1176587:A8C56 RS14355
gene id: 1176587:A8C56_RS14355
uniprot id: A0A1A9I385
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1176587:A8C56 RS09735
gene id: 1176587:A8C56_RS09735
uniprot id: A0A1A9I1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

1176587:A8C56 RS06415
gene id: 1176587:A8C56_RS06415
uniprot id: A0A1A9HZ30
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1176587:A8C56 RS22900
gene id: 1176587:A8C56_RS22900
uniprot id: A0A1A9I753
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS04875
gene id: 1176587:A8C56_RS04875
uniprot id: A0A1A9HYF9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1176587:A8C56 RS18390
gene id: 1176587:A8C56_RS18390
uniprot id: A0A1A9I7K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1176587:A8C56 RS11590
gene id: 1176587:A8C56_RS11590
uniprot id: A0A1A9I4C8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1176587:A8C56 RS05540
gene id: 1176587:A8C56_RS05540
uniprot id: A0A1A9HZL6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1176587:A8C56 RS13545
gene id: 1176587:A8C56_RS13545
uniprot id: A0A1A9I5B7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS09600
gene id: 1176587:A8C56_RS09600
uniprot id: A0A1A9I3D4
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1176587:A8C56 RS11500
gene id: 1176587:A8C56_RS11500
uniprot id: A0A1A9I1J6
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1176587:A8C56 RS05220
gene id: 1176587:A8C56_RS05220
uniprot id: A0A1A9I069
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1176587:A8C56 RS14915
gene id: 1176587:A8C56_RS14915
uniprot id: A0A1A9I5X5
names: Similarity
messages: Belongs to the FPG family.

1176587:A8C56 RS09915
gene id: 1176587:A8C56_RS09915
uniprot id: A0A1A9I0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1176587:A8C56 RS15745
gene id: 1176587:A8C56_RS15745
uniprot id: A0A1A9I593
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1176587:A8C56 RS17770
gene id: 1176587:A8C56_RS17770
uniprot id: A0A1A9I4L9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1176587:A8C56 RS00465
gene id: 1176587:A8C56_RS00465
uniprot id: A0A1A9HW65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS20095
gene id: 1176587:A8C56_RS20095
uniprot id: A0A1A9I5L1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1176587:A8C56 RS09000
gene id: 1176587:A8C56_RS09000
uniprot id: A0A1A9I0B2
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS10370
gene id: 1176587:A8C56_RS10370
uniprot id: A0A1A9I438
names: Similarity
messages: Belongs to the GroES chaperonin family.

1176587:A8C56 RS15560
gene id: 1176587:A8C56_RS15560
uniprot id: A0A1A9I8J1
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS12455
gene id: 1176587:A8C56_RS12455
uniprot id: A0A1A9I239
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS21465
gene id: 1176587:A8C56_RS21465
uniprot id: A0A1A9I953
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS06630
gene id: 1176587:A8C56_RS06630
uniprot id: A0A1A9I293
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1176587:A8C56 RS19890
gene id: 1176587:A8C56_RS19890
uniprot id: A0A1A9I5Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1176587:A8C56 RS19190
gene id: 1176587:A8C56_RS19190
uniprot id: A0A1A9I828
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1176587:A8C56 RS06035
gene id: 1176587:A8C56_RS06035
uniprot id: A0A1A9IAZ1
names: Similarity
messages: Belongs to the glutamate synthase family.

1176587:A8C56 RS16850
gene id: 1176587:A8C56_RS16850
uniprot id: A0A1A9I4D3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS19430
gene id: 1176587:A8C56_RS19430
uniprot id: A0A1A9I5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS04530
gene id: 1176587:A8C56_RS04530
uniprot id: A0A1A9I0Y2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS05645
gene id: 1176587:A8C56_RS05645
uniprot id: A0A1A9I1G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS18345
gene id: 1176587:A8C56_RS18345
uniprot id: A0A1A9I7N6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS11535
gene id: 1176587:A8C56_RS11535
uniprot id: A0A1A9I1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1176587:A8C56 RS08740
gene id: 1176587:A8C56_RS08740
uniprot id: A0A1A9I3A7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1176587:A8C56 RS09380
gene id: 1176587:A8C56_RS09380
uniprot id: A0A1A9I3A3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1176587:A8C56 RS21735
gene id: 1176587:A8C56_RS21735
uniprot id: A0A1A9I858
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1176587:A8C56 RS13050
gene id: 1176587:A8C56_RS13050
uniprot id: A0A1A9I380
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS08670
gene id: 1176587:A8C56_RS08670
uniprot id: A0A1A9I2U4
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

1176587:A8C56 RS10920
gene id: 1176587:A8C56_RS10920
uniprot id: A0A1A9I856
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS01810
gene id: 1176587:A8C56_RS01810
uniprot id: A0A1A9HYI2
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1176587:A8C56 RS00365
gene id: 1176587:A8C56_RS00365
uniprot id: A0A1A9HYS9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1176587:A8C56 RS06380
gene id: 1176587:A8C56_RS06380
uniprot id: A0A1A9I250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1176587:A8C56 RS10835
gene id: 1176587:A8C56_RS10835
uniprot id: A0A1A9I401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1176587:A8C56 RS19105
gene id: 1176587:A8C56_RS19105
uniprot id: A0A1A9I543
names: Similarity
messages: Belongs to the peptidase M13 family.

1176587:A8C56 RS18845
gene id: 1176587:A8C56_RS18845
uniprot id: A0A1A9I7S7
names: Similarity
messages: Belongs to the YciI family.

1176587:A8C56 RS07475
gene id: 1176587:A8C56_RS07475
uniprot id: A0A1A9I2B4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1176587:A8C56 RS06705
gene id: 1176587:A8C56_RS06705
uniprot id: A0A1A9HZ74
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1176587:A8C56 RS15020
gene id: 1176587:A8C56_RS15020
uniprot id: A0A1A9I4Y0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS13900
gene id: 1176587:A8C56_RS13900
uniprot id: A0A1A9I2S3
names: Similarity
messages: Belongs to the arginine deiminase family.

1176587:A8C56 RS15335
gene id: 1176587:A8C56_RS15335
uniprot id: A0A1A9I531
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1176587:A8C56 RS00020
gene id: 1176587:A8C56_RS00020
uniprot id: A0A1A9HYL8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1176587:A8C56 RS17980
gene id: 1176587:A8C56_RS17980
uniprot id: A0A1A9I7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1176587:A8C56 RS07375
gene id: 1176587:A8C56_RS07375
uniprot id: A0A1A9HZY0
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS17975
gene id: 1176587:A8C56_RS17975
uniprot id: A0A1A9I6D1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1176587:A8C56 RS22370
gene id: 1176587:A8C56_RS22370
uniprot id: A0A1A9I9H7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1176587:A8C56 RS07490
gene id: 1176587:A8C56_RS07490
uniprot id: A0A1A9I2N9
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

1176587:A8C56 RS07050
gene id: 1176587:A8C56_RS07050
uniprot id: A0A1A9I227
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1176587:A8C56 RS05025
gene id: 1176587:A8C56_RS05025
uniprot id: A0A1A9I7Q0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1176587:A8C56 RS22340
gene id: 1176587:A8C56_RS22340
uniprot id: A0A1A9I6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1176587:A8C56 RS08185
gene id: 1176587:A8C56_RS08185
uniprot id: A0A1A9I2Q5
names: Similarity
messages: Belongs to the UPF0166 family.

1176587:A8C56 RS00670
gene id: 1176587:A8C56_RS00670
uniprot id: A0A1A9HX77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

1176587:A8C56 RS01520
gene id: 1176587:A8C56_RS01520
uniprot id: A0A1A9HWR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1176587:A8C56 RS18955
gene id: 1176587:A8C56_RS18955
uniprot id: A0A1A9I6V4
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS17985
gene id: 1176587:A8C56_RS17985
uniprot id: A0A1A9I7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1176587:A8C56 RS16115
gene id: 1176587:A8C56_RS16115
uniprot id: A0A1A9I3S7
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

1176587:A8C56 RS22430
gene id: 1176587:A8C56_RS22430
uniprot id: A0A1A9I718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS19970
gene id: 1176587:A8C56_RS19970
uniprot id: A0A1A9I7D7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1176587:A8C56 RS11750
gene id: 1176587:A8C56_RS11750
uniprot id: A0A1A9I2J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1176587:A8C56 RS18535
gene id: 1176587:A8C56_RS18535
uniprot id: A0A1A9I4U8
names: Similarity
messages: Belongs to the peptidase C56 family.

1176587:A8C56 RS03350
gene id: 1176587:A8C56_RS03350
uniprot id: A0A1A9HZB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1176587:A8C56 RS23185
gene id: 1176587:A8C56_RS23185
uniprot id: A0A1A9I9U5
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1176587:A8C56 RS03920
gene id: 1176587:A8C56_RS03920
uniprot id: A0A1A9HYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1176587:A8C56 RS07510
gene id: 1176587:A8C56_RS07510
uniprot id: A0A1A9I865
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1176587:A8C56 RS00440
gene id: 1176587:A8C56_RS00440
uniprot id: A0A1A9HWM9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1176587:A8C56 RS06725
gene id: 1176587:A8C56_RS06725
uniprot id: A0A1A9I1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1176587:A8C56 RS11450
gene id: 1176587:A8C56_RS11450
uniprot id: A0A1A9I479
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS09210
gene id: 1176587:A8C56_RS09210
uniprot id: A0A1A9I336
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1176587:A8C56 RS15550
gene id: 1176587:A8C56_RS15550
uniprot id: A0A1A9I656
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS10005
gene id: 1176587:A8C56_RS10005
uniprot id: A0A1A9I180
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS21600
gene id: 1176587:A8C56_RS21600
uniprot id: A0A1A9I6M4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS10965
gene id: 1176587:A8C56_RS10965
uniprot id: A0A1A9I423
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS16240
gene id: 1176587:A8C56_RS16240
uniprot id: A0A1A9I6H5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1176587:A8C56 RS07260
gene id: 1176587:A8C56_RS07260
uniprot id: A0A1A9HZV7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1176587:A8C56 RS08155
gene id: 1176587:A8C56_RS08155
uniprot id: A0A1A9HZZ2
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1176587:A8C56 RS16955
gene id: 1176587:A8C56_RS16955
uniprot id: A0A1A9I5T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1176587:A8C56 RS18265
gene id: 1176587:A8C56_RS18265
uniprot id: A0A1A9I4Q5
names: Similarity
messages: Belongs to the Skp family.

1176587:A8C56 RS21965
gene id: 1176587:A8C56_RS21965
uniprot id: A0A1A9I891
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1176587:A8C56 RS00560
gene id: 1176587:A8C56_RS00560
uniprot id: A0A1A9HX57
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS15680
gene id: 1176587:A8C56_RS15680
uniprot id: A0A1A9I675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1176587:A8C56 RS07255
gene id: 1176587:A8C56_RS07255
uniprot id: A0A1A9I289
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1176587:A8C56 RS11475
gene id: 1176587:A8C56_RS11475
uniprot id: A0A1A9I2F7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS04115
gene id: 1176587:A8C56_RS04115
uniprot id: A0A1A9HY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS11695
gene id: 1176587:A8C56_RS11695
uniprot id: A0A1A9I1K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1176587:A8C56 RS10300
gene id: 1176587:A8C56_RS10300
uniprot id: A0A1A9I3Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1176587:A8C56 RS18755
gene id: 1176587:A8C56_RS18755
uniprot id: A0A1A9I7V3
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS02130
gene id: 1176587:A8C56_RS02130
uniprot id: A0A1A9I057
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1176587:A8C56 RS00990
gene id: 1176587:A8C56_RS00990
uniprot id: A0A1A9HWF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1176587:A8C56 RS12185
gene id: 1176587:A8C56_RS12185
uniprot id: A0A1A9I1V5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS08190
gene id: 1176587:A8C56_RS08190
uniprot id: A0A1A9I0D7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1176587:A8C56 RS08370
gene id: 1176587:A8C56_RS08370
uniprot id: A0A1A9I2P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1176587:A8C56 RS06465
gene id: 1176587:A8C56_RS06465
uniprot id: A0A1A9HZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1176587:A8C56 RS19765
gene id: 1176587:A8C56_RS19765
uniprot id: A0A1A9I8D6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1176587:A8C56 RS08160
gene id: 1176587:A8C56_RS08160
uniprot id: A0A1A9I1M8
names: Similarity
messages: Belongs to the UbiD family.

1176587:A8C56 RS02070
gene id: 1176587:A8C56_RS02070
uniprot id: A0A1A9HZS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS03360
gene id: 1176587:A8C56_RS03360
uniprot id: A0A1A9I094
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1176587:A8C56 RS07630
gene id: 1176587:A8C56_RS07630
uniprot id: A0A1A9HZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS12600
gene id: 1176587:A8C56_RS12600
uniprot id: A0A1A9I4W5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS11310
gene id: 1176587:A8C56_RS11310
uniprot id: A0A1A9I1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS08785
gene id: 1176587:A8C56_RS08785
uniprot id: A0A1A9I8Y7
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS00845
gene id: 1176587:A8C56_RS00845
uniprot id: A0A1A9HZG8
names: Similarity
messages: Belongs to the peptidase C40 family.

1176587:A8C56 RS09285
gene id: 1176587:A8C56_RS09285
uniprot id: A0A1A9I3J7
names: Subcellular Location Annotation
messages: Nucleus

1176587:A8C56 RS01650
gene id: 1176587:A8C56_RS01650
uniprot id: A0A1A9HYF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1176587:A8C56 RS00350
gene id: 1176587:A8C56_RS00350
uniprot id: A0A1A9HW68
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1176587:A8C56 RS02120
gene id: 1176587:A8C56_RS02120
uniprot id: A0A1A9HZT3
names: Similarity
messages: Belongs to the peptidase S66 family.

1176587:A8C56 RS11605
gene id: 1176587:A8C56_RS11605
uniprot id: A0A1A9IB25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1176587:A8C56 RS11875
gene id: 1176587:A8C56_RS11875
uniprot id: A0A1A9I3E6
names: Subcellular Location Annotation
messages: Cytoplasm

1176587:A8C56 RS19130
gene id: 1176587:A8C56_RS19130
uniprot id: A0A1A9I816
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS14380
gene id: 1176587:A8C56_RS14380
uniprot id: A0A1A9I2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1176587:A8C56 RS13760
gene id: 1176587:A8C56_RS13760
uniprot id: A0A1A9I2L3
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1176587:A8C56 RS21650
gene id: 1176587:A8C56_RS21650
uniprot id: A0A1A9I6N4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1176587:A8C56 RS21655
gene id: 1176587:A8C56_RS21655
uniprot id: A0A1A9I9M6
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1176587:A8C56 RS08475
gene id: 1176587:A8C56_RS08475
uniprot id: A0A1A9I023
names: Similarity
messages: Belongs to the SufE family.

1176587:A8C56 RS07370
gene id: 1176587:A8C56_RS07370
uniprot id: A0A1A9I2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS23440
gene id: 1176587:A8C56_RS23440
uniprot id: A0A1A9IAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS10715
gene id: 1176587:A8C56_RS10715
uniprot id: A0A1A9I1I8
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS08685
gene id: 1176587:A8C56_RS08685
uniprot id: A0A1A9I0K3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1176587:A8C56 RS04215
gene id: 1176587:A8C56_RS04215
uniprot id: A0A1A9HXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1176587:A8C56 RS04220
gene id: 1176587:A8C56_RS04220
uniprot id: A0A1A9HZP4
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS03860
gene id: 1176587:A8C56_RS03860
uniprot id: A0A1A9I0L9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1176587:A8C56 RS00330
gene id: 1176587:A8C56_RS00330
uniprot id: A0A1A9HZ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1176587:A8C56 RS23405
gene id: 1176587:A8C56_RS23405
uniprot id: A0A1A9I781
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1176587:A8C56 RS00275
gene id: 1176587:A8C56_RS00275
uniprot id: A0A1A9HX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1176587:A8C56 RS08615
gene id: 1176587:A8C56_RS08615
uniprot id: A0A1A9I2X6
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1176587:A8C56 RS02410
gene id: 1176587:A8C56_RS02410
uniprot id: A0A1A9HYV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1176587:A8C56 RS19690
gene id: 1176587:A8C56_RS19690
uniprot id: A0A1A9I887
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1176587:A8C56 RS01755
gene id: 1176587:A8C56_RS01755
uniprot id: A0A1A9HYG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1176587:A8C56 RS12870
gene id: 1176587:A8C56_RS12870
uniprot id: A0A1A9I2J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1176587:A8C56 RS15345
gene id: 1176587:A8C56_RS15345
uniprot id: A0A1A9I627
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS10240
gene id: 1176587:A8C56_RS10240
uniprot id: A0A1A9I3L4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1176587:A8C56 RS19045
gene id: 1176587:A8C56_RS19045
uniprot id: A0A1A9I533
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

1176587:A8C56 RS04960
gene id: 1176587:A8C56_RS04960
uniprot id: A0A1A9HYU2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1176587:A8C56 RS22505
gene id: 1176587:A8C56_RS22505
uniprot id: A0A1A9I8Z1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1176587:A8C56 RS08945
gene id: 1176587:A8C56_RS08945
uniprot id: A0A1A9I0B8
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS19710
gene id: 1176587:A8C56_RS19710
uniprot id: A0A1A9I902
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1176587:A8C56 RS19055
gene id: 1176587:A8C56_RS19055
uniprot id: A0A1A9I542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS11820
gene id: 1176587:A8C56_RS11820
uniprot id: A0A1A9I879
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1176587:A8C56 RS21960
gene id: 1176587:A8C56_RS21960
uniprot id: A0A1A9I6I7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1176587:A8C56 RS12075
gene id: 1176587:A8C56_RS12075
uniprot id: A0A1A9I2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1176587:A8C56 RS09800
gene id: 1176587:A8C56_RS09800
uniprot id: A0A1A9I0R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1176587:A8C56 RS01805
gene id: 1176587:A8C56_RS01805
uniprot id: A0A1A9HWU0
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1176587:A8C56 RS03195
gene id: 1176587:A8C56_RS03195
uniprot id: A0A1A9I0B1
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1176587:A8C56 RS21695
gene id: 1176587:A8C56_RS21695
uniprot id: A0A1A9I994
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1176587:A8C56 RS22590
gene id: 1176587:A8C56_RS22590
uniprot id: A0A1A9I6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS15355
gene id: 1176587:A8C56_RS15355
uniprot id: A0A1A9I676
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1176587:A8C56 RS20300
gene id: 1176587:A8C56_RS20300
uniprot id: A0A1A9I8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1176587:A8C56 RS18180
gene id: 1176587:A8C56_RS18180
uniprot id: A0A1A9I509
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS06025
gene id: 1176587:A8C56_RS06025
uniprot id: A0A1A9HYW5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1176587:A8C56 RS22140
gene id: 1176587:A8C56_RS22140
uniprot id: A0A1A9I9C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1176587:A8C56 RS12235
gene id: 1176587:A8C56_RS12235
uniprot id: A0A1A9I2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1176587:A8C56 RS01935
gene id: 1176587:A8C56_RS01935
uniprot id: A0A1A9I7Q3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1176587:A8C56 RS06130
gene id: 1176587:A8C56_RS06130
uniprot id: A0A1A9HZW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS17015
gene id: 1176587:A8C56_RS17015
uniprot id: A0A1A9I6V9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1176587:A8C56 RS05020
gene id: 1176587:A8C56_RS05020
uniprot id: A0A1A9HZC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1176587:A8C56 RS15460
gene id: 1176587:A8C56_RS15460
uniprot id: A0A1A9I3C9
names: Similarity
messages: Belongs to the peptidase M16 family.

1176587:A8C56 RS11985
gene id: 1176587:A8C56_RS11985
uniprot id: A0A1A9I1R6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1176587:A8C56 RS02505
gene id: 1176587:A8C56_RS02505
uniprot id: A0A1A9HX87
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS19025
gene id: 1176587:A8C56_RS19025
uniprot id: A0A1A9I5F4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1176587:A8C56 RS11645
gene id: 1176587:A8C56_RS11645
uniprot id: A0A1A9I4E0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1176587:A8C56 RS04300
gene id: 1176587:A8C56_RS04300
uniprot id: A0A1A9I0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1176587:A8C56 RS01055
gene id: 1176587:A8C56_RS01055
uniprot id: A0A1A9IA72
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS01315
gene id: 1176587:A8C56_RS01315
uniprot id: A0A1A9HZ92
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1176587:A8C56 RS03795
gene id: 1176587:A8C56_RS03795
uniprot id: A0A1A9I0G8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1176587:A8C56 RS06440
gene id: 1176587:A8C56_RS06440
uniprot id: A0A1A9I7Z7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1176587:A8C56 RS14740
gene id: 1176587:A8C56_RS14740
uniprot id: A0A1A9I5U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1176587:A8C56 RS11800
gene id: 1176587:A8C56_RS11800
uniprot id: A0A1A9I2K8
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS23720
gene id: 1176587:A8C56_RS23720
uniprot id: A0A1A9IA17
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS23615
gene id: 1176587:A8C56_RS23615
uniprot id: A0A1A9I9Z7
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS05635
gene id: 1176587:A8C56_RS05635
uniprot id: A0A1A9I0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS16895
gene id: 1176587:A8C56_RS16895
uniprot id: A0A1A9I6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1176587:A8C56 RS05320
gene id: 1176587:A8C56_RS05320
uniprot id: A0A1A9HYL7
names: Similarity
messages: Belongs to the AHA1 family.

1176587:A8C56 RS06915
gene id: 1176587:A8C56_RS06915
uniprot id: A0A1A9I2E4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS09885
gene id: 1176587:A8C56_RS09885
uniprot id: A0A1A9I157
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1176587:A8C56 RS14825
gene id: 1176587:A8C56_RS14825
uniprot id: A0A1A9I436
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1176587:A8C56 RS08050
gene id: 1176587:A8C56_RS08050
uniprot id: A0A1A9I2M0
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS22355
gene id: 1176587:A8C56_RS22355
uniprot id: A0A1A9I9G0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1176587:A8C56 RS12860
gene id: 1176587:A8C56_RS12860
uniprot id: A0A1A9I506
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1176587:A8C56 RS03600
gene id: 1176587:A8C56_RS03600
uniprot id: A0A1A9HYL3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1176587:A8C56 RS21460
gene id: 1176587:A8C56_RS21460
uniprot id: A0A1A9I909
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS01465
gene id: 1176587:A8C56_RS01465
uniprot id: A0A1A9I8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS20540
gene id: 1176587:A8C56_RS20540
uniprot id: A0A1A9I8P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS17905
gene id: 1176587:A8C56_RS17905
uniprot id: A0A1A9I4J0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1176587:A8C56 RS10905
gene id: 1176587:A8C56_RS10905
uniprot id: A0A1A9I1L9
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS04585
gene id: 1176587:A8C56_RS04585
uniprot id: A0A1A9I0V9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1176587:A8C56 RS21880
gene id: 1176587:A8C56_RS21880
uniprot id: A0A1A9IC34
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1176587:A8C56 RS16875
gene id: 1176587:A8C56_RS16875
uniprot id: A0A1A9I9I2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS04310
gene id: 1176587:A8C56_RS04310
uniprot id: A0A1A9HYH8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1176587:A8C56 RS04590
gene id: 1176587:A8C56_RS04590
uniprot id: A0A1A9I0Z0
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1176587:A8C56 RS02660
gene id: 1176587:A8C56_RS02660
uniprot id: A0A1A9HXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1176587:A8C56 RS08645
gene id: 1176587:A8C56_RS08645
uniprot id: A0A1A9I053
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1176587:A8C56 RS16400
gene id: 1176587:A8C56_RS16400
uniprot id: A0A1A9I5J5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS17965
gene id: 1176587:A8C56_RS17965
uniprot id: A0A1A9I4K5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1176587:A8C56 RS05150
gene id: 1176587:A8C56_RS05150
uniprot id: A0A1A9I9G8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1176587:A8C56 RS19005
gene id: 1176587:A8C56_RS19005
uniprot id: A0A1A9I6W4
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS08065
gene id: 1176587:A8C56_RS08065
uniprot id: A0A1A9I2Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1176587:A8C56 RS22220
gene id: 1176587:A8C56_RS22220
uniprot id: A0A1A9I9W5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS22800
gene id: 1176587:A8C56_RS22800
uniprot id: A0A1A9I8N2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1176587:A8C56 RS00955
gene id: 1176587:A8C56_RS00955
uniprot id: A0A1A9HWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS04625
gene id: 1176587:A8C56_RS04625
uniprot id: A0A1A9HZV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1176587:A8C56 RS01925
gene id: 1176587:A8C56_RS01925
uniprot id: A0A1A9IAQ4
names: Similarity
messages: Belongs to the peptidase S9C family.

1176587:A8C56 RS12880
gene id: 1176587:A8C56_RS12880
uniprot id: A0A1A9I345
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1176587:A8C56 RS17675
gene id: 1176587:A8C56_RS17675
uniprot id: A0A1A9I779
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS08930
gene id: 1176587:A8C56_RS08930
uniprot id: A0A1A9I178
names: Similarity
messages: Belongs to the AHA1 family.

1176587:A8C56 RS17945
gene id: 1176587:A8C56_RS17945
uniprot id: A0A1A9I7U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1176587:A8C56 RS10405
gene id: 1176587:A8C56_RS10405
uniprot id: A0A1A9I3P7
names: Subcellular Location Annotation
messages: Nucleus

1176587:A8C56 RS11385
gene id: 1176587:A8C56_RS11385
uniprot id: A0A1A9I364
names: Similarity
messages: Belongs to the citrate synthase family.

1176587:A8C56 RS00225
gene id: 1176587:A8C56_RS00225
uniprot id: A0A1A9HWZ6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1176587:A8C56 RS19310
gene id: 1176587:A8C56_RS19310
uniprot id: A0A1A9I8I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1176587:A8C56 RS09770
gene id: 1176587:A8C56_RS09770
uniprot id: A0A1A9I3G4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1176587:A8C56 RS13110
gene id: 1176587:A8C56_RS13110
uniprot id: A0A1A9I5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1176587:A8C56 RS02610
gene id: 1176587:A8C56_RS02610
uniprot id: A0A1A9HXA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1176587:A8C56 RS15575
gene id: 1176587:A8C56_RS15575
uniprot id: A0A1A9I6A9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1176587:A8C56 RS16760
gene id: 1176587:A8C56_RS16760
uniprot id: A0A1A9I4Z8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1176587:A8C56 RS09730
gene id: 1176587:A8C56_RS09730
uniprot id: A0A1A9I3S5
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS20315
gene id: 1176587:A8C56_RS20315
uniprot id: A0A1A9IBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1176587:A8C56 RS15540
gene id: 1176587:A8C56_RS15540
uniprot id: A0A1A9I9F3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS09080
gene id: 1176587:A8C56_RS09080
uniprot id: A0A1A9I317
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1176587:A8C56 RS18805
gene id: 1176587:A8C56_RS18805
uniprot id: A0A1A9I7W2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS06200
gene id: 1176587:A8C56_RS06200
uniprot id: A0A1A9HYZ3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1176587:A8C56 RS18650
gene id: 1176587:A8C56_RS18650
uniprot id: A0A1A9I588
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS23280
gene id: 1176587:A8C56_RS23280
uniprot id: A0A1A9I7B3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1176587:A8C56 RS11395
gene id: 1176587:A8C56_RS11395
uniprot id: A0A1A9I467
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS02590
gene id: 1176587:A8C56_RS02590
uniprot id: A0A1A9HXP3
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1176587:A8C56 RS07995
gene id: 1176587:A8C56_RS07995
uniprot id: A0A1A9I2J3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1176587:A8C56 RS16945
gene id: 1176587:A8C56_RS16945
uniprot id: A0A1A9I425
names: Similarity
messages: Belongs to the barstar family.

1176587:A8C56 RS01900
gene id: 1176587:A8C56_RS01900
uniprot id: A0A1A9HXV0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS01490
gene id: 1176587:A8C56_RS01490
uniprot id: A0A1A9HZC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1176587:A8C56 RS08490
gene id: 1176587:A8C56_RS08490
uniprot id: A0A1A9I1S6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1176587:A8C56 RS20915
gene id: 1176587:A8C56_RS20915
uniprot id: A0A1A9I8V2
names: Similarity
messages: Belongs to the AHA1 family.

1176587:A8C56 RS19870
gene id: 1176587:A8C56_RS19870
uniprot id: A0A1A9I8F5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1176587:A8C56 RS18900
gene id: 1176587:A8C56_RS18900
uniprot id: A0A1A9I7T6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS01800
gene id: 1176587:A8C56_RS01800
uniprot id: A0A1A9HWW7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1176587:A8C56 RS15800
gene id: 1176587:A8C56_RS15800
uniprot id: A0A1A9I9G1
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS07605
gene id: 1176587:A8C56_RS07605
uniprot id: A0A1A9I829
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1176587:A8C56 RS09920
gene id: 1176587:A8C56_RS09920
uniprot id: A0A1A9I0T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1176587:A8C56 RS12460
gene id: 1176587:A8C56_RS12460
uniprot id: A0A1A9I205
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1176587:A8C56 RS18195
gene id: 1176587:A8C56_RS18195
uniprot id: A0A1A9I5N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS16780
gene id: 1176587:A8C56_RS16780
uniprot id: A0A1A9I5R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS11980
gene id: 1176587:A8C56_RS11980
uniprot id: A0A1A9I1Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1176587:A8C56 RS09375
gene id: 1176587:A8C56_RS09375
uniprot id: A0A1A9I398
names: Similarity
messages: Belongs to the peptidase S8 family.

1176587:A8C56 RS19815
gene id: 1176587:A8C56_RS19815
uniprot id: A0A1A9I8E6
names: Similarity
messages: Belongs to the Nth/MutY family.

1176587:A8C56 RS18660
gene id: 1176587:A8C56_RS18660
uniprot id: A0A1A9I5V3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS12790
gene id: 1176587:A8C56_RS12790
uniprot id: A0A1A9I259
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS01825
gene id: 1176587:A8C56_RS01825
uniprot id: A0A1A9HZM7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS14015
gene id: 1176587:A8C56_RS14015
uniprot id: A0A1A9I2U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1176587:A8C56 RS13410
gene id: 1176587:A8C56_RS13410
uniprot id: A0A1A9I596
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS00015
gene id: 1176587:A8C56_RS00015
uniprot id: A0A1A9HYM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1176587:A8C56 RS06510
gene id: 1176587:A8C56_RS06510
uniprot id: A0A1A9I012
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1176587:A8C56 RS08865
gene id: 1176587:A8C56_RS08865
uniprot id: A0A1A9I164
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1176587:A8C56 RS04895
gene id: 1176587:A8C56_RS04895
uniprot id: A0A1A9I110
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1176587:A8C56 RS00655
gene id: 1176587:A8C56_RS00655
uniprot id: A0A1A9HZ25
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1176587:A8C56 RS23315
gene id: 1176587:A8C56_RS23315
uniprot id: A0A1A9I7F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1176587:A8C56 RS00235
gene id: 1176587:A8C56_RS00235
uniprot id: A0A1A9HW47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS23605
gene id: 1176587:A8C56_RS23605
uniprot id: A0A1A9I7A5
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS01115
gene id: 1176587:A8C56_RS01115
uniprot id: A0A1A9HWJ2
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS11865
gene id: 1176587:A8C56_RS11865
uniprot id: A0A1A9I1N5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1176587:A8C56 RS20090
gene id: 1176587:A8C56_RS20090
uniprot id: A0A1A9I5S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1176587:A8C56 RS15535
gene id: 1176587:A8C56_RS15535
uniprot id: A0A1A9I3D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1176587:A8C56 RS12020
gene id: 1176587:A8C56_RS12020
uniprot id: A0A1A9I2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS18130
gene id: 1176587:A8C56_RS18130
uniprot id: A0A1A9I5M6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1176587:A8C56 RS06765
gene id: 1176587:A8C56_RS06765
uniprot id: A0A1A9HZ84
names: Similarity
messages: Belongs to the acylphosphatase family.

1176587:A8C56 RS19125
gene id: 1176587:A8C56_RS19125
uniprot id: A0A1A9I7Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1176587:A8C56 RS15165
gene id: 1176587:A8C56_RS15165
uniprot id: A0A1A9I5Z3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1176587:A8C56 RS10745
gene id: 1176587:A8C56_RS10745
uniprot id: A0A1A9I168
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1176587:A8C56 RS12110
gene id: 1176587:A8C56_RS12110
uniprot id: A0A1A9I4K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1176587:A8C56 RS07980
gene id: 1176587:A8C56_RS07980
uniprot id: A0A1A9HZU3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1176587:A8C56 RS11315
gene id: 1176587:A8C56_RS11315
uniprot id: A0A1A9I1E4
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS13245
gene id: 1176587:A8C56_RS13245
uniprot id: A0A1A9I3B1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1176587:A8C56 RS18910
gene id: 1176587:A8C56_RS18910
uniprot id: A0A1A9I7Y1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS11880
gene id: 1176587:A8C56_RS11880
uniprot id: A0A1A9I4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1176587:A8C56 RS23700
gene id: 1176587:A8C56_RS23700
uniprot id: A0A1A9I7I0
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS08725
gene id: 1176587:A8C56_RS08725
uniprot id: A0A1A9I2Y3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1176587:A8C56 RS10660
gene id: 1176587:A8C56_RS10660
uniprot id: A0A1A9I3W6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS07505
gene id: 1176587:A8C56_RS07505
uniprot id: A0A1A9HZP0
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS16505
gene id: 1176587:A8C56_RS16505
uniprot id: A0A1A9I6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1176587:A8C56 RS05310
gene id: 1176587:A8C56_RS05310
uniprot id: A0A1A9HYN1
names: Similarity
messages: Belongs to the AHA1 family.

1176587:A8C56 RS11550
gene id: 1176587:A8C56_RS11550
uniprot id: A0A1A9I873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1176587:A8C56 RS13450
gene id: 1176587:A8C56_RS13450
uniprot id: A0A1A9I2G1
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS17710
gene id: 1176587:A8C56_RS17710
uniprot id: A0A1A9I5F8
names: Similarity
messages: Belongs to the glutamate synthase family.

1176587:A8C56 RS04510
gene id: 1176587:A8C56_RS04510
uniprot id: A0A1A9HY35
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1176587:A8C56 RS03740
gene id: 1176587:A8C56_RS03740
uniprot id: A0A1A9I0F7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1176587:A8C56 RS04950
gene id: 1176587:A8C56_RS04950
uniprot id: A0A1A9I133
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1176587:A8C56 RS16300
gene id: 1176587:A8C56_RS16300
uniprot id: A0A1A9I6M6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS07200
gene id: 1176587:A8C56_RS07200
uniprot id: A0A1A9I2I6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1176587:A8C56 RS15120
gene id: 1176587:A8C56_RS15120
uniprot id: A0A1A9I3L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1176587:A8C56 RS15955
gene id: 1176587:A8C56_RS15955
uniprot id: A0A1A9I4L2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1176587:A8C56 RS00115
gene id: 1176587:A8C56_RS00115
uniprot id: A0A1A9HW10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1176587:A8C56 RS01915
gene id: 1176587:A8C56_RS01915
uniprot id: A0A1A9HWZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1176587:A8C56 RS04915
gene id: 1176587:A8C56_RS04915
uniprot id: A0A1A9I1H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1176587:A8C56 RS22365
gene id: 1176587:A8C56_RS22365
uniprot id: A0A1A9I9K8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1176587:A8C56 RS00195
gene id: 1176587:A8C56_RS00195
uniprot id: A0A1A9HYQ1
names: Cofactor
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1176587:A8C56 RS03175
gene id: 1176587:A8C56_RS03175
uniprot id: A0A1A9HXH2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1176587:A8C56 RS02150
gene id: 1176587:A8C56_RS02150
uniprot id: A0A1A9HX28
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1176587:A8C56 RS08855
gene id: 1176587:A8C56_RS08855
uniprot id: A0A1A9I0N4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1176587:A8C56 RS05000
gene id: 1176587:A8C56_RS05000
uniprot id: A0A1A9I150
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1176587:A8C56 RS02645
gene id: 1176587:A8C56_RS02645
uniprot id: A0A1A9I0E4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1176587:A8C56 RS05490
gene id: 1176587:A8C56_RS05490
uniprot id: A0A1A9HYP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1176587:A8C56 RS11320
gene id: 1176587:A8C56_RS11320
uniprot id: A0A1A9I1F9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS05935
gene id: 1176587:A8C56_RS05935
uniprot id: A0A1A9HZT0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS23290
gene id: 1176587:A8C56_RS23290
uniprot id: A0A1A9I762
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1176587:A8C56 RS21750
gene id: 1176587:A8C56_RS21750
uniprot id: A0A1A9I969
names: Similarity
messages: Belongs to the ComB family.

1176587:A8C56 RS21610
gene id: 1176587:A8C56_RS21610
uniprot id: A0A1A9I7A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1176587:A8C56 RS12155
gene id: 1176587:A8C56_RS12155
uniprot id: A0A1A9I4M5
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS11710
gene id: 1176587:A8C56_RS11710
uniprot id: A0A1A9I3B7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1176587:A8C56 RS06850
gene id: 1176587:A8C56_RS06850
uniprot id: A0A1A9HZN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1176587:A8C56 RS15470
gene id: 1176587:A8C56_RS15470
uniprot id: A0A1A9I645
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1176587:A8C56 RS02620
gene id: 1176587:A8C56_RS02620
uniprot id: A0A1A9HYZ6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS15740
gene id: 1176587:A8C56_RS15740
uniprot id: A0A1A9I3H3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS02450
gene id: 1176587:A8C56_RS02450
uniprot id: A0A1A9HX78
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS12160
gene id: 1176587:A8C56_RS12160
uniprot id: A0A1A9I4L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS07525
gene id: 1176587:A8C56_RS07525
uniprot id: A0A1A9I1B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1176587:A8C56 RS11410
gene id: 1176587:A8C56_RS11410
uniprot id: A0A1A9IBC9
names: Similarity
messages: Belongs to the serpin family.

1176587:A8C56 RS05850
gene id: 1176587:A8C56_RS05850
uniprot id: A0A1A9I1X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1176587:A8C56 RS00935
gene id: 1176587:A8C56_RS00935
uniprot id: A0A1A9HZ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1176587:A8C56 RS02010
gene id: 1176587:A8C56_RS02010
uniprot id: A0A1A9HZR4
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

1176587:A8C56 RS00960
gene id: 1176587:A8C56_RS00960
uniprot id: A0A1A9HZJ0
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS08260
gene id: 1176587:A8C56_RS08260
uniprot id: A0A1A9I328
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1176587:A8C56 RS19325
gene id: 1176587:A8C56_RS19325
uniprot id: A0A1A9I587
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1176587:A8C56 RS04415
gene id: 1176587:A8C56_RS04415
uniprot id: A0A1A9I0W2
names: Similarity
messages: Belongs to the AHA1 family.

1176587:A8C56 RS18510
gene id: 1176587:A8C56_RS18510
uniprot id: A0A1A9I7R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1176587:A8C56 RS19015
gene id: 1176587:A8C56_RS19015
uniprot id: A0A1A9I7X3
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1176587:A8C56 RS11425
gene id: 1176587:A8C56_RS11425
uniprot id: A0A1A9I2E8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1176587:A8C56 RS07085
gene id: 1176587:A8C56_RS07085
uniprot id: A0A1A9I0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS10000
gene id: 1176587:A8C56_RS10000
uniprot id: A0A1A9IAX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1176587:A8C56 RS03785
gene id: 1176587:A8C56_RS03785
uniprot id: A0A1A9HXR7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1176587:A8C56 RS22440
gene id: 1176587:A8C56_RS22440
uniprot id: A0A1A9I7R6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS10680
gene id: 1176587:A8C56_RS10680
uniprot id: A0A1A9I188
names: Similarity
messages: Belongs to the aspartokinase family.

1176587:A8C56 RS13300
gene id: 1176587:A8C56_RS13300
uniprot id: A0A1A9I8B8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS00405
gene id: 1176587:A8C56_RS00405
uniprot id: A0A1A9HW78
names: Similarity
messages: Belongs to the SCO1/2 family.

1176587:A8C56 RS05245
gene id: 1176587:A8C56_RS05245
uniprot id: A0A1A9I1N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1176587:A8C56 RS21415
gene id: 1176587:A8C56_RS21415
uniprot id: A0A1A9I975
names: Similarity
messages: Belongs to the DEAD box helicase family.

1176587:A8C56 RS11140
gene id: 1176587:A8C56_RS11140
uniprot id: A0A1A9I422
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS15195
gene id: 1176587:A8C56_RS15195
uniprot id: A0A1A9I493
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1176587:A8C56 RS17745
gene id: 1176587:A8C56_RS17745
uniprot id: A0A1A9I794
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1176587:A8C56 RS07435
gene id: 1176587:A8C56_RS07435
uniprot id: A0A1A9I0H2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1176587:A8C56 RS15645
gene id: 1176587:A8C56_RS15645
uniprot id: A0A1A9I6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1176587:A8C56 RS07395
gene id: 1176587:A8C56_RS07395
uniprot id: A0A1A9HZJ1
names: Similarity
messages: Belongs to the universal stress protein A family.

1176587:A8C56 RS09500
gene id: 1176587:A8C56_RS09500
uniprot id: A0A1A9I3N9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1176587:A8C56 RS22235
gene id: 1176587:A8C56_RS22235
uniprot id: A0A1A9I6L7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS05015
gene id: 1176587:A8C56_RS05015
uniprot id: A0A1A9I1J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1176587:A8C56 RS16485
gene id: 1176587:A8C56_RS16485
uniprot id: A0A1A9I3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1176587:A8C56 RS15245
gene id: 1176587:A8C56_RS15245
uniprot id: A0A1A9I3N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1176587:A8C56 RS19980
gene id: 1176587:A8C56_RS19980
uniprot id: A0A1A9I8G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1176587:A8C56 RS21570
gene id: 1176587:A8C56_RS21570
uniprot id: A0A1A9I6B5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1176587:A8C56 RS16570
gene id: 1176587:A8C56_RS16570
uniprot id: A0A1A9I6M9
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1176587:A8C56 RS08520
gene id: 1176587:A8C56_RS08520
uniprot id: A0A1A9I106
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1176587:A8C56 RS22870
gene id: 1176587:A8C56_RS22870
uniprot id: A0A1A9I9U1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1176587:A8C56 RS10750
gene id: 1176587:A8C56_RS10750
uniprot id: A0A1A9I2W5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1176587:A8C56 RS16705
gene id: 1176587:A8C56_RS16705
uniprot id: A0A1A9I4Y7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1176587:A8C56 RS16770
gene id: 1176587:A8C56_RS16770
uniprot id: A0A1A9I3Z7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1176587:A8C56 RS02310
gene id: 1176587:A8C56_RS02310
uniprot id: A0A1A9HXK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1176587:A8C56 RS02560
gene id: 1176587:A8C56_RS02560
uniprot id: A0A1A9HX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS08145
gene id: 1176587:A8C56_RS08145
uniprot id: A0A1A9I005
names: Similarity
messages: Belongs to the universal stress protein A family.

1176587:A8C56 RS16265
gene id: 1176587:A8C56_RS16265
uniprot id: A0A1A9I3V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1176587:A8C56 RS23660
gene id: 1176587:A8C56_RS23660
uniprot id: A0A1A9I7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS00685
gene id: 1176587:A8C56_RS00685
uniprot id: A0A1A9HWA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS02110
gene id: 1176587:A8C56_RS02110
uniprot id: A0A1A9HZN3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS02215
gene id: 1176587:A8C56_RS02215
uniprot id: A0A1A9HX17
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS05705
gene id: 1176587:A8C56_RS05705
uniprot id: A0A1A9I1I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1176587:A8C56 RS15115
gene id: 1176587:A8C56_RS15115
uniprot id: A0A1A9I638
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1176587:A8C56 RS19050
gene id: 1176587:A8C56_RS19050
uniprot id: A0A1A9IBJ7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1176587:A8C56 RS16230
gene id: 1176587:A8C56_RS16230
uniprot id: A0A1A9I5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1176587:A8C56 RS17625
gene id: 1176587:A8C56_RS17625
uniprot id: A0A1A9I768
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1176587:A8C56 RS03985
gene id: 1176587:A8C56_RS03985
uniprot id: A0A1A9HXZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS17125
gene id: 1176587:A8C56_RS17125
uniprot id: A0A1A9I5X9
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS22360
gene id: 1176587:A8C56_RS22360
uniprot id: A0A1A9I998
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1176587:A8C56 RS03070
gene id: 1176587:A8C56_RS03070
uniprot id: A0A1A9I048
names: Similarity
messages: Belongs to the glutamine synthetase family.

1176587:A8C56 RS20350
gene id: 1176587:A8C56_RS20350
uniprot id: A0A1A9I8I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS05785
gene id: 1176587:A8C56_RS05785
uniprot id: A0A1A9I7S1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1176587:A8C56 RS19475
gene id: 1176587:A8C56_RS19475
uniprot id: A0A1A9I8M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1176587:A8C56 RS04200
gene id: 1176587:A8C56_RS04200
uniprot id: A0A1A9HY31
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS04385
gene id: 1176587:A8C56_RS04385
uniprot id: A0A1A9HY12
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS15125
gene id: 1176587:A8C56_RS15125
uniprot id: A0A1A9I6G1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1176587:A8C56 RS20380
gene id: 1176587:A8C56_RS20380
uniprot id: A0A1A9I6R4
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS11575
gene id: 1176587:A8C56_RS11575
uniprot id: A0A1A9I394
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1176587:A8C56 RS21075
gene id: 1176587:A8C56_RS21075
uniprot id: A0A1A9I7W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1176587:A8C56 RS13400
gene id: 1176587:A8C56_RS13400
uniprot id: A0A1A9I461
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS08860
gene id: 1176587:A8C56_RS08860
uniprot id: A0A1A9I3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1176587:A8C56 RS18515
gene id: 1176587:A8C56_RS18515
uniprot id: A0A1A9I568
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1176587:A8C56 RS03110
gene id: 1176587:A8C56_RS03110
uniprot id: A0A1A9HXG4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS14730
gene id: 1176587:A8C56_RS14730
uniprot id: A0A1A9I313
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS09130
gene id: 1176587:A8C56_RS09130
uniprot id: A0A1A9I237
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1176587:A8C56 RS09990
gene id: 1176587:A8C56_RS09990
uniprot id: A0A1A9I3L0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1176587:A8C56 RS06560
gene id: 1176587:A8C56_RS06560
uniprot id: A0A1A9I021
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS17360
gene id: 1176587:A8C56_RS17360
uniprot id: A0A1A9I767
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1176587:A8C56 RS11565
gene id: 1176587:A8C56_RS11565
uniprot id: A0A1A9I1K3
names: Similarity
messages: Belongs to the FGGY kinase family.

1176587:A8C56 RS03605
gene id: 1176587:A8C56_RS03605
uniprot id: A0A1A9HXS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1176587:A8C56 RS11855
gene id: 1176587:A8C56_RS11855
uniprot id: A0A1A9I2L8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1176587:A8C56 RS05880
gene id: 1176587:A8C56_RS05880
uniprot id: A0A1A9I0H5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1176587:A8C56 RS10765
gene id: 1176587:A8C56_RS10765
uniprot id: A0A1A9I3Z0
names: Similarity
messages: Belongs to the peptidase M1 family.

1176587:A8C56 RS07520
gene id: 1176587:A8C56_RS07520
uniprot id: A0A1A9HZL8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS07250
gene id: 1176587:A8C56_RS07250
uniprot id: A0A1A9I274
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS16975
gene id: 1176587:A8C56_RS16975
uniprot id: A0A1A9I702
names: Similarity
messages: Belongs to the ParB family.

1176587:A8C56 RS08235
gene id: 1176587:A8C56_RS08235
uniprot id: A0A1A9I1N8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1176587:A8C56 RS11835
gene id: 1176587:A8C56_RS11835
uniprot id: A0A1A9I4G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1176587:A8C56 RS12415
gene id: 1176587:A8C56_RS12415
uniprot id: A0A1A9I201
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS02535
gene id: 1176587:A8C56_RS02535
uniprot id: A0A1A9HZZ8
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS15310
gene id: 1176587:A8C56_RS15310
uniprot id: A0A1A9I6J0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1176587:A8C56 RS14625
gene id: 1176587:A8C56_RS14625
uniprot id: A0A1A9I8F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1176587:A8C56 RS01790
gene id: 1176587:A8C56_RS01790
uniprot id: A0A1A9HXS0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1176587:A8C56 RS08605
gene id: 1176587:A8C56_RS08605
uniprot id: A0A1A9I2T7
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS23695
gene id: 1176587:A8C56_RS23695
uniprot id: A0A1A9I8A8
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS17610
gene id: 1176587:A8C56_RS17610
uniprot id: A0A1A9I4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1176587:A8C56 RS23180
gene id: 1176587:A8C56_RS23180
uniprot id: A0A1A9I9Z1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1176587:A8C56 RS01765
gene id: 1176587:A8C56_RS01765
uniprot id: A0A1A9HZI2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS25100
gene id: 1176587:A8C56_RS25100
uniprot id: A0A1A9I3I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1176587:A8C56 RS09710
gene id: 1176587:A8C56_RS09710
uniprot id: A0A1A9I3G1
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS13595
gene id: 1176587:A8C56_RS13595
uniprot id: A0A1A9I2H8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS08965
gene id: 1176587:A8C56_RS08965
uniprot id: A0A1A9I333
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1176587:A8C56 RS19245
gene id: 1176587:A8C56_RS19245
uniprot id: A0A1A9I841
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS14270
gene id: 1176587:A8C56_RS14270
uniprot id: A0A1A9I2T5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS04305
gene id: 1176587:A8C56_RS04305
uniprot id: A0A1A9I0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1176587:A8C56 RS04100
gene id: 1176587:A8C56_RS04100
uniprot id: A0A1A9HYF0
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS17350
gene id: 1176587:A8C56_RS17350
uniprot id: A0A1A9I720
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS15025
gene id: 1176587:A8C56_RS15025
uniprot id: A0A1A9I5X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1176587:A8C56 RS01785
gene id: 1176587:A8C56_RS01785
uniprot id: A0A1A9HZY3
names: Similarity
messages: Belongs to the fabD family.

1176587:A8C56 RS05395
gene id: 1176587:A8C56_RS05395
uniprot id: A0A1A9I0A0
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS03770
gene id: 1176587:A8C56_RS03770
uniprot id: A0A1A9HXV2
names: Similarity
messages: Belongs to the DinB family.

1176587:A8C56 RS10830
gene id: 1176587:A8C56_RS10830
uniprot id: A0A1A9IBA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1176587:A8C56 RS06305
gene id: 1176587:A8C56_RS06305
uniprot id: A0A1A9I242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS16315
gene id: 1176587:A8C56_RS16315
uniprot id: A0A1A9I4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1176587:A8C56 RS02515
gene id: 1176587:A8C56_RS02515
uniprot id: A0A1A9HX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1176587:A8C56 RS16940
gene id: 1176587:A8C56_RS16940
uniprot id: A0A1A9I474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

1176587:A8C56 RS00645
gene id: 1176587:A8C56_RS00645
uniprot id: A0A1A9HYX8
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS04495
gene id: 1176587:A8C56_RS04495
uniprot id: A0A1A9HZ24
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS02160
gene id: 1176587:A8C56_RS02160
uniprot id: A0A1A9HX07
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS06140
gene id: 1176587:A8C56_RS06140
uniprot id: A0A1A9HYY3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS21710
gene id: 1176587:A8C56_RS21710
uniprot id: A0A1A9I9N6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS05725
gene id: 1176587:A8C56_RS05725
uniprot id: A0A1A9HYU3
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS09310
gene id: 1176587:A8C56_RS09310
uniprot id: A0A1A9I0H6
names: Similarity
messages: Belongs to the peptidase C1 family.

1176587:A8C56 RS02200
gene id: 1176587:A8C56_RS02200
uniprot id: A0A1A9HXZ8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1176587:A8C56 RS20615
gene id: 1176587:A8C56_RS20615
uniprot id: A0A1A9I968
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS14385
gene id: 1176587:A8C56_RS14385
uniprot id: A0A1A9I4M4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1176587:A8C56 RS23115
gene id: 1176587:A8C56_RS23115
uniprot id: A0A1A9I8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1176587:A8C56 RS23650
gene id: 1176587:A8C56_RS23650
uniprot id: A0A1A9I7H0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS08810
gene id: 1176587:A8C56_RS08810
uniprot id: A0A1A9I154
names: Similarity
messages: Belongs to the fructosamine kinase family.

1176587:A8C56 RS16045
gene id: 1176587:A8C56_RS16045
uniprot id: A0A1A9I3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1176587:A8C56 RS22135
gene id: 1176587:A8C56_RS22135
uniprot id: A0A1A9I8C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1176587:A8C56 RS08535
gene id: 1176587:A8C56_RS08535
uniprot id: A0A1A9I032
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1176587:A8C56 RS23690
gene id: 1176587:A8C56_RS23690
uniprot id: A0A1A9IAI7
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS10290
gene id: 1176587:A8C56_RS10290
uniprot id: A0A1A9I2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS14810
gene id: 1176587:A8C56_RS14810
uniprot id: A0A1A9IB27
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1176587:A8C56 RS10475
gene id: 1176587:A8C56_RS10475
uniprot id: A0A1A9I3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1176587:A8C56 RS08510
gene id: 1176587:A8C56_RS08510
uniprot id: A0A1A9I0I1
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1176587:A8C56 RS23170
gene id: 1176587:A8C56_RS23170
uniprot id: A0A1A9I8U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1176587:A8C56 RS04015
gene id: 1176587:A8C56_RS04015
uniprot id: A0A1A9I7M9
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS20010
gene id: 1176587:A8C56_RS20010
uniprot id: A0A1A9I6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1176587:A8C56 RS01265
gene id: 1176587:A8C56_RS01265
uniprot id: A0A1A9HZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS00105
gene id: 1176587:A8C56_RS00105
uniprot id: A0A1A9HW26
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS04365
gene id: 1176587:A8C56_RS04365
uniprot id: A0A1A9I177
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1176587:A8C56 RS17140
gene id: 1176587:A8C56_RS17140
uniprot id: A0A1A9I6Z0
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS02760
gene id: 1176587:A8C56_RS02760
uniprot id: A0A1A9I0G5
names: Similarity
messages: Belongs to the GSP E family.

1176587:A8C56 RS00620
gene id: 1176587:A8C56_RS00620
uniprot id: A0A1A9HX67
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1176587:A8C56 RS16490
gene id: 1176587:A8C56_RS16490
uniprot id: A0A1A9I3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1176587:A8C56 RS09660
gene id: 1176587:A8C56_RS09660
uniprot id: A0A1A9I3E4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS15430
gene id: 1176587:A8C56_RS15430
uniprot id: A0A1A9I691
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1176587:A8C56 RS03325
gene id: 1176587:A8C56_RS03325
uniprot id: A0A1A9I0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS13355
gene id: 1176587:A8C56_RS13355
uniprot id: A0A1A9I2S7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1176587:A8C56 RS17825
gene id: 1176587:A8C56_RS17825
uniprot id: A0A1A9I4V4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1176587:A8C56 RS00165
gene id: 1176587:A8C56_RS00165
uniprot id: A0A1A9HWY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1176587:A8C56 RS17605
gene id: 1176587:A8C56_RS17605
uniprot id: A0A1A9I8L7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1176587:A8C56 RS18675
gene id: 1176587:A8C56_RS18675
uniprot id: A0A1A9I4X6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1176587:A8C56 RS01320
gene id: 1176587:A8C56_RS01320
uniprot id: A0A1A9HZ93
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1176587:A8C56 RS13170
gene id: 1176587:A8C56_RS13170
uniprot id: A0A1A9I5G7
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS13645
gene id: 1176587:A8C56_RS13645
uniprot id: A0A1A9I2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1176587:A8C56 RS18055
gene id: 1176587:A8C56_RS18055
uniprot id: A0A1A9I7J2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1176587:A8C56 RS13610
gene id: 1176587:A8C56_RS13610
uniprot id: A0A1A9I598
names: Similarity
messages: Belongs to the TPP enzyme family.

1176587:A8C56 RS13040
gene id: 1176587:A8C56_RS13040
uniprot id: A0A1A9I5E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1176587:A8C56 RS04420
gene id: 1176587:A8C56_RS04420
uniprot id: A0A1A9HYJ8
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS07035
gene id: 1176587:A8C56_RS07035
uniprot id: A0A1A9HZD4
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

1176587:A8C56 RS15640
gene id: 1176587:A8C56_RS15640
uniprot id: A0A1A9I3U1
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1176587:A8C56 RS01010
gene id: 1176587:A8C56_RS01010
uniprot id: A0A1A9HZ86
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1176587:A8C56 RS18380
gene id: 1176587:A8C56_RS18380
uniprot id: A0A1A9I6J7
names: Subcellular Location Annotation
messages: Cytoplasm

1176587:A8C56 RS13690
gene id: 1176587:A8C56_RS13690
uniprot id: A0A1A9I5P8
names: Similarity
messages: Belongs to the NodU/CmcH family.

1176587:A8C56 RS09110
gene id: 1176587:A8C56_RS09110
uniprot id: A0A1A9I0G4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1176587:A8C56 RS06815
gene id: 1176587:A8C56_RS06815
uniprot id: A0A1A9HZB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1176587:A8C56 RS20450
gene id: 1176587:A8C56_RS20450
uniprot id: A0A1A9I5R5
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1176587:A8C56 RS23245
gene id: 1176587:A8C56_RS23245
uniprot id: A0A1A9I9U4
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS05215
gene id: 1176587:A8C56_RS05215
uniprot id: A0A1A9IAK8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1176587:A8C56 RS24640
gene id: 1176587:A8C56_RS24640
uniprot id: A0A1A9HZH5
names: Similarity
messages: Belongs to the AHA1 family.

1176587:A8C56 RS10645
gene id: 1176587:A8C56_RS10645
uniprot id: A0A1A9I2U5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1176587:A8C56 RS00540
gene id: 1176587:A8C56_RS00540
uniprot id: A0A1A9HZ10
names: Similarity
messages: Belongs to the UPF0175 family.

1176587:A8C56 RS04185
gene id: 1176587:A8C56_RS04185
uniprot id: A0A1A9HYF6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS05115
gene id: 1176587:A8C56_RS05115
uniprot id: A0A1A9HYX2
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS16470
gene id: 1176587:A8C56_RS16470
uniprot id: A0A1A9I466
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1176587:A8C56 RS16410
gene id: 1176587:A8C56_RS16410
uniprot id: A0A1A9I6K5
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS03700
gene id: 1176587:A8C56_RS03700
uniprot id: A0A1A9HY73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1176587:A8C56 RS15780
gene id: 1176587:A8C56_RS15780
uniprot id: A0A1A9I3M6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1176587:A8C56 RS00690
gene id: 1176587:A8C56_RS00690
uniprot id: A0A1A9HXZ0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS11175
gene id: 1176587:A8C56_RS11175
uniprot id: A0A1A9I1G6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS12260
gene id: 1176587:A8C56_RS12260
uniprot id: A0A1A9I1X4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1176587:A8C56 RS11905
gene id: 1176587:A8C56_RS11905
uniprot id: A0A1A9I4U9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS15825
gene id: 1176587:A8C56_RS15825
uniprot id: A0A1A9I6S0
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS05405
gene id: 1176587:A8C56_RS05405
uniprot id: A0A1A9I1A3
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS13510
gene id: 1176587:A8C56_RS13510
uniprot id: A0A1A9I2H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1176587:A8C56 RS01330
gene id: 1176587:A8C56_RS01330
uniprot id: A0A1A9HX25
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1176587:A8C56 RS05515
gene id: 1176587:A8C56_RS05515
uniprot id: A0A1A9I7Q9
names: Similarity
messages: Belongs to the AHA1 family.

1176587:A8C56 RS20740
gene id: 1176587:A8C56_RS20740
uniprot id: A0A1A9I8W3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1176587:A8C56 RS01795
gene id: 1176587:A8C56_RS01795
uniprot id: A0A1A9HWW4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1176587:A8C56 RS08165
gene id: 1176587:A8C56_RS08165
uniprot id: A0A1A9I2M1
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

1176587:A8C56 RS21400
gene id: 1176587:A8C56_RS21400
uniprot id: A0A1A9I9I9
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS02045
gene id: 1176587:A8C56_RS02045
uniprot id: A0A1A9HX08
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1176587:A8C56 RS10705
gene id: 1176587:A8C56_RS10705
uniprot id: A0A1A9I3Y0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS05070
gene id: 1176587:A8C56_RS05070
uniprot id: A0A1A9I1K6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS14800
gene id: 1176587:A8C56_RS14800
uniprot id: A0A1A9I5V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1176587:A8C56 RS16845
gene id: 1176587:A8C56_RS16845
uniprot id: A0A1A9I6X8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1176587:A8C56 RS05885
gene id: 1176587:A8C56_RS05885
uniprot id: A0A1A9I1I4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1176587:A8C56 RS06625
gene id: 1176587:A8C56_RS06625
uniprot id: A0A1A9IAK2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS08210
gene id: 1176587:A8C56_RS08210
uniprot id: A0A1A9I0V6
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS08455
gene id: 1176587:A8C56_RS08455
uniprot id: A0A1A9I0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1176587:A8C56 RS21730
gene id: 1176587:A8C56_RS21730
uniprot id: A0A1A9I6E8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS17500
gene id: 1176587:A8C56_RS17500
uniprot id: A0A1A9I4C5
names: Similarity
messages: Belongs to the HSP15 family.

1176587:A8C56 RS09740
gene id: 1176587:A8C56_RS09740
uniprot id: A0A1A9I0S6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1176587:A8C56 RS23785
gene id: 1176587:A8C56_RS23785
uniprot id: A0A1A9IA40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1176587:A8C56 RS20200
gene id: 1176587:A8C56_RS20200
uniprot id: A0A1A9I8Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1176587:A8C56 RS12765
gene id: 1176587:A8C56_RS12765
uniprot id: A0A1A9I2H6
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1176587:A8C56 RS09115
gene id: 1176587:A8C56_RS09115
uniprot id: A0A1A9IAV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1176587:A8C56 RS08570
gene id: 1176587:A8C56_RS08570
uniprot id: A0A1A9I375
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS00325
gene id: 1176587:A8C56_RS00325
uniprot id: A0A1A9HWL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1176587:A8C56 RS08590
gene id: 1176587:A8C56_RS08590
uniprot id: A0A1A9I043
names: Similarity
messages: Belongs to the peptidase S41A family.

1176587:A8C56 RS11400
gene id: 1176587:A8C56_RS11400
uniprot id: A0A1A9I4A1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS11745
gene id: 1176587:A8C56_RS11745
uniprot id: A0A1A9I4S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1176587:A8C56 RS01995
gene id: 1176587:A8C56_RS01995
uniprot id: A0A1A9HYL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1176587:A8C56 RS07585
gene id: 1176587:A8C56_RS07585
uniprot id: A0A1A9I2C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1176587:A8C56 RS13860
gene id: 1176587:A8C56_RS13860
uniprot id: A0A1A9I5G9
names: Similarity
messages: Belongs to the IlvD/Edd family.

1176587:A8C56 RS07220
gene id: 1176587:A8C56_RS07220
uniprot id: A0A1A9HZH4
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS05530
gene id: 1176587:A8C56_RS05530
uniprot id: A0A1A9HZ32
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1176587:A8C56 RS13560
gene id: 1176587:A8C56_RS13560
uniprot id: A0A1A9I2V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1176587:A8C56 RS06590
gene id: 1176587:A8C56_RS06590
uniprot id: A0A1A9I1U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1176587:A8C56 RS11090
gene id: 1176587:A8C56_RS11090
uniprot id: A0A1A9I416
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS13275
gene id: 1176587:A8C56_RS13275
uniprot id: A0A1A9I8H6
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1176587:A8C56 RS10710
gene id: 1176587:A8C56_RS10710
uniprot id: A0A1A9I3X8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1176587:A8C56 RS03720
gene id: 1176587:A8C56_RS03720
uniprot id: A0A1A9HXU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1176587:A8C56 RS00665
gene id: 1176587:A8C56_RS00665
uniprot id: A0A1A9HZE0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1176587:A8C56 RS16965
gene id: 1176587:A8C56_RS16965
uniprot id: A0A1A9I6U8
names: Similarity
messages: Belongs to the DapB family.

1176587:A8C56 RS01970
gene id: 1176587:A8C56_RS01970
uniprot id: A0A1A9I027
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS04935
gene id: 1176587:A8C56_RS04935
uniprot id: A0A1A9HYB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1176587:A8C56 RS16020
gene id: 1176587:A8C56_RS16020
uniprot id: A0A1A9I6I2
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS05605
gene id: 1176587:A8C56_RS05605
uniprot id: A0A1A9HZN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1176587:A8C56 RS21825
gene id: 1176587:A8C56_RS21825
uniprot id: A0A1A9I7E8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1176587:A8C56 RS11895
gene id: 1176587:A8C56_RS11895
uniprot id: A0A1A9IA09
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS04925
gene id: 1176587:A8C56_RS04925
uniprot id: A0A1A9HYH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1176587:A8C56 RS22475
gene id: 1176587:A8C56_RS22475
uniprot id: A0A1A9I9M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1176587:A8C56 RS14920
gene id: 1176587:A8C56_RS14920
uniprot id: A0A1A9I607
names: Similarity
messages: Belongs to the AHA1 family.

1176587:A8C56 RS08780
gene id: 1176587:A8C56_RS08780
uniprot id: A0A1A9I2W3
names: Function
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.

1176587:A8C56 RS10345
gene id: 1176587:A8C56_RS10345
uniprot id: A0A1A9I3N3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1176587:A8C56 RS11235
gene id: 1176587:A8C56_RS11235
uniprot id: A0A1A9I1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

1176587:A8C56 RS21705
gene id: 1176587:A8C56_RS21705
uniprot id: A0A1A9I6P4
names: Similarity
messages: Belongs to the UPF0111 family.

1176587:A8C56 RS08285
gene id: 1176587:A8C56_RS08285
uniprot id: A0A1A9I882
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1176587:A8C56 RS18645
gene id: 1176587:A8C56_RS18645
uniprot id: A0A1A9I7T4
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS10525
gene id: 1176587:A8C56_RS10525
uniprot id: A0A1A9I3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS05010
gene id: 1176587:A8C56_RS05010
uniprot id: A0A1A9HYV2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1176587:A8C56 RS20670
gene id: 1176587:A8C56_RS20670
uniprot id: A0A1A9I977
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS14030
gene id: 1176587:A8C56_RS14030
uniprot id: A0A1A9I2Q0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1176587:A8C56 RS08660
gene id: 1176587:A8C56_RS08660
uniprot id: A0A1A9I894
names: Similarity
messages: Belongs to the ribF family.

1176587:A8C56 RS11115
gene id: 1176587:A8C56_RS11115
uniprot id: A0A1A9I2A1
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS14210
gene id: 1176587:A8C56_RS14210
uniprot id: A0A1A9I2S4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1176587:A8C56 RS14560
gene id: 1176587:A8C56_RS14560
uniprot id: A0A1A9I2Y2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1176587:A8C56 RS07655
gene id: 1176587:A8C56_RS07655
uniprot id: A0A1A9I1D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1176587:A8C56 RS00920
gene id: 1176587:A8C56_RS00920
uniprot id: A0A1A9HWE1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS00370
gene id: 1176587:A8C56_RS00370
uniprot id: A0A1A9HYR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS14245
gene id: 1176587:A8C56_RS14245
uniprot id: A0A1A9I366
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1176587:A8C56 RS09140
gene id: 1176587:A8C56_RS09140
uniprot id: A0A1A9I360
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1176587:A8C56 RS18100
gene id: 1176587:A8C56_RS18100
uniprot id: A0A1A9I8Y3
names: Similarity
messages: Belongs to the hyi family.

1176587:A8C56 RS01965
gene id: 1176587:A8C56_RS01965
uniprot id: A0A1A9HXE2
names: Similarity
messages: Belongs to the DinB family.

1176587:A8C56 RS17860
gene id: 1176587:A8C56_RS17860
uniprot id: A0A1A9I6B2
names: Similarity
messages: Belongs to the UxaA family.

1176587:A8C56 RS11025
gene id: 1176587:A8C56_RS11025
uniprot id: A0A1A9I304
names: Similarity
messages: Belongs to the universal stress protein A family.

1176587:A8C56 RS17580
gene id: 1176587:A8C56_RS17580
uniprot id: A0A1A9I7A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1176587:A8C56 RS04920
gene id: 1176587:A8C56_RS04920
uniprot id: A0A1A9HZA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1176587:A8C56 RS11105
gene id: 1176587:A8C56_RS11105
uniprot id: A0A1A9I1Q3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1176587:A8C56 RS15790
gene id: 1176587:A8C56_RS15790
uniprot id: A0A1A9I3I2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS20600
gene id: 1176587:A8C56_RS20600
uniprot id: A0A1A9I8R8
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS01740
gene id: 1176587:A8C56_RS01740
uniprot id: A0A1A9HWV8
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS03820
gene id: 1176587:A8C56_RS03820
uniprot id: A0A1A9I0Y8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1176587:A8C56 RS03475
gene id: 1176587:A8C56_RS03475
uniprot id: A0A1A9HXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1176587:A8C56 RS03980
gene id: 1176587:A8C56_RS03980
uniprot id: A0A1A9HYU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS12915
gene id: 1176587:A8C56_RS12915
uniprot id: A0A1A9I500
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS18785
gene id: 1176587:A8C56_RS18785
uniprot id: A0A1A9I4Z5
names: Similarity
messages: Belongs to the citrate synthase family.

1176587:A8C56 RS00085
gene id: 1176587:A8C56_RS00085
uniprot id: A0A1A9HWH4
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS11185
gene id: 1176587:A8C56_RS11185
uniprot id: A0A1A9I1D9
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS21640
gene id: 1176587:A8C56_RS21640
uniprot id: A0A1A9I984
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS10400
gene id: 1176587:A8C56_RS10400
uniprot id: A0A1A9I2Q2
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1176587:A8C56 RS19425
gene id: 1176587:A8C56_RS19425
uniprot id: A0A1A9I5G0
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS14325
gene id: 1176587:A8C56_RS14325
uniprot id: A0A1A9I2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS15670
gene id: 1176587:A8C56_RS15670
uniprot id: A0A1A9IB55
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1176587:A8C56 RS16655
gene id: 1176587:A8C56_RS16655
uniprot id: A0A1A9I4X7
names: Similarity
messages: Belongs to the peptidase C40 family.

1176587:A8C56 RS05585
gene id: 1176587:A8C56_RS05585
uniprot id: A0A1A9I9H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS11760
gene id: 1176587:A8C56_RS11760
uniprot id: A0A1A9I1L6
names: Similarity
messages: Belongs to the YciI family.

1176587:A8C56 RS06940
gene id: 1176587:A8C56_RS06940
uniprot id: A0A1A9HZB9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS10695
gene id: 1176587:A8C56_RS10695
uniprot id: A0A1A9I2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1176587:A8C56 RS00625
gene id: 1176587:A8C56_RS00625
uniprot id: A0A1A9HWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1176587:A8C56 RS04965
gene id: 1176587:A8C56_RS04965
uniprot id: A0A1A9I1I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1176587:A8C56 RS19950
gene id: 1176587:A8C56_RS19950
uniprot id: A0A1A9I6J8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1176587:A8C56 RS20720
gene id: 1176587:A8C56_RS20720
uniprot id: A0A1A9I8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS10575
gene id: 1176587:A8C56_RS10575
uniprot id: A0A1A9I2T4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1176587:A8C56 RS13715
gene id: 1176587:A8C56_RS13715
uniprot id: A0A1A9I4B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1176587:A8C56 RS06435
gene id: 1176587:A8C56_RS06435
uniprot id: A0A1A9I1U0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1176587:A8C56 RS19035
gene id: 1176587:A8C56_RS19035
uniprot id: A0A1A9I629
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1176587:A8C56 RS13065
gene id: 1176587:A8C56_RS13065
uniprot id: A0A1A9I299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

1176587:A8C56 RS05420
gene id: 1176587:A8C56_RS05420
uniprot id: A0A1A9HZ12
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS10465
gene id: 1176587:A8C56_RS10465
uniprot id: A0A1A9I8C7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1176587:A8C56 RS22030
gene id: 1176587:A8C56_RS22030
uniprot id: A0A1A9I9C0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1176587:A8C56 RS00145
gene id: 1176587:A8C56_RS00145
uniprot id: A0A1A9HZ46
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS23040
gene id: 1176587:A8C56_RS23040
uniprot id: A0A1A9I715
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1176587:A8C56 RS17495
gene id: 1176587:A8C56_RS17495
uniprot id: A0A1A9I4B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1176587:A8C56 RS18680
gene id: 1176587:A8C56_RS18680
uniprot id: A0A1A9I6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1176587:A8C56 RS01165
gene id: 1176587:A8C56_RS01165
uniprot id: A0A1A9HXF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1176587:A8C56 RS04940
gene id: 1176587:A8C56_RS04940
uniprot id: A0A1A9I018
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1176587:A8C56 RS10785
gene id: 1176587:A8C56_RS10785
uniprot id: A0A1A9IAZ6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1176587:A8C56 RS15255
gene id: 1176587:A8C56_RS15255
uniprot id: A0A1A9I4A3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1176587:A8C56 RS03080
gene id: 1176587:A8C56_RS03080
uniprot id: A0A1A9HXX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1176587:A8C56 RS01000
gene id: 1176587:A8C56_RS01000
uniprot id: A0A1A9HZ36
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1176587:A8C56 RS18370
gene id: 1176587:A8C56_RS18370
uniprot id: A0A1A9I4R6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS13640
gene id: 1176587:A8C56_RS13640
uniprot id: A0A1A9I2N0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1176587:A8C56 RS04270
gene id: 1176587:A8C56_RS04270
uniprot id: A0A1A9HY43
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1176587:A8C56 RS16820
gene id: 1176587:A8C56_RS16820
uniprot id: A0A1A9I402
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1176587:A8C56 RS03030
gene id: 1176587:A8C56_RS03030
uniprot id: A0A1A9I0L2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS08790
gene id: 1176587:A8C56_RS08790
uniprot id: A0A1A9I2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS16030
gene id: 1176587:A8C56_RS16030
uniprot id: A0A1A9I6U9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1176587:A8C56 RS14185
gene id: 1176587:A8C56_RS14185
uniprot id: A0A1A9I356
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS23510
gene id: 1176587:A8C56_RS23510
uniprot id: A0A1A9I7I1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1176587:A8C56 RS11950
gene id: 1176587:A8C56_RS11950
uniprot id: A0A1A9I4H8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1176587:A8C56 RS19135
gene id: 1176587:A8C56_RS19135
uniprot id: A0A1A9I5H6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1176587:A8C56 RS03715
gene id: 1176587:A8C56_RS03715
uniprot id: A0A1A9HXU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS19580
gene id: 1176587:A8C56_RS19580
uniprot id: A0A1A9I8P6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS02430
gene id: 1176587:A8C56_RS02430
uniprot id: A0A1A9HXL5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1176587:A8C56 RS16035
gene id: 1176587:A8C56_RS16035
uniprot id: A0A1A9I4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1176587:A8C56 RS19320
gene id: 1176587:A8C56_RS19320
uniprot id: A0A1A9I5D3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1176587:A8C56 RS03335
gene id: 1176587:A8C56_RS03335
uniprot id: A0A1A9HXN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1176587:A8C56 RS02180
gene id: 1176587:A8C56_RS02180
uniprot id: A0A1A9HZQ3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1176587:A8C56 RS09290
gene id: 1176587:A8C56_RS09290
uniprot id: A0A1A9I822
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS19660
gene id: 1176587:A8C56_RS19660
uniprot id: A0A1A9I6F1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1176587:A8C56 RS07695
gene id: 1176587:A8C56_RS07695
uniprot id: A0A1A9HZR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1176587:A8C56 RS23090
gene id: 1176587:A8C56_RS23090
uniprot id: A0A1A9I814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1176587:A8C56 RS00895
gene id: 1176587:A8C56_RS00895
uniprot id: A0A1A9HZH7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1176587:A8C56 RS03915
gene id: 1176587:A8C56_RS03915
uniprot id: A0A1A9I0M7
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1176587:A8C56 RS09845
gene id: 1176587:A8C56_RS09845
uniprot id: A0A1A9I0U5
names: Similarity
messages: Belongs to the IMPACT family.

1176587:A8C56 RS15090
gene id: 1176587:A8C56_RS15090
uniprot id: A0A1A9I373
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1176587:A8C56 RS19780
gene id: 1176587:A8C56_RS19780
uniprot id: A0A1A9I6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS22655
gene id: 1176587:A8C56_RS22655
uniprot id: A0A1A9I9A9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1176587:A8C56 RS23370
gene id: 1176587:A8C56_RS23370
uniprot id: A0A1A9I7G3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1176587:A8C56 RS08495
gene id: 1176587:A8C56_RS08495
uniprot id: A0A1A9I2R4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1176587:A8C56 RS06985
gene id: 1176587:A8C56_RS06985
uniprot id: A0A1A9HZC3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1176587:A8C56 RS16120
gene id: 1176587:A8C56_RS16120
uniprot id: A0A1A9I3N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1176587:A8C56 RS17750
gene id: 1176587:A8C56_RS17750
uniprot id: A0A1A9I7D9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1176587:A8C56 RS20280
gene id: 1176587:A8C56_RS20280
uniprot id: A0A1A9I5R1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1176587:A8C56 RS08365
gene id: 1176587:A8C56_RS08365
uniprot id: A0A1A9I1Q8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1176587:A8C56 RS15930
gene id: 1176587:A8C56_RS15930
uniprot id: A0A1A9I6D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1176587:A8C56 RS11840
gene id: 1176587:A8C56_RS11840
uniprot id: A0A1A9I4F4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1176587:A8C56 RS19460
gene id: 1176587:A8C56_RS19460
uniprot id: A0A1A9I860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1176587:A8C56 RS08060
gene id: 1176587:A8C56_RS08060
uniprot id: A0A1A9I0B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1176587:A8C56 RS21085
gene id: 1176587:A8C56_RS21085
uniprot id: A0A1A9I8X4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1176587:A8C56 RS19395
gene id: 1176587:A8C56_RS19395
uniprot id: A0A1A9I827
names: Similarity
messages: Belongs to the peptidase C1 family.

1176587:A8C56 RS14635
gene id: 1176587:A8C56_RS14635
uniprot id: A0A1A9I5S0
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS19385
gene id: 1176587:A8C56_RS19385
uniprot id: A0A1A9I5A7
names: Similarity
messages: Belongs to the peptidase C1 family.

1176587:A8C56 RS12725
gene id: 1176587:A8C56_RS12725
uniprot id: A0A1A9I279
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS19775
gene id: 1176587:A8C56_RS19775
uniprot id: A0A1A9I8S6
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS17665
gene id: 1176587:A8C56_RS17665
uniprot id: A0A1A9I4F5
names: Subcellular Location Annotation
messages: Secreted

1176587:A8C56 RS16495
gene id: 1176587:A8C56_RS16495
uniprot id: A0A1A9I3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1176587:A8C56 RS06180
gene id: 1176587:A8C56_RS06180
uniprot id: A0A1A9HZC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1176587:A8C56 RS07135
gene id: 1176587:A8C56_RS07135
uniprot id: A0A1A9HZT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS09035
gene id: 1176587:A8C56_RS09035
uniprot id: A0A1A9IAM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1176587:A8C56 RS16325
gene id: 1176587:A8C56_RS16325
uniprot id: A0A1A9I3R6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS17735
gene id: 1176587:A8C56_RS17735
uniprot id: A0A1A9IBG7
names: Similarity
messages: Belongs to the RecJ family.

1176587:A8C56 RS01225
gene id: 1176587:A8C56_RS01225
uniprot id: A0A1A9IAC9
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS04715
gene id: 1176587:A8C56_RS04715
uniprot id: A0A1A9HYC7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1176587:A8C56 RS03090
gene id: 1176587:A8C56_RS03090
uniprot id: A0A1A9HYE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1176587:A8C56 RS10565
gene id: 1176587:A8C56_RS10565
uniprot id: A0A1A9I127
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1176587:A8C56 RS22720
gene id: 1176587:A8C56_RS22720
uniprot id: A0A1A9I978
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS19510
gene id: 1176587:A8C56_RS19510
uniprot id: A0A1A9I875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS11815
gene id: 1176587:A8C56_RS11815
uniprot id: A0A1A9I1P0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1176587:A8C56 RS21725
gene id: 1176587:A8C56_RS21725
uniprot id: A0A1A9I6D0
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS03545
gene id: 1176587:A8C56_RS03545
uniprot id: A0A1A9IAH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1176587:A8C56 RS19225
gene id: 1176587:A8C56_RS19225
uniprot id: A0A1A9I919
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1176587:A8C56 RS22785
gene id: 1176587:A8C56_RS22785
uniprot id: A0A1A9I6X6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS00335
gene id: 1176587:A8C56_RS00335
uniprot id: A0A1A9HX15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1176587:A8C56 RS21800
gene id: 1176587:A8C56_RS21800
uniprot id: A0A1A9I980
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS01745
gene id: 1176587:A8C56_RS01745
uniprot id: A0A1A9HWT1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1176587:A8C56 RS04710
gene id: 1176587:A8C56_RS04710
uniprot id: A0A1A9HZ70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1176587:A8C56 RS12115
gene id: 1176587:A8C56_RS12115
uniprot id: A0A1A9I265
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1176587:A8C56 RS18520
gene id: 1176587:A8C56_RS18520
uniprot id: A0A1A9I847
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1176587:A8C56 RS00040
gene id: 1176587:A8C56_RS00040
uniprot id: A0A1A9HZ31
names: Similarity
messages: Belongs to the RutC family.

1176587:A8C56 RS01370
gene id: 1176587:A8C56_RS01370
uniprot id: A0A1A9HZA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1176587:A8C56 RS08095
gene id: 1176587:A8C56_RS08095
uniprot id: A0A1A9HZY1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS08775
gene id: 1176587:A8C56_RS08775
uniprot id: A0A1A9I1W7
names: Similarity
messages: Belongs to the pyruvate kinase family.

1176587:A8C56 RS03730
gene id: 1176587:A8C56_RS03730
uniprot id: A0A1A9I7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1176587:A8C56 RS18620
gene id: 1176587:A8C56_RS18620
uniprot id: A0A1A9I9M5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS11825
gene id: 1176587:A8C56_RS11825
uniprot id: A0A1A9I3D8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1176587:A8C56 RS11170
gene id: 1176587:A8C56_RS11170
uniprot id: A0A1A9I2B2
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS17820
gene id: 1176587:A8C56_RS17820
uniprot id: A0A1A9I7E9
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS17800
gene id: 1176587:A8C56_RS17800
uniprot id: A0A1A9I799
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS04140
gene id: 1176587:A8C56_RS04140
uniprot id: A0A1A9IAV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS10630
gene id: 1176587:A8C56_RS10630
uniprot id: A0A1A9I140
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1176587:A8C56 RS11920
gene id: 1176587:A8C56_RS11920
uniprot id: A0A1A9I1T3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS06195
gene id: 1176587:A8C56_RS06195
uniprot id: A0A1A9HZ19
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS09070
gene id: 1176587:A8C56_RS09070
uniprot id: A0A1A9I0D9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1176587:A8C56 RS20335
gene id: 1176587:A8C56_RS20335
uniprot id: A0A1A9I5Q1
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS13175
gene id: 1176587:A8C56_RS13175
uniprot id: A0A1A9IBH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1176587:A8C56 RS00825
gene id: 1176587:A8C56_RS00825
uniprot id: A0A1A9HZ09
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1176587:A8C56 RS04690
gene id: 1176587:A8C56_RS04690
uniprot id: A0A1A9I0X9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1176587:A8C56 RS17445
gene id: 1176587:A8C56_RS17445
uniprot id: A0A1A9I4B2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1176587:A8C56 RS14450
gene id: 1176587:A8C56_RS14450
uniprot id: A0A1A9I4N4
names: Similarity
messages: Belongs to the UPF0502 family.

1176587:A8C56 RS11555
gene id: 1176587:A8C56_RS11555
uniprot id: A0A1A9I1M1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1176587:A8C56 RS16365
gene id: 1176587:A8C56_RS16365
uniprot id: A0A1A9I449
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1176587:A8C56 RS17615
gene id: 1176587:A8C56_RS17615
uniprot id: A0A1A9I4E5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1176587:A8C56 RS09345
gene id: 1176587:A8C56_RS09345
uniprot id: A0A1A9I1E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1176587:A8C56 RS04265
gene id: 1176587:A8C56_RS04265
uniprot id: A0A1A9I7P1
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS14950
gene id: 1176587:A8C56_RS14950
uniprot id: A0A1A9I399
names: Similarity
messages: Belongs to the AHA1 family.

1176587:A8C56 RS03415
gene id: 1176587:A8C56_RS03415
uniprot id: A0A1A9I0A4
names: Similarity
messages: Belongs to the FPG family.

1176587:A8C56 RS15840
gene id: 1176587:A8C56_RS15840
uniprot id: A0A1A9I3N6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS11595
gene id: 1176587:A8C56_RS11595
uniprot id: A0A1A9I4B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1176587:A8C56 RS00065
gene id: 1176587:A8C56_RS00065
uniprot id: A0A1A9HXN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1176587:A8C56 RS01830
gene id: 1176587:A8C56_RS01830
uniprot id: A0A1A9HXB7
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1176587:A8C56 RS08985
gene id: 1176587:A8C56_RS08985
uniprot id: A0A1A9I185
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1176587:A8C56 RS15095
gene id: 1176587:A8C56_RS15095
uniprot id: A0A1A9I4Z0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1176587:A8C56 RS21125
gene id: 1176587:A8C56_RS21125
uniprot id: A0A1A9I623
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS02190
gene id: 1176587:A8C56_RS02190
uniprot id: A0A1A9HXI1
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

1176587:A8C56 RS20475
gene id: 1176587:A8C56_RS20475
uniprot id: A0A1A9I8N6
names: Similarity
messages: Belongs to the DapA family.

1176587:A8C56 RS07315
gene id: 1176587:A8C56_RS07315
uniprot id: A0A1A9I297
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1176587:A8C56 RS20040
gene id: 1176587:A8C56_RS20040
uniprot id: A0A1A9IBH1
names: Similarity
messages: Belongs to the DinB family.

1176587:A8C56 RS21910
gene id: 1176587:A8C56_RS21910
uniprot id: A0A1A9I988
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1176587:A8C56 RS05575
gene id: 1176587:A8C56_RS05575
uniprot id: A0A1A9I1F3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1176587:A8C56 RS19170
gene id: 1176587:A8C56_RS19170
uniprot id: A0A1A9I6Z5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1176587:A8C56 RS08735
gene id: 1176587:A8C56_RS08735
uniprot id: A0A1A9I0L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1176587:A8C56 RS16200
gene id: 1176587:A8C56_RS16200
uniprot id: A0A1A9I420
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1176587:A8C56 RS06990
gene id: 1176587:A8C56_RS06990
uniprot id: A0A1A9HZD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1176587:A8C56 RS22395
gene id: 1176587:A8C56_RS22395
uniprot id: A0A1A9I6P7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1176587:A8C56 RS19240
gene id: 1176587:A8C56_RS19240
uniprot id: A0A1A9I824
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS11180
gene id: 1176587:A8C56_RS11180
uniprot id: A0A1A9I1C6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS09625
gene id: 1176587:A8C56_RS09625
uniprot id: A0A1A9I0Q7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS09790
gene id: 1176587:A8C56_RS09790
uniprot id: A0A1A9I0T6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1176587:A8C56 RS11290
gene id: 1176587:A8C56_RS11290
uniprot id: A0A1A9IAT2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1176587:A8C56 RS05675
gene id: 1176587:A8C56_RS05675
uniprot id: A0A1A9HYT4
names: Similarity
messages: Belongs to the aspartokinase family.

1176587:A8C56 RS13160
gene id: 1176587:A8C56_RS13160
uniprot id: A0A1A9I540
names: Similarity
messages: Belongs to the DtxR/MntR family.

1176587:A8C56 RS15375
gene id: 1176587:A8C56_RS15375
uniprot id: A0A1A9I4C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS11615
gene id: 1176587:A8C56_RS11615
uniprot id: A0A1A9I2H5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1176587:A8C56 RS13530
gene id: 1176587:A8C56_RS13530
uniprot id: A0A1A9I592
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS01890
gene id: 1176587:A8C56_RS01890
uniprot id: A0A1A9I016
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS08980
gene id: 1176587:A8C56_RS08980
uniprot id: A0A1A9I3F0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1176587:A8C56 RS13165
gene id: 1176587:A8C56_RS13165
uniprot id: A0A1A9I2P6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS16355
gene id: 1176587:A8C56_RS16355
uniprot id: A0A1A9I6J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS22745
gene id: 1176587:A8C56_RS22745
uniprot id: A0A1A9I9S1
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1176587:A8C56 RS18815
gene id: 1176587:A8C56_RS18815
uniprot id: A0A1A9I888
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS10880
gene id: 1176587:A8C56_RS10880
uniprot id: A0A1A9I2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1176587:A8C56 RS07540
gene id: 1176587:A8C56_RS07540
uniprot id: A0A1A9I2E0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1176587:A8C56 RS23205
gene id: 1176587:A8C56_RS23205
uniprot id: A0A1A9I7A3
names: Subunit
messages: Homodimer.

1176587:A8C56 RS15885
gene id: 1176587:A8C56_RS15885
uniprot id: A0A1A9I3X6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1176587:A8C56 RS06905
gene id: 1176587:A8C56_RS06905
uniprot id: A0A1A9I220
names: Similarity
messages: Belongs to the aldose epimerase family.

1176587:A8C56 RS00715
gene id: 1176587:A8C56_RS00715
uniprot id: A0A1A9HWT0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1176587:A8C56 RS10505
gene id: 1176587:A8C56_RS10505
uniprot id: A0A1A9I117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS17950
gene id: 1176587:A8C56_RS17950
uniprot id: A0A1A9I5J7
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1176587:A8C56 RS13105
gene id: 1176587:A8C56_RS13105
uniprot id: A0A1A9I2N7
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS10200
gene id: 1176587:A8C56_RS10200
uniprot id: A0A1A9I1A7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS03615
gene id: 1176587:A8C56_RS03615
uniprot id: A0A1A9HXN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1176587:A8C56 RS11165
gene id: 1176587:A8C56_RS11165
uniprot id: A0A1A9I4G9
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS10545
gene id: 1176587:A8C56_RS10545
uniprot id: A0A1A9I8A3
names: Similarity
messages: Belongs to the thioredoxin family.

1176587:A8C56 RS10990
gene id: 1176587:A8C56_RS10990
uniprot id: A0A1A9I4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1176587:A8C56 RS01690
gene id: 1176587:A8C56_RS01690
uniprot id: A0A1A9HWU8
names: Similarity
messages: Belongs to the group II decarboxylase family.

1176587:A8C56 RS00450
gene id: 1176587:A8C56_RS00450
uniprot id: A0A1A9HX32
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1176587:A8C56 RS06540
gene id: 1176587:A8C56_RS06540
uniprot id: A0A1A9I1U6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS03460
gene id: 1176587:A8C56_RS03460
uniprot id: A0A1A9HXQ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1176587:A8C56 RS02860
gene id: 1176587:A8C56_RS02860
uniprot id: A0A1A9I0I3
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS22810
gene id: 1176587:A8C56_RS22810
uniprot id: A0A1A9I9T1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1176587:A8C56 RS20220
gene id: 1176587:A8C56_RS20220
uniprot id: A0A1A9I5Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1176587:A8C56 RS19080
gene id: 1176587:A8C56_RS19080
uniprot id: A0A1A9I5G6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1176587:A8C56 RS02420
gene id: 1176587:A8C56_RS02420
uniprot id: A0A1A9HZT8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1176587:A8C56 RS06950
gene id: 1176587:A8C56_RS06950
uniprot id: A0A1A9I213
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1176587:A8C56 RS22080
gene id: 1176587:A8C56_RS22080
uniprot id: A0A1A9I9B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1176587:A8C56 RS21770
gene id: 1176587:A8C56_RS21770
uniprot id: A0A1A9I6L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS10390
gene id: 1176587:A8C56_RS10390
uniprot id: A0A1A9IAY6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1176587:A8C56 RS05975
gene id: 1176587:A8C56_RS05975
uniprot id: A0A1A9I1M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1176587:A8C56 RS04955
gene id: 1176587:A8C56_RS04955
uniprot id: A0A1A9I153
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1176587:A8C56 RS06155
gene id: 1176587:A8C56_RS06155
uniprot id: A0A1A9I1M3
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS10140
gene id: 1176587:A8C56_RS10140
uniprot id: A0A1A9I195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1176587:A8C56 RS07705
gene id: 1176587:A8C56_RS07705
uniprot id: A0A1A9HZP6
names: Similarity
messages: Belongs to the peptidase C1 family.

1176587:A8C56 RS12070
gene id: 1176587:A8C56_RS12070
uniprot id: A0A1A9I4Y3
names: Similarity
messages: Belongs to the XFP family.

1176587:A8C56 RS10980
gene id: 1176587:A8C56_RS10980
uniprot id: A0A1A9I1N0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1176587:A8C56 RS12650
gene id: 1176587:A8C56_RS12650
uniprot id: A0A1A9I267
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1176587:A8C56 RS18670
gene id: 1176587:A8C56_RS18670
uniprot id: A0A1A9I4W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS06675
gene id: 1176587:A8C56_RS06675
uniprot id: A0A1A9I1Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1176587:A8C56 RS02765
gene id: 1176587:A8C56_RS02765
uniprot id: A0A1A9HY84
names: Similarity
messages: Belongs to the bacterial secretin family.

1176587:A8C56 RS04485
gene id: 1176587:A8C56_RS04485
uniprot id: A0A1A9I196
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS08540
gene id: 1176587:A8C56_RS08540
uniprot id: A0A1A9I049
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS10280
gene id: 1176587:A8C56_RS10280
uniprot id: A0A1A9I0X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS19880
gene id: 1176587:A8C56_RS19880
uniprot id: A0A1A9I8U5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1176587:A8C56 RS07635
gene id: 1176587:A8C56_RS07635
uniprot id: A0A1A9HZM6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS15875
gene id: 1176587:A8C56_RS15875
uniprot id: A0A1A9I6G2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1176587:A8C56 RS10270
gene id: 1176587:A8C56_RS10270
uniprot id: A0A1A9I1V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1176587:A8C56 RS20120
gene id: 1176587:A8C56_RS20120
uniprot id: A0A1A9I8I0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1176587:A8C56 RS09160
gene id: 1176587:A8C56_RS09160
uniprot id: A0A1A9IAR1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1176587:A8C56 RS05480
gene id: 1176587:A8C56_RS05480
uniprot id: A0A1A9HZK3
names: Similarity
messages: Belongs to the MoaD family.

1176587:A8C56 RS12085
gene id: 1176587:A8C56_RS12085
uniprot id: A0A1A9I1S7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1176587:A8C56 RS00190
gene id: 1176587:A8C56_RS00190
uniprot id: A0A1A9HXQ1
names: Similarity
messages: Belongs to the SCO1/2 family.

1176587:A8C56 RS19000
gene id: 1176587:A8C56_RS19000
uniprot id: A0A1A9I532
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS07225
gene id: 1176587:A8C56_RS07225
uniprot id: A0A1A9I159
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1176587:A8C56 RS05710
gene id: 1176587:A8C56_RS05710
uniprot id: A0A1A9HZ61
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1176587:A8C56 RS09320
gene id: 1176587:A8C56_RS09320
uniprot id: A0A1A9I357
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1176587:A8C56 RS02650
gene id: 1176587:A8C56_RS02650
uniprot id: A0A1A9IAF5
names: Subcellular Location Annotation
messages: Mitochondrion

1176587:A8C56 RS06330
gene id: 1176587:A8C56_RS06330
uniprot id: A0A1A9HZ15
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1176587:A8C56 RS23715
gene id: 1176587:A8C56_RS23715
uniprot id: A0A1A9I937
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS08635
gene id: 1176587:A8C56_RS08635
uniprot id: A0A1A9I088
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS02025
gene id: 1176587:A8C56_RS02025
uniprot id: A0A1A9HXX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1176587:A8C56 RS21520
gene id: 1176587:A8C56_RS21520
uniprot id: A0A1A9I825
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1176587:A8C56 RS16110
gene id: 1176587:A8C56_RS16110
uniprot id: A0A1A9I4N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1176587:A8C56 RS21070
gene id: 1176587:A8C56_RS21070
uniprot id: A0A1A9I642
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1176587:A8C56 RS23640
gene id: 1176587:A8C56_RS23640
uniprot id: A0A1A9IAH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1176587:A8C56 RS10455
gene id: 1176587:A8C56_RS10455
uniprot id: A0A1A9I2R2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1176587:A8C56 RS14550
gene id: 1176587:A8C56_RS14550
uniprot id: A0A1A9I331
names: Similarity
messages: Belongs to the MQO family.

1176587:A8C56 RS01695
gene id: 1176587:A8C56_RS01695
uniprot id: A0A1A9HWS1
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS08460
gene id: 1176587:A8C56_RS08460
uniprot id: A0A1A9I358
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS05385
gene id: 1176587:A8C56_RS05385
uniprot id: A0A1A9HYK0
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS09105
gene id: 1176587:A8C56_RS09105
uniprot id: A0A1A9I1A6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1176587:A8C56 RS12175
gene id: 1176587:A8C56_RS12175
uniprot id: A0A1A9I2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS19315
gene id: 1176587:A8C56_RS19315
uniprot id: A0A1A9I678
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1176587:A8C56 RS09925
gene id: 1176587:A8C56_RS09925
uniprot id: A0A1A9IAP5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1176587:A8C56 RS15330
gene id: 1176587:A8C56_RS15330
uniprot id: A0A1A9I3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1176587:A8C56 RS08195
gene id: 1176587:A8C56_RS08195
uniprot id: A0A1A9I318
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1176587:A8C56 RS00170
gene id: 1176587:A8C56_RS00170
uniprot id: A0A1A9HW38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1176587:A8C56 RS00300
gene id: 1176587:A8C56_RS00300
uniprot id: A0A1A9IA52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS23765
gene id: 1176587:A8C56_RS23765
uniprot id: A0A1A9I947
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1176587:A8C56 RS14010
gene id: 1176587:A8C56_RS14010
uniprot id: A0A1A9I3P3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1176587:A8C56 RS01850
gene id: 1176587:A8C56_RS01850
uniprot id: A0A1A9HWX7
names: Similarity
messages: Belongs to the SUI1 family.

1176587:A8C56 RS18095
gene id: 1176587:A8C56_RS18095
uniprot id: A0A1A9I6E7
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS05430
gene id: 1176587:A8C56_RS05430
uniprot id: A0A1A9HZJ4
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS17530
gene id: 1176587:A8C56_RS17530
uniprot id: A0A1A9I8N1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1176587:A8C56 RS05425
gene id: 1176587:A8C56_RS05425
uniprot id: A0A1A9I1R4
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1176587:A8C56 RS22100
gene id: 1176587:A8C56_RS22100
uniprot id: A0A1A9I9U9
names: Similarity
messages: Belongs to the CarB family.

1176587:A8C56 RS22510
gene id: 1176587:A8C56_RS22510
uniprot id: A0A1A9IA11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1176587:A8C56 RS21250
gene id: 1176587:A8C56_RS21250
uniprot id: A0A1A9I7Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1176587:A8C56 RS21245
gene id: 1176587:A8C56_RS21245
uniprot id: A0A1A9I671
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1176587:A8C56 RS23195
gene id: 1176587:A8C56_RS23195
uniprot id: A0A1A9IAA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS22270
gene id: 1176587:A8C56_RS22270
uniprot id: A0A1A9I6Z3
names: Similarity
messages: Belongs to the ArsC family.

1176587:A8C56 RS04670
gene id: 1176587:A8C56_RS04670
uniprot id: A0A1A9HYA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1176587:A8C56 RS04980
gene id: 1176587:A8C56_RS04980
uniprot id: A0A1A9HYG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1176587:A8C56 RS07310
gene id: 1176587:A8C56_RS07310
uniprot id: A0A1A9I284
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1176587:A8C56 RS07265
gene id: 1176587:A8C56_RS07265
uniprot id: A0A1A9I2J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1176587:A8C56 RS23125
gene id: 1176587:A8C56_RS23125
uniprot id: A0A1A9I9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS02600
gene id: 1176587:A8C56_RS02600
uniprot id: A0A1A9HY61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1176587:A8C56 RS23135
gene id: 1176587:A8C56_RS23135
uniprot id: A0A1A9I7C6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS20065
gene id: 1176587:A8C56_RS20065
uniprot id: A0A1A9I8H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1176587:A8C56 RS03050
gene id: 1176587:A8C56_RS03050
uniprot id: A0A1A9HXI8
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS18570
gene id: 1176587:A8C56_RS18570
uniprot id: A0A1A9I8Z9
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS18190
gene id: 1176587:A8C56_RS18190
uniprot id: A0A1A9I7Y6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1176587:A8C56 RS09455
gene id: 1176587:A8C56_RS09455
uniprot id: A0A1A9I1G5
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS13145
gene id: 1176587:A8C56_RS13145
uniprot id: A0A1A9I8K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1176587:A8C56 RS09270
gene id: 1176587:A8C56_RS09270
uniprot id: A0A1A9I379
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1176587:A8C56 RS00285
gene id: 1176587:A8C56_RS00285
uniprot id: A0A1A9HW58
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS16500
gene id: 1176587:A8C56_RS16500
uniprot id: A0A1A9I5L3
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS04055
gene id: 1176587:A8C56_RS04055
uniprot id: A0A1A9HXW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1176587:A8C56 RS10435
gene id: 1176587:A8C56_RS10435
uniprot id: A0A1A9I1Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1176587:A8C56 RS18115
gene id: 1176587:A8C56_RS18115
uniprot id: A0A1A9I7K0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1176587:A8C56 RS15675
gene id: 1176587:A8C56_RS15675
uniprot id: A0A1A9I585
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1176587:A8C56 RS02050
gene id: 1176587:A8C56_RS02050
uniprot id: A0A1A9HWY7
names: Similarity
messages: Belongs to the DinB family.

1176587:A8C56 RS16085
gene id: 1176587:A8C56_RS16085
uniprot id: A0A1A9I6D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1176587:A8C56 RS01645
gene id: 1176587:A8C56_RS01645
uniprot id: A0A1A9HWR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1176587:A8C56 RS18355
gene id: 1176587:A8C56_RS18355
uniprot id: A0A1A9I820
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1176587:A8C56 RS16550
gene id: 1176587:A8C56_RS16550
uniprot id: A0A1A9I406
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1176587:A8C56 RS18965
gene id: 1176587:A8C56_RS18965
uniprot id: A0A1A9I7W3
names: Similarity
messages: Belongs to the pirin family.

1176587:A8C56 RS19630
gene id: 1176587:A8C56_RS19630
uniprot id: A0A1A9I878
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1176587:A8C56 RS18790
gene id: 1176587:A8C56_RS18790
uniprot id: A0A1A9I6S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1176587:A8C56 RS06945
gene id: 1176587:A8C56_RS06945
uniprot id: A0A1A9I103
names: Similarity
messages: Belongs to the UPF0234 family.

1176587:A8C56 RS05265
gene id: 1176587:A8C56_RS05265
uniprot id: A0A1A9HYH5
names: Similarity
messages: Belongs to the DtxR/MntR family.

1176587:A8C56 RS00995
gene id: 1176587:A8C56_RS00995
uniprot id: A0A1A9HY39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1176587:A8C56 RS02330
gene id: 1176587:A8C56_RS02330
uniprot id: A0A1A9HX52
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1176587:A8C56 RS09855
gene id: 1176587:A8C56_RS09855
uniprot id: A0A1A9I0S2
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1176587:A8C56 RS03425
gene id: 1176587:A8C56_RS03425
uniprot id: A0A1A9HY33
names: Similarity
messages: Belongs to the peptidase C56 family.

1176587:A8C56 RS02135
gene id: 1176587:A8C56_RS02135
uniprot id: A0A1A9HXZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1176587:A8C56 RS03205
gene id: 1176587:A8C56_RS03205
uniprot id: A0A1A9I0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1176587:A8C56 RS03675
gene id: 1176587:A8C56_RS03675
uniprot id: A0A1A9HZG3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1176587:A8C56 RS16520
gene id: 1176587:A8C56_RS16520
uniprot id: A0A1A9I6R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1176587:A8C56 RS10930
gene id: 1176587:A8C56_RS10930
uniprot id: A0A1A9I1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS12730
gene id: 1176587:A8C56_RS12730
uniprot id: A0A1A9I234
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1176587:A8C56 RS00910
gene id: 1176587:A8C56_RS00910
uniprot id: A0A1A9HWG0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1176587:A8C56 RS10640
gene id: 1176587:A8C56_RS10640
uniprot id: A0A1A9I146
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS02565
gene id: 1176587:A8C56_RS02565
uniprot id: A0A1A9HX70
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS07305
gene id: 1176587:A8C56_RS07305
uniprot id: A0A1A9I272
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1176587:A8C56 RS09825
gene id: 1176587:A8C56_RS09825
uniprot id: A0A1A9I149
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1176587:A8C56 RS05205
gene id: 1176587:A8C56_RS05205
uniprot id: A0A1A9HYG5
names: Similarity
messages: Belongs to the peptidase S41A family.

1176587:A8C56 RS15180
gene id: 1176587:A8C56_RS15180
uniprot id: A0A1A9I3M1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1176587:A8C56 RS04900
gene id: 1176587:A8C56_RS04900
uniprot id: A0A1A9I120
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1176587:A8C56 RS15705
gene id: 1176587:A8C56_RS15705
uniprot id: A0A1A9I6P8
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1176587:A8C56 RS08450
gene id: 1176587:A8C56_RS08450
uniprot id: A0A1A9I2U7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1176587:A8C56 RS04990
gene id: 1176587:A8C56_RS04990
uniprot id: A0A1A9I029
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1176587:A8C56 RS11935
gene id: 1176587:A8C56_RS11935
uniprot id: A0A1A9I3F6
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS07960
gene id: 1176587:A8C56_RS07960
uniprot id: A0A1A9I0A1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1176587:A8C56 RS14725
gene id: 1176587:A8C56_RS14725
uniprot id: A0A1A9I309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1176587:A8C56 RS12740
gene id: 1176587:A8C56_RS12740
uniprot id: A0A1A9I245
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS16290
gene id: 1176587:A8C56_RS16290
uniprot id: A0A1A9I6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1176587:A8C56 RS18590
gene id: 1176587:A8C56_RS18590
uniprot id: A0A1A9I5U7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS09775
gene id: 1176587:A8C56_RS09775
uniprot id: A0A1A9I137
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS03190
gene id: 1176587:A8C56_RS03190
uniprot id: A0A1A9I066
names: Similarity
messages: Belongs to the LOG family.

1176587:A8C56 RS04000
gene id: 1176587:A8C56_RS04000
uniprot id: A0A1A9HZL4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS04595
gene id: 1176587:A8C56_RS04595
uniprot id: A0A1A9HYM5
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS12220
gene id: 1176587:A8C56_RS12220
uniprot id: A0A1A9I285
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1176587:A8C56 RS15990
gene id: 1176587:A8C56_RS15990
uniprot id: A0A1A9I6C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS19505
gene id: 1176587:A8C56_RS19505
uniprot id: A0A1A9I855
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS17435
gene id: 1176587:A8C56_RS17435
uniprot id: A0A1A9I4G5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS19350
gene id: 1176587:A8C56_RS19350
uniprot id: A0A1A9I863
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS04545
gene id: 1176587:A8C56_RS04545
uniprot id: A0A1A9HZ37
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS19175
gene id: 1176587:A8C56_RS19175
uniprot id: A0A1A9I7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1176587:A8C56 RS01605
gene id: 1176587:A8C56_RS01605
uniprot id: A0A1A9HZE8
names: Similarity
messages: Belongs to the TrpF family.

1176587:A8C56 RS03670
gene id: 1176587:A8C56_RS03670
uniprot id: A0A1A9HXP8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1176587:A8C56 RS13020
gene id: 1176587:A8C56_RS13020
uniprot id: A0A1A9I536
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1176587:A8C56 RS19520
gene id: 1176587:A8C56_RS19520
uniprot id: A0A1A9I8R3
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS06695
gene id: 1176587:A8C56_RS06695
uniprot id: A0A1A9IB10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1176587:A8C56 RS12610
gene id: 1176587:A8C56_RS12610
uniprot id: A0A1A9I4V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1176587:A8C56 RS03115
gene id: 1176587:A8C56_RS03115
uniprot id: A0A1A9HZ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1176587:A8C56 RS01570
gene id: 1176587:A8C56_RS01570
uniprot id: A0A1A9HWS4
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS04985
gene id: 1176587:A8C56_RS04985
uniprot id: A0A1A9HYD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1176587:A8C56 RS03290
gene id: 1176587:A8C56_RS03290
uniprot id: A0A1A9HXN2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1176587:A8C56 RS12690
gene id: 1176587:A8C56_RS12690
uniprot id: A0A1A9IB05
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS23360
gene id: 1176587:A8C56_RS23360
uniprot id: A0A1A9IA20
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1176587:A8C56 RS19560
gene id: 1176587:A8C56_RS19560
uniprot id: A0A1A9I868
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1176587:A8C56 RS18625
gene id: 1176587:A8C56_RS18625
uniprot id: A0A1A9I6P2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiD family. UbiD-like/FDC subfamily.
messages: Binds 1 K(+) per subunit.
messages: Binds 1 Mn(2+) per subunit.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the prenyl-FMN-dependent decarboxylation of pyrrole-2-carboxylate (P2C). Can also catalyze the carboxylation of pyrrole in the presence of elevated concentrations of CO(2) or bicarbonate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS17420
gene id: 1176587:A8C56_RS17420
uniprot id: A0A1A9I4N3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1176587:A8C56 RS00735
gene id: 1176587:A8C56_RS00735
uniprot id: A0A1A9HWD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1176587:A8C56 RS05665
gene id: 1176587:A8C56_RS05665
uniprot id: A0A1A9HZP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1176587:A8C56 RS20770
gene id: 1176587:A8C56_RS20770
uniprot id: A0A1A9I5W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1176587:A8C56 RS16865
gene id: 1176587:A8C56_RS16865
uniprot id: A0A1A9IBS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1176587:A8C56 RS10960
gene id: 1176587:A8C56_RS10960
uniprot id: A0A1A9I3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS02520
gene id: 1176587:A8C56_RS02520
uniprot id: A0A1A9HYX6
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS16175
gene id: 1176587:A8C56_RS16175
uniprot id: A0A1A9I3P6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1176587:A8C56 RS02315
gene id: 1176587:A8C56_RS02315
uniprot id: A0A1A9I091
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS11280
gene id: 1176587:A8C56_RS11280
uniprot id: A0A1A9I4K1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1176587:A8C56 RS15900
gene id: 1176587:A8C56_RS15900
uniprot id: A0A1A9I3P5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1176587:A8C56 RS15250
gene id: 1176587:A8C56_RS15250
uniprot id: A0A1A9I6I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1176587:A8C56 RS08395
gene id: 1176587:A8C56_RS08395
uniprot id: A0A1A9I349
names: Similarity
messages: Belongs to the RelE toxin family.

1176587:A8C56 RS01875
gene id: 1176587:A8C56_RS01875
uniprot id: A0A1A9HZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1176587:A8C56 RS09220
gene id: 1176587:A8C56_RS09220
uniprot id: A0A1A9I371
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1176587:A8C56 RS19265
gene id: 1176587:A8C56_RS19265
uniprot id: A0A1A9I666
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS18225
gene id: 1176587:A8C56_RS18225
uniprot id: A0A1A9I7H3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS16405
gene id: 1176587:A8C56_RS16405
uniprot id: A0A1A9I6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS16280
gene id: 1176587:A8C56_RS16280
uniprot id: A0A1A9I3R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS16995
gene id: 1176587:A8C56_RS16995
uniprot id: A0A1A9I483
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1176587:A8C56 RS09330
gene id: 1176587:A8C56_RS09330
uniprot id: A0A1A9I393
names: Similarity
messages: Belongs to the NusB family.

1176587:A8C56 RS21745
gene id: 1176587:A8C56_RS21745
uniprot id: A0A1A9I9A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1176587:A8C56 RS01110
gene id: 1176587:A8C56_RS01110
uniprot id: A0A1A9HXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS01475
gene id: 1176587:A8C56_RS01475
uniprot id: A0A1A9HYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1176587:A8C56 RS01865
gene id: 1176587:A8C56_RS01865
uniprot id: A0A1A9HYJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1176587:A8C56 RS14020
gene id: 1176587:A8C56_RS14020
uniprot id: A0A1A9I2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1176587:A8C56 RS07280
gene id: 1176587:A8C56_RS07280
uniprot id: A0A1A9I0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1176587:A8C56 RS07590
gene id: 1176587:A8C56_RS07590
uniprot id: A0A1A9I2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1176587:A8C56 RS03680
gene id: 1176587:A8C56_RS03680
uniprot id: A0A1A9I0E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1176587:A8C56 RS11050
gene id: 1176587:A8C56_RS11050
uniprot id: A0A1A9I4E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1176587:A8C56 RS10395
gene id: 1176587:A8C56_RS10395
uniprot id: A0A1A9I113
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1176587:A8C56 RS03610
gene id: 1176587:A8C56_RS03610
uniprot id: A0A1A9HXS7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1176587:A8C56 RS06895
gene id: 1176587:A8C56_RS06895
uniprot id: A0A1A9I203
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1176587:A8C56 RS20245
gene id: 1176587:A8C56_RS20245
uniprot id: A0A1A9I8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1176587:A8C56 RS18595
gene id: 1176587:A8C56_RS18595
uniprot id: A0A1A9IBV8
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS09870
gene id: 1176587:A8C56_RS09870
uniprot id: A0A1A9I3J1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1176587:A8C56 RS04745
gene id: 1176587:A8C56_RS04745
uniprot id: A0A1A9I0Y4
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1176587:A8C56 RS12100
gene id: 1176587:A8C56_RS12100
uniprot id: A0A1A9I4I9
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS15530
gene id: 1176587:A8C56_RS15530
uniprot id: A0A1A9I3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS18505
gene id: 1176587:A8C56_RS18505
uniprot id: A0A1A9I7M7
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS16880
gene id: 1176587:A8C56_RS16880
uniprot id: A0A1A9I413
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1176587:A8C56 RS01595
gene id: 1176587:A8C56_RS01595
uniprot id: A0A1A9HYE2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS23110
gene id: 1176587:A8C56_RS23110
uniprot id: A0A1A9I727
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1176587:A8C56 RS08745
gene id: 1176587:A8C56_RS08745
uniprot id: A0A1A9I144
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS18840
gene id: 1176587:A8C56_RS18840
uniprot id: A0A1A9I6T4
names: Similarity
messages: Belongs to the YciI family.

1176587:A8C56 RS04650
gene id: 1176587:A8C56_RS04650
uniprot id: A0A1A9HYN2
names: Similarity
messages: Belongs to the universal stress protein A family.

1176587:A8C56 RS12440
gene id: 1176587:A8C56_RS12440
uniprot id: A0A1A9I2C6
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS21095
gene id: 1176587:A8C56_RS21095
uniprot id: A0A1A9I6E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1176587:A8C56 RS04735
gene id: 1176587:A8C56_RS04735
uniprot id: A0A1A9HY78
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1176587:A8C56 RS11125
gene id: 1176587:A8C56_RS11125
uniprot id: A0A1A9I1B7
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS01555
gene id: 1176587:A8C56_RS01555
uniprot id: A0A1A9HZU0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS22380
gene id: 1176587:A8C56_RS22380
uniprot id: A0A1A9I9Z6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS14255
gene id: 1176587:A8C56_RS14255
uniprot id: A0A1A9I3T2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1176587:A8C56 RS03540
gene id: 1176587:A8C56_RS03540
uniprot id: A0A1A9HXR8
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS19725
gene id: 1176587:A8C56_RS19725
uniprot id: A0A1A9I8R6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS15210
gene id: 1176587:A8C56_RS15210
uniprot id: A0A1A9I389
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1176587:A8C56 RS08560
gene id: 1176587:A8C56_RS08560
uniprot id: A0A1A9I2W6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1176587:A8C56 RS20100
gene id: 1176587:A8C56_RS20100
uniprot id: A0A1A9I5N2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1176587:A8C56 RS18640
gene id: 1176587:A8C56_RS18640
uniprot id: A0A1A9I7P7
names: Similarity
messages: Belongs to the peptidase S51 family.

1176587:A8C56 RS05475
gene id: 1176587:A8C56_RS05475
uniprot id: A0A1A9I1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS12005
gene id: 1176587:A8C56_RS12005
uniprot id: A0A1A9I4I7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1176587:A8C56 RS22750
gene id: 1176587:A8C56_RS22750
uniprot id: A0A1A9I9N1
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1176587:A8C56 RS10690
gene id: 1176587:A8C56_RS10690
uniprot id: A0A1A9I155
names: Similarity
messages: Belongs to the threonine aldolase family.

1176587:A8C56 RS19165
gene id: 1176587:A8C56_RS19165
uniprot id: A0A1A9I564
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1176587:A8C56 RS16295
gene id: 1176587:A8C56_RS16295
uniprot id: A0A1A9I6I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS07910
gene id: 1176587:A8C56_RS07910
uniprot id: A0A1A9IAN2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1176587:A8C56 RS13290
gene id: 1176587:A8C56_RS13290
uniprot id: A0A1A9I2R5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1176587:A8C56 RS13135
gene id: 1176587:A8C56_RS13135
uniprot id: A0A1A9I2B0
names: Similarity
messages: Belongs to the thioredoxin family.

1176587:A8C56 RS05380
gene id: 1176587:A8C56_RS05380
uniprot id: A0A1A9HYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS01975
gene id: 1176587:A8C56_RS01975
uniprot id: A0A1A9HXW1
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS00230
gene id: 1176587:A8C56_RS00230
uniprot id: A0A1A9HW45
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1176587:A8C56 RS11095
gene id: 1176587:A8C56_RS11095
uniprot id: A0A1A9I444
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS08675
gene id: 1176587:A8C56_RS08675
uniprot id: A0A1A9I2X1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1176587:A8C56 RS00810
gene id: 1176587:A8C56_RS00810
uniprot id: A0A1A9HWE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1176587:A8C56 RS09865
gene id: 1176587:A8C56_RS09865
uniprot id: A0A1A9I3F9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1176587:A8C56 RS17775
gene id: 1176587:A8C56_RS17775
uniprot id: A0A1A9IBC3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1176587:A8C56 RS16320
gene id: 1176587:A8C56_RS16320
uniprot id: A0A1A9I3W9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1176587:A8C56 RS04010
gene id: 1176587:A8C56_RS04010
uniprot id: A0A1A9I0K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS16510
gene id: 1176587:A8C56_RS16510
uniprot id: A0A1A9I6N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1176587:A8C56 RS06290
gene id: 1176587:A8C56_RS06290
uniprot id: A0A1A9I1S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1176587:A8C56 RS08030
gene id: 1176587:A8C56_RS08030
uniprot id: A0A1A9HZV3
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS01720
gene id: 1176587:A8C56_RS01720
uniprot id: A0A1A9HX98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS23310
gene id: 1176587:A8C56_RS23310
uniprot id: A0A1A9I9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1176587:A8C56 RS18125
gene id: 1176587:A8C56_RS18125
uniprot id: A0A1A9I7X8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1176587:A8C56 RS17470
gene id: 1176587:A8C56_RS17470
uniprot id: A0A1A9I791
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1176587:A8C56 RS09700
gene id: 1176587:A8C56_RS09700
uniprot id: A0A1A9I2D5
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS06645
gene id: 1176587:A8C56_RS06645
uniprot id: A0A1A9HZ64
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS00870
gene id: 1176587:A8C56_RS00870
uniprot id: A0A1A9HY19
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1176587:A8C56 RS23145
gene id: 1176587:A8C56_RS23145
uniprot id: A0A1A9IAA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1176587:A8C56 RS03485
gene id: 1176587:A8C56_RS03485
uniprot id: A0A1A9HZD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1176587:A8C56 RS16855
gene id: 1176587:A8C56_RS16855
uniprot id: A0A1A9I796
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1176587:A8C56 RS19820
gene id: 1176587:A8C56_RS19820
uniprot id: A0A1A9I5U6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS04995
gene id: 1176587:A8C56_RS04995
uniprot id: A0A1A9I132
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1176587:A8C56 RS07760
gene id: 1176587:A8C56_RS07760
uniprot id: A0A1A9IAK1
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1176587:A8C56 RS19215
gene id: 1176587:A8C56_RS19215
uniprot id: A0A1A9I563
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1176587:A8C56 RS11070
gene id: 1176587:A8C56_RS11070
uniprot id: A0A1A9IBB5
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1176587:A8C56 RS11870
gene id: 1176587:A8C56_RS11870
uniprot id: A0A1A9I1Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1176587:A8C56 RS08465
gene id: 1176587:A8C56_RS08465
uniprot id: A0A1A9I0Z6
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1176587:A8C56 RS17740
gene id: 1176587:A8C56_RS17740
uniprot id: A0A1A9I785
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1176587:A8C56 RS10910
gene id: 1176587:A8C56_RS10910
uniprot id: A0A1A9I853
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1176587:A8C56 RS03925
gene id: 1176587:A8C56_RS03925
uniprot id: A0A1A9I111
names: Similarity
messages: Belongs to the threonine synthase family.

1176587:A8C56 RS11635
gene id: 1176587:A8C56_RS11635
uniprot id: A0A1A9I3A4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1176587:A8C56 RS22470
gene id: 1176587:A8C56_RS22470
uniprot id: A0A1A9I9I0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1176587:A8C56 RS00985
gene id: 1176587:A8C56_RS00985
uniprot id: A0A1A9HWH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1176587:A8C56 RS22615
gene id: 1176587:A8C56_RS22615
uniprot id: A0A1A9I9P9
names: Similarity
messages: Belongs to the sigma-54 factor family.

1176587:A8C56 RS11445
gene id: 1176587:A8C56_RS11445
uniprot id: A0A1A9I374
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1176587:A8C56 RS22695
gene id: 1176587:A8C56_RS22695
uniprot id: A0A1A9I7W0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1176587:A8C56 RS22835
gene id: 1176587:A8C56_RS22835
uniprot id: A0A1A9IA56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1176587:A8C56 RS08480
gene id: 1176587:A8C56_RS08480
uniprot id: A0A1A9I038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1176587:A8C56 RS17670
gene id: 1176587:A8C56_RS17670
uniprot id: A0A1A9I680
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS12080
gene id: 1176587:A8C56_RS12080
uniprot id: A0A1A9I1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1176587:A8C56 RS17225
gene id: 1176587:A8C56_RS17225
uniprot id: A0A1A9IBS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1176587:A8C56 RS00255
gene id: 1176587:A8C56_RS00255
uniprot id: A0A1A9HYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1176587:A8C56 RS23285
gene id: 1176587:A8C56_RS23285
uniprot id: A0A1A9I746
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1176587:A8C56 RS12030
gene id: 1176587:A8C56_RS12030
uniprot id: A0A1A9I1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS00315
gene id: 1176587:A8C56_RS00315
uniprot id: A0A1A9I7N9
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS00425
gene id: 1176587:A8C56_RS00425
uniprot id: A0A1A9HYU0
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS06060
gene id: 1176587:A8C56_RS06060
uniprot id: A0A1A9HZB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1176587:A8C56 RS19365
gene id: 1176587:A8C56_RS19365
uniprot id: A0A1A9I8J3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS17990
gene id: 1176587:A8C56_RS17990
uniprot id: A0A1A9I7I2
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS09370
gene id: 1176587:A8C56_RS09370
uniprot id: A0A1A9I369
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1176587:A8C56 RS17440
gene id: 1176587:A8C56_RS17440
uniprot id: A0A1A9I8S9
names: Similarity
messages: Belongs to the DprA/Smf family.

1176587:A8C56 RS12225
gene id: 1176587:A8C56_RS12225
uniprot id: A0A1A9I518
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1176587:A8C56 RS18985
gene id: 1176587:A8C56_RS18985
uniprot id: A0A1A9I619
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1176587:A8C56 RS04930
gene id: 1176587:A8C56_RS04930
uniprot id: A0A1A9HYE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1176587:A8C56 RS08435
gene id: 1176587:A8C56_RS08435
uniprot id: A0A1A9I2S8
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1176587:A8C56 RS01855
gene id: 1176587:A8C56_RS01855
uniprot id: A0A1A9HWV1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1176587:A8C56 RS19665
gene id: 1176587:A8C56_RS19665
uniprot id: A0A1A9I5L5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1176587:A8C56 RS12060
gene id: 1176587:A8C56_RS12060
uniprot id: A0A1A9I4J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1176587:A8C56 RS21890
gene id: 1176587:A8C56_RS21890
uniprot id: A0A1A9I6N3
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS01780
gene id: 1176587:A8C56_RS01780
uniprot id: A0A1A9HXA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS23255
gene id: 1176587:A8C56_RS23255
uniprot id: A0A1A9IA01
names: Similarity
messages: Belongs to the DinB family.

1176587:A8C56 RS06720
gene id: 1176587:A8C56_RS06720
uniprot id: A0A1A9I0V7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1176587:A8C56 RS11120
gene id: 1176587:A8C56_RS11120
uniprot id: A0A1A9I1F6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS16285
gene id: 1176587:A8C56_RS16285
uniprot id: A0A1A9I5H8
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS21945
gene id: 1176587:A8C56_RS21945
uniprot id: A0A1A9I7H6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS23130
gene id: 1176587:A8C56_RS23130
uniprot id: A0A1A9I9T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS22915
gene id: 1176587:A8C56_RS22915
uniprot id: A0A1A9I6Y3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS13840
gene id: 1176587:A8C56_RS13840
uniprot id: A0A1A9IB32
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS07205
gene id: 1176587:A8C56_RS07205
uniprot id: A0A1A9I0D0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1176587:A8C56 RS13475
gene id: 1176587:A8C56_RS13475
uniprot id: A0A1A9I590
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1176587:A8C56 RS15960
gene id: 1176587:A8C56_RS15960
uniprot id: A0A1A9IBE2
names: Similarity
messages: Belongs to the peptidase S13 family.

1176587:A8C56 RS01305
gene id: 1176587:A8C56_RS01305
uniprot id: A0A1A9HWK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1176587:A8C56 RS19825
gene id: 1176587:A8C56_RS19825
uniprot id: A0A1A9I8T6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS09945
gene id: 1176587:A8C56_RS09945
uniprot id: A0A1A9I3J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1176587:A8C56 RS09905
gene id: 1176587:A8C56_RS09905
uniprot id: A0A1A9I0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1176587:A8C56 RS06080
gene id: 1176587:A8C56_RS06080
uniprot id: A0A1A9HYX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1176587:A8C56 RS02290
gene id: 1176587:A8C56_RS02290
uniprot id: A0A1A9HZR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS00650
gene id: 1176587:A8C56_RS00650
uniprot id: A0A1A9HYX1
names: Similarity
messages: Belongs to the LOG family.

1176587:A8C56 RS02280
gene id: 1176587:A8C56_RS02280
uniprot id: A0A1A9HX27
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1176587:A8C56 RS23215
gene id: 1176587:A8C56_RS23215
uniprot id: A0A1A9I738
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1176587:A8C56 RS01195
gene id: 1176587:A8C56_RS01195
uniprot id: A0A1A9HZ68
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS03065
gene id: 1176587:A8C56_RS03065
uniprot id: A0A1A9I039
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1176587:A8C56 RS19955
gene id: 1176587:A8C56_RS19955
uniprot id: A0A1A9I5R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1176587:A8C56 RS07270
gene id: 1176587:A8C56_RS07270
uniprot id: A0A1A9I7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1176587:A8C56 RS07080
gene id: 1176587:A8C56_RS07080
uniprot id: A0A1A9I2H1
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS14305
gene id: 1176587:A8C56_RS14305
uniprot id: A0A1A9I3U2
names: Subcellular Location Annotation
messages: Cytoplasm

1176587:A8C56 RS17910
gene id: 1176587:A8C56_RS17910
uniprot id: A0A1A9I4K2
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS19455
gene id: 1176587:A8C56_RS19455
uniprot id: A0A1A9I8S2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1176587:A8C56 RS03570
gene id: 1176587:A8C56_RS03570
uniprot id: A0A1A9IAD1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1176587:A8C56 RS14940
gene id: 1176587:A8C56_RS14940
uniprot id: A0A1A9I455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS08730
gene id: 1176587:A8C56_RS08730
uniprot id: A0A1A9I2Z3
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1176587:A8C56 RS06365
gene id: 1176587:A8C56_RS06365
uniprot id: A0A1A9HZF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1176587:A8C56 RS20730
gene id: 1176587:A8C56_RS20730
uniprot id: A0A1A9I935
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS11930
gene id: 1176587:A8C56_RS11930
uniprot id: A0A1A9I1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS04540
gene id: 1176587:A8C56_RS04540
uniprot id: A0A1A9I1A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1176587:A8C56 RS19900
gene id: 1176587:A8C56_RS19900
uniprot id: A0A1A9I5K4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1176587:A8C56 RS10595
gene id: 1176587:A8C56_RS10595
uniprot id: A0A1A9I3V6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1176587:A8C56 RS21385
gene id: 1176587:A8C56_RS21385
uniprot id: A0A1A9I944
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS08300
gene id: 1176587:A8C56_RS08300
uniprot id: A0A1A9I2P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS15805
gene id: 1176587:A8C56_RS15805
uniprot id: A0A1A9I695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS20435
gene id: 1176587:A8C56_RS20435
uniprot id: A0A1A9I941
names: Similarity
messages: Belongs to the DSD1 family.

1176587:A8C56 RS09850
gene id: 1176587:A8C56_RS09850
uniprot id: A0A1A9I0R2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1176587:A8C56 RS21865
gene id: 1176587:A8C56_RS21865
uniprot id: A0A1A9I990
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS07180
gene id: 1176587:A8C56_RS07180
uniprot id: A0A1A9I264
names: Similarity
messages: Belongs to the SufE family.

1176587:A8C56 RS05165
gene id: 1176587:A8C56_RS05165
uniprot id: A0A1A9I182
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1176587:A8C56 RS10360
gene id: 1176587:A8C56_RS10360
uniprot id: A0A1A9I3R2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1176587:A8C56 RS09340
gene id: 1176587:A8C56_RS09340
uniprot id: A0A1A9I3K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1176587:A8C56 RS09935
gene id: 1176587:A8C56_RS09935
uniprot id: A0A1A9I3H0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS00140
gene id: 1176587:A8C56_RS00140
uniprot id: A0A1A9HWI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1176587:A8C56 RS09265
gene id: 1176587:A8C56_RS09265
uniprot id: A0A1A9I347
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS00110
gene id: 1176587:A8C56_RS00110
uniprot id: A0A1A9HW29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1176587:A8C56 RS00940
gene id: 1176587:A8C56_RS00940
uniprot id: A0A1A9HZ29
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1176587:A8C56 RS16125
gene id: 1176587:A8C56_RS16125
uniprot id: A0A1A9I3N2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1176587:A8C56 RS01760
gene id: 1176587:A8C56_RS01760
uniprot id: A0A1A9HZH3
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS10655
gene id: 1176587:A8C56_RS10655
uniprot id: A0A1A9I3X0
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS00160
gene id: 1176587:A8C56_RS00160
uniprot id: A0A1A9I956
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1176587:A8C56 RS06930
gene id: 1176587:A8C56_RS06930
uniprot id: A0A1A9HZD9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1176587:A8C56 RS07235
gene id: 1176587:A8C56_RS07235
uniprot id: A0A1A9I8V5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1176587:A8C56 RS13575
gene id: 1176587:A8C56_RS13575
uniprot id: A0A1A9I2L9
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS13980
gene id: 1176587:A8C56_RS13980
uniprot id: A0A1A9I4F7
names: Similarity
messages: Belongs to the arginase family.

1176587:A8C56 RS19810
gene id: 1176587:A8C56_RS19810
uniprot id: A0A1A9I8D2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1176587:A8C56 RS01480
gene id: 1176587:A8C56_RS01480
uniprot id: A0A1A9I7P3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS18260
gene id: 1176587:A8C56_RS18260
uniprot id: A0A1A9I4P9
names: Similarity
messages: Belongs to the Skp family.

1176587:A8C56 RS09640
gene id: 1176587:A8C56_RS09640
uniprot id: A0A1A9I0N3
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1176587:A8C56 RS20610
gene id: 1176587:A8C56_RS20610
uniprot id: A0A1A9I664
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1176587:A8C56 RS03300
gene id: 1176587:A8C56_RS03300
uniprot id: A0A1A9HZA5
names: Similarity
messages: Belongs to the CinA family.

1176587:A8C56 RS01325
gene id: 1176587:A8C56_RS01325
uniprot id: A0A1A9HZE2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1176587:A8C56 RS01425
gene id: 1176587:A8C56_RS01425
uniprot id: A0A1A9HZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS20910
gene id: 1176587:A8C56_RS20910
uniprot id: A0A1A9I8S0
names: Similarity
messages: Belongs to the peptidase C40 family.

1176587:A8C56 RS06300
gene id: 1176587:A8C56_RS06300
uniprot id: A0A1A9HZE6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS20490
gene id: 1176587:A8C56_RS20490
uniprot id: A0A1A9I951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS09200
gene id: 1176587:A8C56_RS09200
uniprot id: A0A1A9I871
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1176587:A8C56 RS16710
gene id: 1176587:A8C56_RS16710
uniprot id: A0A1A9I8V7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS16525
gene id: 1176587:A8C56_RS16525
uniprot id: A0A1A9I472
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1176587:A8C56 RS07500
gene id: 1176587:A8C56_RS07500
uniprot id: A0A1A9IAM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS06900
gene id: 1176587:A8C56_RS06900
uniprot id: A0A1A9I210
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1176587:A8C56 RS00090
gene id: 1176587:A8C56_RS00090
uniprot id: A0A1A9HZ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1176587:A8C56 RS22280
gene id: 1176587:A8C56_RS22280
uniprot id: A0A1A9I7P0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1176587:A8C56 RS23665
gene id: 1176587:A8C56_RS23665
uniprot id: A0A1A9I927
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS14250
gene id: 1176587:A8C56_RS14250
uniprot id: A0A1A9I603
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1176587:A8C56 RS21700
gene id: 1176587:A8C56_RS21700
uniprot id: A0A1A9I962
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS17345
gene id: 1176587:A8C56_RS17345
uniprot id: A0A1A9I615
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS01525
gene id: 1176587:A8C56_RS01525
uniprot id: A0A1A9HWP4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1176587:A8C56 RS15420
gene id: 1176587:A8C56_RS15420
uniprot id: A0A1A9I634
names: Similarity
messages: Belongs to the UPF0102 family.

1176587:A8C56 RS16330
gene id: 1176587:A8C56_RS16330
uniprot id: A0A1A9I3S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1176587:A8C56 RS24835
gene id: 1176587:A8C56_RS24835
uniprot id: A0A1A9I1E2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS06150
gene id: 1176587:A8C56_RS06150
uniprot id: A0A1A9I0M0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS00455
gene id: 1176587:A8C56_RS00455
uniprot id: A0A1A9HW85
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

1176587:A8C56 RS01100
gene id: 1176587:A8C56_RS01100
uniprot id: A0A1A9I7N3
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS00430
gene id: 1176587:A8C56_RS00430
uniprot id: A0A1A9HYS7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1176587:A8C56 RS02125
gene id: 1176587:A8C56_RS02125
uniprot id: A0A1A9HXH1
names: Similarity
messages: Belongs to the peptidase S66 family.

1176587:A8C56 RS16565
gene id: 1176587:A8C56_RS16565
uniprot id: A0A1A9I5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1176587:A8C56 RS16080
gene id: 1176587:A8C56_RS16080
uniprot id: A0A1A9I5D8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1176587:A8C56 RS18970
gene id: 1176587:A8C56_RS18970
uniprot id: A0A1A9I7Z1
names: Similarity
messages: Belongs to the pirin family.

1176587:A8C56 RS17050
gene id: 1176587:A8C56_RS17050
uniprot id: A0A1A9I544
names: Similarity
messages: Belongs to the peptidase C40 family.

1176587:A8C56 RS04975
gene id: 1176587:A8C56_RS04975
uniprot id: A0A1A9HYI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1176587:A8C56 RS01145
gene id: 1176587:A8C56_RS01145
uniprot id: A0A1A9HZ60
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS12675
gene id: 1176587:A8C56_RS12675
uniprot id: A0A1A9IB52
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS20175
gene id: 1176587:A8C56_RS20175
uniprot id: A0A1A9I8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1176587:A8C56 RS06795
gene id: 1176587:A8C56_RS06795
uniprot id: A0A1A9I1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1176587:A8C56 RS19090
gene id: 1176587:A8C56_RS19090
uniprot id: A0A1A9I8E3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1176587:A8C56 RS17600
gene id: 1176587:A8C56_RS17600
uniprot id: A0A1A9I4J2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1176587:A8C56 RS00965
gene id: 1176587:A8C56_RS00965
uniprot id: A0A1A9HXC8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1176587:A8C56 RS17095
gene id: 1176587:A8C56_RS17095
uniprot id: A0A1A9I7E0
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS06960
gene id: 1176587:A8C56_RS06960
uniprot id: A0A1A9I229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1176587:A8C56 RS22620
gene id: 1176587:A8C56_RS22620
uniprot id: A0A1A9I9L5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS05005
gene id: 1176587:A8C56_RS05005
uniprot id: A0A1A9I163
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1176587:A8C56 RS20410
gene id: 1176587:A8C56_RS20410
uniprot id: A0A1A9I8J6
names: Function
names: Subunit
messages: Homodimer.
messages: Represses transcription of the icaADBC operon necessary for biofilm production.

1176587:A8C56 RS17855
gene id: 1176587:A8C56_RS17855
uniprot id: A0A1A9I4I5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1176587:A8C56 RS03705
gene id: 1176587:A8C56_RS03705
uniprot id: A0A1A9I0W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1176587:A8C56 RS06320
gene id: 1176587:A8C56_RS06320
uniprot id: A0A1A9HZ41
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1176587:A8C56 RS01310
gene id: 1176587:A8C56_RS01310
uniprot id: A0A1A9HY86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1176587:A8C56 RS00095
gene id: 1176587:A8C56_RS00095
uniprot id: A0A1A9HWX6
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS20775
gene id: 1176587:A8C56_RS20775
uniprot id: A0A1A9I5Z1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

1176587:A8C56 RS00790
gene id: 1176587:A8C56_RS00790
uniprot id: A0A1A9HZF9
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS05795
gene id: 1176587:A8C56_RS05795
uniprot id: A0A1A9I1X2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1176587:A8C56 RS21775
gene id: 1176587:A8C56_RS21775
uniprot id: A0A1A9I6D9
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS09100
gene id: 1176587:A8C56_RS09100
uniprot id: A0A1A9I3G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1176587:A8C56 RS04235
gene id: 1176587:A8C56_RS04235
uniprot id: A0A1A9I0N5
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS18085
gene id: 1176587:A8C56_RS18085
uniprot id: A0A1A9I4L6
names: Similarity
messages: Belongs to the GARS family.

1176587:A8C56 RS04500
gene id: 1176587:A8C56_RS04500
uniprot id: A0A1A9HY89
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1176587:A8C56 RS12685
gene id: 1176587:A8C56_RS12685
uniprot id: A0A1A9I4X5
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS21900
gene id: 1176587:A8C56_RS21900
uniprot id: A0A1A9I6H7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1176587:A8C56 RS18880
gene id: 1176587:A8C56_RS18880
uniprot id: A0A1A9I502
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS11845
gene id: 1176587:A8C56_RS11845
uniprot id: A0A1A9I215
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1176587:A8C56 RS18215
gene id: 1176587:A8C56_RS18215
uniprot id: A0A1A9I6H0
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS00980
gene id: 1176587:A8C56_RS00980
uniprot id: A0A1A9I982
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1176587:A8C56 RS16025
gene id: 1176587:A8C56_RS16025
uniprot id: A0A1A9I3Z1
names: Similarity
messages: Belongs to the Skp family.

1176587:A8C56 RS14745
gene id: 1176587:A8C56_RS14745
uniprot id: A0A1A9I5U0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1176587:A8C56 RS05775
gene id: 1176587:A8C56_RS05775
uniprot id: A0A1A9I1J2
names: Similarity
messages: Belongs to the peptidase S9A family.

1176587:A8C56 RS13755
gene id: 1176587:A8C56_RS13755
uniprot id: A0A1A9I2Q3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1176587:A8C56 RS05235
gene id: 1176587:A8C56_RS05235
uniprot id: A0A1A9I1A0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1176587:A8C56 RS18780
gene id: 1176587:A8C56_RS18780
uniprot id: A0A1A9I4Y6
names: Similarity
messages: Belongs to the PrpD family.

1176587:A8C56 RS15415
gene id: 1176587:A8C56_RS15415
uniprot id: A0A1A9I541
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1176587:A8C56 RS21895
gene id: 1176587:A8C56_RS21895
uniprot id: A0A1A9I6F3
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS21830
gene id: 1176587:A8C56_RS21830
uniprot id: A0A1A9I6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS08035
gene id: 1176587:A8C56_RS08035
uniprot id: A0A1A9HZX2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1176587:A8C56 RS04110
gene id: 1176587:A8C56_RS04110
uniprot id: A0A1A9HYW4
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS17145
gene id: 1176587:A8C56_RS17145
uniprot id: A0A1A9I728
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS10570
gene id: 1176587:A8C56_RS10570
uniprot id: A0A1A9I141
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1176587:A8C56 RS19065
gene id: 1176587:A8C56_RS19065
uniprot id: A0A1A9I7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS17430
gene id: 1176587:A8C56_RS17430
uniprot id: A0A1A9I5B1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1176587:A8C56 RS20185
gene id: 1176587:A8C56_RS20185
uniprot id: A0A1A9I8J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1176587:A8C56 RS10935
gene id: 1176587:A8C56_RS10935
uniprot id: A0A1A9I184
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS05175
gene id: 1176587:A8C56_RS05175
uniprot id: A0A1A9HYY0
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1176587:A8C56 RS23305
gene id: 1176587:A8C56_RS23305
uniprot id: A0A1A9IA10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1176587:A8C56 RS05595
gene id: 1176587:A8C56_RS05595
uniprot id: A0A1A9HZ42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1176587:A8C56 RS16260
gene id: 1176587:A8C56_RS16260
uniprot id: A0A1A9I4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1176587:A8C56 RS20535
gene id: 1176587:A8C56_RS20535
uniprot id: A0A1A9I8L5
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS15520
gene id: 1176587:A8C56_RS15520
uniprot id: A0A1A9I3I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS16440
gene id: 1176587:A8C56_RS16440
uniprot id: A0A1A9I3T5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1176587:A8C56 RS00490
gene id: 1176587:A8C56_RS00490
uniprot id: A0A1A9HYZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS13060
gene id: 1176587:A8C56_RS13060
uniprot id: A0A1A9I2E1
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS16480
gene id: 1176587:A8C56_RS16480
uniprot id: A0A1A9I4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1176587:A8C56 RS12615
gene id: 1176587:A8C56_RS12615
uniprot id: A0A1A9I8F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS09680
gene id: 1176587:A8C56_RS09680
uniprot id: A0A1A9I1K7
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1176587:A8C56 RS11135
gene id: 1176587:A8C56_RS11135
uniprot id: A0A1A9I321
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS18090
gene id: 1176587:A8C56_RS18090
uniprot id: A0A1A9I4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1176587:A8C56 RS21630
gene id: 1176587:A8C56_RS21630
uniprot id: A0A1A9I837
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS15545
gene id: 1176587:A8C56_RS15545
uniprot id: A0A1A9I561
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1176587:A8C56 RS14795
gene id: 1176587:A8C56_RS14795
uniprot id: A0A1A9I5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1176587:A8C56 RS19020
gene id: 1176587:A8C56_RS19020
uniprot id: A0A1A9I800
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1176587:A8C56 RS11150
gene id: 1176587:A8C56_RS11150
uniprot id: A0A1A9I445
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS00885
gene id: 1176587:A8C56_RS00885
uniprot id: A0A1A9HZ65
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1176587:A8C56 RS20055
gene id: 1176587:A8C56_RS20055
uniprot id: A0A1A9I8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1176587:A8C56 RS06065
gene id: 1176587:A8C56_RS06065
uniprot id: A0A1A9I208
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1176587:A8C56 RS23385
gene id: 1176587:A8C56_RS23385
uniprot id: A0A1A9I995
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS03295
gene id: 1176587:A8C56_RS03295
uniprot id: A0A1A9HXJ2
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1176587:A8C56 RS20940
gene id: 1176587:A8C56_RS20940
uniprot id: A0A1A9I701
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1176587:A8C56 RS18280
gene id: 1176587:A8C56_RS18280
uniprot id: A0A1A9I7I5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS08180
gene id: 1176587:A8C56_RS08180
uniprot id: A0A1A9I2N8
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS07600
gene id: 1176587:A8C56_RS07600
uniprot id: A0A1A9I8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1176587:A8C56 RS06845
gene id: 1176587:A8C56_RS06845
uniprot id: A0A1A9I209
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS07515
gene id: 1176587:A8C56_RS07515
uniprot id: A0A1A9HZK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1176587:A8C56 RS05050
gene id: 1176587:A8C56_RS05050
uniprot id: A0A1A9I142
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1176587:A8C56 RS04970
gene id: 1176587:A8C56_RS04970
uniprot id: A0A1A9HZB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1176587:A8C56 RS13520
gene id: 1176587:A8C56_RS13520
uniprot id: A0A1A9I2G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS06520
gene id: 1176587:A8C56_RS06520
uniprot id: A0A1A9HZ44
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1176587:A8C56 RS04240
gene id: 1176587:A8C56_RS04240
uniprot id: A0A1A9I0P1
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS00135
gene id: 1176587:A8C56_RS00135
uniprot id: A0A1A9HYT7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1176587:A8C56 RS13800
gene id: 1176587:A8C56_RS13800
uniprot id: A0A1A9I5T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1176587:A8C56 RS13470
gene id: 1176587:A8C56_RS13470
uniprot id: A0A1A9I5A6
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1176587:A8C56 RS08120
gene id: 1176587:A8C56_RS08120
uniprot id: A0A1A9I2M9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1176587:A8C56 RS20765
gene id: 1176587:A8C56_RS20765
uniprot id: A0A1A9I644
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1176587:A8C56 RS09030
gene id: 1176587:A8C56_RS09030
uniprot id: A0A1A9I0R5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1176587:A8C56 RS15480
gene id: 1176587:A8C56_RS15480
uniprot id: A0A1A9I663
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1176587:A8C56 RS22635
gene id: 1176587:A8C56_RS22635
uniprot id: A0A1A9IA28
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS05555
gene id: 1176587:A8C56_RS05555
uniprot id: A0A1A9HYN8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1176587:A8C56 RS11990
gene id: 1176587:A8C56_RS11990
uniprot id: A0A1A9I3G7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1176587:A8C56 RS00210
gene id: 1176587:A8C56_RS00210
uniprot id: A0A1A9HYU7
names: Similarity
messages: Belongs to the peptidase S58 family.

1176587:A8C56 RS04340
gene id: 1176587:A8C56_RS04340
uniprot id: A0A1A9HZR3
names: Similarity
messages: Belongs to the DapA family.

1176587:A8C56 RS22650
gene id: 1176587:A8C56_RS22650
uniprot id: A0A1A9I6U5
names: Similarity
messages: Belongs to the YoeB family.

1176587:A8C56 RS20325
gene id: 1176587:A8C56_RS20325
uniprot id: A0A1A9I6Q4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1176587:A8C56 RS03850
gene id: 1176587:A8C56_RS03850
uniprot id: A0A1A9I0H7
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1176587:A8C56 RS09325
gene id: 1176587:A8C56_RS09325
uniprot id: A0A1A9I388
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1176587:A8C56 RS20945
gene id: 1176587:A8C56_RS20945
uniprot id: A0A1A9I679
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS06295
gene id: 1176587:A8C56_RS06295
uniprot id: A0A1A9I9K5
names: Subcellular Location Annotation
messages: Membrane

1176587:A8C56 RS22520
gene id: 1176587:A8C56_RS22520
uniprot id: A0A1A9I6Z2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1176587:A8C56 RS08275
gene id: 1176587:A8C56_RS08275
uniprot id: A0A1A9HZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS13935
gene id: 1176587:A8C56_RS13935
uniprot id: A0A1A9I319
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1176587:A8C56 RS01030
gene id: 1176587:A8C56_RS01030
uniprot id: A0A1A9HXD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS22735
gene id: 1176587:A8C56_RS22735
uniprot id: A0A1A9I8L9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1176587:A8C56 RS06095
gene id: 1176587:A8C56_RS06095
uniprot id: A0A1A9I1L2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1176587:A8C56 RS14430
gene id: 1176587:A8C56_RS14430
uniprot id: A0A1A9I310
names: Similarity
messages: Belongs to the YjdM family.

1176587:A8C56 RS07965
gene id: 1176587:A8C56_RS07965
uniprot id: A0A1A9I2X9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1176587:A8C56 RS11705
gene id: 1176587:A8C56_RS11705
uniprot id: A0A1A9I1M2
names: Similarity
messages: Belongs to the UPF0758 family.

1176587:A8C56 RS01185
gene id: 1176587:A8C56_RS01185
uniprot id: A0A1A9HWI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1176587:A8C56 RS09135
gene id: 1176587:A8C56_RS09135
uniprot id: A0A1A9I324
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1176587:A8C56 RS02085
gene id: 1176587:A8C56_RS02085
uniprot id: A0A1A9HXY1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1176587:A8C56 RS00510
gene id: 1176587:A8C56_RS00510
uniprot id: A0A1A9HW95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1176587:A8C56 RS19220
gene id: 1176587:A8C56_RS19220
uniprot id: A0A1A9I573
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

1176587:A8C56 RS12170
gene id: 1176587:A8C56_RS12170
uniprot id: A0A1A9I1V5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS05985
gene id: 1176587:A8C56_RS05985
uniprot id: A0A1A9HZA0
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1176587:A8C56 RS10260
gene id: 1176587:A8C56_RS10260
uniprot id: A0A1A9I1B5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1176587:A8C56 RS03220
gene id: 1176587:A8C56_RS03220
uniprot id: A0A1A9HXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1176587:A8C56 RS13925
gene id: 1176587:A8C56_RS13925
uniprot id: A0A1A9I5H9
names: Similarity
messages: Belongs to the Lgt family.

1176587:A8C56 RS23735
gene id: 1176587:A8C56_RS23735
uniprot id: A0A1A9I7L8
names: Similarity
messages: Belongs to the sulfatase family.

1176587:A8C56 RS17730
gene id: 1176587:A8C56_RS17730
uniprot id: A0A1A9I689
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1176587:A8C56 RS19550
gene id: 1176587:A8C56_RS19550
uniprot id: A0A1A9I5D6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS17875
gene id: 1176587:A8C56_RS17875
uniprot id: A0A1A9I8T8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1176587:A8C56 RS06420
gene id: 1176587:A8C56_RS06420
uniprot id: A0A1A9I0Q6
names: Similarity
messages: Belongs to the BshC family.

1176587:A8C56 RS14820
gene id: 1176587:A8C56_RS14820
uniprot id: A0A1A9I6A7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1176587:A8C56 RS17305
gene id: 1176587:A8C56_RS17305
uniprot id: A0A1A9I719
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1176587:A8C56 RS06865
gene id: 1176587:A8C56_RS06865
uniprot id: A0A1A9I071
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS05720
gene id: 1176587:A8C56_RS05720
uniprot id: A0A1A9HZQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS06730
gene id: 1176587:A8C56_RS06730
uniprot id: A0A1A9I1X8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1176587:A8C56 RS20400
gene id: 1176587:A8C56_RS20400
uniprot id: A0A1A9IBZ8
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS17845
gene id: 1176587:A8C56_RS17845
uniprot id: A0A1A9I4M8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1176587:A8C56 RS05335
gene id: 1176587:A8C56_RS05335
uniprot id: A0A1A9I085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1176587:A8C56 RS02355
gene id: 1176587:A8C56_RS02355
uniprot id: A0A1A9HZS0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1176587:A8C56 RS14505
gene id: 1176587:A8C56_RS14505
uniprot id: A0A1A9I5Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1176587:A8C56 RS13565
gene id: 1176587:A8C56_RS13565
uniprot id: A0A1A9I5M8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1176587:A8C56 RS23435
gene id: 1176587:A8C56_RS23435
uniprot id: A0A1A9I7H1
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS06190
gene id: 1176587:A8C56_RS06190
uniprot id: A0A1A9HZW8
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1176587:A8C56 RS11720
gene id: 1176587:A8C56_RS11720
uniprot id: A0A1A9I4E8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1176587:A8C56 RS06345
gene id: 1176587:A8C56_RS06345
uniprot id: A0A1A9I0P6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1176587:A8C56 RS20485
gene id: 1176587:A8C56_RS20485
uniprot id: A0A1A9I646
names: Similarity
messages: Belongs to the SusD family.

1176587:A8C56 RS19770
gene id: 1176587:A8C56_RS19770
uniprot id: A0A1A9I5U3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.