1166018:FAES RS18090
gene id: 1166018:FAES_RS18090
uniprot id: I0KBS7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1166018:FAES RS07630
gene id: 1166018:FAES_RS07630
uniprot id: I0K5X3
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1166018:FAES RS27190
gene id: 1166018:FAES_RS27190
uniprot id: I0KGS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1166018:FAES RS23450
gene id: 1166018:FAES_RS23450
uniprot id: I0KEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1166018:FAES RS22780
gene id: 1166018:FAES_RS22780
uniprot id: I0KE93
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1166018:FAES RS14815
gene id: 1166018:FAES_RS14815
uniprot id: I0K9Z3
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1166018:FAES RS22880
gene id: 1166018:FAES_RS22880
uniprot id: I0KEB4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS03170
gene id: 1166018:FAES_RS03170
uniprot id: I0K3E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1166018:FAES RS23595
gene id: 1166018:FAES_RS23595
uniprot id: I0KEQ6
names: Similarity
messages: Belongs to the NDK family.

1166018:FAES RS22515
gene id: 1166018:FAES_RS22515
uniprot id: I0KE39
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS00055
gene id: 1166018:FAES_RS00055
uniprot id: I0K1M2
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1166018:FAES RS06015
gene id: 1166018:FAES_RS06015
uniprot id: I0K507
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1166018:FAES RS17350
gene id: 1166018:FAES_RS17350
uniprot id: I0KBD2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS09970
gene id: 1166018:FAES_RS09970
uniprot id: I0K777
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1166018:FAES RS00870
gene id: 1166018:FAES_RS00870
uniprot id: I0K235
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS27195
gene id: 1166018:FAES_RS27195
uniprot id: I0KGS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1166018:FAES RS05345
gene id: 1166018:FAES_RS05345
uniprot id: I0K4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1166018:FAES RS24945
gene id: 1166018:FAES_RS24945
uniprot id: I0KFH7
names: Similarity
messages: Belongs to the YjiK family.

1166018:FAES RS02650
gene id: 1166018:FAES_RS02650
uniprot id: I0K340
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS04730
gene id: 1166018:FAES_RS04730
uniprot id: I0K4A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1166018:FAES RS00620
gene id: 1166018:FAES_RS00620
uniprot id: I0K1Y4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS27120
gene id: 1166018:FAES_RS27120
uniprot id: I0KGQ7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1166018:FAES RS22085
gene id: 1166018:FAES_RS22085
uniprot id: I0KDV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1166018:FAES RS03915
gene id: 1166018:FAES_RS03915
uniprot id: I0K3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1166018:FAES RS04720
gene id: 1166018:FAES_RS04720
uniprot id: I0K4A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1166018:FAES RS26700
gene id: 1166018:FAES_RS26700
uniprot id: I0KGH3
names: Similarity
messages: Belongs to the aspartokinase family.

1166018:FAES RS02035
gene id: 1166018:FAES_RS02035
uniprot id: I0K2S1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1166018:FAES RS09515
gene id: 1166018:FAES_RS09515
uniprot id: I0K6Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS14800
gene id: 1166018:FAES_RS14800
uniprot id: I0K9Z0
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1166018:FAES RS05475
gene id: 1166018:FAES_RS05475
uniprot id: I0K4P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1166018:FAES RS02025
gene id: 1166018:FAES_RS02025
uniprot id: I0K2R9
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1166018:FAES RS00460
gene id: 1166018:FAES_RS00460
uniprot id: I0K1V2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS11860
gene id: 1166018:FAES_RS11860
uniprot id: I0K897
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1166018:FAES RS05850
gene id: 1166018:FAES_RS05850
uniprot id: I0K4X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS02160
gene id: 1166018:FAES_RS02160
uniprot id: I0K2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1166018:FAES RS18145
gene id: 1166018:FAES_RS18145
uniprot id: I0KBT8
names: Similarity
messages: Belongs to the Dps family.

1166018:FAES RS01090
gene id: 1166018:FAES_RS01090
uniprot id: I0K279
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS15410
gene id: 1166018:FAES_RS15410
uniprot id: I0KAB1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS13745
gene id: 1166018:FAES_RS13745
uniprot id: I0K9C7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1166018:FAES RS13055
gene id: 1166018:FAES_RS13055
uniprot id: I0K8Y8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS18985
gene id: 1166018:FAES_RS18985
uniprot id: I0KC93
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS01500
gene id: 1166018:FAES_RS01500
uniprot id: I0K2F8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1166018:FAES RS28760
gene id: 1166018:FAES_RS28760
uniprot id: I0KHN1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS12215
gene id: 1166018:FAES_RS12215
uniprot id: I0K8G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1166018:FAES RS29165
gene id: 1166018:FAES_RS29165
uniprot id: I0KCF7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1166018:FAES RS15115
gene id: 1166018:FAES_RS15115
uniprot id: I0KA52
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS17175
gene id: 1166018:FAES_RS17175
uniprot id: I0KB97
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1166018:FAES RS03975
gene id: 1166018:FAES_RS03975
uniprot id: I0K3V6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS00905
gene id: 1166018:FAES_RS00905
uniprot id: I0K242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1166018:FAES RS19330
gene id: 1166018:FAES_RS19330
uniprot id: I0KCF4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS02770
gene id: 1166018:FAES_RS02770
uniprot id: I0K366
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1166018:FAES RS05945
gene id: 1166018:FAES_RS05945
uniprot id: I0K4Z3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1166018:FAES RS07430
gene id: 1166018:FAES_RS07430
uniprot id: I0K5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS17135
gene id: 1166018:FAES_RS17135
uniprot id: I0KB89
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1166018:FAES RS00115
gene id: 1166018:FAES_RS00115
uniprot id: I0K1N4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1166018:FAES RS25175
gene id: 1166018:FAES_RS25175
uniprot id: I0KFM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1166018:FAES RS18920
gene id: 1166018:FAES_RS18920
uniprot id: I0KC80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1166018:FAES RS02170
gene id: 1166018:FAES_RS02170
uniprot id: I0K2U8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS19670
gene id: 1166018:FAES_RS19670
uniprot id: I0KCM2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS25925
gene id: 1166018:FAES_RS25925
uniprot id: I0KG19
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1166018:FAES RS10850
gene id: 1166018:FAES_RS10850
uniprot id: I0K7Q5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS21455
gene id: 1166018:FAES_RS21455
uniprot id: I0KDI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1166018:FAES RS17910
gene id: 1166018:FAES_RS17910
uniprot id: I0KBP2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS11340
gene id: 1166018:FAES_RS11340
uniprot id: I0K7Z9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1166018:FAES RS06505
gene id: 1166018:FAES_RS06505
uniprot id: I0K5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1166018:FAES RS24365
gene id: 1166018:FAES_RS24365
uniprot id: I0KF63
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS17645
gene id: 1166018:FAES_RS17645
uniprot id: I0KBJ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1166018:FAES RS25260
gene id: 1166018:FAES_RS25260
uniprot id: I0KFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS26805
gene id: 1166018:FAES_RS26805
uniprot id: I0KGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1166018:FAES RS26730
gene id: 1166018:FAES_RS26730
uniprot id: I0KGH9
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1166018:FAES RS15010
gene id: 1166018:FAES_RS15010
uniprot id: I0KA33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS27185
gene id: 1166018:FAES_RS27185
uniprot id: I0KGS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1166018:FAES RS05385
gene id: 1166018:FAES_RS05385
uniprot id: I0K4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS01455
gene id: 1166018:FAES_RS01455
uniprot id: I0K2E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1166018:FAES RS22725
gene id: 1166018:FAES_RS22725
uniprot id: I0KE81
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS14485
gene id: 1166018:FAES_RS14485
uniprot id: I0K9S9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS00060
gene id: 1166018:FAES_RS00060
uniprot id: I0K1M3
names: Similarity
messages: Belongs to the fructosamine kinase family.

1166018:FAES RS14385
gene id: 1166018:FAES_RS14385
uniprot id: I0K9Q9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS15330
gene id: 1166018:FAES_RS15330
uniprot id: I0KA95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS11730
gene id: 1166018:FAES_RS11730
uniprot id: I0K872
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1166018:FAES RS13065
gene id: 1166018:FAES_RS13065
uniprot id: I0K8Z0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1166018:FAES RS12125
gene id: 1166018:FAES_RS12125
uniprot id: I0K8F1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS10470
gene id: 1166018:FAES_RS10470
uniprot id: I0K7H9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1166018:FAES RS05030
gene id: 1166018:FAES_RS05030
uniprot id: I0K4G3
names: Similarity
messages: Belongs to the UPF0162 family.

1166018:FAES RS22770
gene id: 1166018:FAES_RS22770
uniprot id: I0KE90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1166018:FAES RS05465
gene id: 1166018:FAES_RS05465
uniprot id: I0K4P7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1166018:FAES RS07360
gene id: 1166018:FAES_RS07360
uniprot id: I0K5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1166018:FAES RS21990
gene id: 1166018:FAES_RS21990
uniprot id: I0KDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS08580
gene id: 1166018:FAES_RS08580
uniprot id: I0K6G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1166018:FAES RS02080
gene id: 1166018:FAES_RS02080
uniprot id: I0K2T0
names: Subcellular Location Annotation
messages: Cytoplasm

1166018:FAES RS23515
gene id: 1166018:FAES_RS23515
uniprot id: I0KEN9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1166018:FAES RS13285
gene id: 1166018:FAES_RS13285
uniprot id: I0K933
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS06700
gene id: 1166018:FAES_RS06700
uniprot id: I0K5E4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1166018:FAES RS13675
gene id: 1166018:FAES_RS13675
uniprot id: I0K9B3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS09510
gene id: 1166018:FAES_RS09510
uniprot id: I0K6Y4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1166018:FAES RS02075
gene id: 1166018:FAES_RS02075
uniprot id: I0K2S9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS07785
gene id: 1166018:FAES_RS07785
uniprot id: I0K606
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS10305
gene id: 1166018:FAES_RS10305
uniprot id: I0K7E5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS27760
gene id: 1166018:FAES_RS27760
uniprot id: I0KH33
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1166018:FAES RS04110
gene id: 1166018:FAES_RS04110
uniprot id: I0K3Y3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1166018:FAES RS27890
gene id: 1166018:FAES_RS27890
uniprot id: I0KH59
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

1166018:FAES RS22155
gene id: 1166018:FAES_RS22155
uniprot id: I0KDW9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1166018:FAES RS08440
gene id: 1166018:FAES_RS08440
uniprot id: I0K6C9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS15610
gene id: 1166018:FAES_RS15610
uniprot id: I0KAF0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1166018:FAES RS18810
gene id: 1166018:FAES_RS18810
uniprot id: I0KC57
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1166018:FAES RS07025
gene id: 1166018:FAES_RS07025
uniprot id: I0K5K6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1166018:FAES RS01420
gene id: 1166018:FAES_RS01420
uniprot id: I0K2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

1166018:FAES RS20985
gene id: 1166018:FAES_RS20985
uniprot id: I0KD89
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1166018:FAES RS01075
gene id: 1166018:FAES_RS01075
uniprot id: I0K276
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS15990
gene id: 1166018:FAES_RS15990
uniprot id: I0KAM7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS24880
gene id: 1166018:FAES_RS24880
uniprot id: I0KFG5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS21410
gene id: 1166018:FAES_RS21410
uniprot id: I0KDH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1166018:FAES RS25720
gene id: 1166018:FAES_RS25720
uniprot id: I0KFX7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1166018:FAES RS14035
gene id: 1166018:FAES_RS14035
uniprot id: I0K9I5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS27145
gene id: 1166018:FAES_RS27145
uniprot id: I0KGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1166018:FAES RS21545
gene id: 1166018:FAES_RS21545
uniprot id: I0KDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1166018:FAES RS12755
gene id: 1166018:FAES_RS12755
uniprot id: I0K8S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS05365
gene id: 1166018:FAES_RS05365
uniprot id: I0K4N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1166018:FAES RS26810
gene id: 1166018:FAES_RS26810
uniprot id: I0KGJ4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1166018:FAES RS08355
gene id: 1166018:FAES_RS08355
uniprot id: I0K6B7
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS19760
gene id: 1166018:FAES_RS19760
uniprot id: I0KCN7
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1166018:FAES RS17990
gene id: 1166018:FAES_RS17990
uniprot id: I0KBQ6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS22170
gene id: 1166018:FAES_RS22170
uniprot id: I0KDX2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1166018:FAES RS14135
gene id: 1166018:FAES_RS14135
uniprot id: I0K9K7
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS22115
gene id: 1166018:FAES_RS22115
uniprot id: I0KDW1
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1166018:FAES RS23710
gene id: 1166018:FAES_RS23710
uniprot id: I0KET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1166018:FAES RS22835
gene id: 1166018:FAES_RS22835
uniprot id: I0KEA5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1166018:FAES RS18295
gene id: 1166018:FAES_RS18295
uniprot id: I0KBW8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1166018:FAES RS02040
gene id: 1166018:FAES_RS02040
uniprot id: I0K2S2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1166018:FAES RS20315
gene id: 1166018:FAES_RS20315
uniprot id: I0KCY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

1166018:FAES RS25560
gene id: 1166018:FAES_RS25560
uniprot id: I0KFU6
names: Similarity
messages: Belongs to the peptidase S8 family.

1166018:FAES RS17430
gene id: 1166018:FAES_RS17430
uniprot id: I0KBE8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1166018:FAES RS27650
gene id: 1166018:FAES_RS27650
uniprot id: I0KH13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1166018:FAES RS15045
gene id: 1166018:FAES_RS15045
uniprot id: I0KA39
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1166018:FAES RS25955
gene id: 1166018:FAES_RS25955
uniprot id: I0KG24
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS21830
gene id: 1166018:FAES_RS21830
uniprot id: I0KDQ2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1166018:FAES RS04485
gene id: 1166018:FAES_RS04485
uniprot id: I0K460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1166018:FAES RS22950
gene id: 1166018:FAES_RS22950
uniprot id: I0KEC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1166018:FAES RS28000
gene id: 1166018:FAES_RS28000
uniprot id: I0KH81
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS12285
gene id: 1166018:FAES_RS12285
uniprot id: I0K8I2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1166018:FAES RS06765
gene id: 1166018:FAES_RS06765
uniprot id: I0K5F8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1166018:FAES RS24690
gene id: 1166018:FAES_RS24690
uniprot id: I0KFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS09655
gene id: 1166018:FAES_RS09655
uniprot id: I0K713
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1166018:FAES RS25230
gene id: 1166018:FAES_RS25230
uniprot id: I0KFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1166018:FAES RS15335
gene id: 1166018:FAES_RS15335
uniprot id: I0KA96
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS02155
gene id: 1166018:FAES_RS02155
uniprot id: I0K2U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1166018:FAES RS04210
gene id: 1166018:FAES_RS04210
uniprot id: I0K402
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1166018:FAES RS21460
gene id: 1166018:FAES_RS21460
uniprot id: I0KDI1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS25655
gene id: 1166018:FAES_RS25655
uniprot id: I0KFW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1166018:FAES RS12920
gene id: 1166018:FAES_RS12920
uniprot id: I0K8W0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1166018:FAES RS00140
gene id: 1166018:FAES_RS00140
uniprot id: I0K1N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1166018:FAES RS15460
gene id: 1166018:FAES_RS15460
uniprot id: I0KAC1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS10040
gene id: 1166018:FAES_RS10040
uniprot id: I0K790
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1166018:FAES RS18055
gene id: 1166018:FAES_RS18055
uniprot id: I0KBR9
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS19720
gene id: 1166018:FAES_RS19720
uniprot id: I0KCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1166018:FAES RS22045
gene id: 1166018:FAES_RS22045
uniprot id: I0KDU7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1166018:FAES RS17305
gene id: 1166018:FAES_RS17305
uniprot id: I0KBC3
names: Similarity
messages: Belongs to the histone deacetylase family.

1166018:FAES RS21350
gene id: 1166018:FAES_RS21350
uniprot id: I0KDG0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS01900
gene id: 1166018:FAES_RS01900
uniprot id: I0K2P1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS01670
gene id: 1166018:FAES_RS01670
uniprot id: I0K2J3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS21125
gene id: 1166018:FAES_RS21125
uniprot id: I0KDB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1166018:FAES RS21080
gene id: 1166018:FAES_RS21080
uniprot id: I0KDA8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS22285
gene id: 1166018:FAES_RS22285
uniprot id: I0KDZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1166018:FAES RS19360
gene id: 1166018:FAES_RS19360
uniprot id: I0KCG0
names: Similarity
messages: Belongs to the ArsC family.

1166018:FAES RS27150
gene id: 1166018:FAES_RS27150
uniprot id: I0KGR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1166018:FAES RS00310
gene id: 1166018:FAES_RS00310
uniprot id: I0K1S3
names: Function
messages: May be involved in the biogenesis of curli organelles.

1166018:FAES RS23530
gene id: 1166018:FAES_RS23530
uniprot id: I0KEP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1166018:FAES RS18855
gene id: 1166018:FAES_RS18855
uniprot id: I0KC67
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1166018:FAES RS03925
gene id: 1166018:FAES_RS03925
uniprot id: I0K3U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1166018:FAES RS14850
gene id: 1166018:FAES_RS14850
uniprot id: I0KA00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1166018:FAES RS14015
gene id: 1166018:FAES_RS14015
uniprot id: I0K9I1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS23360
gene id: 1166018:FAES_RS23360
uniprot id: I0KEK8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS07915
gene id: 1166018:FAES_RS07915
uniprot id: I0K633
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1166018:FAES RS04255
gene id: 1166018:FAES_RS04255
uniprot id: I0K411
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1166018:FAES RS27215
gene id: 1166018:FAES_RS27215
uniprot id: I0KGS7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1166018:FAES RS27235
gene id: 1166018:FAES_RS27235
uniprot id: I0KGT1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1166018:FAES RS04645
gene id: 1166018:FAES_RS04645
uniprot id: I0K490
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS26515
gene id: 1166018:FAES_RS26515
uniprot id: I0KGD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS04960
gene id: 1166018:FAES_RS04960
uniprot id: I0K4F1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1166018:FAES RS14450
gene id: 1166018:FAES_RS14450
uniprot id: I0K9S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1166018:FAES RS23205
gene id: 1166018:FAES_RS23205
uniprot id: I0KEI0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1166018:FAES RS14945
gene id: 1166018:FAES_RS14945
uniprot id: I0KA20
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1166018:FAES RS10365
gene id: 1166018:FAES_RS10365
uniprot id: I0K7F7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1166018:FAES RS28785
gene id: 1166018:FAES_RS28785
uniprot id: I0KHN6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS02405
gene id: 1166018:FAES_RS02405
uniprot id: I0K2Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS24650
gene id: 1166018:FAES_RS24650
uniprot id: I0KFC0
names: Subcellular Location Annotation
messages: Secreted

1166018:FAES RS14820
gene id: 1166018:FAES_RS14820
uniprot id: I0K9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1166018:FAES RS05790
gene id: 1166018:FAES_RS05790
uniprot id: I0K4W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1166018:FAES RS16990
gene id: 1166018:FAES_RS16990
uniprot id: I0KB69
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1166018:FAES RS25770
gene id: 1166018:FAES_RS25770
uniprot id: I0KFY7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1166018:FAES RS05420
gene id: 1166018:FAES_RS05420
uniprot id: I0K4P2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS25220
gene id: 1166018:FAES_RS25220
uniprot id: I0KFN0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS04575
gene id: 1166018:FAES_RS04575
uniprot id: I0K478
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS18865
gene id: 1166018:FAES_RS18865
uniprot id: I0KC69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1166018:FAES RS19270
gene id: 1166018:FAES_RS19270
uniprot id: I0KCE2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1166018:FAES RS25345
gene id: 1166018:FAES_RS25345
uniprot id: I0KFQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1166018:FAES RS17955
gene id: 1166018:FAES_RS17955
uniprot id: I0KBQ0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS07235
gene id: 1166018:FAES_RS07235
uniprot id: I0K5P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1166018:FAES RS00485
gene id: 1166018:FAES_RS00485
uniprot id: I0K1V7
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS00265
gene id: 1166018:FAES_RS00265
uniprot id: I0K1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1166018:FAES RS03840
gene id: 1166018:FAES_RS03840
uniprot id: I0K3T0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1166018:FAES RS15740
gene id: 1166018:FAES_RS15740
uniprot id: I0KAH7
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS18825
gene id: 1166018:FAES_RS18825
uniprot id: I0KC60
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1166018:FAES RS20915
gene id: 1166018:FAES_RS20915
uniprot id: I0KD74
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1166018:FAES RS22005
gene id: 1166018:FAES_RS22005
uniprot id: I0KDT9
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS06915
gene id: 1166018:FAES_RS06915
uniprot id: I0K5I4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1166018:FAES RS26975
gene id: 1166018:FAES_RS26975
uniprot id: I0KGM8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS24645
gene id: 1166018:FAES_RS24645
uniprot id: I0KFB9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1166018:FAES RS05895
gene id: 1166018:FAES_RS05895
uniprot id: I0K4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS21520
gene id: 1166018:FAES_RS21520
uniprot id: I0KDJ3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS02725
gene id: 1166018:FAES_RS02725
uniprot id: I0K356
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1166018:FAES RS23215
gene id: 1166018:FAES_RS23215
uniprot id: I0KEI2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS21330
gene id: 1166018:FAES_RS21330
uniprot id: I0KDF6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1166018:FAES RS24480
gene id: 1166018:FAES_RS24480
uniprot id: I0KF86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1166018:FAES RS27490
gene id: 1166018:FAES_RS27490
uniprot id: I0KGY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1166018:FAES RS27105
gene id: 1166018:FAES_RS27105
uniprot id: I0KGQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1166018:FAES RS07585
gene id: 1166018:FAES_RS07585
uniprot id: I0K5W4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS23295
gene id: 1166018:FAES_RS23295
uniprot id: I0KEJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS07860
gene id: 1166018:FAES_RS07860
uniprot id: I0K622
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS14785
gene id: 1166018:FAES_RS14785
uniprot id: I0K9Y7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1166018:FAES RS08685
gene id: 1166018:FAES_RS08685
uniprot id: I0K6I1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1166018:FAES RS11405
gene id: 1166018:FAES_RS11405
uniprot id: I0K814
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS07465
gene id: 1166018:FAES_RS07465
uniprot id: I0K5U2
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1166018:FAES RS21155
gene id: 1166018:FAES_RS21155
uniprot id: I0KDC3
names: Similarity
messages: Belongs to the peptidase C40 family.

1166018:FAES RS05515
gene id: 1166018:FAES_RS05515
uniprot id: I0K4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1166018:FAES RS00325
gene id: 1166018:FAES_RS00325
uniprot id: I0K1S6
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1166018:FAES RS08510
gene id: 1166018:FAES_RS08510
uniprot id: I0K6E5
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS07350
gene id: 1166018:FAES_RS07350
uniprot id: I0K5R8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1166018:FAES RS27560
gene id: 1166018:FAES_RS27560
uniprot id: I0KGZ6
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1166018:FAES RS10585
gene id: 1166018:FAES_RS10585
uniprot id: I0K7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane

1166018:FAES RS05980
gene id: 1166018:FAES_RS05980
uniprot id: I0K500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1166018:FAES RS22210
gene id: 1166018:FAES_RS22210
uniprot id: I0KDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS03795
gene id: 1166018:FAES_RS03795
uniprot id: I0K3S0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS24355
gene id: 1166018:FAES_RS24355
uniprot id: I0KF61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1166018:FAES RS06845
gene id: 1166018:FAES_RS06845
uniprot id: I0K5H0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1166018:FAES RS10325
gene id: 1166018:FAES_RS10325
uniprot id: I0K7E9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS12150
gene id: 1166018:FAES_RS12150
uniprot id: I0K8F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1166018:FAES RS03810
gene id: 1166018:FAES_RS03810
uniprot id: I0K3S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS26850
gene id: 1166018:FAES_RS26850
uniprot id: I0KGK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1166018:FAES RS13920
gene id: 1166018:FAES_RS13920
uniprot id: I0K9G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1166018:FAES RS23540
gene id: 1166018:FAES_RS23540
uniprot id: I0KEP4
names: Similarity
messages: Belongs to the Skp family.

1166018:FAES RS03865
gene id: 1166018:FAES_RS03865
uniprot id: I0K3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS21205
gene id: 1166018:FAES_RS21205
uniprot id: I0KDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS23445
gene id: 1166018:FAES_RS23445
uniprot id: I0KEM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1166018:FAES RS23560
gene id: 1166018:FAES_RS23560
uniprot id: I0KEP8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS11065
gene id: 1166018:FAES_RS11065
uniprot id: I0K7U4
names: Similarity
messages: Belongs to the peptidase C56 family.

1166018:FAES RS13135
gene id: 1166018:FAES_RS13135
uniprot id: I0K903
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS25735
gene id: 1166018:FAES_RS25735
uniprot id: I0KFY0
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS21400
gene id: 1166018:FAES_RS21400
uniprot id: I0KDG8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1166018:FAES RS06100
gene id: 1166018:FAES_RS06100
uniprot id: I0K524
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1166018:FAES RS03855
gene id: 1166018:FAES_RS03855
uniprot id: I0K3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS25920
gene id: 1166018:FAES_RS25920
uniprot id: I0KG18
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1166018:FAES RS25540
gene id: 1166018:FAES_RS25540
uniprot id: I0KFU2
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

1166018:FAES RS26770
gene id: 1166018:FAES_RS26770
uniprot id: I0KGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS13880
gene id: 1166018:FAES_RS13880
uniprot id: I0K9F2
names: Similarity
messages: Belongs to the peptidase M24B family.

1166018:FAES RS28640
gene id: 1166018:FAES_RS28640
uniprot id: I0KHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1166018:FAES RS12970
gene id: 1166018:FAES_RS12970
uniprot id: I0K8X1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS25740
gene id: 1166018:FAES_RS25740
uniprot id: I0KFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS14895
gene id: 1166018:FAES_RS14895
uniprot id: I0KA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1166018:FAES RS21525
gene id: 1166018:FAES_RS21525
uniprot id: I0KDJ4
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS01080
gene id: 1166018:FAES_RS01080
uniprot id: I0K277
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS08235
gene id: 1166018:FAES_RS08235
uniprot id: I0K695
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1166018:FAES RS23925
gene id: 1166018:FAES_RS23925
uniprot id: I0KEX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1166018:FAES RS23015
gene id: 1166018:FAES_RS23015
uniprot id: I0KEE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1166018:FAES RS18085
gene id: 1166018:FAES_RS18085
uniprot id: I0KBS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1166018:FAES RS24350
gene id: 1166018:FAES_RS24350
uniprot id: I0KF60
names: Subcellular Location Annotation
messages: Cell inner membrane

1166018:FAES RS10330
gene id: 1166018:FAES_RS10330
uniprot id: I0K7F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1166018:FAES RS10360
gene id: 1166018:FAES_RS10360
uniprot id: I0K7F6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS06320
gene id: 1166018:FAES_RS06320
uniprot id: I0K566
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1166018:FAES RS07610
gene id: 1166018:FAES_RS07610
uniprot id: I0K5W9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1166018:FAES RS12080
gene id: 1166018:FAES_RS12080
uniprot id: I0K8E2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS11205
gene id: 1166018:FAES_RS11205
uniprot id: I0K7X1
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1166018:FAES RS03275
gene id: 1166018:FAES_RS03275
uniprot id: I0K3G6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS12050
gene id: 1166018:FAES_RS12050
uniprot id: I0K8D6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1166018:FAES RS15530
gene id: 1166018:FAES_RS15530
uniprot id: I0KAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1166018:FAES RS22635
gene id: 1166018:FAES_RS22635
uniprot id: I0KE65
names: Similarity
messages: Belongs to the proline racemase family.

1166018:FAES RS07410
gene id: 1166018:FAES_RS07410
uniprot id: I0K5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS11935
gene id: 1166018:FAES_RS11935
uniprot id: I0K8B2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS15835
gene id: 1166018:FAES_RS15835
uniprot id: I0KAJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1166018:FAES RS27335
gene id: 1166018:FAES_RS27335
uniprot id: I0KGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1166018:FAES RS11290
gene id: 1166018:FAES_RS11290
uniprot id: I0K7Y9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1166018:FAES RS01610
gene id: 1166018:FAES_RS01610
uniprot id: I0K2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1166018:FAES RS16565
gene id: 1166018:FAES_RS16565
uniprot id: I0KAY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1166018:FAES RS25500
gene id: 1166018:FAES_RS25500
uniprot id: I0KFT5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1166018:FAES RS11325
gene id: 1166018:FAES_RS11325
uniprot id: I0K7Z6
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1166018:FAES RS16420
gene id: 1166018:FAES_RS16420
uniprot id: I0KAW1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS11945
gene id: 1166018:FAES_RS11945
uniprot id: I0K8B4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS00730
gene id: 1166018:FAES_RS00730
uniprot id: I0K208
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS04100
gene id: 1166018:FAES_RS04100
uniprot id: I0K3Y1
names: Similarity
messages: Belongs to the TrpF family.

1166018:FAES RS01660
gene id: 1166018:FAES_RS01660
uniprot id: I0K2J1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS04300
gene id: 1166018:FAES_RS04300
uniprot id: I0K422
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1166018:FAES RS24155
gene id: 1166018:FAES_RS24155
uniprot id: I0KF21
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1166018:FAES RS02125
gene id: 1166018:FAES_RS02125
uniprot id: I0K2T8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS13140
gene id: 1166018:FAES_RS13140
uniprot id: I0K904
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1166018:FAES RS01555
gene id: 1166018:FAES_RS01555
uniprot id: I0K2G9
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

1166018:FAES RS06495
gene id: 1166018:FAES_RS06495
uniprot id: I0K5A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1166018:FAES RS02915
gene id: 1166018:FAES_RS02915
uniprot id: I0K395
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS05045
gene id: 1166018:FAES_RS05045
uniprot id: I0K4G6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1166018:FAES RS19765
gene id: 1166018:FAES_RS19765
uniprot id: I0KCN9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS25875
gene id: 1166018:FAES_RS25875
uniprot id: I0KG09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1166018:FAES RS24515
gene id: 1166018:FAES_RS24515
uniprot id: I0KF93
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1166018:FAES RS27125
gene id: 1166018:FAES_RS27125
uniprot id: I0KGQ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1166018:FAES RS25190
gene id: 1166018:FAES_RS25190
uniprot id: I0KFM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS05180
gene id: 1166018:FAES_RS05180
uniprot id: I0K4J4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1166018:FAES RS27080
gene id: 1166018:FAES_RS27080
uniprot id: I0KGP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1166018:FAES RS19575
gene id: 1166018:FAES_RS19575
uniprot id: I0KCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS00240
gene id: 1166018:FAES_RS00240
uniprot id: I0K1Q9
names: Similarity
messages: Belongs to the group II decarboxylase family.

1166018:FAES RS00665
gene id: 1166018:FAES_RS00665
uniprot id: I0K1Z3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS11280
gene id: 1166018:FAES_RS11280
uniprot id: I0K7Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1166018:FAES RS04995
gene id: 1166018:FAES_RS04995
uniprot id: I0K4F6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1166018:FAES RS22345
gene id: 1166018:FAES_RS22345
uniprot id: I0KE07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1166018:FAES RS27390
gene id: 1166018:FAES_RS27390
uniprot id: I0KGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1166018:FAES RS01935
gene id: 1166018:FAES_RS01935
uniprot id: I0K2P9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1166018:FAES RS14900
gene id: 1166018:FAES_RS14900
uniprot id: I0KA11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1166018:FAES RS12825
gene id: 1166018:FAES_RS12825
uniprot id: I0K8U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1166018:FAES RS04930
gene id: 1166018:FAES_RS04930
uniprot id: I0K4E7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1166018:FAES RS04650
gene id: 1166018:FAES_RS04650
uniprot id: I0K491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1166018:FAES RS04545
gene id: 1166018:FAES_RS04545
uniprot id: I0K472
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1166018:FAES RS11115
gene id: 1166018:FAES_RS11115
uniprot id: I0K7V2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS10830
gene id: 1166018:FAES_RS10830
uniprot id: I0K7Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1166018:FAES RS25475
gene id: 1166018:FAES_RS25475
uniprot id: I0KFT2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1166018:FAES RS18820
gene id: 1166018:FAES_RS18820
uniprot id: I0KC59
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1166018:FAES RS25950
gene id: 1166018:FAES_RS25950
uniprot id: I0KG23
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1166018:FAES RS21130
gene id: 1166018:FAES_RS21130
uniprot id: I0KDB8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1166018:FAES RS13020
gene id: 1166018:FAES_RS13020
uniprot id: I0K8Y1
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS18850
gene id: 1166018:FAES_RS18850
uniprot id: I0KC66
names: Cofactor
messages: Binds 2 iron ions per subunit.

1166018:FAES RS05460
gene id: 1166018:FAES_RS05460
uniprot id: I0K4P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1166018:FAES RS08025
gene id: 1166018:FAES_RS08025
uniprot id: I0K655
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1166018:FAES RS24300
gene id: 1166018:FAES_RS24300
uniprot id: I0KF50
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS23900
gene id: 1166018:FAES_RS23900
uniprot id: I0KEX0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1166018:FAES RS01245
gene id: 1166018:FAES_RS01245
uniprot id: I0K2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1166018:FAES RS11210
gene id: 1166018:FAES_RS11210
uniprot id: I0K7X2
names: Subcellular Location Annotation
messages: Cell inner membrane

1166018:FAES RS13760
gene id: 1166018:FAES_RS13760
uniprot id: I0K9D0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1166018:FAES RS10820
gene id: 1166018:FAES_RS10820
uniprot id: I0K7P8
names: Similarity
messages: Belongs to the sigma-54 factor family.

1166018:FAES RS18040
gene id: 1166018:FAES_RS18040
uniprot id: I0KBR6
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS24550
gene id: 1166018:FAES_RS24550
uniprot id: I0KFA0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS15290
gene id: 1166018:FAES_RS15290
uniprot id: I0KA87
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1166018:FAES RS12440
gene id: 1166018:FAES_RS12440
uniprot id: I0K8L2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS04540
gene id: 1166018:FAES_RS04540
uniprot id: I0K471
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS09500
gene id: 1166018:FAES_RS09500
uniprot id: I0K6Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1166018:FAES RS01065
gene id: 1166018:FAES_RS01065
uniprot id: I0K274
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS00790
gene id: 1166018:FAES_RS00790
uniprot id: I0K218
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS14910
gene id: 1166018:FAES_RS14910
uniprot id: I0KA13
names: Similarity
messages: Belongs to the ParB family.

1166018:FAES RS09830
gene id: 1166018:FAES_RS09830
uniprot id: I0K749
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS23170
gene id: 1166018:FAES_RS23170
uniprot id: I0KEH3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS08245
gene id: 1166018:FAES_RS08245
uniprot id: I0K697
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1166018:FAES RS06125
gene id: 1166018:FAES_RS06125
uniprot id: I0K529
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1166018:FAES RS24490
gene id: 1166018:FAES_RS24490
uniprot id: I0KF88
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1166018:FAES RS01250
gene id: 1166018:FAES_RS01250
uniprot id: I0K2A8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS18190
gene id: 1166018:FAES_RS18190
uniprot id: I0KBU7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1166018:FAES RS27250
gene id: 1166018:FAES_RS27250
uniprot id: I0KGT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1166018:FAES RS13105
gene id: 1166018:FAES_RS13105
uniprot id: I0K8Z7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS24950
gene id: 1166018:FAES_RS24950
uniprot id: I0KFH8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1166018:FAES RS04420
gene id: 1166018:FAES_RS04420
uniprot id: I0K447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS20780
gene id: 1166018:FAES_RS20780
uniprot id: I0KD47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1166018:FAES RS28410
gene id: 1166018:FAES_RS28410
uniprot id: I0KHG0
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

1166018:FAES RS04700
gene id: 1166018:FAES_RS04700
uniprot id: I0K4A1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS21915
gene id: 1166018:FAES_RS21915
uniprot id: I0KDS1
names: Similarity
messages: Belongs to the thioredoxin family.

1166018:FAES RS15770
gene id: 1166018:FAES_RS15770
uniprot id: I0KAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1166018:FAES RS28080
gene id: 1166018:FAES_RS28080
uniprot id: I0KH92
names: Similarity
messages: Belongs to the catalase family.

1166018:FAES RS00215
gene id: 1166018:FAES_RS00215
uniprot id: I0K1Q3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1166018:FAES RS25835
gene id: 1166018:FAES_RS25835
uniprot id: I0KG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS01430
gene id: 1166018:FAES_RS01430
uniprot id: I0K2E4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1166018:FAES RS28730
gene id: 1166018:FAES_RS28730
uniprot id: I0KHM5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS26395
gene id: 1166018:FAES_RS26395
uniprot id: I0KGA8
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1166018:FAES RS05650
gene id: 1166018:FAES_RS05650
uniprot id: I0K4T3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1166018:FAES RS16920
gene id: 1166018:FAES_RS16920
uniprot id: I0KB55
names: Similarity
messages: Belongs to the glutamate synthase family.

1166018:FAES RS21065
gene id: 1166018:FAES_RS21065
uniprot id: I0KDA5
names: Similarity
messages: Belongs to the WrbA family.

1166018:FAES RS21675
gene id: 1166018:FAES_RS21675
uniprot id: I0KDM3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS03920
gene id: 1166018:FAES_RS03920
uniprot id: I0K3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1166018:FAES RS25075
gene id: 1166018:FAES_RS25075
uniprot id: I0KFK3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1166018:FAES RS22335
gene id: 1166018:FAES_RS22335
uniprot id: I0KE05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1166018:FAES RS04105
gene id: 1166018:FAES_RS04105
uniprot id: I0K3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1166018:FAES RS00230
gene id: 1166018:FAES_RS00230
uniprot id: I0K1Q7
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

1166018:FAES RS07960
gene id: 1166018:FAES_RS07960
uniprot id: I0K642
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS01415
gene id: 1166018:FAES_RS01415
uniprot id: I0K2E1
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1166018:FAES RS15575
gene id: 1166018:FAES_RS15575
uniprot id: I0KAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS28060
gene id: 1166018:FAES_RS28060
uniprot id: I0KH90
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS12390
gene id: 1166018:FAES_RS12390
uniprot id: I0K8K2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS24625
gene id: 1166018:FAES_RS24625
uniprot id: I0KFB5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1166018:FAES RS22975
gene id: 1166018:FAES_RS22975
uniprot id: I0KED3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1166018:FAES RS01040
gene id: 1166018:FAES_RS01040
uniprot id: I0K269
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS26015
gene id: 1166018:FAES_RS26015
uniprot id: I0KG31
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS15265
gene id: 1166018:FAES_RS15265
uniprot id: I0KA83
names: Similarity
messages: Belongs to the peptidase M4 family.

1166018:FAES RS02925
gene id: 1166018:FAES_RS02925
uniprot id: I0K397
names: Similarity
messages: Belongs to the DtxR/MntR family.

1166018:FAES RS04275
gene id: 1166018:FAES_RS04275
uniprot id: I0K415
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS21335
gene id: 1166018:FAES_RS21335
uniprot id: I0KDF7
names: Function
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1166018:FAES RS04715
gene id: 1166018:FAES_RS04715
uniprot id: I0K4A4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1166018:FAES RS00100
gene id: 1166018:FAES_RS00100
uniprot id: I0K1N1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS17995
gene id: 1166018:FAES_RS17995
uniprot id: I0KBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1166018:FAES RS28740
gene id: 1166018:FAES_RS28740
uniprot id: I0KHM7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS27835
gene id: 1166018:FAES_RS27835
uniprot id: I0KH48
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1166018:FAES RS06565
gene id: 1166018:FAES_RS06565
uniprot id: I0K5B6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS15720
gene id: 1166018:FAES_RS15720
uniprot id: I0KAH3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1166018:FAES RS27155
gene id: 1166018:FAES_RS27155
uniprot id: I0KGR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1166018:FAES RS26540
gene id: 1166018:FAES_RS26540
uniprot id: I0KGD8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

1166018:FAES RS01565
gene id: 1166018:FAES_RS01565
uniprot id: I0K2H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1166018:FAES RS00340
gene id: 1166018:FAES_RS00340
uniprot id: I0K1S9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS12995
gene id: 1166018:FAES_RS12995
uniprot id: I0K8X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1166018:FAES RS23300
gene id: 1166018:FAES_RS23300
uniprot id: I0KEJ7
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS26790
gene id: 1166018:FAES_RS26790
uniprot id: I0KGJ0
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS03375
gene id: 1166018:FAES_RS03375
uniprot id: I0K3I6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1166018:FAES RS21290
gene id: 1166018:FAES_RS21290
uniprot id: I0KDE8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1166018:FAES RS03845
gene id: 1166018:FAES_RS03845
uniprot id: I0K3T1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1166018:FAES RS00415
gene id: 1166018:FAES_RS00415
uniprot id: I0K1U3
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1166018:FAES RS04430
gene id: 1166018:FAES_RS04430
uniprot id: I0K449
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1166018:FAES RS01580
gene id: 1166018:FAES_RS01580
uniprot id: I0K2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS24900
gene id: 1166018:FAES_RS24900
uniprot id: I0KFG9
names: Similarity
messages: Belongs to the peptidase M1 family.

1166018:FAES RS17820
gene id: 1166018:FAES_RS17820
uniprot id: I0KBM4
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1166018:FAES RS03360
gene id: 1166018:FAES_RS03360
uniprot id: I0K3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1166018:FAES RS04450
gene id: 1166018:FAES_RS04450
uniprot id: I0K453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1166018:FAES RS15955
gene id: 1166018:FAES_RS15955
uniprot id: I0KAM1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1166018:FAES RS12745
gene id: 1166018:FAES_RS12745
uniprot id: I0K8S6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS23055
gene id: 1166018:FAES_RS23055
uniprot id: I0KEF0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS13525
gene id: 1166018:FAES_RS13525
uniprot id: I0K981
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS03980
gene id: 1166018:FAES_RS03980
uniprot id: I0K3V7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1166018:FAES RS21170
gene id: 1166018:FAES_RS21170
uniprot id: I0KDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS21045
gene id: 1166018:FAES_RS21045
uniprot id: I0KDA1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS12350
gene id: 1166018:FAES_RS12350
uniprot id: I0K8J4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS10335
gene id: 1166018:FAES_RS10335
uniprot id: I0K7F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1166018:FAES RS03850
gene id: 1166018:FAES_RS03850
uniprot id: I0K3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS01095
gene id: 1166018:FAES_RS01095
uniprot id: I0K280
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS09035
gene id: 1166018:FAES_RS09035
uniprot id: I0K6P9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1166018:FAES RS03250
gene id: 1166018:FAES_RS03250
uniprot id: I0K3G1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1166018:FAES RS02985
gene id: 1166018:FAES_RS02985
uniprot id: I0K3A9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1166018:FAES RS05525
gene id: 1166018:FAES_RS05525
uniprot id: I0K4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1166018:FAES RS23680
gene id: 1166018:FAES_RS23680
uniprot id: I0KES4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS07470
gene id: 1166018:FAES_RS07470
uniprot id: I0K5U3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1166018:FAES RS23370
gene id: 1166018:FAES_RS23370
uniprot id: I0KEL0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1166018:FAES RS25080
gene id: 1166018:FAES_RS25080
uniprot id: I0KFK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1166018:FAES RS27225
gene id: 1166018:FAES_RS27225
uniprot id: I0KGS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1166018:FAES RS07145
gene id: 1166018:FAES_RS07145
uniprot id: I0K5M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1166018:FAES RS13945
gene id: 1166018:FAES_RS13945
uniprot id: I0K9G5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1166018:FAES RS02425
gene id: 1166018:FAES_RS02425
uniprot id: I0K2Z4
names: Similarity
messages: Belongs to the FPG family.

1166018:FAES RS27385
gene id: 1166018:FAES_RS27385
uniprot id: I0KGW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1166018:FAES RS21955
gene id: 1166018:FAES_RS21955
uniprot id: I0KDS9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS13775
gene id: 1166018:FAES_RS13775
uniprot id: I0K9D3
names: Subcellular Location Annotation
messages: Virion

1166018:FAES RS16710
gene id: 1166018:FAES_RS16710
uniprot id: I0KB11
names: Subunit
messages: Homodimer.

1166018:FAES RS28425
gene id: 1166018:FAES_RS28425
uniprot id: I0KHG4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1166018:FAES RS13680
gene id: 1166018:FAES_RS13680
uniprot id: I0K9B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1166018:FAES RS07130
gene id: 1166018:FAES_RS07130
uniprot id: I0K5M6
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS01070
gene id: 1166018:FAES_RS01070
uniprot id: I0K275
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS03440
gene id: 1166018:FAES_RS03440
uniprot id: I0K3J8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1166018:FAES RS21925
gene id: 1166018:FAES_RS21925
uniprot id: I0KDS3
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1166018:FAES RS13860
gene id: 1166018:FAES_RS13860
uniprot id: I0K9E9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1166018:FAES RS05705
gene id: 1166018:FAES_RS05705
uniprot id: I0K4U4
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS12585
gene id: 1166018:FAES_RS12585
uniprot id: I0K8P4
names: Similarity
messages: Belongs to the peptidase S41A family.

1166018:FAES RS09535
gene id: 1166018:FAES_RS09535
uniprot id: I0K6Z0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS12260
gene id: 1166018:FAES_RS12260
uniprot id: I0K8H7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1166018:FAES RS22540
gene id: 1166018:FAES_RS22540
uniprot id: I0KE44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1166018:FAES RS01570
gene id: 1166018:FAES_RS01570
uniprot id: I0K2H2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1166018:FAES RS10570
gene id: 1166018:FAES_RS10570
uniprot id: I0K7J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1166018:FAES RS25990
gene id: 1166018:FAES_RS25990
uniprot id: I0KG26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS27680
gene id: 1166018:FAES_RS27680
uniprot id: I0KH19
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS24775
gene id: 1166018:FAES_RS24775
uniprot id: I0KFE5
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS08360
gene id: 1166018:FAES_RS08360
uniprot id: I0K6B8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1166018:FAES RS22905
gene id: 1166018:FAES_RS22905
uniprot id: I0KEC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS22185
gene id: 1166018:FAES_RS22185
uniprot id: I0KDX5
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS22745
gene id: 1166018:FAES_RS22745
uniprot id: I0KE85
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1166018:FAES RS27395
gene id: 1166018:FAES_RS27395
uniprot id: I0KGW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1166018:FAES RS26855
gene id: 1166018:FAES_RS26855
uniprot id: I0KGK4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1166018:FAES RS11305
gene id: 1166018:FAES_RS11305
uniprot id: I0K7Z2
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1166018:FAES RS14630
gene id: 1166018:FAES_RS14630
uniprot id: I0K9V8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1166018:FAES RS26845
gene id: 1166018:FAES_RS26845
uniprot id: I0KGK2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1166018:FAES RS13355
gene id: 1166018:FAES_RS13355
uniprot id: I0K947
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1166018:FAES RS06550
gene id: 1166018:FAES_RS06550
uniprot id: I0K5B3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS06010
gene id: 1166018:FAES_RS06010
uniprot id: I0K506
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1166018:FAES RS00755
gene id: 1166018:FAES_RS00755
uniprot id: I0K214
names: Similarity
messages: Belongs to the AHA1 family.

1166018:FAES RS22550
gene id: 1166018:FAES_RS22550
uniprot id: I0KE46
names: Subcellular Location Annotation
messages: Periplasm

1166018:FAES RS10945
gene id: 1166018:FAES_RS10945
uniprot id: I0K7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1166018:FAES RS06255
gene id: 1166018:FAES_RS06255
uniprot id: I0K555
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS06525
gene id: 1166018:FAES_RS06525
uniprot id: I0K5A8
names: Similarity
messages: Belongs to the peptidase S41A family.

1166018:FAES RS01020
gene id: 1166018:FAES_RS01020
uniprot id: I0K265
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS03815
gene id: 1166018:FAES_RS03815
uniprot id: I0K3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1166018:FAES RS21340
gene id: 1166018:FAES_RS21340
uniprot id: I0KDF8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1166018:FAES RS13050
gene id: 1166018:FAES_RS13050
uniprot id: I0K8Y7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1166018:FAES RS11775
gene id: 1166018:FAES_RS11775
uniprot id: I0K880
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS01385
gene id: 1166018:FAES_RS01385
uniprot id: I0K2D6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1166018:FAES RS02455
gene id: 1166018:FAES_RS02455
uniprot id: I0K300
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1166018:FAES RS07805
gene id: 1166018:FAES_RS07805
uniprot id: I0K610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1166018:FAES RS07175
gene id: 1166018:FAES_RS07175
uniprot id: I0K5N5
names: Similarity
messages: Belongs to the UPF0758 family.

1166018:FAES RS04670
gene id: 1166018:FAES_RS04670
uniprot id: I0K495
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1166018:FAES RS00680
gene id: 1166018:FAES_RS00680
uniprot id: I0K1Z6
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

1166018:FAES RS27330
gene id: 1166018:FAES_RS27330
uniprot id: I0KGV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1166018:FAES RS07920
gene id: 1166018:FAES_RS07920
uniprot id: I0K634
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1166018:FAES RS05140
gene id: 1166018:FAES_RS05140
uniprot id: I0K4I5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1166018:FAES RS02570
gene id: 1166018:FAES_RS02570
uniprot id: I0K323
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1166018:FAES RS20100
gene id: 1166018:FAES_RS20100
uniprot id: I0KCV0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1166018:FAES RS18770
gene id: 1166018:FAES_RS18770
uniprot id: I0KC50
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS01485
gene id: 1166018:FAES_RS01485
uniprot id: I0K2F5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS18705
gene id: 1166018:FAES_RS18705
uniprot id: I0KC40
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1166018:FAES RS16940
gene id: 1166018:FAES_RS16940
uniprot id: I0KB59
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1166018:FAES RS15180
gene id: 1166018:FAES_RS15180
uniprot id: I0KA65
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1166018:FAES RS26550
gene id: 1166018:FAES_RS26550
uniprot id: I0KGE0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1166018:FAES RS01190
gene id: 1166018:FAES_RS01190
uniprot id: I0K297
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1166018:FAES RS02430
gene id: 1166018:FAES_RS02430
uniprot id: I0K2Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1166018:FAES RS23695
gene id: 1166018:FAES_RS23695
uniprot id: I0KES7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS28835
gene id: 1166018:FAES_RS28835
uniprot id: I0K3J4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1166018:FAES RS10855
gene id: 1166018:FAES_RS10855
uniprot id: I0K7Q6
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1166018:FAES RS11155
gene id: 1166018:FAES_RS11155
uniprot id: I0K7W1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS02920
gene id: 1166018:FAES_RS02920
uniprot id: I0K396
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1166018:FAES RS22250
gene id: 1166018:FAES_RS22250
uniprot id: I0KDY8
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS25605
gene id: 1166018:FAES_RS25605
uniprot id: I0KFV5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS07135
gene id: 1166018:FAES_RS07135
uniprot id: I0K5M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS03910
gene id: 1166018:FAES_RS03910
uniprot id: I0K3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1166018:FAES RS26115
gene id: 1166018:FAES_RS26115
uniprot id: I0KG50
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS04895
gene id: 1166018:FAES_RS04895
uniprot id: I0K4E0
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS10810
gene id: 1166018:FAES_RS10810
uniprot id: I0K7P6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1166018:FAES RS04305
gene id: 1166018:FAES_RS04305
uniprot id: I0K423
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS24845
gene id: 1166018:FAES_RS24845
uniprot id: I0KFF9
names: Similarity
messages: Belongs to the peptidase U62 family.

1166018:FAES RS05250
gene id: 1166018:FAES_RS05250
uniprot id: I0K4K8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS23635
gene id: 1166018:FAES_RS23635
uniprot id: I0KER4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1166018:FAES RS04515
gene id: 1166018:FAES_RS04515
uniprot id: I0K466
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1166018:FAES RS23025
gene id: 1166018:FAES_RS23025
uniprot id: I0KEE4
names: Similarity
messages: Belongs to the Nth/MutY family.

1166018:FAES RS04845
gene id: 1166018:FAES_RS04845
uniprot id: I0K4D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1166018:FAES RS24815
gene id: 1166018:FAES_RS24815
uniprot id: I0KFF3
names: Similarity
messages: Belongs to the peptidase U62 family.

1166018:FAES RS01175
gene id: 1166018:FAES_RS01175
uniprot id: I0K294
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS19515
gene id: 1166018:FAES_RS19515
uniprot id: I0KCJ0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1166018:FAES RS06450
gene id: 1166018:FAES_RS06450
uniprot id: I0K593
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS14275
gene id: 1166018:FAES_RS14275
uniprot id: I0K9N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1166018:FAES RS02145
gene id: 1166018:FAES_RS02145
uniprot id: I0K2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1166018:FAES RS06265
gene id: 1166018:FAES_RS06265
uniprot id: I0K556
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1166018:FAES RS06620
gene id: 1166018:FAES_RS06620
uniprot id: I0K5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1166018:FAES RS14495
gene id: 1166018:FAES_RS14495
uniprot id: I0K9T1
names: Similarity
messages: Belongs to the peptidase S49 family.

1166018:FAES RS03355
gene id: 1166018:FAES_RS03355
uniprot id: I0K3I2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS23415
gene id: 1166018:FAES_RS23415
uniprot id: I0KEL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1166018:FAES RS13005
gene id: 1166018:FAES_RS13005
uniprot id: I0K8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1166018:FAES RS24695
gene id: 1166018:FAES_RS24695
uniprot id: I0KFC9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1166018:FAES RS23915
gene id: 1166018:FAES_RS23915
uniprot id: I0KEX4
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS26505
gene id: 1166018:FAES_RS26505
uniprot id: I0KGD1
names: Similarity
messages: Belongs to the peptidase M16 family.

1166018:FAES RS09435
gene id: 1166018:FAES_RS09435
uniprot id: I0K6X0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1166018:FAES RS15630
gene id: 1166018:FAES_RS15630
uniprot id: I0KAF4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1166018:FAES RS13665
gene id: 1166018:FAES_RS13665
uniprot id: I0K9B1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS05295
gene id: 1166018:FAES_RS05295
uniprot id: I0K4L7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1166018:FAES RS25460
gene id: 1166018:FAES_RS25460
uniprot id: I0KFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1166018:FAES RS07160
gene id: 1166018:FAES_RS07160
uniprot id: I0K5N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1166018:FAES RS27115
gene id: 1166018:FAES_RS27115
uniprot id: I0KGQ6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1166018:FAES RS17180
gene id: 1166018:FAES_RS17180
uniprot id: I0KB98
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS17460
gene id: 1166018:FAES_RS17460
uniprot id: I0KBF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1166018:FAES RS06005
gene id: 1166018:FAES_RS06005
uniprot id: I0K505
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1166018:FAES RS06585
gene id: 1166018:FAES_RS06585
uniprot id: I0K5C0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1166018:FAES RS00815
gene id: 1166018:FAES_RS00815
uniprot id: I0K223
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS07930
gene id: 1166018:FAES_RS07930
uniprot id: I0K636
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1166018:FAES RS19655
gene id: 1166018:FAES_RS19655
uniprot id: I0KCL8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1166018:FAES RS26880
gene id: 1166018:FAES_RS26880
uniprot id: I0KGK9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS19825
gene id: 1166018:FAES_RS19825
uniprot id: I0KCQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1166018:FAES RS05395
gene id: 1166018:FAES_RS05395
uniprot id: I0K4N7
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS23435
gene id: 1166018:FAES_RS23435
uniprot id: I0KEM3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS04725
gene id: 1166018:FAES_RS04725
uniprot id: I0K4A6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1166018:FAES RS01730
gene id: 1166018:FAES_RS01730
uniprot id: I0K2K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1166018:FAES RS05905
gene id: 1166018:FAES_RS05905
uniprot id: I0K4Y5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1166018:FAES RS10545
gene id: 1166018:FAES_RS10545
uniprot id: I0K7J4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1166018:FAES RS14570
gene id: 1166018:FAES_RS14570
uniprot id: I0K9U6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1166018:FAES RS15755
gene id: 1166018:FAES_RS15755
uniprot id: I0KAI0
names: Subcellular Location Annotation
messages: Nucleus

1166018:FAES RS12075
gene id: 1166018:FAES_RS12075
uniprot id: I0K8E1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1166018:FAES RS00040
gene id: 1166018:FAES_RS00040
uniprot id: I0K1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1166018:FAES RS05370
gene id: 1166018:FAES_RS05370
uniprot id: I0K4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1166018:FAES RS29825
gene id: 1166018:FAES_RS29825
uniprot id: I0KGR2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1166018:FAES RS06965
gene id: 1166018:FAES_RS06965
uniprot id: I0K5J4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1166018:FAES RS01560
gene id: 1166018:FAES_RS01560
uniprot id: I0K2H0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1166018:FAES RS06165
gene id: 1166018:FAES_RS06165
uniprot id: I0K537
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS02380
gene id: 1166018:FAES_RS02380
uniprot id: I0K2Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1166018:FAES RS08000
gene id: 1166018:FAES_RS08000
uniprot id: I0K650
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1166018:FAES RS27045
gene id: 1166018:FAES_RS27045
uniprot id: I0KGP2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS18625
gene id: 1166018:FAES_RS18625
uniprot id: I0KC26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1166018:FAES RS21295
gene id: 1166018:FAES_RS21295
uniprot id: I0KDE9
names: Similarity
messages: Belongs to the ribF family.

1166018:FAES RS04365
gene id: 1166018:FAES_RS04365
uniprot id: I0K436
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1166018:FAES RS26145
gene id: 1166018:FAES_RS26145
uniprot id: I0KG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1166018:FAES RS05375
gene id: 1166018:FAES_RS05375
uniprot id: I0K4N3
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS13350
gene id: 1166018:FAES_RS13350
uniprot id: I0K946
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1166018:FAES RS03210
gene id: 1166018:FAES_RS03210
uniprot id: I0K3F3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1166018:FAES RS23020
gene id: 1166018:FAES_RS23020
uniprot id: I0KEE3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1166018:FAES RS27170
gene id: 1166018:FAES_RS27170
uniprot id: I0KGR8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1166018:FAES RS05585
gene id: 1166018:FAES_RS05585
uniprot id: I0K4S0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS24825
gene id: 1166018:FAES_RS24825
uniprot id: I0KFF5
names: Similarity
messages: Belongs to the peptidase U62 family.

1166018:FAES RS09015
gene id: 1166018:FAES_RS09015
uniprot id: I0K6P5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1166018:FAES RS09565
gene id: 1166018:FAES_RS09565
uniprot id: I0K6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

1166018:FAES RS05965
gene id: 1166018:FAES_RS05965
uniprot id: I0K4Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS17240
gene id: 1166018:FAES_RS17240
uniprot id: I0KBB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1166018:FAES RS22930
gene id: 1166018:FAES_RS22930
uniprot id: I0KEC5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS22610
gene id: 1166018:FAES_RS22610
uniprot id: I0KE59
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS26010
gene id: 1166018:FAES_RS26010
uniprot id: I0KG30
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS24605
gene id: 1166018:FAES_RS24605
uniprot id: I0KFB1
names: Similarity
messages: Belongs to the nitroreductase family.

1166018:FAES RS18300
gene id: 1166018:FAES_RS18300
uniprot id: I0KBW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1166018:FAES RS27305
gene id: 1166018:FAES_RS27305
uniprot id: I0KGU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1166018:FAES RS25930
gene id: 1166018:FAES_RS25930
uniprot id: I0KG20
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1166018:FAES RS16905
gene id: 1166018:FAES_RS16905
uniprot id: I0KB52
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS24150
gene id: 1166018:FAES_RS24150
uniprot id: I0KF20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS13270
gene id: 1166018:FAES_RS13270
uniprot id: I0K930
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1166018:FAES RS04590
gene id: 1166018:FAES_RS04590
uniprot id: I0K481
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1166018:FAES RS02800
gene id: 1166018:FAES_RS02800
uniprot id: I0K372
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1166018:FAES RS08300
gene id: 1166018:FAES_RS08300
uniprot id: I0K6A6
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS24025
gene id: 1166018:FAES_RS24025
uniprot id: I0KEZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
messages: Monomer.
messages: Periplasm

1166018:FAES RS20935
gene id: 1166018:FAES_RS20935
uniprot id: I0KD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1166018:FAES RS12205
gene id: 1166018:FAES_RS12205
uniprot id: I0K8G7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS14960
gene id: 1166018:FAES_RS14960
uniprot id: I0KA23
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS21855
gene id: 1166018:FAES_RS21855
uniprot id: I0KDQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1166018:FAES RS06930
gene id: 1166018:FAES_RS06930
uniprot id: I0K5I7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1166018:FAES RS01460
gene id: 1166018:FAES_RS01460
uniprot id: I0K2E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1166018:FAES RS06215
gene id: 1166018:FAES_RS06215
uniprot id: I0K547
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1166018:FAES RS14520
gene id: 1166018:FAES_RS14520
uniprot id: I0K9T6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1166018:FAES RS03380
gene id: 1166018:FAES_RS03380
uniprot id: I0K3I7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1166018:FAES RS26005
gene id: 1166018:FAES_RS26005
uniprot id: I0KG29
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1166018:FAES RS10885
gene id: 1166018:FAES_RS10885
uniprot id: I0K7R2
names: Similarity
messages: Belongs to the peptidase S33 family.

1166018:FAES RS00480
gene id: 1166018:FAES_RS00480
uniprot id: I0K1V6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS27795
gene id: 1166018:FAES_RS27795
uniprot id: I0KH40
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1166018:FAES RS15475
gene id: 1166018:FAES_RS15475
uniprot id: I0KAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1166018:FAES RS12595
gene id: 1166018:FAES_RS12595
uniprot id: I0K8P6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1166018:FAES RS07125
gene id: 1166018:FAES_RS07125
uniprot id: I0K5M5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1166018:FAES RS24640
gene id: 1166018:FAES_RS24640
uniprot id: I0KFB8
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1166018:FAES RS24890
gene id: 1166018:FAES_RS24890
uniprot id: I0KFG7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1166018:FAES RS03395
gene id: 1166018:FAES_RS03395
uniprot id: I0K3J0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1166018:FAES RS26055
gene id: 1166018:FAES_RS26055
uniprot id: I0KG38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1166018:FAES RS03125
gene id: 1166018:FAES_RS03125
uniprot id: I0K3D6
names: Similarity
messages: Belongs to the CarB family.

1166018:FAES RS06875
gene id: 1166018:FAES_RS06875
uniprot id: I0K5H6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS26655
gene id: 1166018:FAES_RS26655
uniprot id: I0KGG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1166018:FAES RS00005
gene id: 1166018:FAES_RS00005
uniprot id: I0K1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1166018:FAES RS00750
gene id: 1166018:FAES_RS00750
uniprot id: I0K213
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS19740
gene id: 1166018:FAES_RS19740
uniprot id: I0KCN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1166018:FAES RS27255
gene id: 1166018:FAES_RS27255
uniprot id: I0KGT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1166018:FAES RS00160
gene id: 1166018:FAES_RS00160
uniprot id: I0K1P3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1166018:FAES RS03805
gene id: 1166018:FAES_RS03805
uniprot id: I0K3S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS29035
gene id: 1166018:FAES_RS29035
uniprot id: I0KA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1166018:FAES RS19170
gene id: 1166018:FAES_RS19170
uniprot id: I0KCC2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1166018:FAES RS21275
gene id: 1166018:FAES_RS21275
uniprot id: I0KDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1166018:FAES RS10975
gene id: 1166018:FAES_RS10975
uniprot id: I0K7S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1166018:FAES RS01060
gene id: 1166018:FAES_RS01060
uniprot id: I0K273
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS11165
gene id: 1166018:FAES_RS11165
uniprot id: I0K7W3
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS24485
gene id: 1166018:FAES_RS24485
uniprot id: I0KF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1166018:FAES RS17235
gene id: 1166018:FAES_RS17235
uniprot id: I0KBA9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS16935
gene id: 1166018:FAES_RS16935
uniprot id: I0KB58
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1166018:FAES RS03260
gene id: 1166018:FAES_RS03260
uniprot id: I0K3G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1166018:FAES RS16010
gene id: 1166018:FAES_RS16010
uniprot id: I0KAN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1166018:FAES RS21240
gene id: 1166018:FAES_RS21240
uniprot id: I0KDD8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1166018:FAES RS22865
gene id: 1166018:FAES_RS22865
uniprot id: I0KEB1
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS24635
gene id: 1166018:FAES_RS24635
uniprot id: I0KFB7
names: Similarity
messages: Belongs to the YicC/YloC family.

1166018:FAES RS00935
gene id: 1166018:FAES_RS00935
uniprot id: I0K248
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS04150
gene id: 1166018:FAES_RS04150
uniprot id: I0K3Z1
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1166018:FAES RS23355
gene id: 1166018:FAES_RS23355
uniprot id: I0KEK7
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS08990
gene id: 1166018:FAES_RS08990
uniprot id: I0K6P0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1166018:FAES RS06995
gene id: 1166018:FAES_RS06995
uniprot id: I0K5K0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS24090
gene id: 1166018:FAES_RS24090
uniprot id: I0KF08
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS26585
gene id: 1166018:FAES_RS26585
uniprot id: I0KGE9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1166018:FAES RS00710
gene id: 1166018:FAES_RS00710
uniprot id: I0K204
names: Similarity
messages: Belongs to the peptidase S33 family.

1166018:FAES RS09770
gene id: 1166018:FAES_RS09770
uniprot id: I0K737
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1166018:FAES RS09430
gene id: 1166018:FAES_RS09430
uniprot id: I0K6W9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS07980
gene id: 1166018:FAES_RS07980
uniprot id: I0K646
names: Similarity
messages: Belongs to the asparagine synthetase family.

1166018:FAES RS06530
gene id: 1166018:FAES_RS06530
uniprot id: I0K5A9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1166018:FAES RS12845
gene id: 1166018:FAES_RS12845
uniprot id: I0K8U5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1166018:FAES RS06900
gene id: 1166018:FAES_RS06900
uniprot id: I0K5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1166018:FAES RS08425
gene id: 1166018:FAES_RS08425
uniprot id: I0K6C6
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS22235
gene id: 1166018:FAES_RS22235
uniprot id: I0KDY5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS11785
gene id: 1166018:FAES_RS11785
uniprot id: I0K883
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1166018:FAES RS10340
gene id: 1166018:FAES_RS10340
uniprot id: I0K7F2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1166018:FAES RS05495
gene id: 1166018:FAES_RS05495
uniprot id: I0K4Q3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1166018:FAES RS22935
gene id: 1166018:FAES_RS22935
uniprot id: I0KEC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1166018:FAES RS10920
gene id: 1166018:FAES_RS10920
uniprot id: I0K7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS09505
gene id: 1166018:FAES_RS09505
uniprot id: I0K6Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS17815
gene id: 1166018:FAES_RS17815
uniprot id: I0KBM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1166018:FAES RS04975
gene id: 1166018:FAES_RS04975
uniprot id: I0K4F3
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1166018:FAES RS09780
gene id: 1166018:FAES_RS09780
uniprot id: I0K739
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1166018:FAES RS04875
gene id: 1166018:FAES_RS04875
uniprot id: I0K4D6
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS01360
gene id: 1166018:FAES_RS01360
uniprot id: I0K2D1
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1166018:FAES RS23895
gene id: 1166018:FAES_RS23895
uniprot id: I0KEW9
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1166018:FAES RS00955
gene id: 1166018:FAES_RS00955
uniprot id: I0K252
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS01380
gene id: 1166018:FAES_RS01380
uniprot id: I0K2D5
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS02775
gene id: 1166018:FAES_RS02775
uniprot id: I0K367
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS23870
gene id: 1166018:FAES_RS23870
uniprot id: I0KEW3
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS07605
gene id: 1166018:FAES_RS07605
uniprot id: I0K5W8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS17545
gene id: 1166018:FAES_RS17545
uniprot id: I0KBH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1166018:FAES RS27130
gene id: 1166018:FAES_RS27130
uniprot id: I0KGQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1166018:FAES RS06115
gene id: 1166018:FAES_RS06115
uniprot id: I0K527
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1166018:FAES RS06225
gene id: 1166018:FAES_RS06225
uniprot id: I0K549
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1166018:FAES RS01085
gene id: 1166018:FAES_RS01085
uniprot id: I0K278
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS15855
gene id: 1166018:FAES_RS15855
uniprot id: I0KAK2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1166018:FAES RS06180
gene id: 1166018:FAES_RS06180
uniprot id: I0K540
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1166018:FAES RS27910
gene id: 1166018:FAES_RS27910
uniprot id: I0KH63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1166018:FAES RS06895
gene id: 1166018:FAES_RS06895
uniprot id: I0K5I0
names: Similarity
messages: Belongs to the LEA type 2 family.

1166018:FAES RS07380
gene id: 1166018:FAES_RS07380
uniprot id: I0K5S4
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS01235
gene id: 1166018:FAES_RS01235
uniprot id: I0K2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS08070
gene id: 1166018:FAES_RS08070
uniprot id: I0K662
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1166018:FAES RS14220
gene id: 1166018:FAES_RS14220
uniprot id: I0K9M5
names: Similarity
messages: Belongs to the GroES chaperonin family.

1166018:FAES RS27775
gene id: 1166018:FAES_RS27775
uniprot id: I0KH36
names: Similarity
messages: Belongs to the LOG family.

1166018:FAES RS06370
gene id: 1166018:FAES_RS06370
uniprot id: I0K575
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

1166018:FAES RS08985
gene id: 1166018:FAES_RS08985
uniprot id: I0K6N9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1166018:FAES RS14345
gene id: 1166018:FAES_RS14345
uniprot id: I0K9Q1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1166018:FAES RS07905
gene id: 1166018:FAES_RS07905
uniprot id: I0K631
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1166018:FAES RS24505
gene id: 1166018:FAES_RS24505
uniprot id: I0KF91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1166018:FAES RS03885
gene id: 1166018:FAES_RS03885
uniprot id: I0K3T9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1166018:FAES RS21315
gene id: 1166018:FAES_RS21315
uniprot id: I0KDF3
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1166018:FAES RS14305
gene id: 1166018:FAES_RS14305
uniprot id: I0K9P4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS18215
gene id: 1166018:FAES_RS18215
uniprot id: I0KBV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1166018:FAES RS21405
gene id: 1166018:FAES_RS21405
uniprot id: I0KDG9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1166018:FAES RS12980
gene id: 1166018:FAES_RS12980
uniprot id: I0K8X3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1166018:FAES RS00975
gene id: 1166018:FAES_RS00975
uniprot id: I0K256
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1166018:FAES RS28685
gene id: 1166018:FAES_RS28685
uniprot id: I0KHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1166018:FAES RS08590
gene id: 1166018:FAES_RS08590
uniprot id: I0K6G2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS17830
gene id: 1166018:FAES_RS17830
uniprot id: I0KBM5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1166018:FAES RS04175
gene id: 1166018:FAES_RS04175
uniprot id: I0K3Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1166018:FAES RS23940
gene id: 1166018:FAES_RS23940
uniprot id: I0KEY0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS25365
gene id: 1166018:FAES_RS25365
uniprot id: I0KFR0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS00070
gene id: 1166018:FAES_RS00070
uniprot id: I0K1M5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1166018:FAES RS04425
gene id: 1166018:FAES_RS04425
uniprot id: I0K448
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS03085
gene id: 1166018:FAES_RS03085
uniprot id: I0K3C9
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1166018:FAES RS10560
gene id: 1166018:FAES_RS10560
uniprot id: I0K7J7
names: Similarity
messages: Belongs to the peptidase S13 family.

1166018:FAES RS22990
gene id: 1166018:FAES_RS22990
uniprot id: I0KED7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1166018:FAES RS24170
gene id: 1166018:FAES_RS24170
uniprot id: I0KF24
names: Similarity
messages: Belongs to the UPF0310 family.

1166018:FAES RS26740
gene id: 1166018:FAES_RS26740
uniprot id: I0KGI1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1166018:FAES RS03220
gene id: 1166018:FAES_RS03220
uniprot id: I0K3F5
names: Similarity
messages: Belongs to the sterol desaturase family.

1166018:FAES RS13620
gene id: 1166018:FAES_RS13620
uniprot id: I0K9A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1166018:FAES RS07165
gene id: 1166018:FAES_RS07165
uniprot id: I0K5N3
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS24190
gene id: 1166018:FAES_RS24190
uniprot id: I0KF29
names: Subunit
messages: Homodimer.

1166018:FAES RS07455
gene id: 1166018:FAES_RS07455
uniprot id: I0K5U0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1166018:FAES RS20810
gene id: 1166018:FAES_RS20810
uniprot id: I0KD52
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1166018:FAES RS12190
gene id: 1166018:FAES_RS12190
uniprot id: I0K8G4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS22160
gene id: 1166018:FAES_RS22160
uniprot id: I0KDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS24990
gene id: 1166018:FAES_RS24990
uniprot id: I0KFI6
names: Similarity
messages: Belongs to the peptidase C1 family.

1166018:FAES RS23095
gene id: 1166018:FAES_RS23095
uniprot id: I0KEF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1166018:FAES RS01515
gene id: 1166018:FAES_RS01515
uniprot id: I0K2G1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1166018:FAES RS00645
gene id: 1166018:FAES_RS00645
uniprot id: I0K1Y9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS21875
gene id: 1166018:FAES_RS21875
uniprot id: I0KDR2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1166018:FAES RS07870
gene id: 1166018:FAES_RS07870
uniprot id: I0K624
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS18880
gene id: 1166018:FAES_RS18880
uniprot id: I0KC72
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS15650
gene id: 1166018:FAES_RS15650
uniprot id: I0KAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1166018:FAES RS22245
gene id: 1166018:FAES_RS22245
uniprot id: I0KDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS08770
gene id: 1166018:FAES_RS08770
uniprot id: I0K6J5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1166018:FAES RS09010
gene id: 1166018:FAES_RS09010
uniprot id: I0K6P4
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1166018:FAES RS09695
gene id: 1166018:FAES_RS09695
uniprot id: I0K722
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS08980
gene id: 1166018:FAES_RS08980
uniprot id: I0K6N8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1166018:FAES RS17065
gene id: 1166018:FAES_RS17065
uniprot id: I0KB76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1166018:FAES RS15875
gene id: 1166018:FAES_RS15875
uniprot id: I0KAK5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1166018:FAES RS07370
gene id: 1166018:FAES_RS07370
uniprot id: I0K5S2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS27265
gene id: 1166018:FAES_RS27265
uniprot id: I0KGT7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1166018:FAES RS06065
gene id: 1166018:FAES_RS06065
uniprot id: I0K517
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1166018:FAES RS00670
gene id: 1166018:FAES_RS00670
uniprot id: I0K1Z4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS00390
gene id: 1166018:FAES_RS00390
uniprot id: I0K1T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1166018:FAES RS26460
gene id: 1166018:FAES_RS26460
uniprot id: I0KGC1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS14360
gene id: 1166018:FAES_RS14360
uniprot id: I0K9Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1166018:FAES RS25790
gene id: 1166018:FAES_RS25790
uniprot id: I0KFZ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS25265
gene id: 1166018:FAES_RS25265
uniprot id: I0KFN8
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS01170
gene id: 1166018:FAES_RS01170
uniprot id: I0K293
names: Similarity
messages: Belongs to the OprB family.

1166018:FAES RS04380
gene id: 1166018:FAES_RS04380
uniprot id: I0K439
names: Similarity
messages: Belongs to the manganese catalase family.

1166018:FAES RS18140
gene id: 1166018:FAES_RS18140
uniprot id: I0KBT7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS00860
gene id: 1166018:FAES_RS00860
uniprot id: I0K233
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS00400
gene id: 1166018:FAES_RS00400
uniprot id: I0K1U0
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS10125
gene id: 1166018:FAES_RS10125
uniprot id: I0K7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS05485
gene id: 1166018:FAES_RS05485
uniprot id: I0K4Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1166018:FAES RS24430
gene id: 1166018:FAES_RS24430
uniprot id: I0KF76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS27930
gene id: 1166018:FAES_RS27930
uniprot id: I0KH67
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1166018:FAES RS13900
gene id: 1166018:FAES_RS13900
uniprot id: I0K9F6
names: Similarity
messages: Belongs to the IlvD/Edd family.

1166018:FAES RS27790
gene id: 1166018:FAES_RS27790
uniprot id: I0KH39
names: Similarity
messages: Belongs to the oxoprolinase family.

1166018:FAES RS04550
gene id: 1166018:FAES_RS04550
uniprot id: I0K473
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1166018:FAES RS21145
gene id: 1166018:FAES_RS21145
uniprot id: I0KDC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1166018:FAES RS26830
gene id: 1166018:FAES_RS26830
uniprot id: I0KGJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1166018:FAES RS26285
gene id: 1166018:FAES_RS26285
uniprot id: I0KG86
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1166018:FAES RS08855
gene id: 1166018:FAES_RS08855
uniprot id: I0K6L2
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1166018:FAES RS27445
gene id: 1166018:FAES_RS27445
uniprot id: I0KGX5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1166018:FAES RS12405
gene id: 1166018:FAES_RS12405
uniprot id: I0K8K5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1166018:FAES RS13690
gene id: 1166018:FAES_RS13690
uniprot id: I0K9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1166018:FAES RS22820
gene id: 1166018:FAES_RS22820
uniprot id: I0KEA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1166018:FAES RS22960
gene id: 1166018:FAES_RS22960
uniprot id: I0KED0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1166018:FAES RS26100
gene id: 1166018:FAES_RS26100
uniprot id: I0KG47
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1166018:FAES RS15300
gene id: 1166018:FAES_RS15300
uniprot id: I0KA89
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS24340
gene id: 1166018:FAES_RS24340
uniprot id: I0KF58
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS11110
gene id: 1166018:FAES_RS11110
uniprot id: I0K7V1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1166018:FAES RS10930
gene id: 1166018:FAES_RS10930
uniprot id: I0K7S1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS27200
gene id: 1166018:FAES_RS27200
uniprot id: I0KGS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1166018:FAES RS06770
gene id: 1166018:FAES_RS06770
uniprot id: I0K5F9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1166018:FAES RS07925
gene id: 1166018:FAES_RS07925
uniprot id: I0K635
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS15890
gene id: 1166018:FAES_RS15890
uniprot id: I0KAK8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS26410
gene id: 1166018:FAES_RS26410
uniprot id: I0KGB1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS26400
gene id: 1166018:FAES_RS26400
uniprot id: I0KGA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1166018:FAES RS03035
gene id: 1166018:FAES_RS03035
uniprot id: I0K3B9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS06080
gene id: 1166018:FAES_RS06080
uniprot id: I0K520
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1166018:FAES RS09530
gene id: 1166018:FAES_RS09530
uniprot id: I0K6Y9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS10375
gene id: 1166018:FAES_RS10375
uniprot id: I0K7F9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS25320
gene id: 1166018:FAES_RS25320
uniprot id: I0KFQ1
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1166018:FAES RS03225
gene id: 1166018:FAES_RS03225
uniprot id: I0K3F6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1166018:FAES RS14835
gene id: 1166018:FAES_RS14835
uniprot id: I0K9Z7
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

1166018:FAES RS26270
gene id: 1166018:FAES_RS26270
uniprot id: I0KG82
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1166018:FAES RS23865
gene id: 1166018:FAES_RS23865
uniprot id: I0KEW2
names: Similarity
messages: Belongs to the YciI family.

1166018:FAES RS24325
gene id: 1166018:FAES_RS24325
uniprot id: I0KF55
names: Subcellular Location Annotation
messages: Cell inner membrane

1166018:FAES RS23550
gene id: 1166018:FAES_RS23550
uniprot id: I0KEP6
names: Similarity
messages: Belongs to the peptidase S66 family.

1166018:FAES RS00050
gene id: 1166018:FAES_RS00050
uniprot id: I0K1M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1166018:FAES RS21485
gene id: 1166018:FAES_RS21485
uniprot id: I0KDI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1166018:FAES RS24360
gene id: 1166018:FAES_RS24360
uniprot id: I0KF62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1166018:FAES RS27750
gene id: 1166018:FAES_RS27750
uniprot id: I0KH31
names: Similarity
messages: Belongs to the NAPRTase family.

1166018:FAES RS11920
gene id: 1166018:FAES_RS11920
uniprot id: I0K8A9
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS09545
gene id: 1166018:FAES_RS09545
uniprot id: I0K6Z2
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1166018:FAES RS27050
gene id: 1166018:FAES_RS27050
uniprot id: I0KGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1166018:FAES RS02375
gene id: 1166018:FAES_RS02375
uniprot id: I0K2Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1166018:FAES RS06405
gene id: 1166018:FAES_RS06405
uniprot id: I0K584
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS08970
gene id: 1166018:FAES_RS08970
uniprot id: I0K6N6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1166018:FAES RS09560
gene id: 1166018:FAES_RS09560
uniprot id: I0K6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1166018:FAES RS18075
gene id: 1166018:FAES_RS18075
uniprot id: I0KBS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1166018:FAES RS21310
gene id: 1166018:FAES_RS21310
uniprot id: I0KDF2
names: Similarity
messages: Belongs to the DSD1 family.

1166018:FAES RS06170
gene id: 1166018:FAES_RS06170
uniprot id: I0K538
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1166018:FAES RS10655
gene id: 1166018:FAES_RS10655
uniprot id: I0K7L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1166018:FAES RS19155
gene id: 1166018:FAES_RS19155
uniprot id: I0KCB8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1166018:FAES RS17155
gene id: 1166018:FAES_RS17155
uniprot id: I0KB93
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS22945
gene id: 1166018:FAES_RS22945
uniprot id: I0KEC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1166018:FAES RS17580
gene id: 1166018:FAES_RS17580
uniprot id: I0KBH8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS17565
gene id: 1166018:FAES_RS17565
uniprot id: I0KBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

1166018:FAES RS28200
gene id: 1166018:FAES_RS28200
uniprot id: I0KHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS11735
gene id: 1166018:FAES_RS11735
uniprot id: I0K873
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1166018:FAES RS13915
gene id: 1166018:FAES_RS13915
uniprot id: I0K9F9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS00355
gene id: 1166018:FAES_RS00355
uniprot id: I0K1T2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS28680
gene id: 1166018:FAES_RS28680
uniprot id: I0KHL5
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS05880
gene id: 1166018:FAES_RS05880
uniprot id: I0K4X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS06140
gene id: 1166018:FAES_RS06140
uniprot id: I0K532
names: Similarity
messages: Belongs to the UPF0102 family.

1166018:FAES RS27220
gene id: 1166018:FAES_RS27220
uniprot id: I0KGS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1166018:FAES RS18100
gene id: 1166018:FAES_RS18100
uniprot id: I0KBS9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS13225
gene id: 1166018:FAES_RS13225
uniprot id: I0K921
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS16725
gene id: 1166018:FAES_RS16725
uniprot id: I0KB14
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1166018:FAES RS12230
gene id: 1166018:FAES_RS12230
uniprot id: I0K8H2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS27655
gene id: 1166018:FAES_RS27655
uniprot id: I0KH14
names: Similarity
messages: Belongs to the fabD family.

1166018:FAES RS21230
gene id: 1166018:FAES_RS21230
uniprot id: I0KDD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1166018:FAES RS13980
gene id: 1166018:FAES_RS13980
uniprot id: I0K9H3
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1166018:FAES RS01545
gene id: 1166018:FAES_RS01545
uniprot id: I0K2G7
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

1166018:FAES RS03905
gene id: 1166018:FAES_RS03905
uniprot id: I0K3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1166018:FAES RS19235
gene id: 1166018:FAES_RS19235
uniprot id: I0KCD5
names: Similarity
messages: Belongs to the peptidase M16 family.

1166018:FAES RS06275
gene id: 1166018:FAES_RS06275
uniprot id: I0K558
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1166018:FAES RS22030
gene id: 1166018:FAES_RS22030
uniprot id: I0KDU4
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS04795
gene id: 1166018:FAES_RS04795
uniprot id: I0K4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1166018:FAES RS29090
gene id: 1166018:FAES_RS29090
uniprot id: I0KB42
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1166018:FAES RS00125
gene id: 1166018:FAES_RS00125
uniprot id: I0K1N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS19410
gene id: 1166018:FAES_RS19410
uniprot id: I0KCH0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS05450
gene id: 1166018:FAES_RS05450
uniprot id: I0K4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1166018:FAES RS22785
gene id: 1166018:FAES_RS22785
uniprot id: I0KE94
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1166018:FAES RS25335
gene id: 1166018:FAES_RS25335
uniprot id: I0KFQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1166018:FAES RS27485
gene id: 1166018:FAES_RS27485
uniprot id: I0KGY2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS27465
gene id: 1166018:FAES_RS27465
uniprot id: I0KGX9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1166018:FAES RS08840
gene id: 1166018:FAES_RS08840
uniprot id: I0K6K9
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1166018:FAES RS26450
gene id: 1166018:FAES_RS26450
uniprot id: I0KGB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1166018:FAES RS18645
gene id: 1166018:FAES_RS18645
uniprot id: I0KC30
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1166018:FAES RS15145
gene id: 1166018:FAES_RS15145
uniprot id: I0KA58
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1166018:FAES RS22095
gene id: 1166018:FAES_RS22095
uniprot id: I0KDV7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1166018:FAES RS10420
gene id: 1166018:FAES_RS10420
uniprot id: I0K7G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1166018:FAES RS14725
gene id: 1166018:FAES_RS14725
uniprot id: I0K9X6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1166018:FAES RS28750
gene id: 1166018:FAES_RS28750
uniprot id: I0KHM9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS28045
gene id: 1166018:FAES_RS28045
uniprot id: I0KH87
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1166018:FAES RS11830
gene id: 1166018:FAES_RS11830
uniprot id: I0K891
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1166018:FAES RS27165
gene id: 1166018:FAES_RS27165
uniprot id: I0KGR7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1166018:FAES RS11285
gene id: 1166018:FAES_RS11285
uniprot id: I0K7Y8
names: Subcellular Location Annotation
messages: Cytoplasm

1166018:FAES RS26345
gene id: 1166018:FAES_RS26345
uniprot id: I0KG98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1166018:FAES RS12280
gene id: 1166018:FAES_RS12280
uniprot id: I0K8I1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1166018:FAES RS02295
gene id: 1166018:FAES_RS02295
uniprot id: I0K2X5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1166018:FAES RS19260
gene id: 1166018:FAES_RS19260
uniprot id: I0KCE0
names: Similarity
messages: Belongs to the threonine aldolase family.

1166018:FAES RS11315
gene id: 1166018:FAES_RS11315
uniprot id: I0K7Z4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1166018:FAES RS13875
gene id: 1166018:FAES_RS13875
uniprot id: I0K9F1
names: Similarity
messages: Belongs to the peptidase S8 family.

1166018:FAES RS24620
gene id: 1166018:FAES_RS24620
uniprot id: I0KFB4
names: Similarity
messages: Belongs to the pirin family.

1166018:FAES RS10240
gene id: 1166018:FAES_RS10240
uniprot id: I0K7C9
names: Similarity
messages: Belongs to the CinA family.

1166018:FAES RS01305
gene id: 1166018:FAES_RS01305
uniprot id: I0K2B9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1166018:FAES RS07440
gene id: 1166018:FAES_RS07440
uniprot id: I0K5T7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Belongs to the glycosyl hydrolase 18 family.

1166018:FAES RS26715
gene id: 1166018:FAES_RS26715
uniprot id: I0KGH6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1166018:FAES RS25935
gene id: 1166018:FAES_RS25935
uniprot id: I0KG21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS22460
gene id: 1166018:FAES_RS22460
uniprot id: I0KE29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1166018:FAES RS11910
gene id: 1166018:FAES_RS11910
uniprot id: I0K8A7
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS12145
gene id: 1166018:FAES_RS12145
uniprot id: I0K8F5
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS03540
gene id: 1166018:FAES_RS03540
uniprot id: I0K3M1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS05860
gene id: 1166018:FAES_RS05860
uniprot id: I0K4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1166018:FAES RS25520
gene id: 1166018:FAES_RS25520
uniprot id: I0KFT8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS27580
gene id: 1166018:FAES_RS27580
uniprot id: I0KH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1166018:FAES RS02360
gene id: 1166018:FAES_RS02360
uniprot id: I0K2Y3
names: Similarity
messages: Belongs to the BshC family.

1166018:FAES RS11020
gene id: 1166018:FAES_RS11020
uniprot id: I0K7T5
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS15750
gene id: 1166018:FAES_RS15750
uniprot id: I0KAH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1166018:FAES RS13490
gene id: 1166018:FAES_RS13490
uniprot id: I0K973
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1166018:FAES RS07275
gene id: 1166018:FAES_RS07275
uniprot id: I0K5Q4
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1166018:FAES RS15695
gene id: 1166018:FAES_RS15695
uniprot id: I0KAG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS12675
gene id: 1166018:FAES_RS12675
uniprot id: I0K8R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1166018:FAES RS13935
gene id: 1166018:FAES_RS13935
uniprot id: I0K9G3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1166018:FAES RS01355
gene id: 1166018:FAES_RS01355
uniprot id: I0K2C9
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1166018:FAES RS06515
gene id: 1166018:FAES_RS06515
uniprot id: I0K5A7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS04580
gene id: 1166018:FAES_RS04580
uniprot id: I0K479
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1166018:FAES RS23545
gene id: 1166018:FAES_RS23545
uniprot id: I0KEP5
names: Similarity
messages: Belongs to the Skp family.

1166018:FAES RS14760
gene id: 1166018:FAES_RS14760
uniprot id: I0K9Y2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1166018:FAES RS02120
gene id: 1166018:FAES_RS02120
uniprot id: I0K2T7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1166018:FAES RS05760
gene id: 1166018:FAES_RS05760
uniprot id: I0K4V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1166018:FAES RS19830
gene id: 1166018:FAES_RS19830
uniprot id: I0KCQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1166018:FAES RS02140
gene id: 1166018:FAES_RS02140
uniprot id: I0K2U1
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS22505
gene id: 1166018:FAES_RS22505
uniprot id: I0KE37
names: Similarity
messages: Belongs to the UxaA family.

1166018:FAES RS27135
gene id: 1166018:FAES_RS27135
uniprot id: I0KGR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1166018:FAES RS27260
gene id: 1166018:FAES_RS27260
uniprot id: I0KGT6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS22940
gene id: 1166018:FAES_RS22940
uniprot id: I0KEC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1166018:FAES RS14425
gene id: 1166018:FAES_RS14425
uniprot id: I0K9R7
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS09445
gene id: 1166018:FAES_RS09445
uniprot id: I0K6X1
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1166018:FAES RS04160
gene id: 1166018:FAES_RS04160
uniprot id: I0K3Z3
names: Similarity
messages: Belongs to the pyruvate kinase family.

1166018:FAES RS27090
gene id: 1166018:FAES_RS27090
uniprot id: I0KGQ1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1166018:FAES RS05910
gene id: 1166018:FAES_RS05910
uniprot id: I0K4Y6
names: Similarity
messages: Belongs to the aspartokinase family.

1166018:FAES RS06220
gene id: 1166018:FAES_RS06220
uniprot id: I0K548
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS14535
gene id: 1166018:FAES_RS14535
uniprot id: I0K9T9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS02400
gene id: 1166018:FAES_RS02400
uniprot id: I0K2Z0
names: Similarity
messages: Belongs to the TrpC family.

1166018:FAES RS13510
gene id: 1166018:FAES_RS13510
uniprot id: I0K978
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1166018:FAES RS03510
gene id: 1166018:FAES_RS03510
uniprot id: I0K3L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS02095
gene id: 1166018:FAES_RS02095
uniprot id: I0K2T3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS21160
gene id: 1166018:FAES_RS21160
uniprot id: I0KDC4
names: Similarity
messages: Belongs to the CvfB family.

1166018:FAES RS22555
gene id: 1166018:FAES_RS22555
uniprot id: I0KE47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1166018:FAES RS15380
gene id: 1166018:FAES_RS15380
uniprot id: I0KAA4
names: Similarity
messages: Belongs to the peptidase S8 family.

1166018:FAES RS27815
gene id: 1166018:FAES_RS27815
uniprot id: I0KH45
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1166018:FAES RS13950
gene id: 1166018:FAES_RS13950
uniprot id: I0K9G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1166018:FAES RS10835
gene id: 1166018:FAES_RS10835
uniprot id: I0K7Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS25205
gene id: 1166018:FAES_RS25205
uniprot id: I0KFM7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1166018:FAES RS12035
gene id: 1166018:FAES_RS12035
uniprot id: I0K8D3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1166018:FAES RS14415
gene id: 1166018:FAES_RS14415
uniprot id: I0K9R5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1166018:FAES RS01375
gene id: 1166018:FAES_RS01375
uniprot id: I0K2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1166018:FAES RS24935
gene id: 1166018:FAES_RS24935
uniprot id: I0KFH5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1166018:FAES RS11410
gene id: 1166018:FAES_RS11410
uniprot id: I0K815
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS18225
gene id: 1166018:FAES_RS18225
uniprot id: I0KBV4
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS19715
gene id: 1166018:FAES_RS19715
uniprot id: I0KCM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1166018:FAES RS10550
gene id: 1166018:FAES_RS10550
uniprot id: I0K7J5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1166018:FAES RS03985
gene id: 1166018:FAES_RS03985
uniprot id: I0K3V8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS00330
gene id: 1166018:FAES_RS00330
uniprot id: I0K1S7
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1166018:FAES RS01155
gene id: 1166018:FAES_RS01155
uniprot id: I0K290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1166018:FAES RS05750
gene id: 1166018:FAES_RS05750
uniprot id: I0K4V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1166018:FAES RS00405
gene id: 1166018:FAES_RS00405
uniprot id: I0K1U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS18265
gene id: 1166018:FAES_RS18265
uniprot id: I0KBW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1166018:FAES RS00495
gene id: 1166018:FAES_RS00495
uniprot id: I0K1V9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1166018:FAES RS00560
gene id: 1166018:FAES_RS00560
uniprot id: I0K1X2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS05005
gene id: 1166018:FAES_RS05005
uniprot id: I0K4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1166018:FAES RS02355
gene id: 1166018:FAES_RS02355
uniprot id: I0K2Y2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1166018:FAES RS24375
gene id: 1166018:FAES_RS24375
uniprot id: I0KF65
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1166018:FAES RS25830
gene id: 1166018:FAES_RS25830
uniprot id: I0KG00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1166018:FAES RS20960
gene id: 1166018:FAES_RS20960
uniprot id: I0KD83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS12500
gene id: 1166018:FAES_RS12500
uniprot id: I0K8M5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS04260
gene id: 1166018:FAES_RS04260
uniprot id: I0K412
names: Similarity
messages: Belongs to the UPF0145 family.

1166018:FAES RS04120
gene id: 1166018:FAES_RS04120
uniprot id: I0K3Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1166018:FAES RS02435
gene id: 1166018:FAES_RS02435
uniprot id: I0K2Z6
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1166018:FAES RS04065
gene id: 1166018:FAES_RS04065
uniprot id: I0K3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1166018:FAES RS25535
gene id: 1166018:FAES_RS25535
uniprot id: I0KFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1166018:FAES RS05305
gene id: 1166018:FAES_RS05305
uniprot id: I0K4L9
names: Similarity
messages: Belongs to the Skp family.

1166018:FAES RS14755
gene id: 1166018:FAES_RS14755
uniprot id: I0K9Y1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS18130
gene id: 1166018:FAES_RS18130
uniprot id: I0KBT5
names: Similarity
messages: Belongs to the arginine deiminase family.

1166018:FAES RS05390
gene id: 1166018:FAES_RS05390
uniprot id: I0K4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS15640
gene id: 1166018:FAES_RS15640
uniprot id: I0KAF6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1166018:FAES RS09790
gene id: 1166018:FAES_RS09790
uniprot id: I0K741
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1166018:FAES RS08620
gene id: 1166018:FAES_RS08620
uniprot id: I0K6G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1166018:FAES RS01010
gene id: 1166018:FAES_RS01010
uniprot id: I0K263
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS25505
gene id: 1166018:FAES_RS25505
uniprot id: I0KFT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1166018:FAES RS05095
gene id: 1166018:FAES_RS05095
uniprot id: I0K4H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1166018:FAES RS15560
gene id: 1166018:FAES_RS15560
uniprot id: I0KAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1166018:FAES RS04095
gene id: 1166018:FAES_RS04095
uniprot id: I0K3Y0
names: Similarity
messages: Belongs to the citrate synthase family.

1166018:FAES RS16025
gene id: 1166018:FAES_RS16025
uniprot id: I0KAN5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS06735
gene id: 1166018:FAES_RS06735
uniprot id: I0K5F1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1166018:FAES RS08195
gene id: 1166018:FAES_RS08195
uniprot id: I0K687
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1166018:FAES RS18015
gene id: 1166018:FAES_RS18015
uniprot id: I0KBR1
names: Similarity
messages: Belongs to the UPF0047 family.

1166018:FAES RS05960
gene id: 1166018:FAES_RS05960
uniprot id: I0K4Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS22665
gene id: 1166018:FAES_RS22665
uniprot id: I0KE71
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS08210
gene id: 1166018:FAES_RS08210
uniprot id: I0K690
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1166018:FAES RS14365
gene id: 1166018:FAES_RS14365
uniprot id: I0K9Q5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1166018:FAES RS17140
gene id: 1166018:FAES_RS17140
uniprot id: I0KB90
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1166018:FAES RS24455
gene id: 1166018:FAES_RS24455
uniprot id: I0KF81
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1166018:FAES RS08520
gene id: 1166018:FAES_RS08520
uniprot id: I0K6E7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1166018:FAES RS17720
gene id: 1166018:FAES_RS17720
uniprot id: I0KBK4
names: Similarity
messages: Belongs to the manganese catalase family.

1166018:FAES RS13615
gene id: 1166018:FAES_RS13615
uniprot id: I0K9A0
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS10095
gene id: 1166018:FAES_RS10095
uniprot id: I0K7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS02450
gene id: 1166018:FAES_RS02450
uniprot id: I0K2Z9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1166018:FAES RS08765
gene id: 1166018:FAES_RS08765
uniprot id: I0K6J4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1166018:FAES RS13650
gene id: 1166018:FAES_RS13650
uniprot id: I0K9A7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1166018:FAES RS05040
gene id: 1166018:FAES_RS05040
uniprot id: I0K4G5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1166018:FAES RS00455
gene id: 1166018:FAES_RS00455
uniprot id: I0K1V1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS12725
gene id: 1166018:FAES_RS12725
uniprot id: I0K8S2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1166018:FAES RS18630
gene id: 1166018:FAES_RS18630
uniprot id: I0KC27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1166018:FAES RS06715
gene id: 1166018:FAES_RS06715
uniprot id: I0K5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1166018:FAES RS27140
gene id: 1166018:FAES_RS27140
uniprot id: I0KGR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1166018:FAES RS28205
gene id: 1166018:FAES_RS28205
uniprot id: I0KHB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane

1166018:FAES RS05480
gene id: 1166018:FAES_RS05480
uniprot id: I0K4Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1166018:FAES RS06890
gene id: 1166018:FAES_RS06890
uniprot id: I0K5H9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1166018:FAES RS23705
gene id: 1166018:FAES_RS23705
uniprot id: I0KES9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1166018:FAES RS09485
gene id: 1166018:FAES_RS09485
uniprot id: I0K6X9
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1166018:FAES RS28675
gene id: 1166018:FAES_RS28675
uniprot id: I0KHL4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1166018:FAES RS18875
gene id: 1166018:FAES_RS18875
uniprot id: I0KC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS17540
gene id: 1166018:FAES_RS17540
uniprot id: I0KBH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1166018:FAES RS12715
gene id: 1166018:FAES_RS12715
uniprot id: I0K8S0
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1166018:FAES RS12915
gene id: 1166018:FAES_RS12915
uniprot id: I0K8V9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1166018:FAES RS21320
gene id: 1166018:FAES_RS21320
uniprot id: I0KDF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS05035
gene id: 1166018:FAES_RS05035
uniprot id: I0K4G4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1166018:FAES RS24700
gene id: 1166018:FAES_RS24700
uniprot id: I0KFD0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1166018:FAES RS19840
gene id: 1166018:FAES_RS19840
uniprot id: I0KCQ3
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS06440
gene id: 1166018:FAES_RS06440
uniprot id: I0K591
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS16125
gene id: 1166018:FAES_RS16125
uniprot id: I0KAQ6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS04705
gene id: 1166018:FAES_RS04705
uniprot id: I0K4A2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS02265
gene id: 1166018:FAES_RS02265
uniprot id: I0K2W9
names: Similarity
messages: Belongs to the barstar family.

1166018:FAES RS12420
gene id: 1166018:FAES_RS12420
uniprot id: I0K8K8
names: Similarity
messages: Belongs to the SufE family.

1166018:FAES RS08935
gene id: 1166018:FAES_RS08935
uniprot id: I0K6M8
names: Similarity
messages: Belongs to the universal stress protein A family.

1166018:FAES RS04290
gene id: 1166018:FAES_RS04290
uniprot id: I0K419
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS07775
gene id: 1166018:FAES_RS07775
uniprot id: I0K604
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1166018:FAES RS28175
gene id: 1166018:FAES_RS28175
uniprot id: I0KHB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS26350
gene id: 1166018:FAES_RS26350
uniprot id: I0KG99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1166018:FAES RS07030
gene id: 1166018:FAES_RS07030
uniprot id: I0K5K7
names: Similarity
messages: Belongs to the DinB family.

1166018:FAES RS13595
gene id: 1166018:FAES_RS13595
uniprot id: I0K996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS00030
gene id: 1166018:FAES_RS00030
uniprot id: I0K1L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1166018:FAES RS12225
gene id: 1166018:FAES_RS12225
uniprot id: I0K8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1166018:FAES RS05565
gene id: 1166018:FAES_RS05565
uniprot id: I0K4R6
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1166018:FAES RS10980
gene id: 1166018:FAES_RS10980
uniprot id: I0K7S7
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS19540
gene id: 1166018:FAES_RS19540
uniprot id: I0KCJ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1166018:FAES RS18115
gene id: 1166018:FAES_RS18115
uniprot id: I0KBT2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1166018:FAES RS18725
gene id: 1166018:FAES_RS18725
uniprot id: I0KC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS07180
gene id: 1166018:FAES_RS07180
uniprot id: I0K5N6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1166018:FAES RS11845
gene id: 1166018:FAES_RS11845
uniprot id: I0K894
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1166018:FAES RS22120
gene id: 1166018:FAES_RS22120
uniprot id: I0KDW2
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1166018:FAES RS26465
gene id: 1166018:FAES_RS26465
uniprot id: I0KGC2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1166018:FAES RS11925
gene id: 1166018:FAES_RS11925
uniprot id: I0K8B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS03660
gene id: 1166018:FAES_RS03660
uniprot id: I0K3P5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1166018:FAES RS11215
gene id: 1166018:FAES_RS11215
uniprot id: I0K7X4
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS13785
gene id: 1166018:FAES_RS13785
uniprot id: I0K9D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1166018:FAES RS00130
gene id: 1166018:FAES_RS00130
uniprot id: I0K1N7
names: Similarity
messages: Belongs to the ComB family.

1166018:FAES RS05285
gene id: 1166018:FAES_RS05285
uniprot id: I0K4L5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1166018:FAES RS05490
gene id: 1166018:FAES_RS05490
uniprot id: I0K4Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1166018:FAES RS03615
gene id: 1166018:FAES_RS03615
uniprot id: I0K3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1166018:FAES RS19875
gene id: 1166018:FAES_RS19875
uniprot id: I0KCR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1166018:FAES RS15480
gene id: 1166018:FAES_RS15480
uniprot id: I0KAC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1166018:FAES RS07365
gene id: 1166018:FAES_RS07365
uniprot id: I0K5S1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1166018:FAES RS21815
gene id: 1166018:FAES_RS21815
uniprot id: I0KDP9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1166018:FAES RS01045
gene id: 1166018:FAES_RS01045
uniprot id: I0K270
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS07265
gene id: 1166018:FAES_RS07265
uniprot id: I0K5Q2
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1166018:FAES RS11805
gene id: 1166018:FAES_RS11805
uniprot id: I0K886
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1166018:FAES RS27620
gene id: 1166018:FAES_RS27620
uniprot id: I0KH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1166018:FAES RS13120
gene id: 1166018:FAES_RS13120
uniprot id: I0K900
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1166018:FAES RS02460
gene id: 1166018:FAES_RS02460
uniprot id: I0K301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1166018:FAES RS17070
gene id: 1166018:FAES_RS17070
uniprot id: I0KB77
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1166018:FAES RS14870
gene id: 1166018:FAES_RS14870
uniprot id: I0KA04
names: Similarity
messages: Belongs to the thioredoxin family.

1166018:FAES RS26420
gene id: 1166018:FAES_RS26420
uniprot id: I0KGB3
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS15150
gene id: 1166018:FAES_RS15150
uniprot id: I0KA59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1166018:FAES RS06975
gene id: 1166018:FAES_RS06975
uniprot id: I0K5J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1166018:FAES RS16850
gene id: 1166018:FAES_RS16850
uniprot id: I0KB40
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1166018:FAES RS08995
gene id: 1166018:FAES_RS08995
uniprot id: I0K6P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1166018:FAES RS18095
gene id: 1166018:FAES_RS18095
uniprot id: I0KBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1166018:FAES RS19350
gene id: 1166018:FAES_RS19350
uniprot id: I0KCF8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1166018:FAES RS17280
gene id: 1166018:FAES_RS17280
uniprot id: I0KBB7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS01605
gene id: 1166018:FAES_RS01605
uniprot id: I0K2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS06395
gene id: 1166018:FAES_RS06395
uniprot id: I0K581
names: Subcellular Location Annotation
messages: Cytoplasm

1166018:FAES RS01340
gene id: 1166018:FAES_RS01340
uniprot id: I0K2C6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1166018:FAES RS01600
gene id: 1166018:FAES_RS01600
uniprot id: I0K2H7
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS05155
gene id: 1166018:FAES_RS05155
uniprot id: I0K4I8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS15235
gene id: 1166018:FAES_RS15235
uniprot id: I0KA76
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1166018:FAES RS05470
gene id: 1166018:FAES_RS05470
uniprot id: I0K4P8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1166018:FAES RS22510
gene id: 1166018:FAES_RS22510
uniprot id: I0KE38
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1166018:FAES RS26370
gene id: 1166018:FAES_RS26370
uniprot id: I0KGA3
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS13985
gene id: 1166018:FAES_RS13985
uniprot id: I0K9H4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1166018:FAES RS07730
gene id: 1166018:FAES_RS07730
uniprot id: I0K5Z5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS07780
gene id: 1166018:FAES_RS07780
uniprot id: I0K605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS00930
gene id: 1166018:FAES_RS00930
uniprot id: I0K247
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1166018:FAES RS24510
gene id: 1166018:FAES_RS24510
uniprot id: I0KF92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1166018:FAES RS05310
gene id: 1166018:FAES_RS05310
uniprot id: I0K4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1166018:FAES RS22860
gene id: 1166018:FAES_RS22860
uniprot id: I0KEB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS21995
gene id: 1166018:FAES_RS21995
uniprot id: I0KDT7
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS06615
gene id: 1166018:FAES_RS06615
uniprot id: I0K5C6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS23600
gene id: 1166018:FAES_RS23600
uniprot id: I0KEQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1166018:FAES RS11225
gene id: 1166018:FAES_RS11225
uniprot id: I0K7X6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS22100
gene id: 1166018:FAES_RS22100
uniprot id: I0KDV8
names: Similarity
messages: Belongs to the pirin family.

1166018:FAES RS09050
gene id: 1166018:FAES_RS09050
uniprot id: I0K6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1166018:FAES RS14265
gene id: 1166018:FAES_RS14265
uniprot id: I0K9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1166018:FAES RS19435
gene id: 1166018:FAES_RS19435
uniprot id: I0KCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS27180
gene id: 1166018:FAES_RS27180
uniprot id: I0KGS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1166018:FAES RS13610
gene id: 1166018:FAES_RS13610
uniprot id: I0K999
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS06385
gene id: 1166018:FAES_RS06385
uniprot id: I0K578
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

1166018:FAES RS15090
gene id: 1166018:FAES_RS15090
uniprot id: I0KA47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1166018:FAES RS25855
gene id: 1166018:FAES_RS25855
uniprot id: I0KG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS19485
gene id: 1166018:FAES_RS19485
uniprot id: I0KCI4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1166018:FAES RS06575
gene id: 1166018:FAES_RS06575
uniprot id: I0K5B8
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1166018:FAES RS00475
gene id: 1166018:FAES_RS00475
uniprot id: I0K1V5
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS22225
gene id: 1166018:FAES_RS22225
uniprot id: I0KDY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1166018:FAES RS13185
gene id: 1166018:FAES_RS13185
uniprot id: I0K913
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS14375
gene id: 1166018:FAES_RS14375
uniprot id: I0K9Q7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1166018:FAES RS18155
gene id: 1166018:FAES_RS18155
uniprot id: I0KBU0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS11000
gene id: 1166018:FAES_RS11000
uniprot id: I0K7T1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS11350
gene id: 1166018:FAES_RS11350
uniprot id: I0K801
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS04520
gene id: 1166018:FAES_RS04520
uniprot id: I0K467
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1166018:FAES RS07635
gene id: 1166018:FAES_RS07635
uniprot id: I0K5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS12140
gene id: 1166018:FAES_RS12140
uniprot id: I0K8F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS17615
gene id: 1166018:FAES_RS17615
uniprot id: I0KBI5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1166018:FAES RS10090
gene id: 1166018:FAES_RS10090
uniprot id: I0K7A0
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS20930
gene id: 1166018:FAES_RS20930
uniprot id: I0KD77
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS18900
gene id: 1166018:FAES_RS18900
uniprot id: I0KC76
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1166018:FAES RS19460
gene id: 1166018:FAES_RS19460
uniprot id: I0KCI0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1166018:FAES RS04310
gene id: 1166018:FAES_RS04310
uniprot id: I0K424
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS08290
gene id: 1166018:FAES_RS08290
uniprot id: I0K6A4
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS04735
gene id: 1166018:FAES_RS04735
uniprot id: I0K4A8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1166018:FAES RS20125
gene id: 1166018:FAES_RS20125
uniprot id: I0KCV5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1166018:FAES RS26915
gene id: 1166018:FAES_RS26915
uniprot id: I0KGL6
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS24125
gene id: 1166018:FAES_RS24125
uniprot id: I0KF15
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1166018:FAES RS07705
gene id: 1166018:FAES_RS07705
uniprot id: I0K5Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1166018:FAES RS21165
gene id: 1166018:FAES_RS21165
uniprot id: I0KDC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1166018:FAES RS06490
gene id: 1166018:FAES_RS06490
uniprot id: I0K5A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS02395
gene id: 1166018:FAES_RS02395
uniprot id: I0K2Y9
names: Similarity
messages: Belongs to the TrpF family.

1166018:FAES RS08805
gene id: 1166018:FAES_RS08805
uniprot id: I0K6K2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS17425
gene id: 1166018:FAES_RS17425
uniprot id: I0KBE7
names: Similarity
messages: Belongs to the Dps family.

1166018:FAES RS08475
gene id: 1166018:FAES_RS08475
uniprot id: I0K6D7
names: Similarity
messages: Belongs to the UPF0303 family.

1166018:FAES RS03595
gene id: 1166018:FAES_RS03595
uniprot id: I0K3N2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1166018:FAES RS04535
gene id: 1166018:FAES_RS04535
uniprot id: I0K470
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1166018:FAES RS22855
gene id: 1166018:FAES_RS22855
uniprot id: I0KEA9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS11890
gene id: 1166018:FAES_RS11890
uniprot id: I0K8A3
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1166018:FAES RS05840
gene id: 1166018:FAES_RS05840
uniprot id: I0K4X1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1166018:FAES RS27280
gene id: 1166018:FAES_RS27280
uniprot id: I0KGU0
names: Similarity
messages: Belongs to the peptidase S33 family.

1166018:FAES RS21510
gene id: 1166018:FAES_RS21510
uniprot id: I0KDJ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS02010
gene id: 1166018:FAES_RS02010
uniprot id: I0K2R5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1166018:FAES RS00105
gene id: 1166018:FAES_RS00105
uniprot id: I0K1N2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS05745
gene id: 1166018:FAES_RS05745
uniprot id: I0K4V2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1166018:FAES RS04680
gene id: 1166018:FAES_RS04680
uniprot id: I0K497
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1166018:FAES RS22890
gene id: 1166018:FAES_RS22890
uniprot id: I0KEB7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS10780
gene id: 1166018:FAES_RS10780
uniprot id: I0K7P0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS02930
gene id: 1166018:FAES_RS02930
uniprot id: I0K398
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS10595
gene id: 1166018:FAES_RS10595
uniprot id: I0K7K4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1166018:FAES RS00275
gene id: 1166018:FAES_RS00275
uniprot id: I0K1R6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1166018:FAES RS07940
gene id: 1166018:FAES_RS07940
uniprot id: I0K638
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1166018:FAES RS04570
gene id: 1166018:FAES_RS04570
uniprot id: I0K477
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS17550
gene id: 1166018:FAES_RS17550
uniprot id: I0KBH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1166018:FAES RS27630
gene id: 1166018:FAES_RS27630
uniprot id: I0KH09
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1166018:FAES RS12505
gene id: 1166018:FAES_RS12505
uniprot id: I0K8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS14340
gene id: 1166018:FAES_RS14340
uniprot id: I0K9Q0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1166018:FAES RS13735
gene id: 1166018:FAES_RS13735
uniprot id: I0K9C5
names: Similarity
messages: Belongs to the ribulokinase family.

1166018:FAES RS00450
gene id: 1166018:FAES_RS00450
uniprot id: I0K1V0
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS18955
gene id: 1166018:FAES_RS18955
uniprot id: I0KC87
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1166018:FAES RS11140
gene id: 1166018:FAES_RS11140
uniprot id: I0K7V7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1166018:FAES RS25665
gene id: 1166018:FAES_RS25665
uniprot id: I0KFW7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1166018:FAES RS26960
gene id: 1166018:FAES_RS26960
uniprot id: I0KGM5
names: Similarity
messages: Belongs to the peptidase S51 family.

1166018:FAES RS17975
gene id: 1166018:FAES_RS17975
uniprot id: I0KBQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS12130
gene id: 1166018:FAES_RS12130
uniprot id: I0K8F2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1166018:FAES RS18035
gene id: 1166018:FAES_RS18035
uniprot id: I0KBR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS28085
gene id: 1166018:FAES_RS28085
uniprot id: I0KH93
names: Similarity
messages: Belongs to the Dps family.

1166018:FAES RS14620
gene id: 1166018:FAES_RS14620
uniprot id: I0K9V6
names: Subcellular Location Annotation
messages: Cell inner membrane

1166018:FAES RS12115
gene id: 1166018:FAES_RS12115
uniprot id: I0K8E9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1166018:FAES RS27450
gene id: 1166018:FAES_RS27450
uniprot id: I0KGX6
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1166018:FAES RS13585
gene id: 1166018:FAES_RS13585
uniprot id: I0K994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS13575
gene id: 1166018:FAES_RS13575
uniprot id: I0K992
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1166018:FAES RS04585
gene id: 1166018:FAES_RS04585
uniprot id: I0K480
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1166018:FAES RS04180
gene id: 1166018:FAES_RS04180
uniprot id: I0K3Z7
names: Similarity
messages: Belongs to the peptidase S41A family.

1166018:FAES RS02815
gene id: 1166018:FAES_RS02815
uniprot id: I0K375
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS15960
gene id: 1166018:FAES_RS15960
uniprot id: I0KAM2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS06210
gene id: 1166018:FAES_RS06210
uniprot id: I0K546
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1166018:FAES RS08945
gene id: 1166018:FAES_RS08945
uniprot id: I0K6N1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1166018:FAES RS14560
gene id: 1166018:FAES_RS14560
uniprot id: I0K9U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1166018:FAES RS01550
gene id: 1166018:FAES_RS01550
uniprot id: I0K2G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS19400
gene id: 1166018:FAES_RS19400
uniprot id: I0KCG8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS27205
gene id: 1166018:FAES_RS27205
uniprot id: I0KGS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1166018:FAES RS26275
gene id: 1166018:FAES_RS26275
uniprot id: I0KG83
names: Similarity
messages: Belongs to the AAA ATPase family.

1166018:FAES RS21070
gene id: 1166018:FAES_RS21070
uniprot id: I0KDA6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1166018:FAES RS13500
gene id: 1166018:FAES_RS13500
uniprot id: I0K976
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1166018:FAES RS10445
gene id: 1166018:FAES_RS10445
uniprot id: I0K7H4
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS06075
gene id: 1166018:FAES_RS06075
uniprot id: I0K519
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1166018:FAES RS21795
gene id: 1166018:FAES_RS21795
uniprot id: I0KDP7
names: Similarity
messages: Belongs to the peptidase S9C family.

1166018:FAES RS14025
gene id: 1166018:FAES_RS14025
uniprot id: I0K9I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1166018:FAES RS00795
gene id: 1166018:FAES_RS00795
uniprot id: I0K219
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS03465
gene id: 1166018:FAES_RS03465
uniprot id: I0K3K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

1166018:FAES RS10940
gene id: 1166018:FAES_RS10940
uniprot id: I0K7S3
names: Similarity
messages: Belongs to the peptidase M16 family.

1166018:FAES RS21305
gene id: 1166018:FAES_RS21305
uniprot id: I0KDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1166018:FAES RS00550
gene id: 1166018:FAES_RS00550
uniprot id: I0K1X0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1166018:FAES RS27160
gene id: 1166018:FAES_RS27160
uniprot id: I0KGR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1166018:FAES RS08050
gene id: 1166018:FAES_RS08050
uniprot id: I0K659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1166018:FAES RS05380
gene id: 1166018:FAES_RS05380
uniprot id: I0K4N4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1166018:FAES RS10245
gene id: 1166018:FAES_RS10245
uniprot id: I0K7D0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1166018:FAES RS21645
gene id: 1166018:FAES_RS21645
uniprot id: I0KDL7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS13990
gene id: 1166018:FAES_RS13990
uniprot id: I0K9H5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS13210
gene id: 1166018:FAES_RS13210
uniprot id: I0K918
names: Similarity
messages: Belongs to the SCO1/2 family.

1166018:FAES RS23745
gene id: 1166018:FAES_RS23745
uniprot id: I0KET7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1166018:FAES RS27960
gene id: 1166018:FAES_RS27960
uniprot id: I0KH72
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS16830
gene id: 1166018:FAES_RS16830
uniprot id: I0KB36
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1166018:FAES RS09000
gene id: 1166018:FAES_RS09000
uniprot id: I0K6P2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS10845
gene id: 1166018:FAES_RS10845
uniprot id: I0K7Q3
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1166018:FAES RS04660
gene id: 1166018:FAES_RS04660
uniprot id: I0K493
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS22430
gene id: 1166018:FAES_RS22430
uniprot id: I0KE23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1166018:FAES RS01765
gene id: 1166018:FAES_RS01765
uniprot id: I0K2L3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1166018:FAES RS29010
gene id: 1166018:FAES_RS29010
uniprot id: I0K9W6
names: Similarity
messages: Belongs to the ice-binding protein family.

1166018:FAES RS01975
gene id: 1166018:FAES_RS01975
uniprot id: I0K2Q8
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1166018:FAES RS26930
gene id: 1166018:FAES_RS26930
uniprot id: I0KGL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1166018:FAES RS09960
gene id: 1166018:FAES_RS09960
uniprot id: I0K775
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1166018:FAES RS23195
gene id: 1166018:FAES_RS23195
uniprot id: I0KEH8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS13590
gene id: 1166018:FAES_RS13590
uniprot id: I0K995
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS09130
gene id: 1166018:FAES_RS09130
uniprot id: I0K6R7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1166018:FAES RS02890
gene id: 1166018:FAES_RS02890
uniprot id: I0K390
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1166018:FAES RS27565
gene id: 1166018:FAES_RS27565
uniprot id: I0KGZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1166018:FAES RS21375
gene id: 1166018:FAES_RS21375
uniprot id: I0KDG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1166018:FAES RS13720
gene id: 1166018:FAES_RS13720
uniprot id: I0K9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1166018:FAES RS04655
gene id: 1166018:FAES_RS04655
uniprot id: I0K492
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS03155
gene id: 1166018:FAES_RS03155
uniprot id: I0K3E2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1166018:FAES RS18070
gene id: 1166018:FAES_RS18070
uniprot id: I0KBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1166018:FAES RS13400
gene id: 1166018:FAES_RS13400
uniprot id: I0K957
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS18915
gene id: 1166018:FAES_RS18915
uniprot id: I0KC79
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS05655
gene id: 1166018:FAES_RS05655
uniprot id: I0K4T4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1166018:FAES RS11900
gene id: 1166018:FAES_RS11900
uniprot id: I0K8A5
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS18220
gene id: 1166018:FAES_RS18220
uniprot id: I0KBV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS21210
gene id: 1166018:FAES_RS21210
uniprot id: I0KDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1166018:FAES RS17330
gene id: 1166018:FAES_RS17330
uniprot id: I0KBC8
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS16020
gene id: 1166018:FAES_RS16020
uniprot id: I0KAN4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1166018:FAES RS19370
gene id: 1166018:FAES_RS19370
uniprot id: I0KCG2
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS04850
gene id: 1166018:FAES_RS04850
uniprot id: I0K4D1
names: Similarity
messages: Belongs to the RutC family.

1166018:FAES RS12210
gene id: 1166018:FAES_RS12210
uniprot id: I0K8G8
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS15105
gene id: 1166018:FAES_RS15105
uniprot id: I0KA50
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1166018:FAES RS18150
gene id: 1166018:FAES_RS18150
uniprot id: I0KBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1166018:FAES RS01760
gene id: 1166018:FAES_RS01760
uniprot id: I0K2L2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1166018:FAES RS04695
gene id: 1166018:FAES_RS04695
uniprot id: I0K4A0
names: Similarity
messages: Belongs to the IMPACT family.

1166018:FAES RS12950
gene id: 1166018:FAES_RS12950
uniprot id: I0K8W7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1166018:FAES RS03860
gene id: 1166018:FAES_RS03860
uniprot id: I0K3T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1166018:FAES RS24575
gene id: 1166018:FAES_RS24575
uniprot id: I0KFA5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1166018:FAES RS14085
gene id: 1166018:FAES_RS14085
uniprot id: I0K9J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1166018:FAES RS24525
gene id: 1166018:FAES_RS24525
uniprot id: I0KF95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1166018:FAES RS21355
gene id: 1166018:FAES_RS21355
uniprot id: I0KDG1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1166018:FAES RS01030
gene id: 1166018:FAES_RS01030
uniprot id: I0K267
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS28090
gene id: 1166018:FAES_RS28090
uniprot id: I0KH94
names: Similarity
messages: Belongs to the Dps family.

1166018:FAES RS08125
gene id: 1166018:FAES_RS08125
uniprot id: I0K674
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1166018:FAES RS07100
gene id: 1166018:FAES_RS07100
uniprot id: I0K5M0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1166018:FAES RS17950
gene id: 1166018:FAES_RS17950
uniprot id: I0KBP9
names: Similarity
messages: Belongs to the peptidase S66 family.

1166018:FAES RS27595
gene id: 1166018:FAES_RS27595
uniprot id: I0KH03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1166018:FAES RS20680
gene id: 1166018:FAES_RS20680
uniprot id: I0KD31
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1166018:FAES RS26775
gene id: 1166018:FAES_RS26775
uniprot id: I0KGI7
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS27645
gene id: 1166018:FAES_RS27645
uniprot id: I0KH12
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS06090
gene id: 1166018:FAES_RS06090
uniprot id: I0K522
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS26660
gene id: 1166018:FAES_RS26660
uniprot id: I0KGG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1166018:FAES RS17335
gene id: 1166018:FAES_RS17335
uniprot id: I0KBC9
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS14875
gene id: 1166018:FAES_RS14875
uniprot id: I0KA05
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1166018:FAES RS02750
gene id: 1166018:FAES_RS02750
uniprot id: I0K362
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS25170
gene id: 1166018:FAES_RS25170
uniprot id: I0KFM0
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

1166018:FAES RS27615
gene id: 1166018:FAES_RS27615
uniprot id: I0KH06
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS26745
gene id: 1166018:FAES_RS26745
uniprot id: I0KGI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1166018:FAES RS14665
gene id: 1166018:FAES_RS14665
uniprot id: I0K9W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS06880
gene id: 1166018:FAES_RS06880
uniprot id: I0K5H7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS10065
gene id: 1166018:FAES_RS10065
uniprot id: I0K795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1166018:FAES RS01145
gene id: 1166018:FAES_RS01145
uniprot id: I0K288
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1166018:FAES RS22275
gene id: 1166018:FAES_RS22275
uniprot id: I0KDZ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

1166018:FAES RS22755
gene id: 1166018:FAES_RS22755
uniprot id: I0KE87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1166018:FAES RS13730
gene id: 1166018:FAES_RS13730
uniprot id: I0K9C4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1166018:FAES RS15830
gene id: 1166018:FAES_RS15830
uniprot id: I0KAJ7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1166018:FAES RS24380
gene id: 1166018:FAES_RS24380
uniprot id: I0KF66
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS25690
gene id: 1166018:FAES_RS25690
uniprot id: I0KFX2
names: Similarity
messages: Belongs to the peptidase S8 family.

1166018:FAES RS26825
gene id: 1166018:FAES_RS26825
uniprot id: I0KGJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1166018:FAES RS01345
gene id: 1166018:FAES_RS01345
uniprot id: I0K2C7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1166018:FAES RS21860
gene id: 1166018:FAES_RS21860
uniprot id: I0KDQ9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS01165
gene id: 1166018:FAES_RS01165
uniprot id: I0K292
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1166018:FAES RS27240
gene id: 1166018:FAES_RS27240
uniprot id: I0KGT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1166018:FAES RS27085
gene id: 1166018:FAES_RS27085
uniprot id: I0KGQ0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1166018:FAES RS22965
gene id: 1166018:FAES_RS22965
uniprot id: I0KED1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS11150
gene id: 1166018:FAES_RS11150
uniprot id: I0K7W0
names: Similarity
messages: Belongs to the LOG family.

1166018:FAES RS01520
gene id: 1166018:FAES_RS01520
uniprot id: I0K2G2
names: Similarity
messages: Belongs to the GARS family.

1166018:FAES RS02260
gene id: 1166018:FAES_RS02260
uniprot id: I0K2W8
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1166018:FAES RS06720
gene id: 1166018:FAES_RS06720
uniprot id: I0K5E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1166018:FAES RS07685
gene id: 1166018:FAES_RS07685
uniprot id: I0K5Y4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1166018:FAES RS07250
gene id: 1166018:FAES_RS07250
uniprot id: I0K5Q0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1166018:FAES RS05900
gene id: 1166018:FAES_RS05900
uniprot id: I0K4Y3
names: Similarity
messages: Belongs to the YfgM family.

1166018:FAES RS27245
gene id: 1166018:FAES_RS27245
uniprot id: I0KGT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1166018:FAES RS24705
gene id: 1166018:FAES_RS24705
uniprot id: I0KFD1
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS15615
gene id: 1166018:FAES_RS15615
uniprot id: I0KAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1166018:FAES RS28795
gene id: 1166018:FAES_RS28795
uniprot id: I0KHN8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1166018:FAES RS14860
gene id: 1166018:FAES_RS14860
uniprot id: I0KA02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1166018:FAES RS13215
gene id: 1166018:FAES_RS13215
uniprot id: I0K919
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1166018:FAES RS16015
gene id: 1166018:FAES_RS16015
uniprot id: I0KAN3
names: Subcellular Location Annotation
messages: Membrane

1166018:FAES RS21010
gene id: 1166018:FAES_RS21010
uniprot id: I0KD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS10635
gene id: 1166018:FAES_RS10635
uniprot id: I0K7L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1166018:FAES RS10130
gene id: 1166018:FAES_RS10130
uniprot id: I0K7A8
names: Similarity
messages: Belongs to the SusD family.

1166018:FAES RS08085
gene id: 1166018:FAES_RS08085
uniprot id: I0K665
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1166018:FAES RS15820
gene id: 1166018:FAES_RS15820
uniprot id: I0KAJ4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1166018:FAES RS02220
gene id: 1166018:FAES_RS02220
uniprot id: I0K2V9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1166018:FAES RS11085
gene id: 1166018:FAES_RS11085
uniprot id: I0K7U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1166018:FAES RS08460
gene id: 1166018:FAES_RS08460
uniprot id: I0K6D3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS25355
gene id: 1166018:FAES_RS25355
uniprot id: I0KFQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1166018:FAES RS21900
gene id: 1166018:FAES_RS21900
uniprot id: I0KDR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1166018:FAES RS07325
gene id: 1166018:FAES_RS07325
uniprot id: I0K5R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1166018:FAES RS04950
gene id: 1166018:FAES_RS04950
uniprot id: I0K4F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1166018:FAES RS04090
gene id: 1166018:FAES_RS04090
uniprot id: I0K3X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1166018:FAES RS10760
gene id: 1166018:FAES_RS10760
uniprot id: I0K7N6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1166018:FAES RS00205
gene id: 1166018:FAES_RS00205
uniprot id: I0K1Q1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1166018:FAES RS21650
gene id: 1166018:FAES_RS21650
uniprot id: I0KDL8
names: Similarity
messages: Belongs to the peptidase M13 family.