118060:ATZ35 RS08525
gene id: 118060:ATZ35_RS08525
uniprot id: A0A0U2MWZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

118060:ATZ35 RS05600
gene id: 118060:ATZ35_RS05600
uniprot id: A0A0U2X6Y6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

118060:ATZ35 RS03210
gene id: 118060:ATZ35_RS03210
uniprot id: A0A0U2VET0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

118060:ATZ35 RS06095
gene id: 118060:ATZ35_RS06095
uniprot id: A0A0U2WXG4
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

118060:ATZ35 RS05235
gene id: 118060:ATZ35_RS05235
uniprot id: A0A0U2NPB0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

118060:ATZ35 RS09025
gene id: 118060:ATZ35_RS09025
uniprot id: A0A0U2IUB8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

118060:ATZ35 RS03175
gene id: 118060:ATZ35_RS03175
uniprot id: A0A0U2LUA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

118060:ATZ35 RS02940
gene id: 118060:ATZ35_RS02940
uniprot id: A0A0U2WRF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

118060:ATZ35 RS04010
gene id: 118060:ATZ35_RS04010
uniprot id: A0A0U2XG90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

118060:ATZ35 RS02950
gene id: 118060:ATZ35_RS02950
uniprot id: A0A0U2VF42
names: Similarity
messages: Belongs to the LOG family.

118060:ATZ35 RS03130
gene id: 118060:ATZ35_RS03130
uniprot id: A0A0U2VER4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

118060:ATZ35 RS03170
gene id: 118060:ATZ35_RS03170
uniprot id: A0A0U2VS50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

118060:ATZ35 RS12045
gene id: 118060:ATZ35_RS12045
uniprot id: A0A0U2WVZ7
names: Similarity
messages: Belongs to the UPF0473 family.

118060:ATZ35 RS13935
gene id: 118060:ATZ35_RS13935
uniprot id: A0A0U2XDI3
names: Similarity
messages: Belongs to the thioredoxin family.

118060:ATZ35 RS14280
gene id: 118060:ATZ35_RS14280
uniprot id: A0A0U2X1N5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

118060:ATZ35 RS10105
gene id: 118060:ATZ35_RS10105
uniprot id: A0A0U2XBF7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

118060:ATZ35 RS03200
gene id: 118060:ATZ35_RS03200
uniprot id: A0A0U2WW01
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

118060:ATZ35 RS05130
gene id: 118060:ATZ35_RS05130
uniprot id: A0A0U2XGU6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

118060:ATZ35 RS16315
gene id: 118060:ATZ35_RS16315
uniprot id: A0A0U2XF32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

118060:ATZ35 RS05885
gene id: 118060:ATZ35_RS05885
uniprot id: A0A0U2LVD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

118060:ATZ35 RS03165
gene id: 118060:ATZ35_RS03165
uniprot id: A0A0U2MV75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

118060:ATZ35 RS03305
gene id: 118060:ATZ35_RS03305
uniprot id: A0A0U2ITX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

118060:ATZ35 RS03090
gene id: 118060:ATZ35_RS03090
uniprot id: A0A0U2VS32
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

118060:ATZ35 RS05150
gene id: 118060:ATZ35_RS05150
uniprot id: A0A0U2XCQ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

118060:ATZ35 RS08490
gene id: 118060:ATZ35_RS08490
uniprot id: A0A0U2XIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

118060:ATZ35 RS11750
gene id: 118060:ATZ35_RS11750
uniprot id: A0A0U2XC79
names: Similarity
messages: Belongs to the UPF0234 family.

118060:ATZ35 RS03630
gene id: 118060:ATZ35_RS03630
uniprot id: A0A0U2XG28
names: Function
names: PTM
names: Similarity
messages: Belongs to the type A lantibiotic family.
messages: Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
messages: Maturation of lantibiotics involves the enzymatic conversion of Thr, and Ser into dehydrated AA and the formation of thioether bonds with cysteine. This is followed by membrane translocation and cleavage of the modified precursor.

118060:ATZ35 RS03310
gene id: 118060:ATZ35_RS03310
uniprot id: A0A0U2VP44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

118060:ATZ35 RS03040
gene id: 118060:ATZ35_RS03040
uniprot id: A0A0U2WVX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

118060:ATZ35 RS03125
gene id: 118060:ATZ35_RS03125
uniprot id: A0A0U2VF69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

118060:ATZ35 RS03225
gene id: 118060:ATZ35_RS03225
uniprot id: A0A0U2VP22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

118060:ATZ35 RS00900
gene id: 118060:ATZ35_RS00900
uniprot id: A0A0U2X4P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

118060:ATZ35 RS08400
gene id: 118060:ATZ35_RS08400
uniprot id: A0A0U2XIU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

118060:ATZ35 RS00765
gene id: 118060:ATZ35_RS00765
uniprot id: A0A0U2XEF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

118060:ATZ35 RS00710
gene id: 118060:ATZ35_RS00710
uniprot id: A0A0U2NMF2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

118060:ATZ35 RS03115
gene id: 118060:ATZ35_RS03115
uniprot id: A0A0U2WRI8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

118060:ATZ35 RS05185
gene id: 118060:ATZ35_RS05185
uniprot id: A0A0U2X907
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

118060:ATZ35 RS03135
gene id: 118060:ATZ35_RS03135
uniprot id: A0A0U2XFT4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

118060:ATZ35 RS15925
gene id: 118060:ATZ35_RS15925
uniprot id: A0A0U2VW68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

118060:ATZ35 RS04265
gene id: 118060:ATZ35_RS04265
uniprot id: A0A0U2ITZ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

118060:ATZ35 RS05475
gene id: 118060:ATZ35_RS05475
uniprot id: A0A0U2X940
names: Similarity
messages: Belongs to the WXG100 family.

118060:ATZ35 RS03155
gene id: 118060:ATZ35_RS03155
uniprot id: A0A0U2XBQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

118060:ATZ35 RS09255
gene id: 118060:ATZ35_RS09255
uniprot id: A0A0U2WZ41
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

118060:ATZ35 RS03035
gene id: 118060:ATZ35_RS03035
uniprot id: A0A0U2WRH5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

118060:ATZ35 RS07595
gene id: 118060:ATZ35_RS07595
uniprot id: A0A0U2WYA3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

118060:ATZ35 RS03220
gene id: 118060:ATZ35_RS03220
uniprot id: A0A0U2ITW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

118060:ATZ35 RS04350
gene id: 118060:ATZ35_RS04350
uniprot id: A0A0U2VPQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

118060:ATZ35 RS03150
gene id: 118060:ATZ35_RS03150
uniprot id: A0A0U2X7N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

118060:ATZ35 RS15030
gene id: 118060:ATZ35_RS15030
uniprot id: A0A0U2WXJ9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

118060:ATZ35 RS12420
gene id: 118060:ATZ35_RS12420
uniprot id: A0A0U2VK52
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

118060:ATZ35 RS08920
gene id: 118060:ATZ35_RS08920
uniprot id: A0A0U2XJ28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

118060:ATZ35 RS11075
gene id: 118060:ATZ35_RS11075
uniprot id: A0A0U2VWK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

118060:ATZ35 RS03100
gene id: 118060:ATZ35_RS03100
uniprot id: A0A0U2WLQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

118060:ATZ35 RS03050
gene id: 118060:ATZ35_RS03050
uniprot id: A0A0U2VEN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

118060:ATZ35 RS14120
gene id: 118060:ATZ35_RS14120
uniprot id: A0A0U2VL67
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

118060:ATZ35 RS13560
gene id: 118060:ATZ35_RS13560
uniprot id: A0A0U2XD97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

118060:ATZ35 RS00720
gene id: 118060:ATZ35_RS00720
uniprot id: A0A0U2VQQ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

118060:ATZ35 RS15275
gene id: 118060:ATZ35_RS15275
uniprot id: A0A0U2XBW3
names: Subcellular Location Annotation
messages: Cell membrane

118060:ATZ35 RS11090
gene id: 118060:ATZ35_RS11090
uniprot id: A0A0U2X9W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

118060:ATZ35 RS03190
gene id: 118060:ATZ35_RS03190
uniprot id: A0A0U2X7Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

118060:ATZ35 RS05890
gene id: 118060:ATZ35_RS05890
uniprot id: A0A0U2WN66
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

118060:ATZ35 RS11315
gene id: 118060:ATZ35_RS11315
uniprot id: A0A0U2XG31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

118060:ATZ35 RS04630
gene id: 118060:ATZ35_RS04630
uniprot id: A0A0U2IUY3
names: Subcellular Location Annotation
messages: Membrane

118060:ATZ35 RS02970
gene id: 118060:ATZ35_RS02970
uniprot id: A0A0U2VNX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

118060:ATZ35 RS05000
gene id: 118060:ATZ35_RS05000
uniprot id: A0A0U2VTA9
names: Subcellular Location Annotation
messages: Membrane

118060:ATZ35 RS03095
gene id: 118060:ATZ35_RS03095
uniprot id: A0A0U2LU95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

118060:ATZ35 RS14650
gene id: 118060:ATZ35_RS14650
uniprot id: A0A0U2VLG9
names: Subcellular Location Annotation
messages: Cytoplasm

118060:ATZ35 RS01760
gene id: 118060:ATZ35_RS01760
uniprot id: A0A0U2LTS3
names: Subcellular Location Annotation
messages: Cytoplasm

118060:ATZ35 RS10645
gene id: 118060:ATZ35_RS10645
uniprot id: A0A0U2WQP7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

118060:ATZ35 RS05140
gene id: 118060:ATZ35_RS05140
uniprot id: A0A0U2VQ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

118060:ATZ35 RS11420
gene id: 118060:ATZ35_RS11420
uniprot id: A0A0U2LX50
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

118060:ATZ35 RS15950
gene id: 118060:ATZ35_RS15950
uniprot id: A0A0U2VZ27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

118060:ATZ35 RS02285
gene id: 118060:ATZ35_RS02285
uniprot id: A0A0U2VEP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

118060:ATZ35 RS07970
gene id: 118060:ATZ35_RS07970
uniprot id: A0A0U2WYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

118060:ATZ35 RS00825
gene id: 118060:ATZ35_RS00825
uniprot id: A0A0U2X6U1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

118060:ATZ35 RS10120
gene id: 118060:ATZ35_RS10120
uniprot id: A0A0U2MXG2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

118060:ATZ35 RS08495
gene id: 118060:ATZ35_RS08495
uniprot id: A0A0U2IUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

118060:ATZ35 RS04220
gene id: 118060:ATZ35_RS04220
uniprot id: A0A0U2LUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

118060:ATZ35 RS16495
gene id: 118060:ATZ35_RS16495
uniprot id: A0A0U2VMB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

118060:ATZ35 RS01480
gene id: 118060:ATZ35_RS01480
uniprot id: A0A0U2VN03
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

118060:ATZ35 RS03500
gene id: 118060:ATZ35_RS03500
uniprot id: A0A0U2LUF7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

118060:ATZ35 RS15930
gene id: 118060:ATZ35_RS15930
uniprot id: A0A0U2XEC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

118060:ATZ35 RS12760
gene id: 118060:ATZ35_RS12760
uniprot id: A0A0U2XAP4
names: Subcellular Location Annotation
messages: Cytoplasm

118060:ATZ35 RS03295
gene id: 118060:ATZ35_RS03295
uniprot id: A0A0U2VEV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

118060:ATZ35 RS01355
gene id: 118060:ATZ35_RS01355
uniprot id: A0A0U2XEX4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

118060:ATZ35 RS03160
gene id: 118060:ATZ35_RS03160
uniprot id: A0A0U2NNE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

118060:ATZ35 RS02155
gene id: 118060:ATZ35_RS02155
uniprot id: A0A0U2XB19
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

118060:ATZ35 RS15395
gene id: 118060:ATZ35_RS15395
uniprot id: A0A0U2XMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

118060:ATZ35 RS01190
gene id: 118060:ATZ35_RS01190
uniprot id: A0A0U2ITR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

118060:ATZ35 RS03145
gene id: 118060:ATZ35_RS03145
uniprot id: A0A0U2VP04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

118060:ATZ35 RS04040
gene id: 118060:ATZ35_RS04040
uniprot id: A0A0U2MVG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

118060:ATZ35 RS03045
gene id: 118060:ATZ35_RS03045
uniprot id: A0A0U2VF57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

118060:ATZ35 RS03105
gene id: 118060:ATZ35_RS03105
uniprot id: A0A0U2X5S2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

118060:ATZ35 RS15910
gene id: 118060:ATZ35_RS15910
uniprot id: A0A0U2VM67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

118060:ATZ35 RS03635
gene id: 118060:ATZ35_RS03635
uniprot id: A0A0U2XG28
names: Function
names: PTM
names: Similarity
messages: Belongs to the type A lantibiotic family.
messages: Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
messages: Maturation of lantibiotics involves the enzymatic conversion of Thr, and Ser into dehydrated AA and the formation of thioether bonds with cysteine. This is followed by membrane translocation and cleavage of the modified precursor.

118060:ATZ35 RS04260
gene id: 118060:ATZ35_RS04260
uniprot id: A0A0U2XGC9
names: Similarity
messages: Belongs to the asp23 family.

118060:ATZ35 RS12035
gene id: 118060:ATZ35_RS12035
uniprot id: A0A0U2XAC6
names: Similarity
messages: Belongs to the UPF0297 family.

118060:ATZ35 RS15895
gene id: 118060:ATZ35_RS15895
uniprot id: A0A0U2WXZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

118060:ATZ35 RS00655
gene id: 118060:ATZ35_RS00655
uniprot id: A0A0U2X6Q7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

118060:ATZ35 RS04825
gene id: 118060:ATZ35_RS04825
uniprot id: A0A0U2MVQ4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

118060:ATZ35 RS12250
gene id: 118060:ATZ35_RS12250
uniprot id: A0A0U2VK09
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

118060:ATZ35 RS03640
gene id: 118060:ATZ35_RS03640
uniprot id: A0A0U2XG28
names: Function
names: PTM
names: Similarity
messages: Belongs to the type A lantibiotic family.
messages: Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
messages: Maturation of lantibiotics involves the enzymatic conversion of Thr, and Ser into dehydrated AA and the formation of thioether bonds with cysteine. This is followed by membrane translocation and cleavage of the modified precursor.

118060:ATZ35 RS04240
gene id: 118060:ATZ35_RS04240
uniprot id: A0A0U2WS48
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

118060:ATZ35 RS10935
gene id: 118060:ATZ35_RS10935
uniprot id: A0A0U2VJE4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

118060:ATZ35 RS01275
gene id: 118060:ATZ35_RS01275
uniprot id: A0A0U2ITR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

118060:ATZ35 RS03110
gene id: 118060:ATZ35_RS03110
uniprot id: A0A0U2X7X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

118060:ATZ35 RS16105
gene id: 118060:ATZ35_RS16105
uniprot id: A0A0U2NTP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

118060:ATZ35 RS03300
gene id: 118060:ATZ35_RS03300
uniprot id: A0A0U2XFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

118060:ATZ35 RS03180
gene id: 118060:ATZ35_RS03180
uniprot id: A0A0U2WLR5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

118060:ATZ35 RS00790
gene id: 118060:ATZ35_RS00790
uniprot id: A0A0U2NMG3
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

118060:ATZ35 RS00495
gene id: 118060:ATZ35_RS00495
uniprot id: A0A0U2WQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

118060:ATZ35 RS03355
gene id: 118060:ATZ35_RS03355
uniprot id: A0A0U2X812
names: Subcellular Location Annotation
messages: Membrane

118060:ATZ35 RS10055
gene id: 118060:ATZ35_RS10055
uniprot id: A0A0U2WQD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

118060:ATZ35 RS03055
gene id: 118060:ATZ35_RS03055
uniprot id: A0A0U2XFS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

118060:ATZ35 RS03020
gene id: 118060:ATZ35_RS03020
uniprot id: A0A0U2WLN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

118060:ATZ35 RS12925
gene id: 118060:ATZ35_RS12925
uniprot id: A0A0U2WRV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

118060:ATZ35 RS03195
gene id: 118060:ATZ35_RS03195
uniprot id: A0A0U2WRK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

118060:ATZ35 RS04205
gene id: 118060:ATZ35_RS04205
uniprot id: A0A0U2NNU9
names: Similarity
messages: Belongs to the NDK family.

118060:ATZ35 RS08415
gene id: 118060:ATZ35_RS08415
uniprot id: A0A0U2XAN3
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

118060:ATZ35 RS03085
gene id: 118060:ATZ35_RS03085
uniprot id: A0A0U2MV62
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

118060:ATZ35 RS13070
gene id: 118060:ATZ35_RS13070
uniprot id: A0A0U2XCY9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

118060:ATZ35 RS05270
gene id: 118060:ATZ35_RS05270
uniprot id: A0A0U2WSQ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

118060:ATZ35 RS10640
gene id: 118060:ATZ35_RS10640
uniprot id: A0A0U2LWV1
names: Subcellular Location Annotation
messages: Membrane

118060:ATZ35 RS03185
gene id: 118060:ATZ35_RS03185
uniprot id: A0A0U2X5T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

118060:ATZ35 RS03025
gene id: 118060:ATZ35_RS03025
uniprot id: A0A0U2X5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

118060:ATZ35 RS03030
gene id: 118060:ATZ35_RS03030
uniprot id: A0A0U2X7W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

118060:ATZ35 RS08910
gene id: 118060:ATZ35_RS08910
uniprot id: A0A0U2VIC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

118060:ATZ35 RS11405
gene id: 118060:ATZ35_RS11405
uniprot id: A0A0U2NRU0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

118060:ATZ35 RS11795
gene id: 118060:ATZ35_RS11795
uniprot id: A0A0U2WVV0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

118060:ATZ35 RS08530
gene id: 118060:ATZ35_RS08530
uniprot id: A0A0U2VV53
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.