1184267:A11Q RS00565
gene id: 1184267:A11Q_RS00565
uniprot id: M4V7C2
names: Similarity
messages: Belongs to the Gfa family.

1184267:A11Q RS05705
gene id: 1184267:A11Q_RS05705
uniprot id: M4V7H9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1184267:A11Q RS04490
gene id: 1184267:A11Q_RS04490
uniprot id: M4V9J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS06865
gene id: 1184267:A11Q_RS06865
uniprot id: M4VC31
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1184267:A11Q RS04520
gene id: 1184267:A11Q_RS04520
uniprot id: M4VAR9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1184267:A11Q RS04705
gene id: 1184267:A11Q_RS04705
uniprot id: M4V7H1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1184267:A11Q RS06665
gene id: 1184267:A11Q_RS06665
uniprot id: M4VBZ8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1184267:A11Q RS02065
gene id: 1184267:A11Q_RS02065
uniprot id: M4V862
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1184267:A11Q RS06365
gene id: 1184267:A11Q_RS06365
uniprot id: M4V7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1184267:A11Q RS03495
gene id: 1184267:A11Q_RS03495
uniprot id: M4V6B7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1184267:A11Q RS11260
gene id: 1184267:A11Q_RS11260
uniprot id: M4VB63
names: Similarity
messages: Belongs to the arginase family.

1184267:A11Q RS11170
gene id: 1184267:A11Q_RS11170
uniprot id: M4VEH5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1184267:A11Q RS12335
gene id: 1184267:A11Q_RS12335
uniprot id: M4VTX6
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS00215
gene id: 1184267:A11Q_RS00215
uniprot id: M4V505
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS00050
gene id: 1184267:A11Q_RS00050
uniprot id: M4V720
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1184267:A11Q RS05525
gene id: 1184267:A11Q_RS05525
uniprot id: M4V7W4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1184267:A11Q RS06930
gene id: 1184267:A11Q_RS06930
uniprot id: M4VAU8
names: Similarity
messages: Belongs to the FBPase class 2 family.

1184267:A11Q RS13075
gene id: 1184267:A11Q_RS13075
uniprot id: M4VUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1184267:A11Q RS03360
gene id: 1184267:A11Q_RS03360
uniprot id: M4V8W4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1184267:A11Q RS03045
gene id: 1184267:A11Q_RS03045
uniprot id: M4V9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1184267:A11Q RS07190
gene id: 1184267:A11Q_RS07190
uniprot id: M4V8V6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1184267:A11Q RS11070
gene id: 1184267:A11Q_RS11070
uniprot id: M4VD50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1184267:A11Q RS06845
gene id: 1184267:A11Q_RS06845
uniprot id: M4V864
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1184267:A11Q RS04045
gene id: 1184267:A11Q_RS04045
uniprot id: M4VAJ0
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS01465
gene id: 1184267:A11Q_RS01465
uniprot id: M4VN66
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1184267:A11Q RS08320
gene id: 1184267:A11Q_RS08320
uniprot id: M4VRQ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1184267:A11Q RS11860
gene id: 1184267:A11Q_RS11860
uniprot id: M4VBI7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1184267:A11Q RS08515
gene id: 1184267:A11Q_RS08515
uniprot id: M4V926
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1184267:A11Q RS13530
gene id: 1184267:A11Q_RS13530
uniprot id: M4VAX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS10620
gene id: 1184267:A11Q_RS10620
uniprot id: M4VAR5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1184267:A11Q RS04075
gene id: 1184267:A11Q_RS04075
uniprot id: M4V6P1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1184267:A11Q RS00770
gene id: 1184267:A11Q_RS00770
uniprot id: M4V4W2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1184267:A11Q RS02725
gene id: 1184267:A11Q_RS02725
uniprot id: M4V9R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1184267:A11Q RS12990
gene id: 1184267:A11Q_RS12990
uniprot id: M4VBM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS05125
gene id: 1184267:A11Q_RS05125
uniprot id: M4V7P4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS13065
gene id: 1184267:A11Q_RS13065
uniprot id: M4VBN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1184267:A11Q RS05430
gene id: 1184267:A11Q_RS05430
uniprot id: M4VQ70
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1184267:A11Q RS07765
gene id: 1184267:A11Q_RS07765
uniprot id: M4VRF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1184267:A11Q RS09520
gene id: 1184267:A11Q_RS09520
uniprot id: M4VSD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1184267:A11Q RS10260
gene id: 1184267:A11Q_RS10260
uniprot id: M4VA21
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1184267:A11Q RS04605
gene id: 1184267:A11Q_RS04605
uniprot id: M4V7F2
names: Similarity
messages: Belongs to the Skp family.

1184267:A11Q RS09180
gene id: 1184267:A11Q_RS09180
uniprot id: M4VDE2
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS01360
gene id: 1184267:A11Q_RS01360
uniprot id: M4V5Q3
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09295
gene id: 1184267:A11Q_RS09295
uniprot id: M4VS97
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS04675
gene id: 1184267:A11Q_RS04675
uniprot id: M4V6Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1184267:A11Q RS10760
gene id: 1184267:A11Q_RS10760
uniprot id: M4VAB8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1184267:A11Q RS02230
gene id: 1184267:A11Q_RS02230
uniprot id: M4V5N1
names: Similarity
messages: Belongs to the SCO1/2 family.

1184267:A11Q RS13925
gene id: 1184267:A11Q_RS13925
uniprot id: M4V9C7
names: Similarity
messages: Belongs to the SUI1 family.

1184267:A11Q RS12890
gene id: 1184267:A11Q_RS12890
uniprot id: M4VFE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS10705
gene id: 1184267:A11Q_RS10705
uniprot id: M4VE72
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS07450
gene id: 1184267:A11Q_RS07450
uniprot id: M4VB47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS13135
gene id: 1184267:A11Q_RS13135
uniprot id: M4VFJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1184267:A11Q RS04085
gene id: 1184267:A11Q_RS04085
uniprot id: M4VPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1184267:A11Q RS11680
gene id: 1184267:A11Q_RS11680
uniprot id: M4VAY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1184267:A11Q RS00940
gene id: 1184267:A11Q_RS00940
uniprot id: M4VMU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1184267:A11Q RS04175
gene id: 1184267:A11Q_RS04175
uniprot id: M4V6Q7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1184267:A11Q RS03675
gene id: 1184267:A11Q_RS03675
uniprot id: M4V6X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1184267:A11Q RS08330
gene id: 1184267:A11Q_RS08330
uniprot id: M4VCW1
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS05255
gene id: 1184267:A11Q_RS05255
uniprot id: M4V7R7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1184267:A11Q RS09990
gene id: 1184267:A11Q_RS09990
uniprot id: M4VAE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1184267:A11Q RS12755
gene id: 1184267:A11Q_RS12755
uniprot id: M4VU56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1184267:A11Q RS02355
gene id: 1184267:A11Q_RS02355
uniprot id: M4V669
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1184267:A11Q RS00290
gene id: 1184267:A11Q_RS00290
uniprot id: M4VMG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1184267:A11Q RS07055
gene id: 1184267:A11Q_RS07055
uniprot id: M4V8A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1184267:A11Q RS09140
gene id: 1184267:A11Q_RS09140
uniprot id: M4VA10
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1184267:A11Q RS02425
gene id: 1184267:A11Q_RS02425
uniprot id: M4V5R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1184267:A11Q RS03925
gene id: 1184267:A11Q_RS03925
uniprot id: M4V6L7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1184267:A11Q RS00875
gene id: 1184267:A11Q_RS00875
uniprot id: M4V8Q4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1184267:A11Q RS06250
gene id: 1184267:A11Q_RS06250
uniprot id: M4VAG3
names: Similarity
messages: Belongs to the DapB family.

1184267:A11Q RS10350
gene id: 1184267:A11Q_RS10350
uniprot id: M4VCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1184267:A11Q RS06710
gene id: 1184267:A11Q_RS06710
uniprot id: M4VAQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1184267:A11Q RS01245
gene id: 1184267:A11Q_RS01245
uniprot id: M4VN31
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1184267:A11Q RS04380
gene id: 1184267:A11Q_RS04380
uniprot id: M4V9H1
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1184267:A11Q RS04285
gene id: 1184267:A11Q_RS04285
uniprot id: M4V9F2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS00825
gene id: 1184267:A11Q_RS00825
uniprot id: M4V4X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184267:A11Q RS09440
gene id: 1184267:A11Q_RS09440
uniprot id: M4VA59
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1184267:A11Q RS09435
gene id: 1184267:A11Q_RS09435
uniprot id: M4V9M3
names: Similarity
messages: Belongs to the CutA family.

1184267:A11Q RS00045
gene id: 1184267:A11Q_RS00045
uniprot id: M4VMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1184267:A11Q RS11380
gene id: 1184267:A11Q_RS11380
uniprot id: M4VAT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1184267:A11Q RS03315
gene id: 1184267:A11Q_RS03315
uniprot id: M4VA29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1184267:A11Q RS04250
gene id: 1184267:A11Q_RS04250
uniprot id: M4V791
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1184267:A11Q RS08475
gene id: 1184267:A11Q_RS08475
uniprot id: M4VRU0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS03280
gene id: 1184267:A11Q_RS03280
uniprot id: M4VA24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1184267:A11Q RS04545
gene id: 1184267:A11Q_RS04545
uniprot id: M4VAS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1184267:A11Q RS02525
gene id: 1184267:A11Q_RS02525
uniprot id: M4V5T9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1184267:A11Q RS00420
gene id: 1184267:A11Q_RS00420
uniprot id: M4V790
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS06905
gene id: 1184267:A11Q_RS06905
uniprot id: M4VAU3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1184267:A11Q RS03905
gene id: 1184267:A11Q_RS03905
uniprot id: M4V733
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1184267:A11Q RS03610
gene id: 1184267:A11Q_RS03610
uniprot id: M4V913
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1184267:A11Q RS07540
gene id: 1184267:A11Q_RS07540
uniprot id: M4VRB1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1184267:A11Q RS07140
gene id: 1184267:A11Q_RS07140
uniprot id: M4VR40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1184267:A11Q RS12570
gene id: 1184267:A11Q_RS12570
uniprot id: M4VBE0
names: Similarity
messages: Belongs to the NodU/CmcH family.

1184267:A11Q RS09490
gene id: 1184267:A11Q_RS09490
uniprot id: M4VA65
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1184267:A11Q RS01875
gene id: 1184267:A11Q_RS01875
uniprot id: M4V5H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS04755
gene id: 1184267:A11Q_RS04755
uniprot id: M4V7I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1184267:A11Q RS10165
gene id: 1184267:A11Q_RS10165
uniprot id: M4VAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS07040
gene id: 1184267:A11Q_RS07040
uniprot id: M4VR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS03485
gene id: 1184267:A11Q_RS03485
uniprot id: M4V8Y9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1184267:A11Q RS00820
gene id: 1184267:A11Q_RS00820
uniprot id: M4V8P6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184267:A11Q RS11655
gene id: 1184267:A11Q_RS11655
uniprot id: M4VAX8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1184267:A11Q RS10960
gene id: 1184267:A11Q_RS10960
uniprot id: M4VAZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1184267:A11Q RS04865
gene id: 1184267:A11Q_RS04865
uniprot id: M4V9R0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1184267:A11Q RS04355
gene id: 1184267:A11Q_RS04355
uniprot id: M4VPN3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1184267:A11Q RS04330
gene id: 1184267:A11Q_RS04330
uniprot id: M4VPN0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1184267:A11Q RS02290
gene id: 1184267:A11Q_RS02290
uniprot id: M4VNJ9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1184267:A11Q RS02385
gene id: 1184267:A11Q_RS02385
uniprot id: M4VNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1184267:A11Q RS04575
gene id: 1184267:A11Q_RS04575
uniprot id: M4V6X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1184267:A11Q RS04270
gene id: 1184267:A11Q_RS04270
uniprot id: M4V6S5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1184267:A11Q RS06835
gene id: 1184267:A11Q_RS06835
uniprot id: M4VAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1184267:A11Q RS03055
gene id: 1184267:A11Q_RS03055
uniprot id: M4V6J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1184267:A11Q RS08440
gene id: 1184267:A11Q_RS08440
uniprot id: M4V9K3
names: Similarity
messages: Belongs to the peptidase C59 family.

1184267:A11Q RS11535
gene id: 1184267:A11Q_RS11535
uniprot id: M4VBD6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Belongs to the spermidine/spermine synthase family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Homodimer or homotetramer.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS02835
gene id: 1184267:A11Q_RS02835
uniprot id: M4VNU0
names: Similarity
messages: Belongs to the FlgM family.

1184267:A11Q RS13505
gene id: 1184267:A11Q_RS13505
uniprot id: M4V8J0
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

1184267:A11Q RS02805
gene id: 1184267:A11Q_RS02805
uniprot id: M4V6F3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1184267:A11Q RS04945
gene id: 1184267:A11Q_RS04945
uniprot id: M4VB00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1184267:A11Q RS04360
gene id: 1184267:A11Q_RS04360
uniprot id: M4V9G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1184267:A11Q RS07295
gene id: 1184267:A11Q_RS07295
uniprot id: M4V8X3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1184267:A11Q RS12950
gene id: 1184267:A11Q_RS12950
uniprot id: M4VU99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1184267:A11Q RS00250
gene id: 1184267:A11Q_RS00250
uniprot id: M4V8E1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS03720
gene id: 1184267:A11Q_RS03720
uniprot id: M4V6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1184267:A11Q RS09600
gene id: 1184267:A11Q_RS09600
uniprot id: M4VCB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1184267:A11Q RS03995
gene id: 1184267:A11Q_RS03995
uniprot id: M4VAI3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS09825
gene id: 1184267:A11Q_RS09825
uniprot id: M4VCF7
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1184267:A11Q RS09100
gene id: 1184267:A11Q_RS09100
uniprot id: M4VC35
names: Similarity
messages: Belongs to the FGGY kinase family.

1184267:A11Q RS02645
gene id: 1184267:A11Q_RS02645
uniprot id: M4V8G1
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS00890
gene id: 1184267:A11Q_RS00890
uniprot id: M4VMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1184267:A11Q RS06375
gene id: 1184267:A11Q_RS06375
uniprot id: M4VQR3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1184267:A11Q RS10155
gene id: 1184267:A11Q_RS10155
uniprot id: M4VDW4
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS00660
gene id: 1184267:A11Q_RS00660
uniprot id: M4VMP3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS09540
gene id: 1184267:A11Q_RS09540
uniprot id: M4VA73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1184267:A11Q RS06685
gene id: 1184267:A11Q_RS06685
uniprot id: M4VAQ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS02755
gene id: 1184267:A11Q_RS02755
uniprot id: M4V5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1184267:A11Q RS09250
gene id: 1184267:A11Q_RS09250
uniprot id: M4VC57
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184267:A11Q RS07350
gene id: 1184267:A11Q_RS07350
uniprot id: M4VB29
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1184267:A11Q RS04860
gene id: 1184267:A11Q_RS04860
uniprot id: M4VPW7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1184267:A11Q RS04820
gene id: 1184267:A11Q_RS04820
uniprot id: M4VAX6
names: Similarity
messages: Belongs to the PrpD family.

1184267:A11Q RS12220
gene id: 1184267:A11Q_RS12220
uniprot id: M4VF19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1184267:A11Q RS07490
gene id: 1184267:A11Q_RS07490
uniprot id: M4V912
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1184267:A11Q RS06190
gene id: 1184267:A11Q_RS06190
uniprot id: M4V8B0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1184267:A11Q RS06615
gene id: 1184267:A11Q_RS06615
uniprot id: M4VBY8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1184267:A11Q RS03490
gene id: 1184267:A11Q_RS03490
uniprot id: M4VA66
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1184267:A11Q RS10255
gene id: 1184267:A11Q_RS10255
uniprot id: M4VDY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS07280
gene id: 1184267:A11Q_RS07280
uniprot id: M4VB14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1184267:A11Q RS09615
gene id: 1184267:A11Q_RS09615
uniprot id: M4VA86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1184267:A11Q RS00995
gene id: 1184267:A11Q_RS00995
uniprot id: M4V7K8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1184267:A11Q RS09155
gene id: 1184267:A11Q_RS09155
uniprot id: M4VDD7
names: Similarity
messages: Belongs to the LOG family.

1184267:A11Q RS11425
gene id: 1184267:A11Q_RS11425
uniprot id: M4VEP2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1184267:A11Q RS11225
gene id: 1184267:A11Q_RS11225
uniprot id: M4VAL7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS08845
gene id: 1184267:A11Q_RS08845
uniprot id: M4VD82
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1184267:A11Q RS08445
gene id: 1184267:A11Q_RS08445
uniprot id: M4VRT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1184267:A11Q RS11150
gene id: 1184267:A11Q_RS11150
uniprot id: M4VAJ8
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1184267:A11Q RS03695
gene id: 1184267:A11Q_RS03695
uniprot id: M4V6F6
names: Similarity
messages: Belongs to the sigma-54 factor family.

1184267:A11Q RS01490
gene id: 1184267:A11Q_RS01490
uniprot id: M4VN69
names: Similarity
messages: Belongs to the Gfa family.

1184267:A11Q RS05440
gene id: 1184267:A11Q_RS05440
uniprot id: M4VB97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1184267:A11Q RS03500
gene id: 1184267:A11Q_RS03500
uniprot id: M4V6U1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1184267:A11Q RS05845
gene id: 1184267:A11Q_RS05845
uniprot id: M4VA85
names: Similarity
messages: Belongs to the MipA/OmpV family.

1184267:A11Q RS07420
gene id: 1184267:A11Q_RS07420
uniprot id: M4VR89
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1184267:A11Q RS02555
gene id: 1184267:A11Q_RS02555
uniprot id: M4V5U4
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS10455
gene id: 1184267:A11Q_RS10455
uniprot id: M4VE23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1184267:A11Q RS09175
gene id: 1184267:A11Q_RS09175
uniprot id: M4VC45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1184267:A11Q RS06800
gene id: 1184267:A11Q_RS06800
uniprot id: M4V8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1184267:A11Q RS07720
gene id: 1184267:A11Q_RS07720
uniprot id: M4VB95
names: Similarity
messages: Belongs to the YicC/YloC family.

1184267:A11Q RS03035
gene id: 1184267:A11Q_RS03035
uniprot id: M4VNX2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1184267:A11Q RS13150
gene id: 1184267:A11Q_RS13150
uniprot id: M4VUE0
names: Similarity
messages: Belongs to the ParB family.

1184267:A11Q RS03075
gene id: 1184267:A11Q_RS03075
uniprot id: M4V642
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1184267:A11Q RS02395
gene id: 1184267:A11Q_RS02395
uniprot id: M4V9J6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1184267:A11Q RS03740
gene id: 1184267:A11Q_RS03740
uniprot id: M4VAD1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1184267:A11Q RS03770
gene id: 1184267:A11Q_RS03770
uniprot id: M4V6J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1184267:A11Q RS11365
gene id: 1184267:A11Q_RS11365
uniprot id: M4VTG7
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1184267:A11Q RS08720
gene id: 1184267:A11Q_RS08720
uniprot id: M4VD40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1184267:A11Q RS06635
gene id: 1184267:A11Q_RS06635
uniprot id: M4VAP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1184267:A11Q RS03565
gene id: 1184267:A11Q_RS03565
uniprot id: M4VA81
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1184267:A11Q RS03050
gene id: 1184267:A11Q_RS03050
uniprot id: M4V638
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1184267:A11Q RS09230
gene id: 1184267:A11Q_RS09230
uniprot id: M4VDE9
names: Similarity
messages: Belongs to the TOP6A family.

1184267:A11Q RS10590
gene id: 1184267:A11Q_RS10590
uniprot id: M4VA83
names: Similarity
messages: Belongs to the LEA type 2 family.

1184267:A11Q RS05420
gene id: 1184267:A11Q_RS05420
uniprot id: M4V7C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1184267:A11Q RS12875
gene id: 1184267:A11Q_RS12875
uniprot id: M4VC07
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1184267:A11Q RS10185
gene id: 1184267:A11Q_RS10185
uniprot id: M4VA05
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS08160
gene id: 1184267:A11Q_RS08160
uniprot id: M4VCS5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1184267:A11Q RS01315
gene id: 1184267:A11Q_RS01315
uniprot id: M4VN43
names: Similarity
messages: Belongs to the YjdM family.

1184267:A11Q RS03755
gene id: 1184267:A11Q_RS03755
uniprot id: M4VPC2
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1184267:A11Q RS11710
gene id: 1184267:A11Q_RS11710
uniprot id: M4VBG2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1184267:A11Q RS02240
gene id: 1184267:A11Q_RS02240
uniprot id: M4VNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1184267:A11Q RS00845
gene id: 1184267:A11Q_RS00845
uniprot id: M4V8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS13260
gene id: 1184267:A11Q_RS13260
uniprot id: M4VN58
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS13570
gene id: 1184267:A11Q_RS13570
uniprot id: M4V9M7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1184267:A11Q RS13165
gene id: 1184267:A11Q_RS13165
uniprot id: M4VBQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1184267:A11Q RS02880
gene id: 1184267:A11Q_RS02880
uniprot id: M4V6G5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1184267:A11Q RS10810
gene id: 1184267:A11Q_RS10810
uniprot id: M4VAC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1184267:A11Q RS05435
gene id: 1184267:A11Q_RS05435
uniprot id: M4VA09
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1184267:A11Q RS09830
gene id: 1184267:A11Q_RS09830
uniprot id: M4VDP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1184267:A11Q RS11705
gene id: 1184267:A11Q_RS11705
uniprot id: M4VAY8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1184267:A11Q RS03020
gene id: 1184267:A11Q_RS03020
uniprot id: M4V9W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1184267:A11Q RS06460
gene id: 1184267:A11Q_RS06460
uniprot id: M4VBW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1184267:A11Q RS04780
gene id: 1184267:A11Q_RS04780
uniprot id: M4V7I4
names: Similarity
messages: Belongs to the peptidase M1 family.

1184267:A11Q RS03175
gene id: 1184267:A11Q_RS03175
uniprot id: M4VA01
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS11440
gene id: 1184267:A11Q_RS11440
uniprot id: M4VTI0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1184267:A11Q RS11590
gene id: 1184267:A11Q_RS11590
uniprot id: M4VTK6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1184267:A11Q RS02845
gene id: 1184267:A11Q_RS02845
uniprot id: M4V9T5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1184267:A11Q RS06840
gene id: 1184267:A11Q_RS06840
uniprot id: M4VC27
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1184267:A11Q RS02495
gene id: 1184267:A11Q_RS02495
uniprot id: M4V9L7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1184267:A11Q RS09385
gene id: 1184267:A11Q_RS09385
uniprot id: M4V9L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1184267:A11Q RS09170
gene id: 1184267:A11Q_RS09170
uniprot id: M4VS76
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1184267:A11Q RS08130
gene id: 1184267:A11Q_RS08130
uniprot id: M4VBH4
names: Similarity
messages: Belongs to the BolA/IbaG family.

1184267:A11Q RS01695
gene id: 1184267:A11Q_RS01695
uniprot id: M4V7Z8
names: Subcellular Location Annotation
messages: Cytoplasm

1184267:A11Q RS03285
gene id: 1184267:A11Q_RS03285
uniprot id: M4V678
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1184267:A11Q RS06500
gene id: 1184267:A11Q_RS06500
uniprot id: M4VQT8
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS10985
gene id: 1184267:A11Q_RS10985
uniprot id: M4VB03
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1184267:A11Q RS13120
gene id: 1184267:A11Q_RS13120
uniprot id: M4VC58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1184267:A11Q RS07930
gene id: 1184267:A11Q_RS07930
uniprot id: M4VCN0
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS05135
gene id: 1184267:A11Q_RS05135
uniprot id: M4V9V5
names: Similarity
messages: Belongs to the peptidase C1 family.

1184267:A11Q RS02625
gene id: 1184267:A11Q_RS02625
uniprot id: M4V9P2
names: Subcellular Location Annotation
messages: Cytoplasm

1184267:A11Q RS02680
gene id: 1184267:A11Q_RS02680
uniprot id: M4V5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1184267:A11Q RS08490
gene id: 1184267:A11Q_RS08490
uniprot id: M4V921
names: Similarity
messages: Belongs to the glutamine synthetase family.

1184267:A11Q RS08540
gene id: 1184267:A11Q_RS08540
uniprot id: M4V933
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1184267:A11Q RS00295
gene id: 1184267:A11Q_RS00295
uniprot id: M4V765
names: Similarity
messages: Belongs to the DapB family.

1184267:A11Q RS00010
gene id: 1184267:A11Q_RS00010
uniprot id: M4V4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1184267:A11Q RS02370
gene id: 1184267:A11Q_RS02370
uniprot id: M4V9J1
names: Similarity
messages: Belongs to the EPSP synthase family.

1184267:A11Q RS13185
gene id: 1184267:A11Q_RS13185
uniprot id: M4VFK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1184267:A11Q RS03875
gene id: 1184267:A11Q_RS03875
uniprot id: M4V6K9
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS01575
gene id: 1184267:A11Q_RS01575
uniprot id: M4V953
names: Similarity
messages: Belongs to the pirin family.

1184267:A11Q RS09970
gene id: 1184267:A11Q_RS09970
uniprot id: M4VSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1184267:A11Q RS02250
gene id: 1184267:A11Q_RS02250
uniprot id: M4V9G7
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09725
gene id: 1184267:A11Q_RS09725
uniprot id: M4VCD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS10105
gene id: 1184267:A11Q_RS10105
uniprot id: M4VDV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1184267:A11Q RS12325
gene id: 1184267:A11Q_RS12325
uniprot id: M4VB92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184267:A11Q RS06305
gene id: 1184267:A11Q_RS06305
uniprot id: M4VBU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1184267:A11Q RS09740
gene id: 1184267:A11Q_RS09740
uniprot id: M4VAA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1184267:A11Q RS04220
gene id: 1184267:A11Q_RS04220
uniprot id: M4VAL8
names: Similarity
messages: Belongs to the peptidase S49 family.

1184267:A11Q RS04420
gene id: 1184267:A11Q_RS04420
uniprot id: M4VAQ3
names: Similarity
messages: Belongs to the peptidase S1C family.

1184267:A11Q RS11250
gene id: 1184267:A11Q_RS11250
uniprot id: M4VEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS00735
gene id: 1184267:A11Q_RS00735
uniprot id: M4V7F8
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1184267:A11Q RS10160
gene id: 1184267:A11Q_RS10160
uniprot id: M4VA00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1184267:A11Q RS12865
gene id: 1184267:A11Q_RS12865
uniprot id: M4VFE1
names: Similarity
messages: Belongs to the GSP E family.

1184267:A11Q RS12960
gene id: 1184267:A11Q_RS12960
uniprot id: M4VFG3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1184267:A11Q RS09060
gene id: 1184267:A11Q_RS09060
uniprot id: M4V9F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1184267:A11Q RS12880
gene id: 1184267:A11Q_RS12880
uniprot id: M4VU83
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1184267:A11Q RS12835
gene id: 1184267:A11Q_RS12835
uniprot id: M4VE43
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS04120
gene id: 1184267:A11Q_RS04120
uniprot id: M4VAJ9
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS10710
gene id: 1184267:A11Q_RS10710
uniprot id: M4VAA8
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS11230
gene id: 1184267:A11Q_RS11230
uniprot id: M4VB58
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1184267:A11Q RS08205
gene id: 1184267:A11Q_RS08205
uniprot id: M4VCT6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1184267:A11Q RS00415
gene id: 1184267:A11Q_RS00415
uniprot id: M4VMJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1184267:A11Q RS02075
gene id: 1184267:A11Q_RS02075
uniprot id: M4V5K8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1184267:A11Q RS07535
gene id: 1184267:A11Q_RS07535
uniprot id: M4V922
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1184267:A11Q RS04950
gene id: 1184267:A11Q_RS04950
uniprot id: M4V732
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1184267:A11Q RS12020
gene id: 1184267:A11Q_RS12020
uniprot id: M4VDP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1184267:A11Q RS02780
gene id: 1184267:A11Q_RS02780
uniprot id: M4V6F0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1184267:A11Q RS09595
gene id: 1184267:A11Q_RS09595
uniprot id: M4VSF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1184267:A11Q RS03290
gene id: 1184267:A11Q_RS03290
uniprot id: M4V6P6
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS10690
gene id: 1184267:A11Q_RS10690
uniprot id: M4VAT1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1184267:A11Q RS09645
gene id: 1184267:A11Q_RS09645
uniprot id: M4VSF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1184267:A11Q RS05735
gene id: 1184267:A11Q_RS05735
uniprot id: M4V811
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1184267:A11Q RS09585
gene id: 1184267:A11Q_RS09585
uniprot id: M4V9Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1184267:A11Q RS00570
gene id: 1184267:A11Q_RS00570
uniprot id: M4V8J7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1184267:A11Q RS02860
gene id: 1184267:A11Q_RS02860
uniprot id: M4VNU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1184267:A11Q RS02080
gene id: 1184267:A11Q_RS02080
uniprot id: M4V626
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1184267:A11Q RS01340
gene id: 1184267:A11Q_RS01340
uniprot id: M4VN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1184267:A11Q RS09445
gene id: 1184267:A11Q_RS09445
uniprot id: M4VSC3
names: Similarity
messages: Belongs to the peptidase M13 family.

1184267:A11Q RS05170
gene id: 1184267:A11Q_RS05170
uniprot id: M4V774
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1184267:A11Q RS09625
gene id: 1184267:A11Q_RS09625
uniprot id: M4VCC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1184267:A11Q RS04510
gene id: 1184267:A11Q_RS04510
uniprot id: M4VPQ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1184267:A11Q RS04810
gene id: 1184267:A11Q_RS04810
uniprot id: M4VPV9
names: Similarity
messages: Belongs to the citrate synthase family.

1184267:A11Q RS09650
gene id: 1184267:A11Q_RS09650
uniprot id: M4VCC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1184267:A11Q RS06740
gene id: 1184267:A11Q_RS06740
uniprot id: M4VC10
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1184267:A11Q RS11700
gene id: 1184267:A11Q_RS11700
uniprot id: M4VET5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1184267:A11Q RS05415
gene id: 1184267:A11Q_RS05415
uniprot id: M4VB93
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1184267:A11Q RS09225
gene id: 1184267:A11Q_RS09225
uniprot id: M4VC52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1184267:A11Q RS03680
gene id: 1184267:A11Q_RS03680
uniprot id: M4VP93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1184267:A11Q RS08930
gene id: 1184267:A11Q_RS08930
uniprot id: M4V9D8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1184267:A11Q RS07355
gene id: 1184267:A11Q_RS07355
uniprot id: M4VCC0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1184267:A11Q RS04025
gene id: 1184267:A11Q_RS04025
uniprot id: M4V6N1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1184267:A11Q RS11940
gene id: 1184267:A11Q_RS11940
uniprot id: M4VTR1
names: Similarity
messages: Belongs to the GSP E family.

1184267:A11Q RS03625
gene id: 1184267:A11Q_RS03625
uniprot id: M4V6W8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1184267:A11Q RS06760
gene id: 1184267:A11Q_RS06760
uniprot id: M4VAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1184267:A11Q RS03900
gene id: 1184267:A11Q_RS03900
uniprot id: M4V6L2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1184267:A11Q RS07760
gene id: 1184267:A11Q_RS07760
uniprot id: M4V961
names: Similarity
messages: Belongs to the peptidase M16 family.

1184267:A11Q RS01590
gene id: 1184267:A11Q_RS01590
uniprot id: M4VN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1184267:A11Q RS10140
gene id: 1184267:A11Q_RS10140
uniprot id: M4VAH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1184267:A11Q RS06295
gene id: 1184267:A11Q_RS06295
uniprot id: M4VQP9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1184267:A11Q RS05500
gene id: 1184267:A11Q_RS05500
uniprot id: M4V7W0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS02455
gene id: 1184267:A11Q_RS02455
uniprot id: M4V690
names: Similarity
messages: Belongs to the DEAD box helicase family.

1184267:A11Q RS07410
gene id: 1184267:A11Q_RS07410
uniprot id: M4V8G8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1184267:A11Q RS07750
gene id: 1184267:A11Q_RS07750
uniprot id: M4VCJ8
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09630
gene id: 1184267:A11Q_RS09630
uniprot id: M4VDL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1184267:A11Q RS06795
gene id: 1184267:A11Q_RS06795
uniprot id: M4V855
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

1184267:A11Q RS07755
gene id: 1184267:A11Q_RS07755
uniprot id: M4V8N3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1184267:A11Q RS09560
gene id: 1184267:A11Q_RS09560
uniprot id: M4V9P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1184267:A11Q RS04405
gene id: 1184267:A11Q_RS04405
uniprot id: M4V7B5
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS10250
gene id: 1184267:A11Q_RS10250
uniprot id: M4VCN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1184267:A11Q RS08225
gene id: 1184267:A11Q_RS08225
uniprot id: M4VBJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1184267:A11Q RS06530
gene id: 1184267:A11Q_RS06530
uniprot id: M4VQU1
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1184267:A11Q RS05675
gene id: 1184267:A11Q_RS05675
uniprot id: M4V7H5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1184267:A11Q RS02605
gene id: 1184267:A11Q_RS02605
uniprot id: M4V5V4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1184267:A11Q RS00355
gene id: 1184267:A11Q_RS00355
uniprot id: M4V4N0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1184267:A11Q RS02870
gene id: 1184267:A11Q_RS02870
uniprot id: M4V9U0
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS11385
gene id: 1184267:A11Q_RS11385
uniprot id: M4VBB0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1184267:A11Q RS00150
gene id: 1184267:A11Q_RS00150
uniprot id: M4V737
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1184267:A11Q RS09055
gene id: 1184267:A11Q_RS09055
uniprot id: M4VDC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1184267:A11Q RS07660
gene id: 1184267:A11Q_RS07660
uniprot id: M4V945
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1184267:A11Q RS13355
gene id: 1184267:A11Q_RS13355
uniprot id: M4V645
names: Similarity
messages: Belongs to the bacterial secretin family.

1184267:A11Q RS10400
gene id: 1184267:A11Q_RS10400
uniprot id: M4VCR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1184267:A11Q RS12740
gene id: 1184267:A11Q_RS12740
uniprot id: M4VFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1184267:A11Q RS12930
gene id: 1184267:A11Q_RS12930
uniprot id: M4VU95
names: Similarity
messages: Belongs to the GSP E family.

1184267:A11Q RS08240
gene id: 1184267:A11Q_RS08240
uniprot id: M4V9F8
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS02640
gene id: 1184267:A11Q_RS02640
uniprot id: M4VNQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1184267:A11Q RS04275
gene id: 1184267:A11Q_RS04275
uniprot id: M4V795
names: Caution
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1184267:A11Q RS07705
gene id: 1184267:A11Q_RS07705
uniprot id: M4V8M4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1184267:A11Q RS08325
gene id: 1184267:A11Q_RS08325
uniprot id: M4VBL5
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS08780
gene id: 1184267:A11Q_RS08780
uniprot id: M4V9T7
names: Similarity
messages: Belongs to the ArsC family.

1184267:A11Q RS11900
gene id: 1184267:A11Q_RS11900
uniprot id: M4VEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1184267:A11Q RS04840
gene id: 1184267:A11Q_RS04840
uniprot id: M4V9Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1184267:A11Q RS05145
gene id: 1184267:A11Q_RS05145
uniprot id: M4V768
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1184267:A11Q RS02730
gene id: 1184267:A11Q_RS02730
uniprot id: M4V5X8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1184267:A11Q RS00925
gene id: 1184267:A11Q_RS00925
uniprot id: M4V8R4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1184267:A11Q RS08465
gene id: 1184267:A11Q_RS08465
uniprot id: M4V916
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1184267:A11Q RS12480
gene id: 1184267:A11Q_RS12480
uniprot id: M4VBT4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1184267:A11Q RS13115
gene id: 1184267:A11Q_RS13115
uniprot id: M4VBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1184267:A11Q RS05635
gene id: 1184267:A11Q_RS05635
uniprot id: M4VQA6
names: Similarity
messages: Belongs to the RutC family.

1184267:A11Q RS02580
gene id: 1184267:A11Q_RS02580
uniprot id: M4V5V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1184267:A11Q RS07125
gene id: 1184267:A11Q_RS07125
uniprot id: M4VC76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1184267:A11Q RS02885
gene id: 1184267:A11Q_RS02885
uniprot id: M4VNU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1184267:A11Q RS05715
gene id: 1184267:A11Q_RS05715
uniprot id: M4VQC0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1184267:A11Q RS11935
gene id: 1184267:A11Q_RS11935
uniprot id: M4VBK1
names: Similarity
messages: Belongs to the bacterial secretin family.

1184267:A11Q RS12980
gene id: 1184267:A11Q_RS12980
uniprot id: M4VE74
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1184267:A11Q RS09505
gene id: 1184267:A11Q_RS09505
uniprot id: M4VDJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1184267:A11Q RS05185
gene id: 1184267:A11Q_RS05185
uniprot id: M4V9W4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS00025
gene id: 1184267:A11Q_RS00025
uniprot id: M4V716
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1184267:A11Q RS06300
gene id: 1184267:A11Q_RS06300
uniprot id: M4VAJ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1184267:A11Q RS00340
gene id: 1184267:A11Q_RS00340
uniprot id: M4VMH6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1184267:A11Q RS02360
gene id: 1184267:A11Q_RS02360
uniprot id: M4VNL2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1184267:A11Q RS09270
gene id: 1184267:A11Q_RS09270
uniprot id: M4VS92
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1184267:A11Q RS02315
gene id: 1184267:A11Q_RS02315
uniprot id: M4V8A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1184267:A11Q RS04185
gene id: 1184267:A11Q_RS04185
uniprot id: M4VPK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1184267:A11Q RS03000
gene id: 1184267:A11Q_RS03000
uniprot id: M4V629
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1184267:A11Q RS01375
gene id: 1184267:A11Q_RS01375
uniprot id: M4V920
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS13390
gene id: 1184267:A11Q_RS13390
uniprot id: M4VPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1184267:A11Q RS07485
gene id: 1184267:A11Q_RS07485
uniprot id: M4V8I4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1184267:A11Q RS01350
gene id: 1184267:A11Q_RS01350
uniprot id: M4V915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS02955
gene id: 1184267:A11Q_RS02955
uniprot id: M4V6H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1184267:A11Q RS13060
gene id: 1184267:A11Q_RS13060
uniprot id: M4VFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1184267:A11Q RS09065
gene id: 1184267:A11Q_RS09065
uniprot id: M4V9Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1184267:A11Q RS08090
gene id: 1184267:A11Q_RS08090
uniprot id: M4V8U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1184267:A11Q RS04590
gene id: 1184267:A11Q_RS04590
uniprot id: M4V9L0
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS05285
gene id: 1184267:A11Q_RS05285
uniprot id: M4VQ45
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS02850
gene id: 1184267:A11Q_RS02850
uniprot id: M4V601
names: Similarity
messages: Belongs to the bacterial flagellin family.

1184267:A11Q RS09575
gene id: 1184267:A11Q_RS09575
uniprot id: M4VCB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1184267:A11Q RS00240
gene id: 1184267:A11Q_RS00240
uniprot id: M4VMF9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1184267:A11Q RS09570
gene id: 1184267:A11Q_RS09570
uniprot id: M4VSE5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1184267:A11Q RS03155
gene id: 1184267:A11Q_RS03155
uniprot id: M4V654
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS10085
gene id: 1184267:A11Q_RS10085
uniprot id: M4V9Y6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1184267:A11Q RS03010
gene id: 1184267:A11Q_RS03010
uniprot id: M4VNW8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1184267:A11Q RS00885
gene id: 1184267:A11Q_RS00885
uniprot id: M4V5D5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1184267:A11Q RS12215
gene id: 1184267:A11Q_RS12215
uniprot id: M4VDS4
names: Similarity
messages: Belongs to the peptidase S58 family.

1184267:A11Q RS07115
gene id: 1184267:A11Q_RS07115
uniprot id: M4VR36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1184267:A11Q RS02280
gene id: 1184267:A11Q_RS02280
uniprot id: M4V5P1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1184267:A11Q RS11290
gene id: 1184267:A11Q_RS11290
uniprot id: M4VTC7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1184267:A11Q RS03700
gene id: 1184267:A11Q_RS03700
uniprot id: M4V6Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS04205
gene id: 1184267:A11Q_RS04205
uniprot id: M4V782
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1184267:A11Q RS05965
gene id: 1184267:A11Q_RS05965
uniprot id: M4V7M6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

1184267:A11Q RS09070
gene id: 1184267:A11Q_RS09070
uniprot id: M4VS60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1184267:A11Q RS04655
gene id: 1184267:A11Q_RS04655
uniprot id: M4V7G1
names: Similarity
messages: Belongs to the ribF family.

1184267:A11Q RS10485
gene id: 1184267:A11Q_RS10485
uniprot id: M4VA64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1184267:A11Q RS10180
gene id: 1184267:A11Q_RS10180
uniprot id: M4VDX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1184267:A11Q RS05840
gene id: 1184267:A11Q_RS05840
uniprot id: M4VQE6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1184267:A11Q RS13090
gene id: 1184267:A11Q_RS13090
uniprot id: M4VBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1184267:A11Q RS05365
gene id: 1184267:A11Q_RS05365
uniprot id: M4VB83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

1184267:A11Q RS09820
gene id: 1184267:A11Q_RS09820
uniprot id: M4VSI1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1184267:A11Q RS05975
gene id: 1184267:A11Q_RS05975
uniprot id: M4VQG9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS09555
gene id: 1184267:A11Q_RS09555
uniprot id: M4VDK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1184267:A11Q RS07005
gene id: 1184267:A11Q_RS07005
uniprot id: M4V898
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1184267:A11Q RS04985
gene id: 1184267:A11Q_RS04985
uniprot id: M4VPY9
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1184267:A11Q RS11405
gene id: 1184267:A11Q_RS11405
uniprot id: M4VAT5
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS03025
gene id: 1184267:A11Q_RS03025
uniprot id: M4V633
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1184267:A11Q RS13170
gene id: 1184267:A11Q_RS13170
uniprot id: M4VC66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1184267:A11Q RS10700
gene id: 1184267:A11Q_RS10700
uniprot id: M4VCX5
names: Similarity
messages: Belongs to the leucine-binding protein family.

1184267:A11Q RS10150
gene id: 1184267:A11Q_RS10150
uniprot id: M4VCL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS04155
gene id: 1184267:A11Q_RS04155
uniprot id: M4V773
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1184267:A11Q RS05195
gene id: 1184267:A11Q_RS05195
uniprot id: M4V779
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1184267:A11Q RS03750
gene id: 1184267:A11Q_RS03750
uniprot id: M4V709
names: Similarity
messages: Belongs to the CarB family.

1184267:A11Q RS10500
gene id: 1184267:A11Q_RS10500
uniprot id: M4VCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1184267:A11Q RS12645
gene id: 1184267:A11Q_RS12645
uniprot id: M4VBF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1184267:A11Q RS07710
gene id: 1184267:A11Q_RS07710
uniprot id: M4V954
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1184267:A11Q RS04715
gene id: 1184267:A11Q_RS04715
uniprot id: M4V9N4
names: Similarity
messages: Belongs to the peptidase C15 family.

1184267:A11Q RS10845
gene id: 1184267:A11Q_RS10845
uniprot id: M4VT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1184267:A11Q RS00020
gene id: 1184267:A11Q_RS00020
uniprot id: M4VMB9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1184267:A11Q RS06315
gene id: 1184267:A11Q_RS06315
uniprot id: M4V8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1184267:A11Q RS06940
gene id: 1184267:A11Q_RS06940
uniprot id: M4V884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1184267:A11Q RS07340
gene id: 1184267:A11Q_RS07340
uniprot id: M4V8Y3
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09665
gene id: 1184267:A11Q_RS09665
uniprot id: M4VA94
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1184267:A11Q RS11520
gene id: 1184267:A11Q_RS11520
uniprot id: M4VDG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1184267:A11Q RS06730
gene id: 1184267:A11Q_RS06730
uniprot id: M4VQX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS11745
gene id: 1184267:A11Q_RS11745
uniprot id: M4VDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1184267:A11Q RS01295
gene id: 1184267:A11Q_RS01295
uniprot id: M4V7T6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1184267:A11Q RS10965
gene id: 1184267:A11Q_RS10965
uniprot id: M4VT58
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS04915
gene id: 1184267:A11Q_RS04915
uniprot id: M4V9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1184267:A11Q RS04300
gene id: 1184267:A11Q_RS04300
uniprot id: M4V799
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1184267:A11Q RS07790
gene id: 1184267:A11Q_RS07790
uniprot id: M4VRG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1184267:A11Q RS13130
gene id: 1184267:A11Q_RS13130
uniprot id: M4VEA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1184267:A11Q RS01005
gene id: 1184267:A11Q_RS01005
uniprot id: M4V508
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1184267:A11Q RS00665
gene id: 1184267:A11Q_RS00665
uniprot id: M4V7E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1184267:A11Q RS11125
gene id: 1184267:A11Q_RS11125
uniprot id: M4VEG6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1184267:A11Q RS06405
gene id: 1184267:A11Q_RS06405
uniprot id: M4VAL5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1184267:A11Q RS12640
gene id: 1184267:A11Q_RS12640
uniprot id: M4VF97
names: Caution
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS08535
gene id: 1184267:A11Q_RS08535
uniprot id: M4VD03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS07975
gene id: 1184267:A11Q_RS07975
uniprot id: M4VBE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1184267:A11Q RS07455
gene id: 1184267:A11Q_RS07455
uniprot id: M4VCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1184267:A11Q RS09605
gene id: 1184267:A11Q_RS09605
uniprot id: M4VDL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1184267:A11Q RS11970
gene id: 1184267:A11Q_RS11970
uniprot id: M4VDN3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS07120
gene id: 1184267:A11Q_RS07120
uniprot id: M4VAY5
names: Similarity
messages: Belongs to the RecJ family.

1184267:A11Q RS08560
gene id: 1184267:A11Q_RS08560
uniprot id: M4VD09
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS13200
gene id: 1184267:A11Q_RS13200
uniprot id: M4V8C3
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS05985
gene id: 1184267:A11Q_RS05985
uniprot id: M4VBK4
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS07635
gene id: 1184267:A11Q_RS07635
uniprot id: M4V941
names: Similarity
messages: Belongs to the GSP E family.

1184267:A11Q RS08060
gene id: 1184267:A11Q_RS08060
uniprot id: M4V8T8
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1184267:A11Q RS06475
gene id: 1184267:A11Q_RS06475
uniprot id: M4VQT4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1184267:A11Q RS11065
gene id: 1184267:A11Q_RS11065
uniprot id: M4VT77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1184267:A11Q RS10520
gene id: 1184267:A11Q_RS10520
uniprot id: M4VAP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1184267:A11Q RS01485
gene id: 1184267:A11Q_RS01485
uniprot id: M4V5S5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1184267:A11Q RS06655
gene id: 1184267:A11Q_RS06655
uniprot id: M4VQW1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1184267:A11Q RS07590
gene id: 1184267:A11Q_RS07590
uniprot id: M4VRC2
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS10820
gene id: 1184267:A11Q_RS10820
uniprot id: M4VT29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1184267:A11Q RS03715
gene id: 1184267:A11Q_RS03715
uniprot id: M4VAB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1184267:A11Q RS13195
gene id: 1184267:A11Q_RS13195
uniprot id: M4VC72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1184267:A11Q RS06880
gene id: 1184267:A11Q_RS06880
uniprot id: M4VAT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1184267:A11Q RS04190
gene id: 1184267:A11Q_RS04190
uniprot id: M4V9D2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1184267:A11Q RS02340
gene id: 1184267:A11Q_RS02340
uniprot id: M4V8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184267:A11Q RS09075
gene id: 1184267:A11Q_RS09075
uniprot id: M4VC29
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1184267:A11Q RS05260
gene id: 1184267:A11Q_RS05260
uniprot id: M4VQ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1184267:A11Q RS00405
gene id: 1184267:A11Q_RS00405
uniprot id: M4V4P0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1184267:A11Q RS10670
gene id: 1184267:A11Q_RS10670
uniprot id: M4VSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1184267:A11Q RS07325
gene id: 1184267:A11Q_RS07325
uniprot id: M4VB24
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1184267:A11Q RS04850
gene id: 1184267:A11Q_RS04850
uniprot id: M4V715
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1184267:A11Q RS10885
gene id: 1184267:A11Q_RS10885
uniprot id: M4VAE2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS01975
gene id: 1184267:A11Q_RS01975
uniprot id: M4V5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1184267:A11Q RS06670
gene id: 1184267:A11Q_RS06670
uniprot id: M4V834
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS02630
gene id: 1184267:A11Q_RS02630
uniprot id: M4V5V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1184267:A11Q RS09640
gene id: 1184267:A11Q_RS09640
uniprot id: M4VA90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1184267:A11Q RS07980
gene id: 1184267:A11Q_RS07980
uniprot id: M4VCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1184267:A11Q RS04230
gene id: 1184267:A11Q_RS04230
uniprot id: M4V787
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09485
gene id: 1184267:A11Q_RS09485
uniprot id: M4V9N1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1184267:A11Q RS11500
gene id: 1184267:A11Q_RS11500
uniprot id: M4VEQ3
names: Similarity
messages: Belongs to the nitroreductase family.

1184267:A11Q RS02810
gene id: 1184267:A11Q_RS02810
uniprot id: M4VNT6
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1184267:A11Q RS07070
gene id: 1184267:A11Q_RS07070
uniprot id: M4VAX7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1184267:A11Q RS08145
gene id: 1184267:A11Q_RS08145
uniprot id: M4V9D6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1184267:A11Q RS04710
gene id: 1184267:A11Q_RS04710
uniprot id: M4VPU3
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1184267:A11Q RS08115
gene id: 1184267:A11Q_RS08115
uniprot id: M4V8U9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1184267:A11Q RS13520
gene id: 1184267:A11Q_RS13520
uniprot id: M4VQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1184267:A11Q RS09460
gene id: 1184267:A11Q_RS09460
uniprot id: M4V9M8
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS00790
gene id: 1184267:A11Q_RS00790
uniprot id: M4V8P0
names: Similarity
messages: Belongs to the GST superfamily.

1184267:A11Q RS11945
gene id: 1184267:A11Q_RS11945
uniprot id: M4VDN0
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS05280
gene id: 1184267:A11Q_RS05280
uniprot id: M4V7S0
names: Similarity
messages: Belongs to the peptidase M13 family.

1184267:A11Q RS06310
gene id: 1184267:A11Q_RS06310
uniprot id: M4V7X0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1184267:A11Q RS04020
gene id: 1184267:A11Q_RS04020
uniprot id: M4VAI6
names: Similarity
messages: In the C-terminal section; belongs to the DHPS family.

1184267:A11Q RS00350
gene id: 1184267:A11Q_RS00350
uniprot id: M4V8F7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1184267:A11Q RS03385
gene id: 1184267:A11Q_RS03385
uniprot id: M4V8W9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1184267:A11Q RS10595
gene id: 1184267:A11Q_RS10595
uniprot id: M4VAR0
names: Similarity
messages: Belongs to the citrate synthase family.

1184267:A11Q RS05390
gene id: 1184267:A11Q_RS05390
uniprot id: M4VB89
names: Similarity
messages: Belongs to the arginase family.

1184267:A11Q RS09020
gene id: 1184267:A11Q_RS09020
uniprot id: M4VC20
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS04295
gene id: 1184267:A11Q_RS04295
uniprot id: M4V6S9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS08655
gene id: 1184267:A11Q_RS08655
uniprot id: M4V9P9
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS06395
gene id: 1184267:A11Q_RS06395
uniprot id: M4V8H4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1184267:A11Q RS05530
gene id: 1184267:A11Q_RS05530
uniprot id: M4VQ88
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1184267:A11Q RS06150
gene id: 1184267:A11Q_RS06150
uniprot id: M4VQK3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1184267:A11Q RS10610
gene id: 1184267:A11Q_RS10610
uniprot id: M4VE50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1184267:A11Q RS08565
gene id: 1184267:A11Q_RS08565
uniprot id: M4V939
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1184267:A11Q RS08360
gene id: 1184267:A11Q_RS08360
uniprot id: M4V8Z6
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS00655
gene id: 1184267:A11Q_RS00655
uniprot id: M4V590
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1184267:A11Q RS08255
gene id: 1184267:A11Q_RS08255
uniprot id: M4VCU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1184267:A11Q RS04815
gene id: 1184267:A11Q_RS04815
uniprot id: M4V9Q1
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1184267:A11Q RS03850
gene id: 1184267:A11Q_RS03850
uniprot id: M4V6K5
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS02585
gene id: 1184267:A11Q_RS02585
uniprot id: M4V6B4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1184267:A11Q RS09400
gene id: 1184267:A11Q_RS09400
uniprot id: M4VC81
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS00835
gene id: 1184267:A11Q_RS00835
uniprot id: M4VMS6
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS04665
gene id: 1184267:A11Q_RS04665
uniprot id: M4V9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1184267:A11Q RS05620
gene id: 1184267:A11Q_RS05620
uniprot id: M4VBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1184267:A11Q RS10565
gene id: 1184267:A11Q_RS10565
uniprot id: M4VA78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1184267:A11Q RS10750
gene id: 1184267:A11Q_RS10750
uniprot id: M4VCY6
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS02255
gene id: 1184267:A11Q_RS02255
uniprot id: M4V5N6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1184267:A11Q RS04930
gene id: 1184267:A11Q_RS04930
uniprot id: M4V7K9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1184267:A11Q RS07920
gene id: 1184267:A11Q_RS07920
uniprot id: M4VRI5
names: Similarity
messages: Belongs to the CapA family.

1184267:A11Q RS09150
gene id: 1184267:A11Q_RS09150
uniprot id: M4VC41
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS01260
gene id: 1184267:A11Q_RS01260
uniprot id: M4V580
names: Similarity
messages: Belongs to the SCO1/2 family.

1184267:A11Q RS02590
gene id: 1184267:A11Q_RS02590
uniprot id: M4VNQ0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1184267:A11Q RS08420
gene id: 1184267:A11Q_RS08420
uniprot id: M4VRS9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1184267:A11Q RS11020
gene id: 1184267:A11Q_RS11020
uniprot id: M4VD42
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS06770
gene id: 1184267:A11Q_RS06770
uniprot id: M4V850
names: Similarity
messages: Belongs to the SufE family.

1184267:A11Q RS13125
gene id: 1184267:A11Q_RS13125
uniprot id: M4VUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1184267:A11Q RS08480
gene id: 1184267:A11Q_RS08480
uniprot id: M4VBP3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1184267:A11Q RS09550
gene id: 1184267:A11Q_RS09550
uniprot id: M4VCA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1184267:A11Q RS12465
gene id: 1184267:A11Q_RS12465
uniprot id: M4VDX1
names: Similarity
messages: Belongs to the peptidase C56 family.

1184267:A11Q RS06815
gene id: 1184267:A11Q_RS06815
uniprot id: M4VC22
names: Similarity
messages: Belongs to the peptidase S66 family.

1184267:A11Q RS10815
gene id: 1184267:A11Q_RS10815
uniprot id: M4VAW2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1184267:A11Q RS04910
gene id: 1184267:A11Q_RS04910
uniprot id: M4VPX5
names: Similarity
messages: Belongs to the thioredoxin family.

1184267:A11Q RS11865
gene id: 1184267:A11Q_RS11865
uniprot id: M4VTP8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1184267:A11Q RS07275
gene id: 1184267:A11Q_RS07275
uniprot id: M4VR64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1184267:A11Q RS05665
gene id: 1184267:A11Q_RS05665
uniprot id: M4VA54
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1184267:A11Q RS13080
gene id: 1184267:A11Q_RS13080
uniprot id: M4VE96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1184267:A11Q RS08375
gene id: 1184267:A11Q_RS08375
uniprot id: M4VBM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1184267:A11Q RS04620
gene id: 1184267:A11Q_RS04620
uniprot id: M4VAT6
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1184267:A11Q RS06640
gene id: 1184267:A11Q_RS06640
uniprot id: M4VBZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1184267:A11Q RS10935
gene id: 1184267:A11Q_RS10935
uniprot id: M4VAF3
names: Similarity
messages: Belongs to the arginase family.

1184267:A11Q RS02615
gene id: 1184267:A11Q_RS02615
uniprot id: M4VNQ4
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS06280
gene id: 1184267:A11Q_RS06280
uniprot id: M4VBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1184267:A11Q RS03725
gene id: 1184267:A11Q_RS03725
uniprot id: M4V6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1184267:A11Q RS03990
gene id: 1184267:A11Q_RS03990
uniprot id: M4V9A1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS10890
gene id: 1184267:A11Q_RS10890
uniprot id: M4VAX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS09235
gene id: 1184267:A11Q_RS09235
uniprot id: M4V9I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1184267:A11Q RS07785
gene id: 1184267:A11Q_RS07785
uniprot id: M4V964
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1184267:A11Q RS05165
gene id: 1184267:A11Q_RS05165
uniprot id: M4VB48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1184267:A11Q RS12435
gene id: 1184267:A11Q_RS12435
uniprot id: M4VTZ3
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1184267:A11Q RS08190
gene id: 1184267:A11Q_RS08190
uniprot id: M4V9E8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS10410
gene id: 1184267:A11Q_RS10410
uniprot id: M4VA52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1184267:A11Q RS10660
gene id: 1184267:A11Q_RS10660
uniprot id: M4VA97
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1184267:A11Q RS03985
gene id: 1184267:A11Q_RS03985
uniprot id: M4VPF9
names: Similarity
messages: Belongs to the peptidase S41A family.

1184267:A11Q RS02380
gene id: 1184267:A11Q_RS02380
uniprot id: M4V675
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1184267:A11Q RS07730
gene id: 1184267:A11Q_RS07730
uniprot id: M4V8M9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1184267:A11Q RS02490
gene id: 1184267:A11Q_RS02490
uniprot id: M4V8D8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1184267:A11Q RS11575
gene id: 1184267:A11Q_RS11575
uniprot id: M4VER4
names: Similarity
messages: Belongs to the peptidase M24B family.

1184267:A11Q RS00055
gene id: 1184267:A11Q_RS00055
uniprot id: M4V8A6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1184267:A11Q RS02705
gene id: 1184267:A11Q_RS02705
uniprot id: M4V5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1184267:A11Q RS03375
gene id: 1184267:A11Q_RS03375
uniprot id: M4V6R2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1184267:A11Q RS03510
gene id: 1184267:A11Q_RS03510
uniprot id: M4V8Z3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1184267:A11Q RS02260
gene id: 1184267:A11Q_RS02260
uniprot id: M4V655
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1184267:A11Q RS03090
gene id: 1184267:A11Q_RS03090
uniprot id: M4V8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS06265
gene id: 1184267:A11Q_RS06265
uniprot id: M4V8D2
names: Similarity
messages: Belongs to the aspartokinase family.

1184267:A11Q RS09515
gene id: 1184267:A11Q_RS09515
uniprot id: M4VA70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1184267:A11Q RS09190
gene id: 1184267:A11Q_RS09190
uniprot id: M4VA19
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1184267:A11Q RS05820
gene id: 1184267:A11Q_RS05820
uniprot id: M4VA80
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09750
gene id: 1184267:A11Q_RS09750
uniprot id: M4VCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1184267:A11Q RS09125
gene id: 1184267:A11Q_RS09125
uniprot id: M4VC37
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1184267:A11Q RS09920
gene id: 1184267:A11Q_RS09920
uniprot id: M4VSJ5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1184267:A11Q RS06390
gene id: 1184267:A11Q_RS06390
uniprot id: M4V7Y5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1184267:A11Q RS04055
gene id: 1184267:A11Q_RS04055
uniprot id: M4V756
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1184267:A11Q RS05790
gene id: 1184267:A11Q_RS05790
uniprot id: M4VQD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184267:A11Q RS00440
gene id: 1184267:A11Q_RS00440
uniprot id: M4VMJ7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS12745
gene id: 1184267:A11Q_RS12745
uniprot id: M4VBH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1184267:A11Q RS07780
gene id: 1184267:A11Q_RS07780
uniprot id: M4V8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1184267:A11Q RS11400
gene id: 1184267:A11Q_RS11400
uniprot id: M4VEN8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1184267:A11Q RS12375
gene id: 1184267:A11Q_RS12375
uniprot id: M4VBA1
names: Similarity
messages: Belongs to the ArsC family.

1184267:A11Q RS10240
gene id: 1184267:A11Q_RS10240
uniprot id: M4VAI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1184267:A11Q RS00160
gene id: 1184267:A11Q_RS00160
uniprot id: M4V4J4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1184267:A11Q RS08915
gene id: 1184267:A11Q_RS08915
uniprot id: M4VS33
names: Similarity
messages: Belongs to the GPI family.

1184267:A11Q RS04855
gene id: 1184267:A11Q_RS04855
uniprot id: M4V7J7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1184267:A11Q RS00620
gene id: 1184267:A11Q_RS00620
uniprot id: M4V8K8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1184267:A11Q RS13070
gene id: 1184267:A11Q_RS13070
uniprot id: M4VC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

1184267:A11Q RS12355
gene id: 1184267:A11Q_RS12355
uniprot id: M4VBR5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1184267:A11Q RS07405
gene id: 1184267:A11Q_RS07405
uniprot id: M4VCD0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1184267:A11Q RS05010
gene id: 1184267:A11Q_RS05010
uniprot id: M4VPZ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1184267:A11Q RS00300
gene id: 1184267:A11Q_RS00300
uniprot id: M4V8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1184267:A11Q RS01710
gene id: 1184267:A11Q_RS01710
uniprot id: M4V5W3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1184267:A11Q RS07330
gene id: 1184267:A11Q_RS07330
uniprot id: M4VCB5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1184267:A11Q RS00710
gene id: 1184267:A11Q_RS00710
uniprot id: M4V7F3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1184267:A11Q RS11540
gene id: 1184267:A11Q_RS11540
uniprot id: M4VTJ7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1184267:A11Q RS09955
gene id: 1184267:A11Q_RS09955
uniprot id: M4VDS5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1184267:A11Q RS13220
gene id: 1184267:A11Q_RS13220
uniprot id: M4V7D2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1184267:A11Q RS01305
gene id: 1184267:A11Q_RS01305
uniprot id: M4V587
names: Similarity
messages: Belongs to the pirin family.

1184267:A11Q RS03065
gene id: 1184267:A11Q_RS03065
uniprot id: M4V8P7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184267:A11Q RS08020
gene id: 1184267:A11Q_RS08020
uniprot id: M4VRK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

1184267:A11Q RS05495
gene id: 1184267:A11Q_RS05495
uniprot id: M4V7D9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1184267:A11Q RS03975
gene id: 1184267:A11Q_RS03975
uniprot id: M4V6M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1184267:A11Q RS06910
gene id: 1184267:A11Q_RS06910
uniprot id: M4VC40
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1184267:A11Q RS00590
gene id: 1184267:A11Q_RS00590
uniprot id: M4V7C7
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS04180
gene id: 1184267:A11Q_RS04180
uniprot id: M4V777
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1184267:A11Q RS07050
gene id: 1184267:A11Q_RS07050
uniprot id: M4VC63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1184267:A11Q RS00945
gene id: 1184267:A11Q_RS00945
uniprot id: M4V7K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1184267:A11Q RS13450
gene id: 1184267:A11Q_RS13450
uniprot id: M4VA26
names: Similarity
messages: Belongs to the DEAD box helicase family.

1184267:A11Q RS06570
gene id: 1184267:A11Q_RS06570
uniprot id: M4V816
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS09760
gene id: 1184267:A11Q_RS09760
uniprot id: M4V9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1184267:A11Q RS00320
gene id: 1184267:A11Q_RS00320
uniprot id: M4V770
names: Subcellular Location Annotation
messages: Cytoplasm

1184267:A11Q RS10285
gene id: 1184267:A11Q_RS10285
uniprot id: M4VA27
names: Similarity
messages: Belongs to the peptidase S13 family.

1184267:A11Q RS02155
gene id: 1184267:A11Q_RS02155
uniprot id: M4V5L9
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS13440
gene id: 1184267:A11Q_RS13440
uniprot id: M4VQ65
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1184267:A11Q RS13320
gene id: 1184267:A11Q_RS13320
uniprot id: M4V9K6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1184267:A11Q RS13110
gene id: 1184267:A11Q_RS13110
uniprot id: M4VFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1184267:A11Q RS12945
gene id: 1184267:A11Q_RS12945
uniprot id: M4VC23
names: Similarity
messages: Belongs to the peptidase M16 family.

1184267:A11Q RS04625
gene id: 1184267:A11Q_RS04625
uniprot id: M4V6Y3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1184267:A11Q RS11600
gene id: 1184267:A11Q_RS11600
uniprot id: M4VER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1184267:A11Q RS09030
gene id: 1184267:A11Q_RS09030
uniprot id: M4V9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1184267:A11Q RS02720
gene id: 1184267:A11Q_RS02720
uniprot id: M4V8H5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS04035
gene id: 1184267:A11Q_RS04035
uniprot id: M4VPG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS05350
gene id: 1184267:A11Q_RS05350
uniprot id: M4V7A9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1184267:A11Q RS07530
gene id: 1184267:A11Q_RS07530
uniprot id: M4V8J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

1184267:A11Q RS07770
gene id: 1184267:A11Q_RS07770
uniprot id: M4VBA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1184267:A11Q RS03795
gene id: 1184267:A11Q_RS03795
uniprot id: M4V6J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1184267:A11Q RS11395
gene id: 1184267:A11Q_RS11395
uniprot id: M4VDD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS04340
gene id: 1184267:A11Q_RS04340
uniprot id: M4VAP2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1184267:A11Q RS09590
gene id: 1184267:A11Q_RS09590
uniprot id: M4VA82
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1184267:A11Q RS10775
gene id: 1184267:A11Q_RS10775
uniprot id: M4VCZ0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1184267:A11Q RS05360
gene id: 1184267:A11Q_RS05360
uniprot id: M4V9Z6
names: Similarity
messages: Belongs to the SELO family.

1184267:A11Q RS08750
gene id: 1184267:A11Q_RS08750
uniprot id: M4V978
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1184267:A11Q RS01650
gene id: 1184267:A11Q_RS01650
uniprot id: M4V963
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1184267:A11Q RS06535
gene id: 1184267:A11Q_RS06535
uniprot id: M4VAN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1184267:A11Q RS04210
gene id: 1184267:A11Q_RS04210
uniprot id: M4VPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1184267:A11Q RS09565
gene id: 1184267:A11Q_RS09565
uniprot id: M4VA77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1184267:A11Q RS09160
gene id: 1184267:A11Q_RS09160
uniprot id: M4V9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1184267:A11Q RS08790
gene id: 1184267:A11Q_RS08790
uniprot id: M4VBW4
names: Similarity
messages: Belongs to the UPRTase family.

1184267:A11Q RS03095
gene id: 1184267:A11Q_RS03095
uniprot id: M4V9Y4
names: Similarity
messages: Belongs to the GSP E family.

1184267:A11Q RS09610
gene id: 1184267:A11Q_RS09610
uniprot id: M4V9Q6
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1184267:A11Q RS09735
gene id: 1184267:A11Q_RS09735
uniprot id: M4V9S5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184267:A11Q RS06820
gene id: 1184267:A11Q_RS06820
uniprot id: M4V861
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1184267:A11Q RS00670
gene id: 1184267:A11Q_RS00670
uniprot id: M4V8L7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1184267:A11Q RS10290
gene id: 1184267:A11Q_RS10290
uniprot id: M4VAK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1184267:A11Q RS08510
gene id: 1184267:A11Q_RS08510
uniprot id: M4VCZ8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1184267:A11Q RS06090
gene id: 1184267:A11Q_RS06090
uniprot id: M4V7Q2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1184267:A11Q RS10065
gene id: 1184267:A11Q_RS10065
uniprot id: M4VAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1184267:A11Q RS07575
gene id: 1184267:A11Q_RS07575
uniprot id: M4VCG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1184267:A11Q RS00760
gene id: 1184267:A11Q_RS00760
uniprot id: M4V7G3
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09720
gene id: 1184267:A11Q_RS09720
uniprot id: M4VSG6
names: Function
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

1184267:A11Q RS13420
gene id: 1184267:A11Q_RS13420
uniprot id: M4VAW0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1184267:A11Q RS08590
gene id: 1184267:A11Q_RS08590
uniprot id: M4V943
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1184267:A11Q RS04160
gene id: 1184267:A11Q_RS04160
uniprot id: M4VPJ7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1184267:A11Q RS10135
gene id: 1184267:A11Q_RS10135
uniprot id: M4V9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1184267:A11Q RS04830
gene id: 1184267:A11Q_RS04830
uniprot id: M4V7J2
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09495
gene id: 1184267:A11Q_RS09495
uniprot id: M4VSD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1184267:A11Q RS11980
gene id: 1184267:A11Q_RS11980
uniprot id: M4VB36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1184267:A11Q RS10120
gene id: 1184267:A11Q_RS10120
uniprot id: M4VSN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1184267:A11Q RS09950
gene id: 1184267:A11Q_RS09950
uniprot id: M4VCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1184267:A11Q RS05200
gene id: 1184267:A11Q_RS05200
uniprot id: M4V7Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1184267:A11Q RS04400
gene id: 1184267:A11Q_RS04400
uniprot id: M4V6U6
names: Similarity
messages: Belongs to the UPF0234 family.

1184267:A11Q RS07460
gene id: 1184267:A11Q_RS07460
uniprot id: M4V8H8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1184267:A11Q RS05290
gene id: 1184267:A11Q_RS05290
uniprot id: M4V9Y2
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS03950
gene id: 1184267:A11Q_RS03950
uniprot id: M4V6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1184267:A11Q RS01640
gene id: 1184267:A11Q_RS01640
uniprot id: M4VN94
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1184267:A11Q RS09525
gene id: 1184267:A11Q_RS09525
uniprot id: M4VCA3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1184267:A11Q RS04730
gene id: 1184267:A11Q_RS04730
uniprot id: M4V7H6
names: Similarity
messages: Belongs to the peptidase M17 family.

1184267:A11Q RS09660
gene id: 1184267:A11Q_RS09660
uniprot id: M4V9R6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1184267:A11Q RS03330
gene id: 1184267:A11Q_RS03330
uniprot id: M4VP27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1184267:A11Q RS04870
gene id: 1184267:A11Q_RS04870
uniprot id: M4VAY4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1184267:A11Q RS10320
gene id: 1184267:A11Q_RS10320
uniprot id: M4VSS9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1184267:A11Q RS10425
gene id: 1184267:A11Q_RS10425
uniprot id: M4VCS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

1184267:A11Q RS09025
gene id: 1184267:A11Q_RS09025
uniprot id: M4VDB8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS01290
gene id: 1184267:A11Q_RS01290
uniprot id: M4VN40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1184267:A11Q RS01535
gene id: 1184267:A11Q_RS01535
uniprot id: M4V5T4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1184267:A11Q RS10095
gene id: 1184267:A11Q_RS10095
uniprot id: M4VSN0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1184267:A11Q RS03310
gene id: 1184267:A11Q_RS03310
uniprot id: M4V8V5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1184267:A11Q RS12735
gene id: 1184267:A11Q_RS12735
uniprot id: M4VE26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1184267:A11Q RS02710
gene id: 1184267:A11Q_RS02710
uniprot id: M4V6D4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS00285
gene id: 1184267:A11Q_RS00285
uniprot id: M4V518
names: Similarity
messages: Belongs to the diaminopimelate epimerase family.

1184267:A11Q RS00105
gene id: 1184267:A11Q_RS00105
uniprot id: M4V8B8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1184267:A11Q RS03765
gene id: 1184267:A11Q_RS03765
uniprot id: M4VAE6
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS07865
gene id: 1184267:A11Q_RS07865
uniprot id: M4V980
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1184267:A11Q RS12655
gene id: 1184267:A11Q_RS12655
uniprot id: M4VU35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1184267:A11Q RS09135
gene id: 1184267:A11Q_RS09135
uniprot id: M4V9H0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1184267:A11Q RS06180
gene id: 1184267:A11Q_RS06180
uniprot id: M4VBP5
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1184267:A11Q RS03590
gene id: 1184267:A11Q_RS03590
uniprot id: M4VA87
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1184267:A11Q RS07685
gene id: 1184267:A11Q_RS07685
uniprot id: M4V949
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS03620
gene id: 1184267:A11Q_RS03620
uniprot id: M4V6E1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS12910
gene id: 1184267:A11Q_RS12910
uniprot id: M4VE58
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09260
gene id: 1184267:A11Q_RS09260
uniprot id: M4V9J4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1184267:A11Q RS04940
gene id: 1184267:A11Q_RS04940
uniprot id: M4V9S3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1184267:A11Q RS00015
gene id: 1184267:A11Q_RS00015
uniprot id: M4V4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1184267:A11Q RS06950
gene id: 1184267:A11Q_RS06950
uniprot id: M4VAV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1184267:A11Q RS08210
gene id: 1184267:A11Q_RS08210
uniprot id: M4V8X0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1184267:A11Q RS06900
gene id: 1184267:A11Q_RS06900
uniprot id: M4VQZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS09635
gene id: 1184267:A11Q_RS09635
uniprot id: M4V9R1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1184267:A11Q RS04895
gene id: 1184267:A11Q_RS04895
uniprot id: M4VAZ0
names: Similarity
messages: Belongs to the DprA/Smf family.

1184267:A11Q RS01495
gene id: 1184267:A11Q_RS01495
uniprot id: M4V7W7
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1184267:A11Q RS03670
gene id: 1184267:A11Q_RS03670
uniprot id: M4V6F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1184267:A11Q RS09815
gene id: 1184267:A11Q_RS09815
uniprot id: M4VAB7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1184267:A11Q RS12750
gene id: 1184267:A11Q_RS12750
uniprot id: M4VBX9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1184267:A11Q RS10825
gene id: 1184267:A11Q_RS10825
uniprot id: M4VD02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1184267:A11Q RS12850
gene id: 1184267:A11Q_RS12850
uniprot id: M4VC01
names: Similarity
messages: Belongs to the UPF0145 family.

1184267:A11Q RS13140
gene id: 1184267:A11Q_RS13140
uniprot id: M4VBP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1184267:A11Q RS09545
gene id: 1184267:A11Q_RS09545
uniprot id: M4VSE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1184267:A11Q RS11640
gene id: 1184267:A11Q_RS11640
uniprot id: M4VTL3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1184267:A11Q RS00540
gene id: 1184267:A11Q_RS00540
uniprot id: M4V7B7
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS02535
gene id: 1184267:A11Q_RS02535
uniprot id: M4VNP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1184267:A11Q RS01280
gene id: 1184267:A11Q_RS01280
uniprot id: M4V901
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1184267:A11Q RS10115
gene id: 1184267:A11Q_RS10115
uniprot id: M4VAG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1184267:A11Q RS02825
gene id: 1184267:A11Q_RS02825
uniprot id: M4V5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1184267:A11Q RS10100
gene id: 1184267:A11Q_RS10100
uniprot id: M4VCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1184267:A11Q RS09680
gene id: 1184267:A11Q_RS09680
uniprot id: M4VCD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1184267:A11Q RS00690
gene id: 1184267:A11Q_RS00690
uniprot id: M4V7E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1184267:A11Q RS01120
gene id: 1184267:A11Q_RS01120
uniprot id: M4V7M9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1184267:A11Q RS01630
gene id: 1184267:A11Q_RS01630
uniprot id: M4V5E0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1184267:A11Q RS02410
gene id: 1184267:A11Q_RS02410
uniprot id: M4VNM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1184267:A11Q RS05100
gene id: 1184267:A11Q_RS05100
uniprot id: M4V7N9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1184267:A11Q RS02330
gene id: 1184267:A11Q_RS02330
uniprot id: M4V666
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1184267:A11Q RS07640
gene id: 1184267:A11Q_RS07640
uniprot id: M4VRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1184267:A11Q RS06850
gene id: 1184267:A11Q_RS06850
uniprot id: M4V8P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1184267:A11Q RS04775
gene id: 1184267:A11Q_RS04775
uniprot id: M4V705
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1184267:A11Q RS08920
gene id: 1184267:A11Q_RS08920
uniprot id: M4VBZ9
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1184267:A11Q RS10090
gene id: 1184267:A11Q_RS10090
uniprot id: M4VAG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS09670
gene id: 1184267:A11Q_RS09670
uniprot id: M4VSG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS10875
gene id: 1184267:A11Q_RS10875
uniprot id: M4VD12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1184267:A11Q RS06705
gene id: 1184267:A11Q_RS06705
uniprot id: M4VQW7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1184267:A11Q RS07890
gene id: 1184267:A11Q_RS07890
uniprot id: M4V985
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1184267:A11Q RS07605
gene id: 1184267:A11Q_RS07605
uniprot id: M4V8K4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1184267:A11Q RS07415
gene id: 1184267:A11Q_RS07415
uniprot id: M4V8Z5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1184267:A11Q RS06400
gene id: 1184267:A11Q_RS06400
uniprot id: M4VQS0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1184267:A11Q RS04900
gene id: 1184267:A11Q_RS04900
uniprot id: M4V722
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1184267:A11Q RS08410
gene id: 1184267:A11Q_RS08410
uniprot id: M4V907
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1184267:A11Q RS11595
gene id: 1184267:A11Q_RS11595
uniprot id: M4VDH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1184267:A11Q RS01900
gene id: 1184267:A11Q_RS01900
uniprot id: M4V5Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1184267:A11Q RS02550
gene id: 1184267:A11Q_RS02550
uniprot id: M4V9M6
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS06210
gene id: 1184267:A11Q_RS06210
uniprot id: M4V7S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184267:A11Q RS03555
gene id: 1184267:A11Q_RS03555
uniprot id: M4VP70
names: Similarity
messages: Belongs to the GSP E family.

1184267:A11Q RS09450
gene id: 1184267:A11Q_RS09450
uniprot id: M4VC89
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1184267:A11Q RS07555
gene id: 1184267:A11Q_RS07555
uniprot id: M4V8J5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1184267:A11Q RS03630
gene id: 1184267:A11Q_RS03630
uniprot id: M4VP84
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1184267:A11Q RS11880
gene id: 1184267:A11Q_RS11880
uniprot id: M4VB18
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1184267:A11Q RS08625
gene id: 1184267:A11Q_RS08625
uniprot id: M4V947
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1184267:A11Q RS09455
gene id: 1184267:A11Q_RS09455
uniprot id: M4VDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1184267:A11Q RS00600
gene id: 1184267:A11Q_RS00600
uniprot id: M4V4S7
names: Similarity
messages: Belongs to the pirin family.

1184267:A11Q RS13385
gene id: 1184267:A11Q_RS13385
uniprot id: M4V6W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1184267:A11Q RS07290
gene id: 1184267:A11Q_RS07290
uniprot id: M4V8E6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1184267:A11Q RS09835
gene id: 1184267:A11Q_RS09835
uniprot id: M4V9U3
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS05595
gene id: 1184267:A11Q_RS05595
uniprot id: M4V7G0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1184267:A11Q RS12650
gene id: 1184267:A11Q_RS12650
uniprot id: M4VBW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1184267:A11Q RS03895
gene id: 1184267:A11Q_RS03895
uniprot id: M4VAG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1184267:A11Q RS10805
gene id: 1184267:A11Q_RS10805
uniprot id: M4VE94
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1184267:A11Q RS00345
gene id: 1184267:A11Q_RS00345
uniprot id: M4V776
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1184267:A11Q RS02685
gene id: 1184267:A11Q_RS02685
uniprot id: M4V6D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1184267:A11Q RS00265
gene id: 1184267:A11Q_RS00265
uniprot id: M4VMG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1184267:A11Q RS00085
gene id: 1184267:A11Q_RS00085
uniprot id: M4V4H9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1184267:A11Q RS10170
gene id: 1184267:A11Q_RS10170
uniprot id: M4VSP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1184267:A11Q RS07475
gene id: 1184267:A11Q_RS07475
uniprot id: M4VB52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1184267:A11Q RS09220
gene id: 1184267:A11Q_RS09220
uniprot id: M4VS86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1184267:A11Q RS08230
gene id: 1184267:A11Q_RS08230
uniprot id: M4VCT9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1184267:A11Q RS12720
gene id: 1184267:A11Q_RS12720
uniprot id: M4VBG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1184267:A11Q RS02300
gene id: 1184267:A11Q_RS02300
uniprot id: M4V9H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1184267:A11Q RS10490
gene id: 1184267:A11Q_RS10490
uniprot id: M4VAP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1184267:A11Q RS07230
gene id: 1184267:A11Q_RS07230
uniprot id: M4VC95
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1184267:A11Q RS07105
gene id: 1184267:A11Q_RS07105
uniprot id: M4V8B6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184267:A11Q RS10865
gene id: 1184267:A11Q_RS10865
uniprot id: M4VAX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1184267:A11Q RS06545
gene id: 1184267:A11Q_RS06545
uniprot id: M4V813
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1184267:A11Q RS04325
gene id: 1184267:A11Q_RS04325
uniprot id: M4V7A3
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS09050
gene id: 1184267:A11Q_RS09050
uniprot id: M4VC25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1184267:A11Q RS00090
gene id: 1184267:A11Q_RS00090
uniprot id: M4V4Y2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1184267:A11Q RS10405
gene id: 1184267:A11Q_RS10405
uniprot id: M4VE13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1184267:A11Q RS01180
gene id: 1184267:A11Q_RS01180
uniprot id: M4V544
names: Similarity
messages: Belongs to the catalase family.

1184267:A11Q RS09805
gene id: 1184267:A11Q_RS09805
uniprot id: M4VDP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1184267:A11Q RS09655
gene id: 1184267:A11Q_RS09655
uniprot id: M4VDM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1184267:A11Q RS07715
gene id: 1184267:A11Q_RS07715
uniprot id: M4VRE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1184267:A11Q RS10765
gene id: 1184267:A11Q_RS10765
uniprot id: M4VAV1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1184267:A11Q RS05720
gene id: 1184267:A11Q_RS05720
uniprot id: M4VA63
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1184267:A11Q RS11205
gene id: 1184267:A11Q_RS11205
uniprot id: M4VB51
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1184267:A11Q RS08235
gene id: 1184267:A11Q_RS08235
uniprot id: M4V8X6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1184267:A11Q RS04480
gene id: 1184267:A11Q_RS04480
uniprot id: M4V7D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1184267:A11Q RS10640
gene id: 1184267:A11Q_RS10640
uniprot id: M4VA93
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1184267:A11Q RS02485
gene id: 1184267:A11Q_RS02485
uniprot id: M4VNN4
names: Similarity
messages: Belongs to the Nth/MutY family.

1184267:A11Q RS05155
gene id: 1184267:A11Q_RS05155
uniprot id: M4VQ21
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS05080
gene id: 1184267:A11Q_RS05080
uniprot id: M4V7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS09530
gene id: 1184267:A11Q_RS09530
uniprot id: M4VDK3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1184267:A11Q RS01155
gene id: 1184267:A11Q_RS01155
uniprot id: M4V541
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS12955
gene id: 1184267:A11Q_RS12955
uniprot id: M4VE68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1184267:A11Q RS03275
gene id: 1184267:A11Q_RS03275
uniprot id: M4V8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1184267:A11Q RS09535
gene id: 1184267:A11Q_RS09535
uniprot id: M4V9P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1184267:A11Q RS08170
gene id: 1184267:A11Q_RS08170
uniprot id: M4V9E0
names: Subcellular Location Annotation
messages: Nucleus

1184267:A11Q RS08710
gene id: 1184267:A11Q_RS08710
uniprot id: M4VRZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS07085
gene id: 1184267:A11Q_RS07085
uniprot id: M4V8T7
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS04580
gene id: 1184267:A11Q_RS04580
uniprot id: M4V7E7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

1184267:A11Q RS07795
gene id: 1184267:A11Q_RS07795
uniprot id: M4VBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1184267:A11Q RS09985
gene id: 1184267:A11Q_RS09985
uniprot id: M4V9W8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1184267:A11Q RS11760
gene id: 1184267:A11Q_RS11760
uniprot id: M4VBH1
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1184267:A11Q RS07725
gene id: 1184267:A11Q_RS07725
uniprot id: M4VCJ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1184267:A11Q RS07525
gene id: 1184267:A11Q_RS07525
uniprot id: M4VCF5
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1184267:A11Q RS07630
gene id: 1184267:A11Q_RS07630
uniprot id: M4V8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

1184267:A11Q RS12050
gene id: 1184267:A11Q_RS12050
uniprot id: M4VEZ5
names: Similarity
messages: Belongs to the glutamate synthase family.

1184267:A11Q RS07075
gene id: 1184267:A11Q_RS07075
uniprot id: M4VC68
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1184267:A11Q RS09620
gene id: 1184267:A11Q_RS09620
uniprot id: M4VSF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1184267:A11Q RS02620
gene id: 1184267:A11Q_RS02620
uniprot id: M4V8F6
names: Similarity
messages: Belongs to the UPF0235 family.

1184267:A11Q RS02165
gene id: 1184267:A11Q_RS02165
uniprot id: M4VNH6
names: Similarity
messages: Belongs to the peptidase S8 family.

1184267:A11Q RS09510
gene id: 1184267:A11Q_RS09510
uniprot id: M4V9N6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1184267:A11Q RS10345
gene id: 1184267:A11Q_RS10345
uniprot id: M4VST4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates ribosomal protein L11.

1184267:A11Q RS11555
gene id: 1184267:A11Q_RS11555
uniprot id: M4VAW1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1184267:A11Q RS10790
gene id: 1184267:A11Q_RS10790
uniprot id: M4VAV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1184267:A11Q RS02795
gene id: 1184267:A11Q_RS02795
uniprot id: M4V9S6
names: Similarity
messages: Belongs to the aspartokinase family.

1184267:A11Q RS07130
gene id: 1184267:A11Q_RS07130
uniprot id: M4V8C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1184267:A11Q RS09580
gene id: 1184267:A11Q_RS09580
uniprot id: M4VDL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1184267:A11Q RS03435
gene id: 1184267:A11Q_RS03435
uniprot id: M4V8X8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1184267:A11Q RS04255
gene id: 1184267:A11Q_RS04255
uniprot id: M4VPL6
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1184267:A11Q RS06995
gene id: 1184267:A11Q_RS06995
uniprot id: M4VAW3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1184267:A11Q RS04495
gene id: 1184267:A11Q_RS04495
uniprot id: M4VAR4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1184267:A11Q RS12005
gene id: 1184267:A11Q_RS12005
uniprot id: M4VB41
names: Similarity
messages: Belongs to the pirin family.

1184267:A11Q RS00960
gene id: 1184267:A11Q_RS00960
uniprot id: M4V5F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1184267:A11Q RS01015
gene id: 1184267:A11Q_RS01015
uniprot id: M4VMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1184267:A11Q RS07390
gene id: 1184267:A11Q_RS07390
uniprot id: M4V8Z1
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS03530
gene id: 1184267:A11Q_RS03530
uniprot id: M4VP66
names: Similarity
messages: Belongs to the SfsA family.

1184267:A11Q RS07480
gene id: 1184267:A11Q_RS07480
uniprot id: M4VCE5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1184267:A11Q RS01615
gene id: 1184267:A11Q_RS01615
uniprot id: M4VN89
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1184267:A11Q RS06270
gene id: 1184267:A11Q_RS06270
uniprot id: M4VQN8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1184267:A11Q RS08985
gene id: 1184267:A11Q_RS08985
uniprot id: M4V9Y5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1184267:A11Q RS06645
gene id: 1184267:A11Q_RS06645
uniprot id: M4V830
names: Similarity
messages: Belongs to the fabD family.

1184267:A11Q RS00410
gene id: 1184267:A11Q_RS00410
uniprot id: M4V542
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1184267:A11Q RS00005
gene id: 1184267:A11Q_RS00005
uniprot id: M4V897
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1184267:A11Q RS10685
gene id: 1184267:A11Q_RS10685
uniprot id: M4VAA2
names: Subcellular Location Annotation
messages: Membrane

1184267:A11Q RS05655
gene id: 1184267:A11Q_RS05655
uniprot id: M4V7Z3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1184267:A11Q RS03615
gene id: 1184267:A11Q_RS03615
uniprot id: M4VA92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1184267:A11Q RS05995
gene id: 1184267:A11Q_RS05995
uniprot id: M4V867
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1184267:A11Q RS03180
gene id: 1184267:A11Q_RS03180
uniprot id: M4V660
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1184267:A11Q RS03060
gene id: 1184267:A11Q_RS03060
uniprot id: M4VNX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1184267:A11Q RS12900
gene id: 1184267:A11Q_RS12900
uniprot id: M4VC12
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.