1178516:AWR27 RS01785
gene id: 1178516:AWR27_RS01785
uniprot id: A0A1P9WS26
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1178516:AWR27 RS01185
gene id: 1178516:AWR27_RS01185
uniprot id: A0A1P9WRS6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1178516:AWR27 RS02295
gene id: 1178516:AWR27_RS02295
uniprot id: A0A1P9X3S2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1178516:AWR27 RS02670
gene id: 1178516:AWR27_RS02670
uniprot id: A0A1P9WSI3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS12715
gene id: 1178516:AWR27_RS12715
uniprot id: A0A1P9WXK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS16075
gene id: 1178516:AWR27_RS16075
uniprot id: A0A1P9WZA9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1178516:AWR27 RS01465
gene id: 1178516:AWR27_RS01465
uniprot id: A0A1P9WRZ5
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS09125
gene id: 1178516:AWR27_RS09125
uniprot id: A0A1P9WVQ1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1178516:AWR27 RS21610
gene id: 1178516:AWR27_RS21610
uniprot id: A0A1P9X1X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1178516:AWR27 RS15850
gene id: 1178516:AWR27_RS15850
uniprot id: A0A1P9WZ36
names: Similarity
messages: Belongs to the peptidase M4 family.

1178516:AWR27 RS06260
gene id: 1178516:AWR27_RS06260
uniprot id: A0A1P9WU93
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS12905
gene id: 1178516:AWR27_RS12905
uniprot id: A0A1P9WXP1
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS19060
gene id: 1178516:AWR27_RS19060
uniprot id: A0A1P9X0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1178516:AWR27 RS10125
gene id: 1178516:AWR27_RS10125
uniprot id: A0A1P9WW80
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1178516:AWR27 RS03615
gene id: 1178516:AWR27_RS03615
uniprot id: A0A1P9WSZ2
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS19760
gene id: 1178516:AWR27_RS19760
uniprot id: A0A1P9X4S7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1178516:AWR27 RS17730
gene id: 1178516:AWR27_RS17730
uniprot id: A0A1P9X036
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1178516:AWR27 RS08285
gene id: 1178516:AWR27_RS08285
uniprot id: A0A1P9WV78
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1178516:AWR27 RS18470
gene id: 1178516:AWR27_RS18470
uniprot id: A0A1P9X0D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1178516:AWR27 RS12050
gene id: 1178516:AWR27_RS12050
uniprot id: A0A1P9WX76
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1178516:AWR27 RS14670
gene id: 1178516:AWR27_RS14670
uniprot id: A0A1P9WYH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1178516:AWR27 RS13200
gene id: 1178516:AWR27_RS13200
uniprot id: A0A1P9WXQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1178516:AWR27 RS00755
gene id: 1178516:AWR27_RS00755
uniprot id: A0A1P9WRJ9
names: Similarity
messages: Belongs to the sulfatase family.

1178516:AWR27 RS06325
gene id: 1178516:AWR27_RS06325
uniprot id: A0A1P9WUE7
names: Similarity
messages: Belongs to the peptidase S66 family.

1178516:AWR27 RS17750
gene id: 1178516:AWR27_RS17750
uniprot id: A0A1P9X029
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS21975
gene id: 1178516:AWR27_RS21975
uniprot id: A0A1P9X277
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1178516:AWR27 RS22540
gene id: 1178516:AWR27_RS22540
uniprot id: A0A1P9X2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1178516:AWR27 RS18860
gene id: 1178516:AWR27_RS18860
uniprot id: A0A1P9X0L9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1178516:AWR27 RS23400
gene id: 1178516:AWR27_RS23400
uniprot id: A0A1P9X2V9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS07400
gene id: 1178516:AWR27_RS07400
uniprot id: A0A1P9WUU3
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS20410
gene id: 1178516:AWR27_RS20410
uniprot id: A0A1P9X1H3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1178516:AWR27 RS23805
gene id: 1178516:AWR27_RS23805
uniprot id: A0A1P9X341
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1178516:AWR27 RS12465
gene id: 1178516:AWR27_RS12465
uniprot id: A0A1P9WXH4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1178516:AWR27 RS03545
gene id: 1178516:AWR27_RS03545
uniprot id: A0A1P9WSX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1178516:AWR27 RS14115
gene id: 1178516:AWR27_RS14115
uniprot id: A0A1P9WY80
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

1178516:AWR27 RS09630
gene id: 1178516:AWR27_RS09630
uniprot id: A0A1P9WVY7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1178516:AWR27 RS03510
gene id: 1178516:AWR27_RS03510
uniprot id: A0A1P9WSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1178516:AWR27 RS04135
gene id: 1178516:AWR27_RS04135
uniprot id: A0A1P9X3T6
names: Subunit
messages: Homodimer.

1178516:AWR27 RS00085
gene id: 1178516:AWR27_RS00085
uniprot id: A0A1P9WR98
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS04585
gene id: 1178516:AWR27_RS04585
uniprot id: A0A1P9WTH0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1178516:AWR27 RS00305
gene id: 1178516:AWR27_RS00305
uniprot id: A0A1P9WRD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1178516:AWR27 RS22000
gene id: 1178516:AWR27_RS22000
uniprot id: A0A1P9X274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1178516:AWR27 RS14040
gene id: 1178516:AWR27_RS14040
uniprot id: A0A1P9WY55
names: Similarity
messages: Belongs to the MoaD family.

1178516:AWR27 RS03200
gene id: 1178516:AWR27_RS03200
uniprot id: A0A1P9WST7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1178516:AWR27 RS24100
gene id: 1178516:AWR27_RS24100
uniprot id: A0A1P9X394
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS08400
gene id: 1178516:AWR27_RS08400
uniprot id: A0A1P9WVA9
names: Similarity
messages: Belongs to the thioredoxin family.

1178516:AWR27 RS15025
gene id: 1178516:AWR27_RS15025
uniprot id: A0A1P9WYQ6
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS20550
gene id: 1178516:AWR27_RS20550
uniprot id: A0A1P9X1E4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1178516:AWR27 RS09985
gene id: 1178516:AWR27_RS09985
uniprot id: A0A1P9WW46
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1178516:AWR27 RS21840
gene id: 1178516:AWR27_RS21840
uniprot id: A0A1P9X257
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1178516:AWR27 RS12280
gene id: 1178516:AWR27_RS12280
uniprot id: A0A1P9WXA0
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS00715
gene id: 1178516:AWR27_RS00715
uniprot id: A0A1P9WRK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1178516:AWR27 RS06110
gene id: 1178516:AWR27_RS06110
uniprot id: A0A1P9WU66
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1178516:AWR27 RS04730
gene id: 1178516:AWR27_RS04730
uniprot id: A0A1P9WTI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS05240
gene id: 1178516:AWR27_RS05240
uniprot id: A0A1P9WTR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1178516:AWR27 RS19295
gene id: 1178516:AWR27_RS19295
uniprot id: A0A1P9X0U1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS24210
gene id: 1178516:AWR27_RS24210
uniprot id: A0A1P9X377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS23450
gene id: 1178516:AWR27_RS23450
uniprot id: A0A1P9X2U6
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS09015
gene id: 1178516:AWR27_RS09015
uniprot id: A0A1P9WVM1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS23830
gene id: 1178516:AWR27_RS23830
uniprot id: A0A1P9X306
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1178516:AWR27 RS00180
gene id: 1178516:AWR27_RS00180
uniprot id: A0A1P9WRB2
names: Similarity
messages: Belongs to the arginine deiminase family.

1178516:AWR27 RS03530
gene id: 1178516:AWR27_RS03530
uniprot id: A0A1P9WSZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS22115
gene id: 1178516:AWR27_RS22115
uniprot id: A0A1P9X258
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1178516:AWR27 RS07975
gene id: 1178516:AWR27_RS07975
uniprot id: A0A1P9WV32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1178516:AWR27 RS16495
gene id: 1178516:AWR27_RS16495
uniprot id: A0A1P9X4G8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1178516:AWR27 RS07340
gene id: 1178516:AWR27_RS07340
uniprot id: A0A1P9X400
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1178516:AWR27 RS18055
gene id: 1178516:AWR27_RS18055
uniprot id: A0A1P9X083
names: Similarity
messages: Belongs to the UPF0102 family.

1178516:AWR27 RS10990
gene id: 1178516:AWR27_RS10990
uniprot id: A0A1P9WWM9
names: Similarity
messages: Belongs to the CinA family.

1178516:AWR27 RS11685
gene id: 1178516:AWR27_RS11685
uniprot id: A0A1P9WWZ6
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1178516:AWR27 RS21675
gene id: 1178516:AWR27_RS21675
uniprot id: A0A1P9X201
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS23900
gene id: 1178516:AWR27_RS23900
uniprot id: A0A1P9X344
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1178516:AWR27 RS11770
gene id: 1178516:AWR27_RS11770
uniprot id: A0A1P9WX39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1178516:AWR27 RS08780
gene id: 1178516:AWR27_RS08780
uniprot id: A0A1P9WVJ2
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1178516:AWR27 RS08595
gene id: 1178516:AWR27_RS08595
uniprot id: A0A1P9WVD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1178516:AWR27 RS10790
gene id: 1178516:AWR27_RS10790
uniprot id: A0A1P9WWN4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1178516:AWR27 RS02115
gene id: 1178516:AWR27_RS02115
uniprot id: A0A1P9WS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1178516:AWR27 RS06270
gene id: 1178516:AWR27_RS06270
uniprot id: A0A1P9WUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1178516:AWR27 RS05370
gene id: 1178516:AWR27_RS05370
uniprot id: A0A1P9WTU3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1178516:AWR27 RS19455
gene id: 1178516:AWR27_RS19455
uniprot id: A0A1P9X0W3
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS09285
gene id: 1178516:AWR27_RS09285
uniprot id: A0A1P9WVU1
names: Subcellular Location Annotation
messages: Nucleus

1178516:AWR27 RS14120
gene id: 1178516:AWR27_RS14120
uniprot id: A0A1P9WY90
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1178516:AWR27 RS19800
gene id: 1178516:AWR27_RS19800
uniprot id: A0A1P9X127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1178516:AWR27 RS05060
gene id: 1178516:AWR27_RS05060
uniprot id: A0A1P9WTS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1178516:AWR27 RS03170
gene id: 1178516:AWR27_RS03170
uniprot id: A0A1P9WST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1178516:AWR27 RS04840
gene id: 1178516:AWR27_RS04840
uniprot id: A0A1P9WTQ6
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS10610
gene id: 1178516:AWR27_RS10610
uniprot id: A0A1P9WWH5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1178516:AWR27 RS04775
gene id: 1178516:AWR27_RS04775
uniprot id: A0A1P9WTP8
names: Similarity
messages: Belongs to the sigma-54 factor family.

1178516:AWR27 RS08590
gene id: 1178516:AWR27_RS08590
uniprot id: A0A1P9WVE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS09620
gene id: 1178516:AWR27_RS09620
uniprot id: A0A1P9WVY2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1178516:AWR27 RS15945
gene id: 1178516:AWR27_RS15945
uniprot id: A0A1P9WZA6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS02735
gene id: 1178516:AWR27_RS02735
uniprot id: A0A1P9WSJ4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1178516:AWR27 RS18785
gene id: 1178516:AWR27_RS18785
uniprot id: A0A1P9X0I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1178516:AWR27 RS17235
gene id: 1178516:AWR27_RS17235
uniprot id: A0A1P9WZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1178516:AWR27 RS09270
gene id: 1178516:AWR27_RS09270
uniprot id: A0A1P9WVX8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS15950
gene id: 1178516:AWR27_RS15950
uniprot id: A0A1P9WZ55
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1178516:AWR27 RS00995
gene id: 1178516:AWR27_RS00995
uniprot id: A0A1P9WRQ5
names: Subcellular Location Annotation
messages: Cytoplasm

1178516:AWR27 RS21355
gene id: 1178516:AWR27_RS21355
uniprot id: A0A1P9X1X0
names: Subcellular Location Annotation
messages: Cell inner membrane

1178516:AWR27 RS17300
gene id: 1178516:AWR27_RS17300
uniprot id: A0A1P9WZS7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1178516:AWR27 RS02325
gene id: 1178516:AWR27_RS02325
uniprot id: A0A1P9WSA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS24710
gene id: 1178516:AWR27_RS24710
uniprot id: A0A1P9X3H1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1178516:AWR27 RS16765
gene id: 1178516:AWR27_RS16765
uniprot id: A0A1P9WZL2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1178516:AWR27 RS06330
gene id: 1178516:AWR27_RS06330
uniprot id: A0A1P9WUD1
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS11600
gene id: 1178516:AWR27_RS11600
uniprot id: A0A1P9WWZ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS13760
gene id: 1178516:AWR27_RS13760
uniprot id: A0A1P9WY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

1178516:AWR27 RS05340
gene id: 1178516:AWR27_RS05340
uniprot id: A0A1P9WTZ0
names: Similarity
messages: Belongs to the threonine aldolase family.

1178516:AWR27 RS16560
gene id: 1178516:AWR27_RS16560
uniprot id: A0A1P9WZF0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1178516:AWR27 RS22380
gene id: 1178516:AWR27_RS22380
uniprot id: A0A1P9X2C8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1178516:AWR27 RS18340
gene id: 1178516:AWR27_RS18340
uniprot id: A0A1P9X0A7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS24590
gene id: 1178516:AWR27_RS24590
uniprot id: A0A1P9X3G4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS10900
gene id: 1178516:AWR27_RS10900
uniprot id: A0A1P9WWK5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1178516:AWR27 RS01380
gene id: 1178516:AWR27_RS01380
uniprot id: A0A1P9X3Q7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1178516:AWR27 RS22725
gene id: 1178516:AWR27_RS22725
uniprot id: A0A1P9X4U9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1178516:AWR27 RS13345
gene id: 1178516:AWR27_RS13345
uniprot id: A0A1P9WXT9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS02885
gene id: 1178516:AWR27_RS02885
uniprot id: A0A1P9WSN9
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1178516:AWR27 RS06785
gene id: 1178516:AWR27_RS06785
uniprot id: A0A1P9WUI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1178516:AWR27 RS19035
gene id: 1178516:AWR27_RS19035
uniprot id: A0A1P9X0P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS21895
gene id: 1178516:AWR27_RS21895
uniprot id: A0A1P9X227
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS04930
gene id: 1178516:AWR27_RS04930
uniprot id: A0A1P9WTM4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1178516:AWR27 RS11875
gene id: 1178516:AWR27_RS11875
uniprot id: A0A1P9WX47
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1178516:AWR27 RS16915
gene id: 1178516:AWR27_RS16915
uniprot id: A0A1P9WZL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS16640
gene id: 1178516:AWR27_RS16640
uniprot id: A0A1P9WZJ2
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS00830
gene id: 1178516:AWR27_RS00830
uniprot id: A0A1P9WRP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS09680
gene id: 1178516:AWR27_RS09680
uniprot id: A0A1P9WVZ6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1178516:AWR27 RS18740
gene id: 1178516:AWR27_RS18740
uniprot id: A0A1P9X0N4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1178516:AWR27 RS20365
gene id: 1178516:AWR27_RS20365
uniprot id: A0A1P9X1F1
names: Similarity
messages: Belongs to the pirin family.

1178516:AWR27 RS17360
gene id: 1178516:AWR27_RS17360
uniprot id: A0A1P9WZV2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1178516:AWR27 RS10605
gene id: 1178516:AWR27_RS10605
uniprot id: A0A1P9WWK8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1178516:AWR27 RS02800
gene id: 1178516:AWR27_RS02800
uniprot id: A0A1P9WSN8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS14785
gene id: 1178516:AWR27_RS14785
uniprot id: A0A1P9WYJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1178516:AWR27 RS23610
gene id: 1178516:AWR27_RS23610
uniprot id: A0A1P9X300
names: Similarity
messages: Belongs to the peptidase C59 family.

1178516:AWR27 RS23020
gene id: 1178516:AWR27_RS23020
uniprot id: A0A1P9X4W9
names: Similarity
messages: Belongs to the Nth/MutY family.

1178516:AWR27 RS03220
gene id: 1178516:AWR27_RS03220
uniprot id: A0A1P9WSS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1178516:AWR27 RS22960
gene id: 1178516:AWR27_RS22960
uniprot id: A0A1P9X2L5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS09100
gene id: 1178516:AWR27_RS09100
uniprot id: A0A1P9WVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1178516:AWR27 RS24940
gene id: 1178516:AWR27_RS24940
uniprot id: A0A1P9X3P1
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS06850
gene id: 1178516:AWR27_RS06850
uniprot id: A0A1P9WUN9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS03520
gene id: 1178516:AWR27_RS03520
uniprot id: A0A1P9WSZ6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1178516:AWR27 RS07195
gene id: 1178516:AWR27_RS07195
uniprot id: A0A1P9WUP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS24885
gene id: 1178516:AWR27_RS24885
uniprot id: A0A1P9X3N1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1178516:AWR27 RS06535
gene id: 1178516:AWR27_RS06535
uniprot id: A0A1P9WUI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1178516:AWR27 RS23690
gene id: 1178516:AWR27_RS23690
uniprot id: A0A1P9X2Z0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1178516:AWR27 RS19210
gene id: 1178516:AWR27_RS19210
uniprot id: A0A1P9X0Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1178516:AWR27 RS14265
gene id: 1178516:AWR27_RS14265
uniprot id: A0A1P9WYF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS03415
gene id: 1178516:AWR27_RS03415
uniprot id: A0A1P9WST9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1178516:AWR27 RS09750
gene id: 1178516:AWR27_RS09750
uniprot id: A0A1P9WW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1178516:AWR27 RS03505
gene id: 1178516:AWR27_RS03505
uniprot id: A0A1P9WSX1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1178516:AWR27 RS24655
gene id: 1178516:AWR27_RS24655
uniprot id: A0A1P9X3G3
names: Similarity
messages: Belongs to the CarB family.

1178516:AWR27 RS17655
gene id: 1178516:AWR27_RS17655
uniprot id: A0A1P9X045
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS23705
gene id: 1178516:AWR27_RS23705
uniprot id: A0A1P9X303
names: Similarity
messages: Belongs to the ComB family.

1178516:AWR27 RS22790
gene id: 1178516:AWR27_RS22790
uniprot id: A0A1P9X2I8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS11305
gene id: 1178516:AWR27_RS11305
uniprot id: A0A1P9WWT5
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS10515
gene id: 1178516:AWR27_RS10515
uniprot id: A0A1P9WWG5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1178516:AWR27 RS18645
gene id: 1178516:AWR27_RS18645
uniprot id: A0A1P9X0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1178516:AWR27 RS12745
gene id: 1178516:AWR27_RS12745
uniprot id: A0A1P9WXH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1178516:AWR27 RS07670
gene id: 1178516:AWR27_RS07670
uniprot id: A0A1P9WUZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1178516:AWR27 RS01425
gene id: 1178516:AWR27_RS01425
uniprot id: A0A1P9WRY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1178516:AWR27 RS04870
gene id: 1178516:AWR27_RS04870
uniprot id: A0A1P9WTL4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS23520
gene id: 1178516:AWR27_RS23520
uniprot id: A0A1P9X2W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1178516:AWR27 RS03535
gene id: 1178516:AWR27_RS03535
uniprot id: A0A1P9WSZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS19690
gene id: 1178516:AWR27_RS19690
uniprot id: A0A1P9X100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1178516:AWR27 RS19780
gene id: 1178516:AWR27_RS19780
uniprot id: A0A1P9X122
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1178516:AWR27 RS06575
gene id: 1178516:AWR27_RS06575
uniprot id: A0A1P9WUF3
names: Similarity
messages: Belongs to the ribF family.

1178516:AWR27 RS23865
gene id: 1178516:AWR27_RS23865
uniprot id: A0A1P9X324
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1178516:AWR27 RS20000
gene id: 1178516:AWR27_RS20000
uniprot id: A0A1P9X150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1178516:AWR27 RS02895
gene id: 1178516:AWR27_RS02895
uniprot id: A0A1P9WSL0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1178516:AWR27 RS24275
gene id: 1178516:AWR27_RS24275
uniprot id: A0A1P9X3A6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1178516:AWR27 RS20930
gene id: 1178516:AWR27_RS20930
uniprot id: A0A1P9X1M7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS21630
gene id: 1178516:AWR27_RS21630
uniprot id: A0A1P9X216
names: Similarity
messages: Belongs to the Skp family.

1178516:AWR27 RS17400
gene id: 1178516:AWR27_RS17400
uniprot id: A0A1P9WZU4
names: Similarity
messages: Belongs to the peptidase M42 family.

1178516:AWR27 RS20885
gene id: 1178516:AWR27_RS20885
uniprot id: A0A1P9X1M3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS19490
gene id: 1178516:AWR27_RS19490
uniprot id: A0A1P9X4S1
names: Similarity
messages: Belongs to the fabD family.

1178516:AWR27 RS13355
gene id: 1178516:AWR27_RS13355
uniprot id: A0A1P9WXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS22670
gene id: 1178516:AWR27_RS22670
uniprot id: A0A1P9X2H1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1178516:AWR27 RS21260
gene id: 1178516:AWR27_RS21260
uniprot id: A0A1P9X1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS20635
gene id: 1178516:AWR27_RS20635
uniprot id: A0A1P9X1G7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1178516:AWR27 RS23410
gene id: 1178516:AWR27_RS23410
uniprot id: A0A1P9X2T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS24785
gene id: 1178516:AWR27_RS24785
uniprot id: A0A1P9X3L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1178516:AWR27 RS23210
gene id: 1178516:AWR27_RS23210
uniprot id: A0A1P9X2T1
names: Similarity
messages: Belongs to the AHA1 family.

1178516:AWR27 RS23555
gene id: 1178516:AWR27_RS23555
uniprot id: A0A1P9X2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS24130
gene id: 1178516:AWR27_RS24130
uniprot id: A0A1P9X391
names: Similarity
messages: Belongs to the Skp family.

1178516:AWR27 RS01640
gene id: 1178516:AWR27_RS01640
uniprot id: A0A1P9WS16
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS23605
gene id: 1178516:AWR27_RS23605
uniprot id: A0A1P9X2W4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS24545
gene id: 1178516:AWR27_RS24545
uniprot id: A0A1P9X568
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1178516:AWR27 RS24045
gene id: 1178516:AWR27_RS24045
uniprot id: A0A1P9X347
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS08425
gene id: 1178516:AWR27_RS08425
uniprot id: A0A1P9WVH9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1178516:AWR27 RS14055
gene id: 1178516:AWR27_RS14055
uniprot id: A0A1P9WYC4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS00320
gene id: 1178516:AWR27_RS00320
uniprot id: A0A1P9WRD4
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS14840
gene id: 1178516:AWR27_RS14840
uniprot id: A0A1P9WYK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1178516:AWR27 RS08950
gene id: 1178516:AWR27_RS08950
uniprot id: A0A1P9WVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1178516:AWR27 RS07615
gene id: 1178516:AWR27_RS07615
uniprot id: A0A1P9WV35
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS06200
gene id: 1178516:AWR27_RS06200
uniprot id: A0A1P9WU85
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1178516:AWR27 RS10480
gene id: 1178516:AWR27_RS10480
uniprot id: A0A1P9WWD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1178516:AWR27 RS07470
gene id: 1178516:AWR27_RS07470
uniprot id: A0A1P9WUV1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1178516:AWR27 RS03070
gene id: 1178516:AWR27_RS03070
uniprot id: A0A1P9WSQ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS00935
gene id: 1178516:AWR27_RS00935
uniprot id: A0A1P9WRN0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1178516:AWR27 RS16820
gene id: 1178516:AWR27_RS16820
uniprot id: A0A1P9WZN4
names: Similarity
messages: Belongs to the hyi family.

1178516:AWR27 RS18335
gene id: 1178516:AWR27_RS18335
uniprot id: A0A1P9X0A5
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS07725
gene id: 1178516:AWR27_RS07725
uniprot id: A0A1P9WUZ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1178516:AWR27 RS02010
gene id: 1178516:AWR27_RS02010
uniprot id: A0A1P9WS64
names: Similarity
messages: Belongs to the ice-binding protein family.

1178516:AWR27 RS08675
gene id: 1178516:AWR27_RS08675
uniprot id: A0A1P9WVH7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1178516:AWR27 RS15580
gene id: 1178516:AWR27_RS15580
uniprot id: A0A1P9WYY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1178516:AWR27 RS17485
gene id: 1178516:AWR27_RS17485
uniprot id: A0A1P9WZX6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS12315
gene id: 1178516:AWR27_RS12315
uniprot id: A0A1P9X487
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1178516:AWR27 RS09380
gene id: 1178516:AWR27_RS09380
uniprot id: A0A1P9WVT5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1178516:AWR27 RS07775
gene id: 1178516:AWR27_RS07775
uniprot id: A0A1P9WV65
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1178516:AWR27 RS23740
gene id: 1178516:AWR27_RS23740
uniprot id: A0A1P9X315
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1178516:AWR27 RS21445
gene id: 1178516:AWR27_RS21445
uniprot id: A0A1P9X1V7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1178516:AWR27 RS00580
gene id: 1178516:AWR27_RS00580
uniprot id: A0A1P9WRG8
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS14015
gene id: 1178516:AWR27_RS14015
uniprot id: A0A1P9WY51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1178516:AWR27 RS09000
gene id: 1178516:AWR27_RS09000
uniprot id: A0A1P9WVS7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1178516:AWR27 RS23855
gene id: 1178516:AWR27_RS23855
uniprot id: A0A1P9X358
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1178516:AWR27 RS03265
gene id: 1178516:AWR27_RS03265
uniprot id: A0A1P9WSU9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS07290
gene id: 1178516:AWR27_RS07290
uniprot id: A0A1P9WUS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1178516:AWR27 RS15400
gene id: 1178516:AWR27_RS15400
uniprot id: A0A1P9X4I4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS06795
gene id: 1178516:AWR27_RS06795
uniprot id: A0A1P9WUM9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1178516:AWR27 RS08785
gene id: 1178516:AWR27_RS08785
uniprot id: A0A1P9WVN9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1178516:AWR27 RS17660
gene id: 1178516:AWR27_RS17660
uniprot id: A0A1P9WZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS23050
gene id: 1178516:AWR27_RS23050
uniprot id: A0A1P9X2Q3
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS01590
gene id: 1178516:AWR27_RS01590
uniprot id: A0A1P9WS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1178516:AWR27 RS00160
gene id: 1178516:AWR27_RS00160
uniprot id: A0A1P9WRC0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1178516:AWR27 RS13730
gene id: 1178516:AWR27_RS13730
uniprot id: A0A1P9WY28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS16015
gene id: 1178516:AWR27_RS16015
uniprot id: A0A1P9WZ69
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS01230
gene id: 1178516:AWR27_RS01230
uniprot id: A0A1P9X3R2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1178516:AWR27 RS16590
gene id: 1178516:AWR27_RS16590
uniprot id: A0A1P9WZI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS20705
gene id: 1178516:AWR27_RS20705
uniprot id: A0A1P9X1I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1178516:AWR27 RS05970
gene id: 1178516:AWR27_RS05970
uniprot id: A0A1P9WU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1178516:AWR27 RS18030
gene id: 1178516:AWR27_RS18030
uniprot id: A0A1P9X054
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS11165
gene id: 1178516:AWR27_RS11165
uniprot id: A0A1P9WWQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS14890
gene id: 1178516:AWR27_RS14890
uniprot id: A0A1P9X4D0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS17615
gene id: 1178516:AWR27_RS17615
uniprot id: A0A1P9WZY4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1178516:AWR27 RS18350
gene id: 1178516:AWR27_RS18350
uniprot id: A0A1P9X0G3
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS05655
gene id: 1178516:AWR27_RS05655
uniprot id: A0A1P9WTX5
names: Similarity
messages: Belongs to the XseB family.

1178516:AWR27 RS20045
gene id: 1178516:AWR27_RS20045
uniprot id: A0A1P9X1B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1178516:AWR27 RS11115
gene id: 1178516:AWR27_RS11115
uniprot id: A0A1P9WWP2
names: Similarity
messages: Belongs to the SCO1/2 family.

1178516:AWR27 RS10565
gene id: 1178516:AWR27_RS10565
uniprot id: A0A1P9WWH6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1178516:AWR27 RS21920
gene id: 1178516:AWR27_RS21920
uniprot id: A0A1P9X264
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1178516:AWR27 RS19320
gene id: 1178516:AWR27_RS19320
uniprot id: A0A1P9X0T0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS09575
gene id: 1178516:AWR27_RS09575
uniprot id: A0A1P9WVY8
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1178516:AWR27 RS04520
gene id: 1178516:AWR27_RS04520
uniprot id: A0A1P9WTF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1178516:AWR27 RS11310
gene id: 1178516:AWR27_RS11310
uniprot id: A0A1P9WWW7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1178516:AWR27 RS09465
gene id: 1178516:AWR27_RS09465
uniprot id: A0A1P9WVV6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS07385
gene id: 1178516:AWR27_RS07385
uniprot id: A0A1P9WUY6
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1178516:AWR27 RS14820
gene id: 1178516:AWR27_RS14820
uniprot id: A0A1P9WYR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1178516:AWR27 RS21795
gene id: 1178516:AWR27_RS21795
uniprot id: A0A1P9X219
names: Similarity
messages: Belongs to the AIR synthase family.

1178516:AWR27 RS03390
gene id: 1178516:AWR27_RS03390
uniprot id: A0A1P9WSX3
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19805
gene id: 1178516:AWR27_RS19805
uniprot id: A0A1P9X126
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1178516:AWR27 RS17320
gene id: 1178516:AWR27_RS17320
uniprot id: A0A1P9WZW3
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1178516:AWR27 RS09635
gene id: 1178516:AWR27_RS09635
uniprot id: A0A1P9WVX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1178516:AWR27 RS24515
gene id: 1178516:AWR27_RS24515
uniprot id: A0A1P9X3E5
names: Similarity
messages: Belongs to the peptidase S9C family.

1178516:AWR27 RS24375
gene id: 1178516:AWR27_RS24375
uniprot id: A0A1P9X3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS20470
gene id: 1178516:AWR27_RS20470
uniprot id: A0A1P9X1D4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS06685
gene id: 1178516:AWR27_RS06685
uniprot id: A0A1P9WUJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS19985
gene id: 1178516:AWR27_RS19985
uniprot id: A0A1P9X191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1178516:AWR27 RS17720
gene id: 1178516:AWR27_RS17720
uniprot id: A0A1P9X005
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS18355
gene id: 1178516:AWR27_RS18355
uniprot id: A0A1P9X0B7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS11530
gene id: 1178516:AWR27_RS11530
uniprot id: A0A1P9WWY7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1178516:AWR27 RS08150
gene id: 1178516:AWR27_RS08150
uniprot id: A0A1P9WV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS14715
gene id: 1178516:AWR27_RS14715
uniprot id: A0A1P9WYI6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1178516:AWR27 RS03525
gene id: 1178516:AWR27_RS03525
uniprot id: A0A1P9X3S7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1178516:AWR27 RS16710
gene id: 1178516:AWR27_RS16710
uniprot id: A0A1P9WZK0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS08725
gene id: 1178516:AWR27_RS08725
uniprot id: A0A1P9WVI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1178516:AWR27 RS10915
gene id: 1178516:AWR27_RS10915
uniprot id: A0A1P9WWQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1178516:AWR27 RS05465
gene id: 1178516:AWR27_RS05465
uniprot id: A0A1P9X3X8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1178516:AWR27 RS09615
gene id: 1178516:AWR27_RS09615
uniprot id: A0A1P9WVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1178516:AWR27 RS19650
gene id: 1178516:AWR27_RS19650
uniprot id: A0A1P9X108
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS02850
gene id: 1178516:AWR27_RS02850
uniprot id: A0A1P9WSP7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS17430
gene id: 1178516:AWR27_RS17430
uniprot id: A0A1P9WZU6
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1178516:AWR27 RS17260
gene id: 1178516:AWR27_RS17260
uniprot id: A0A1P9WZU3
names: Similarity
messages: Belongs to the citrate synthase family.

1178516:AWR27 RS19950
gene id: 1178516:AWR27_RS19950
uniprot id: A0A1P9X142
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1178516:AWR27 RS22830
gene id: 1178516:AWR27_RS22830
uniprot id: A0A1P9X2I9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1178516:AWR27 RS21075
gene id: 1178516:AWR27_RS21075
uniprot id: A0A1P9X1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1178516:AWR27 RS01735
gene id: 1178516:AWR27_RS01735
uniprot id: A0A1P9WS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1178516:AWR27 RS22665
gene id: 1178516:AWR27_RS22665
uniprot id: A0A1P9X2H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1178516:AWR27 RS08330
gene id: 1178516:AWR27_RS08330
uniprot id: A0A1P9WVB0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1178516:AWR27 RS10785
gene id: 1178516:AWR27_RS10785
uniprot id: A0A1P9WWI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1178516:AWR27 RS01930
gene id: 1178516:AWR27_RS01930
uniprot id: A0A1P9WS67
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1178516:AWR27 RS20790
gene id: 1178516:AWR27_RS20790
uniprot id: A0A1P9X1K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1178516:AWR27 RS17900
gene id: 1178516:AWR27_RS17900
uniprot id: A0A1P9X032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS13560
gene id: 1178516:AWR27_RS13560
uniprot id: A0A1P9WXZ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS11950
gene id: 1178516:AWR27_RS11950
uniprot id: A0A1P9WX46
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1178516:AWR27 RS16450
gene id: 1178516:AWR27_RS16450
uniprot id: A0A1P9WZE8
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19335
gene id: 1178516:AWR27_RS19335
uniprot id: A0A1P9X0X0
names: Similarity
messages: Belongs to the peptidase M1 family.

1178516:AWR27 RS08815
gene id: 1178516:AWR27_RS08815
uniprot id: A0A1P9WVI1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1178516:AWR27 RS23750
gene id: 1178516:AWR27_RS23750
uniprot id: A0A1P9X331
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1178516:AWR27 RS24010
gene id: 1178516:AWR27_RS24010
uniprot id: A0A1P9X335
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1178516:AWR27 RS23745
gene id: 1178516:AWR27_RS23745
uniprot id: A0A1P9X2Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1178516:AWR27 RS00440
gene id: 1178516:AWR27_RS00440
uniprot id: A0A1P9WRF8
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1178516:AWR27 RS10995
gene id: 1178516:AWR27_RS10995
uniprot id: A0A1P9WWM5
names: Similarity
messages: Belongs to the peptidase U62 family.

1178516:AWR27 RS24805
gene id: 1178516:AWR27_RS24805
uniprot id: A0A1P9X3J7
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1178516:AWR27 RS02240
gene id: 1178516:AWR27_RS02240
uniprot id: A0A1P9WSB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1178516:AWR27 RS01780
gene id: 1178516:AWR27_RS01780
uniprot id: A0A1P9WS28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1178516:AWR27 RS19625
gene id: 1178516:AWR27_RS19625
uniprot id: A0A1P9X0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1178516:AWR27 RS21575
gene id: 1178516:AWR27_RS21575
uniprot id: A0A1P9X208
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1178516:AWR27 RS20490
gene id: 1178516:AWR27_RS20490
uniprot id: A0A1P9X1F2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1178516:AWR27 RS17960
gene id: 1178516:AWR27_RS17960
uniprot id: A0A1P9X042
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1178516:AWR27 RS07415
gene id: 1178516:AWR27_RS07415
uniprot id: A0A1P9WUV0
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS16490
gene id: 1178516:AWR27_RS16490
uniprot id: A0A1P9WZE6
names: Subcellular Location Annotation
messages: Nucleus

1178516:AWR27 RS07055
gene id: 1178516:AWR27_RS07055
uniprot id: A0A1P9WUR9
names: Similarity
messages: Belongs to the CvfB family.

1178516:AWR27 RS01055
gene id: 1178516:AWR27_RS01055
uniprot id: A0A1P9WRR5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS15295
gene id: 1178516:AWR27_RS15295
uniprot id: A0A1P9WYV6
names: Similarity
messages: Belongs to the peptidase C14A family.

1178516:AWR27 RS02690
gene id: 1178516:AWR27_RS02690
uniprot id: A0A1P9WSJ6
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1178516:AWR27 RS00735
gene id: 1178516:AWR27_RS00735
uniprot id: A0A1P9WRK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1178516:AWR27 RS14845
gene id: 1178516:AWR27_RS14845
uniprot id: A0A1P9WYN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1178516:AWR27 RS20860
gene id: 1178516:AWR27_RS20860
uniprot id: A0A1P9X1J3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1178516:AWR27 RS19015
gene id: 1178516:AWR27_RS19015
uniprot id: A0A1P9X0M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS11090
gene id: 1178516:AWR27_RS11090
uniprot id: A0A1P9WWQ1
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1178516:AWR27 RS01450
gene id: 1178516:AWR27_RS01450
uniprot id: A0A1P9WRY1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1178516:AWR27 RS10630
gene id: 1178516:AWR27_RS10630
uniprot id: A0A1P9WWH2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1178516:AWR27 RS17310
gene id: 1178516:AWR27_RS17310
uniprot id: A0A1P9WZS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

1178516:AWR27 RS11975
gene id: 1178516:AWR27_RS11975
uniprot id: A0A1P9WX70
names: Similarity
messages: Belongs to the DinB family.

1178516:AWR27 RS14855
gene id: 1178516:AWR27_RS14855
uniprot id: A0A1P9X4I9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1178516:AWR27 RS15445
gene id: 1178516:AWR27_RS15445
uniprot id: A0A1P9X4G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1178516:AWR27 RS01310
gene id: 1178516:AWR27_RS01310
uniprot id: A0A1P9WRV0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS17170
gene id: 1178516:AWR27_RS17170
uniprot id: A0A1P9WZQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1178516:AWR27 RS01835
gene id: 1178516:AWR27_RS01835
uniprot id: A0A1P9WS70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1178516:AWR27 RS24955
gene id: 1178516:AWR27_RS24955
uniprot id: A0A1P9X3N7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1178516:AWR27 RS09130
gene id: 1178516:AWR27_RS09130
uniprot id: A0A1P9WVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1178516:AWR27 RS06905
gene id: 1178516:AWR27_RS06905
uniprot id: A0A1P9WUK9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS03150
gene id: 1178516:AWR27_RS03150
uniprot id: A0A1P9WSS2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1178516:AWR27 RS02875
gene id: 1178516:AWR27_RS02875
uniprot id: A0A1P9WSM7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1178516:AWR27 RS02715
gene id: 1178516:AWR27_RS02715
uniprot id: A0A1P9WSH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1178516:AWR27 RS06585
gene id: 1178516:AWR27_RS06585
uniprot id: A0A1P9WUJ4
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1178516:AWR27 RS00140
gene id: 1178516:AWR27_RS00140
uniprot id: A0A1P9WRA5
names: Similarity
messages: Belongs to the SufE family.

1178516:AWR27 RS24680
gene id: 1178516:AWR27_RS24680
uniprot id: A0A1P9X3I6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1178516:AWR27 RS16585
gene id: 1178516:AWR27_RS16585
uniprot id: A0A1P9WZH9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS02610
gene id: 1178516:AWR27_RS02610
uniprot id: A0A1P9WSK9
names: Similarity
messages: Belongs to the LEA type 2 family.

1178516:AWR27 RS03695
gene id: 1178516:AWR27_RS03695
uniprot id: A0A1P9X3X2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS14585
gene id: 1178516:AWR27_RS14585
uniprot id: A0A1P9WYF7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS05035
gene id: 1178516:AWR27_RS05035
uniprot id: A0A1P9WTT6
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS01915
gene id: 1178516:AWR27_RS01915
uniprot id: A0A1P9WS53
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1178516:AWR27 RS05960
gene id: 1178516:AWR27_RS05960
uniprot id: A0A1P9WU47
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1178516:AWR27 RS22120
gene id: 1178516:AWR27_RS22120
uniprot id: A0A1P9X281
names: Similarity
messages: Belongs to the aspartokinase family.

1178516:AWR27 RS01805
gene id: 1178516:AWR27_RS01805
uniprot id: A0A1P9WS43
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS08475
gene id: 1178516:AWR27_RS08475
uniprot id: A0A1P9WVJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1178516:AWR27 RS01760
gene id: 1178516:AWR27_RS01760
uniprot id: A0A1P9WS39
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS10080
gene id: 1178516:AWR27_RS10080
uniprot id: A0A1P9WW57
names: Similarity
messages: Belongs to the peptidase M1 family.

1178516:AWR27 RS19580
gene id: 1178516:AWR27_RS19580
uniprot id: A0A1P9X0X9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1178516:AWR27 RS21410
gene id: 1178516:AWR27_RS21410
uniprot id: A0A1P9X1U3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS06185
gene id: 1178516:AWR27_RS06185
uniprot id: A0A1P9WU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS02400
gene id: 1178516:AWR27_RS02400
uniprot id: A0A1P9WSF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS11245
gene id: 1178516:AWR27_RS11245
uniprot id: A0A1P9WWS9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS23030
gene id: 1178516:AWR27_RS23030
uniprot id: A0A1P9X2M7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19450
gene id: 1178516:AWR27_RS19450
uniprot id: A0A1P9X0V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS02995
gene id: 1178516:AWR27_RS02995
uniprot id: A0A1P9WSP1
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19835
gene id: 1178516:AWR27_RS19835
uniprot id: A0A1P9X133
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1178516:AWR27 RS20290
gene id: 1178516:AWR27_RS20290
uniprot id: A0A1P9X1F3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1178516:AWR27 RS24240
gene id: 1178516:AWR27_RS24240
uniprot id: A0A1P9X386
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS11745
gene id: 1178516:AWR27_RS11745
uniprot id: A0A1P9WX07
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS12345
gene id: 1178516:AWR27_RS12345
uniprot id: A0A1P9WX96
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1178516:AWR27 RS09925
gene id: 1178516:AWR27_RS09925
uniprot id: A0A1P9WWA6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1178516:AWR27 RS11160
gene id: 1178516:AWR27_RS11160
uniprot id: A0A1P9WWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS05915
gene id: 1178516:AWR27_RS05915
uniprot id: A0A1P9WU26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS19080
gene id: 1178516:AWR27_RS19080
uniprot id: A0A1P9X0T2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1178516:AWR27 RS24120
gene id: 1178516:AWR27_RS24120
uniprot id: A0A1P9X378
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1178516:AWR27 RS09740
gene id: 1178516:AWR27_RS09740
uniprot id: A0A1P9WVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS21880
gene id: 1178516:AWR27_RS21880
uniprot id: A0A1P9X234
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1178516:AWR27 RS22010
gene id: 1178516:AWR27_RS22010
uniprot id: A0A1P9X240
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1178516:AWR27 RS15805
gene id: 1178516:AWR27_RS15805
uniprot id: A0A1P9WZ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS11110
gene id: 1178516:AWR27_RS11110
uniprot id: A0A1P9WWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1178516:AWR27 RS20750
gene id: 1178516:AWR27_RS20750
uniprot id: A0A1P9X1H9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS16340
gene id: 1178516:AWR27_RS16340
uniprot id: A0A1P9WZC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1178516:AWR27 RS21150
gene id: 1178516:AWR27_RS21150
uniprot id: A0A1P9X1S2
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS06750
gene id: 1178516:AWR27_RS06750
uniprot id: A0A1P9WUM2
names: Similarity
messages: Belongs to the YoeB family.

1178516:AWR27 RS11395
gene id: 1178516:AWR27_RS11395
uniprot id: A0A1P9WWU7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1178516:AWR27 RS05250
gene id: 1178516:AWR27_RS05250
uniprot id: A0A1P9WTV4
names: Similarity
messages: Belongs to the UPF0175 family.

1178516:AWR27 RS05625
gene id: 1178516:AWR27_RS05625
uniprot id: A0A1P9WTY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1178516:AWR27 RS07945
gene id: 1178516:AWR27_RS07945
uniprot id: A0A1P9WV94
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1178516:AWR27 RS12310
gene id: 1178516:AWR27_RS12310
uniprot id: A0A1P9WXI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1178516:AWR27 RS18965
gene id: 1178516:AWR27_RS18965
uniprot id: A0A1P9X0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1178516:AWR27 RS06835
gene id: 1178516:AWR27_RS06835
uniprot id: A0A1P9WUI6
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS09715
gene id: 1178516:AWR27_RS09715
uniprot id: A0A1P9WW16
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1178516:AWR27 RS19600
gene id: 1178516:AWR27_RS19600
uniprot id: A0A1P9X0Z7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS22350
gene id: 1178516:AWR27_RS22350
uniprot id: A0A1P9X2B0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1178516:AWR27 RS14195
gene id: 1178516:AWR27_RS14195
uniprot id: A0A1P9WYA7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1178516:AWR27 RS09315
gene id: 1178516:AWR27_RS09315
uniprot id: A0A1P9WVS2
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS18140
gene id: 1178516:AWR27_RS18140
uniprot id: A0A1P9X4J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1178516:AWR27 RS11845
gene id: 1178516:AWR27_RS11845
uniprot id: A0A1P9WX23
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1178516:AWR27 RS02975
gene id: 1178516:AWR27_RS02975
uniprot id: A0A1P9WSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1178516:AWR27 RS03350
gene id: 1178516:AWR27_RS03350
uniprot id: A0A1P9WSU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1178516:AWR27 RS13050
gene id: 1178516:AWR27_RS13050
uniprot id: A0A1P9WXN4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS13965
gene id: 1178516:AWR27_RS13965
uniprot id: A0A1P9WY71
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1178516:AWR27 RS16080
gene id: 1178516:AWR27_RS16080
uniprot id: A0A1P9X4E7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1178516:AWR27 RS06490
gene id: 1178516:AWR27_RS06490
uniprot id: A0A1P9X3Y2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS23665
gene id: 1178516:AWR27_RS23665
uniprot id: A0A1P9X2Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1178516:AWR27 RS07080
gene id: 1178516:AWR27_RS07080
uniprot id: A0A1P9WUN4
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS19280
gene id: 1178516:AWR27_RS19280
uniprot id: A0A1P9X0S9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1178516:AWR27 RS05155
gene id: 1178516:AWR27_RS05155
uniprot id: A0A1P9WTR0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS11130
gene id: 1178516:AWR27_RS11130
uniprot id: A0A1P9WWW1
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1178516:AWR27 RS00600
gene id: 1178516:AWR27_RS00600
uniprot id: A0A1P9WRI4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS05540
gene id: 1178516:AWR27_RS05540
uniprot id: A0A1P9WTW0
names: Similarity
messages: Belongs to the sulfatase family.

1178516:AWR27 RS05045
gene id: 1178516:AWR27_RS05045
uniprot id: A0A1P9WTN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1178516:AWR27 RS07325
gene id: 1178516:AWR27_RS07325
uniprot id: A0A1P9WUX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1178516:AWR27 RS07825
gene id: 1178516:AWR27_RS07825
uniprot id: A0A1P9WV74
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1178516:AWR27 RS24200
gene id: 1178516:AWR27_RS24200
uniprot id: A0A1P9X369
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1178516:AWR27 RS17155
gene id: 1178516:AWR27_RS17155
uniprot id: A0A1P9WZV4
names: Function
messages: May be involved in the biogenesis of curli organelles.

1178516:AWR27 RS19440
gene id: 1178516:AWR27_RS19440
uniprot id: A0A1P9X0W6
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS12325
gene id: 1178516:AWR27_RS12325
uniprot id: A0A1P9WXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS24750
gene id: 1178516:AWR27_RS24750
uniprot id: A0A1P9X4Z0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1178516:AWR27 RS18735
gene id: 1178516:AWR27_RS18735
uniprot id: A0A1P9X0K3
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS12920
gene id: 1178516:AWR27_RS12920
uniprot id: A0A1P9WXJ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS08380
gene id: 1178516:AWR27_RS08380
uniprot id: A0A1P9WVC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1178516:AWR27 RS19965
gene id: 1178516:AWR27_RS19965
uniprot id: A0A1P9X152
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS13415
gene id: 1178516:AWR27_RS13415
uniprot id: A0A1P9WXU1
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1178516:AWR27 RS22795
gene id: 1178516:AWR27_RS22795
uniprot id: A0A1P9X2L4
names: Similarity
messages: Belongs to the sterol desaturase family.

1178516:AWR27 RS10830
gene id: 1178516:AWR27_RS10830
uniprot id: A0A1P9WWJ8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1178516:AWR27 RS18285
gene id: 1178516:AWR27_RS18285
uniprot id: A0A1P9X096
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1178516:AWR27 RS22950
gene id: 1178516:AWR27_RS22950
uniprot id: A0A1P9X2P0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1178516:AWR27 RS11930
gene id: 1178516:AWR27_RS11930
uniprot id: A0A1P9WX78
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS15495
gene id: 1178516:AWR27_RS15495
uniprot id: A0A1P9WYX2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1178516:AWR27 RS21930
gene id: 1178516:AWR27_RS21930
uniprot id: A0A1P9X243
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1178516:AWR27 RS23775
gene id: 1178516:AWR27_RS23775
uniprot id: A0A1P9X2Z5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1178516:AWR27 RS24565
gene id: 1178516:AWR27_RS24565
uniprot id: A0A1P9X3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1178516:AWR27 RS13670
gene id: 1178516:AWR27_RS13670
uniprot id: A0A1P9WY19
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1178516:AWR27 RS23925
gene id: 1178516:AWR27_RS23925
uniprot id: A0A1P9X334
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1178516:AWR27 RS02260
gene id: 1178516:AWR27_RS02260
uniprot id: A0A1P9WSA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1178516:AWR27 RS04815
gene id: 1178516:AWR27_RS04815
uniprot id: A0A1P9WTK7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1178516:AWR27 RS13860
gene id: 1178516:AWR27_RS13860
uniprot id: A0A1P9WY54
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS18995
gene id: 1178516:AWR27_RS18995
uniprot id: A0A1P9X0M2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1178516:AWR27 RS20055
gene id: 1178516:AWR27_RS20055
uniprot id: A0A1P9X179
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS19045
gene id: 1178516:AWR27_RS19045
uniprot id: A0A1P9X0N2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1178516:AWR27 RS24890
gene id: 1178516:AWR27_RS24890
uniprot id: A0A1P9X3J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1178516:AWR27 RS12210
gene id: 1178516:AWR27_RS12210
uniprot id: A0A1P9WX81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS06515
gene id: 1178516:AWR27_RS06515
uniprot id: A0A1P9WUE3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS02085
gene id: 1178516:AWR27_RS02085
uniprot id: A0A1P9WS90
names: Similarity
messages: Belongs to the asparagine synthetase family.

1178516:AWR27 RS02330
gene id: 1178516:AWR27_RS02330
uniprot id: A0A1P9WSB9
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS07025
gene id: 1178516:AWR27_RS07025
uniprot id: A0A1P9WUL6
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS04415
gene id: 1178516:AWR27_RS04415
uniprot id: A0A1P9WTH1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS17125
gene id: 1178516:AWR27_RS17125
uniprot id: A0A1P9WZP8
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1178516:AWR27 RS17470
gene id: 1178516:AWR27_RS17470
uniprot id: A0A1P9WZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1178516:AWR27 RS17350
gene id: 1178516:AWR27_RS17350
uniprot id: A0A1P9WZX7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS07935
gene id: 1178516:AWR27_RS07935
uniprot id: A0A1P9WV97
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1178516:AWR27 RS04965
gene id: 1178516:AWR27_RS04965
uniprot id: A0A1P9X3V8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1178516:AWR27 RS21670
gene id: 1178516:AWR27_RS21670
uniprot id: A0A1P9X1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS01235
gene id: 1178516:AWR27_RS01235
uniprot id: A0A1P9WRU7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS09180
gene id: 1178516:AWR27_RS09180
uniprot id: A0A1P9WVR6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1178516:AWR27 RS22615
gene id: 1178516:AWR27_RS22615
uniprot id: A0A1P9X2G5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1178516:AWR27 RS00275
gene id: 1178516:AWR27_RS00275
uniprot id: A0A1P9WRD7
names: Similarity
messages: Belongs to the DtxR/MntR family.

1178516:AWR27 RS03245
gene id: 1178516:AWR27_RS03245
uniprot id: A0A1P9WSR0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1178516:AWR27 RS18670
gene id: 1178516:AWR27_RS18670
uniprot id: A0A1P9X4R0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1178516:AWR27 RS22805
gene id: 1178516:AWR27_RS22805
uniprot id: A0A1P9X2N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS12320
gene id: 1178516:AWR27_RS12320
uniprot id: A0A1P9WXD0
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

1178516:AWR27 RS19020
gene id: 1178516:AWR27_RS19020
uniprot id: A0A1P9X0M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS00100
gene id: 1178516:AWR27_RS00100
uniprot id: A0A1P9WRA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1178516:AWR27 RS11775
gene id: 1178516:AWR27_RS11775
uniprot id: A0A1P9WX22
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1178516:AWR27 RS12425
gene id: 1178516:AWR27_RS12425
uniprot id: A0A1P9WXC8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1178516:AWR27 RS20475
gene id: 1178516:AWR27_RS20475
uniprot id: A0A1P9X1F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1178516:AWR27 RS12665
gene id: 1178516:AWR27_RS12665
uniprot id: A0A1P9WXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1178516:AWR27 RS24450
gene id: 1178516:AWR27_RS24450
uniprot id: A0A1P9X3D6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS14345
gene id: 1178516:AWR27_RS14345
uniprot id: A0A1P9WYE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1178516:AWR27 RS08395
gene id: 1178516:AWR27_RS08395
uniprot id: A0A1P9WVC2
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS20105
gene id: 1178516:AWR27_RS20105
uniprot id: A0A1P9X4M6
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS09090
gene id: 1178516:AWR27_RS09090
uniprot id: A0A1P9WVN5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1178516:AWR27 RS03295
gene id: 1178516:AWR27_RS03295
uniprot id: A0A1P9WST3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1178516:AWR27 RS20370
gene id: 1178516:AWR27_RS20370
uniprot id: A0A1P9X1B9
names: Similarity
messages: Belongs to the FPG family.

1178516:AWR27 RS20990
gene id: 1178516:AWR27_RS20990
uniprot id: A0A1P9X1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1178516:AWR27 RS20555
gene id: 1178516:AWR27_RS20555
uniprot id: A0A1P9X1G4
names: Similarity
messages: Belongs to the threonine synthase family.

1178516:AWR27 RS10850
gene id: 1178516:AWR27_RS10850
uniprot id: A0A1P9WWJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1178516:AWR27 RS05375
gene id: 1178516:AWR27_RS05375
uniprot id: A0A1P9X403
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1178516:AWR27 RS00260
gene id: 1178516:AWR27_RS00260
uniprot id: A0A1P9X3M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1178516:AWR27 RS17080
gene id: 1178516:AWR27_RS17080
uniprot id: A0A1P9WZQ2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1178516:AWR27 RS06280
gene id: 1178516:AWR27_RS06280
uniprot id: A0A1P9WUC3
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS03935
gene id: 1178516:AWR27_RS03935
uniprot id: A0A1P9WTA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1178516:AWR27 RS22520
gene id: 1178516:AWR27_RS22520
uniprot id: A0A1P9X2I6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS18070
gene id: 1178516:AWR27_RS18070
uniprot id: A0A1P9X0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1178516:AWR27 RS08805
gene id: 1178516:AWR27_RS08805
uniprot id: A0A1P9WVI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1178516:AWR27 RS08760
gene id: 1178516:AWR27_RS08760
uniprot id: A0A1P9WVH6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1178516:AWR27 RS02315
gene id: 1178516:AWR27_RS02315
uniprot id: A0A1P9WSF6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS06595
gene id: 1178516:AWR27_RS06595
uniprot id: A0A1P9WUF2
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS13990
gene id: 1178516:AWR27_RS13990
uniprot id: A0A1P9X4F2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1178516:AWR27 RS07820
gene id: 1178516:AWR27_RS07820
uniprot id: A0A1P9WV25
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS13595
gene id: 1178516:AWR27_RS13595
uniprot id: A0A1P9WXX6
names: Similarity
messages: Belongs to the peptidase S41A family.

1178516:AWR27 RS19430
gene id: 1178516:AWR27_RS19430
uniprot id: A0A1P9X101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS20825
gene id: 1178516:AWR27_RS20825
uniprot id: A0A1P9X1I5
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS17825
gene id: 1178516:AWR27_RS17825
uniprot id: A0A1P9X075
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS08430
gene id: 1178516:AWR27_RS08430
uniprot id: A0A1P9WVD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1178516:AWR27 RS12850
gene id: 1178516:AWR27_RS12850
uniprot id: A0A1P9X496
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1178516:AWR27 RS24380
gene id: 1178516:AWR27_RS24380
uniprot id: A0A1P9X3A0
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS19065
gene id: 1178516:AWR27_RS19065
uniprot id: A0A1P9X0N9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS01515
gene id: 1178516:AWR27_RS01515
uniprot id: A0A1P9WRZ1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1178516:AWR27 RS24360
gene id: 1178516:AWR27_RS24360
uniprot id: A0A1P9X3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS13925
gene id: 1178516:AWR27_RS13925
uniprot id: A0A1P9WY30
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS23185
gene id: 1178516:AWR27_RS23185
uniprot id: A0A1P9X547
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1178516:AWR27 RS09780
gene id: 1178516:AWR27_RS09780
uniprot id: A0A1P9WW14
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS11145
gene id: 1178516:AWR27_RS11145
uniprot id: A0A1P9WWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1178516:AWR27 RS22965
gene id: 1178516:AWR27_RS22965
uniprot id: A0A1P9X2M4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1178516:AWR27 RS22475
gene id: 1178516:AWR27_RS22475
uniprot id: A0A1P9X2C2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1178516:AWR27 RS15080
gene id: 1178516:AWR27_RS15080
uniprot id: A0A1P9WYS5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS05645
gene id: 1178516:AWR27_RS05645
uniprot id: A0A1P9WTZ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS11415
gene id: 1178516:AWR27_RS11415
uniprot id: A0A1P9WWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

1178516:AWR27 RS00370
gene id: 1178516:AWR27_RS00370
uniprot id: A0A1P9WRE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1178516:AWR27 RS23285
gene id: 1178516:AWR27_RS23285
uniprot id: A0A1P9X2Q6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1178516:AWR27 RS21595
gene id: 1178516:AWR27_RS21595
uniprot id: A0A1P9X1W7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1178516:AWR27 RS12375
gene id: 1178516:AWR27_RS12375
uniprot id: A0A1P9WXB2
names: Similarity
messages: Belongs to the peptidase C40 family.

1178516:AWR27 RS18970
gene id: 1178516:AWR27_RS18970
uniprot id: A0A1P9X0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1178516:AWR27 RS14480
gene id: 1178516:AWR27_RS14480
uniprot id: A0A1P9WYD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1178516:AWR27 RS21570
gene id: 1178516:AWR27_RS21570
uniprot id: A0A1P9X1Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1178516:AWR27 RS11180
gene id: 1178516:AWR27_RS11180
uniprot id: A0A1P9WWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS12215
gene id: 1178516:AWR27_RS12215
uniprot id: A0A1P9WXD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS19350
gene id: 1178516:AWR27_RS19350
uniprot id: A0A1P9X0T9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1178516:AWR27 RS03185
gene id: 1178516:AWR27_RS03185
uniprot id: A0A1P9WSS0
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1178516:AWR27 RS08065
gene id: 1178516:AWR27_RS08065
uniprot id: A0A1P9WV47
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS16465
gene id: 1178516:AWR27_RS16465
uniprot id: A0A1P9WZG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1178516:AWR27 RS23170
gene id: 1178516:AWR27_RS23170
uniprot id: A0A1P9X2P3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1178516:AWR27 RS01890
gene id: 1178516:AWR27_RS01890
uniprot id: A0A1P9WS78
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS18445
gene id: 1178516:AWR27_RS18445
uniprot id: A0A1P9X0C4
names: Subcellular Location Annotation
messages: Cytoplasm

1178516:AWR27 RS10680
gene id: 1178516:AWR27_RS10680
uniprot id: A0A1P9WWL7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1178516:AWR27 RS16470
gene id: 1178516:AWR27_RS16470
uniprot id: A0A1P9WZG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1178516:AWR27 RS13910
gene id: 1178516:AWR27_RS13910
uniprot id: A0A1P9WY67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1178516:AWR27 RS23870
gene id: 1178516:AWR27_RS23870
uniprot id: A0A1P9X353
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1178516:AWR27 RS01000
gene id: 1178516:AWR27_RS01000
uniprot id: A0A1P9WRQ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS22020
gene id: 1178516:AWR27_RS22020
uniprot id: A0A1P9X241
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1178516:AWR27 RS22100
gene id: 1178516:AWR27_RS22100
uniprot id: A0A1P9X261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS21140
gene id: 1178516:AWR27_RS21140
uniprot id: A0A1P9X1T7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1178516:AWR27 RS20855
gene id: 1178516:AWR27_RS20855
uniprot id: A0A1P9X1K4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1178516:AWR27 RS13630
gene id: 1178516:AWR27_RS13630
uniprot id: A0A1P9WY17
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1178516:AWR27 RS20965
gene id: 1178516:AWR27_RS20965
uniprot id: A0A1P9X1N1
names: Similarity
messages: Belongs to the FMO family.

1178516:AWR27 RS12290
gene id: 1178516:AWR27_RS12290
uniprot id: A0A1P9WXB0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1178516:AWR27 RS18790
gene id: 1178516:AWR27_RS18790
uniprot id: A0A1P9X0L5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS00435
gene id: 1178516:AWR27_RS00435
uniprot id: A0A1P9WRF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS14680
gene id: 1178516:AWR27_RS14680
uniprot id: A0A1P9WYK0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1178516:AWR27 RS19815
gene id: 1178516:AWR27_RS19815
uniprot id: A0A1P9X165
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1178516:AWR27 RS08565
gene id: 1178516:AWR27_RS08565
uniprot id: A0A1P9WVF5
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS22715
gene id: 1178516:AWR27_RS22715
uniprot id: A0A1P9X2I5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1178516:AWR27 RS01325
gene id: 1178516:AWR27_RS01325
uniprot id: A0A1P9WRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1178516:AWR27 RS08435
gene id: 1178516:AWR27_RS08435
uniprot id: A0A1P9WVB3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1178516:AWR27 RS08925
gene id: 1178516:AWR27_RS08925
uniprot id: A0A1P9WVK0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS18325
gene id: 1178516:AWR27_RS18325
uniprot id: A0A1P9X0B1
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19590
gene id: 1178516:AWR27_RS19590
uniprot id: A0A1P9X124
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1178516:AWR27 RS19895
gene id: 1178516:AWR27_RS19895
uniprot id: A0A1P9X170
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1178516:AWR27 RS01075
gene id: 1178516:AWR27_RS01075
uniprot id: A0A1P9WRS8
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS13660
gene id: 1178516:AWR27_RS13660
uniprot id: A0A1P9WY50
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1178516:AWR27 RS04540
gene id: 1178516:AWR27_RS04540
uniprot id: A0A1P9WTE8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1178516:AWR27 RS11015
gene id: 1178516:AWR27_RS11015
uniprot id: A0A1P9WWN1
names: Similarity
messages: Belongs to the peptidase U62 family.

1178516:AWR27 RS14865
gene id: 1178516:AWR27_RS14865
uniprot id: A0A1P9WYL0
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1178516:AWR27 RS22190
gene id: 1178516:AWR27_RS22190
uniprot id: A0A1P9X275
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS08335
gene id: 1178516:AWR27_RS08335
uniprot id: A0A1P9WVA1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1178516:AWR27 RS04770
gene id: 1178516:AWR27_RS04770
uniprot id: A0A1P9WTK6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1178516:AWR27 RS00490
gene id: 1178516:AWR27_RS00490
uniprot id: A0A1P9WRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1178516:AWR27 RS12510
gene id: 1178516:AWR27_RS12510
uniprot id: A0A1P9WXD3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1178516:AWR27 RS03985
gene id: 1178516:AWR27_RS03985
uniprot id: A0A1P9X3V9
names: Similarity
messages: Belongs to the histone deacetylase family.

1178516:AWR27 RS24895
gene id: 1178516:AWR27_RS24895
uniprot id: A0A1P9X3M2
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS09260
gene id: 1178516:AWR27_RS09260
uniprot id: A0A1P9WVR0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1178516:AWR27 RS12845
gene id: 1178516:AWR27_RS12845
uniprot id: A0A1P9WXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1178516:AWR27 RS08170
gene id: 1178516:AWR27_RS08170
uniprot id: A0A1P9WVD3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1178516:AWR27 RS11440
gene id: 1178516:AWR27_RS11440
uniprot id: A0A1P9X481
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1178516:AWR27 RS19900
gene id: 1178516:AWR27_RS19900
uniprot id: A0A1P9X139
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1178516:AWR27 RS07665
gene id: 1178516:AWR27_RS07665
uniprot id: A0A1P9WV44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1178516:AWR27 RS01245
gene id: 1178516:AWR27_RS01245
uniprot id: A0A1P9WRW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1178516:AWR27 RS04610
gene id: 1178516:AWR27_RS04610
uniprot id: A0A1P9WTM1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1178516:AWR27 RS05025
gene id: 1178516:AWR27_RS05025
uniprot id: A0A1P9WTN8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1178516:AWR27 RS12170
gene id: 1178516:AWR27_RS12170
uniprot id: A0A1P9WX92
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS22250
gene id: 1178516:AWR27_RS22250
uniprot id: A0A1P9X4S8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1178516:AWR27 RS17800
gene id: 1178516:AWR27_RS17800
uniprot id: A0A1P9X4I7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1178516:AWR27 RS23195
gene id: 1178516:AWR27_RS23195
uniprot id: A0A1P9X2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1178516:AWR27 RS18500
gene id: 1178516:AWR27_RS18500
uniprot id: A0A1P9X0G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS03080
gene id: 1178516:AWR27_RS03080
uniprot id: A0A1P9WSP9
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1178516:AWR27 RS12865
gene id: 1178516:AWR27_RS12865
uniprot id: A0A1P9WXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS11970
gene id: 1178516:AWR27_RS11970
uniprot id: A0A1P9WXB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1178516:AWR27 RS17365
gene id: 1178516:AWR27_RS17365
uniprot id: A0A1P9WZT5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1178516:AWR27 RS19745
gene id: 1178516:AWR27_RS19745
uniprot id: A0A1P9X117
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS15910
gene id: 1178516:AWR27_RS15910
uniprot id: A0A1P9WZ39
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1178516:AWR27 RS10220
gene id: 1178516:AWR27_RS10220
uniprot id: A0A1P9WW89
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1178516:AWR27 RS08705
gene id: 1178516:AWR27_RS08705
uniprot id: A0A1P9WVG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1178516:AWR27 RS17925
gene id: 1178516:AWR27_RS17925
uniprot id: A0A1P9X043
names: Similarity
messages: Belongs to the peptidase S58 family.

1178516:AWR27 RS23920
gene id: 1178516:AWR27_RS23920
uniprot id: A0A1P9X328
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1178516:AWR27 RS20040
gene id: 1178516:AWR27_RS20040
uniprot id: A0A1P9X176
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1178516:AWR27 RS01015
gene id: 1178516:AWR27_RS01015
uniprot id: A0A1P9WRQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS04255
gene id: 1178516:AWR27_RS04255
uniprot id: A0A1P9WTB6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1178516:AWR27 RS06060
gene id: 1178516:AWR27_RS06060
uniprot id: A0A1P9WU63
names: Similarity
messages: Belongs to the HypE family.

1178516:AWR27 RS21365
gene id: 1178516:AWR27_RS21365
uniprot id: A0A1P9X1X4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS21915
gene id: 1178516:AWR27_RS21915
uniprot id: A0A1P9X236
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1178516:AWR27 RS19395
gene id: 1178516:AWR27_RS19395
uniprot id: A0A1P9X0V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1178516:AWR27 RS08750
gene id: 1178516:AWR27_RS08750
uniprot id: A0A1P9WVI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1178516:AWR27 RS09745
gene id: 1178516:AWR27_RS09745
uniprot id: A0A1P9WW09
names: Similarity
messages: Belongs to the DapA family.

1178516:AWR27 RS09655
gene id: 1178516:AWR27_RS09655
uniprot id: A0A1P9WVZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1178516:AWR27 RS04825
gene id: 1178516:AWR27_RS04825
uniprot id: A0A1P9WTK2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1178516:AWR27 RS05140
gene id: 1178516:AWR27_RS05140
uniprot id: A0A1P9WTP9
names: Similarity
messages: Belongs to the YciI family.

1178516:AWR27 RS22560
gene id: 1178516:AWR27_RS22560
uniprot id: A0A1P9X2F1
names: Subcellular Location Annotation
messages: Cytoplasm

1178516:AWR27 RS05030
gene id: 1178516:AWR27_RS05030
uniprot id: A0A1P9WTP4
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1178516:AWR27 RS05580
gene id: 1178516:AWR27_RS05580
uniprot id: A0A1P9WU23
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS03585
gene id: 1178516:AWR27_RS03585
uniprot id: A0A1P9WT02
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS06075
gene id: 1178516:AWR27_RS06075
uniprot id: A0A1P9WU55
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1178516:AWR27 RS17805
gene id: 1178516:AWR27_RS17805
uniprot id: A0A1P9X039
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1178516:AWR27 RS01545
gene id: 1178516:AWR27_RS01545
uniprot id: A0A1P9WS02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1178516:AWR27 RS13905
gene id: 1178516:AWR27_RS13905
uniprot id: A0A1P9WY25
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS01150
gene id: 1178516:AWR27_RS01150
uniprot id: A0A1P9WRT0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1178516:AWR27 RS24185
gene id: 1178516:AWR27_RS24185
uniprot id: A0A1P9X399
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1178516:AWR27 RS13835
gene id: 1178516:AWR27_RS13835
uniprot id: A0A1P9WY89
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS03280
gene id: 1178516:AWR27_RS03280
uniprot id: A0A1P9WSV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1178516:AWR27 RS16910
gene id: 1178516:AWR27_RS16910
uniprot id: A0A1P9WZL3
names: Similarity
messages: Belongs to the manganese catalase family.

1178516:AWR27 RS22785
gene id: 1178516:AWR27_RS22785
uniprot id: A0A1P9X2J7
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS08405
gene id: 1178516:AWR27_RS08405
uniprot id: A0A1P9WVA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1178516:AWR27 RS04245
gene id: 1178516:AWR27_RS04245
uniprot id: A0A1P9WT97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1178516:AWR27 RS00165
gene id: 1178516:AWR27_RS00165
uniprot id: A0A1P9WRA9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1178516:AWR27 RS21130
gene id: 1178516:AWR27_RS21130
uniprot id: A0A1P9X4S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1178516:AWR27 RS05020
gene id: 1178516:AWR27_RS05020
uniprot id: A0A1P9X3V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1178516:AWR27 RS19885
gene id: 1178516:AWR27_RS19885
uniprot id: A0A1P9X132
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1178516:AWR27 RS23680
gene id: 1178516:AWR27_RS23680
uniprot id: A0A1P9X2Y4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1178516:AWR27 RS22330
gene id: 1178516:AWR27_RS22330
uniprot id: A0A1P9X296
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1178516:AWR27 RS14730
gene id: 1178516:AWR27_RS14730
uniprot id: A0A1P9WYL1
names: Similarity
messages: Belongs to the peptidase M13 family.

1178516:AWR27 RS04180
gene id: 1178516:AWR27_RS04180
uniprot id: A0A1P9WT91
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1178516:AWR27 RS02730
gene id: 1178516:AWR27_RS02730
uniprot id: A0A1P9WSM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1178516:AWR27 RS22325
gene id: 1178516:AWR27_RS22325
uniprot id: A0A1P9X2B3
names: Subcellular Location Annotation
messages: Cytoplasm

1178516:AWR27 RS21825
gene id: 1178516:AWR27_RS21825
uniprot id: A0A1P9X212
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1178516:AWR27 RS24165
gene id: 1178516:AWR27_RS24165
uniprot id: A0A1P9X376
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1178516:AWR27 RS14885
gene id: 1178516:AWR27_RS14885
uniprot id: A0A1P9WYM9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1178516:AWR27 RS11345
gene id: 1178516:AWR27_RS11345
uniprot id: A0A1P9WWU1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS24530
gene id: 1178516:AWR27_RS24530
uniprot id: A0A1P9X3F3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1178516:AWR27 RS20600
gene id: 1178516:AWR27_RS20600
uniprot id: A0A1P9X1J4
names: Similarity
messages: Belongs to the barstar family.

1178516:AWR27 RS09265
gene id: 1178516:AWR27_RS09265
uniprot id: A0A1P9WVR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1178516:AWR27 RS24685
gene id: 1178516:AWR27_RS24685
uniprot id: A0A1P9X3I0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS20440
gene id: 1178516:AWR27_RS20440
uniprot id: A0A1P9X1E2
names: Similarity
messages: Belongs to the peptidase M16 family.

1178516:AWR27 RS06520
gene id: 1178516:AWR27_RS06520
uniprot id: A0A1P9X427
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS07715
gene id: 1178516:AWR27_RS07715
uniprot id: A0A1P9WV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1178516:AWR27 RS24715
gene id: 1178516:AWR27_RS24715
uniprot id: A0A1P9X3L5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1178516:AWR27 RS02560
gene id: 1178516:AWR27_RS02560
uniprot id: A0A1P9WSG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS04635
gene id: 1178516:AWR27_RS04635
uniprot id: A0A1P9WTK0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1178516:AWR27 RS22315
gene id: 1178516:AWR27_RS22315
uniprot id: A0A1P9X299
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1178516:AWR27 RS23890
gene id: 1178516:AWR27_RS23890
uniprot id: A0A1P9X349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1178516:AWR27 RS23790
gene id: 1178516:AWR27_RS23790
uniprot id: A0A1P9X304
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1178516:AWR27 RS14835
gene id: 1178516:AWR27_RS14835
uniprot id: A0A1P9WYK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1178516:AWR27 RS08720
gene id: 1178516:AWR27_RS08720
uniprot id: A0A1P9WVM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS12440
gene id: 1178516:AWR27_RS12440
uniprot id: A0A1P9WXK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS04515
gene id: 1178516:AWR27_RS04515
uniprot id: A0A1P9WTE9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1178516:AWR27 RS11635
gene id: 1178516:AWR27_RS11635
uniprot id: A0A1P9WX49
names: Similarity
messages: Belongs to the YicC/YloC family.

1178516:AWR27 RS12910
gene id: 1178516:AWR27_RS12910
uniprot id: A0A1P9WXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS17130
gene id: 1178516:AWR27_RS17130
uniprot id: A0A1P9WZR2
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1178516:AWR27 RS05945
gene id: 1178516:AWR27_RS05945
uniprot id: A0A1P9WU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1178516:AWR27 RS15925
gene id: 1178516:AWR27_RS15925
uniprot id: A0A1P9WZ81
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS14515
gene id: 1178516:AWR27_RS14515
uniprot id: A0A1P9WYG7
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1178516:AWR27 RS21560
gene id: 1178516:AWR27_RS21560
uniprot id: A0A1P9X4U1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1178516:AWR27 RS22555
gene id: 1178516:AWR27_RS22555
uniprot id: A0A1P9X2F2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1178516:AWR27 RS05195
gene id: 1178516:AWR27_RS05195
uniprot id: A0A1P9WTR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS10420
gene id: 1178516:AWR27_RS10420
uniprot id: A0A1P9WWC4
names: Similarity
messages: Belongs to the universal stress protein A family.

1178516:AWR27 RS02470
gene id: 1178516:AWR27_RS02470
uniprot id: A0A1P9WSE3
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS10750
gene id: 1178516:AWR27_RS10750
uniprot id: A0A1P9WWJ1
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS18620
gene id: 1178516:AWR27_RS18620
uniprot id: A0A1P9X0G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1178516:AWR27 RS22335
gene id: 1178516:AWR27_RS22335
uniprot id: A0A1P9X2B5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1178516:AWR27 RS19875
gene id: 1178516:AWR27_RS19875
uniprot id: A0A1P9X147
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1178516:AWR27 RS17515
gene id: 1178516:AWR27_RS17515
uniprot id: A0A1P9WZZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1178516:AWR27 RS19980
gene id: 1178516:AWR27_RS19980
uniprot id: A0A1P9X149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1178516:AWR27 RS20875
gene id: 1178516:AWR27_RS20875
uniprot id: A0A1P9X1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1178516:AWR27 RS00380
gene id: 1178516:AWR27_RS00380
uniprot id: A0A1P9WRE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1178516:AWR27 RS11565
gene id: 1178516:AWR27_RS11565
uniprot id: A0A1P9WWX4
names: Similarity
messages: Belongs to the UPF0145 family.

1178516:AWR27 RS24425
gene id: 1178516:AWR27_RS24425
uniprot id: A0A1P9X3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS14305
gene id: 1178516:AWR27_RS14305
uniprot id: A0A1P9WYB0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS16610
gene id: 1178516:AWR27_RS16610
uniprot id: A0A1P9WZL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1178516:AWR27 RS06875
gene id: 1178516:AWR27_RS06875
uniprot id: A0A1P9WUK5
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

1178516:AWR27 RS21005
gene id: 1178516:AWR27_RS21005
uniprot id: A0A1P9X1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1178516:AWR27 RS23490
gene id: 1178516:AWR27_RS23490
uniprot id: A0A1P9X2U9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS01390
gene id: 1178516:AWR27_RS01390
uniprot id: A0A1P9WRZ4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1178516:AWR27 RS00450
gene id: 1178516:AWR27_RS00450
uniprot id: A0A1P9WRG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1178516:AWR27 RS06165
gene id: 1178516:AWR27_RS06165
uniprot id: A0A1P9WU77
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1178516:AWR27 RS19075
gene id: 1178516:AWR27_RS19075
uniprot id: A0A1P9X0Q6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1178516:AWR27 RS20010
gene id: 1178516:AWR27_RS20010
uniprot id: A0A1P9X190
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS16460
gene id: 1178516:AWR27_RS16460
uniprot id: A0A1P9WZF3
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS13745
gene id: 1178516:AWR27_RS13745
uniprot id: A0A1P9WY38
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS20715
gene id: 1178516:AWR27_RS20715
uniprot id: A0A1P9X1H1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1178516:AWR27 RS20690
gene id: 1178516:AWR27_RS20690
uniprot id: A0A1P9X1H7
names: Similarity
messages: Belongs to the TrpF family.

1178516:AWR27 RS07815
gene id: 1178516:AWR27_RS07815
uniprot id: A0A1P9WV05
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1178516:AWR27 RS01460
gene id: 1178516:AWR27_RS01460
uniprot id: A0A1P9WS14
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS00970
gene id: 1178516:AWR27_RS00970
uniprot id: A0A1P9WRP0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1178516:AWR27 RS12515
gene id: 1178516:AWR27_RS12515
uniprot id: A0A1P9WXI4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1178516:AWR27 RS16475
gene id: 1178516:AWR27_RS16475
uniprot id: A0A1P9WZD7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1178516:AWR27 RS10385
gene id: 1178516:AWR27_RS10385
uniprot id: A0A1P9WWH3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS09710
gene id: 1178516:AWR27_RS09710
uniprot id: A0A1P9WW53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1178516:AWR27 RS10455
gene id: 1178516:AWR27_RS10455
uniprot id: A0A1P9WWF7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1178516:AWR27 RS22320
gene id: 1178516:AWR27_RS22320
uniprot id: A0A1P9X2D6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1178516:AWR27 RS07810
gene id: 1178516:AWR27_RS07810
uniprot id: A0A1P9WV08
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1178516:AWR27 RS20570
gene id: 1178516:AWR27_RS20570
uniprot id: A0A1P9X1E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1178516:AWR27 RS16885
gene id: 1178516:AWR27_RS16885
uniprot id: A0A1P9WZM9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS00120
gene id: 1178516:AWR27_RS00120
uniprot id: A0A1P9X3P8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1178516:AWR27 RS18155
gene id: 1178516:AWR27_RS18155
uniprot id: A0A1P9X076
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1178516:AWR27 RS22455
gene id: 1178516:AWR27_RS22455
uniprot id: A0A1P9X2D1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS23335
gene id: 1178516:AWR27_RS23335
uniprot id: A0A1P9X2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1178516:AWR27 RS13300
gene id: 1178516:AWR27_RS13300
uniprot id: A0A1P9WXR0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1178516:AWR27 RS02620
gene id: 1178516:AWR27_RS02620
uniprot id: A0A1P9WSH4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS23835
gene id: 1178516:AWR27_RS23835
uniprot id: A0A1P9X340
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1178516:AWR27 RS14025
gene id: 1178516:AWR27_RS14025
uniprot id: A0A1P9WY78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1178516:AWR27 RS18315
gene id: 1178516:AWR27_RS18315
uniprot id: A0A1P9X0A4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS23025
gene id: 1178516:AWR27_RS23025
uniprot id: A0A1P9X2N7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1178516:AWR27 RS06565
gene id: 1178516:AWR27_RS06565
uniprot id: A0A1P9WUG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS15655
gene id: 1178516:AWR27_RS15655
uniprot id: A0A1P9WZ06
names: Similarity
messages: Belongs to the universal stress protein A family.

1178516:AWR27 RS09700
gene id: 1178516:AWR27_RS09700
uniprot id: A0A1P9WW64
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS20955
gene id: 1178516:AWR27_RS20955
uniprot id: A0A1P9X4T2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS04575
gene id: 1178516:AWR27_RS04575
uniprot id: A0A1P9WTG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS03635
gene id: 1178516:AWR27_RS03635
uniprot id: A0A1P9WT10
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

1178516:AWR27 RS07480
gene id: 1178516:AWR27_RS07480
uniprot id: A0A1P9WUV8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1178516:AWR27 RS20330
gene id: 1178516:AWR27_RS20330
uniprot id: A0A1P9X1A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1178516:AWR27 RS17770
gene id: 1178516:AWR27_RS17770
uniprot id: A0A1P9X013
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS21550
gene id: 1178516:AWR27_RS21550
uniprot id: A0A1P9X1Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1178516:AWR27 RS07405
gene id: 1178516:AWR27_RS07405
uniprot id: A0A1P9WUU5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS00650
gene id: 1178516:AWR27_RS00650
uniprot id: A0A1P9WRI2
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS00730
gene id: 1178516:AWR27_RS00730
uniprot id: A0A1P9WRL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1178516:AWR27 RS13620
gene id: 1178516:AWR27_RS13620
uniprot id: A0A1P9WXZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS03835
gene id: 1178516:AWR27_RS03835
uniprot id: A0A1P9WT35
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1178516:AWR27 RS03355
gene id: 1178516:AWR27_RS03355
uniprot id: A0A1P9WSS8
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19000
gene id: 1178516:AWR27_RS19000
uniprot id: A0A1P9X0R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1178516:AWR27 RS02215
gene id: 1178516:AWR27_RS02215
uniprot id: A0A1P9WS95
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS15030
gene id: 1178516:AWR27_RS15030
uniprot id: A0A1P9WYN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS16250
gene id: 1178516:AWR27_RS16250
uniprot id: A0A1P9WZA4
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS01025
gene id: 1178516:AWR27_RS01025
uniprot id: A0A1P9WRS1
names: Similarity
messages: Belongs to the peptidase S41A family.

1178516:AWR27 RS25195
gene id: 1178516:AWR27_RS25195
uniprot id: A0A1P9X3Z8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1178516:AWR27 RS20505
gene id: 1178516:AWR27_RS20505
uniprot id: A0A1P9X1D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1178516:AWR27 RS24755
gene id: 1178516:AWR27_RS24755
uniprot id: A0A1P9X3I8
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS17700
gene id: 1178516:AWR27_RS17700
uniprot id: A0A1P9X052
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1178516:AWR27 RS00740
gene id: 1178516:AWR27_RS00740
uniprot id: A0A1P9WRL6
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1178516:AWR27 RS20915
gene id: 1178516:AWR27_RS20915
uniprot id: A0A1P9X1L6
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1178516:AWR27 RS13845
gene id: 1178516:AWR27_RS13845
uniprot id: A0A1P9WY49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS11465
gene id: 1178516:AWR27_RS11465
uniprot id: A0A1P9WWW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1178516:AWR27 RS01105
gene id: 1178516:AWR27_RS01105
uniprot id: A0A1P9WRS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1178516:AWR27 RS24135
gene id: 1178516:AWR27_RS24135
uniprot id: A0A1P9X362
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1178516:AWR27 RS00820
gene id: 1178516:AWR27_RS00820
uniprot id: A0A1P9WRM2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1178516:AWR27 RS23710
gene id: 1178516:AWR27_RS23710
uniprot id: A0A1P9X2Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1178516:AWR27 RS06695
gene id: 1178516:AWR27_RS06695
uniprot id: A0A1P9WUH8
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS22305
gene id: 1178516:AWR27_RS22305
uniprot id: A0A1P9X2D9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1178516:AWR27 RS05125
gene id: 1178516:AWR27_RS05125
uniprot id: A0A1P9X3Y6
names: Similarity
messages: Belongs to the peptidase S9C family.

1178516:AWR27 RS09735
gene id: 1178516:AWR27_RS09735
uniprot id: A0A1P9WW08
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS06990
gene id: 1178516:AWR27_RS06990
uniprot id: A0A1P9WUR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1178516:AWR27 RS00055
gene id: 1178516:AWR27_RS00055
uniprot id: A0A1P9WR84
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1178516:AWR27 RS02720
gene id: 1178516:AWR27_RS02720
uniprot id: A0A1P9WSJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

1178516:AWR27 RS02810
gene id: 1178516:AWR27_RS02810
uniprot id: A0A1P9WSJ1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1178516:AWR27 RS15795
gene id: 1178516:AWR27_RS15795
uniprot id: A0A1P9WZ18
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS12305
gene id: 1178516:AWR27_RS12305
uniprot id: A0A1P9WX99
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1178516:AWR27 RS12980
gene id: 1178516:AWR27_RS12980
uniprot id: A0A1P9WXP8
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS17410
gene id: 1178516:AWR27_RS17410
uniprot id: A0A1P9WZY8
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

1178516:AWR27 RS18730
gene id: 1178516:AWR27_RS18730
uniprot id: A0A1P9X0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1178516:AWR27 RS00720
gene id: 1178516:AWR27_RS00720
uniprot id: A0A1P9WRK4
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1178516:AWR27 RS03115
gene id: 1178516:AWR27_RS03115
uniprot id: A0A1P9WSQ6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1178516:AWR27 RS11945
gene id: 1178516:AWR27_RS11945
uniprot id: A0A1P9WX82
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS14800
gene id: 1178516:AWR27_RS14800
uniprot id: A0A1P9WYJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1178516:AWR27 RS14280
gene id: 1178516:AWR27_RS14280
uniprot id: A0A1P9WYA5
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

1178516:AWR27 RS11735
gene id: 1178516:AWR27_RS11735
uniprot id: A0A1P9WX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1178516:AWR27 RS23405
gene id: 1178516:AWR27_RS23405
uniprot id: A0A1P9X4Y3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1178516:AWR27 RS18000
gene id: 1178516:AWR27_RS18000
uniprot id: A0A1P9X059
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS16275
gene id: 1178516:AWR27_RS16275
uniprot id: A0A1P9WZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1178516:AWR27 RS10415
gene id: 1178516:AWR27_RS10415
uniprot id: A0A1P9WWD5
names: Similarity
messages: Belongs to the universal stress protein A family.

1178516:AWR27 RS24485
gene id: 1178516:AWR27_RS24485
uniprot id: A0A1P9X3D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1178516:AWR27 RS23840
gene id: 1178516:AWR27_RS23840
uniprot id: A0A1P9X317
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1178516:AWR27 RS03315
gene id: 1178516:AWR27_RS03315
uniprot id: A0A1P9WSV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1178516:AWR27 RS03030
gene id: 1178516:AWR27_RS03030
uniprot id: A0A1P9WSP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1178516:AWR27 RS01875
gene id: 1178516:AWR27_RS01875
uniprot id: A0A1P9WS79
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS02270
gene id: 1178516:AWR27_RS02270
uniprot id: A0A1P9WS99
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1178516:AWR27 RS05290
gene id: 1178516:AWR27_RS05290
uniprot id: A0A1P9WTS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS22980
gene id: 1178516:AWR27_RS22980
uniprot id: A0A1P9X2P4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1178516:AWR27 RS08000
gene id: 1178516:AWR27_RS08000
uniprot id: A0A1P9WVA5
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS20130
gene id: 1178516:AWR27_RS20130
uniprot id: A0A1P9X184
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1178516:AWR27 RS07490
gene id: 1178516:AWR27_RS07490
uniprot id: A0A1P9WUY5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1178516:AWR27 RS18305
gene id: 1178516:AWR27_RS18305
uniprot id: A0A1P9X0F3
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19540
gene id: 1178516:AWR27_RS19540
uniprot id: A0A1P9X0Y2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS08715
gene id: 1178516:AWR27_RS08715
uniprot id: A0A1P9WVG1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1178516:AWR27 RS23785
gene id: 1178516:AWR27_RS23785
uniprot id: A0A1P9X330
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1178516:AWR27 RS14955
gene id: 1178516:AWR27_RS14955
uniprot id: A0A1P9WYM8
names: Similarity
messages: Belongs to the peptidase C10 family.

1178516:AWR27 RS04475
gene id: 1178516:AWR27_RS04475
uniprot id: A0A1P9WTE2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1178516:AWR27 RS04535
gene id: 1178516:AWR27_RS04535
uniprot id: A0A1P9WTI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1178516:AWR27 RS08635
gene id: 1178516:AWR27_RS08635
uniprot id: A0A1P9WVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS12095
gene id: 1178516:AWR27_RS12095
uniprot id: A0A1P9WXA4
names: Similarity
messages: Belongs to the YoeB family.

1178516:AWR27 RS14225
gene id: 1178516:AWR27_RS14225
uniprot id: A0A1P9WYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1178516:AWR27 RS20710
gene id: 1178516:AWR27_RS20710
uniprot id: A0A1P9X1L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1178516:AWR27 RS10240
gene id: 1178516:AWR27_RS10240
uniprot id: A0A1P9WW86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS00495
gene id: 1178516:AWR27_RS00495
uniprot id: A0A1P9WRG9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1178516:AWR27 RS03605
gene id: 1178516:AWR27_RS03605
uniprot id: A0A1P9WT45
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1178516:AWR27 RS05380
gene id: 1178516:AWR27_RS05380
uniprot id: A0A1P9WTY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1178516:AWR27 RS03620
gene id: 1178516:AWR27_RS03620
uniprot id: A0A1P9WSX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS18750
gene id: 1178516:AWR27_RS18750
uniprot id: A0A1P9X0N5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1178516:AWR27 RS22820
gene id: 1178516:AWR27_RS22820
uniprot id: A0A1P9X2M0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1178516:AWR27 RS24725
gene id: 1178516:AWR27_RS24725
uniprot id: A0A1P9X3G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1178516:AWR27 RS03965
gene id: 1178516:AWR27_RS03965
uniprot id: A0A1P9WT77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1178516:AWR27 RS05005
gene id: 1178516:AWR27_RS05005
uniprot id: A0A1P9WTR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS01205
gene id: 1178516:AWR27_RS01205
uniprot id: A0A1P9WRT8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1178516:AWR27 RS01330
gene id: 1178516:AWR27_RS01330
uniprot id: A0A1P9WRY0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS22840
gene id: 1178516:AWR27_RS22840
uniprot id: A0A1P9X2J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1178516:AWR27 RS22030
gene id: 1178516:AWR27_RS22030
uniprot id: A0A1P9X245
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1178516:AWR27 RS07375
gene id: 1178516:AWR27_RS07375
uniprot id: A0A1P9WUS9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS01980
gene id: 1178516:AWR27_RS01980
uniprot id: A0A1P9WS96
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1178516:AWR27 RS06105
gene id: 1178516:AWR27_RS06105
uniprot id: A0A1P9WUB3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1178516:AWR27 RS05665
gene id: 1178516:AWR27_RS05665
uniprot id: A0A1P9WU28
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1178516:AWR27 RS23250
gene id: 1178516:AWR27_RS23250
uniprot id: A0A1P9X2U0
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS08115
gene id: 1178516:AWR27_RS08115
uniprot id: A0A1P9WV86
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS23810
gene id: 1178516:AWR27_RS23810
uniprot id: A0A1P9X313
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1178516:AWR27 RS02980
gene id: 1178516:AWR27_RS02980
uniprot id: A0A1P9WSL9
names: Similarity
messages: Belongs to the peptidase C40 family.

1178516:AWR27 RS22700
gene id: 1178516:AWR27_RS22700
uniprot id: A0A1P9X2G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1178516:AWR27 RS20265
gene id: 1178516:AWR27_RS20265
uniprot id: A0A1P9X1A9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS13190
gene id: 1178516:AWR27_RS13190
uniprot id: A0A1P9WXT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1178516:AWR27 RS11430
gene id: 1178516:AWR27_RS11430
uniprot id: A0A1P9WWZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS13240
gene id: 1178516:AWR27_RS13240
uniprot id: A0A1P9WXS3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS09425
gene id: 1178516:AWR27_RS09425
uniprot id: A0A1P9WVT9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1178516:AWR27 RS14125
gene id: 1178516:AWR27_RS14125
uniprot id: A0A1P9WY79
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1178516:AWR27 RS17205
gene id: 1178516:AWR27_RS17205
uniprot id: A0A1P9WZT6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1178516:AWR27 RS07220
gene id: 1178516:AWR27_RS07220
uniprot id: A0A1P9WUW3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS12070
gene id: 1178516:AWR27_RS12070
uniprot id: A0A1P9WX64
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1178516:AWR27 RS07140
gene id: 1178516:AWR27_RS07140
uniprot id: A0A1P9WUN6
names: Similarity
messages: Belongs to the IlvD/Edd family.

1178516:AWR27 RS13430
gene id: 1178516:AWR27_RS13430
uniprot id: A0A1P9WY07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS08100
gene id: 1178516:AWR27_RS08100
uniprot id: A0A1P9WVC0
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS06925
gene id: 1178516:AWR27_RS06925
uniprot id: A0A1P9WUL8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1178516:AWR27 RS02120
gene id: 1178516:AWR27_RS02120
uniprot id: A0A1P9WSB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS25695
gene id: 1178516:AWR27_RS25695
uniprot id: A0A1P9WTV2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS22775
gene id: 1178516:AWR27_RS22775
uniprot id: A0A1P9X2J6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1178516:AWR27 RS13150
gene id: 1178516:AWR27_RS13150
uniprot id: A0A1P9WXS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS00280
gene id: 1178516:AWR27_RS00280
uniprot id: A0A1P9WRD0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS00690
gene id: 1178516:AWR27_RS00690
uniprot id: A0A1P9WRK2
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS03045
gene id: 1178516:AWR27_RS03045
uniprot id: A0A1P9WSQ4
names: Similarity
messages: Belongs to the aldose epimerase family.

1178516:AWR27 RS23445
gene id: 1178516:AWR27_RS23445
uniprot id: A0A1P9X2W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS10615
gene id: 1178516:AWR27_RS10615
uniprot id: A0A1P9WWF0
names: Similarity
messages: Belongs to the EPSP synthase family.

1178516:AWR27 RS03035
gene id: 1178516:AWR27_RS03035
uniprot id: A0A1P9WSN4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS12110
gene id: 1178516:AWR27_RS12110
uniprot id: A0A1P9WXA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1178516:AWR27 RS14790
gene id: 1178516:AWR27_RS14790
uniprot id: A0A1P9WYM3
names: Similarity
messages: Belongs to the GroES chaperonin family.

1178516:AWR27 RS10150
gene id: 1178516:AWR27_RS10150
uniprot id: A0A1P9WW81
names: Similarity
messages: Belongs to the DprA/Smf family.

1178516:AWR27 RS22620
gene id: 1178516:AWR27_RS22620
uniprot id: A0A1P9X2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1178516:AWR27 RS18960
gene id: 1178516:AWR27_RS18960
uniprot id: A0A1P9X0L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1178516:AWR27 RS16380
gene id: 1178516:AWR27_RS16380
uniprot id: A0A1P9WZC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1178516:AWR27 RS22300
gene id: 1178516:AWR27_RS22300
uniprot id: A0A1P9X298
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1178516:AWR27 RS21000
gene id: 1178516:AWR27_RS21000
uniprot id: A0A1P9X1P3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1178516:AWR27 RS15685
gene id: 1178516:AWR27_RS15685
uniprot id: A0A1P9WYZ9
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS05335
gene id: 1178516:AWR27_RS05335
uniprot id: A0A1P9WTT7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1178516:AWR27 RS15465
gene id: 1178516:AWR27_RS15465
uniprot id: A0A1P9WYX1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1178516:AWR27 RS12965
gene id: 1178516:AWR27_RS12965
uniprot id: A0A1P9X4A3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS02310
gene id: 1178516:AWR27_RS02310
uniprot id: A0A1P9WSD6
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS17695
gene id: 1178516:AWR27_RS17695
uniprot id: A0A1P9X4J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS01695
gene id: 1178516:AWR27_RS01695
uniprot id: A0A1P9WS24
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS11520
gene id: 1178516:AWR27_RS11520
uniprot id: A0A1P9WWV8
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1178516:AWR27 RS11625
gene id: 1178516:AWR27_RS11625
uniprot id: A0A1P9WWY2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1178516:AWR27 RS09535
gene id: 1178516:AWR27_RS09535
uniprot id: A0A1P9WVW0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1178516:AWR27 RS04715
gene id: 1178516:AWR27_RS04715
uniprot id: A0A1P9WTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS01160
gene id: 1178516:AWR27_RS01160
uniprot id: A0A1P9WRV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1178516:AWR27 RS24050
gene id: 1178516:AWR27_RS24050
uniprot id: A0A1P9X356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1178516:AWR27 RS23985
gene id: 1178516:AWR27_RS23985
uniprot id: A0A1P9X379
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS08080
gene id: 1178516:AWR27_RS08080
uniprot id: A0A1P9WV66
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1178516:AWR27 RS10510
gene id: 1178516:AWR27_RS10510
uniprot id: A0A1P9WWC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1178516:AWR27 RS23755
gene id: 1178516:AWR27_RS23755
uniprot id: A0A1P9X302
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1178516:AWR27 RS20405
gene id: 1178516:AWR27_RS20405
uniprot id: A0A1P9X1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1178516:AWR27 RS14270
gene id: 1178516:AWR27_RS14270
uniprot id: A0A1P9WYA9
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS14235
gene id: 1178516:AWR27_RS14235
uniprot id: A0A1P9WY91
names: Similarity
messages: Belongs to the peptidase M1 family.

1178516:AWR27 RS20765
gene id: 1178516:AWR27_RS20765
uniprot id: A0A1P9X1M1
names: Similarity
messages: Belongs to the serpin family.

1178516:AWR27 RS21405
gene id: 1178516:AWR27_RS21405
uniprot id: A0A1P9X1Y2
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1178516:AWR27 RS13710
gene id: 1178516:AWR27_RS13710
uniprot id: A0A1P9WXZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1178516:AWR27 RS24220
gene id: 1178516:AWR27_RS24220
uniprot id: A0A1P9X3A7
names: Similarity
messages: Belongs to the SCO1/2 family.

1178516:AWR27 RS01360
gene id: 1178516:AWR27_RS01360
uniprot id: A0A1P9X3S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS08875
gene id: 1178516:AWR27_RS08875
uniprot id: A0A1P9WVJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1178516:AWR27 RS01550
gene id: 1178516:AWR27_RS01550
uniprot id: A0A1P9X3U3
names: Similarity
messages: Belongs to the SUI1 family.

1178516:AWR27 RS02935
gene id: 1178516:AWR27_RS02935
uniprot id: A0A1P9WSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1178516:AWR27 RS12135
gene id: 1178516:AWR27_RS12135
uniprot id: A0A1P9WXE6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS00025
gene id: 1178516:AWR27_RS00025
uniprot id: A0A1P9WR88
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1178516:AWR27 RS24105
gene id: 1178516:AWR27_RS24105
uniprot id: A0A1P9X355
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS24195
gene id: 1178516:AWR27_RS24195
uniprot id: A0A1P9X396
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS10835
gene id: 1178516:AWR27_RS10835
uniprot id: A0A1P9WWJ3
names: Similarity
messages: Belongs to the glutamine synthetase family.

1178516:AWR27 RS12660
gene id: 1178516:AWR27_RS12660
uniprot id: A0A1P9WXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1178516:AWR27 RS11215
gene id: 1178516:AWR27_RS11215
uniprot id: A0A1P9WWR8
names: Similarity
messages: Belongs to the oxoprolinase family.

1178516:AWR27 RS12020
gene id: 1178516:AWR27_RS12020
uniprot id: A0A1P9WX57
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS05015
gene id: 1178516:AWR27_RS05015
uniprot id: A0A1P9WTS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1178516:AWR27 RS25615
gene id: 1178516:AWR27_RS25615
uniprot id: A0A1P9X2I0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1178516:AWR27 RS23825
gene id: 1178516:AWR27_RS23825
uniprot id: A0A1P9X322
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1178516:AWR27 RS05570
gene id: 1178516:AWR27_RS05570
uniprot id: A0A1P9WTX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1178516:AWR27 RS23140
gene id: 1178516:AWR27_RS23140
uniprot id: A0A1P9X2P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1178516:AWR27 RS19305
gene id: 1178516:AWR27_RS19305
uniprot id: A0A1P9X0X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1178516:AWR27 RS14020
gene id: 1178516:AWR27_RS14020
uniprot id: A0A1P9WY86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1178516:AWR27 RS18505
gene id: 1178516:AWR27_RS18505
uniprot id: A0A1P9X0J0
names: Similarity
messages: Belongs to the thioredoxin family.

1178516:AWR27 RS22070
gene id: 1178516:AWR27_RS22070
uniprot id: A0A1P9X271
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1178516:AWR27 RS09995
gene id: 1178516:AWR27_RS09995
uniprot id: A0A1P9WW51
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1178516:AWR27 RS19270
gene id: 1178516:AWR27_RS19270
uniprot id: A0A1P9X0W2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1178516:AWR27 RS17415
gene id: 1178516:AWR27_RS17415
uniprot id: A0A1P9WZV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1178516:AWR27 RS14495
gene id: 1178516:AWR27_RS14495
uniprot id: A0A1P9WYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1178516:AWR27 RS18060
gene id: 1178516:AWR27_RS18060
uniprot id: A0A1P9X0A9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1178516:AWR27 RS06985
gene id: 1178516:AWR27_RS06985
uniprot id: A0A1P9WUP9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS08545
gene id: 1178516:AWR27_RS08545
uniprot id: A0A1P9WVF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1178516:AWR27 RS17795
gene id: 1178516:AWR27_RS17795
uniprot id: A0A1P9X021
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS24310
gene id: 1178516:AWR27_RS24310
uniprot id: A0A1P9X3A2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1178516:AWR27 RS01370
gene id: 1178516:AWR27_RS01370
uniprot id: A0A1P9WRW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS12645
gene id: 1178516:AWR27_RS12645
uniprot id: A0A1P9WXG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1178516:AWR27 RS21110
gene id: 1178516:AWR27_RS21110
uniprot id: A0A1P9X1T5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1178516:AWR27 RS09610
gene id: 1178516:AWR27_RS09610
uniprot id: A0A1P9WW29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1178516:AWR27 RS24300
gene id: 1178516:AWR27_RS24300
uniprot id: A0A1P9X395
names: Similarity
messages: Belongs to the DEAD box helicase family.

1178516:AWR27 RS21585
gene id: 1178516:AWR27_RS21585
uniprot id: A0A1P9X1X7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1178516:AWR27 RS24305
gene id: 1178516:AWR27_RS24305
uniprot id: A0A1P9X3B6
names: Similarity
messages: Belongs to the fructosamine kinase family.

1178516:AWR27 RS18345
gene id: 1178516:AWR27_RS18345
uniprot id: A0A1P9X0C8
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19245
gene id: 1178516:AWR27_RS19245
uniprot id: A0A1P9X0W7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1178516:AWR27 RS23145
gene id: 1178516:AWR27_RS23145
uniprot id: A0A1P9X2S0
names: Similarity
messages: Belongs to the RutC family.

1178516:AWR27 RS01210
gene id: 1178516:AWR27_RS01210
uniprot id: A0A1P9WRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1178516:AWR27 RS23820
gene id: 1178516:AWR27_RS23820
uniprot id: A0A1P9X343
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1178516:AWR27 RS15060
gene id: 1178516:AWR27_RS15060
uniprot id: A0A1P9WYP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1178516:AWR27 RS01240
gene id: 1178516:AWR27_RS01240
uniprot id: A0A1P9WRU0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1178516:AWR27 RS12755
gene id: 1178516:AWR27_RS12755
uniprot id: A0A1P9WXQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1178516:AWR27 RS20260
gene id: 1178516:AWR27_RS20260
uniprot id: A0A1P9X1B0
names: Cofactor
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1178516:AWR27 RS00920
gene id: 1178516:AWR27_RS00920
uniprot id: A0A1P9WRP3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1178516:AWR27 RS18830
gene id: 1178516:AWR27_RS18830
uniprot id: A0A1P9X0N3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1178516:AWR27 RS18685
gene id: 1178516:AWR27_RS18685
uniprot id: A0A1P9X0M4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS08960
gene id: 1178516:AWR27_RS08960
uniprot id: A0A1P9WVL3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS06470
gene id: 1178516:AWR27_RS06470
uniprot id: A0A1P9WUD4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS14645
gene id: 1178516:AWR27_RS14645
uniprot id: A0A1P9WYN2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1178516:AWR27 RS04685
gene id: 1178516:AWR27_RS04685
uniprot id: A0A1P9WTI4
names: Similarity
messages: Belongs to the isochorismate synthase family.

1178516:AWR27 RS21605
gene id: 1178516:AWR27_RS21605
uniprot id: A0A1P9X214
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1178516:AWR27 RS19545
gene id: 1178516:AWR27_RS19545
uniprot id: A0A1P9X121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS19870
gene id: 1178516:AWR27_RS19870
uniprot id: A0A1P9X173
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1178516:AWR27 RS24205
gene id: 1178516:AWR27_RS24205
uniprot id: A0A1P9X3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS06840
gene id: 1178516:AWR27_RS06840
uniprot id: A0A1P9WUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS21265
gene id: 1178516:AWR27_RS21265
uniprot id: A0A1P9X1V3
names: Similarity
messages: Belongs to the FMO family.

1178516:AWR27 RS10695
gene id: 1178516:AWR27_RS10695
uniprot id: A0A1P9WWJ6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS20465
gene id: 1178516:AWR27_RS20465
uniprot id: A0A1P9X1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS05780
gene id: 1178516:AWR27_RS05780
uniprot id: A0A1P9WU04
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1178516:AWR27 RS21415
gene id: 1178516:AWR27_RS21415
uniprot id: A0A1P9X1Y3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1178516:AWR27 RS15165
gene id: 1178516:AWR27_RS15165
uniprot id: A0A1P9WYS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS16385
gene id: 1178516:AWR27_RS16385
uniprot id: A0A1P9WZC9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1178516:AWR27 RS12130
gene id: 1178516:AWR27_RS12130
uniprot id: A0A1P9WX75
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1178516:AWR27 RS07595
gene id: 1178516:AWR27_RS07595
uniprot id: A0A1P9WUW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1178516:AWR27 RS04080
gene id: 1178516:AWR27_RS04080
uniprot id: A0A1P9WTA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1178516:AWR27 RS24855
gene id: 1178516:AWR27_RS24855
uniprot id: A0A1P9X3K8
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS17070
gene id: 1178516:AWR27_RS17070
uniprot id: A0A1P9WZS8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS15640
gene id: 1178516:AWR27_RS15640
uniprot id: A0A1P9WYZ8
names: Similarity
messages: Belongs to the universal stress protein A family.

1178516:AWR27 RS23815
gene id: 1178516:AWR27_RS23815
uniprot id: A0A1P9X314
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1178516:AWR27 RS05065
gene id: 1178516:AWR27_RS05065
uniprot id: A0A1P9WTP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1178516:AWR27 RS02770
gene id: 1178516:AWR27_RS02770
uniprot id: A0A1P9WSM1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1178516:AWR27 RS18875
gene id: 1178516:AWR27_RS18875
uniprot id: A0A1P9X0J7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1178516:AWR27 RS11485
gene id: 1178516:AWR27_RS11485
uniprot id: A0A1P9WX06
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1178516:AWR27 RS04435
gene id: 1178516:AWR27_RS04435
uniprot id: A0A1P9WTD4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS02245
gene id: 1178516:AWR27_RS02245
uniprot id: A0A1P9WSC8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1178516:AWR27 RS12750
gene id: 1178516:AWR27_RS12750
uniprot id: A0A1P9WXJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1178516:AWR27 RS02960
gene id: 1178516:AWR27_RS02960
uniprot id: A0A1P9WSN7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS19195
gene id: 1178516:AWR27_RS19195
uniprot id: A0A1P9X0V4
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1178516:AWR27 RS05310
gene id: 1178516:AWR27_RS05310
uniprot id: A0A1P9WTW3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS08075
gene id: 1178516:AWR27_RS08075
uniprot id: A0A1P9WV73
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1178516:AWR27 RS21730
gene id: 1178516:AWR27_RS21730
uniprot id: A0A1P9X237
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1178516:AWR27 RS03600
gene id: 1178516:AWR27_RS03600
uniprot id: A0A1P9WT14
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS19920
gene id: 1178516:AWR27_RS19920
uniprot id: A0A1P9X140
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1178516:AWR27 RS04670
gene id: 1178516:AWR27_RS04670
uniprot id: A0A1P9WTG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1178516:AWR27 RS22930
gene id: 1178516:AWR27_RS22930
uniprot id: A0A1P9X2K0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1178516:AWR27 RS07510
gene id: 1178516:AWR27_RS07510
uniprot id: A0A1P9WUZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS21655
gene id: 1178516:AWR27_RS21655
uniprot id: A0A1P9X223
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1178516:AWR27 RS18725
gene id: 1178516:AWR27_RS18725
uniprot id: A0A1P9X0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1178516:AWR27 RS13445
gene id: 1178516:AWR27_RS13445
uniprot id: A0A1P9WXV9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1178516:AWR27 RS06765
gene id: 1178516:AWR27_RS06765
uniprot id: A0A1P9WUM3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1178516:AWR27 RS09500
gene id: 1178516:AWR27_RS09500
uniprot id: A0A1P9WVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS24735
gene id: 1178516:AWR27_RS24735
uniprot id: A0A1P9X3G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1178516:AWR27 RS17230
gene id: 1178516:AWR27_RS17230
uniprot id: A0A1P9WZQ8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1178516:AWR27 RS05470
gene id: 1178516:AWR27_RS05470
uniprot id: A0A1P9WU06
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1178516:AWR27 RS22575
gene id: 1178516:AWR27_RS22575
uniprot id: A0A1P9X2E8
names: Similarity
messages: Belongs to the UPF0162 family.

1178516:AWR27 RS04460
gene id: 1178516:AWR27_RS04460
uniprot id: A0A1P9WTG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1178516:AWR27 RS17725
gene id: 1178516:AWR27_RS17725
uniprot id: A0A1P9X008
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1178516:AWR27 RS07620
gene id: 1178516:AWR27_RS07620
uniprot id: A0A1P9WUY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS17710
gene id: 1178516:AWR27_RS17710
uniprot id: A0A1P9X024
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1178516:AWR27 RS12950
gene id: 1178516:AWR27_RS12950
uniprot id: A0A1P9WXN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1178516:AWR27 RS05050
gene id: 1178516:AWR27_RS05050
uniprot id: A0A1P9WTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS22210
gene id: 1178516:AWR27_RS22210
uniprot id: A0A1P9X2B6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS03285
gene id: 1178516:AWR27_RS03285
uniprot id: A0A1P9WSY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1178516:AWR27 RS19645
gene id: 1178516:AWR27_RS19645
uniprot id: A0A1P9X135
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS11860
gene id: 1178516:AWR27_RS11860
uniprot id: A0A1P9WX15
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1178516:AWR27 RS04385
gene id: 1178516:AWR27_RS04385
uniprot id: A0A1P9WTC6
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS22235
gene id: 1178516:AWR27_RS22235
uniprot id: A0A1P9X2B8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS08460
gene id: 1178516:AWR27_RS08460
uniprot id: A0A1P9WVC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS23795
gene id: 1178516:AWR27_RS23795
uniprot id: A0A1P9X327
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1178516:AWR27 RS04110
gene id: 1178516:AWR27_RS04110
uniprot id: A0A1P9WTD0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1178516:AWR27 RS05400
gene id: 1178516:AWR27_RS05400
uniprot id: A0A1P9WTV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1178516:AWR27 RS13880
gene id: 1178516:AWR27_RS13880
uniprot id: A0A1P9WY26
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS00670
gene id: 1178516:AWR27_RS00670
uniprot id: A0A1P9WRJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS21155
gene id: 1178516:AWR27_RS21155
uniprot id: A0A1P9X1Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1178516:AWR27 RS06065
gene id: 1178516:AWR27_RS06065
uniprot id: A0A1P9WUA5
names: Similarity
messages: Belongs to the HypD family.

1178516:AWR27 RS08915
gene id: 1178516:AWR27_RS08915
uniprot id: A0A1P9WVK4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS11065
gene id: 1178516:AWR27_RS11065
uniprot id: A0A1P9WWV6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1178516:AWR27 RS21190
gene id: 1178516:AWR27_RS21190
uniprot id: A0A1P9X1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1178516:AWR27 RS22090
gene id: 1178516:AWR27_RS22090
uniprot id: A0A1P9X2A0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1178516:AWR27 RS08810
gene id: 1178516:AWR27_RS08810
uniprot id: A0A1P9WVI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1178516:AWR27 RS22590
gene id: 1178516:AWR27_RS22590
uniprot id: A0A1P9X2E7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1178516:AWR27 RS02865
gene id: 1178516:AWR27_RS02865
uniprot id: A0A1P9WSK2
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS22640
gene id: 1178516:AWR27_RS22640
uniprot id: A0A1P9X2F4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1178516:AWR27 RS07500
gene id: 1178516:AWR27_RS07500
uniprot id: A0A1P9WUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1178516:AWR27 RS20680
gene id: 1178516:AWR27_RS20680
uniprot id: A0A1P9X1G5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS23930
gene id: 1178516:AWR27_RS23930
uniprot id: A0A1P9X361
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1178516:AWR27 RS21960
gene id: 1178516:AWR27_RS21960
uniprot id: A0A1P9X4Q8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1178516:AWR27 RS02015
gene id: 1178516:AWR27_RS02015
uniprot id: A0A1P9X3P9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS04090
gene id: 1178516:AWR27_RS04090
uniprot id: A0A1P9WTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1178516:AWR27 RS22925
gene id: 1178516:AWR27_RS22925
uniprot id: A0A1P9X2N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1178516:AWR27 RS06465
gene id: 1178516:AWR27_RS06465
uniprot id: A0A1P9WUH7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1178516:AWR27 RS17620
gene id: 1178516:AWR27_RS17620
uniprot id: A0A1P9X015
names: Similarity
messages: Belongs to the BshC family.

1178516:AWR27 RS19955
gene id: 1178516:AWR27_RS19955
uniprot id: A0A1P9X155
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS05300
gene id: 1178516:AWR27_RS05300
uniprot id: A0A1P9WTT2
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS07275
gene id: 1178516:AWR27_RS07275
uniprot id: A0A1P9WUU2
names: Similarity
messages: Belongs to the peptidase S49 family.

1178516:AWR27 RS11605
gene id: 1178516:AWR27_RS11605
uniprot id: A0A1P9WWX3
names: Similarity
messages: Belongs to the UxaA family.

1178516:AWR27 RS12040
gene id: 1178516:AWR27_RS12040
uniprot id: A0A1P9WX77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS04400
gene id: 1178516:AWR27_RS04400
uniprot id: A0A1P9WTD7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS03945
gene id: 1178516:AWR27_RS03945
uniprot id: A0A1P9WT56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1178516:AWR27 RS02925
gene id: 1178516:AWR27_RS02925
uniprot id: A0A1P9WSL1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS18825
gene id: 1178516:AWR27_RS18825
uniprot id: A0A1P9X0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1178516:AWR27 RS11785
gene id: 1178516:AWR27_RS11785
uniprot id: A0A1P9WX51
names: Similarity
messages: Belongs to the aldose epimerase family.

1178516:AWR27 RS19230
gene id: 1178516:AWR27_RS19230
uniprot id: A0A1P9X0S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1178516:AWR27 RS02680
gene id: 1178516:AWR27_RS02680
uniprot id: A0A1P9WSH0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS01030
gene id: 1178516:AWR27_RS01030
uniprot id: A0A1P9WRR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1178516:AWR27 RS18515
gene id: 1178516:AWR27_RS18515
uniprot id: A0A1P9X0J5
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS15705
gene id: 1178516:AWR27_RS15705
uniprot id: A0A1P9WZ14
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1178516:AWR27 RS18975
gene id: 1178516:AWR27_RS18975
uniprot id: A0A1P9X0R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1178516:AWR27 RS10360
gene id: 1178516:AWR27_RS10360
uniprot id: A0A1P9WWB4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS13840
gene id: 1178516:AWR27_RS13840
uniprot id: A0A1P9WY32
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS13680
gene id: 1178516:AWR27_RS13680
uniprot id: A0A1P9WXX7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1178516:AWR27 RS20070
gene id: 1178516:AWR27_RS20070
uniprot id: A0A1P9X172
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1178516:AWR27 RS20285
gene id: 1178516:AWR27_RS20285
uniprot id: A0A1P9X1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1178516:AWR27 RS12620
gene id: 1178516:AWR27_RS12620
uniprot id: A0A1P9WXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1178516:AWR27 RS05080
gene id: 1178516:AWR27_RS05080
uniprot id: A0A1P9WTT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS17460
gene id: 1178516:AWR27_RS17460
uniprot id: A0A1P9WZV0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1178516:AWR27 RS00005
gene id: 1178516:AWR27_RS00005
uniprot id: A0A1P9WR79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1178516:AWR27 RS23880
gene id: 1178516:AWR27_RS23880
uniprot id: A0A1P9X318
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1178516:AWR27 RS08205
gene id: 1178516:AWR27_RS08205
uniprot id: A0A1P9X410
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS18320
gene id: 1178516:AWR27_RS18320
uniprot id: A0A1P9X0D9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS24825
gene id: 1178516:AWR27_RS24825
uniprot id: A0A1P9X3N5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1178516:AWR27 RS18130
gene id: 1178516:AWR27_RS18130
uniprot id: A0A1P9X0C7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS15520
gene id: 1178516:AWR27_RS15520
uniprot id: A0A1P9WYX9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1178516:AWR27 RS02035
gene id: 1178516:AWR27_RS02035
uniprot id: A0A1P9WS88
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1178516:AWR27 RS15380
gene id: 1178516:AWR27_RS15380
uniprot id: A0A1P9WZ11
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS24920
gene id: 1178516:AWR27_RS24920
uniprot id: A0A1P9X4W3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1178516:AWR27 RS01350
gene id: 1178516:AWR27_RS01350
uniprot id: A0A1P9WRX6
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS06715
gene id: 1178516:AWR27_RS06715
uniprot id: A0A1P9WUG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS11610
gene id: 1178516:AWR27_RS11610
uniprot id: A0A1P9WX28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1178516:AWR27 RS09385
gene id: 1178516:AWR27_RS09385
uniprot id: A0A1P9WVT4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS01255
gene id: 1178516:AWR27_RS01255
uniprot id: A0A1P9WRU2
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS22585
gene id: 1178516:AWR27_RS22585
uniprot id: A0A1P9X2E5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1178516:AWR27 RS02220
gene id: 1178516:AWR27_RS02220
uniprot id: A0A1P9WSB2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1178516:AWR27 RS14660
gene id: 1178516:AWR27_RS14660
uniprot id: A0A1P9WYH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1178516:AWR27 RS12705
gene id: 1178516:AWR27_RS12705
uniprot id: A0A1P9WXK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1178516:AWR27 RS00980
gene id: 1178516:AWR27_RS00980
uniprot id: A0A1P9WRP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1178516:AWR27 RS16110
gene id: 1178516:AWR27_RS16110
uniprot id: A0A1P9WZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1178516:AWR27 RS05605
gene id: 1178516:AWR27_RS05605
uniprot id: A0A1P9WTY4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS06085
gene id: 1178516:AWR27_RS06085
uniprot id: A0A1P9WU62
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1178516:AWR27 RS06295
gene id: 1178516:AWR27_RS06295
uniprot id: A0A1P9WUB2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1178516:AWR27 RS06920
gene id: 1178516:AWR27_RS06920
uniprot id: A0A1P9WUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1178516:AWR27 RS21625
gene id: 1178516:AWR27_RS21625
uniprot id: A0A1P9X1Z3
names: Similarity
messages: Belongs to the Skp family.

1178516:AWR27 RS18665
gene id: 1178516:AWR27_RS18665
uniprot id: A0A1P9X0H0
names: Similarity
messages: Belongs to the UPF0235 family.

1178516:AWR27 RS05955
gene id: 1178516:AWR27_RS05955
uniprot id: A0A1P9WU91
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1178516:AWR27 RS23845
gene id: 1178516:AWR27_RS23845
uniprot id: A0A1P9X336
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1178516:AWR27 RS03435
gene id: 1178516:AWR27_RS03435
uniprot id: A0A1P9WT01
names: Similarity
messages: Belongs to the peptidase S8 family.

1178516:AWR27 RS00220
gene id: 1178516:AWR27_RS00220
uniprot id: A0A1P9WRB8
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

1178516:AWR27 RS02825
gene id: 1178516:AWR27_RS02825
uniprot id: A0A1P9WSL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS18675
gene id: 1178516:AWR27_RS18675
uniprot id: A0A1P9X0G7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1178516:AWR27 RS09690
gene id: 1178516:AWR27_RS09690
uniprot id: A0A1P9WW00
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS09135
gene id: 1178516:AWR27_RS09135
uniprot id: A0A1P9WVR4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS04490
gene id: 1178516:AWR27_RS04490
uniprot id: A0A1P9X3U7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1178516:AWR27 RS07525
gene id: 1178516:AWR27_RS07525
uniprot id: A0A1P9WUV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS16395
gene id: 1178516:AWR27_RS16395
uniprot id: A0A1P9WZD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS03340
gene id: 1178516:AWR27_RS03340
uniprot id: A0A1P9WSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1178516:AWR27 RS17605
gene id: 1178516:AWR27_RS17605
uniprot id: A0A1P9X026
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS18485
gene id: 1178516:AWR27_RS18485
uniprot id: A0A1P9X0E0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1178516:AWR27 RS03235
gene id: 1178516:AWR27_RS03235
uniprot id: A0A1P9WSS9
names: Similarity
messages: Belongs to the DSD1 family.

1178516:AWR27 RS00645
gene id: 1178516:AWR27_RS00645
uniprot id: A0A1P9X3P7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1178516:AWR27 RS08210
gene id: 1178516:AWR27_RS08210
uniprot id: A0A1P9WV69
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS06570
gene id: 1178516:AWR27_RS06570
uniprot id: A0A1P9WUJ6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1178516:AWR27 RS11385
gene id: 1178516:AWR27_RS11385
uniprot id: A0A1P9WWU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1178516:AWR27 RS20685
gene id: 1178516:AWR27_RS20685
uniprot id: A0A1P9X1I7
names: Similarity
messages: Belongs to the TrpC family.

1178516:AWR27 RS09695
gene id: 1178516:AWR27_RS09695
uniprot id: A0A1P9WW01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS01950
gene id: 1178516:AWR27_RS01950
uniprot id: A0A1P9WS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1178516:AWR27 RS03725
gene id: 1178516:AWR27_RS03725
uniprot id: A0A1P9WT19
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS19340
gene id: 1178516:AWR27_RS19340
uniprot id: A0A1P9X0T8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1178516:AWR27 RS09640
gene id: 1178516:AWR27_RS09640
uniprot id: A0A1P9WVZ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1178516:AWR27 RS07170
gene id: 1178516:AWR27_RS07170
uniprot id: A0A1P9WUQ9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS14780
gene id: 1178516:AWR27_RS14780
uniprot id: A0A1P9WYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1178516:AWR27 RS22430
gene id: 1178516:AWR27_RS22430
uniprot id: A0A1P9X2F7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS09990
gene id: 1178516:AWR27_RS09990
uniprot id: A0A1P9WWB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1178516:AWR27 RS03270
gene id: 1178516:AWR27_RS03270
uniprot id: A0A1P9WSY0
names: Similarity
messages: Belongs to the YciI family.

1178516:AWR27 RS21175
gene id: 1178516:AWR27_RS21175
uniprot id: A0A1P9X1Q8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1178516:AWR27 RS15710
gene id: 1178516:AWR27_RS15710
uniprot id: A0A1P9WZ04
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1178516:AWR27 RS02235
gene id: 1178516:AWR27_RS02235
uniprot id: A0A1P9WSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1178516:AWR27 RS12045
gene id: 1178516:AWR27_RS12045
uniprot id: A0A1P9WX94
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS19510
gene id: 1178516:AWR27_RS19510
uniprot id: A0A1P9X0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS09010
gene id: 1178516:AWR27_RS09010
uniprot id: A0A1P9WVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1178516:AWR27 RS09960
gene id: 1178516:AWR27_RS09960
uniprot id: A0A1P9WW38
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19990
gene id: 1178516:AWR27_RS19990
uniprot id: A0A1P9X163
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1178516:AWR27 RS09240
gene id: 1178516:AWR27_RS09240
uniprot id: A0A1P9WVR9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1178516:AWR27 RS14490
gene id: 1178516:AWR27_RS14490
uniprot id: A0A1P9WYF4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1178516:AWR27 RS00530
gene id: 1178516:AWR27_RS00530
uniprot id: A0A1P9WRF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1178516:AWR27 RS06265
gene id: 1178516:AWR27_RS06265
uniprot id: A0A1P9WU88
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1178516:AWR27 RS11010
gene id: 1178516:AWR27_RS11010
uniprot id: A0A1P9WWU6
names: Similarity
messages: Belongs to the peptidase U62 family.

1178516:AWR27 RS17025
gene id: 1178516:AWR27_RS17025
uniprot id: A0A1P9WZM6
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1178516:AWR27 RS00095
gene id: 1178516:AWR27_RS00095
uniprot id: A0A1P9WR93
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1178516:AWR27 RS11990
gene id: 1178516:AWR27_RS11990
uniprot id: A0A1P9X492
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1178516:AWR27 RS00395
gene id: 1178516:AWR27_RS00395
uniprot id: A0A1P9WRF3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1178516:AWR27 RS05535
gene id: 1178516:AWR27_RS05535
uniprot id: A0A1P9WTX3
names: Similarity
messages: Belongs to the sulfatase family.

1178516:AWR27 RS15440
gene id: 1178516:AWR27_RS15440
uniprot id: A0A1P9WYV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1178516:AWR27 RS13580
gene id: 1178516:AWR27_RS13580
uniprot id: A0A1P9WXY7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1178516:AWR27 RS16725
gene id: 1178516:AWR27_RS16725
uniprot id: A0A1P9WZH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1178516:AWR27 RS23850
gene id: 1178516:AWR27_RS23850
uniprot id: A0A1P9X311
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1178516:AWR27 RS13735
gene id: 1178516:AWR27_RS13735
uniprot id: A0A1P9WY13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1178516:AWR27 RS07350
gene id: 1178516:AWR27_RS07350
uniprot id: A0A1P9WUT5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1178516:AWR27 RS17120
gene id: 1178516:AWR27_RS17120
uniprot id: A0A1P9WZT7
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1178516:AWR27 RS21420
gene id: 1178516:AWR27_RS21420
uniprot id: A0A1P9X1U1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1178516:AWR27 RS06555
gene id: 1178516:AWR27_RS06555
uniprot id: A0A1P9WUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1178516:AWR27 RS16425
gene id: 1178516:AWR27_RS16425
uniprot id: A0A1P9WZC3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1178516:AWR27 RS17110
gene id: 1178516:AWR27_RS17110
uniprot id: A0A1P9WZP4
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1178516:AWR27 RS24190
gene id: 1178516:AWR27_RS24190
uniprot id: A0A1P9X370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1178516:AWR27 RS02265
gene id: 1178516:AWR27_RS02265
uniprot id: A0A1P9WSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1178516:AWR27 RS23765
gene id: 1178516:AWR27_RS23765
uniprot id: A0A1P9X333
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1178516:AWR27 RS24640
gene id: 1178516:AWR27_RS24640
uniprot id: A0A1P9X3F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1178516:AWR27 RS18915
gene id: 1178516:AWR27_RS18915
uniprot id: A0A1P9X0Q9
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1178516:AWR27 RS01970
gene id: 1178516:AWR27_RS01970
uniprot id: A0A1P9X3R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS23550
gene id: 1178516:AWR27_RS23550
uniprot id: A0A1P9X2Y8
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS07380
gene id: 1178516:AWR27_RS07380
uniprot id: A0A1P9WUU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1178516:AWR27 RS16525
gene id: 1178516:AWR27_RS16525
uniprot id: A0A1P9WZH0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS02350
gene id: 1178516:AWR27_RS02350
uniprot id: A0A1P9WSF3
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS05365
gene id: 1178516:AWR27_RS05365
uniprot id: A0A1P9WTX1
names: Similarity
messages: Belongs to the Nth/MutY family.

1178516:AWR27 RS00035
gene id: 1178516:AWR27_RS00035
uniprot id: A0A1P9WR92
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS24900
gene id: 1178516:AWR27_RS24900
uniprot id: A0A1P9X3M6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1178516:AWR27 RS22885
gene id: 1178516:AWR27_RS22885
uniprot id: A0A1P9X4V7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1178516:AWR27 RS09025
gene id: 1178516:AWR27_RS09025
uniprot id: A0A1P9WVM9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS12720
gene id: 1178516:AWR27_RS12720
uniprot id: A0A1P9WXH2
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS04480
gene id: 1178516:AWR27_RS04480
uniprot id: A0A1P9WTF4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1178516:AWR27 RS09205
gene id: 1178516:AWR27_RS09205
uniprot id: A0A1P9WVQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS24495
gene id: 1178516:AWR27_RS24495
uniprot id: A0A1P9X3C2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1178516:AWR27 RS10770
gene id: 1178516:AWR27_RS10770
uniprot id: A0A1P9WWI8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1178516:AWR27 RS13375
gene id: 1178516:AWR27_RS13375
uniprot id: A0A1P9WXX0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS22990
gene id: 1178516:AWR27_RS22990
uniprot id: A0A1P9X2Q8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS04820
gene id: 1178516:AWR27_RS04820
uniprot id: A0A1P9WTP2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS21335
gene id: 1178516:AWR27_RS21335
uniprot id: A0A1P9X1U0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1178516:AWR27 RS06145
gene id: 1178516:AWR27_RS06145
uniprot id: A0A1P9WUB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1178516:AWR27 RS02170
gene id: 1178516:AWR27_RS02170
uniprot id: A0A1P9X3T5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1178516:AWR27 RS03190
gene id: 1178516:AWR27_RS03190
uniprot id: A0A1P9WSR3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1178516:AWR27 RS20945
gene id: 1178516:AWR27_RS20945
uniprot id: A0A1P9X1N6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS19960
gene id: 1178516:AWR27_RS19960
uniprot id: A0A1P9X177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1178516:AWR27 RS06510
gene id: 1178516:AWR27_RS06510
uniprot id: A0A1P9WUI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS22055
gene id: 1178516:AWR27_RS22055
uniprot id: A0A1P9X283
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1178516:AWR27 RS07675
gene id: 1178516:AWR27_RS07675
uniprot id: A0A1P9WUY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1178516:AWR27 RS12530
gene id: 1178516:AWR27_RS12530
uniprot id: A0A1P9WXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS09065
gene id: 1178516:AWR27_RS09065
uniprot id: A0A1P9WVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1178516:AWR27 RS19265
gene id: 1178516:AWR27_RS19265
uniprot id: A0A1P9X0T7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1178516:AWR27 RS01935
gene id: 1178516:AWR27_RS01935
uniprot id: A0A1P9WS76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1178516:AWR27 RS19770
gene id: 1178516:AWR27_RS19770
uniprot id: A0A1P9X128
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS02940
gene id: 1178516:AWR27_RS02940
uniprot id: A0A1P9WSP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS07720
gene id: 1178516:AWR27_RS07720
uniprot id: A0A1P9WV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1178516:AWR27 RS01840
gene id: 1178516:AWR27_RS01840
uniprot id: A0A1P9WS40
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1178516:AWR27 RS15600
gene id: 1178516:AWR27_RS15600
uniprot id: A0A1P9WZ17
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1178516:AWR27 RS07835
gene id: 1178516:AWR27_RS07835
uniprot id: A0A1P9WV76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1178516:AWR27 RS20425
gene id: 1178516:AWR27_RS20425
uniprot id: A0A1P9X1E5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1178516:AWR27 RS22945
gene id: 1178516:AWR27_RS22945
uniprot id: A0A1P9X2K7
names: Similarity
messages: Belongs to the NDK family.

1178516:AWR27 RS19505
gene id: 1178516:AWR27_RS19505
uniprot id: A0A1P9X0X4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1178516:AWR27 RS23595
gene id: 1178516:AWR27_RS23595
uniprot id: A0A1P9X2Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1178516:AWR27 RS22035
gene id: 1178516:AWR27_RS22035
uniprot id: A0A1P9X284
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1178516:AWR27 RS19970
gene id: 1178516:AWR27_RS19970
uniprot id: A0A1P9X156
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS14580
gene id: 1178516:AWR27_RS14580
uniprot id: A0A1P9WYF8
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

1178516:AWR27 RS02175
gene id: 1178516:AWR27_RS02175
uniprot id: A0A1P9WSB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1178516:AWR27 RS04555
gene id: 1178516:AWR27_RS04555
uniprot id: A0A1P9WTL0
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS07605
gene id: 1178516:AWR27_RS07605
uniprot id: A0A1P9WV19
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1178516:AWR27 RS07495
gene id: 1178516:AWR27_RS07495
uniprot id: A0A1P9WV09
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS09340
gene id: 1178516:AWR27_RS09340
uniprot id: A0A1P9WVT7
names: Similarity
messages: Belongs to the LOG family.

1178516:AWR27 RS12635
gene id: 1178516:AWR27_RS12635
uniprot id: A0A1P9WXH3
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1178516:AWR27 RS16815
gene id: 1178516:AWR27_RS16815
uniprot id: A0A1P9WZM1
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1178516:AWR27 RS07120
gene id: 1178516:AWR27_RS07120
uniprot id: A0A1P9WUQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1178516:AWR27 RS09860
gene id: 1178516:AWR27_RS09860
uniprot id: A0A1P9WW13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS16840
gene id: 1178516:AWR27_RS16840
uniprot id: A0A1P9X4I1
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS15975
gene id: 1178516:AWR27_RS15975
uniprot id: A0A1P9WZ90
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS17715
gene id: 1178516:AWR27_RS17715
uniprot id: A0A1P9X057
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1178516:AWR27 RS22365
gene id: 1178516:AWR27_RS22365
uniprot id: A0A1P9X2A7
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS11370
gene id: 1178516:AWR27_RS11370
uniprot id: A0A1P9WWV3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1178516:AWR27 RS08710
gene id: 1178516:AWR27_RS08710
uniprot id: A0A1P9WVG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS08060
gene id: 1178516:AWR27_RS08060
uniprot id: A0A1P9WV75
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1178516:AWR27 RS18600
gene id: 1178516:AWR27_RS18600
uniprot id: A0A1P9X0G0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1178516:AWR27 RS16835
gene id: 1178516:AWR27_RS16835
uniprot id: A0A1P9WZP5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1178516:AWR27 RS24420
gene id: 1178516:AWR27_RS24420
uniprot id: A0A1P9X3D2
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS06455
gene id: 1178516:AWR27_RS06455
uniprot id: A0A1P9WUE4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS11425
gene id: 1178516:AWR27_RS11425
uniprot id: A0A1P9WWU5
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS00535
gene id: 1178516:AWR27_RS00535
uniprot id: A0A1P9WRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1178516:AWR27 RS17975
gene id: 1178516:AWR27_RS17975
uniprot id: A0A1P9X048
names: Similarity
messages: Belongs to the DinB family.

1178516:AWR27 RS01895
gene id: 1178516:AWR27_RS01895
uniprot id: A0A1P9WS49
names: Similarity
messages: Belongs to the hyi family.

1178516:AWR27 RS01975
gene id: 1178516:AWR27_RS01975
uniprot id: A0A1P9WS80
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS22890
gene id: 1178516:AWR27_RS22890
uniprot id: A0A1P9X2N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS14590
gene id: 1178516:AWR27_RS14590
uniprot id: A0A1P9WYF0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1178516:AWR27 RS05295
gene id: 1178516:AWR27_RS05295
uniprot id: A0A1P9WTS0
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS22435
gene id: 1178516:AWR27_RS22435
uniprot id: A0A1P9X2D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1178516:AWR27 RS22265
gene id: 1178516:AWR27_RS22265
uniprot id: A0A1P9X2C7
names: Similarity
messages: Belongs to the peptidase S9A family.

1178516:AWR27 RS02200
gene id: 1178516:AWR27_RS02200
uniprot id: A0A1P9WSA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1178516:AWR27 RS21160
gene id: 1178516:AWR27_RS21160
uniprot id: A0A1P9X4Q5
names: Similarity
messages: Belongs to the aspartokinase family.

1178516:AWR27 RS21565
gene id: 1178516:AWR27_RS21565
uniprot id: A0A1P9X1W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1178516:AWR27 RS21145
gene id: 1178516:AWR27_RS21145
uniprot id: A0A1P9X1Q5
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS18560
gene id: 1178516:AWR27_RS18560
uniprot id: A0A1P9X0H6
names: Subcellular Location Annotation
messages: Secreted

1178516:AWR27 RS04260
gene id: 1178516:AWR27_RS04260
uniprot id: A0A1P9WTD1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1178516:AWR27 RS21055
gene id: 1178516:AWR27_RS21055
uniprot id: A0A1P9X1T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1178516:AWR27 RS04240
gene id: 1178516:AWR27_RS04240
uniprot id: A0A1P9WTA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1178516:AWR27 RS02135
gene id: 1178516:AWR27_RS02135
uniprot id: A0A1P9WS85
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1178516:AWR27 RS04830
gene id: 1178516:AWR27_RS04830
uniprot id: A0A1P9WTL5
names: Similarity
messages: Belongs to the peptidase M16 family.

1178516:AWR27 RS00355
gene id: 1178516:AWR27_RS00355
uniprot id: A0A1P9WRC9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1178516:AWR27 RS24525
gene id: 1178516:AWR27_RS24525
uniprot id: A0A1P9X4X4
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1178516:AWR27 RS17445
gene id: 1178516:AWR27_RS17445
uniprot id: A0A1P9WZX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS17810
gene id: 1178516:AWR27_RS17810
uniprot id: A0A1P9X071
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1178516:AWR27 RS13570
gene id: 1178516:AWR27_RS13570
uniprot id: A0A1P9WXW0
names: Subunit
messages: Homodimer.

1178516:AWR27 RS00675
gene id: 1178516:AWR27_RS00675
uniprot id: A0A1P9WRK3
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS15630
gene id: 1178516:AWR27_RS15630
uniprot id: A0A1P9WYZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1178516:AWR27 RS04485
gene id: 1178516:AWR27_RS04485
uniprot id: A0A1P9X3W9
names: Similarity
messages: Belongs to the UPF0758 family.

1178516:AWR27 RS12735
gene id: 1178516:AWR27_RS12735
uniprot id: A0A1P9WXI3
names: Similarity
messages: Belongs to the ParB family.

1178516:AWR27 RS05280
gene id: 1178516:AWR27_RS05280
uniprot id: A0A1P9WTY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS12960
gene id: 1178516:AWR27_RS12960
uniprot id: A0A1P9X4G6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1178516:AWR27 RS00155
gene id: 1178516:AWR27_RS00155
uniprot id: A0A1P9WRA2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1178516:AWR27 RS06485
gene id: 1178516:AWR27_RS06485
uniprot id: A0A1P9WUD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1178516:AWR27 RS06815
gene id: 1178516:AWR27_RS06815
uniprot id: A0A1P9WUJ5
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1178516:AWR27 RS03960
gene id: 1178516:AWR27_RS03960
uniprot id: A0A1P9WT76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1178516:AWR27 RS16480
gene id: 1178516:AWR27_RS16480
uniprot id: A0A1P9WZD3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1178516:AWR27 RS17475
gene id: 1178516:AWR27_RS17475
uniprot id: A0A1P9WZX0
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1178516:AWR27 RS06885
gene id: 1178516:AWR27_RS06885
uniprot id: A0A1P9WUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1178516:AWR27 RS12770
gene id: 1178516:AWR27_RS12770
uniprot id: A0A1P9WXL4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1178516:AWR27 RS03050
gene id: 1178516:AWR27_RS03050
uniprot id: A0A1P9WSQ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1178516:AWR27 RS23860
gene id: 1178516:AWR27_RS23860
uniprot id: A0A1P9X319
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1178516:AWR27 RS24215
gene id: 1178516:AWR27_RS24215
uniprot id: A0A1P9X380
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS14210
gene id: 1178516:AWR27_RS14210
uniprot id: A0A1P9WY83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1178516:AWR27 RS23015
gene id: 1178516:AWR27_RS23015
uniprot id: A0A1P9X2M5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1178516:AWR27 RS10245
gene id: 1178516:AWR27_RS10245
uniprot id: A0A1P9WWA2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1178516:AWR27 RS01335
gene id: 1178516:AWR27_RS01335
uniprot id: A0A1P9WRW3
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS04565
gene id: 1178516:AWR27_RS04565
uniprot id: A0A1P9WTF6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS08440
gene id: 1178516:AWR27_RS08440
uniprot id: A0A1P9WVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1178516:AWR27 RS24345
gene id: 1178516:AWR27_RS24345
uniprot id: A0A1P9X3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1178516:AWR27 RS18370
gene id: 1178516:AWR27_RS18370
uniprot id: A0A1P9X0B2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1178516:AWR27 RS04785
gene id: 1178516:AWR27_RS04785
uniprot id: A0A1P9WTJ6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1178516:AWR27 RS06100
gene id: 1178516:AWR27_RS06100
uniprot id: A0A1P9WU89
names: Similarity
messages: Belongs to the peptidase A31 family.

1178516:AWR27 RS20280
gene id: 1178516:AWR27_RS20280
uniprot id: A0A1P9X1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1178516:AWR27 RS16750
gene id: 1178516:AWR27_RS16750
uniprot id: A0A1P9WZI2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1178516:AWR27 RS07485
gene id: 1178516:AWR27_RS07485
uniprot id: A0A1P9WV04
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS11525
gene id: 1178516:AWR27_RS11525
uniprot id: A0A1P9WX31
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1178516:AWR27 RS12220
gene id: 1178516:AWR27_RS12220
uniprot id: A0A1P9WX84
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1178516:AWR27 RS10130
gene id: 1178516:AWR27_RS10130
uniprot id: A0A1P9WW68
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1178516:AWR27 RS22295
gene id: 1178516:AWR27_RS22295
uniprot id: A0A1P9X2C5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1178516:AWR27 RS19070
gene id: 1178516:AWR27_RS19070
uniprot id: A0A1P9X0P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS07060
gene id: 1178516:AWR27_RS07060
uniprot id: A0A1P9WUP2
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS20060
gene id: 1178516:AWR27_RS20060
uniprot id: A0A1P9X4P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS13125
gene id: 1178516:AWR27_RS13125
uniprot id: A0A1P9WXS7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1178516:AWR27 RS15680
gene id: 1178516:AWR27_RS15680
uniprot id: A0A1P9WZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS11535
gene id: 1178516:AWR27_RS11535
uniprot id: A0A1P9WX04
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1178516:AWR27 RS23770
gene id: 1178516:AWR27_RS23770
uniprot id: A0A1P9X310
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1178516:AWR27 RS15145
gene id: 1178516:AWR27_RS15145
uniprot id: A0A1P9WYQ9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS08195
gene id: 1178516:AWR27_RS08195
uniprot id: A0A1P9WV80
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1178516:AWR27 RS20295
gene id: 1178516:AWR27_RS20295
uniprot id: A0A1P9X1A7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1178516:AWR27 RS23225
gene id: 1178516:AWR27_RS23225
uniprot id: A0A1P9X2S3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS12030
gene id: 1178516:AWR27_RS12030
uniprot id: A0A1P9WX61
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS23310
gene id: 1178516:AWR27_RS23310
uniprot id: A0A1P9X2S1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS21640
gene id: 1178516:AWR27_RS21640
uniprot id: A0A1P9X1Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1178516:AWR27 RS22580
gene id: 1178516:AWR27_RS22580
uniprot id: A0A1P9X2J4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1178516:AWR27 RS16135
gene id: 1178516:AWR27_RS16135
uniprot id: A0A1P9WZA5
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1178516:AWR27 RS17265
gene id: 1178516:AWR27_RS17265
uniprot id: A0A1P9WZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1178516:AWR27 RS13285
gene id: 1178516:AWR27_RS13285
uniprot id: A0A1P9WXV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1178516:AWR27 RS00625
gene id: 1178516:AWR27_RS00625
uniprot id: A0A1P9WRJ0
names: Similarity
messages: Belongs to the UPF0311 family.

1178516:AWR27 RS00040
gene id: 1178516:AWR27_RS00040
uniprot id: A0A1P9WR82
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS16620
gene id: 1178516:AWR27_RS16620
uniprot id: A0A1P9WZG6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1178516:AWR27 RS13690
gene id: 1178516:AWR27_RS13690
uniprot id: A0A1P9WY27
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS08255
gene id: 1178516:AWR27_RS08255
uniprot id: A0A1P9WVA7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1178516:AWR27 RS20880
gene id: 1178516:AWR27_RS20880
uniprot id: A0A1P9X1J5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1178516:AWR27 RS11200
gene id: 1178516:AWR27_RS11200
uniprot id: A0A1P9WWS8
names: Similarity
messages: Belongs to the Dps family.

1178516:AWR27 RS11715
gene id: 1178516:AWR27_RS11715
uniprot id: A0A1P9WX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1178516:AWR27 RS07260
gene id: 1178516:AWR27_RS07260
uniprot id: A0A1P9WUS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1178516:AWR27 RS18120
gene id: 1178516:AWR27_RS18120
uniprot id: A0A1P9X078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1178516:AWR27 RS01955
gene id: 1178516:AWR27_RS01955
uniprot id: A0A1P9WS56
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1178516:AWR27 RS19290
gene id: 1178516:AWR27_RS19290
uniprot id: A0A1P9X0S8
names: Similarity
messages: Belongs to the peptidase S1C family.

1178516:AWR27 RS09370
gene id: 1178516:AWR27_RS09370
uniprot id: A0A1P9WVT2
names: Similarity
messages: Belongs to the peptidase S9C family.

1178516:AWR27 RS20595
gene id: 1178516:AWR27_RS20595
uniprot id: A0A1P9X1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1178516:AWR27 RS08505
gene id: 1178516:AWR27_RS08505
uniprot id: A0A1P9X420
names: Similarity
messages: Belongs to the glutamate synthase family.

1178516:AWR27 RS21185
gene id: 1178516:AWR27_RS21185
uniprot id: A0A1P9X1Q1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1178516:AWR27 RS05545
gene id: 1178516:AWR27_RS05545
uniprot id: A0A1P9WTV8
names: Similarity
messages: Belongs to the sulfatase family.

1178516:AWR27 RS08920
gene id: 1178516:AWR27_RS08920
uniprot id: A0A1P9WVJ9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS02415
gene id: 1178516:AWR27_RS02415
uniprot id: A0A1P9WSD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1178516:AWR27 RS05750
gene id: 1178516:AWR27_RS05750
uniprot id: A0A1P9WTZ4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1178516:AWR27 RS15530
gene id: 1178516:AWR27_RS15530
uniprot id: A0A1P9WYX5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1178516:AWR27 RS13930
gene id: 1178516:AWR27_RS13930
uniprot id: A0A1P9WY33
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1178516:AWR27 RS19040
gene id: 1178516:AWR27_RS19040
uniprot id: A0A1P9X0T6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1178516:AWR27 RS05635
gene id: 1178516:AWR27_RS05635
uniprot id: A0A1P9X3X1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS10700
gene id: 1178516:AWR27_RS10700
uniprot id: A0A1P9WWI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1178516:AWR27 RS10250
gene id: 1178516:AWR27_RS10250
uniprot id: A0A1P9WW96
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1178516:AWR27 RS20985
gene id: 1178516:AWR27_RS20985
uniprot id: A0A1P9X1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1178516:AWR27 RS19560
gene id: 1178516:AWR27_RS19560
uniprot id: A0A1P9X109
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1178516:AWR27 RS06545
gene id: 1178516:AWR27_RS06545
uniprot id: A0A1P9WUE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1178516:AWR27 RS16760
gene id: 1178516:AWR27_RS16760
uniprot id: A0A1P9WZJ9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1178516:AWR27 RS21425
gene id: 1178516:AWR27_RS21425
uniprot id: A0A1P9X1V4
names: Similarity
messages: Belongs to the GARS family.

1178516:AWR27 RS23875
gene id: 1178516:AWR27_RS23875
uniprot id: A0A1P9X339
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1178516:AWR27 RS16255
gene id: 1178516:AWR27_RS16255
uniprot id: A0A1P9WZA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1178516:AWR27 RS20520
gene id: 1178516:AWR27_RS20520
uniprot id: A0A1P9X1I6
names: Similarity
messages: Belongs to the LOG family.

1178516:AWR27 RS18300
gene id: 1178516:AWR27_RS18300
uniprot id: A0A1P9X0B4
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS10650
gene id: 1178516:AWR27_RS10650
uniprot id: A0A1P9X4A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1178516:AWR27 RS14710
gene id: 1178516:AWR27_RS14710
uniprot id: A0A1P9WYJ5
names: Function
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1178516:AWR27 RS01860
gene id: 1178516:AWR27_RS01860
uniprot id: A0A1P9WS45
names: Similarity
messages: Belongs to the NodU/CmcH family.

1178516:AWR27 RS03515
gene id: 1178516:AWR27_RS03515
uniprot id: A0A1P9WSV6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1178516:AWR27 RS23180
gene id: 1178516:AWR27_RS23180
uniprot id: A0A1P9X2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1178516:AWR27 RS02970
gene id: 1178516:AWR27_RS02970
uniprot id: A0A1P9WSN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1178516:AWR27 RS08025
gene id: 1178516:AWR27_RS08025
uniprot id: A0A1P9WV57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS00270
gene id: 1178516:AWR27_RS00270
uniprot id: A0A1P9WRC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1178516:AWR27 RS17315
gene id: 1178516:AWR27_RS17315
uniprot id: A0A1P9WZU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1178516:AWR27 RS06070
gene id: 1178516:AWR27_RS06070
uniprot id: A0A1P9WU67
names: Similarity
messages: Belongs to the HupF/HypC family.

1178516:AWR27 RS14695
gene id: 1178516:AWR27_RS14695
uniprot id: A0A1P9WYH8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1178516:AWR27 RS13555
gene id: 1178516:AWR27_RS13555
uniprot id: A0A1P9X4G9
names: Similarity
messages: Belongs to the peptidase S66 family.

1178516:AWR27 RS22535
gene id: 1178516:AWR27_RS22535
uniprot id: A0A1P9X2D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1178516:AWR27 RS24875
gene id: 1178516:AWR27_RS24875
uniprot id: A0A1P9X3P4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1178516:AWR27 RS05965
gene id: 1178516:AWR27_RS05965
uniprot id: A0A1P9WU36
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1178516:AWR27 RS05930
gene id: 1178516:AWR27_RS05930
uniprot id: A0A1P9WU60
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1178516:AWR27 RS01085
gene id: 1178516:AWR27_RS01085
uniprot id: A0A1P9WRQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1178516:AWR27 RS17915
gene id: 1178516:AWR27_RS17915
uniprot id: A0A1P9X074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1178516:AWR27 RS03730
gene id: 1178516:AWR27_RS03730
uniprot id: A0A1P9WT11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1178516:AWR27 RS17785
gene id: 1178516:AWR27_RS17785
uniprot id: A0A1P9X023
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS05235
gene id: 1178516:AWR27_RS05235
uniprot id: A0A1P9WTR5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1178516:AWR27 RS18845
gene id: 1178516:AWR27_RS18845
uniprot id: A0A1P9X0J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS24030
gene id: 1178516:AWR27_RS24030
uniprot id: A0A1P9X342
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1178516:AWR27 RS05800
gene id: 1178516:AWR27_RS05800
uniprot id: A0A1P9X3X3
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1178516:AWR27 RS24115
gene id: 1178516:AWR27_RS24115
uniprot id: A0A1P9X390
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS11780
gene id: 1178516:AWR27_RS11780
uniprot id: A0A1P9WX02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1178516:AWR27 RS05255
gene id: 1178516:AWR27_RS05255
uniprot id: A0A1P9WTR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1178516:AWR27 RS22660
gene id: 1178516:AWR27_RS22660
uniprot id: A0A1P9X2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1178516:AWR27 RS08610
gene id: 1178516:AWR27_RS08610
uniprot id: A0A1P9WVK9
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS19185
gene id: 1178516:AWR27_RS19185
uniprot id: A0A1P9X0R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1178516:AWR27 RS06315
gene id: 1178516:AWR27_RS06315
uniprot id: A0A1P9WU95
names: Similarity
messages: Belongs to the YjiK family.

1178516:AWR27 RS07905
gene id: 1178516:AWR27_RS07905
uniprot id: A0A1P9WV22
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS17520
gene id: 1178516:AWR27_RS17520
uniprot id: A0A1P9WZX2
names: Similarity
messages: Belongs to the MreC family.

1178516:AWR27 RS00325
gene id: 1178516:AWR27_RS00325
uniprot id: A0A1P9WRD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS03380
gene id: 1178516:AWR27_RS03380
uniprot id: A0A1P9WSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1178516:AWR27 RS09030
gene id: 1178516:AWR27_RS09030
uniprot id: A0A1P9WVM3
names: Subcellular Location Annotation
messages: Cytoplasm

1178516:AWR27 RS22310
gene id: 1178516:AWR27_RS22310
uniprot id: A0A1P9X294
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1178516:AWR27 RS03160
gene id: 1178516:AWR27_RS03160
uniprot id: A0A1P9WSV5
names: Similarity
messages: Belongs to the RecJ family.

1178516:AWR27 RS16740
gene id: 1178516:AWR27_RS16740
uniprot id: A0A1P9WZI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1178516:AWR27 RS05685
gene id: 1178516:AWR27_RS05685
uniprot id: A0A1P9WU01
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1178516:AWR27 RS12795
gene id: 1178516:AWR27_RS12795
uniprot id: A0A1P9WXI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1178516:AWR27 RS21215
gene id: 1178516:AWR27_RS21215
uniprot id: A0A1P9X1T1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1178516:AWR27 RS14295
gene id: 1178516:AWR27_RS14295
uniprot id: A0A1P9WYD8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS17455
gene id: 1178516:AWR27_RS17455
uniprot id: A0A1P9WZV1
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1178516:AWR27 RS21660
gene id: 1178516:AWR27_RS21660
uniprot id: A0A1P9X1Y5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1178516:AWR27 RS23760
gene id: 1178516:AWR27_RS23760
uniprot id: A0A1P9X301
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1178516:AWR27 RS11755
gene id: 1178516:AWR27_RS11755
uniprot id: A0A1P9X4B2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1178516:AWR27 RS12385
gene id: 1178516:AWR27_RS12385
uniprot id: A0A1P9WXJ3
names: Subcellular Location Annotation
messages: Cytoplasm

1178516:AWR27 RS11280
gene id: 1178516:AWR27_RS11280
uniprot id: A0A1P9WWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1178516:AWR27 RS02775
gene id: 1178516:AWR27_RS02775
uniprot id: A0A1P9WSM3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1178516:AWR27 RS02410
gene id: 1178516:AWR27_RS02410
uniprot id: A0A1P9WSG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1178516:AWR27 RS23380
gene id: 1178516:AWR27_RS23380
uniprot id: A0A1P9X2U5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1178516:AWR27 RS23800
gene id: 1178516:AWR27_RS23800
uniprot id: A0A1P9X305
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1178516:AWR27 RS00520
gene id: 1178516:AWR27_RS00520
uniprot id: A0A1P9WRH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1178516:AWR27 RS10740
gene id: 1178516:AWR27_RS10740
uniprot id: A0A1P9WWI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1178516:AWR27 RS19105
gene id: 1178516:AWR27_RS19105
uniprot id: A0A1P9X0T5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1178516:AWR27 RS11000
gene id: 1178516:AWR27_RS11000
uniprot id: A0A1P9WWN7
names: Similarity
messages: Belongs to the peptidase U62 family.

1178516:AWR27 RS22935
gene id: 1178516:AWR27_RS22935
uniprot id: A0A1P9X2P6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1178516:AWR27 RS20360
gene id: 1178516:AWR27_RS20360
uniprot id: A0A1P9X1D6
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1178516:AWR27 RS07795
gene id: 1178516:AWR27_RS07795
uniprot id: A0A1P9WV38
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1178516:AWR27 RS21580
gene id: 1178516:AWR27_RS21580
uniprot id: A0A1P9X1X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1178516:AWR27 RS07255
gene id: 1178516:AWR27_RS07255
uniprot id: A0A1P9X428
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1178516:AWR27 RS14065
gene id: 1178516:AWR27_RS14065
uniprot id: A0A1P9WY82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1178516:AWR27 RS11750
gene id: 1178516:AWR27_RS11750
uniprot id: A0A1P9WWZ3
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1178516:AWR27 RS19030
gene id: 1178516:AWR27_RS19030
uniprot id: A0A1P9X0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1178516:AWR27 RS16415
gene id: 1178516:AWR27_RS16415
uniprot id: A0A1P9WZE7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1178516:AWR27 RS00840
gene id: 1178516:AWR27_RS00840
uniprot id: A0A1P9X3M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1178516:AWR27 RS06890
gene id: 1178516:AWR27_RS06890
uniprot id: A0A1P9WUK7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1178516:AWR27 RS07980
gene id: 1178516:AWR27_RS07980
uniprot id: A0A1P9WV54
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS06375
gene id: 1178516:AWR27_RS06375
uniprot id: A0A1P9WUF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1178516:AWR27 RS06000
gene id: 1178516:AWR27_RS06000
uniprot id: A0A1P9WU54
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1178516:AWR27 RS21540
gene id: 1178516:AWR27_RS21540
uniprot id: A0A1P9X1W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1178516:AWR27 RS17830
gene id: 1178516:AWR27_RS17830
uniprot id: A0A1P9X025
names: Similarity
messages: Belongs to the SusD family.

1178516:AWR27 RS12540
gene id: 1178516:AWR27_RS12540
uniprot id: A0A1P9WXL8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1178516:AWR27 RS01035
gene id: 1178516:AWR27_RS01035
uniprot id: A0A1P9WRP8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1178516:AWR27 RS21120
gene id: 1178516:AWR27_RS21120
uniprot id: A0A1P9X1N8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1178516:AWR27 RS23085
gene id: 1178516:AWR27_RS23085
uniprot id: A0A1P9X2Q9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1178516:AWR27 RS07970
gene id: 1178516:AWR27_RS07970
uniprot id: A0A1P9WV46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1178516:AWR27 RS24040
gene id: 1178516:AWR27_RS24040
uniprot id: A0A1P9X388
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1178516:AWR27 RS05165
gene id: 1178516:AWR27_RS05165
uniprot id: A0A1P9WTQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1178516:AWR27 RS15370
gene id: 1178516:AWR27_RS15370
uniprot id: A0A1P9WYU3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1178516:AWR27 RS20190
gene id: 1178516:AWR27_RS20190
uniprot id: A0A1P9X195
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS18835
gene id: 1178516:AWR27_RS18835
uniprot id: A0A1P9X0K5
names: Subcellular Location Annotation
messages: Membrane

1178516:AWR27 RS05175
gene id: 1178516:AWR27_RS05175
uniprot id: A0A1P9WTQ9
names: Subcellular Location Annotation
messages: Membrane