: A0A3Q9DU33
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1192864:LEP1GSC190 RS05565
gene id: 1192864:LEP1GSC190_RS05565
uniprot id: A0A3S9KPS6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1192864:LEP1GSC190 RS15310
gene id: 1192864:LEP1GSC190_RS15310
uniprot id: A0A3S9KNE4
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1192864:LEP1GSC190 RS14830
gene id: 1192864:LEP1GSC190_RS14830
uniprot id: A0A3Q9DWN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1192864:LEP1GSC190 RS14425
gene id: 1192864:LEP1GSC190_RS14425
uniprot id: A0A3Q9DWE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1192864:LEP1GSC190 RS18155
gene id: 1192864:LEP1GSC190_RS18155
uniprot id: A0A3S9KQK8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1192864:LEP1GSC190 RS05505
gene id: 1192864:LEP1GSC190_RS05505
uniprot id: A0A3S9KIK8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1192864:LEP1GSC190 RS18235
gene id: 1192864:LEP1GSC190_RS18235
uniprot id: A0A3Q9DY66
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1192864:LEP1GSC190 RS04855
gene id: 1192864:LEP1GSC190_RS04855
uniprot id: A0A3Q9DU64
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1192864:LEP1GSC190 RS10745
gene id: 1192864:LEP1GSC190_RS10745
uniprot id: A0A3Q9DVK9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS11380
gene id: 1192864:LEP1GSC190_RS11380
uniprot id: A0A3S9KLD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1192864:LEP1GSC190 RS18950
gene id: 1192864:LEP1GSC190_RS18950
uniprot id: A0A3S9KR21
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1192864:LEP1GSC190 RS01335
gene id: 1192864:LEP1GSC190_RS01335
uniprot id: A0A3S9KPG8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1192864:LEP1GSC190 RS13080
gene id: 1192864:LEP1GSC190_RS13080
uniprot id: A0A3Q9DWD1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1192864:LEP1GSC190 RS15145
gene id: 1192864:LEP1GSC190_RS15145
uniprot id: A0A3Q9DWV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1192864:LEP1GSC190 RS18285
gene id: 1192864:LEP1GSC190_RS18285
uniprot id: A0A3Q9DYG7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1192864:LEP1GSC190 RS10530
gene id: 1192864:LEP1GSC190_RS10530
uniprot id: A0A3Q9DVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Membrane

1192864:LEP1GSC190 RS05395
gene id: 1192864:LEP1GSC190_RS05395
uniprot id: A0A3Q9DSP6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1192864:LEP1GSC190 RS08805
gene id: 1192864:LEP1GSC190_RS08805
uniprot id: A0A3S9KK67
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1192864:LEP1GSC190 RS07520
gene id: 1192864:LEP1GSC190_RS07520
uniprot id: A0A3S9KJJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1192864:LEP1GSC190 RS02095
gene id: 1192864:LEP1GSC190_RS02095
uniprot id: A0A3S9KH10
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1192864:LEP1GSC190 RS13180
gene id: 1192864:LEP1GSC190_RS13180
uniprot id: A0A3Q9DUT1
names: Similarity
messages: Belongs to the glutamate synthase family.

1192864:LEP1GSC190 RS04075
gene id: 1192864:LEP1GSC190_RS04075
uniprot id: A0A3Q9DW67
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1192864:LEP1GSC190 RS06075
gene id: 1192864:LEP1GSC190_RS06075
uniprot id: A0A3S9KIV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1192864:LEP1GSC190 RS16600
gene id: 1192864:LEP1GSC190_RS16600
uniprot id: A0A3S9KNW5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1192864:LEP1GSC190 RS05940
gene id: 1192864:LEP1GSC190_RS05940
uniprot id: A0A3Q9DU37
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1192864:LEP1GSC190 RS15260
gene id: 1192864:LEP1GSC190_RS15260
uniprot id: A0A3Q9DW12
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1192864:LEP1GSC190 RS03585
gene id: 1192864:LEP1GSC190_RS03585
uniprot id: A0A3Q9DTN9
names: Similarity
messages: Belongs to the TlyA family.

1192864:LEP1GSC190 RS05750
gene id: 1192864:LEP1GSC190_RS05750
uniprot id: A0A3S9KIP9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1192864:LEP1GSC190 RS08135
gene id: 1192864:LEP1GSC190_RS08135
uniprot id: A0A3S9KJU9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS15420
gene id: 1192864:LEP1GSC190_RS15420
uniprot id: A0A3Q9DW22
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1192864:LEP1GSC190 RS15190
gene id: 1192864:LEP1GSC190_RS15190
uniprot id: A0A3Q9DW00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1192864:LEP1GSC190 RS12355
gene id: 1192864:LEP1GSC190_RS12355
uniprot id: A0A3Q9DVC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS12285
gene id: 1192864:LEP1GSC190_RS12285
uniprot id: A0A3S9KLT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1192864:LEP1GSC190 RS18075
gene id: 1192864:LEP1GSC190_RS18075
uniprot id: A0A3S9KQL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1192864:LEP1GSC190 RS00770
gene id: 1192864:LEP1GSC190_RS00770
uniprot id: A0A3Q9DXN6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1192864:LEP1GSC190 RS02995
gene id: 1192864:LEP1GSC190_RS02995
uniprot id: A0A3Q9DTD1
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1192864:LEP1GSC190 RS07830
gene id: 1192864:LEP1GSC190_RS07830
uniprot id: A0A3S9KJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1192864:LEP1GSC190 RS14295
gene id: 1192864:LEP1GSC190_RS14295
uniprot id: A0A3Q9DX82
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1192864:LEP1GSC190 RS09385
gene id: 1192864:LEP1GSC190_RS09385
uniprot id: A0A3Q9DUH4
names: Similarity
messages: Belongs to the peptidase S49 family.

1192864:LEP1GSC190 RS01870
gene id: 1192864:LEP1GSC190_RS01870
uniprot id: A0A3S9KPG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1192864:LEP1GSC190 RS18660
gene id: 1192864:LEP1GSC190_RS18660
uniprot id: A0A3Q9DYE6
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS02000
gene id: 1192864:LEP1GSC190_RS02000
uniprot id: A0A3S9KH26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1192864:LEP1GSC190 RS16500
gene id: 1192864:LEP1GSC190_RS16500
uniprot id: A0A3Q9DXZ8
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS12415
gene id: 1192864:LEP1GSC190_RS12415
uniprot id: A0A3S9KLX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1192864:LEP1GSC190 RS03345
gene id: 1192864:LEP1GSC190_RS03345
uniprot id: A0A3S9KHL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS03970
gene id: 1192864:LEP1GSC190_RS03970
uniprot id: A0A3Q9DT46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1192864:LEP1GSC190 RS17600
gene id: 1192864:LEP1GSC190_RS17600
uniprot id: A0A3Q9DY65
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1192864:LEP1GSC190 RS05920
gene id: 1192864:LEP1GSC190_RS05920
uniprot id: A0A3S9KIS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS06635
gene id: 1192864:LEP1GSC190_RS06635
uniprot id: A0A3S9KJ72
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1192864:LEP1GSC190 RS16300
gene id: 1192864:LEP1GSC190_RS16300
uniprot id: A0A3Q9DX66
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS00905
gene id: 1192864:LEP1GSC190_RS00905
uniprot id: A0A3S9KGG6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1192864:LEP1GSC190 RS01945
gene id: 1192864:LEP1GSC190_RS01945
uniprot id: A0A3Q9DSP4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1192864:LEP1GSC190 RS09580
gene id: 1192864:LEP1GSC190_RS09580
uniprot id: A0A3S9KKP8
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

1192864:LEP1GSC190 RS00230
gene id: 1192864:LEP1GSC190_RS00230
uniprot id: A0A3S9KG74
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1192864:LEP1GSC190 RS14810
gene id: 1192864:LEP1GSC190_RS14810
uniprot id: A0A3Q9DWP5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS09310
gene id: 1192864:LEP1GSC190_RS09310
uniprot id: A0A3S9KKF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS08720
gene id: 1192864:LEP1GSC190_RS08720
uniprot id: A0A3Q9DV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS08230
gene id: 1192864:LEP1GSC190_RS08230
uniprot id: A0A3Q9DUZ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1192864:LEP1GSC190 RS01210
gene id: 1192864:LEP1GSC190_RS01210
uniprot id: A0A3Q9DSU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1192864:LEP1GSC190 RS19275
gene id: 1192864:LEP1GSC190_RS19275
uniprot id: A0A3Q9DXR5
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1192864:LEP1GSC190 RS08225
gene id: 1192864:LEP1GSC190_RS08225
uniprot id: A0A3S9KJX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1192864:LEP1GSC190 RS18980
gene id: 1192864:LEP1GSC190_RS18980
uniprot id: A0A3Q9DWZ1
names: Similarity
messages: Belongs to the ALAD family.

1192864:LEP1GSC190 RS06975
gene id: 1192864:LEP1GSC190_RS06975
uniprot id: A0A3S9KJB2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1192864:LEP1GSC190 RS09350
gene id: 1192864:LEP1GSC190_RS09350
uniprot id: A0A3S9KKK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1192864:LEP1GSC190 RS16975
gene id: 1192864:LEP1GSC190_RS16975
uniprot id: A0A3S9KP29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1192864:LEP1GSC190 RS14845
gene id: 1192864:LEP1GSC190_RS14845
uniprot id: A0A3S9KN38
names: Subcellular Location Annotation
messages: Nucleus

1192864:LEP1GSC190 RS06600
gene id: 1192864:LEP1GSC190_RS06600
uniprot id: A0A3Q9DUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1192864:LEP1GSC190 RS05705
gene id: 1192864:LEP1GSC190_RS05705
uniprot id: A0A3Q9DTZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1192864:LEP1GSC190 RS10490
gene id: 1192864:LEP1GSC190_RS10490
uniprot id: A0A3S9KL05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1192864:LEP1GSC190 RS17485
gene id: 1192864:LEP1GSC190_RS17485
uniprot id: A0A3S9KPB1
names: Similarity
messages: Belongs to the ParB family.

1192864:LEP1GSC190 RS17360
gene id: 1192864:LEP1GSC190_RS17360
uniprot id: A0A3S9KP97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1192864:LEP1GSC190 RS13810
gene id: 1192864:LEP1GSC190_RS13810
uniprot id: A0A3Q9DWD7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS02365
gene id: 1192864:LEP1GSC190_RS02365
uniprot id: A0A3S9KH52
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS08770
gene id: 1192864:LEP1GSC190_RS08770
uniprot id: A0A3Q9DTK2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1192864:LEP1GSC190 RS06290
gene id: 1192864:LEP1GSC190_RS06290
uniprot id: A0A3Q9DXK4
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS14025
gene id: 1192864:LEP1GSC190_RS14025
uniprot id: A0A3Q9DXV9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1192864:LEP1GSC190 RS16250
gene id: 1192864:LEP1GSC190_RS16250
uniprot id: A0A3Q9DUX0
names: Similarity
messages: Belongs to the ycf81 family.

1192864:LEP1GSC190 RS00460
gene id: 1192864:LEP1GSC190_RS00460
uniprot id: A0A3S9KGB3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1192864:LEP1GSC190 RS14710
gene id: 1192864:LEP1GSC190_RS14710
uniprot id: A0A3Q9DVV3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1192864:LEP1GSC190 RS06645
gene id: 1192864:LEP1GSC190_RS06645
uniprot id: A0A3Q9DUB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1192864:LEP1GSC190 RS01705
gene id: 1192864:LEP1GSC190_RS01705
uniprot id: A0A3S9KGU7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1192864:LEP1GSC190 RS10015
gene id: 1192864:LEP1GSC190_RS10015
uniprot id: A0A3S9KKT2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1192864:LEP1GSC190 RS03515
gene id: 1192864:LEP1GSC190_RS03515
uniprot id: A0A3S9KHQ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS06130
gene id: 1192864:LEP1GSC190_RS06130
uniprot id: A0A3Q9DU58
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1192864:LEP1GSC190 RS10955
gene id: 1192864:LEP1GSC190_RS10955
uniprot id: A0A3Q9DVJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1192864:LEP1GSC190 RS03295
gene id: 1192864:LEP1GSC190_RS03295
uniprot id: A0A3Q9DSB9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1192864:LEP1GSC190 RS11930
gene id: 1192864:LEP1GSC190_RS11930
uniprot id: A0A3S9KLT7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS03010
gene id: 1192864:LEP1GSC190_RS03010
uniprot id: A0A3S9KHH4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1192864:LEP1GSC190 RS15205
gene id: 1192864:LEP1GSC190_RS15205
uniprot id: A0A3S9KNC4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.

1192864:LEP1GSC190 RS00860
gene id: 1192864:LEP1GSC190_RS00860
uniprot id: A0A3Q9DWL6
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS17730
gene id: 1192864:LEP1GSC190_RS17730
uniprot id: A0A3Q9DXR8
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS13555
gene id: 1192864:LEP1GSC190_RS13555
uniprot id: A0A3Q9DWB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1192864:LEP1GSC190 RS00140
gene id: 1192864:LEP1GSC190_RS00140
uniprot id: A0A3Q9DSR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1192864:LEP1GSC190 RS10760
gene id: 1192864:LEP1GSC190_RS10760
uniprot id: A0A3Q9DTN2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1192864:LEP1GSC190 RS12385
gene id: 1192864:LEP1GSC190_RS12385
uniprot id: A0A3Q9DUL5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS12530
gene id: 1192864:LEP1GSC190_RS12530
uniprot id: A0A3S9KM21
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1192864:LEP1GSC190 RS02460
gene id: 1192864:LEP1GSC190_RS02460
uniprot id: A0A3Q9DWM2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1192864:LEP1GSC190 RS12395
gene id: 1192864:LEP1GSC190_RS12395
uniprot id: A0A3Q9DVT1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1192864:LEP1GSC190 RS01990
gene id: 1192864:LEP1GSC190_RS01990
uniprot id: A0A3Q9DTA0
names: Similarity
messages: Belongs to the MotB family.

1192864:LEP1GSC190 RS05745
gene id: 1192864:LEP1GSC190_RS05745
uniprot id: A0A3S9KIT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1192864:LEP1GSC190 RS07405
gene id: 1192864:LEP1GSC190_RS07405
uniprot id: A0A3Q9DUR7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1192864:LEP1GSC190 RS18615
gene id: 1192864:LEP1GSC190_RS18615
uniprot id: A0A3Q9DYK6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1192864:LEP1GSC190 RS02240
gene id: 1192864:LEP1GSC190_RS02240
uniprot id: A0A3Q9DT57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1192864:LEP1GSC190 RS16305
gene id: 1192864:LEP1GSC190_RS16305
uniprot id: A0A3S9KNS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1192864:LEP1GSC190 RS15915
gene id: 1192864:LEP1GSC190_RS15915
uniprot id: A0A3S9KNJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1192864:LEP1GSC190 RS09195
gene id: 1192864:LEP1GSC190_RS09195
uniprot id: A0A3S9KKD6
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS04485
gene id: 1192864:LEP1GSC190_RS04485
uniprot id: A0A3S9KI58
names: Similarity
messages: Belongs to the pyruvate kinase family.

1192864:LEP1GSC190 RS05575
gene id: 1192864:LEP1GSC190_RS05575
uniprot id: A0A3S9KPP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS09160
gene id: 1192864:LEP1GSC190_RS09160
uniprot id: A0A3Q9DT65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1192864:LEP1GSC190 RS18515
gene id: 1192864:LEP1GSC190_RS18515
uniprot id: A0A3Q9DYH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS13420
gene id: 1192864:LEP1GSC190_RS13420
uniprot id: A0A3S9KMD3
names: Subcellular Location Annotation
messages: Periplasmic flagellum

1192864:LEP1GSC190 RS17590
gene id: 1192864:LEP1GSC190_RS17590
uniprot id: A0A3Q9DY09
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1192864:LEP1GSC190 RS09390
gene id: 1192864:LEP1GSC190_RS09390
uniprot id: A0A3S9KKK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS04580
gene id: 1192864:LEP1GSC190_RS04580
uniprot id: A0A3Q9DTR5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1192864:LEP1GSC190 RS15075
gene id: 1192864:LEP1GSC190_RS15075
uniprot id: A0A3S9KN76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1192864:LEP1GSC190 RS18205
gene id: 1192864:LEP1GSC190_RS18205
uniprot id: A0A3Q9DY87
names: Similarity
messages: Belongs to the peptidase C1 family.

1192864:LEP1GSC190 RS00760
gene id: 1192864:LEP1GSC190_RS00760
uniprot id: A0A3S9KGG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

1192864:LEP1GSC190 RS09105
gene id: 1192864:LEP1GSC190_RS09105
uniprot id: A0A3S9KKB7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1192864:LEP1GSC190 RS06050
gene id: 1192864:LEP1GSC190_RS06050
uniprot id: A0A3Q9DSU5
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1192864:LEP1GSC190 RS18895
gene id: 1192864:LEP1GSC190_RS18895
uniprot id: A0A3S9KQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1192864:LEP1GSC190 RS10820
gene id: 1192864:LEP1GSC190_RS10820
uniprot id: A0A3Q9DVN1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1192864:LEP1GSC190 RS17190
gene id: 1192864:LEP1GSC190_RS17190
uniprot id: A0A3S9KP72
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS15830
gene id: 1192864:LEP1GSC190_RS15830
uniprot id: A0A3S9KNJ2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1192864:LEP1GSC190 RS12440
gene id: 1192864:LEP1GSC190_RS12440
uniprot id: A0A3S9KLY2
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS06380
gene id: 1192864:LEP1GSC190_RS06380
uniprot id: A0A3Q9DSJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1192864:LEP1GSC190 RS05215
gene id: 1192864:LEP1GSC190_RS05215
uniprot id: A0A3Q9DU83
names: Similarity
messages: Belongs to the UPF0175 family.

1192864:LEP1GSC190 RS09435
gene id: 1192864:LEP1GSC190_RS09435
uniprot id: A0A3Q9DT99
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1192864:LEP1GSC190 RS11560
gene id: 1192864:LEP1GSC190_RS11560
uniprot id: A0A3Q9DVW8
names: Similarity
messages: Belongs to the peptidase M24B family.

1192864:LEP1GSC190 RS10600
gene id: 1192864:LEP1GSC190_RS10600
uniprot id: A0A3Q9DVL5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1192864:LEP1GSC190 RS05355
gene id: 1192864:LEP1GSC190_RS05355
uniprot id: A0A3Q9DU36
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1192864:LEP1GSC190 RS06590
gene id: 1192864:LEP1GSC190_RS06590
uniprot id: A0A3Q9DUN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS15240
gene id: 1192864:LEP1GSC190_RS15240
uniprot id: A0A3Q9DVD7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1192864:LEP1GSC190 RS07425
gene id: 1192864:LEP1GSC190_RS07425
uniprot id: A0A3Q9DUM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS18000
gene id: 1192864:LEP1GSC190_RS18000
uniprot id: A0A3Q9DYB4
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS08940
gene id: 1192864:LEP1GSC190_RS08940
uniprot id: A0A3S9KK87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1192864:LEP1GSC190 RS17940
gene id: 1192864:LEP1GSC190_RS17940
uniprot id: A0A3S9KQI7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS12345
gene id: 1192864:LEP1GSC190_RS12345
uniprot id: A0A3Q9DW23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1192864:LEP1GSC190 RS08235
gene id: 1192864:LEP1GSC190_RS08235
uniprot id: A0A3Q9DUX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1192864:LEP1GSC190 RS02275
gene id: 1192864:LEP1GSC190_RS02275
uniprot id: A0A3Q9DTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1192864:LEP1GSC190 RS03905
gene id: 1192864:LEP1GSC190_RS03905
uniprot id: A0A3Q9DTY3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS18370
gene id: 1192864:LEP1GSC190_RS18370
uniprot id: A0A3S9KQQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1192864:LEP1GSC190 RS02865
gene id: 1192864:LEP1GSC190_RS02865
uniprot id: A0A3S9KHF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1192864:LEP1GSC190 RS15095
gene id: 1192864:LEP1GSC190_RS15095
uniprot id: A0A3Q9DUN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1192864:LEP1GSC190 RS18300
gene id: 1192864:LEP1GSC190_RS18300
uniprot id: A0A3Q9DYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1192864:LEP1GSC190 RS04550
gene id: 1192864:LEP1GSC190_RS04550
uniprot id: A0A3Q9DT87
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1192864:LEP1GSC190 RS02170
gene id: 1192864:LEP1GSC190_RS02170
uniprot id: A0A3S9KH30
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS10220
gene id: 1192864:LEP1GSC190_RS10220
uniprot id: A0A3S9KQI7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1192864:LEP1GSC190 RS04275
gene id: 1192864:LEP1GSC190_RS04275
uniprot id: A0A3S9KI40
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1192864:LEP1GSC190 RS01310
gene id: 1192864:LEP1GSC190_RS01310
uniprot id: A0A3S9KGN4
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS08110
gene id: 1192864:LEP1GSC190_RS08110
uniprot id: A0A3S9KJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1192864:LEP1GSC190 RS04555
gene id: 1192864:LEP1GSC190_RS04555
uniprot id: A0A3Q9DU13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1192864:LEP1GSC190 RS00570
gene id: 1192864:LEP1GSC190_RS00570
uniprot id: A0A3Q9DSG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1192864:LEP1GSC190 RS08410
gene id: 1192864:LEP1GSC190_RS08410
uniprot id: A0A3Q9DV48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1192864:LEP1GSC190 RS02885
gene id: 1192864:LEP1GSC190_RS02885
uniprot id: A0A3Q9DTH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1192864:LEP1GSC190 RS13065
gene id: 1192864:LEP1GSC190_RS13065
uniprot id: A0A3Q9DUS2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1192864:LEP1GSC190 RS13395
gene id: 1192864:LEP1GSC190_RS13395
uniprot id: A0A3Q9DW10
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1192864:LEP1GSC190 RS17965
gene id: 1192864:LEP1GSC190_RS17965
uniprot id: A0A3Q9DXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1192864:LEP1GSC190 RS00920
gene id: 1192864:LEP1GSC190_RS00920
uniprot id: A0A3Q9DSV8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1192864:LEP1GSC190 RS07925
gene id: 1192864:LEP1GSC190_RS07925
uniprot id: A0A3S9KJR7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS11420
gene id: 1192864:LEP1GSC190_RS11420
uniprot id: A0A3S9KLF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1192864:LEP1GSC190 RS08115
gene id: 1192864:LEP1GSC190_RS08115
uniprot id: A0A3S9KJV3
names: Similarity
messages: Belongs to the peptidase C40 family.

1192864:LEP1GSC190 RS15040
gene id: 1192864:LEP1GSC190_RS15040
uniprot id: A0A3S9KQ64
names: Similarity
messages: Belongs to the lipase chaperone family.

1192864:LEP1GSC190 RS07350
gene id: 1192864:LEP1GSC190_RS07350
uniprot id: A0A3Q9DUG9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1192864:LEP1GSC190 RS00780
gene id: 1192864:LEP1GSC190_RS00780
uniprot id: A0A3Q9DSV1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1192864:LEP1GSC190 RS04760
gene id: 1192864:LEP1GSC190_RS04760
uniprot id: A0A3S9KI93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1192864:LEP1GSC190 RS13985
gene id: 1192864:LEP1GSC190_RS13985
uniprot id: A0A3S9KMR3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1192864:LEP1GSC190 RS06870
gene id: 1192864:LEP1GSC190_RS06870
uniprot id: A0A3Q9DUD0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1192864:LEP1GSC190 RS00530
gene id: 1192864:LEP1GSC190_RS00530
uniprot id: A0A3S9KGC6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1192864:LEP1GSC190 RS06520
gene id: 1192864:LEP1GSC190_RS06520
uniprot id: A0A3Q9DUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1192864:LEP1GSC190 RS06025
gene id: 1192864:LEP1GSC190_RS06025
uniprot id: A0A3Q9DU99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1192864:LEP1GSC190 RS08695
gene id: 1192864:LEP1GSC190_RS08695
uniprot id: A0A3S9KK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1192864:LEP1GSC190 RS13940
gene id: 1192864:LEP1GSC190_RS13940
uniprot id: A0A3S9KMM0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1192864:LEP1GSC190 RS01185
gene id: 1192864:LEP1GSC190_RS01185
uniprot id: A0A3S9KGL4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1192864:LEP1GSC190 RS16550
gene id: 1192864:LEP1GSC190_RS16550
uniprot id: A0A3S9KNU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1192864:LEP1GSC190 RS00100
gene id: 1192864:LEP1GSC190_RS00100
uniprot id: A0A3Q9DT03
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1192864:LEP1GSC190 RS16290
gene id: 1192864:LEP1GSC190_RS16290
uniprot id: A0A3Q9DX20
names: Similarity
messages: Belongs to the SCO1/2 family.

1192864:LEP1GSC190 RS02730
gene id: 1192864:LEP1GSC190_RS02730
uniprot id: A0A3Q9DS71
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS14950
gene id: 1192864:LEP1GSC190_RS14950
uniprot id: A0A3S9KN54
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1192864:LEP1GSC190 RS08295
gene id: 1192864:LEP1GSC190_RS08295
uniprot id: A0A3S9KJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS03540
gene id: 1192864:LEP1GSC190_RS03540
uniprot id: A0A3Q9DT10
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS09665
gene id: 1192864:LEP1GSC190_RS09665
uniprot id: A0A3Q9DVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1192864:LEP1GSC190 RS17075
gene id: 1192864:LEP1GSC190_RS17075
uniprot id: A0A3S9KP45
names: Similarity
messages: Belongs to the fructosamine kinase family.

1192864:LEP1GSC190 RS01555
gene id: 1192864:LEP1GSC190_RS01555
uniprot id: A0A3S9KGR7
names: Subcellular Location Annotation
messages: Membrane

1192864:LEP1GSC190 RS18040
gene id: 1192864:LEP1GSC190_RS18040
uniprot id: A0A3Q9DVV1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1192864:LEP1GSC190 RS04590
gene id: 1192864:LEP1GSC190_RS04590
uniprot id: A0A3S9KI66
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1192864:LEP1GSC190 RS04215
gene id: 1192864:LEP1GSC190_RS04215
uniprot id: A0A3S9KI28
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1192864:LEP1GSC190 RS18675
gene id: 1192864:LEP1GSC190_RS18675
uniprot id: A0A3S9KQU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1192864:LEP1GSC190 RS06070
gene id: 1192864:LEP1GSC190_RS06070
uniprot id: A0A3Q9DTM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1192864:LEP1GSC190 RS06475
gene id: 1192864:LEP1GSC190_RS06475
uniprot id: A0A3S9KJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1192864:LEP1GSC190 RS10070
gene id: 1192864:LEP1GSC190_RS10070
uniprot id: A0A3Q9DV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1192864:LEP1GSC190 RS11715
gene id: 1192864:LEP1GSC190_RS11715
uniprot id: A0A3S9KLM1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1192864:LEP1GSC190 RS07410
gene id: 1192864:LEP1GSC190_RS07410
uniprot id: A0A3S9KJI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1192864:LEP1GSC190 RS09280
gene id: 1192864:LEP1GSC190_RS09280
uniprot id: A0A3S9KKF9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1192864:LEP1GSC190 RS08690
gene id: 1192864:LEP1GSC190_RS08690
uniprot id: A0A3S9KK40
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1192864:LEP1GSC190 RS14215
gene id: 1192864:LEP1GSC190_RS14215
uniprot id: A0A3S9KMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1192864:LEP1GSC190 RS17515
gene id: 1192864:LEP1GSC190_RS17515
uniprot id: A0A3Q9DXA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1192864:LEP1GSC190 RS09290
gene id: 1192864:LEP1GSC190_RS09290
uniprot id: A0A3S9KKE4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1192864:LEP1GSC190 RS08900
gene id: 1192864:LEP1GSC190_RS08900
uniprot id: A0A3S9KK98
names: Similarity
messages: Belongs to the enterotoxin A family.

1192864:LEP1GSC190 RS00740
gene id: 1192864:LEP1GSC190_RS00740
uniprot id: A0A3Q9DT50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1192864:LEP1GSC190 RS05915
gene id: 1192864:LEP1GSC190_RS05915
uniprot id: A0A3S9KIS9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1192864:LEP1GSC190 RS02405
gene id: 1192864:LEP1GSC190_RS02405
uniprot id: A0A3S9KPH1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1192864:LEP1GSC190 RS14825
gene id: 1192864:LEP1GSC190_RS14825
uniprot id: A0A3Q9DWS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1192864:LEP1GSC190 RS15775
gene id: 1192864:LEP1GSC190_RS15775
uniprot id: A0A3Q9DX13
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1192864:LEP1GSC190 RS18220
gene id: 1192864:LEP1GSC190_RS18220
uniprot id: A0A3S9KQM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane