1182568:SU48 RS03660
gene id: 1182568:SU48_RS03660
uniprot id: A0A172T7K8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1182568:SU48 RS06835
gene id: 1182568:SU48_RS06835
uniprot id: A0A172T9P8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1182568:SU48 RS09515
gene id: 1182568:SU48_RS09515
uniprot id: A0A172TAB9
names: Similarity
messages: Belongs to the PGI/PMI family.

1182568:SU48 RS00270
gene id: 1182568:SU48_RS00270
uniprot id: A0A172T672
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1182568:SU48 RS02350
gene id: 1182568:SU48_RS02350
uniprot id: A0A172T794
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1182568:SU48 RS10475
gene id: 1182568:SU48_RS10475
uniprot id: A0A172TAS4
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS08775
gene id: 1182568:SU48_RS08775
uniprot id: A0A172TA21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1182568:SU48 RS07530
gene id: 1182568:SU48_RS07530
uniprot id: A0A172TDH9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1182568:SU48 RS09835
gene id: 1182568:SU48_RS09835
uniprot id: A0A172TAH9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1182568:SU48 RS02400
gene id: 1182568:SU48_RS02400
uniprot id: A0A172T779
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1182568:SU48 RS00460
gene id: 1182568:SU48_RS00460
uniprot id: A0A172T621
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS07590
gene id: 1182568:SU48_RS07590
uniprot id: A0A172T9P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1182568:SU48 RS05390
gene id: 1182568:SU48_RS05390
uniprot id: A0A172T8M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS02700
gene id: 1182568:SU48_RS02700
uniprot id: A0A172T7P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1182568:SU48 RS03095
gene id: 1182568:SU48_RS03095
uniprot id: A0A172T7G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1182568:SU48 RS02485
gene id: 1182568:SU48_RS02485
uniprot id: A0A172T7B4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1182568:SU48 RS05830
gene id: 1182568:SU48_RS05830
uniprot id: A0A172TCM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS10450
gene id: 1182568:SU48_RS10450
uniprot id: A0A172TB05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1182568:SU48 RS11320
gene id: 1182568:SU48_RS11320
uniprot id: A0A172TBF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1182568:SU48 RS06195
gene id: 1182568:SU48_RS06195
uniprot id: A0A172T8S0
names: Subcellular Location Annotation
messages: Cytoplasm

1182568:SU48 RS02440
gene id: 1182568:SU48_RS02440
uniprot id: A0A172T745
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1182568:SU48 RS09880
gene id: 1182568:SU48_RS09880
uniprot id: A0A172TD17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1182568:SU48 RS11525
gene id: 1182568:SU48_RS11525
uniprot id: A0A172TBW6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1182568:SU48 RS02430
gene id: 1182568:SU48_RS02430
uniprot id: A0A172T6Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1182568:SU48 RS03760
gene id: 1182568:SU48_RS03760
uniprot id: A0A172T895
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1182568:SU48 RS04180
gene id: 1182568:SU48_RS04180
uniprot id: A0A172T7X8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1182568:SU48 RS13465
gene id: 1182568:SU48_RS13465
uniprot id: A0A172TC84
names: Similarity
messages: Belongs to the RutC family.

1182568:SU48 RS11310
gene id: 1182568:SU48_RS11310
uniprot id: A0A172TB23
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1182568:SU48 RS05925
gene id: 1182568:SU48_RS05925
uniprot id: A0A172T8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1182568:SU48 RS02395
gene id: 1182568:SU48_RS02395
uniprot id: A0A172T7K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1182568:SU48 RS06675
gene id: 1182568:SU48_RS06675
uniprot id: A0A172T900
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1182568:SU48 RS00835
gene id: 1182568:SU48_RS00835
uniprot id: A0A172T6G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS00590
gene id: 1182568:SU48_RS00590
uniprot id: A0A172T6D6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1182568:SU48 RS11385
gene id: 1182568:SU48_RS11385
uniprot id: A0A172TB76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1182568:SU48 RS08525
gene id: 1182568:SU48_RS08525
uniprot id: A0A172TD47
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1182568:SU48 RS09530
gene id: 1182568:SU48_RS09530
uniprot id: A0A172TAD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS04215
gene id: 1182568:SU48_RS04215
uniprot id: A0A172T831
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1182568:SU48 RS12780
gene id: 1182568:SU48_RS12780
uniprot id: A0A172TBX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1182568:SU48 RS09420
gene id: 1182568:SU48_RS09420
uniprot id: A0A172TAX5
names: Similarity
messages: Belongs to the lycopene cyclase family.

1182568:SU48 RS00350
gene id: 1182568:SU48_RS00350
uniprot id: A0A172T694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1182568:SU48 RS10575
gene id: 1182568:SU48_RS10575
uniprot id: A0A172TAT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1182568:SU48 RS01250
gene id: 1182568:SU48_RS01250
uniprot id: A0A172T6M2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1182568:SU48 RS13090
gene id: 1182568:SU48_RS13090
uniprot id: A0A172TC54
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1182568:SU48 RS06145
gene id: 1182568:SU48_RS06145
uniprot id: A0A172T8Q8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1182568:SU48 RS11760
gene id: 1182568:SU48_RS11760
uniprot id: A0A172TBD5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1182568:SU48 RS03000
gene id: 1182568:SU48_RS03000
uniprot id: A0A172T777
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS00130
gene id: 1182568:SU48_RS00130
uniprot id: A0A172T5X1
names: Similarity
messages: Belongs to the SufE family.

1182568:SU48 RS11290
gene id: 1182568:SU48_RS11290
uniprot id: A0A172TB93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1182568:SU48 RS10945
gene id: 1182568:SU48_RS10945
uniprot id: A0A172TD37
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1182568:SU48 RS03120
gene id: 1182568:SU48_RS03120
uniprot id: A0A172T798
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1182568:SU48 RS05140
gene id: 1182568:SU48_RS05140
uniprot id: A0A172T8I4
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1182568:SU48 RS02615
gene id: 1182568:SU48_RS02615
uniprot id: A0A172T7D2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1182568:SU48 RS01235
gene id: 1182568:SU48_RS01235
uniprot id: A0A172TCD8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1182568:SU48 RS12785
gene id: 1182568:SU48_RS12785
uniprot id: A0A172TC00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1182568:SU48 RS02425
gene id: 1182568:SU48_RS02425
uniprot id: A0A172T782
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1182568:SU48 RS02055
gene id: 1182568:SU48_RS02055
uniprot id: A0A172T6X8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1182568:SU48 RS03370
gene id: 1182568:SU48_RS03370
uniprot id: A0A172T7G4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1182568:SU48 RS02435
gene id: 1182568:SU48_RS02435
uniprot id: A0A172T704
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1182568:SU48 RS12985
gene id: 1182568:SU48_RS12985
uniprot id: A0A172TBU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1182568:SU48 RS03545
gene id: 1182568:SU48_RS03545
uniprot id: A0A172T7S6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1182568:SU48 RS04290
gene id: 1182568:SU48_RS04290
uniprot id: A0A172TCP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06775
gene id: 1182568:SU48_RS06775
uniprot id: A0A172T996
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1182568:SU48 RS00450
gene id: 1182568:SU48_RS00450
uniprot id: A0A172T6P1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1182568:SU48 RS09565
gene id: 1182568:SU48_RS09565
uniprot id: A0A172TAK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS11245
gene id: 1182568:SU48_RS11245
uniprot id: A0A172TBR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1182568:SU48 RS01995
gene id: 1182568:SU48_RS01995
uniprot id: A0A172T6W8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1182568:SU48 RS11015
gene id: 1182568:SU48_RS11015
uniprot id: A0A172TBB1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1182568:SU48 RS04120
gene id: 1182568:SU48_RS04120
uniprot id: A0A172T7Y0
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1182568:SU48 RS09070
gene id: 1182568:SU48_RS09070
uniprot id: A0A172TAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1182568:SU48 RS12100
gene id: 1182568:SU48_RS12100
uniprot id: A0A172TBN4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1182568:SU48 RS05450
gene id: 1182568:SU48_RS05450
uniprot id: A0A172T8N6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1182568:SU48 RS08595
gene id: 1182568:SU48_RS08595
uniprot id: A0A172TA68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1182568:SU48 RS07135
gene id: 1182568:SU48_RS07135
uniprot id: A0A172T9A9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06795
gene id: 1182568:SU48_RS06795
uniprot id: A0A172T9A8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS00420
gene id: 1182568:SU48_RS00420
uniprot id: A0A172T620
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1182568:SU48 RS13610
gene id: 1182568:SU48_RS13610
uniprot id: A0A172TCG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1182568:SU48 RS02755
gene id: 1182568:SU48_RS02755
uniprot id: A0A172T7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1182568:SU48 RS10210
gene id: 1182568:SU48_RS10210
uniprot id: A0A172TAN0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1182568:SU48 RS05575
gene id: 1182568:SU48_RS05575
uniprot id: A0A172T8Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1182568:SU48 RS10715
gene id: 1182568:SU48_RS10715
uniprot id: A0A172TB37
names: Similarity
messages: Belongs to the DinB family.

1182568:SU48 RS00925
gene id: 1182568:SU48_RS00925
uniprot id: A0A172T696
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1182568:SU48 RS07175
gene id: 1182568:SU48_RS07175
uniprot id: A0A172T9H0
names: Similarity
messages: Belongs to the peptidase C40 family.

1182568:SU48 RS00310
gene id: 1182568:SU48_RS00310
uniprot id: A0A172T660
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS10010
gene id: 1182568:SU48_RS10010
uniprot id: A0A172TAK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1182568:SU48 RS11180
gene id: 1182568:SU48_RS11180
uniprot id: A0A172TBC4
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS03380
gene id: 1182568:SU48_RS03380
uniprot id: A0A172T7K3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1182568:SU48 RS09340
gene id: 1182568:SU48_RS09340
uniprot id: A0A172TAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS04500
gene id: 1182568:SU48_RS04500
uniprot id: A0A172T841
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS04090
gene id: 1182568:SU48_RS04090
uniprot id: A0A172T811
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS12965
gene id: 1182568:SU48_RS12965
uniprot id: A0A172TC08
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS00200
gene id: 1182568:SU48_RS00200
uniprot id: A0A172T637
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1182568:SU48 RS06495
gene id: 1182568:SU48_RS06495
uniprot id: A0A172T8X1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1182568:SU48 RS09900
gene id: 1182568:SU48_RS09900
uniprot id: A0A172TAI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS02835
gene id: 1182568:SU48_RS02835
uniprot id: A0A172T769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS10120
gene id: 1182568:SU48_RS10120
uniprot id: A0A172TB79
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1182568:SU48 RS11340
gene id: 1182568:SU48_RS11340
uniprot id: A0A172TB53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1182568:SU48 RS03980
gene id: 1182568:SU48_RS03980
uniprot id: A0A172T7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1182568:SU48 RS01705
gene id: 1182568:SU48_RS01705
uniprot id: A0A172T6U5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1182568:SU48 RS07925
gene id: 1182568:SU48_RS07925
uniprot id: A0A172T9K5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1182568:SU48 RS06915
gene id: 1182568:SU48_RS06915
uniprot id: A0A172T942
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1182568:SU48 RS10710
gene id: 1182568:SU48_RS10710
uniprot id: A0A172TAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1182568:SU48 RS06970
gene id: 1182568:SU48_RS06970
uniprot id: A0A172T9B9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1182568:SU48 RS10140
gene id: 1182568:SU48_RS10140
uniprot id: A0A172TAW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1182568:SU48 RS05790
gene id: 1182568:SU48_RS05790
uniprot id: A0A172T8K8
names: Similarity
messages: Belongs to the RelA/SpoT family.

1182568:SU48 RS06490
gene id: 1182568:SU48_RS06490
uniprot id: A0A172T952
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS08495
gene id: 1182568:SU48_RS08495
uniprot id: A0A172T9X5
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS09220
gene id: 1182568:SU48_RS09220
uniprot id: A0A172TA72
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1182568:SU48 RS05840
gene id: 1182568:SU48_RS05840
uniprot id: A0A172T8U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1182568:SU48 RS08580
gene id: 1182568:SU48_RS08580
uniprot id: A0A172TA46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1182568:SU48 RS03285
gene id: 1182568:SU48_RS03285
uniprot id: A0A172T7C9
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

1182568:SU48 RS07240
gene id: 1182568:SU48_RS07240
uniprot id: A0A172T9I0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS12365
gene id: 1182568:SU48_RS12365
uniprot id: A0A172TBU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1182568:SU48 RS10585
gene id: 1182568:SU48_RS10585
uniprot id: A0A172TB50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1182568:SU48 RS06000
gene id: 1182568:SU48_RS06000
uniprot id: A0A172T8P0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1182568:SU48 RS09005
gene id: 1182568:SU48_RS09005
uniprot id: A0A172TAC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS04740
gene id: 1182568:SU48_RS04740
uniprot id: A0A172T875
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1182568:SU48 RS12390
gene id: 1182568:SU48_RS12390
uniprot id: A0A172TBP6
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS08940
gene id: 1182568:SU48_RS08940
uniprot id: A0A172TA34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1182568:SU48 RS11375
gene id: 1182568:SU48_RS11375
uniprot id: A0A172TBD4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1182568:SU48 RS08270
gene id: 1182568:SU48_RS08270
uniprot id: A0A172TAD9
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS03505
gene id: 1182568:SU48_RS03505
uniprot id: A0A172T7S4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1182568:SU48 RS09745
gene id: 1182568:SU48_RS09745
uniprot id: A0A172TAR8
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1182568:SU48 RS00230
gene id: 1182568:SU48_RS00230
uniprot id: A0A172T669
names: Similarity
messages: Belongs to the peptidase S13 family.

1182568:SU48 RS01035
gene id: 1182568:SU48_RS01035
uniprot id: A0A172T6C8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1182568:SU48 RS01765
gene id: 1182568:SU48_RS01765
uniprot id: A0A172TCL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1182568:SU48 RS13495
gene id: 1182568:SU48_RS13495
uniprot id: A0A172TCH3
names: Similarity
messages: Belongs to the Dps family.

1182568:SU48 RS09600
gene id: 1182568:SU48_RS09600
uniprot id: A0A172TAE4
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS12890
gene id: 1182568:SU48_RS12890
uniprot id: A0A172TBU9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1182568:SU48 RS08655
gene id: 1182568:SU48_RS08655
uniprot id: A0A172T9X7
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS04800
gene id: 1182568:SU48_RS04800
uniprot id: A0A172T840
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1182568:SU48 RS04075
gene id: 1182568:SU48_RS04075
uniprot id: A0A172T7V9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS06315
gene id: 1182568:SU48_RS06315
uniprot id: A0A172T8U0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1182568:SU48 RS03425
gene id: 1182568:SU48_RS03425
uniprot id: A0A172T7G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1182568:SU48 RS11450
gene id: 1182568:SU48_RS11450
uniprot id: A0A172TB95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1182568:SU48 RS02390
gene id: 1182568:SU48_RS02390
uniprot id: A0A172T768
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1182568:SU48 RS00505
gene id: 1182568:SU48_RS00505
uniprot id: A0A172T689
names: Similarity
messages: Belongs to the ParB family.

1182568:SU48 RS11425
gene id: 1182568:SU48_RS11425
uniprot id: A0A172TAU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1182568:SU48 RS06590
gene id: 1182568:SU48_RS06590
uniprot id: A0A172T9K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1182568:SU48 RS06370
gene id: 1182568:SU48_RS06370
uniprot id: A0A172T934
names: Similarity
messages: Belongs to the peptidase S8 family.

1182568:SU48 RS00180
gene id: 1182568:SU48_RS00180
uniprot id: A0A172T658
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1182568:SU48 RS13150
gene id: 1182568:SU48_RS13150
uniprot id: A0A172TCM6
names: Similarity
messages: Belongs to the Nth/MutY family.

1182568:SU48 RS08280
gene id: 1182568:SU48_RS08280
uniprot id: A0A172T9S6
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS03725
gene id: 1182568:SU48_RS03725
uniprot id: A0A172T7L8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1182568:SU48 RS04100
gene id: 1182568:SU48_RS04100
uniprot id: A0A172T816
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1182568:SU48 RS00010
gene id: 1182568:SU48_RS00010
uniprot id: A0A172T631
names: Similarity
messages: Belongs to the GSP E family.

1182568:SU48 RS03170
gene id: 1182568:SU48_RS03170
uniprot id: A0A172T7L6
names: Similarity
messages: Belongs to the asp23 family.

1182568:SU48 RS11175
gene id: 1182568:SU48_RS11175
uniprot id: A0A172TBQ8
names: Similarity
messages: Belongs to the ribF family.

1182568:SU48 RS12035
gene id: 1182568:SU48_RS12035
uniprot id: A0A172TC41
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1182568:SU48 RS08930
gene id: 1182568:SU48_RS08930
uniprot id: A0A172TAP7
names: Similarity
messages: Belongs to the TrpC family.

1182568:SU48 RS01780
gene id: 1182568:SU48_RS01780
uniprot id: A0A172T6W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1182568:SU48 RS11315
gene id: 1182568:SU48_RS11315
uniprot id: A0A172TBC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1182568:SU48 RS06295
gene id: 1182568:SU48_RS06295
uniprot id: A0A172T9F4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS11215
gene id: 1182568:SU48_RS11215
uniprot id: A0A172TB35
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS10470
gene id: 1182568:SU48_RS10470
uniprot id: A0A172TAS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS07905
gene id: 1182568:SU48_RS07905
uniprot id: A0A172TCV5
names: Similarity
messages: Belongs to the peptidase S41A family.

1182568:SU48 RS07000
gene id: 1182568:SU48_RS07000
uniprot id: A0A172T9E1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1182568:SU48 RS12625
gene id: 1182568:SU48_RS12625
uniprot id: A0A172TC06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1182568:SU48 RS04425
gene id: 1182568:SU48_RS04425
uniprot id: A0A172T7X7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1182568:SU48 RS12970
gene id: 1182568:SU48_RS12970
uniprot id: A0A172TC36
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1182568:SU48 RS09655
gene id: 1182568:SU48_RS09655
uniprot id: A0A172TAF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06630
gene id: 1182568:SU48_RS06630
uniprot id: A0A172T8Y7
names: Similarity
messages: Belongs to the MreC family.

1182568:SU48 RS06115
gene id: 1182568:SU48_RS06115
uniprot id: A0A172T9C2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1182568:SU48 RS00445
gene id: 1182568:SU48_RS00445
uniprot id: A0A172T693
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1182568:SU48 RS13190
gene id: 1182568:SU48_RS13190
uniprot id: A0A172TDH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1182568:SU48 RS04170
gene id: 1182568:SU48_RS04170
uniprot id: A0A172T7U3
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

1182568:SU48 RS06110
gene id: 1182568:SU48_RS06110
uniprot id: A0A172T8Y1
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS11585
gene id: 1182568:SU48_RS11585
uniprot id: A0A172TBF2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1182568:SU48 RS01475
gene id: 1182568:SU48_RS01475
uniprot id: A0A172T6R5
names: Similarity
messages: Belongs to the CutA family.

1182568:SU48 RS08285
gene id: 1182568:SU48_RS08285
uniprot id: A0A172TA12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
messages: Cytoplasm

1182568:SU48 RS10680
gene id: 1182568:SU48_RS10680
uniprot id: A0A172TAX1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.

1182568:SU48 RS09960
gene id: 1182568:SU48_RS09960
uniprot id: A0A172TD21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1182568:SU48 RS07170
gene id: 1182568:SU48_RS07170
uniprot id: A0A172T9G9
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1182568:SU48 RS13355
gene id: 1182568:SU48_RS13355
uniprot id: A0A172TCC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1182568:SU48 RS07280
gene id: 1182568:SU48_RS07280
uniprot id: A0A172T9H7
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS06685
gene id: 1182568:SU48_RS06685
uniprot id: A0A172T993
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1182568:SU48 RS12765
gene id: 1182568:SU48_RS12765
uniprot id: A0A172TBT0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1182568:SU48 RS02310
gene id: 1182568:SU48_RS02310
uniprot id: A0A172T6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1182568:SU48 RS02550
gene id: 1182568:SU48_RS02550
uniprot id: A0A172T703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1182568:SU48 RS01215
gene id: 1182568:SU48_RS01215
uniprot id: A0A172T6P4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1182568:SU48 RS11280
gene id: 1182568:SU48_RS11280
uniprot id: A0A172TB41
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1182568:SU48 RS08155
gene id: 1182568:SU48_RS08155
uniprot id: A0A172T9S0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1182568:SU48 RS10350
gene id: 1182568:SU48_RS10350
uniprot id: A0A172TAQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1182568:SU48 RS11905
gene id: 1182568:SU48_RS11905
uniprot id: A0A172TBG7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1182568:SU48 RS03090
gene id: 1182568:SU48_RS03090
uniprot id: A0A172T7B5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1182568:SU48 RS01455
gene id: 1182568:SU48_RS01455
uniprot id: A0A172T6I9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1182568:SU48 RS13725
gene id: 1182568:SU48_RS13725
uniprot id: A0A172TCI2
names: Similarity
messages: Belongs to the peptidase S66 family.

1182568:SU48 RS10655
gene id: 1182568:SU48_RS10655
uniprot id: A0A172TB60
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1182568:SU48 RS03740
gene id: 1182568:SU48_RS03740
uniprot id: A0A172T7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1182568:SU48 RS12850
gene id: 1182568:SU48_RS12850
uniprot id: A0A172TC44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1182568:SU48 RS07340
gene id: 1182568:SU48_RS07340
uniprot id: A0A172T9K0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1182568:SU48 RS08880
gene id: 1182568:SU48_RS08880
uniprot id: A0A172TD57
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1182568:SU48 RS07960
gene id: 1182568:SU48_RS07960
uniprot id: A0A172T9L5
names: Similarity
messages: Belongs to the peptidase M29 family.

1182568:SU48 RS10355
gene id: 1182568:SU48_RS10355
uniprot id: A0A172TAR1
names: Similarity
messages: Belongs to the PstS family.

1182568:SU48 RS08000
gene id: 1182568:SU48_RS08000
uniprot id: A0A172T9T7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1182568:SU48 RS08385
gene id: 1182568:SU48_RS08385
uniprot id: A0A172TA18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1182568:SU48 RS09720
gene id: 1182568:SU48_RS09720
uniprot id: A0A172TAM5
names: Similarity
messages: Belongs to the threonine aldolase family.

1182568:SU48 RS01920
gene id: 1182568:SU48_RS01920
uniprot id: A0A172T6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1182568:SU48 RS02025
gene id: 1182568:SU48_RS02025
uniprot id: A0A172T6R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS04280
gene id: 1182568:SU48_RS04280
uniprot id: A0A172T848
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1182568:SU48 RS02855
gene id: 1182568:SU48_RS02855
uniprot id: A0A172T7B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1182568:SU48 RS04615
gene id: 1182568:SU48_RS04615
uniprot id: A0A172T858
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1182568:SU48 RS09990
gene id: 1182568:SU48_RS09990
uniprot id: A0A172TAJ3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1182568:SU48 RS08730
gene id: 1182568:SU48_RS08730
uniprot id: A0A172TA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS01760
gene id: 1182568:SU48_RS01760
uniprot id: A0A172T6V5
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS06910
gene id: 1182568:SU48_RS06910
uniprot id: A0A172T9B6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1182568:SU48 RS10375
gene id: 1182568:SU48_RS10375
uniprot id: A0A172TAZ0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1182568:SU48 RS00080
gene id: 1182568:SU48_RS00080
uniprot id: A0A172T615
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1182568:SU48 RS10565
gene id: 1182568:SU48_RS10565
uniprot id: A0A172TBF7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1182568:SU48 RS08530
gene id: 1182568:SU48_RS08530
uniprot id: A0A172TA53
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS05155
gene id: 1182568:SU48_RS05155
uniprot id: A0A172T8A7
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS02300
gene id: 1182568:SU48_RS02300
uniprot id: A0A172T762
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1182568:SU48 RS06715
gene id: 1182568:SU48_RS06715
uniprot id: A0A172T9M8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS05820
gene id: 1182568:SU48_RS05820
uniprot id: A0A172T8U5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1182568:SU48 RS08110
gene id: 1182568:SU48_RS08110
uniprot id: A0A172T9V6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1182568:SU48 RS11075
gene id: 1182568:SU48_RS11075
uniprot id: A0A172TBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1182568:SU48 RS07820
gene id: 1182568:SU48_RS07820
uniprot id: A0A172T9Q3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1182568:SU48 RS09355
gene id: 1182568:SU48_RS09355
uniprot id: A0A172TAG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS12540
gene id: 1182568:SU48_RS12540
uniprot id: A0A172TBN3
names: Similarity
messages: Belongs to the UbiD family.

1182568:SU48 RS09235
gene id: 1182568:SU48_RS09235
uniprot id: A0A172TA85
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1182568:SU48 RS09920
gene id: 1182568:SU48_RS09920
uniprot id: A0A172TAS7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1182568:SU48 RS13385
gene id: 1182568:SU48_RS13385
uniprot id: A0A172TCE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1182568:SU48 RS01015
gene id: 1182568:SU48_RS01015
uniprot id: A0A172T6A8
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS06100
gene id: 1182568:SU48_RS06100
uniprot id: A0A172T8R9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1182568:SU48 RS08990
gene id: 1182568:SU48_RS08990
uniprot id: A0A172TAQ6
names: Similarity
messages: Belongs to the peptidase S1C family.

1182568:SU48 RS10910
gene id: 1182568:SU48_RS10910
uniprot id: A0A172TAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1182568:SU48 RS03880
gene id: 1182568:SU48_RS03880
uniprot id: A0A172T7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1182568:SU48 RS11545
gene id: 1182568:SU48_RS11545
uniprot id: A0A172TD69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1182568:SU48 RS01125
gene id: 1182568:SU48_RS01125
uniprot id: A0A172T702
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1182568:SU48 RS04730
gene id: 1182568:SU48_RS04730
uniprot id: A0A172T832
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1182568:SU48 RS11350
gene id: 1182568:SU48_RS11350
uniprot id: A0A172TBA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1182568:SU48 RS12975
gene id: 1182568:SU48_RS12975
uniprot id: A0A172TCJ3
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1182568:SU48 RS00895
gene id: 1182568:SU48_RS00895
uniprot id: A0A172T6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1182568:SU48 RS10280
gene id: 1182568:SU48_RS10280
uniprot id: A0A172TAQ4
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1182568:SU48 RS00425
gene id: 1182568:SU48_RS00425
uniprot id: A0A172T617
names: Similarity
messages: Belongs to the DprA/Smf family.

1182568:SU48 RS05280
gene id: 1182568:SU48_RS05280
uniprot id: A0A172T8E9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1182568:SU48 RS02215
gene id: 1182568:SU48_RS02215
uniprot id: A0A172T710
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1182568:SU48 RS05355
gene id: 1182568:SU48_RS05355
uniprot id: A0A172T8H1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1182568:SU48 RS07560
gene id: 1182568:SU48_RS07560
uniprot id: A0A172T9L6
names: Similarity
messages: Belongs to the histone deacetylase family.

1182568:SU48 RS07840
gene id: 1182568:SU48_RS07840
uniprot id: A0A172T9R3
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS05320
gene id: 1182568:SU48_RS05320
uniprot id: A0A172T8L6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1182568:SU48 RS11370
gene id: 1182568:SU48_RS11370
uniprot id: A0A172TB38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1182568:SU48 RS00190
gene id: 1182568:SU48_RS00190
uniprot id: A0A172T5X6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1182568:SU48 RS09330
gene id: 1182568:SU48_RS09330
uniprot id: A0A172TAJ6
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1182568:SU48 RS08820
gene id: 1182568:SU48_RS08820
uniprot id: A0A172TAA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1182568:SU48 RS13380
gene id: 1182568:SU48_RS13380
uniprot id: A0A172TCA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS07105
gene id: 1182568:SU48_RS07105
uniprot id: A0A172T974
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1182568:SU48 RS00785
gene id: 1182568:SU48_RS00785
uniprot id: A0A172T6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1182568:SU48 RS11275
gene id: 1182568:SU48_RS11275
uniprot id: A0A172TB52
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1182568:SU48 RS13475
gene id: 1182568:SU48_RS13475
uniprot id: A0A172TCT2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1182568:SU48 RS04585
gene id: 1182568:SU48_RS04585
uniprot id: A0A172T898
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1182568:SU48 RS02010
gene id: 1182568:SU48_RS02010
uniprot id: A0A172T7D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1182568:SU48 RS08790
gene id: 1182568:SU48_RS08790
uniprot id: A0A172TA25
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS07880
gene id: 1182568:SU48_RS07880
uniprot id: A0A172T9M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1182568:SU48 RS10135
gene id: 1182568:SU48_RS10135
uniprot id: A0A172TAW4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1182568:SU48 RS11050
gene id: 1182568:SU48_RS11050
uniprot id: A0A172TBN7
names: Subcellular Location Annotation
messages: Nucleus

1182568:SU48 RS05145
gene id: 1182568:SU48_RS05145
uniprot id: A0A172T8I7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS10220
gene id: 1182568:SU48_RS10220
uniprot id: A0A172TAP4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1182568:SU48 RS08855
gene id: 1182568:SU48_RS08855
uniprot id: A0A172TA78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1182568:SU48 RS01255
gene id: 1182568:SU48_RS01255
uniprot id: A0A172T722
names: Similarity
messages: Belongs to the peptidase M29 family.

1182568:SU48 RS00825
gene id: 1182568:SU48_RS00825
uniprot id: A0A172T6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS03790
gene id: 1182568:SU48_RS03790
uniprot id: A0A172TCX0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1182568:SU48 RS05490
gene id: 1182568:SU48_RS05490
uniprot id: A0A172T8G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1182568:SU48 RS05115
gene id: 1182568:SU48_RS05115
uniprot id: A0A172T8H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1182568:SU48 RS09480
gene id: 1182568:SU48_RS09480
uniprot id: A0A172TAY3
names: Similarity
messages: Belongs to the RecJ family.

1182568:SU48 RS10810
gene id: 1182568:SU48_RS10810
uniprot id: A0A172TB22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1182568:SU48 RS04140
gene id: 1182568:SU48_RS04140
uniprot id: A0A172T820
names: Similarity
messages: Belongs to the peptidase S8 family.

1182568:SU48 RS03160
gene id: 1182568:SU48_RS03160
uniprot id: A0A172T7Y2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1182568:SU48 RS01430
gene id: 1182568:SU48_RS01430
uniprot id: A0A172T6R3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1182568:SU48 RS11355
gene id: 1182568:SU48_RS11355
uniprot id: A0A172TBB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1182568:SU48 RS05285
gene id: 1182568:SU48_RS05285
uniprot id: A0A172T8F9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1182568:SU48 RS06585
gene id: 1182568:SU48_RS06585
uniprot id: A0A172T961
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1182568:SU48 RS13285
gene id: 1182568:SU48_RS13285
uniprot id: A0A172TDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1182568:SU48 RS07910
gene id: 1182568:SU48_RS07910
uniprot id: A0A172T9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1182568:SU48 RS02955
gene id: 1182568:SU48_RS02955
uniprot id: A0A172T795
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1182568:SU48 RS02685
gene id: 1182568:SU48_RS02685
uniprot id: A0A172T788
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS11295
gene id: 1182568:SU48_RS11295
uniprot id: A0A172TBA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1182568:SU48 RS05055
gene id: 1182568:SU48_RS05055
uniprot id: A0A172T8C5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1182568:SU48 RS10105
gene id: 1182568:SU48_RS10105
uniprot id: A0A172TDQ1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1182568:SU48 RS01955
gene id: 1182568:SU48_RS01955
uniprot id: A0A172T719
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1182568:SU48 RS02735
gene id: 1182568:SU48_RS02735
uniprot id: A0A172T7A0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1182568:SU48 RS13180
gene id: 1182568:SU48_RS13180
uniprot id: A0A172TC05
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1182568:SU48 RS10825
gene id: 1182568:SU48_RS10825
uniprot id: A0A172TB78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS12215
gene id: 1182568:SU48_RS12215
uniprot id: A0A172TBI3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS03125
gene id: 1182568:SU48_RS03125
uniprot id: A0A172T7L7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1182568:SU48 RS12740
gene id: 1182568:SU48_RS12740
uniprot id: A0A172TC23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1182568:SU48 RS00490
gene id: 1182568:SU48_RS00490
uniprot id: A0A172T630
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1182568:SU48 RS05050
gene id: 1182568:SU48_RS05050
uniprot id: A0A172T8B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1182568:SU48 RS10760
gene id: 1182568:SU48_RS10760
uniprot id: A0A172TDA4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS02285
gene id: 1182568:SU48_RS02285
uniprot id: A0A172TCM5
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS12900
gene id: 1182568:SU48_RS12900
uniprot id: A0A172TD63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS02315
gene id: 1182568:SU48_RS02315
uniprot id: A0A172T731
names: Similarity
messages: Belongs to the peptidase M16 family.

1182568:SU48 RS04595
gene id: 1182568:SU48_RS04595
uniprot id: A0A172TCL0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1182568:SU48 RS12990
gene id: 1182568:SU48_RS12990
uniprot id: A0A172TC47
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1182568:SU48 RS12195
gene id: 1182568:SU48_RS12195
uniprot id: A0A172TBR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS01355
gene id: 1182568:SU48_RS01355
uniprot id: A0A172T6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS13700
gene id: 1182568:SU48_RS13700
uniprot id: A0A172TC88
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1182568:SU48 RS13390
gene id: 1182568:SU48_RS13390
uniprot id: A0A172TC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS06650
gene id: 1182568:SU48_RS06650
uniprot id: A0A172T931
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1182568:SU48 RS04515
gene id: 1182568:SU48_RS04515
uniprot id: A0A172T868
names: Similarity
messages: Belongs to the barstar family.

1182568:SU48 RS10955
gene id: 1182568:SU48_RS10955
uniprot id: A0A172TB58
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1182568:SU48 RS04855
gene id: 1182568:SU48_RS04855
uniprot id: A0A172T8D2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1182568:SU48 RS02985
gene id: 1182568:SU48_RS02985
uniprot id: A0A172T7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1182568:SU48 RS05645
gene id: 1182568:SU48_RS05645
uniprot id: A0A172T8R2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1182568:SU48 RS09790
gene id: 1182568:SU48_RS09790
uniprot id: A0A172TAN4
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS05135
gene id: 1182568:SU48_RS05135
uniprot id: A0A172T8A0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1182568:SU48 RS06325
gene id: 1182568:SU48_RS06325
uniprot id: A0A172T929
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1182568:SU48 RS11335
gene id: 1182568:SU48_RS11335
uniprot id: A0A172TB61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1182568:SU48 RS05690
gene id: 1182568:SU48_RS05690
uniprot id: A0A172T8J1
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS07085
gene id: 1182568:SU48_RS07085
uniprot id: A0A172T997
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS06850
gene id: 1182568:SU48_RS06850
uniprot id: A0A172T928
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1182568:SU48 RS11930
gene id: 1182568:SU48_RS11930
uniprot id: A0A172TBC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1182568:SU48 RS10410
gene id: 1182568:SU48_RS10410
uniprot id: A0A172TAR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1182568:SU48 RS01310
gene id: 1182568:SU48_RS01310
uniprot id: A0A172T732
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1182568:SU48 RS10505
gene id: 1182568:SU48_RS10505
uniprot id: A0A172TBE4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1182568:SU48 RS11940
gene id: 1182568:SU48_RS11940
uniprot id: A0A172TBQ6
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS04450
gene id: 1182568:SU48_RS04450
uniprot id: A0A172T863
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS12360
gene id: 1182568:SU48_RS12360
uniprot id: A0A172TBK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1182568:SU48 RS01245
gene id: 1182568:SU48_RS01245
uniprot id: A0A172T6J9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1182568:SU48 RS00455
gene id: 1182568:SU48_RS00455
uniprot id: A0A172T6A5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1182568:SU48 RS08460
gene id: 1182568:SU48_RS08460
uniprot id: A0A172TA48
names: Similarity
messages: Belongs to the peptidase S1B family.

1182568:SU48 RS10455
gene id: 1182568:SU48_RS10455
uniprot id: A0A172TAR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1182568:SU48 RS08550
gene id: 1182568:SU48_RS08550
uniprot id: A0A172T9X3
names: Similarity
messages: Belongs to the cytochrome b560 family.

1182568:SU48 RS10130
gene id: 1182568:SU48_RS10130
uniprot id: A0A172TAL4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS08725
gene id: 1182568:SU48_RS08725
uniprot id: A0A172TA11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS04755
gene id: 1182568:SU48_RS04755
uniprot id: A0A172T8R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1182568:SU48 RS05345
gene id: 1182568:SU48_RS05345
uniprot id: A0A172T8D7
names: Similarity
messages: Belongs to the peptidase S8 family.

1182568:SU48 RS11485
gene id: 1182568:SU48_RS11485
uniprot id: A0A172TB54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1182568:SU48 RS11765
gene id: 1182568:SU48_RS11765
uniprot id: A0A172TBC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1182568:SU48 RS11365
gene id: 1182568:SU48_RS11365
uniprot id: A0A172TBF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1182568:SU48 RS12300
gene id: 1182568:SU48_RS12300
uniprot id: A0A172TC80
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1182568:SU48 RS03395
gene id: 1182568:SU48_RS03395
uniprot id: A0A172T824
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS11550
gene id: 1182568:SU48_RS11550
uniprot id: A0A172TBJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1182568:SU48 RS05600
gene id: 1182568:SU48_RS05600
uniprot id: A0A172TCL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1182568:SU48 RS05025
gene id: 1182568:SU48_RS05025
uniprot id: A0A172T8G5
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS06995
gene id: 1182568:SU48_RS06995
uniprot id: A0A172T9D9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1182568:SU48 RS07455
gene id: 1182568:SU48_RS07455
uniprot id: A0A172T9M4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1182568:SU48 RS05555
gene id: 1182568:SU48_RS05555
uniprot id: A0A172T8P5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1182568:SU48 RS07980
gene id: 1182568:SU48_RS07980
uniprot id: A0A172T9L4
names: Similarity
messages: Belongs to the histone deacetylase family.

1182568:SU48 RS11750
gene id: 1182568:SU48_RS11750
uniprot id: A0A172TBM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1182568:SU48 RS02975
gene id: 1182568:SU48_RS02975
uniprot id: A0A172T7G8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1182568:SU48 RS04440
gene id: 1182568:SU48_RS04440
uniprot id: A0A172T817
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Cytoplasm
messages: Homodimer.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1182568:SU48 RS04835
gene id: 1182568:SU48_RS04835
uniprot id: A0A172T8S1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS13220
gene id: 1182568:SU48_RS13220
uniprot id: A0A172TCN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1182568:SU48 RS08890
gene id: 1182568:SU48_RS08890
uniprot id: A0A172TA24
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1182568:SU48 RS02205
gene id: 1182568:SU48_RS02205
uniprot id: A0A172T6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1182568:SU48 RS03280
gene id: 1182568:SU48_RS03280
uniprot id: A0A172T7N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS07200
gene id: 1182568:SU48_RS07200
uniprot id: A0A172T9B5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1182568:SU48 RS06105
gene id: 1182568:SU48_RS06105
uniprot id: A0A172T8U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1182568:SU48 RS09075
gene id: 1182568:SU48_RS09075
uniprot id: A0A172TA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1182568:SU48 RS08085
gene id: 1182568:SU48_RS08085
uniprot id: A0A172T9X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1182568:SU48 RS04650
gene id: 1182568:SU48_RS04650
uniprot id: A0A172T897
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1182568:SU48 RS13335
gene id: 1182568:SU48_RS13335
uniprot id: A0A172TC94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1182568:SU48 RS03330
gene id: 1182568:SU48_RS03330
uniprot id: A0A172T7N2
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1182568:SU48 RS02630
gene id: 1182568:SU48_RS02630
uniprot id: A0A172T735
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1182568:SU48 RS12825
gene id: 1182568:SU48_RS12825
uniprot id: A0A172TBU1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1182568:SU48 RS04610
gene id: 1182568:SU48_RS04610
uniprot id: A0A172T862
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1182568:SU48 RS11415
gene id: 1182568:SU48_RS11415
uniprot id: A0A172TBU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1182568:SU48 RS00365
gene id: 1182568:SU48_RS00365
uniprot id: A0A172T607
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS05940
gene id: 1182568:SU48_RS05940
uniprot id: A0A172T8M9
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS00900
gene id: 1182568:SU48_RS00900
uniprot id: A0A172T688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1182568:SU48 RS09580
gene id: 1182568:SU48_RS09580
uniprot id: A0A172TAN6
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1182568:SU48 RS08305
gene id: 1182568:SU48_RS08305
uniprot id: A0A172T9T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1182568:SU48 RS03405
gene id: 1182568:SU48_RS03405
uniprot id: A0A172T7Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1182568:SU48 RS01350
gene id: 1182568:SU48_RS01350
uniprot id: A0A172T6M4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1182568:SU48 RS00090
gene id: 1182568:SU48_RS00090
uniprot id: A0A172T636
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1182568:SU48 RS09060
gene id: 1182568:SU48_RS09060
uniprot id: A0A172TDA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1182568:SU48 RS08610
gene id: 1182568:SU48_RS08610
uniprot id: A0A172T9Z1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS05630
gene id: 1182568:SU48_RS05630
uniprot id: A0A172T8R6
names: Similarity
messages: Belongs to the TelA family.

1182568:SU48 RS02920
gene id: 1182568:SU48_RS02920
uniprot id: A0A172T7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1182568:SU48 RS12265
gene id: 1182568:SU48_RS12265
uniprot id: A0A172TBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS02875
gene id: 1182568:SU48_RS02875
uniprot id: A0A172T761
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1182568:SU48 RS01805
gene id: 1182568:SU48_RS01805
uniprot id: A0A172T6P6
names: Similarity
messages: Belongs to the peptidase S8 family.

1182568:SU48 RS05735
gene id: 1182568:SU48_RS05735
uniprot id: A0A172T8S3
names: Subcellular Location Annotation
messages: Cytoplasm

1182568:SU48 RS10060
gene id: 1182568:SU48_RS10060
uniprot id: A0A172TAU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1182568:SU48 RS08025
gene id: 1182568:SU48_RS08025
uniprot id: A0A172T9W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1182568:SU48 RS10260
gene id: 1182568:SU48_RS10260
uniprot id: A0A172TAY0
names: Similarity
messages: Belongs to the Skp family.

1182568:SU48 RS02250
gene id: 1182568:SU48_RS02250
uniprot id: A0A172T6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1182568:SU48 RS07470
gene id: 1182568:SU48_RS07470
uniprot id: A0A172T9E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS03830
gene id: 1182568:SU48_RS03830
uniprot id: A0A172T899
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS11410
gene id: 1182568:SU48_RS11410
uniprot id: A0A172TBC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1182568:SU48 RS08985
gene id: 1182568:SU48_RS08985
uniprot id: A0A172TA97
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1182568:SU48 RS07790
gene id: 1182568:SU48_RS07790
uniprot id: A0A172T9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1182568:SU48 RS01755
gene id: 1182568:SU48_RS01755
uniprot id: A0A172T6T2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS10740
gene id: 1182568:SU48_RS10740
uniprot id: A0A172TB04
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1182568:SU48 RS01220
gene id: 1182568:SU48_RS01220
uniprot id: A0A172T6N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1182568:SU48 RS03655
gene id: 1182568:SU48_RS03655
uniprot id: A0A172TCI8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1182568:SU48 RS10115
gene id: 1182568:SU48_RS10115
uniprot id: A0A172TAT1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1182568:SU48 RS02230
gene id: 1182568:SU48_RS02230
uniprot id: A0A172T749
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS07550
gene id: 1182568:SU48_RS07550
uniprot id: A0A172T9H8
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS13250
gene id: 1182568:SU48_RS13250
uniprot id: A0A172TC16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1182568:SU48 RS12385
gene id: 1182568:SU48_RS12385
uniprot id: A0A172TBL2
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS06050
gene id: 1182568:SU48_RS06050
uniprot id: A0A172T9B4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1182568:SU48 RS07800
gene id: 1182568:SU48_RS07800
uniprot id: A0A172T9J3
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS05885
gene id: 1182568:SU48_RS05885
uniprot id: A0A172TCX7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1182568:SU48 RS05375
gene id: 1182568:SU48_RS05375
uniprot id: A0A172T8M5
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS00290
gene id: 1182568:SU48_RS00290
uniprot id: A0A172T5Z7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1182568:SU48 RS00335
gene id: 1182568:SU48_RS00335
uniprot id: A0A172T6L9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1182568:SU48 RS11150
gene id: 1182568:SU48_RS11150
uniprot id: A0A172TB24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1182568:SU48 RS10465
gene id: 1182568:SU48_RS10465
uniprot id: A0A172TB25
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1182568:SU48 RS00680
gene id: 1182568:SU48_RS00680
uniprot id: A0A172T6B9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1182568:SU48 RS11855
gene id: 1182568:SU48_RS11855
uniprot id: A0A172TDE2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1182568:SU48 RS02080
gene id: 1182568:SU48_RS02080
uniprot id: A0A172T6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1182568:SU48 RS00800
gene id: 1182568:SU48_RS00800
uniprot id: A0A172T675
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1182568:SU48 RS05475
gene id: 1182568:SU48_RS05475
uniprot id: A0A172T8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1182568:SU48 RS11915
gene id: 1182568:SU48_RS11915
uniprot id: A0A172TBL0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1182568:SU48 RS01440
gene id: 1182568:SU48_RS01440
uniprot id: A0A172T6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS10900
gene id: 1182568:SU48_RS10900
uniprot id: A0A172TB06
names: Similarity
messages: Belongs to the NAPRTase family.

1182568:SU48 RS08950
gene id: 1182568:SU48_RS08950
uniprot id: A0A172TAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1182568:SU48 RS02335
gene id: 1182568:SU48_RS02335
uniprot id: A0A172T7J6
names: Similarity
messages: Belongs to the Ahb/Nir family.

1182568:SU48 RS08650
gene id: 1182568:SU48_RS08650
uniprot id: A0A172TA76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1182568:SU48 RS05745
gene id: 1182568:SU48_RS05745
uniprot id: A0A172T972
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1182568:SU48 RS11955
gene id: 1182568:SU48_RS11955
uniprot id: A0A172TBH6
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1182568:SU48 RS11405
gene id: 1182568:SU48_RS11405
uniprot id: A0A172TBB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1182568:SU48 RS03700
gene id: 1182568:SU48_RS03700
uniprot id: A0A172T7K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1182568:SU48 RS08225
gene id: 1182568:SU48_RS08225
uniprot id: A0A172T9R7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1182568:SU48 RS08490
gene id: 1182568:SU48_RS08490
uniprot id: A0A172TCY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1182568:SU48 RS10240
gene id: 1182568:SU48_RS10240
uniprot id: A0A172TAX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1182568:SU48 RS05875
gene id: 1182568:SU48_RS05875
uniprot id: A0A172T8V6
names: Similarity
messages: Belongs to the peptidase C40 family.

1182568:SU48 RS02820
gene id: 1182568:SU48_RS02820
uniprot id: A0A172T7H4
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS03265
gene id: 1182568:SU48_RS03265
uniprot id: A0A172T7H9
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS13570
gene id: 1182568:SU48_RS13570
uniprot id: A0A172TC63
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06415
gene id: 1182568:SU48_RS06415
uniprot id: A0A172T8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS05765
gene id: 1182568:SU48_RS05765
uniprot id: A0A172TCW5
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS07095
gene id: 1182568:SU48_RS07095
uniprot id: A0A172T9T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1182568:SU48 RS03110
gene id: 1182568:SU48_RS03110
uniprot id: A0A172T7X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1182568:SU48 RS01715
gene id: 1182568:SU48_RS01715
uniprot id: A0A172T6V7
names: Similarity
messages: Belongs to the GSP E family.

1182568:SU48 RS04540
gene id: 1182568:SU48_RS04540
uniprot id: A0A172T805
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1182568:SU48 RS11130
gene id: 1182568:SU48_RS11130
uniprot id: A0A172TB00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1182568:SU48 RS11520
gene id: 1182568:SU48_RS11520
uniprot id: A0A172TBE7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1182568:SU48 RS12840
gene id: 1182568:SU48_RS12840
uniprot id: A0A172TC11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1182568:SU48 RS06335
gene id: 1182568:SU48_RS06335
uniprot id: A0A172T8U9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1182568:SU48 RS10720
gene id: 1182568:SU48_RS10720
uniprot id: A0A172TB70
names: Similarity
messages: Belongs to the DinB family.

1182568:SU48 RS02590
gene id: 1182568:SU48_RS02590
uniprot id: A0A172T764
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1182568:SU48 RS11145
gene id: 1182568:SU48_RS11145
uniprot id: A0A172TB34
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1182568:SU48 RS11400
gene id: 1182568:SU48_RS11400
uniprot id: A0A172TB84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1182568:SU48 RS00945
gene id: 1182568:SU48_RS00945
uniprot id: A0A172T6X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1182568:SU48 RS04880
gene id: 1182568:SU48_RS04880
uniprot id: A0A172T8A2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1182568:SU48 RS05640
gene id: 1182568:SU48_RS05640
uniprot id: A0A172T8R5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1182568:SU48 RS11420
gene id: 1182568:SU48_RS11420
uniprot id: A0A172TBG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1182568:SU48 RS11380
gene id: 1182568:SU48_RS11380
uniprot id: A0A172TBG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1182568:SU48 RS03530
gene id: 1182568:SU48_RS03530
uniprot id: A0A172T7I8
names: Subcellular Location Annotation
messages: Cytoplasm

1182568:SU48 RS07415
gene id: 1182568:SU48_RS07415
uniprot id: A0A172T9E4
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1182568:SU48 RS07255
gene id: 1182568:SU48_RS07255
uniprot id: A0A172T9A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1182568:SU48 RS01775
gene id: 1182568:SU48_RS01775
uniprot id: A0A172TD30
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1182568:SU48 RS12750
gene id: 1182568:SU48_RS12750
uniprot id: A0A172TC04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1182568:SU48 RS03500
gene id: 1182568:SU48_RS03500
uniprot id: A0A172T843
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1182568:SU48 RS02415
gene id: 1182568:SU48_RS02415
uniprot id: A0A172T7A4
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1182568:SU48 RS04005
gene id: 1182568:SU48_RS04005
uniprot id: A0A172T7R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1182568:SU48 RS01165
gene id: 1182568:SU48_RS01165
uniprot id: A0A172T6E7
names: Similarity
messages: Belongs to the peptidase S33 family.

1182568:SU48 RS05530
gene id: 1182568:SU48_RS05530
uniprot id: A0A172T8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1182568:SU48 RS03080
gene id: 1182568:SU48_RS03080
uniprot id: A0A172T7A9
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS04340
gene id: 1182568:SU48_RS04340
uniprot id: A0A172T7V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS13445
gene id: 1182568:SU48_RS13445
uniprot id: A0A172TC46
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS09855
gene id: 1182568:SU48_RS09855
uniprot id: A0A172TAR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1182568:SU48 RS09870
gene id: 1182568:SU48_RS09870
uniprot id: A0A172TAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1182568:SU48 RS08075
gene id: 1182568:SU48_RS08075
uniprot id: A0A172T9N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1182568:SU48 RS02050
gene id: 1182568:SU48_RS02050
uniprot id: A0A172T6T6
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1182568:SU48 RS07205
gene id: 1182568:SU48_RS07205
uniprot id: A0A172T9F6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1182568:SU48 RS00795
gene id: 1182568:SU48_RS00795
uniprot id: A0A172T679
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.

1182568:SU48 RS09675
gene id: 1182568:SU48_RS09675
uniprot id: A0A172TB15
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS09755
gene id: 1182568:SU48_RS09755
uniprot id: A0A172TAF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1182568:SU48 RS11060
gene id: 1182568:SU48_RS11060
uniprot id: A0A172TAZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1182568:SU48 RS02885
gene id: 1182568:SU48_RS02885
uniprot id: A0A172T7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1182568:SU48 RS13315
gene id: 1182568:SU48_RS13315
uniprot id: A0A172TC22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1182568:SU48 RS12590
gene id: 1182568:SU48_RS12590
uniprot id: A0A172TBP8
names: Similarity
messages: Belongs to the DinB family.

1182568:SU48 RS01530
gene id: 1182568:SU48_RS01530
uniprot id: A0A172T6K5
names: Similarity
messages: Belongs to the XseB family.

1182568:SU48 RS04590
gene id: 1182568:SU48_RS04590
uniprot id: A0A172T892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS11530
gene id: 1182568:SU48_RS11530
uniprot id: A0A172TBI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1182568:SU48 RS09440
gene id: 1182568:SU48_RS09440
uniprot id: A0A172TAL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1182568:SU48 RS10025
gene id: 1182568:SU48_RS10025
uniprot id: A0A172TAN7
names: Similarity
messages: Belongs to the ycf81 family.

1182568:SU48 RS10185
gene id: 1182568:SU48_RS10185
uniprot id: A0A172TB89
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1182568:SU48 RS12725
gene id: 1182568:SU48_RS12725
uniprot id: A0A172TBW8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1182568:SU48 RS07955
gene id: 1182568:SU48_RS07955
uniprot id: A0A172T9T8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1182568:SU48 RS07580
gene id: 1182568:SU48_RS07580
uniprot id: A0A172T9F5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1182568:SU48 RS12460
gene id: 1182568:SU48_RS12460
uniprot id: A0A172TBV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1182568:SU48 RS12370
gene id: 1182568:SU48_RS12370
uniprot id: A0A172TBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS01870
gene id: 1182568:SU48_RS01870
uniprot id: A0A172T6X5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS07335
gene id: 1182568:SU48_RS07335
uniprot id: A0A172T9J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1182568:SU48 RS10695
gene id: 1182568:SU48_RS10695
uniprot id: A0A172TBI6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1182568:SU48 RS05935
gene id: 1182568:SU48_RS05935
uniprot id: A0A172T8W6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1182568:SU48 RS07885
gene id: 1182568:SU48_RS07885
uniprot id: A0A172T9R6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1182568:SU48 RS02020
gene id: 1182568:SU48_RS02020
uniprot id: A0A172TCF8
names: Similarity
messages: Belongs to the P(II) protein family.

1182568:SU48 RS00845
gene id: 1182568:SU48_RS00845
uniprot id: A0A172T6H9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1182568:SU48 RS05815
gene id: 1182568:SU48_RS05815
uniprot id: A0A172T978
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS00340
gene id: 1182568:SU48_RS00340
uniprot id: A0A172T684
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1182568:SU48 RS03885
gene id: 1182568:SU48_RS03885
uniprot id: A0A172T7T9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1182568:SU48 RS06815
gene id: 1182568:SU48_RS06815
uniprot id: A0A172T936
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06690
gene id: 1182568:SU48_RS06690
uniprot id: A0A172T8Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS00885
gene id: 1182568:SU48_RS00885
uniprot id: A0A172T6W2
names: Similarity
messages: Belongs to the CinA family.

1182568:SU48 RS03730
gene id: 1182568:SU48_RS03730
uniprot id: A0A172T7M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1182568:SU48 RS00805
gene id: 1182568:SU48_RS00805
uniprot id: A0A172T6D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1182568:SU48 RS12045
gene id: 1182568:SU48_RS12045
uniprot id: A0A172TBE8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS08050
gene id: 1182568:SU48_RS08050
uniprot id: A0A172T9N9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1182568:SU48 RS08800
gene id: 1182568:SU48_RS08800
uniprot id: A0A172TAM8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS09450
gene id: 1182568:SU48_RS09450
uniprot id: A0A172TAC6
names: Cofactor
messages: Binds 1 FAD per subunit.

1182568:SU48 RS10160
gene id: 1182568:SU48_RS10160
uniprot id: A0A172TAQ7
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS06820
gene id: 1182568:SU48_RS06820
uniprot id: A0A172TCV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1182568:SU48 RS07760
gene id: 1182568:SU48_RS07760
uniprot id: A0A172T9P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1182568:SU48 RS00035
gene id: 1182568:SU48_RS00035
uniprot id: A0A172T628
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1182568:SU48 RS05150
gene id: 1182568:SU48_RS05150
uniprot id: A0A172T896
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1182568:SU48 RS05370
gene id: 1182568:SU48_RS05370
uniprot id: A0A172T913
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS10675
gene id: 1182568:SU48_RS10675
uniprot id: A0A172TAV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.
messages: In the C-terminal section; belongs to the urease beta subunit family.
messages: In the N-terminal section; belongs to the urease gamma subunit family.

1182568:SU48 RS03710
gene id: 1182568:SU48_RS03710
uniprot id: A0A172T7W1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1182568:SU48 RS07360
gene id: 1182568:SU48_RS07360
uniprot id: A0A172T9E3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1182568:SU48 RS07690
gene id: 1182568:SU48_RS07690
uniprot id: A0A172T9N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1182568:SU48 RS09300
gene id: 1182568:SU48_RS09300
uniprot id: A0A172TAB4
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1182568:SU48 RS02305
gene id: 1182568:SU48_RS02305
uniprot id: A0A172T6X9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1182568:SU48 RS10745
gene id: 1182568:SU48_RS10745
uniprot id: A0A172TB33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1182568:SU48 RS10200
gene id: 1182568:SU48_RS10200
uniprot id: A0A172TAX3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1182568:SU48 RS05395
gene id: 1182568:SU48_RS05395
uniprot id: A0A172T8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS05120
gene id: 1182568:SU48_RS05120
uniprot id: A0A172T8X3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1182568:SU48 RS09930
gene id: 1182568:SU48_RS09930
uniprot id: A0A172TAT7
names: Similarity
messages: Belongs to the malate synthase family.

1182568:SU48 RS12270
gene id: 1182568:SU48_RS12270
uniprot id: A0A172TBK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS11090
gene id: 1182568:SU48_RS11090
uniprot id: A0A172TB31
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1182568:SU48 RS12605
gene id: 1182568:SU48_RS12605
uniprot id: A0A172TBU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1182568:SU48 RS07020
gene id: 1182568:SU48_RS07020
uniprot id: A0A172T985
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1182568:SU48 RS08045
gene id: 1182568:SU48_RS08045
uniprot id: A0A172T9N7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1182568:SU48 RS00005
gene id: 1182568:SU48_RS00005
uniprot id: A0A172TC70
names: Similarity
messages: Belongs to the GSP E family.

1182568:SU48 RS00780
gene id: 1182568:SU48_RS00780
uniprot id: A0A172T668
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1182568:SU48 RS08565
gene id: 1182568:SU48_RS08565
uniprot id: A0A172TA33
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1182568:SU48 RS12040
gene id: 1182568:SU48_RS12040
uniprot id: A0A172TBR6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1182568:SU48 RS11735
gene id: 1182568:SU48_RS11735
uniprot id: A0A172TBJ2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1182568:SU48 RS08825
gene id: 1182568:SU48_RS08825
uniprot id: A0A172TA08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1182568:SU48 RS09905
gene id: 1182568:SU48_RS09905
uniprot id: A0A172TAL7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1182568:SU48 RS11910
gene id: 1182568:SU48_RS11910
uniprot id: A0A172TBJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1182568:SU48 RS05590
gene id: 1182568:SU48_RS05590
uniprot id: A0A172TCY4
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS02530
gene id: 1182568:SU48_RS02530
uniprot id: A0A172TCK4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1182568:SU48 RS12315
gene id: 1182568:SU48_RS12315
uniprot id: A0A172TBT3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1182568:SU48 RS04895
gene id: 1182568:SU48_RS04895
uniprot id: A0A172T8E2
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1182568:SU48 RS08520
gene id: 1182568:SU48_RS08520
uniprot id: A0A172T9W3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1182568:SU48 RS11600
gene id: 1182568:SU48_RS11600
uniprot id: A0A172TBJ7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1182568:SU48 RS13485
gene id: 1182568:SU48_RS13485
uniprot id: A0A172TC19
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1182568:SU48 RS11455
gene id: 1182568:SU48_RS11455
uniprot id: A0A172TBC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1182568:SU48 RS08255
gene id: 1182568:SU48_RS08255
uniprot id: A0A172T9U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS12745
gene id: 1182568:SU48_RS12745
uniprot id: A0A172TBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1182568:SU48 RS04930
gene id: 1182568:SU48_RS04930
uniprot id: A0A172T866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1182568:SU48 RS06440
gene id: 1182568:SU48_RS06440
uniprot id: A0A172T946
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1182568:SU48 RS00915
gene id: 1182568:SU48_RS00915
uniprot id: A0A172T6I2
names: Similarity
messages: Belongs to the TrpF family.

1182568:SU48 RS13085
gene id: 1182568:SU48_RS13085
uniprot id: A0A172TDA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1182568:SU48 RS09325
gene id: 1182568:SU48_RS09325
uniprot id: A0A172TAI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1182568:SU48 RS09375
gene id: 1182568:SU48_RS09375
uniprot id: A0A172TAI0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1182568:SU48 RS12400
gene id: 1182568:SU48_RS12400
uniprot id: A0A172TBT8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1182568:SU48 RS00550
gene id: 1182568:SU48_RS00550
uniprot id: A0A172T691
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1182568:SU48 RS05095
gene id: 1182568:SU48_RS05095
uniprot id: A0A172T880
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS02060
gene id: 1182568:SU48_RS02060
uniprot id: A0A172T6Y0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1182568:SU48 RS05015
gene id: 1182568:SU48_RS05015
uniprot id: A0A172T8G2
names: Similarity
messages: Belongs to the leucine-binding protein family.

1182568:SU48 RS09830
gene id: 1182568:SU48_RS09830
uniprot id: A0A172TAI3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1182568:SU48 RS07110
gene id: 1182568:SU48_RS07110
uniprot id: A0A172T9F9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1182568:SU48 RS13290
gene id: 1182568:SU48_RS13290
uniprot id: A0A172TCB3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1182568:SU48 RS02290
gene id: 1182568:SU48_RS02290
uniprot id: A0A172T6W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1182568:SU48 RS08510
gene id: 1182568:SU48_RS08510
uniprot id: A0A172TAH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1182568:SU48 RS04780
gene id: 1182568:SU48_RS04780
uniprot id: A0A172T828
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

1182568:SU48 RS00710
gene id: 1182568:SU48_RS00710
uniprot id: A0A172TCH9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1182568:SU48 RS11895
gene id: 1182568:SU48_RS11895
uniprot id: A0A172TBF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS04935
gene id: 1182568:SU48_RS04935
uniprot id: A0A172T887
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS09190
gene id: 1182568:SU48_RS09190
uniprot id: A0A172TAD4
names: Similarity
messages: Belongs to the GARS family.

1182568:SU48 RS13640
gene id: 1182568:SU48_RS13640
uniprot id: A0A172TC89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1182568:SU48 RS06565
gene id: 1182568:SU48_RS06565
uniprot id: A0A172T8X9
names: Cofactor
messages: Can also use Mn(2+) ion.

1182568:SU48 RS03590
gene id: 1182568:SU48_RS03590
uniprot id: A0A172T7Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1182568:SU48 RS09690
gene id: 1182568:SU48_RS09690
uniprot id: A0A172TAP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1182568:SU48 RS02065
gene id: 1182568:SU48_RS02065
uniprot id: A0A172T707
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1182568:SU48 RS06965
gene id: 1182568:SU48_RS06965
uniprot id: A0A172T980
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1182568:SU48 RS11670
gene id: 1182568:SU48_RS11670
uniprot id: A0A172TBK5
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

1182568:SU48 RS04025
gene id: 1182568:SU48_RS04025
uniprot id: A0A172T8D1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS07010
gene id: 1182568:SU48_RS07010
uniprot id: A0A172T955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1182568:SU48 RS07125
gene id: 1182568:SU48_RS07125
uniprot id: A0A172T975
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1182568:SU48 RS04645
gene id: 1182568:SU48_RS04645
uniprot id: A0A172T8A4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1182568:SU48 RS08625
gene id: 1182568:SU48_RS08625
uniprot id: A0A172TA42
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1182568:SU48 RS00255
gene id: 1182568:SU48_RS00255
uniprot id: A0A172T650
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1182568:SU48 RS07155
gene id: 1182568:SU48_RS07155
uniprot id: A0A172T9U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1182568:SU48 RS00360
gene id: 1182568:SU48_RS00360
uniprot id: A0A172T611
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1182568:SU48 RS07490
gene id: 1182568:SU48_RS07490
uniprot id: A0A172T9K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS04840
gene id: 1182568:SU48_RS04840
uniprot id: A0A172T8D3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1182568:SU48 RS01260
gene id: 1182568:SU48_RS01260
uniprot id: A0A172T6N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS11570
gene id: 1182568:SU48_RS11570
uniprot id: A0A172TB91
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1182568:SU48 RS03540
gene id: 1182568:SU48_RS03540
uniprot id: A0A172T7M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1182568:SU48 RS13755
gene id: 1182568:SU48_RS13755
uniprot id: A0A172TC97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1182568:SU48 RS09800
gene id: 1182568:SU48_RS09800
uniprot id: A0A172TAQ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1182568:SU48 RS02890
gene id: 1182568:SU48_RS02890
uniprot id: A0A172T7F7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1182568:SU48 RS11300
gene id: 1182568:SU48_RS11300
uniprot id: A0A172TBS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1182568:SU48 RS01295
gene id: 1182568:SU48_RS01295
uniprot id: A0A172T6L5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1182568:SU48 RS12630
gene id: 1182568:SU48_RS12630
uniprot id: A0A172TBN8
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS03350
gene id: 1182568:SU48_RS03350
uniprot id: A0A172T7Q4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1182568:SU48 RS03510
gene id: 1182568:SU48_RS03510
uniprot id: A0A172T7H0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1182568:SU48 RS10875
gene id: 1182568:SU48_RS10875
uniprot id: A0A172TBM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1182568:SU48 RS06705
gene id: 1182568:SU48_RS06705
uniprot id: A0A172T940
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1182568:SU48 RS00355
gene id: 1182568:SU48_RS00355
uniprot id: A0A172T697
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1182568:SU48 RS11170
gene id: 1182568:SU48_RS11170
uniprot id: A0A172TB85
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS12085
gene id: 1182568:SU48_RS12085
uniprot id: A0A172TBG8
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS05160
gene id: 1182568:SU48_RS05160
uniprot id: A0A172TCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS00565
gene id: 1182568:SU48_RS00565
uniprot id: A0A172T6B3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1182568:SU48 RS00095
gene id: 1182568:SU48_RS00095
uniprot id: A0A172T6I0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1182568:SU48 RS05000
gene id: 1182568:SU48_RS05000
uniprot id: A0A172T8F6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1182568:SU48 RS05905
gene id: 1182568:SU48_RS05905
uniprot id: A0A172T8M7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1182568:SU48 RS03645
gene id: 1182568:SU48_RS03645
uniprot id: A0A172TCW0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA.

1182568:SU48 RS11085
gene id: 1182568:SU48_RS11085
uniprot id: A0A172TB12
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-67 and Arg-70) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1182568:SU48 RS02980
gene id: 1182568:SU48_RS02980
uniprot id: A0A172T7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1182568:SU48 RS08665
gene id: 1182568:SU48_RS08665
uniprot id: A0A172T9Z8
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

1182568:SU48 RS06680
gene id: 1182568:SU48_RS06680
uniprot id: A0A172T987
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS08980
gene id: 1182568:SU48_RS08980
uniprot id: A0A172TA61
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1182568:SU48 RS13675
gene id: 1182568:SU48_RS13675
uniprot id: A0A172TCH5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1182568:SU48 RS10950
gene id: 1182568:SU48_RS10950
uniprot id: A0A172TB47
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS05920
gene id: 1182568:SU48_RS05920
uniprot id: A0A172T8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS09335
gene id: 1182568:SU48_RS09335
uniprot id: A0A172TA93
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1182568:SU48 RS02095
gene id: 1182568:SU48_RS02095
uniprot id: A0A172T6U7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

1182568:SU48 RS04600
gene id: 1182568:SU48_RS04600
uniprot id: A0A172T814
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1182568:SU48 RS11540
gene id: 1182568:SU48_RS11540
uniprot id: A0A172TBG3
names: Similarity
messages: Belongs to the fabD family.

1182568:SU48 RS12685
gene id: 1182568:SU48_RS12685
uniprot id: A0A172TC14
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1182568:SU48 RS12135
gene id: 1182568:SU48_RS12135
uniprot id: A0A172TBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1182568:SU48 RS02565
gene id: 1182568:SU48_RS02565
uniprot id: A0A172T715
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS13655
gene id: 1182568:SU48_RS13655
uniprot id: A0A172TDB4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1182568:SU48 RS00995
gene id: 1182568:SU48_RS00995
uniprot id: A0A172T6I6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1182568:SU48 RS10480
gene id: 1182568:SU48_RS10480
uniprot id: A0A172TAT4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1182568:SU48 RS02225
gene id: 1182568:SU48_RS02225
uniprot id: A0A172T7H6
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS09460
gene id: 1182568:SU48_RS09460
uniprot id: A0A172TAE1
names: Similarity
messages: Belongs to the peptidase S8 family.

1182568:SU48 RS11395
gene id: 1182568:SU48_RS11395
uniprot id: A0A172TB62
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1182568:SU48 RS11725
gene id: 1182568:SU48_RS11725
uniprot id: A0A172TBL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1182568:SU48 RS06800
gene id: 1182568:SU48_RS06800
uniprot id: A0A172T9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1182568:SU48 RS08900
gene id: 1182568:SU48_RS08900
uniprot id: A0A172TAC0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1182568:SU48 RS11700
gene id: 1182568:SU48_RS11700
uniprot id: A0A172TBD1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1182568:SU48 RS06640
gene id: 1182568:SU48_RS06640
uniprot id: A0A172T908
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1182568:SU48 RS08560
gene id: 1182568:SU48_RS08560
uniprot id: A0A172T9Y8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1182568:SU48 RS00440
gene id: 1182568:SU48_RS00440
uniprot id: A0A172TCK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1182568:SU48 RS03515
gene id: 1182568:SU48_RS03515
uniprot id: A0A172T7S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1182568:SU48 RS00535
gene id: 1182568:SU48_RS00535
uniprot id: A0A172T6C2
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1182568:SU48 RS11810
gene id: 1182568:SU48_RS11810
uniprot id: A0A172TBN9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1182568:SU48 RS08715
gene id: 1182568:SU48_RS08715
uniprot id: A0A172TA91
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1182568:SU48 RS12260
gene id: 1182568:SU48_RS12260
uniprot id: A0A172TBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS02405
gene id: 1182568:SU48_RS02405
uniprot id: A0A172T6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1182568:SU48 RS09175
gene id: 1182568:SU48_RS09175
uniprot id: A0A172TA75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1182568:SU48 RS09320
gene id: 1182568:SU48_RS09320
uniprot id: A0A172TA90
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1182568:SU48 RS02805
gene id: 1182568:SU48_RS02805
uniprot id: A0A172T7S3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1182568:SU48 RS02115
gene id: 1182568:SU48_RS02115
uniprot id: A0A172T7F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1182568:SU48 RS01130
gene id: 1182568:SU48_RS01130
uniprot id: A0A172T6L6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06950
gene id: 1182568:SU48_RS06950
uniprot id: A0A172T945
names: Similarity
messages: Belongs to the PspA/IM30 family.

1182568:SU48 RS05020
gene id: 1182568:SU48_RS05020
uniprot id: A0A172T871
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS11475
gene id: 1182568:SU48_RS11475
uniprot id: A0A172TBH3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1182568:SU48 RS04530
gene id: 1182568:SU48_RS04530
uniprot id: A0A172T891
names: Similarity
messages: Belongs to the peptidase S8 family.

1182568:SU48 RS06890
gene id: 1182568:SU48_RS06890
uniprot id: A0A172TDG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1182568:SU48 RS04365
gene id: 1182568:SU48_RS04365
uniprot id: A0A172T7X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1182568:SU48 RS04250
gene id: 1182568:SU48_RS04250
uniprot id: A0A172T834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1182568:SU48 RS06275
gene id: 1182568:SU48_RS06275
uniprot id: A0A172T8U8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1182568:SU48 RS03525
gene id: 1182568:SU48_RS03525
uniprot id: A0A172T7J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1182568:SU48 RS03200
gene id: 1182568:SU48_RS03200
uniprot id: A0A172T7H7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1182568:SU48 RS05660
gene id: 1182568:SU48_RS05660
uniprot id: A0A172T8K5
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1182568:SU48 RS06580
gene id: 1182568:SU48_RS06580
uniprot id: A0A172T922
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS08935
gene id: 1182568:SU48_RS08935
uniprot id: A0A172TAB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1182568:SU48 RS03495
gene id: 1182568:SU48_RS03495
uniprot id: A0A172T7R6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1182568:SU48 RS12815
gene id: 1182568:SU48_RS12815
uniprot id: A0A172TC50
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1182568:SU48 RS04765
gene id: 1182568:SU48_RS04765
uniprot id: A0A172T8C0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS07150
gene id: 1182568:SU48_RS07150
uniprot id: A0A172T9E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1182568:SU48 RS00635
gene id: 1182568:SU48_RS00635
uniprot id: A0A172T649
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS05950
gene id: 1182568:SU48_RS05950
uniprot id: A0A172T8W4
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS12705
gene id: 1182568:SU48_RS12705
uniprot id: A0A172TBS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1182568:SU48 RS05100
gene id: 1182568:SU48_RS05100
uniprot id: A0A172T894
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1182568:SU48 RS04915
gene id: 1182568:SU48_RS04915
uniprot id: A0A172T8E3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1182568:SU48 RS10330
gene id: 1182568:SU48_RS10330
uniprot id: A0A172TAY8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1182568:SU48 RS04815
gene id: 1182568:SU48_RS04815
uniprot id: A0A172T845
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1182568:SU48 RS05190
gene id: 1182568:SU48_RS05190
uniprot id: A0A172T8Y2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1182568:SU48 RS03605
gene id: 1182568:SU48_RS03605
uniprot id: A0A172T872
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1182568:SU48 RS12775
gene id: 1182568:SU48_RS12775
uniprot id: A0A172TBV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06805
gene id: 1182568:SU48_RS06805
uniprot id: A0A172T915
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1182568:SU48 RS06575
gene id: 1182568:SU48_RS06575
uniprot id: A0A172T8Z9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1182568:SU48 RS09085
gene id: 1182568:SU48_RS09085
uniprot id: A0A172TAF5
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1182568:SU48 RS05230
gene id: 1182568:SU48_RS05230
uniprot id: A0A172T8F4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1182568:SU48 RS02695
gene id: 1182568:SU48_RS02695
uniprot id: A0A172T7C1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1182568:SU48 RS11035
gene id: 1182568:SU48_RS11035
uniprot id: A0A172TB55
names: Similarity
messages: Belongs to the peptidase S1C family.

1182568:SU48 RS09405
gene id: 1182568:SU48_RS09405
uniprot id: A0A172TAB5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1182568:SU48 RS11445
gene id: 1182568:SU48_RS11445
uniprot id: A0A172TB73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1182568:SU48 RS06935
gene id: 1182568:SU48_RS06935
uniprot id: A0A172T938
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1182568:SU48 RS02040
gene id: 1182568:SU48_RS02040
uniprot id: A0A172T709
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS11265
gene id: 1182568:SU48_RS11265
uniprot id: A0A172TBB2
names: Similarity
messages: Belongs to the thioredoxin family.

1182568:SU48 RS02925
gene id: 1182568:SU48_RS02925
uniprot id: A0A172T7H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1182568:SU48 RS11805
gene id: 1182568:SU48_RS11805
uniprot id: A0A172TBK1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1182568:SU48 RS12030
gene id: 1182568:SU48_RS12030
uniprot id: A0A172TBM4
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1182568:SU48 RS12575
gene id: 1182568:SU48_RS12575
uniprot id: A0A172TBX6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1182568:SU48 RS06035
gene id: 1182568:SU48_RS06035
uniprot id: A0A172T8Q9
names: Similarity
messages: Belongs to the BshC family.

1182568:SU48 RS11250
gene id: 1182568:SU48_RS11250
uniprot id: A0A172TBD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1182568:SU48 RS05835
gene id: 1182568:SU48_RS05835
uniprot id: A0A172T8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS10065
gene id: 1182568:SU48_RS10065
uniprot id: A0A172TD48
names: Similarity
messages: Belongs to the acylphosphatase family.

1182568:SU48 RS13415
gene id: 1182568:SU48_RS13415
uniprot id: A0A172TDB7
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS09645
gene id: 1182568:SU48_RS09645
uniprot id: A0A172TAF6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1182568:SU48 RS03650
gene id: 1182568:SU48_RS03650
uniprot id: A0A172T7U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1182568:SU48 RS00250
gene id: 1182568:SU48_RS00250
uniprot id: A0A172T645
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1182568:SU48 RS07935
gene id: 1182568:SU48_RS07935
uniprot id: A0A172T9L9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1182568:SU48 RS01845
gene id: 1182568:SU48_RS01845
uniprot id: A0A172T6Y1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1182568:SU48 RS06445
gene id: 1182568:SU48_RS06445
uniprot id: A0A172T953
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1182568:SU48 RS13790
gene id: 1182568:SU48_RS13790
uniprot id: A0A172TCY0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1182568:SU48 RS11610
gene id: 1182568:SU48_RS11610
uniprot id: A0A172TBH2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS02045
gene id: 1182568:SU48_RS02045
uniprot id: A0A172T6T1
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1182568:SU48 RS13525
gene id: 1182568:SU48_RS13525
uniprot id: A0A172TCT6
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS11165
gene id: 1182568:SU48_RS11165
uniprot id: A0A172TB74
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1182568:SU48 RS01520
gene id: 1182568:SU48_RS01520
uniprot id: A0A172T6U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1182568:SU48 RS11845
gene id: 1182568:SU48_RS11845
uniprot id: A0A172TBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS05105
gene id: 1182568:SU48_RS05105
uniprot id: A0A172T8B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1182568:SU48 RS07245
gene id: 1182568:SU48_RS07245
uniprot id: A0A172T989
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06155
gene id: 1182568:SU48_RS06155
uniprot id: A0A172T8S9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS07035
gene id: 1182568:SU48_RS07035
uniprot id: A0A172T9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1182568:SU48 RS03680
gene id: 1182568:SU48_RS03680
uniprot id: A0A172T7U6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1182568:SU48 RS02105
gene id: 1182568:SU48_RS02105
uniprot id: A0A172T6Y9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1182568:SU48 RS00605
gene id: 1182568:SU48_RS00605
uniprot id: A0A172T6A1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS11285
gene id: 1182568:SU48_RS11285
uniprot id: A0A172TB63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1182568:SU48 RS05565
gene id: 1182568:SU48_RS05565
uniprot id: A0A172T8Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1182568:SU48 RS03490
gene id: 1182568:SU48_RS03490
uniprot id: A0A172T7L9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1182568:SU48 RS08235
gene id: 1182568:SU48_RS08235
uniprot id: A0A172TA10
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1182568:SU48 RS09275
gene id: 1182568:SU48_RS09275
uniprot id: A0A172TAI6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

1182568:SU48 RS08500
gene id: 1182568:SU48_RS08500
uniprot id: A0A172TA23
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS07045
gene id: 1182568:SU48_RS07045
uniprot id: A0A172T963
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1182568:SU48 RS06895
gene id: 1182568:SU48_RS06895
uniprot id: A0A172T9A5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1182568:SU48 RS08905
gene id: 1182568:SU48_RS08905
uniprot id: A0A172TA15
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1182568:SU48 RS09015
gene id: 1182568:SU48_RS09015
uniprot id: A0A172TAD2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1182568:SU48 RS05595
gene id: 1182568:SU48_RS05595
uniprot id: A0A172T8I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1182568:SU48 RS08915
gene id: 1182568:SU48_RS08915
uniprot id: A0A172TA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS08615
gene id: 1182568:SU48_RS08615
uniprot id: A0A172T9Y7
names: Subcellular Location Annotation
messages: Cytoplasm

1182568:SU48 RS02100
gene id: 1182568:SU48_RS02100
uniprot id: A0A172T6Y8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1182568:SU48 RS05650
gene id: 1182568:SU48_RS05650
uniprot id: A0A172T8I3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1182568:SU48 RS10205
gene id: 1182568:SU48_RS10205
uniprot id: A0A172TAY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1182568:SU48 RS06450
gene id: 1182568:SU48_RS06450
uniprot id: A0A172TCR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1182568:SU48 RS07940
gene id: 1182568:SU48_RS07940
uniprot id: A0A172T9N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1182568:SU48 RS13170
gene id: 1182568:SU48_RS13170
uniprot id: A0A172TC77
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1182568:SU48 RS11815
gene id: 1182568:SU48_RS11815
uniprot id: A0A172TBE1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1182568:SU48 RS12735
gene id: 1182568:SU48_RS12735
uniprot id: A0A172TCF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS01180
gene id: 1182568:SU48_RS01180
uniprot id: A0A172T6I8
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS04680
gene id: 1182568:SU48_RS04680
uniprot id: A0A172T8Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1182568:SU48 RS03795
gene id: 1182568:SU48_RS03795
uniprot id: A0A172T7W9
names: Similarity
messages: Belongs to the FUN14 family.

1182568:SU48 RS04865
gene id: 1182568:SU48_RS04865
uniprot id: A0A172T849
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1182568:SU48 RS06150
gene id: 1182568:SU48_RS06150
uniprot id: A0A172T8R8
names: Similarity
messages: Belongs to the ComB family.

1182568:SU48 RS04925
gene id: 1182568:SU48_RS04925
uniprot id: A0A172TCU6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1182568:SU48 RS02540
gene id: 1182568:SU48_RS02540
uniprot id: A0A172T7M0
names: Similarity
messages: Belongs to the SCO1/2 family.

1182568:SU48 RS02255
gene id: 1182568:SU48_RS02255
uniprot id: A0A172T6X7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1182568:SU48 RS06200
gene id: 1182568:SU48_RS06200
uniprot id: A0A172T907
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

1182568:SU48 RS12110
gene id: 1182568:SU48_RS12110
uniprot id: A0A172TC52
names: Similarity
messages: Belongs to the UPF0047 family.

1182568:SU48 RS00720
gene id: 1182568:SU48_RS00720
uniprot id: A0A172T6F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1182568:SU48 RS01265
gene id: 1182568:SU48_RS01265
uniprot id: A0A172T6E2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS01445
gene id: 1182568:SU48_RS01445
uniprot id: A0A172T6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS00205
gene id: 1182568:SU48_RS00205
uniprot id: A0A172T657
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06905
gene id: 1182568:SU48_RS06905
uniprot id: A0A172T9Q8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1182568:SU48 RS11580
gene id: 1182568:SU48_RS11580
uniprot id: A0A172TBE6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1182568:SU48 RS03130
gene id: 1182568:SU48_RS03130
uniprot id: A0A172T7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1182568:SU48 RS13065
gene id: 1182568:SU48_RS13065
uniprot id: A0A172TBY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1182568:SU48 RS11935
gene id: 1182568:SU48_RS11935
uniprot id: A0A172TBM1
names: Similarity
messages: Belongs to the FBPase class 2 family.

1182568:SU48 RS02915
gene id: 1182568:SU48_RS02915
uniprot id: A0A172T7G0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1182568:SU48 RS02365
gene id: 1182568:SU48_RS02365
uniprot id: A0A172TCQ4
names: Similarity
messages: Belongs to the universal stress protein A family.

1182568:SU48 RS09860
gene id: 1182568:SU48_RS09860
uniprot id: A0A172TAH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1182568:SU48 RS04985
gene id: 1182568:SU48_RS04985
uniprot id: A0A172T873
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS05265
gene id: 1182568:SU48_RS05265
uniprot id: A0A172T8C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1182568:SU48 RS08920
gene id: 1182568:SU48_RS08920
uniprot id: A0A172TA50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS10540
gene id: 1182568:SU48_RS10540
uniprot id: A0A172TAT8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1182568:SU48 RS07430
gene id: 1182568:SU48_RS07430
uniprot id: A0A172TA00
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1182568:SU48 RS04820
gene id: 1182568:SU48_RS04820
uniprot id: A0A172T882
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1182568:SU48 RS08105
gene id: 1182568:SU48_RS08105
uniprot id: A0A172T9R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1182568:SU48 RS09010
gene id: 1182568:SU48_RS09010
uniprot id: A0A172TA44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1182568:SU48 RS13015
gene id: 1182568:SU48_RS13015
uniprot id: A0A172TBZ0
names: Similarity
messages: Belongs to the peptidase S9C family.

1182568:SU48 RS01420
gene id: 1182568:SU48_RS01420
uniprot id: A0A172T6Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS10770
gene id: 1182568:SU48_RS10770
uniprot id: A0A172TDR8
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS12585
gene id: 1182568:SU48_RS12585
uniprot id: A0A172TBQ4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1182568:SU48 RS08850
gene id: 1182568:SU48_RS08850
uniprot id: A0A172TA39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1182568:SU48 RS09165
gene id: 1182568:SU48_RS09165
uniprot id: A0A172TD24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS10030
gene id: 1182568:SU48_RS10030
uniprot id: A0A172TAS2
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS06635
gene id: 1182568:SU48_RS06635
uniprot id: A0A172T8Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1182568:SU48 RS05570
gene id: 1182568:SU48_RS05570
uniprot id: A0A172T8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1182568:SU48 RS04065
gene id: 1182568:SU48_RS04065
uniprot id: A0A172TCR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS02295
gene id: 1182568:SU48_RS02295
uniprot id: A0A172T783
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1182568:SU48 RS09965
gene id: 1182568:SU48_RS09965
uniprot id: A0A172TAK0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS13760
gene id: 1182568:SU48_RS13760
uniprot id: A0A172TC92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1182568:SU48 RS01375
gene id: 1182568:SU48_RS01375
uniprot id: A0A172T6H0
names: Similarity
messages: Belongs to the peptidase S58 family.

1182568:SU48 RS02665
gene id: 1182568:SU48_RS02665
uniprot id: A0A172T7E1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1182568:SU48 RS09935
gene id: 1182568:SU48_RS09935
uniprot id: A0A172TAU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1182568:SU48 RS06920
gene id: 1182568:SU48_RS06920
uniprot id: A0A172T9D0
names: Similarity
messages: Belongs to the GSP E family.

1182568:SU48 RS07870
gene id: 1182568:SU48_RS07870
uniprot id: A0A172T9K4
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1182568:SU48 RS04875
gene id: 1182568:SU48_RS04875
uniprot id: A0A172T886
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1182568:SU48 RS12250
gene id: 1182568:SU48_RS12250
uniprot id: A0A172TDF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1182568:SU48 RS08100
gene id: 1182568:SU48_RS08100
uniprot id: A0A172T9P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1182568:SU48 RS09885
gene id: 1182568:SU48_RS09885
uniprot id: A0A172TAI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1182568:SU48 RS10570
gene id: 1182568:SU48_RS10570
uniprot id: A0A172TB30
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1182568:SU48 RS00905
gene id: 1182568:SU48_RS00905
uniprot id: A0A172TCD2
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS08690
gene id: 1182568:SU48_RS08690
uniprot id: A0A172TA71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1182568:SU48 RS02070
gene id: 1182568:SU48_RS02070
uniprot id: A0A172T7E6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1182568:SU48 RS07515
gene id: 1182568:SU48_RS07515
uniprot id: A0A172T9N2
names: Similarity
messages: Belongs to the FemABX family.

1182568:SU48 RS09555
gene id: 1182568:SU48_RS09555
uniprot id: A0A172TAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1182568:SU48 RS05585
gene id: 1182568:SU48_RS05585
uniprot id: A0A172T8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1182568:SU48 RS13630
gene id: 1182568:SU48_RS13630
uniprot id: A0A172TC72
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1182568:SU48 RS07375
gene id: 1182568:SU48_RS07375
uniprot id: A0A172T9J2
names: Similarity
messages: Belongs to the UPF0225 family.

1182568:SU48 RS09595
gene id: 1182568:SU48_RS09595
uniprot id: A0A172TAE6
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS00950
gene id: 1182568:SU48_RS00950
uniprot id: A0A172T6I3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1182568:SU48 RS12870
gene id: 1182568:SU48_RS12870
uniprot id: A0A172TBV4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1182568:SU48 RS11345
gene id: 1182568:SU48_RS11345
uniprot id: A0A172TB72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1182568:SU48 RS10870
gene id: 1182568:SU48_RS10870
uniprot id: A0A172TB49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1182568:SU48 RS01410
gene id: 1182568:SU48_RS01410
uniprot id: A0A172T6N1
names: Similarity
messages: Belongs to the peptidase C1 family.

1182568:SU48 RS10730
gene id: 1182568:SU48_RS10730
uniprot id: A0A172TAW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1182568:SU48 RS08070
gene id: 1182568:SU48_RS08070
uniprot id: A0A172T9V5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS13145
gene id: 1182568:SU48_RS13145
uniprot id: A0A172TC65
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1182568:SU48 RS01205
gene id: 1182568:SU48_RS01205
uniprot id: A0A172T6M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1182568:SU48 RS00195
gene id: 1182568:SU48_RS00195
uniprot id: A0A172T635
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1182568:SU48 RS04775
gene id: 1182568:SU48_RS04775
uniprot id: A0A172TCW3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1182568:SU48 RS03420
gene id: 1182568:SU48_RS03420
uniprot id: A0A172T7Q0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1182568:SU48 RS00375
gene id: 1182568:SU48_RS00375
uniprot id: A0A172T670
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1182568:SU48 RS05535
gene id: 1182568:SU48_RS05535
uniprot id: A0A172T8K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1182568:SU48 RS08700
gene id: 1182568:SU48_RS08700
uniprot id: A0A172TA79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1182568:SU48 RS03415
gene id: 1182568:SU48_RS03415
uniprot id: A0A172T7R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1182568:SU48 RS00525
gene id: 1182568:SU48_RS00525
uniprot id: A0A172T633
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1182568:SU48 RS03435
gene id: 1182568:SU48_RS03435
uniprot id: A0A172T7M2
names: Similarity
messages: Belongs to the peptidase S8 family.

1182568:SU48 RS09160
gene id: 1182568:SU48_RS09160
uniprot id: A0A172TA58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS12050
gene id: 1182568:SU48_RS12050
uniprot id: A0A172TBP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1182568:SU48 RS03960
gene id: 1182568:SU48_RS03960
uniprot id: A0A172T8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1182568:SU48 RS05795
gene id: 1182568:SU48_RS05795
uniprot id: A0A172T8M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1182568:SU48 RS01055
gene id: 1182568:SU48_RS01055
uniprot id: A0A172T6H3
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS12060
gene id: 1182568:SU48_RS12060
uniprot id: A0A172TBS9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1182568:SU48 RS02560
gene id: 1182568:SU48_RS02560
uniprot id: A0A172T7A1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1182568:SU48 RS01070
gene id: 1182568:SU48_RS01070
uniprot id: A0A172T6K4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1182568:SU48 RS13210
gene id: 1182568:SU48_RS13210
uniprot id: A0A172TC48
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1182568:SU48 RS00030
gene id: 1182568:SU48_RS00030
uniprot id: A0A172T609
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1182568:SU48 RS02525
gene id: 1182568:SU48_RS02525
uniprot id: A0A172TCH1
names: Similarity
messages: Belongs to the ArsC family.

1182568:SU48 RS10700
gene id: 1182568:SU48_RS10700
uniprot id: A0A172TB59
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1182568:SU48 RS11615
gene id: 1182568:SU48_RS11615
uniprot id: A0A172TBK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1182568:SU48 RS01320
gene id: 1182568:SU48_RS01320
uniprot id: A0A172T6F8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1182568:SU48 RS10110
gene id: 1182568:SU48_RS10110
uniprot id: A0A172TAP6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1182568:SU48 RS05110
gene id: 1182568:SU48_RS05110
uniprot id: A0A172T8D5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS09725
gene id: 1182568:SU48_RS09725
uniprot id: A0A172TB20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1182568:SU48 RS07275
gene id: 1182568:SU48_RS07275
uniprot id: A0A172T9W8
names: Similarity
messages: Belongs to the aspartokinase family.

1182568:SU48 RS04220
gene id: 1182568:SU48_RS04220
uniprot id: A0A172T7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

1182568:SU48 RS12845
gene id: 1182568:SU48_RS12845
uniprot id: A0A172TCH2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1182568:SU48 RS12220
gene id: 1182568:SU48_RS12220
uniprot id: A0A172TBL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1182568:SU48 RS03260
gene id: 1182568:SU48_RS03260
uniprot id: A0A172T7I7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1182568:SU48 RS04975
gene id: 1182568:SU48_RS04975
uniprot id: A0A172T8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1182568:SU48 RS01840
gene id: 1182568:SU48_RS01840
uniprot id: A0A172T6Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1182568:SU48 RS12940
gene id: 1182568:SU48_RS12940
uniprot id: A0A172TC37
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1182568:SU48 RS12960
gene id: 1182568:SU48_RS12960
uniprot id: A0A172TBY0
names: Similarity
messages: Belongs to the peptidase M16 family.

1182568:SU48 RS04605
gene id: 1182568:SU48_RS04605
uniprot id: A0A172T818
names: Similarity
messages: Belongs to the asp23 family.

1182568:SU48 RS10800
gene id: 1182568:SU48_RS10800
uniprot id: A0A172TAX7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1182568:SU48 RS06870
gene id: 1182568:SU48_RS06870
uniprot id: A0A172T926
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS00235
gene id: 1182568:SU48_RS00235
uniprot id: A0A172T5Z2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1182568:SU48 RS12810
gene id: 1182568:SU48_RS12810
uniprot id: A0A172TC18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1182568:SU48 RS13395
gene id: 1182568:SU48_RS13395
uniprot id: A0A172TC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS03340
gene id: 1182568:SU48_RS03340
uniprot id: A0A172T7P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1182568:SU48 RS04980
gene id: 1182568:SU48_RS04980
uniprot id: A0A172T864
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1182568:SU48 RS01290
gene id: 1182568:SU48_RS01290
uniprot id: A0A172T6F7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1182568:SU48 RS04110
gene id: 1182568:SU48_RS04110
uniprot id: A0A172T7S7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1182568:SU48 RS03555
gene id: 1182568:SU48_RS03555
uniprot id: A0A172T7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1182568:SU48 RS02505
gene id: 1182568:SU48_RS02505
uniprot id: A0A172T757
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1182568:SU48 RS10165
gene id: 1182568:SU48_RS10165
uniprot id: A0A172TAU5
names: Subcellular Location Annotation
messages: Membrane

1182568:SU48 RS05090
gene id: 1182568:SU48_RS05090
uniprot id: A0A172T8H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1182568:SU48 RS03820
gene id: 1182568:SU48_RS03820
uniprot id: A0A172T7S2
names: Similarity
messages: Belongs to the SCO1/2 family.

1182568:SU48 RS04460
gene id: 1182568:SU48_RS04460
uniprot id: A0A172T865
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1182568:SU48 RS10970
gene id: 1182568:SU48_RS10970
uniprot id: A0A172TD54
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1182568:SU48 RS01225
gene id: 1182568:SU48_RS01225
uniprot id: A0A172T6F3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1182568:SU48 RS06125
gene id: 1182568:SU48_RS06125
uniprot id: A0A172T8R0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1182568:SU48 RS09430
gene id: 1182568:SU48_RS09430
uniprot id: A0A172TAA8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1182568:SU48 RS01860
gene id: 1182568:SU48_RS01860
uniprot id: A0A172T6U8
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS13615
gene id: 1182568:SU48_RS13615
uniprot id: A0A172TC39
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

1182568:SU48 RS09620
gene id: 1182568:SU48_RS09620
uniprot id: A0A172TAM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1182568:SU48 RS01795
gene id: 1182568:SU48_RS01795
uniprot id: A0A172T6X1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1182568:SU48 RS04520
gene id: 1182568:SU48_RS04520
uniprot id: A0A172T7Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1182568:SU48 RS02200
gene id: 1182568:SU48_RS02200
uniprot id: A0A172T6V9
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS12000
gene id: 1182568:SU48_RS12000
uniprot id: A0A172TBG9
names: Similarity
messages: Belongs to the UPF0102 family.

1182568:SU48 RS03115
gene id: 1182568:SU48_RS03115
uniprot id: A0A172T7K2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1182568:SU48 RS06720
gene id: 1182568:SU48_RS06720
uniprot id: A0A172T991
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1182568:SU48 RS09250
gene id: 1182568:SU48_RS09250
uniprot id: A0A172TAU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1182568:SU48 RS10785
gene id: 1182568:SU48_RS10785
uniprot id: A0A172TB45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1182568:SU48 RS02910
gene id: 1182568:SU48_RS02910
uniprot id: A0A172T7C3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1182568:SU48 RS02750
gene id: 1182568:SU48_RS02750
uniprot id: A0A172T7Q9
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1182568:SU48 RS05560
gene id: 1182568:SU48_RS05560
uniprot id: A0A172T939
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1182568:SU48 RS06730
gene id: 1182568:SU48_RS06730
uniprot id: A0A172T994
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS05005
gene id: 1182568:SU48_RS05005
uniprot id: A0A172TCZ9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1182568:SU48 RS02970
gene id: 1182568:SU48_RS02970
uniprot id: A0A172T7D3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1182568:SU48 RS03010
gene id: 1182568:SU48_RS03010
uniprot id: A0A172T7J7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1182568:SU48 RS05580
gene id: 1182568:SU48_RS05580
uniprot id: A0A172T8Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1182568:SU48 RS00515
gene id: 1182568:SU48_RS00515
uniprot id: A0A172T6Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1182568:SU48 RS09050
gene id: 1182568:SU48_RS09050
uniprot id: A0A172TA73
names: Similarity
messages: Belongs to the citrate synthase family.

1182568:SU48 RS03975
gene id: 1182568:SU48_RS03975
uniprot id: A0A172T7Z3
names: Subcellular Location Annotation
messages: Periplasm

1182568:SU48 RS12930
gene id: 1182568:SU48_RS12930
uniprot id: A0A172TDK8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1182568:SU48 RS12955
gene id: 1182568:SU48_RS12955
uniprot id: A0A172TBW5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1182568:SU48 RS13245
gene id: 1182568:SU48_RS13245
uniprot id: A0A172TCC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1182568:SU48 RS01900
gene id: 1182568:SU48_RS01900
uniprot id: A0A172T6Z0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1182568:SU48 RS04690
gene id: 1182568:SU48_RS04690
uniprot id: A0A172T819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1182568:SU48 RS09415
gene id: 1182568:SU48_RS09415
uniprot id: A0A172TAH6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1182568:SU48 RS00930
gene id: 1182568:SU48_RS00930
uniprot id: A0A172T6F1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1182568:SU48 RS10215
gene id: 1182568:SU48_RS10215
uniprot id: A0A172TAN9
names: Similarity
messages: Belongs to the YciI family.

1182568:SU48 RS07495
gene id: 1182568:SU48_RS07495
uniprot id: A0A172TA09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1182568:SU48 RS10725
gene id: 1182568:SU48_RS10725
uniprot id: A0A172TAX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1182568:SU48 RS00345
gene id: 1182568:SU48_RS00345
uniprot id: A0A172T5Z5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.