1163748:MARHY RS11325
gene id: 1163748:MARHY_RS11325
uniprot id: H8W938
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1163748:MARHY RS04000
gene id: 1163748:MARHY_RS04000
uniprot id: H8W6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1163748:MARHY RS11195
gene id: 1163748:MARHY_RS11195
uniprot id: H8W8K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163748:MARHY RS10070
gene id: 1163748:MARHY_RS10070
uniprot id: H8W6I5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

1163748:MARHY RS10725
gene id: 1163748:MARHY_RS10725
uniprot id: H8W7U2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1163748:MARHY RS09660
gene id: 1163748:MARHY_RS09660
uniprot id: H8W5U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS04990
gene id: 1163748:MARHY_RS04990
uniprot id: H8W887
names: Similarity
messages: Belongs to the YjdM family.

1163748:MARHY RS05265
gene id: 1163748:MARHY_RS05265
uniprot id: H8W8V3
names: Similarity
messages: Belongs to the HIBADH-related family.

1163748:MARHY RS02865
gene id: 1163748:MARHY_RS02865
uniprot id: H8W488
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1163748:MARHY RS09650
gene id: 1163748:MARHY_RS09650
uniprot id: H8W5T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1163748:MARHY RS15705
gene id: 1163748:MARHY_RS15705
uniprot id: H8W5Y1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1163748:MARHY RS11100
gene id: 1163748:MARHY_RS11100
uniprot id: H8W8I0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1163748:MARHY RS03220
gene id: 1163748:MARHY_RS03220
uniprot id: H8W4X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1163748:MARHY RS02500
gene id: 1163748:MARHY_RS02500
uniprot id: H8WEG4
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1163748:MARHY RS14820
gene id: 1163748:MARHY_RS14820
uniprot id: H8WEY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1163748:MARHY RS11130
gene id: 1163748:MARHY_RS11130
uniprot id: H8W8I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1163748:MARHY RS01125
gene id: 1163748:MARHY_RS01125
uniprot id: H8WC97
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS11800
gene id: 1163748:MARHY_RS11800
uniprot id: H8W9T6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1163748:MARHY RS01735
gene id: 1163748:MARHY_RS01735
uniprot id: H8WD31
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS02265
gene id: 1163748:MARHY_RS02265
uniprot id: H8WEB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1163748:MARHY RS15015
gene id: 1163748:MARHY_RS15015
uniprot id: H8W4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163748:MARHY RS01500
gene id: 1163748:MARHY_RS01500
uniprot id: H8WCY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS17425
gene id: 1163748:MARHY_RS17425
uniprot id: H8W8S9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1163748:MARHY RS00705
gene id: 1163748:MARHY_RS00705
uniprot id: H8WBK2
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1163748:MARHY RS11760
gene id: 1163748:MARHY_RS11760
uniprot id: H8W9S8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS11000
gene id: 1163748:MARHY_RS11000
uniprot id: H8W8G2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1163748:MARHY RS00315
gene id: 1163748:MARHY_RS00315
uniprot id: H8WAW0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1163748:MARHY RS03880
gene id: 1163748:MARHY_RS03880
uniprot id: H8W677
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1163748:MARHY RS09995
gene id: 1163748:MARHY_RS09995
uniprot id: H8W6H0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1163748:MARHY RS07835
gene id: 1163748:MARHY_RS07835
uniprot id: H8WD98
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1163748:MARHY RS01600
gene id: 1163748:MARHY_RS01600
uniprot id: H8WD05
names: Similarity
messages: Belongs to the MQO family.

1163748:MARHY RS06625
gene id: 1163748:MARHY_RS06625
uniprot id: H8WB69
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1163748:MARHY RS11420
gene id: 1163748:MARHY_RS11420
uniprot id: H8W952
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1163748:MARHY RS12750
gene id: 1163748:MARHY_RS12750
uniprot id: H8WBF0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1163748:MARHY RS08285
gene id: 1163748:MARHY_RS08285
uniprot id: H8WE04
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS06300
gene id: 1163748:MARHY_RS06300
uniprot id: H8WAI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1163748:MARHY RS06555
gene id: 1163748:MARHY_RS06555
uniprot id: H8WB55
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1163748:MARHY RS16925
gene id: 1163748:MARHY_RS16925
uniprot id: H8W815
names: Similarity
messages: Belongs to the histone deacetylase family.

1163748:MARHY RS17865
gene id: 1163748:MARHY_RS17865
uniprot id: H8W9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1163748:MARHY RS10735
gene id: 1163748:MARHY_RS10735
uniprot id: H8W7U4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1163748:MARHY RS12565
gene id: 1163748:MARHY_RS12565
uniprot id: H8WBB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1163748:MARHY RS01625
gene id: 1163748:MARHY_RS01625
uniprot id: H8WD09
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS04800
gene id: 1163748:MARHY_RS04800
uniprot id: H8W7N5
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS00770
gene id: 1163748:MARHY_RS00770
uniprot id: H8WBL5
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS12515
gene id: 1163748:MARHY_RS12515
uniprot id: H8WBA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1163748:MARHY RS10655
gene id: 1163748:MARHY_RS10655
uniprot id: H8W7S7
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS02895
gene id: 1163748:MARHY_RS02895
uniprot id: H8W495
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1163748:MARHY RS11745
gene id: 1163748:MARHY_RS11745
uniprot id: H8W9S5
names: Similarity
messages: Belongs to the Skp family.

1163748:MARHY RS11755
gene id: 1163748:MARHY_RS11755
uniprot id: H8W9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1163748:MARHY RS06570
gene id: 1163748:MARHY_RS06570
uniprot id: H8WB58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1163748:MARHY RS10075
gene id: 1163748:MARHY_RS10075
uniprot id: H8W6I6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1163748:MARHY RS10755
gene id: 1163748:MARHY_RS10755
uniprot id: H8W7U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1163748:MARHY RS06255
gene id: 1163748:MARHY_RS06255
uniprot id: H8WAH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS02450
gene id: 1163748:MARHY_RS02450
uniprot id: H8WEF4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1163748:MARHY RS14665
gene id: 1163748:MARHY_RS14665
uniprot id: H8WEV1
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

1163748:MARHY RS02120
gene id: 1163748:MARHY_RS02120
uniprot id: H8WDR9
names: Similarity
messages: Belongs to the P(II) protein family.

1163748:MARHY RS11740
gene id: 1163748:MARHY_RS11740
uniprot id: H8W9S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1163748:MARHY RS05940
gene id: 1163748:MARHY_RS05940
uniprot id: H8W9Q6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1163748:MARHY RS01805
gene id: 1163748:MARHY_RS01805
uniprot id: H8WDK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1163748:MARHY RS00275
gene id: 1163748:MARHY_RS00275
uniprot id: H8WAV2
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS10430
gene id: 1163748:MARHY_RS10430
uniprot id: H8W768
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS04095
gene id: 1163748:MARHY_RS04095
uniprot id: H8W6C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1163748:MARHY RS01880
gene id: 1163748:MARHY_RS01880
uniprot id: H8WDM0
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1163748:MARHY RS12985
gene id: 1163748:MARHY_RS12985
uniprot id: H8WC07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1163748:MARHY RS11255
gene id: 1163748:MARHY_RS11255
uniprot id: H8W8L2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1163748:MARHY RS00835
gene id: 1163748:MARHY_RS00835
uniprot id: H8WBM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS01360
gene id: 1163748:MARHY_RS01360
uniprot id: H8WCE5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1163748:MARHY RS12705
gene id: 1163748:MARHY_RS12705
uniprot id: H8WBE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1163748:MARHY RS08415
gene id: 1163748:MARHY_RS08415
uniprot id: H8WEJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1163748:MARHY RS15095
gene id: 1163748:MARHY_RS15095
uniprot id: H8W4N4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1163748:MARHY RS00795
gene id: 1163748:MARHY_RS00795
uniprot id: H8WBM0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1163748:MARHY RS11250
gene id: 1163748:MARHY_RS11250
uniprot id: H8W8L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1163748:MARHY RS10065
gene id: 1163748:MARHY_RS10065
uniprot id: H8W6I4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1163748:MARHY RS11375
gene id: 1163748:MARHY_RS11375
uniprot id: H8W948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1163748:MARHY RS10215
gene id: 1163748:MARHY_RS10215
uniprot id: H8W725
names: Similarity
messages: Belongs to the YfgM family.

1163748:MARHY RS03535
gene id: 1163748:MARHY_RS03535
uniprot id: H8W5J8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1163748:MARHY RS10245
gene id: 1163748:MARHY_RS10245
uniprot id: H8W731
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1163748:MARHY RS15815
gene id: 1163748:MARHY_RS15815
uniprot id: H8W604
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1163748:MARHY RS03725
gene id: 1163748:MARHY_RS03725
uniprot id: H8W646
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1163748:MARHY RS12460
gene id: 1163748:MARHY_RS12460
uniprot id: H8WAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1163748:MARHY RS03030
gene id: 1163748:MARHY_RS03030
uniprot id: H8W4T4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1163748:MARHY RS07355
gene id: 1163748:MARHY_RS07355
uniprot id: H8WCJ0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1163748:MARHY RS09325
gene id: 1163748:MARHY_RS09325
uniprot id: H8W561
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1163748:MARHY RS01095
gene id: 1163748:MARHY_RS01095
uniprot id: H8WC91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1163748:MARHY RS12755
gene id: 1163748:MARHY_RS12755
uniprot id: H8WBF1
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1163748:MARHY RS16790
gene id: 1163748:MARHY_RS16790
uniprot id: H8W7Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1163748:MARHY RS12235
gene id: 1163748:MARHY_RS12235
uniprot id: H8WAM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1163748:MARHY RS07515
gene id: 1163748:MARHY_RS07515
uniprot id: H8WCM3
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1163748:MARHY RS11495
gene id: 1163748:MARHY_RS11495
uniprot id: H8W966
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1163748:MARHY RS04960
gene id: 1163748:MARHY_RS04960
uniprot id: H8W879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1163748:MARHY RS06425
gene id: 1163748:MARHY_RS06425
uniprot id: H8WB28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1163748:MARHY RS11075
gene id: 1163748:MARHY_RS11075
uniprot id: H8W8H4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1163748:MARHY RS11225
gene id: 1163748:MARHY_RS11225
uniprot id: H8W8K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1163748:MARHY RS07500
gene id: 1163748:MARHY_RS07500
uniprot id: H8WCM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1163748:MARHY RS09475
gene id: 1163748:MARHY_RS09475
uniprot id: H8W5Q3
names: Similarity
messages: Belongs to the thioredoxin family.

1163748:MARHY RS08815
gene id: 1163748:MARHY_RS08815
uniprot id: H8W4C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1163748:MARHY RS12550
gene id: 1163748:MARHY_RS12550
uniprot id: H8WBA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS05555
gene id: 1163748:MARHY_RS05555
uniprot id: H8W917
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS02485
gene id: 1163748:MARHY_RS02485
uniprot id: H8WEG1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1163748:MARHY RS06600
gene id: 1163748:MARHY_RS06600
uniprot id: H8WB64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

1163748:MARHY RS11070
gene id: 1163748:MARHY_RS11070
uniprot id: H8W8H3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1163748:MARHY RS00035
gene id: 1163748:MARHY_RS00035
uniprot id: H8WA86
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1163748:MARHY RS03645
gene id: 1163748:MARHY_RS03645
uniprot id: H8W5M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1163748:MARHY RS01465
gene id: 1163748:MARHY_RS01465
uniprot id: H8WCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS01535
gene id: 1163748:MARHY_RS01535
uniprot id: H8WCZ2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1163748:MARHY RS02695
gene id: 1163748:MARHY_RS02695
uniprot id: H8W457
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS08260
gene id: 1163748:MARHY_RS08260
uniprot id: H8WDZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1163748:MARHY RS18720
gene id: 1163748:MARHY_RS18720
uniprot id: H8WEK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1163748:MARHY RS11065
gene id: 1163748:MARHY_RS11065
uniprot id: H8W8H2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1163748:MARHY RS01715
gene id: 1163748:MARHY_RS01715
uniprot id: H8WD28
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1163748:MARHY RS00245
gene id: 1163748:MARHY_RS00245
uniprot id: H8WAU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1163748:MARHY RS11945
gene id: 1163748:MARHY_RS11945
uniprot id: H8W9W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1163748:MARHY RS10650
gene id: 1163748:MARHY_RS10650
uniprot id: H8W7S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1163748:MARHY RS02345
gene id: 1163748:MARHY_RS02345
uniprot id: H8WED0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1163748:MARHY RS13460
gene id: 1163748:MARHY_RS13460
uniprot id: H8WCS1
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS10540
gene id: 1163748:MARHY_RS10540
uniprot id: H8W7Q4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1163748:MARHY RS00060
gene id: 1163748:MARHY_RS00060
uniprot id: H8WA91
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1163748:MARHY RS06280
gene id: 1163748:MARHY_RS06280
uniprot id: H8WAH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1163748:MARHY RS07335
gene id: 1163748:MARHY_RS07335
uniprot id: H8WCI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS12520
gene id: 1163748:MARHY_RS12520
uniprot id: H8WBA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1163748:MARHY RS05875
gene id: 1163748:MARHY_RS05875
uniprot id: H8W9N9
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS12000
gene id: 1163748:MARHY_RS12000
uniprot id: H8W9X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1163748:MARHY RS14335
gene id: 1163748:MARHY_RS14335
uniprot id: H8WE76
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1163748:MARHY RS18255
gene id: 1163748:MARHY_RS18255
uniprot id: H8WA71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1163748:MARHY RS03515
gene id: 1163748:MARHY_RS03515
uniprot id: H8W5J4
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1163748:MARHY RS10375
gene id: 1163748:MARHY_RS10375
uniprot id: H8W757
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS14185
gene id: 1163748:MARHY_RS14185
uniprot id: H8WE46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1163748:MARHY RS06585
gene id: 1163748:MARHY_RS06585
uniprot id: H8WB61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1163748:MARHY RS08095
gene id: 1163748:MARHY_RS08095
uniprot id: H8WDW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1163748:MARHY RS09965
gene id: 1163748:MARHY_RS09965
uniprot id: H8W6G4
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1163748:MARHY RS01695
gene id: 1163748:MARHY_RS01695
uniprot id: H8WD24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1163748:MARHY RS15080
gene id: 1163748:MARHY_RS15080
uniprot id: H8W4N1
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1163748:MARHY RS09895
gene id: 1163748:MARHY_RS09895
uniprot id: H8W6E9
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1163748:MARHY RS11960
gene id: 1163748:MARHY_RS11960
uniprot id: H8W9W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1163748:MARHY RS12080
gene id: 1163748:MARHY_RS12080
uniprot id: H8W9Z4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1163748:MARHY RS06575
gene id: 1163748:MARHY_RS06575
uniprot id: H8WB59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1163748:MARHY RS10090
gene id: 1163748:MARHY_RS10090
uniprot id: H8W6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS16905
gene id: 1163748:MARHY_RS16905
uniprot id: H8W811
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163748:MARHY RS16170
gene id: 1163748:MARHY_RS16170
uniprot id: H8W6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

1163748:MARHY RS05510
gene id: 1163748:MARHY_RS05510
uniprot id: H8W908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS11895
gene id: 1163748:MARHY_RS11895
uniprot id: H8W9V5
names: Similarity
messages: Belongs to the VgrG protein family.

1163748:MARHY RS04320
gene id: 1163748:MARHY_RS04320
uniprot id: H8W6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS07445
gene id: 1163748:MARHY_RS07445
uniprot id: H8WCK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1163748:MARHY RS01100
gene id: 1163748:MARHY_RS01100
uniprot id: H8WC92
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS06435
gene id: 1163748:MARHY_RS06435
uniprot id: H8WB30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1163748:MARHY RS02470
gene id: 1163748:MARHY_RS02470
uniprot id: H8WEF8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1163748:MARHY RS08635
gene id: 1163748:MARHY_RS08635
uniprot id: H8WEN7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1163748:MARHY RS10000
gene id: 1163748:MARHY_RS10000
uniprot id: H8W6H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1163748:MARHY RS07090
gene id: 1163748:MARHY_RS07090
uniprot id: H8WBX2
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1163748:MARHY RS15680
gene id: 1163748:MARHY_RS15680
uniprot id: H8W5X6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1163748:MARHY RS07025
gene id: 1163748:MARHY_RS07025
uniprot id: H8WBV8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1163748:MARHY RS08330
gene id: 1163748:MARHY_RS08330
uniprot id: H8WE13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1163748:MARHY RS16070
gene id: 1163748:MARHY_RS16070
uniprot id: H8W6L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163748:MARHY RS10525
gene id: 1163748:MARHY_RS10525
uniprot id: H8W789
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS06250
gene id: 1163748:MARHY_RS06250
uniprot id: H8WAH1
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

1163748:MARHY RS02630
gene id: 1163748:MARHY_RS02630
uniprot id: H8W446
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1163748:MARHY RS07060
gene id: 1163748:MARHY_RS07060
uniprot id: H8WBW6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1163748:MARHY RS11175
gene id: 1163748:MARHY_RS11175
uniprot id: H8W8J6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163748:MARHY RS07825
gene id: 1163748:MARHY_RS07825
uniprot id: H8WD96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1163748:MARHY RS03505
gene id: 1163748:MARHY_RS03505
uniprot id: H8W5J1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1163748:MARHY RS08030
gene id: 1163748:MARHY_RS08030
uniprot id: H8WDV1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1163748:MARHY RS07680
gene id: 1163748:MARHY_RS07680
uniprot id: H8WD66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1163748:MARHY RS04730
gene id: 1163748:MARHY_RS04730
uniprot id: H8W7M1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1163748:MARHY RS07010
gene id: 1163748:MARHY_RS07010
uniprot id: H8WBV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1163748:MARHY RS01610
gene id: 1163748:MARHY_RS01610
uniprot id: H8WD07
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1163748:MARHY RS14650
gene id: 1163748:MARHY_RS14650
uniprot id: H8WEU8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1163748:MARHY RS10285
gene id: 1163748:MARHY_RS10285
uniprot id: H8W739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS16285
gene id: 1163748:MARHY_RS16285
uniprot id: H8W6R3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS15020
gene id: 1163748:MARHY_RS15020
uniprot id: H8W4L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163748:MARHY RS03995
gene id: 1163748:MARHY_RS03995
uniprot id: H8W6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1163748:MARHY RS18195
gene id: 1163748:MARHY_RS18195
uniprot id: H8WA59
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS10700
gene id: 1163748:MARHY_RS10700
uniprot id: H8W7T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1163748:MARHY RS16785
gene id: 1163748:MARHY_RS16785
uniprot id: H8W7Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1163748:MARHY RS05630
gene id: 1163748:MARHY_RS05630
uniprot id: H8W933
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163748:MARHY RS11270
gene id: 1163748:MARHY_RS11270
uniprot id: H8W8L5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1163748:MARHY RS00200
gene id: 1163748:MARHY_RS00200
uniprot id: H8WAB8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1163748:MARHY RS15765
gene id: 1163748:MARHY_RS15765
uniprot id: H8W5Z3
names: Similarity
messages: Belongs to the peptidase M24B family.

1163748:MARHY RS00535
gene id: 1163748:MARHY_RS00535
uniprot id: H8WB08
names: Similarity
messages: Belongs to the YkuD family.

1163748:MARHY RS12480
gene id: 1163748:MARHY_RS12480
uniprot id: H8WAS6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1163748:MARHY RS06975
gene id: 1163748:MARHY_RS06975
uniprot id: H8WBV1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1163748:MARHY RS10550
gene id: 1163748:MARHY_RS10550
uniprot id: H8W7Q6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS06840
gene id: 1163748:MARHY_RS06840
uniprot id: H8WBS4
names: Similarity
messages: Belongs to the peptidase S49 family.

1163748:MARHY RS10690
gene id: 1163748:MARHY_RS10690
uniprot id: H8W7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1163748:MARHY RS00870
gene id: 1163748:MARHY_RS00870
uniprot id: H8WBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1163748:MARHY RS12695
gene id: 1163748:MARHY_RS12695
uniprot id: H8WBD9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1163748:MARHY RS17815
gene id: 1163748:MARHY_RS17815
uniprot id: H8W9G9
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1163748:MARHY RS02240
gene id: 1163748:MARHY_RS02240
uniprot id: H8WEA6
names: Cofactor
messages: Probably binds two magnesium or manganese ions per subunit.

1163748:MARHY RS17380
gene id: 1163748:MARHY_RS17380
uniprot id: H8W8S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1163748:MARHY RS07315
gene id: 1163748:MARHY_RS07315
uniprot id: H8WCI1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1163748:MARHY RS04375
gene id: 1163748:MARHY_RS04375
uniprot id: H8W6Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1163748:MARHY RS17365
gene id: 1163748:MARHY_RS17365
uniprot id: H8W8R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1163748:MARHY RS04245
gene id: 1163748:MARHY_RS04245
uniprot id: H8W6W0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1163748:MARHY RS13095
gene id: 1163748:MARHY_RS13095
uniprot id: H8WC30
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS05250
gene id: 1163748:MARHY_RS05250
uniprot id: H8W8E1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS11545
gene id: 1163748:MARHY_RS11545
uniprot id: H8W976
names: Similarity
messages: Belongs to the histone deacetylase family.

1163748:MARHY RS00360
gene id: 1163748:MARHY_RS00360
uniprot id: H8WAX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163748:MARHY RS17740
gene id: 1163748:MARHY_RS17740
uniprot id: H8W9F4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163748:MARHY RS03975
gene id: 1163748:MARHY_RS03975
uniprot id: H8W696
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1163748:MARHY RS12230
gene id: 1163748:MARHY_RS12230
uniprot id: H8WAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS11725
gene id: 1163748:MARHY_RS11725
uniprot id: H8W9S1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1163748:MARHY RS12930
gene id: 1163748:MARHY_RS12930
uniprot id: H8WBZ5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1163748:MARHY RS13730
gene id: 1163748:MARHY_RS13730
uniprot id: H8WDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1163748:MARHY RS00390
gene id: 1163748:MARHY_RS00390
uniprot id: H8WAX7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1163748:MARHY RS12385
gene id: 1163748:MARHY_RS12385
uniprot id: H8WAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1163748:MARHY RS08375
gene id: 1163748:MARHY_RS08375
uniprot id: H8WEI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1163748:MARHY RS12260
gene id: 1163748:MARHY_RS12260
uniprot id: H8WAN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1163748:MARHY RS07205
gene id: 1163748:MARHY_RS07205
uniprot id: H8WCF8
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS16840
gene id: 1163748:MARHY_RS16840
uniprot id: H8W7Z8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1163748:MARHY RS08385
gene id: 1163748:MARHY_RS08385
uniprot id: H8WEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS11320
gene id: 1163748:MARHY_RS11320
uniprot id: H8W937
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1163748:MARHY RS06235
gene id: 1163748:MARHY_RS06235
uniprot id: H8WAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1163748:MARHY RS01990
gene id: 1163748:MARHY_RS01990
uniprot id: H8WDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1163748:MARHY RS07410
gene id: 1163748:MARHY_RS07410
uniprot id: H8WCK1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1163748:MARHY RS17805
gene id: 1163748:MARHY_RS17805
uniprot id: H8W9G7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS11915
gene id: 1163748:MARHY_RS11915
uniprot id: H8W9V9
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1163748:MARHY RS14750
gene id: 1163748:MARHY_RS14750
uniprot id: H8WEW8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1163748:MARHY RS09155
gene id: 1163748:MARHY_RS09155
uniprot id: H8W520
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1163748:MARHY RS15285
gene id: 1163748:MARHY_RS15285
uniprot id: H8W583
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1163748:MARHY RS06985
gene id: 1163748:MARHY_RS06985
uniprot id: H8WBV3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS02735
gene id: 1163748:MARHY_RS02735
uniprot id: H8W461
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS09600
gene id: 1163748:MARHY_RS09600
uniprot id: H8W5S9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS06855
gene id: 1163748:MARHY_RS06855
uniprot id: H8WBS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1163748:MARHY RS06730
gene id: 1163748:MARHY_RS06730
uniprot id: H8WB91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS13575
gene id: 1163748:MARHY_RS13575
uniprot id: H8WCU4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1163748:MARHY RS16985
gene id: 1163748:MARHY_RS16985
uniprot id: H8W828
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1163748:MARHY RS14865
gene id: 1163748:MARHY_RS14865
uniprot id: H8W4I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1163748:MARHY RS15855
gene id: 1163748:MARHY_RS15855
uniprot id: H8W614
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1163748:MARHY RS11720
gene id: 1163748:MARHY_RS11720
uniprot id: H8W9S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1163748:MARHY RS03690
gene id: 1163748:MARHY_RS03690
uniprot id: H8W5M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1163748:MARHY RS12805
gene id: 1163748:MARHY_RS12805
uniprot id: H8WBG1
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS07165
gene id: 1163748:MARHY_RS07165
uniprot id: H8WBY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1163748:MARHY RS10350
gene id: 1163748:MARHY_RS10350
uniprot id: H8W752
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1163748:MARHY RS05725
gene id: 1163748:MARHY_RS05725
uniprot id: H8W9K8
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS11940
gene id: 1163748:MARHY_RS11940
uniprot id: H8W9W4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1163748:MARHY RS07405
gene id: 1163748:MARHY_RS07405
uniprot id: H8WCK0
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1163748:MARHY RS10495
gene id: 1163748:MARHY_RS10495
uniprot id: H8W782
names: Similarity
messages: Belongs to the nitroreductase family.

1163748:MARHY RS08245
gene id: 1163748:MARHY_RS08245
uniprot id: H8WDZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1163748:MARHY RS01135
gene id: 1163748:MARHY_RS01135
uniprot id: H8WC99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1163748:MARHY RS05910
gene id: 1163748:MARHY_RS05910
uniprot id: H8W9P9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1163748:MARHY RS15225
gene id: 1163748:MARHY_RS15225
uniprot id: H8W4R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1163748:MARHY RS13785
gene id: 1163748:MARHY_RS13785
uniprot id: H8WDE9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1163748:MARHY RS07805
gene id: 1163748:MARHY_RS07805
uniprot id: H8WD92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1163748:MARHY RS12715
gene id: 1163748:MARHY_RS12715
uniprot id: H8WBE3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS10110
gene id: 1163748:MARHY_RS10110
uniprot id: H8W6J4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1163748:MARHY RS13130
gene id: 1163748:MARHY_RS13130
uniprot id: H8WC37
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS11050
gene id: 1163748:MARHY_RS11050
uniprot id: H8W8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1163748:MARHY RS04765
gene id: 1163748:MARHY_RS04765
uniprot id: H8W7M8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS04455
gene id: 1163748:MARHY_RS04455
uniprot id: H8W702
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1163748:MARHY RS03100
gene id: 1163748:MARHY_RS03100
uniprot id: H8W4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS04690
gene id: 1163748:MARHY_RS04690
uniprot id: H8W7L3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163748:MARHY RS04890
gene id: 1163748:MARHY_RS04890
uniprot id: H8W864
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS06400
gene id: 1163748:MARHY_RS06400
uniprot id: H8WAK1
names: Similarity
messages: Belongs to the GSP E family.

1163748:MARHY RS03290
gene id: 1163748:MARHY_RS03290
uniprot id: H8W4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1163748:MARHY RS11790
gene id: 1163748:MARHY_RS11790
uniprot id: H8W9T4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1163748:MARHY RS17375
gene id: 1163748:MARHY_RS17375
uniprot id: H8W8R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1163748:MARHY RS18315
gene id: 1163748:MARHY_RS18315
uniprot id: H8WAT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1163748:MARHY RS16075
gene id: 1163748:MARHY_RS16075
uniprot id: H8W6M0
names: Similarity
messages: Belongs to the CFA/CMAS family.

1163748:MARHY RS09665
gene id: 1163748:MARHY_RS09665
uniprot id: H8W5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS04505
gene id: 1163748:MARHY_RS04505
uniprot id: H8W7H2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1163748:MARHY RS16955
gene id: 1163748:MARHY_RS16955
uniprot id: H8W821
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1163748:MARHY RS07030
gene id: 1163748:MARHY_RS07030
uniprot id: H8WBV9
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

1163748:MARHY RS11295
gene id: 1163748:MARHY_RS11295
uniprot id: H8W8M0
names: Similarity
messages: Belongs to the WrbA family.

1163748:MARHY RS02755
gene id: 1163748:MARHY_RS02755
uniprot id: H8W465
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1163748:MARHY RS10305
gene id: 1163748:MARHY_RS10305
uniprot id: H8W742
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1163748:MARHY RS02940
gene id: 1163748:MARHY_RS02940
uniprot id: H8W4R5
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1163748:MARHY RS04930
gene id: 1163748:MARHY_RS04930
uniprot id: H8W872
names: Similarity
messages: Belongs to the peptidase S13 family.

1163748:MARHY RS11290
gene id: 1163748:MARHY_RS11290
uniprot id: H8W8L9
names: Similarity
messages: Belongs to the ArsC family.

1163748:MARHY RS00945
gene id: 1163748:MARHY_RS00945
uniprot id: H8WBQ2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1163748:MARHY RS08495
gene id: 1163748:MARHY_RS08495
uniprot id: H8WEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1163748:MARHY RS03740
gene id: 1163748:MARHY_RS03740
uniprot id: H8W649
names: Similarity
messages: Belongs to the UPF0102 family.

1163748:MARHY RS12610
gene id: 1163748:MARHY_RS12610
uniprot id: H8WBC2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1163748:MARHY RS06850
gene id: 1163748:MARHY_RS06850
uniprot id: H8WBS6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1163748:MARHY RS15790
gene id: 1163748:MARHY_RS15790
uniprot id: H8W5Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1163748:MARHY RS10380
gene id: 1163748:MARHY_RS10380
uniprot id: H8W758
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS06870
gene id: 1163748:MARHY_RS06870
uniprot id: H8WBT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1163748:MARHY RS15615
gene id: 1163748:MARHY_RS15615
uniprot id: H8W5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS02910
gene id: 1163748:MARHY_RS02910
uniprot id: H8W499
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1163748:MARHY RS03855
gene id: 1163748:MARHY_RS03855
uniprot id: H8W672
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1163748:MARHY RS03490
gene id: 1163748:MARHY_RS03490
uniprot id: H8W5I8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1163748:MARHY RS15115
gene id: 1163748:MARHY_RS15115
uniprot id: H8W4N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1163748:MARHY RS01900
gene id: 1163748:MARHY_RS01900
uniprot id: H8WDM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1163748:MARHY RS13865
gene id: 1163748:MARHY_RS13865
uniprot id: H8WDG5
names: Similarity
messages: Belongs to the thioredoxin family.

1163748:MARHY RS08810
gene id: 1163748:MARHY_RS08810
uniprot id: H8W4C3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1163748:MARHY RS04555
gene id: 1163748:MARHY_RS04555
uniprot id: H8W7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1163748:MARHY RS06310
gene id: 1163748:MARHY_RS06310
uniprot id: H8WAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1163748:MARHY RS12570
gene id: 1163748:MARHY_RS12570
uniprot id: H8WBB4
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1163748:MARHY RS06505
gene id: 1163748:MARHY_RS06505
uniprot id: H8WB45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1163748:MARHY RS03420
gene id: 1163748:MARHY_RS03420
uniprot id: H8W5H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1163748:MARHY RS02525
gene id: 1163748:MARHY_RS02525
uniprot id: H8WEG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1163748:MARHY RS04210
gene id: 1163748:MARHY_RS04210
uniprot id: H8W6V3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1163748:MARHY RS05915
gene id: 1163748:MARHY_RS05915
uniprot id: H8W9Q0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1163748:MARHY RS15865
gene id: 1163748:MARHY_RS15865
uniprot id: H8W616
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1163748:MARHY RS02255
gene id: 1163748:MARHY_RS02255
uniprot id: H8WEA9
names: Similarity
messages: Belongs to the universal stress protein A family.

1163748:MARHY RS00880
gene id: 1163748:MARHY_RS00880
uniprot id: H8WBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163748:MARHY RS09300
gene id: 1163748:MARHY_RS09300
uniprot id: H8W555
names: Similarity
messages: Belongs to the thioredoxin family.

1163748:MARHY RS06330
gene id: 1163748:MARHY_RS06330
uniprot id: H8WAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1163748:MARHY RS10280
gene id: 1163748:MARHY_RS10280
uniprot id: H8W738
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1163748:MARHY RS12995
gene id: 1163748:MARHY_RS12995
uniprot id: H8WC09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1163748:MARHY RS05050
gene id: 1163748:MARHY_RS05050
uniprot id: H8W8A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1163748:MARHY RS12620
gene id: 1163748:MARHY_RS12620
uniprot id: H8WBC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1163748:MARHY RS03065
gene id: 1163748:MARHY_RS03065
uniprot id: H8W4U2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1163748:MARHY RS15050
gene id: 1163748:MARHY_RS15050
uniprot id: H8W4M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1163748:MARHY RS11485
gene id: 1163748:MARHY_RS11485
uniprot id: H8W964
names: Similarity
messages: Belongs to the peptidase S41A family.

1163748:MARHY RS01770
gene id: 1163748:MARHY_RS01770
uniprot id: H8WD38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1163748:MARHY RS15205
gene id: 1163748:MARHY_RS15205
uniprot id: H8W4Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1163748:MARHY RS14265
gene id: 1163748:MARHY_RS14265
uniprot id: H8WE62
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS16825
gene id: 1163748:MARHY_RS16825
uniprot id: H8W7Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS17355
gene id: 1163748:MARHY_RS17355
uniprot id: H8W8R5
names: Similarity
messages: Belongs to the hyi family.

1163748:MARHY RS10780
gene id: 1163748:MARHY_RS10780
uniprot id: H8W7V3
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS00865
gene id: 1163748:MARHY_RS00865
uniprot id: H8WBN6
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS16665
gene id: 1163748:MARHY_RS16665
uniprot id: H8W7F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1163748:MARHY RS00460
gene id: 1163748:MARHY_RS00460
uniprot id: H8WAZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1163748:MARHY RS03050
gene id: 1163748:MARHY_RS03050
uniprot id: H8W4T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1163748:MARHY RS15065
gene id: 1163748:MARHY_RS15065
uniprot id: H8W4M8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163748:MARHY RS01945
gene id: 1163748:MARHY_RS01945
uniprot id: H8WDN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1163748:MARHY RS02845
gene id: 1163748:MARHY_RS02845
uniprot id: H8W484
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1163748:MARHY RS18250
gene id: 1163748:MARHY_RS18250
uniprot id: H8WA70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1163748:MARHY RS04055
gene id: 1163748:MARHY_RS04055
uniprot id: H8W6B3
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1163748:MARHY RS18330
gene id: 1163748:MARHY_RS18330
uniprot id: H8WAT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1163748:MARHY RS12785
gene id: 1163748:MARHY_RS12785
uniprot id: H8WBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS10015
gene id: 1163748:MARHY_RS10015
uniprot id: H8W6H4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS14220
gene id: 1163748:MARHY_RS14220
uniprot id: H8WE53
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1163748:MARHY RS12895
gene id: 1163748:MARHY_RS12895
uniprot id: H8WBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1163748:MARHY RS11120
gene id: 1163748:MARHY_RS11120
uniprot id: H8W8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1163748:MARHY RS15335
gene id: 1163748:MARHY_RS15335
uniprot id: H8W593
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1163748:MARHY RS12670
gene id: 1163748:MARHY_RS12670
uniprot id: H8WBD4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1163748:MARHY RS10225
gene id: 1163748:MARHY_RS10225
uniprot id: H8W727
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1163748:MARHY RS08390
gene id: 1163748:MARHY_RS08390
uniprot id: H8WEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS04845
gene id: 1163748:MARHY_RS04845
uniprot id: H8W7P5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1163748:MARHY RS10625
gene id: 1163748:MARHY_RS10625
uniprot id: H8W7S1
names: Similarity
messages: Belongs to the peptidase M18 family.

1163748:MARHY RS02890
gene id: 1163748:MARHY_RS02890
uniprot id: H8W494
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1163748:MARHY RS03770
gene id: 1163748:MARHY_RS03770
uniprot id: H8W655
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1163748:MARHY RS11815
gene id: 1163748:MARHY_RS11815
uniprot id: H8W9T9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS02935
gene id: 1163748:MARHY_RS02935
uniprot id: H8W4R4
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS07275
gene id: 1163748:MARHY_RS07275
uniprot id: H8WCH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1163748:MARHY RS04705
gene id: 1163748:MARHY_RS04705
uniprot id: H8W7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1163748:MARHY RS04195
gene id: 1163748:MARHY_RS04195
uniprot id: H8W6V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1163748:MARHY RS11235
gene id: 1163748:MARHY_RS11235
uniprot id: H8W8K8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1163748:MARHY RS07620
gene id: 1163748:MARHY_RS07620
uniprot id: H8WD56
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1163748:MARHY RS17920
gene id: 1163748:MARHY_RS17920
uniprot id: H8W9Z9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1163748:MARHY RS14780
gene id: 1163748:MARHY_RS14780
uniprot id: H8WEX4
names: Similarity
messages: Belongs to the SufE family.

1163748:MARHY RS15400
gene id: 1163748:MARHY_RS15400
uniprot id: H8W5B2
names: Similarity
messages: Belongs to the MQO family.

1163748:MARHY RS03445
gene id: 1163748:MARHY_RS03445
uniprot id: H8W5I0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1163748:MARHY RS04725
gene id: 1163748:MARHY_RS04725
uniprot id: H8W7M0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1163748:MARHY RS18235
gene id: 1163748:MARHY_RS18235
uniprot id: H8WA67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1163748:MARHY RS11735
gene id: 1163748:MARHY_RS11735
uniprot id: H8W9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1163748:MARHY RS00255
gene id: 1163748:MARHY_RS00255
uniprot id: H8WAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS03760
gene id: 1163748:MARHY_RS03760
uniprot id: H8W653
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1163748:MARHY RS12325
gene id: 1163748:MARHY_RS12325
uniprot id: H8WAP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1163748:MARHY RS07045
gene id: 1163748:MARHY_RS07045
uniprot id: H8WBW3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS02135
gene id: 1163748:MARHY_RS02135
uniprot id: H8WDS3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS16890
gene id: 1163748:MARHY_RS16890
uniprot id: H8W808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS15255
gene id: 1163748:MARHY_RS15255
uniprot id: H8W577
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1163748:MARHY RS16610
gene id: 1163748:MARHY_RS16610
uniprot id: H8W7D9
names: Similarity
messages: Belongs to the group II decarboxylase family.

1163748:MARHY RS02310
gene id: 1163748:MARHY_RS02310
uniprot id: H8WEC0
names: Disruption Phenotype
names: Function
names: Induction
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Expression increases during biofilm formation on n-hexadecane. Forms an operon with aupA.
messages: Interacts with the outer membrane protein AupA.
messages: Mutants show a lower rate of biofilm formation on solid paraffin and on the liquid alkane n-hexadecane, while growth on nonalkane substrates was not affected. Planktonic growth on water-soluble substrates is not affected. Mutants are impaired in the assimilation of n-hexadecane solubilized in surfactant micelles.
messages: Required for growth on alkanes. Probably involved in the uptake of micelle-solubilized alkanes. May facilitate the transfer of alkanes from the outer membrane to the inner membrane.

1163748:MARHY RS16415
gene id: 1163748:MARHY_RS16415
uniprot id: H8W797
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1163748:MARHY RS05080
gene id: 1163748:MARHY_RS05080
uniprot id: H8W8A6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1163748:MARHY RS12600
gene id: 1163748:MARHY_RS12600
uniprot id: H8WBC0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1163748:MARHY RS09215
gene id: 1163748:MARHY_RS09215
uniprot id: H8W535
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1163748:MARHY RS18180
gene id: 1163748:MARHY_RS18180
uniprot id: H8WA56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1163748:MARHY RS07600
gene id: 1163748:MARHY_RS07600
uniprot id: H8WD52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS06710
gene id: 1163748:MARHY_RS06710
uniprot id: H8WB86
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1163748:MARHY RS07700
gene id: 1163748:MARHY_RS07700
uniprot id: H8WD70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1163748:MARHY RS09730
gene id: 1163748:MARHY_RS09730
uniprot id: H8W5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1163748:MARHY RS08325
gene id: 1163748:MARHY_RS08325
uniprot id: H8WE12
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS13580
gene id: 1163748:MARHY_RS13580
uniprot id: H8WCU5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1163748:MARHY RS02795
gene id: 1163748:MARHY_RS02795
uniprot id: H8W474
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1163748:MARHY RS17745
gene id: 1163748:MARHY_RS17745
uniprot id: H8W9F5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1163748:MARHY RS11920
gene id: 1163748:MARHY_RS11920
uniprot id: H8W9W0
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS13180
gene id: 1163748:MARHY_RS13180
uniprot id: H8WC47
names: Similarity
messages: Belongs to the IMPACT family.

1163748:MARHY RS14380
gene id: 1163748:MARHY_RS14380
uniprot id: H8WE85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1163748:MARHY RS02165
gene id: 1163748:MARHY_RS02165
uniprot id: H8WDS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1163748:MARHY RS03225
gene id: 1163748:MARHY_RS03225
uniprot id: H8W4X4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1163748:MARHY RS13630
gene id: 1163748:MARHY_RS13630
uniprot id: H8WCV8
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS06135
gene id: 1163748:MARHY_RS06135
uniprot id: H8WAE7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1163748:MARHY RS09165
gene id: 1163748:MARHY_RS09165
uniprot id: H8W522
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1163748:MARHY RS12540
gene id: 1163748:MARHY_RS12540
uniprot id: H8WBA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1163748:MARHY RS12020
gene id: 1163748:MARHY_RS12020
uniprot id: H8W9Y1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1163748:MARHY RS03620
gene id: 1163748:MARHY_RS03620
uniprot id: H8W5L6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1163748:MARHY RS16065
gene id: 1163748:MARHY_RS16065
uniprot id: H8W6L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163748:MARHY RS02495
gene id: 1163748:MARHY_RS02495
uniprot id: H8WEG3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1163748:MARHY RS10240
gene id: 1163748:MARHY_RS10240
uniprot id: H8W730
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1163748:MARHY RS15310
gene id: 1163748:MARHY_RS15310
uniprot id: H8W588
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS06620
gene id: 1163748:MARHY_RS06620
uniprot id: H8WB68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1163748:MARHY RS10995
gene id: 1163748:MARHY_RS10995
uniprot id: H8W8G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1163748:MARHY RS11770
gene id: 1163748:MARHY_RS11770
uniprot id: H8W9T0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS15825
gene id: 1163748:MARHY_RS15825
uniprot id: H8W606
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS12005
gene id: 1163748:MARHY_RS12005
uniprot id: H8W9X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1163748:MARHY RS05950
gene id: 1163748:MARHY_RS05950
uniprot id: H8W9Q8
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1163748:MARHY RS01595
gene id: 1163748:MARHY_RS01595
uniprot id: H8WD04
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1163748:MARHY RS15520
gene id: 1163748:MARHY_RS15520
uniprot id: H8W5D7
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1163748:MARHY RS13125
gene id: 1163748:MARHY_RS13125
uniprot id: H8WC36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1163748:MARHY RS03700
gene id: 1163748:MARHY_RS03700
uniprot id: H8W5M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1163748:MARHY RS02825
gene id: 1163748:MARHY_RS02825
uniprot id: H8W480
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1163748:MARHY RS06875
gene id: 1163748:MARHY_RS06875
uniprot id: H8WBT1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1163748:MARHY RS02475
gene id: 1163748:MARHY_RS02475
uniprot id: H8WEF9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1163748:MARHY RS10250
gene id: 1163748:MARHY_RS10250
uniprot id: H8W732
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1163748:MARHY RS03800
gene id: 1163748:MARHY_RS03800
uniprot id: H8W661
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1163748:MARHY RS09795
gene id: 1163748:MARHY_RS09795
uniprot id: H8W6C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS07375
gene id: 1163748:MARHY_RS07375
uniprot id: H8WCJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS02275
gene id: 1163748:MARHY_RS02275
uniprot id: H8WEB3
names: Similarity
messages: Belongs to the RutC family.

1163748:MARHY RS13635
gene id: 1163748:MARHY_RS13635
uniprot id: H8WCV9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1163748:MARHY RS13960
gene id: 1163748:MARHY_RS13960
uniprot id: H8WDI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1163748:MARHY RS12485
gene id: 1163748:MARHY_RS12485
uniprot id: H8WAS7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS07020
gene id: 1163748:MARHY_RS07020
uniprot id: H8WBV6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1163748:MARHY RS06715
gene id: 1163748:MARHY_RS06715
uniprot id: H8WB87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1163748:MARHY RS02095
gene id: 1163748:MARHY_RS02095
uniprot id: H8WDR4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1163748:MARHY RS09505
gene id: 1163748:MARHY_RS09505
uniprot id: H8W5Q9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1163748:MARHY RS05670
gene id: 1163748:MARHY_RS05670
uniprot id: H8W9J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1163748:MARHY RS12330
gene id: 1163748:MARHY_RS12330
uniprot id: H8WAP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1163748:MARHY RS12615
gene id: 1163748:MARHY_RS12615
uniprot id: H8WBC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1163748:MARHY RS09670
gene id: 1163748:MARHY_RS09670
uniprot id: H8W5U3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1163748:MARHY RS01895
gene id: 1163748:MARHY_RS01895
uniprot id: H8WDM3
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1163748:MARHY RS15175
gene id: 1163748:MARHY_RS15175
uniprot id: H8W4Q0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1163748:MARHY RS17410
gene id: 1163748:MARHY_RS17410
uniprot id: H8W8S6
names: Similarity
messages: Belongs to the HSP15 family.

1163748:MARHY RS06885
gene id: 1163748:MARHY_RS06885
uniprot id: H8WBT3
names: Subunit
messages: Homodimer.

1163748:MARHY RS06370
gene id: 1163748:MARHY_RS06370
uniprot id: H8WAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1163748:MARHY RS04735
gene id: 1163748:MARHY_RS04735
uniprot id: H8W7M2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1163748:MARHY RS09255
gene id: 1163748:MARHY_RS09255
uniprot id: H8W544
names: Similarity
messages: Belongs to the pirin family.

1163748:MARHY RS13985
gene id: 1163748:MARHY_RS13985
uniprot id: H8WDJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1163748:MARHY RS17100
gene id: 1163748:MARHY_RS17100
uniprot id: H8W852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1163748:MARHY RS13690
gene id: 1163748:MARHY_RS13690
uniprot id: H8WDC9
names: Similarity
messages: Belongs to the peptidase C56 family.

1163748:MARHY RS04830
gene id: 1163748:MARHY_RS04830
uniprot id: H8W7P1
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1163748:MARHY RS03295
gene id: 1163748:MARHY_RS03295
uniprot id: H8W4Y8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS16830
gene id: 1163748:MARHY_RS16830
uniprot id: H8W7Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1163748:MARHY RS12070
gene id: 1163748:MARHY_RS12070
uniprot id: H8W9Z2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1163748:MARHY RS01260
gene id: 1163748:MARHY_RS01260
uniprot id: H8WCC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1163748:MARHY RS17435
gene id: 1163748:MARHY_RS17435
uniprot id: H8W8T2
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

1163748:MARHY RS16110
gene id: 1163748:MARHY_RS16110
uniprot id: H8W6M7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1163748:MARHY RS17420
gene id: 1163748:MARHY_RS17420
uniprot id: H8W8S8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS17000
gene id: 1163748:MARHY_RS17000
uniprot id: H8W831
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1163748:MARHY RS04090
gene id: 1163748:MARHY_RS04090
uniprot id: H8W6C0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1163748:MARHY RS15610
gene id: 1163748:MARHY_RS15610
uniprot id: H8W5F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS01430
gene id: 1163748:MARHY_RS01430
uniprot id: H8WCX1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS01505
gene id: 1163748:MARHY_RS01505
uniprot id: H8WCY6
names: Similarity
messages: Belongs to the universal stress protein A family.

1163748:MARHY RS05590
gene id: 1163748:MARHY_RS05590
uniprot id: H8W924
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS12905
gene id: 1163748:MARHY_RS12905
uniprot id: H8WBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS13725
gene id: 1163748:MARHY_RS13725
uniprot id: H8WDD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS04135
gene id: 1163748:MARHY_RS04135
uniprot id: H8W6T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1163748:MARHY RS04115
gene id: 1163748:MARHY_RS04115
uniprot id: H8W6T4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1163748:MARHY RS15480
gene id: 1163748:MARHY_RS15480
uniprot id: H8W5C9
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS06335
gene id: 1163748:MARHY_RS06335
uniprot id: H8WAI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1163748:MARHY RS00170
gene id: 1163748:MARHY_RS00170
uniprot id: H8WAB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1163748:MARHY RS05275
gene id: 1163748:MARHY_RS05275
uniprot id: H8W8V6
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1163748:MARHY RS15745
gene id: 1163748:MARHY_RS15745
uniprot id: H8W5Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1163748:MARHY RS03710
gene id: 1163748:MARHY_RS03710
uniprot id: H8W5N1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1163748:MARHY RS17825
gene id: 1163748:MARHY_RS17825
uniprot id: H8W9H1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1163748:MARHY RS08485
gene id: 1163748:MARHY_RS08485
uniprot id: H8WEK7
names: Similarity
messages: Belongs to the DsrF/TusC family.

1163748:MARHY RS09790
gene id: 1163748:MARHY_RS09790
uniprot id: H8W6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1163748:MARHY RS03305
gene id: 1163748:MARHY_RS03305
uniprot id: H8W4Z0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1163748:MARHY RS09150
gene id: 1163748:MARHY_RS09150
uniprot id: H8W519
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS04550
gene id: 1163748:MARHY_RS04550
uniprot id: H8W7I1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS05775
gene id: 1163748:MARHY_RS05775
uniprot id: H8W9L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1163748:MARHY RS13455
gene id: 1163748:MARHY_RS13455
uniprot id: H8WCS0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1163748:MARHY RS09640
gene id: 1163748:MARHY_RS09640
uniprot id: H8W5T7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1163748:MARHY RS01350
gene id: 1163748:MARHY_RS01350
uniprot id: H8WCE3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1163748:MARHY RS14735
gene id: 1163748:MARHY_RS14735
uniprot id: H8WEW5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1163748:MARHY RS02150
gene id: 1163748:MARHY_RS02150
uniprot id: H8WDS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1163748:MARHY RS06325
gene id: 1163748:MARHY_RS06325
uniprot id: H8WAI6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1163748:MARHY RS14215
gene id: 1163748:MARHY_RS14215
uniprot id: H8WE52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1163748:MARHY RS02145
gene id: 1163748:MARHY_RS02145
uniprot id: H8WDS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1163748:MARHY RS15045
gene id: 1163748:MARHY_RS15045
uniprot id: H8W4M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1163748:MARHY RS08590
gene id: 1163748:MARHY_RS08590
uniprot id: H8WEM8
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS14330
gene id: 1163748:MARHY_RS14330
uniprot id: H8WE75
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS04185
gene id: 1163748:MARHY_RS04185
uniprot id: H8W6U9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1163748:MARHY RS16675
gene id: 1163748:MARHY_RS16675
uniprot id: H8W7F2
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1163748:MARHY RS09270
gene id: 1163748:MARHY_RS09270
uniprot id: H8W547
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1163748:MARHY RS13375
gene id: 1163748:MARHY_RS13375
uniprot id: H8WCQ1
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS09565
gene id: 1163748:MARHY_RS09565
uniprot id: H8W5S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1163748:MARHY RS02590
gene id: 1163748:MARHY_RS02590
uniprot id: H8W438
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS17085
gene id: 1163748:MARHY_RS17085
uniprot id: H8W849
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS00500
gene id: 1163748:MARHY_RS00500
uniprot id: H8WB00
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS12720
gene id: 1163748:MARHY_RS12720
uniprot id: H8WBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1163748:MARHY RS02905
gene id: 1163748:MARHY_RS02905
uniprot id: H8W498
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1163748:MARHY RS07480
gene id: 1163748:MARHY_RS07480
uniprot id: H8WCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1163748:MARHY RS16370
gene id: 1163748:MARHY_RS16370
uniprot id: H8W6T1
names: Similarity
messages: Belongs to the GST superfamily.

1163748:MARHY RS10310
gene id: 1163748:MARHY_RS10310
uniprot id: H8W743
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1163748:MARHY RS01175
gene id: 1163748:MARHY_RS01175
uniprot id: H8WCA7
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS08820
gene id: 1163748:MARHY_RS08820
uniprot id: H8W4C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1163748:MARHY RS15885
gene id: 1163748:MARHY_RS15885
uniprot id: H8W620
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1163748:MARHY RS04290
gene id: 1163748:MARHY_RS04290
uniprot id: H8W6W9
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS13235
gene id: 1163748:MARHY_RS13235
uniprot id: H8WC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1163748:MARHY RS06375
gene id: 1163748:MARHY_RS06375
uniprot id: H8WAJ6
names: Similarity
messages: Belongs to the MotB family.

1163748:MARHY RS10315
gene id: 1163748:MARHY_RS10315
uniprot id: H8W744
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1163748:MARHY RS07795
gene id: 1163748:MARHY_RS07795
uniprot id: H8WD89
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1163748:MARHY RS03625
gene id: 1163748:MARHY_RS03625
uniprot id: H8W5L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1163748:MARHY RS11245
gene id: 1163748:MARHY_RS11245
uniprot id: H8W8L0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1163748:MARHY RS03845
gene id: 1163748:MARHY_RS03845
uniprot id: H8W670
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1163748:MARHY RS06540
gene id: 1163748:MARHY_RS06540
uniprot id: H8WB52
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS03705
gene id: 1163748:MARHY_RS03705
uniprot id: H8W5N0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1163748:MARHY RS12605
gene id: 1163748:MARHY_RS12605
uniprot id: H8WBC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS03300
gene id: 1163748:MARHY_RS03300
uniprot id: H8W4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1163748:MARHY RS05535
gene id: 1163748:MARHY_RS05535
uniprot id: H8W913
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1163748:MARHY RS10345
gene id: 1163748:MARHY_RS10345
uniprot id: H8W751
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1163748:MARHY RS06075
gene id: 1163748:MARHY_RS06075
uniprot id: H8WAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1163748:MARHY RS06845
gene id: 1163748:MARHY_RS06845
uniprot id: H8WBS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1163748:MARHY RS00025
gene id: 1163748:MARHY_RS00025
uniprot id: H8WA84
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1163748:MARHY RS16765
gene id: 1163748:MARHY_RS16765
uniprot id: H8W7Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1163748:MARHY RS10795
gene id: 1163748:MARHY_RS10795
uniprot id: H8W7V6
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS05790
gene id: 1163748:MARHY_RS05790
uniprot id: H8W9M1
names: Similarity
messages: Belongs to the peptidase S16 family.

1163748:MARHY RS15040
gene id: 1163748:MARHY_RS15040
uniprot id: H8W4M3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1163748:MARHY RS08310
gene id: 1163748:MARHY_RS08310
uniprot id: H8WE09
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1163748:MARHY RS07625
gene id: 1163748:MARHY_RS07625
uniprot id: H8WD57
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1163748:MARHY RS09805
gene id: 1163748:MARHY_RS09805
uniprot id: H8W6D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1163748:MARHY RS00110
gene id: 1163748:MARHY_RS00110
uniprot id: H8WAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1163748:MARHY RS13990
gene id: 1163748:MARHY_RS13990
uniprot id: H8WDJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1163748:MARHY RS14855
gene id: 1163748:MARHY_RS14855
uniprot id: H8W4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1163748:MARHY RS04140
gene id: 1163748:MARHY_RS04140
uniprot id: H8W6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1163748:MARHY RS01015
gene id: 1163748:MARHY_RS01015
uniprot id: H8WC74
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1163748:MARHY RS15740
gene id: 1163748:MARHY_RS15740
uniprot id: H8W5Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1163748:MARHY RS17935
gene id: 1163748:MARHY_RS17935
uniprot id: H8WA03
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1163748:MARHY RS04060
gene id: 1163748:MARHY_RS04060
uniprot id: H8W6B4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS12130
gene id: 1163748:MARHY_RS12130
uniprot id: H8WAK7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1163748:MARHY RS17660
gene id: 1163748:MARHY_RS17660
uniprot id: H8W9D6
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1163748:MARHY RS05825
gene id: 1163748:MARHY_RS05825
uniprot id: H8W9M8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1163748:MARHY RS04940
gene id: 1163748:MARHY_RS04940
uniprot id: H8W875
names: Similarity
messages: Belongs to the Gfa family.

1163748:MARHY RS03815
gene id: 1163748:MARHY_RS03815
uniprot id: H8W664
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1163748:MARHY RS05585
gene id: 1163748:MARHY_RS05585
uniprot id: H8W923
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1163748:MARHY RS10705
gene id: 1163748:MARHY_RS10705
uniprot id: H8W7T8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1163748:MARHY RS04390
gene id: 1163748:MARHY_RS04390
uniprot id: H8W6Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1163748:MARHY RS12530
gene id: 1163748:MARHY_RS12530
uniprot id: H8WBA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1163748:MARHY RS04980
gene id: 1163748:MARHY_RS04980
uniprot id: H8W883
names: Similarity
messages: Belongs to the UPF0178 family.

1163748:MARHY RS08335
gene id: 1163748:MARHY_RS08335
uniprot id: H8WE14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1163748:MARHY RS06795
gene id: 1163748:MARHY_RS06795
uniprot id: H8WBR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1163748:MARHY RS05545
gene id: 1163748:MARHY_RS05545
uniprot id: H8W915
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1163748:MARHY RS07830
gene id: 1163748:MARHY_RS07830
uniprot id: H8WD97
names: Similarity
messages: Belongs to the citrate synthase family.

1163748:MARHY RS07590
gene id: 1163748:MARHY_RS07590
uniprot id: H8WD50
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1163748:MARHY RS09510
gene id: 1163748:MARHY_RS09510
uniprot id: H8W5R0
names: Similarity
messages: Belongs to the pirin family.

1163748:MARHY RS05215
gene id: 1163748:MARHY_RS05215
uniprot id: H8W8D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1163748:MARHY RS03235
gene id: 1163748:MARHY_RS03235
uniprot id: H8W4X6
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1163748:MARHY RS11210
gene id: 1163748:MARHY_RS11210
uniprot id: H8W8K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1163748:MARHY RS13245
gene id: 1163748:MARHY_RS13245
uniprot id: H8WC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1163748:MARHY RS06665
gene id: 1163748:MARHY_RS06665
uniprot id: H8WB77
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1163748:MARHY RS09230
gene id: 1163748:MARHY_RS09230
uniprot id: H8W538
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS01915
gene id: 1163748:MARHY_RS01915
uniprot id: H8WDM7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1163748:MARHY RS07340
gene id: 1163748:MARHY_RS07340
uniprot id: H8WCI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS10560
gene id: 1163748:MARHY_RS10560
uniprot id: H8W7Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1163748:MARHY RS01870
gene id: 1163748:MARHY_RS01870
uniprot id: H8WDL8
names: Similarity
messages: Belongs to the thioredoxin family.

1163748:MARHY RS12320
gene id: 1163748:MARHY_RS12320
uniprot id: H8WAP5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1163748:MARHY RS06095
gene id: 1163748:MARHY_RS06095
uniprot id: H8WAE2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1163748:MARHY RS02750
gene id: 1163748:MARHY_RS02750
uniprot id: H8W464
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1163748:MARHY RS15160
gene id: 1163748:MARHY_RS15160
uniprot id: H8W4P7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS00225
gene id: 1163748:MARHY_RS00225
uniprot id: H8WAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1163748:MARHY RS15215
gene id: 1163748:MARHY_RS15215
uniprot id: H8W4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1163748:MARHY RS17735
gene id: 1163748:MARHY_RS17735
uniprot id: H8W9F3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS15735
gene id: 1163748:MARHY_RS15735
uniprot id: H8W5Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1163748:MARHY RS01115
gene id: 1163748:MARHY_RS01115
uniprot id: H8WC95
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS13240
gene id: 1163748:MARHY_RS13240
uniprot id: H8WC60
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1163748:MARHY RS03105
gene id: 1163748:MARHY_RS03105
uniprot id: H8W4V0
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS17495
gene id: 1163748:MARHY_RS17495
uniprot id: H8W8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1163748:MARHY RS02780
gene id: 1163748:MARHY_RS02780
uniprot id: H8W470
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1163748:MARHY RS05650
gene id: 1163748:MARHY_RS05650
uniprot id: H8W9J3
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS06340
gene id: 1163748:MARHY_RS06340
uniprot id: H8WAI9
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1163748:MARHY RS15240
gene id: 1163748:MARHY_RS15240
uniprot id: H8W4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1163748:MARHY RS09980
gene id: 1163748:MARHY_RS09980
uniprot id: H8W6G7
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1163748:MARHY RS05295
gene id: 1163748:MARHY_RS05295
uniprot id: H8W8W0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS18265
gene id: 1163748:MARHY_RS18265
uniprot id: H8WA73
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1163748:MARHY RS07580
gene id: 1163748:MARHY_RS07580
uniprot id: H8WD48
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1163748:MARHY RS14370
gene id: 1163748:MARHY_RS14370
uniprot id: H8WE83
names: Subcellular Location Annotation
messages: Cytoplasm

1163748:MARHY RS06905
gene id: 1163748:MARHY_RS06905
uniprot id: H8WBT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS17415
gene id: 1163748:MARHY_RS17415
uniprot id: H8W8S7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1163748:MARHY RS11820
gene id: 1163748:MARHY_RS11820
uniprot id: H8W9U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1163748:MARHY RS09105
gene id: 1163748:MARHY_RS09105
uniprot id: H8W509
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS18135
gene id: 1163748:MARHY_RS18135
uniprot id: H8WA46
names: Function
names: Similarity
messages: Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia.

1163748:MARHY RS07935
gene id: 1163748:MARHY_RS07935
uniprot id: H8WDC0
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS14625
gene id: 1163748:MARHY_RS14625
uniprot id: H8WEU3
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1163748:MARHY RS14500
gene id: 1163748:MARHY_RS14500
uniprot id: H8WER8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1163748:MARHY RS08645
gene id: 1163748:MARHY_RS08645
uniprot id: H8WEP0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1163748:MARHY RS00690
gene id: 1163748:MARHY_RS00690
uniprot id: H8WBJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1163748:MARHY RS12535
gene id: 1163748:MARHY_RS12535
uniprot id: H8WBA6
names: Similarity
messages: Belongs to the PhoH family.

1163748:MARHY RS00935
gene id: 1163748:MARHY_RS00935
uniprot id: H8WBQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS03590
gene id: 1163748:MARHY_RS03590
uniprot id: H8W5K9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS11535
gene id: 1163748:MARHY_RS11535
uniprot id: H8W974
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1163748:MARHY RS00755
gene id: 1163748:MARHY_RS00755
uniprot id: H8WBL2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1163748:MARHY RS15710
gene id: 1163748:MARHY_RS15710
uniprot id: H8W5Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1163748:MARHY RS15210
gene id: 1163748:MARHY_RS15210
uniprot id: H8W4Q7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1163748:MARHY RS00960
gene id: 1163748:MARHY_RS00960
uniprot id: H8WBQ5
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1163748:MARHY RS17700
gene id: 1163748:MARHY_RS17700
uniprot id: H8W9E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1163748:MARHY RS02245
gene id: 1163748:MARHY_RS02245
uniprot id: H8WEA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1163748:MARHY RS05600
gene id: 1163748:MARHY_RS05600
uniprot id: H8W926
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1163748:MARHY RS16975
gene id: 1163748:MARHY_RS16975
uniprot id: H8W826
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS12310
gene id: 1163748:MARHY_RS12310
uniprot id: H8WAP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS16710
gene id: 1163748:MARHY_RS16710
uniprot id: H8W7G0
names: Similarity
messages: Belongs to the peptidase S11 family.

1163748:MARHY RS15140
gene id: 1163748:MARHY_RS15140
uniprot id: H8W4P3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1163748:MARHY RS04465
gene id: 1163748:MARHY_RS04465
uniprot id: H8W704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1163748:MARHY RS00010
gene id: 1163748:MARHY_RS00010
uniprot id: H8WA81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1163748:MARHY RS06755
gene id: 1163748:MARHY_RS06755
uniprot id: H8WB94
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1163748:MARHY RS03375
gene id: 1163748:MARHY_RS03375
uniprot id: H8W5G6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS00525
gene id: 1163748:MARHY_RS00525
uniprot id: H8WB06
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1163748:MARHY RS10140
gene id: 1163748:MARHY_RS10140
uniprot id: H8W6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1163748:MARHY RS06065
gene id: 1163748:MARHY_RS06065
uniprot id: H8WAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1163748:MARHY RS13540
gene id: 1163748:MARHY_RS13540
uniprot id: H8WCT7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1163748:MARHY RS12315
gene id: 1163748:MARHY_RS12315
uniprot id: H8WAP4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1163748:MARHY RS07615
gene id: 1163748:MARHY_RS07615
uniprot id: H8WD55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1163748:MARHY RS12655
gene id: 1163748:MARHY_RS12655
uniprot id: H8WBD1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS15275
gene id: 1163748:MARHY_RS15275
uniprot id: H8W581
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS16900
gene id: 1163748:MARHY_RS16900
uniprot id: H8W810
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1163748:MARHY RS11780
gene id: 1163748:MARHY_RS11780
uniprot id: H8W9T2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS04885
gene id: 1163748:MARHY_RS04885
uniprot id: H8W863
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS10060
gene id: 1163748:MARHY_RS10060
uniprot id: H8W6I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1163748:MARHY RS06825
gene id: 1163748:MARHY_RS06825
uniprot id: H8WBS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1163748:MARHY RS08850
gene id: 1163748:MARHY_RS08850
uniprot id: H8W4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1163748:MARHY RS15075
gene id: 1163748:MARHY_RS15075
uniprot id: H8W4N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1163748:MARHY RS05655
gene id: 1163748:MARHY_RS05655
uniprot id: H8W9J4
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1163748:MARHY RS09160
gene id: 1163748:MARHY_RS09160
uniprot id: H8W521
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS05175
gene id: 1163748:MARHY_RS05175
uniprot id: H8W8C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1163748:MARHY RS04575
gene id: 1163748:MARHY_RS04575
uniprot id: H8W7I6
names: Function
names: Similarity
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.

1163748:MARHY RS16865
gene id: 1163748:MARHY_RS16865
uniprot id: H8W803
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1163748:MARHY RS12730
gene id: 1163748:MARHY_RS12730
uniprot id: H8WBE6
names: Similarity
messages: Belongs to the MotB family.

1163748:MARHY RS03865
gene id: 1163748:MARHY_RS03865
uniprot id: H8W674
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1163748:MARHY RS00875
gene id: 1163748:MARHY_RS00875
uniprot id: H8WBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163748:MARHY RS09590
gene id: 1163748:MARHY_RS09590
uniprot id: H8W5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1163748:MARHY RS05680
gene id: 1163748:MARHY_RS05680
uniprot id: H8W9J9
names: Similarity
messages: Belongs to the universal stress protein A family.

1163748:MARHY RS03905
gene id: 1163748:MARHY_RS03905
uniprot id: H8W682
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1163748:MARHY RS17520
gene id: 1163748:MARHY_RS17520
uniprot id: H8W8U9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS03630
gene id: 1163748:MARHY_RS03630
uniprot id: H8W5L8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS14360
gene id: 1163748:MARHY_RS14360
uniprot id: H8WE81
names: Subcellular Location Annotation
messages: Cell inner membrane

1163748:MARHY RS10685
gene id: 1163748:MARHY_RS10685
uniprot id: H8W7T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1163748:MARHY RS03525
gene id: 1163748:MARHY_RS03525
uniprot id: H8W5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1163748:MARHY RS16100
gene id: 1163748:MARHY_RS16100
uniprot id: H8W6M5
names: Similarity
messages: Belongs to the Dps family.

1163748:MARHY RS04665
gene id: 1163748:MARHY_RS04665
uniprot id: H8W7K7
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1163748:MARHY RS16850
gene id: 1163748:MARHY_RS16850
uniprot id: H8W800
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS05960
gene id: 1163748:MARHY_RS05960
uniprot id: H8W9R0
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS02770
gene id: 1163748:MARHY_RS02770
uniprot id: H8W468
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1163748:MARHY RS12490
gene id: 1163748:MARHY_RS12490
uniprot id: H8WAS8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1163748:MARHY RS06780
gene id: 1163748:MARHY_RS06780
uniprot id: H8WB99
names: Similarity
messages: Belongs to the peptidase M16 family.

1163748:MARHY RS04485
gene id: 1163748:MARHY_RS04485
uniprot id: H8W708
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS17715
gene id: 1163748:MARHY_RS17715
uniprot id: H8W9E8
names: Subcellular Location Annotation
messages: Cytoplasm

1163748:MARHY RS04160
gene id: 1163748:MARHY_RS04160
uniprot id: H8W6U4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1163748:MARHY RS07850
gene id: 1163748:MARHY_RS07850
uniprot id: H8WDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1163748:MARHY RS17065
gene id: 1163748:MARHY_RS17065
uniprot id: H8W845
names: Subcellular Location Annotation
messages: Cell inner membrane

1163748:MARHY RS07560
gene id: 1163748:MARHY_RS07560
uniprot id: H8WCN3
names: Subcellular Location Annotation
messages: Cytoplasm

1163748:MARHY RS09930
gene id: 1163748:MARHY_RS09930
uniprot id: H8W6F6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS16020
gene id: 1163748:MARHY_RS16020
uniprot id: H8W6K9
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS15730
gene id: 1163748:MARHY_RS15730
uniprot id: H8W5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1163748:MARHY RS09470
gene id: 1163748:MARHY_RS09470
uniprot id: H8W5Q2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS09750
gene id: 1163748:MARHY_RS09750
uniprot id: H8W5V9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS11995
gene id: 1163748:MARHY_RS11995
uniprot id: H8W9X5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1163748:MARHY RS09690
gene id: 1163748:MARHY_RS09690
uniprot id: H8W5U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1163748:MARHY RS13085
gene id: 1163748:MARHY_RS13085
uniprot id: H8WC28
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1163748:MARHY RS03440
gene id: 1163748:MARHY_RS03440
uniprot id: H8W5H9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1163748:MARHY RS01240
gene id: 1163748:MARHY_RS01240
uniprot id: H8WCC1
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS09845
gene id: 1163748:MARHY_RS09845
uniprot id: H8W6D8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163748:MARHY RS03080
gene id: 1163748:MARHY_RS03080
uniprot id: H8W4U5
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1163748:MARHY RS02920
gene id: 1163748:MARHY_RS02920
uniprot id: H8W4A1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1163748:MARHY RS16750
gene id: 1163748:MARHY_RS16750
uniprot id: H8W7H0
names: Subcellular Location Annotation
messages: Cytoplasm

1163748:MARHY RS00180
gene id: 1163748:MARHY_RS00180
uniprot id: H8WAB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1163748:MARHY RS16810
gene id: 1163748:MARHY_RS16810
uniprot id: H8W7Z2
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS02600
gene id: 1163748:MARHY_RS02600
uniprot id: H8W440
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1163748:MARHY RS17555
gene id: 1163748:MARHY_RS17555
uniprot id: H8W9B3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1163748:MARHY RS01285
gene id: 1163748:MARHY_RS01285
uniprot id: H8WCD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1163748:MARHY RS00165
gene id: 1163748:MARHY_RS00165
uniprot id: H8WAB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1163748:MARHY RS07555
gene id: 1163748:MARHY_RS07555
uniprot id: H8WCN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS03370
gene id: 1163748:MARHY_RS03370
uniprot id: H8W5G5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS16230
gene id: 1163748:MARHY_RS16230
uniprot id: H8W6Q1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1163748:MARHY RS02915
gene id: 1163748:MARHY_RS02915
uniprot id: H8W4A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1163748:MARHY RS05575
gene id: 1163748:MARHY_RS05575
uniprot id: H8W921
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1163748:MARHY RS03870
gene id: 1163748:MARHY_RS03870
uniprot id: H8W675
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1163748:MARHY RS14495
gene id: 1163748:MARHY_RS14495
uniprot id: H8WER7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163748:MARHY RS04235
gene id: 1163748:MARHY_RS04235
uniprot id: H8W6V8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1163748:MARHY RS14940
gene id: 1163748:MARHY_RS14940
uniprot id: H8W4K3
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS16500
gene id: 1163748:MARHY_RS16500
uniprot id: H8W7B4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1163748:MARHY RS04275
gene id: 1163748:MARHY_RS04275
uniprot id: H8W6W6
names: Similarity
messages: Belongs to the UPF0047 family.

1163748:MARHY RS07435
gene id: 1163748:MARHY_RS07435
uniprot id: H8WCK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1163748:MARHY RS11460
gene id: 1163748:MARHY_RS11460
uniprot id: H8W959
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1163748:MARHY RS11475
gene id: 1163748:MARHY_RS11475
uniprot id: H8W962
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1163748:MARHY RS01780
gene id: 1163748:MARHY_RS01780
uniprot id: H8WD40
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1163748:MARHY RS04215
gene id: 1163748:MARHY_RS04215
uniprot id: H8W6V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1163748:MARHY RS08265
gene id: 1163748:MARHY_RS08265
uniprot id: H8WDZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1163748:MARHY RS14275
gene id: 1163748:MARHY_RS14275
uniprot id: H8WE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1163748:MARHY RS09295
gene id: 1163748:MARHY_RS09295
uniprot id: H8W554
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS18280
gene id: 1163748:MARHY_RS18280
uniprot id: H8WA76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1163748:MARHY RS09135
gene id: 1163748:MARHY_RS09135
uniprot id: H8W515
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS10080
gene id: 1163748:MARHY_RS10080
uniprot id: H8W6I7
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1163748:MARHY RS14680
gene id: 1163748:MARHY_RS14680
uniprot id: H8WEV4
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS03415
gene id: 1163748:MARHY_RS03415
uniprot id: H8W5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS06430
gene id: 1163748:MARHY_RS06430
uniprot id: H8WB29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1163748:MARHY RS08170
gene id: 1163748:MARHY_RS08170
uniprot id: H8WDX9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS12675
gene id: 1163748:MARHY_RS12675
uniprot id: H8WBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1163748:MARHY RS10340
gene id: 1163748:MARHY_RS10340
uniprot id: H8W750
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1163748:MARHY RS09235
gene id: 1163748:MARHY_RS09235
uniprot id: H8W539
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1163748:MARHY RS01890
gene id: 1163748:MARHY_RS01890
uniprot id: H8WDM2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1163748:MARHY RS01105
gene id: 1163748:MARHY_RS01105
uniprot id: H8WC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS08460
gene id: 1163748:MARHY_RS08460
uniprot id: H8WEK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1163748:MARHY RS08320
gene id: 1163748:MARHY_RS08320
uniprot id: H8WE11
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS12585
gene id: 1163748:MARHY_RS12585
uniprot id: H8WBB7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS05205
gene id: 1163748:MARHY_RS05205
uniprot id: H8W8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS00240
gene id: 1163748:MARHY_RS00240
uniprot id: H8WAU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1163748:MARHY RS16490
gene id: 1163748:MARHY_RS16490
uniprot id: H8W7B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1163748:MARHY RS10020
gene id: 1163748:MARHY_RS10020
uniprot id: H8W6H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1163748:MARHY RS04305
gene id: 1163748:MARHY_RS04305
uniprot id: H8W6X2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1163748:MARHY RS15560
gene id: 1163748:MARHY_RS15560
uniprot id: H8W5E5
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1163748:MARHY RS01765
gene id: 1163748:MARHY_RS01765
uniprot id: H8WD37
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS08780
gene id: 1163748:MARHY_RS08780
uniprot id: H8W4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1163748:MARHY RS04190
gene id: 1163748:MARHY_RS04190
uniprot id: H8W6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1163748:MARHY RS03990
gene id: 1163748:MARHY_RS03990
uniprot id: H8W699
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1163748:MARHY RS12660
gene id: 1163748:MARHY_RS12660
uniprot id: H8WBD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1163748:MARHY RS04145
gene id: 1163748:MARHY_RS04145
uniprot id: H8W6U1
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS07525
gene id: 1163748:MARHY_RS07525
uniprot id: H8WCM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1163748:MARHY RS08805
gene id: 1163748:MARHY_RS08805
uniprot id: H8W4C2
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1163748:MARHY RS14730
gene id: 1163748:MARHY_RS14730
uniprot id: H8WEW4
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

1163748:MARHY RS03790
gene id: 1163748:MARHY_RS03790
uniprot id: H8W659
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1163748:MARHY RS00040
gene id: 1163748:MARHY_RS00040
uniprot id: H8WA87
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS08565
gene id: 1163748:MARHY_RS08565
uniprot id: H8WEM3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1163748:MARHY RS16190
gene id: 1163748:MARHY_RS16190
uniprot id: H8W6P3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1163748:MARHY RS03060
gene id: 1163748:MARHY_RS03060
uniprot id: H8W4U0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS10085
gene id: 1163748:MARHY_RS10085
uniprot id: H8W6I8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1163748:MARHY RS12380
gene id: 1163748:MARHY_RS12380
uniprot id: H8WAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

1163748:MARHY RS10210
gene id: 1163748:MARHY_RS10210
uniprot id: H8W724
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1163748:MARHY RS04050
gene id: 1163748:MARHY_RS04050
uniprot id: H8W6B2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1163748:MARHY RS14995
gene id: 1163748:MARHY_RS14995
uniprot id: H8W4L4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1163748:MARHY RS11045
gene id: 1163748:MARHY_RS11045
uniprot id: H8W8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1163748:MARHY RS16195
gene id: 1163748:MARHY_RS16195
uniprot id: H8W6P4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1163748:MARHY RS16930
gene id: 1163748:MARHY_RS16930
uniprot id: H8W816
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS03520
gene id: 1163748:MARHY_RS03520
uniprot id: H8W5J5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1163748:MARHY RS00990
gene id: 1163748:MARHY_RS00990
uniprot id: H8WBR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1163748:MARHY RS16540
gene id: 1163748:MARHY_RS16540
uniprot id: H8W7C2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1163748:MARHY RS10965
gene id: 1163748:MARHY_RS10965
uniprot id: H8W8F5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1163748:MARHY RS04230
gene id: 1163748:MARHY_RS04230
uniprot id: H8W6V7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1163748:MARHY RS12590
gene id: 1163748:MARHY_RS12590
uniprot id: H8WBB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS13435
gene id: 1163748:MARHY_RS13435
uniprot id: H8WCR5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1163748:MARHY RS06090
gene id: 1163748:MARHY_RS06090
uniprot id: H8WAE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1163748:MARHY RS17395
gene id: 1163748:MARHY_RS17395
uniprot id: H8W8S3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1163748:MARHY RS01840
gene id: 1163748:MARHY_RS01840
uniprot id: H8WDL2
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

1163748:MARHY RS05835
gene id: 1163748:MARHY_RS05835
uniprot id: H8W9N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS16420
gene id: 1163748:MARHY_RS16420
uniprot id: H8W798
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1163748:MARHY RS06305
gene id: 1163748:MARHY_RS06305
uniprot id: H8WAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1163748:MARHY RS12420
gene id: 1163748:MARHY_RS12420
uniprot id: H8WAR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1163748:MARHY RS10130
gene id: 1163748:MARHY_RS10130
uniprot id: H8W6J9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1163748:MARHY RS15250
gene id: 1163748:MARHY_RS15250
uniprot id: H8W576
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1163748:MARHY RS01365
gene id: 1163748:MARHY_RS01365
uniprot id: H8WCE6
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS16240
gene id: 1163748:MARHY_RS16240
uniprot id: H8W6Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1163748:MARHY RS10290
gene id: 1163748:MARHY_RS10290
uniprot id: H8W740
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1163748:MARHY RS08830
gene id: 1163748:MARHY_RS08830
uniprot id: H8W4C7
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1163748:MARHY RS16475
gene id: 1163748:MARHY_RS16475
uniprot id: H8W7A9
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1163748:MARHY RS04495
gene id: 1163748:MARHY_RS04495
uniprot id: H8W711
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1163748:MARHY RS11685
gene id: 1163748:MARHY_RS11685
uniprot id: H8W9A3
names: Similarity
messages: Belongs to the BolA/IbaG family.

1163748:MARHY RS16740
gene id: 1163748:MARHY_RS16740
uniprot id: H8W7G8
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS17870
gene id: 1163748:MARHY_RS17870
uniprot id: H8W9I0
names: Similarity
messages: Belongs to the Lgt family.

1163748:MARHY RS12775
gene id: 1163748:MARHY_RS12775
uniprot id: H8WBF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1163748:MARHY RS01255
gene id: 1163748:MARHY_RS01255
uniprot id: H8WCC4
names: Similarity
messages: Belongs to the MotB family.

1163748:MARHY RS13285
gene id: 1163748:MARHY_RS13285
uniprot id: H8WC69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS15880
gene id: 1163748:MARHY_RS15880
uniprot id: H8W619
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1163748:MARHY RS04020
gene id: 1163748:MARHY_RS04020
uniprot id: H8W6A5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1163748:MARHY RS00365
gene id: 1163748:MARHY_RS00365
uniprot id: H8WAX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163748:MARHY RS15715
gene id: 1163748:MARHY_RS15715
uniprot id: H8W5Y3
names: Function
names: Similarity
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

1163748:MARHY RS04795
gene id: 1163748:MARHY_RS04795
uniprot id: H8W7N4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1163748:MARHY RS06925
gene id: 1163748:MARHY_RS06925
uniprot id: H8WBU1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1163748:MARHY RS10720
gene id: 1163748:MARHY_RS10720
uniprot id: H8W7U1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1163748:MARHY RS03570
gene id: 1163748:MARHY_RS03570
uniprot id: H8W5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS13155
gene id: 1163748:MARHY_RS13155
uniprot id: H8WC42
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1163748:MARHY RS06535
gene id: 1163748:MARHY_RS06535
uniprot id: H8WB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1163748:MARHY RS00740
gene id: 1163748:MARHY_RS00740
uniprot id: H8WBK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1163748:MARHY RS03775
gene id: 1163748:MARHY_RS03775
uniprot id: H8W656
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS11260
gene id: 1163748:MARHY_RS11260
uniprot id: H8W8L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1163748:MARHY RS02790
gene id: 1163748:MARHY_RS02790
uniprot id: H8W460
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1163748:MARHY RS02880
gene id: 1163748:MARHY_RS02880
uniprot id: H8W491
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1163748:MARHY RS15445
gene id: 1163748:MARHY_RS15445
uniprot id: H8W5C2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1163748:MARHY RS15165
gene id: 1163748:MARHY_RS15165
uniprot id: H8W4P8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS08965
gene id: 1163748:MARHY_RS08965
uniprot id: H8W4G2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1163748:MARHY RS03315
gene id: 1163748:MARHY_RS03315
uniprot id: H8W4Z2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1163748:MARHY RS14225
gene id: 1163748:MARHY_RS14225
uniprot id: H8WE54
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1163748:MARHY RS02805
gene id: 1163748:MARHY_RS02805
uniprot id: H8W476
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1163748:MARHY RS13395
gene id: 1163748:MARHY_RS13395
uniprot id: H8WCQ5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1163748:MARHY RS10180
gene id: 1163748:MARHY_RS10180
uniprot id: H8W718
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1163748:MARHY RS02785
gene id: 1163748:MARHY_RS02785
uniprot id: H8W471
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1163748:MARHY RS13340
gene id: 1163748:MARHY_RS13340
uniprot id: H8WCP2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1163748:MARHY RS03850
gene id: 1163748:MARHY_RS03850
uniprot id: H8W671
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1163748:MARHY RS04085
gene id: 1163748:MARHY_RS04085
uniprot id: H8W6B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1163748:MARHY RS17335
gene id: 1163748:MARHY_RS17335
uniprot id: H8W8R0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1163748:MARHY RS02830
gene id: 1163748:MARHY_RS02830
uniprot id: H8W481
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1163748:MARHY RS10730
gene id: 1163748:MARHY_RS10730
uniprot id: H8W7U3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS15395
gene id: 1163748:MARHY_RS15395
uniprot id: H8W5B1
names: Similarity
messages: Belongs to the TPP enzyme family.

1163748:MARHY RS13980
gene id: 1163748:MARHY_RS13980
uniprot id: H8WDJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1163748:MARHY RS09725
gene id: 1163748:MARHY_RS09725
uniprot id: H8W5V4
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1163748:MARHY RS18240
gene id: 1163748:MARHY_RS18240
uniprot id: H8WA68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1163748:MARHY RS16290
gene id: 1163748:MARHY_RS16290
uniprot id: H8W6R4
names: Similarity
messages: Belongs to the TrpC family.

1163748:MARHY RS14815
gene id: 1163748:MARHY_RS14815
uniprot id: H8WEY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1163748:MARHY RS10765
gene id: 1163748:MARHY_RS10765
uniprot id: H8W7V0
names: Similarity
messages: Belongs to the peptidase S16 family.

1163748:MARHY RS12810
gene id: 1163748:MARHY_RS12810
uniprot id: H8WBG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1163748:MARHY RS12225
gene id: 1163748:MARHY_RS12225
uniprot id: H8WAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1163748:MARHY RS06565
gene id: 1163748:MARHY_RS06565
uniprot id: H8WB57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1163748:MARHY RS04535
gene id: 1163748:MARHY_RS04535
uniprot id: H8W7H8
names: Similarity
messages: Belongs to the threonine synthase family.

1163748:MARHY RS16460
gene id: 1163748:MARHY_RS16460
uniprot id: H8W7A6
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1163748:MARHY RS10260
gene id: 1163748:MARHY_RS10260
uniprot id: H8W734
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1163748:MARHY RS03900
gene id: 1163748:MARHY_RS03900
uniprot id: H8W681
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS14065
gene id: 1163748:MARHY_RS14065
uniprot id: H8WE21
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1163748:MARHY RS02190
gene id: 1163748:MARHY_RS02190
uniprot id: H8WDT4
names: Similarity
messages: Belongs to the GSP E family.

1163748:MARHY RS12250
gene id: 1163748:MARHY_RS12250
uniprot id: H8WAN1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1163748:MARHY RS08670
gene id: 1163748:MARHY_RS08670
uniprot id: H8WEP5
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS16770
gene id: 1163748:MARHY_RS16770
uniprot id: H8W7Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1163748:MARHY RS15430
gene id: 1163748:MARHY_RS15430
uniprot id: H8W5B9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1163748:MARHY RS10360
gene id: 1163748:MARHY_RS10360
uniprot id: H8W754
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1163748:MARHY RS06240
gene id: 1163748:MARHY_RS06240
uniprot id: H8WAG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1163748:MARHY RS16200
gene id: 1163748:MARHY_RS16200
uniprot id: H8W6P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1163748:MARHY RS15330
gene id: 1163748:MARHY_RS15330
uniprot id: H8W592
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS09225
gene id: 1163748:MARHY_RS09225
uniprot id: H8W537
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MerP family.
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Monomer.
messages: Periplasm

1163748:MARHY RS17800
gene id: 1163748:MARHY_RS17800
uniprot id: H8W9G6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS04675
gene id: 1163748:MARHY_RS04675
uniprot id: H8W7K9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS02760
gene id: 1163748:MARHY_RS02760
uniprot id: H8W466
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1163748:MARHY RS08795
gene id: 1163748:MARHY_RS08795
uniprot id: H8W4C0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1163748:MARHY RS05190
gene id: 1163748:MARHY_RS05190
uniprot id: H8W8C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS03985
gene id: 1163748:MARHY_RS03985
uniprot id: H8W698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1163748:MARHY RS12920
gene id: 1163748:MARHY_RS12920
uniprot id: H8WBZ3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1163748:MARHY RS11200
gene id: 1163748:MARHY_RS11200
uniprot id: H8W8K1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1163748:MARHY RS12680
gene id: 1163748:MARHY_RS12680
uniprot id: H8WBD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1163748:MARHY RS08650
gene id: 1163748:MARHY_RS08650
uniprot id: H8WEP1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1163748:MARHY RS13105
gene id: 1163748:MARHY_RS13105
uniprot id: H8WC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS07595
gene id: 1163748:MARHY_RS07595
uniprot id: H8WD51
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1163748:MARHY RS13145
gene id: 1163748:MARHY_RS13145
uniprot id: H8WC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS03610
gene id: 1163748:MARHY_RS03610
uniprot id: H8W5L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1163748:MARHY RS07690
gene id: 1163748:MARHY_RS07690
uniprot id: H8WD68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1163748:MARHY RS11575
gene id: 1163748:MARHY_RS11575
uniprot id: H8W982
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1163748:MARHY RS15725
gene id: 1163748:MARHY_RS15725
uniprot id: H8W5Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1163748:MARHY RS16085
gene id: 1163748:MARHY_RS16085
uniprot id: H8W6M2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1163748:MARHY RS05695
gene id: 1163748:MARHY_RS05695
uniprot id: H8W9K2
names: Similarity
messages: Belongs to the PhzF family.

1163748:MARHY RS11180
gene id: 1163748:MARHY_RS11180
uniprot id: H8W8J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163748:MARHY RS17060
gene id: 1163748:MARHY_RS17060
uniprot id: H8W844
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1163748:MARHY RS03875
gene id: 1163748:MARHY_RS03875
uniprot id: H8W676
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1163748:MARHY RS02175
gene id: 1163748:MARHY_RS02175
uniprot id: H8WDT1
names: Similarity
messages: Belongs to the YggT family.

1163748:MARHY RS11040
gene id: 1163748:MARHY_RS11040
uniprot id: H8W8G7
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS02850
gene id: 1163748:MARHY_RS02850
uniprot id: H8W485
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1163748:MARHY RS15290
gene id: 1163748:MARHY_RS15290
uniprot id: H8W584
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1163748:MARHY RS07305
gene id: 1163748:MARHY_RS07305
uniprot id: H8WCH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

1163748:MARHY RS08235
gene id: 1163748:MARHY_RS08235
uniprot id: H8WDZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS09595
gene id: 1163748:MARHY_RS09595
uniprot id: H8W5S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

1163748:MARHY RS07070
gene id: 1163748:MARHY_RS07070
uniprot id: H8WBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1163748:MARHY RS03960
gene id: 1163748:MARHY_RS03960
uniprot id: H8W693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1163748:MARHY RS13350
gene id: 1163748:MARHY_RS13350
uniprot id: H8WCP5
names: Subcellular Location Annotation
messages: Cytoplasm

1163748:MARHY RS02765
gene id: 1163748:MARHY_RS02765
uniprot id: H8W467
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1163748:MARHY RS04525
gene id: 1163748:MARHY_RS04525
uniprot id: H8W7H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1163748:MARHY RS17795
gene id: 1163748:MARHY_RS17795
uniprot id: H8W9G5
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS03715
gene id: 1163748:MARHY_RS03715
uniprot id: H8W5N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1163748:MARHY RS08435
gene id: 1163748:MARHY_RS08435
uniprot id: H8WEJ6
names: Similarity
messages: Belongs to the peptidase S49 family.

1163748:MARHY RS12340
gene id: 1163748:MARHY_RS12340
uniprot id: H8WAP9
names: Similarity
messages: Belongs to the BolA/IbaG family.

1163748:MARHY RS08405
gene id: 1163748:MARHY_RS08405
uniprot id: H8WEJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1163748:MARHY RS03595
gene id: 1163748:MARHY_RS03595
uniprot id: H8W5L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1163748:MARHY RS16920
gene id: 1163748:MARHY_RS16920
uniprot id: H8W814
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1163748:MARHY RS00630
gene id: 1163748:MARHY_RS00630
uniprot id: H8WBI6
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1163748:MARHY RS14885
gene id: 1163748:MARHY_RS14885
uniprot id: H8W4J3
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1163748:MARHY RS05055
gene id: 1163748:MARHY_RS05055
uniprot id: H8W8A1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1163748:MARHY RS02480
gene id: 1163748:MARHY_RS02480
uniprot id: H8WEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1163748:MARHY RS11500
gene id: 1163748:MARHY_RS11500
uniprot id: H8W967
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS09575
gene id: 1163748:MARHY_RS09575
uniprot id: H8W5S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1163748:MARHY RS03755
gene id: 1163748:MARHY_RS03755
uniprot id: H8W652
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1163748:MARHY RS06740
gene id: 1163748:MARHY_RS06740
uniprot id: H8WB93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS14635
gene id: 1163748:MARHY_RS14635
uniprot id: H8WEU5
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1163748:MARHY RS14005
gene id: 1163748:MARHY_RS14005
uniprot id: H8WDJ7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS00320
gene id: 1163748:MARHY_RS00320
uniprot id: H8WAW1
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS03495
gene id: 1163748:MARHY_RS03495
uniprot id: H8W5I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1163748:MARHY RS04700
gene id: 1163748:MARHY_RS04700
uniprot id: H8W7L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1163748:MARHY RS02745
gene id: 1163748:MARHY_RS02745
uniprot id: H8W463
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1163748:MARHY RS09125
gene id: 1163748:MARHY_RS09125
uniprot id: H8W513
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS14490
gene id: 1163748:MARHY_RS14490
uniprot id: H8WER6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1163748:MARHY RS15925
gene id: 1163748:MARHY_RS15925
uniprot id: H8W629
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS11980
gene id: 1163748:MARHY_RS11980
uniprot id: H8W9X2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1163748:MARHY RS02985
gene id: 1163748:MARHY_RS02985
uniprot id: H8W4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1163748:MARHY RS12685
gene id: 1163748:MARHY_RS12685
uniprot id: H8WBD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1163748:MARHY RS16265
gene id: 1163748:MARHY_RS16265
uniprot id: H8W6Q9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1163748:MARHY RS04850
gene id: 1163748:MARHY_RS04850
uniprot id: H8W7P6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1163748:MARHY RS06785
gene id: 1163748:MARHY_RS06785
uniprot id: H8WBA0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1163748:MARHY RS00610
gene id: 1163748:MARHY_RS00610
uniprot id: H8WB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS03285
gene id: 1163748:MARHY_RS03285
uniprot id: H8W4Y6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1163748:MARHY RS01390
gene id: 1163748:MARHY_RS01390
uniprot id: H8WCF1
names: PTM
messages: Binds 1 heme group per subunit.

1163748:MARHY RS00280
gene id: 1163748:MARHY_RS00280
uniprot id: H8WAV3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1163748:MARHY RS06970
gene id: 1163748:MARHY_RS06970
uniprot id: H8WBV0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS06445
gene id: 1163748:MARHY_RS06445
uniprot id: H8WB32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS07630
gene id: 1163748:MARHY_RS07630
uniprot id: H8WD58
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1163748:MARHY RS05745
gene id: 1163748:MARHY_RS05745
uniprot id: H8W9L2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1163748:MARHY RS02185
gene id: 1163748:MARHY_RS02185
uniprot id: H8WDT3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1163748:MARHY RS04520
gene id: 1163748:MARHY_RS04520
uniprot id: H8W7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1163748:MARHY RS15135
gene id: 1163748:MARHY_RS15135
uniprot id: H8W4P2
names: Similarity
messages: Belongs to the thioredoxin family.

1163748:MARHY RS12525
gene id: 1163748:MARHY_RS12525
uniprot id: H8WBA4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS08160
gene id: 1163748:MARHY_RS08160
uniprot id: H8WDX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1163748:MARHY RS17385
gene id: 1163748:MARHY_RS17385
uniprot id: H8W8S1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1163748:MARHY RS05300
gene id: 1163748:MARHY_RS05300
uniprot id: H8W8W1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS01975
gene id: 1163748:MARHY_RS01975
uniprot id: H8WDN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1163748:MARHY RS02250
gene id: 1163748:MARHY_RS02250
uniprot id: H8WEA8
names: Similarity
messages: Belongs to the YicC/YloC family.

1163748:MARHY RS08615
gene id: 1163748:MARHY_RS08615
uniprot id: H8WEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1163748:MARHY RS12450
gene id: 1163748:MARHY_RS12450
uniprot id: H8WAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1163748:MARHY RS08720
gene id: 1163748:MARHY_RS08720
uniprot id: H8W4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS02725
gene id: 1163748:MARHY_RS02725
uniprot id: H8W460
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1163748:MARHY RS08685
gene id: 1163748:MARHY_RS08685
uniprot id: H8WEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS00300
gene id: 1163748:MARHY_RS00300
uniprot id: H8WAV7
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1163748:MARHY RS12170
gene id: 1163748:MARHY_RS12170
uniprot id: H8WAL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS03470
gene id: 1163748:MARHY_RS03470
uniprot id: H8W5I4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS17975
gene id: 1163748:MARHY_RS17975
uniprot id: H8WA11
names: Similarity
messages: Belongs to the Gfa family.

1163748:MARHY RS09285
gene id: 1163748:MARHY_RS09285
uniprot id: H8W550
names: Similarity
messages: Belongs to the PhzF family.

1163748:MARHY RS06580
gene id: 1163748:MARHY_RS06580
uniprot id: H8WB60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1163748:MARHY RS12375
gene id: 1163748:MARHY_RS12375
uniprot id: H8WAQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1163748:MARHY RS13100
gene id: 1163748:MARHY_RS13100
uniprot id: H8WC31
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS12740
gene id: 1163748:MARHY_RS12740
uniprot id: H8WBE8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1163748:MARHY RS05125
gene id: 1163748:MARHY_RS05125
uniprot id: H8W8B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1163748:MARHY RS05615
gene id: 1163748:MARHY_RS05615
uniprot id: H8W929
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1163748:MARHY RS15545
gene id: 1163748:MARHY_RS15545
uniprot id: H8W5E2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1163748:MARHY RS08490
gene id: 1163748:MARHY_RS08490
uniprot id: H8WEK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1163748:MARHY RS00020
gene id: 1163748:MARHY_RS00020
uniprot id: H8WA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1163748:MARHY RS16760
gene id: 1163748:MARHY_RS16760
uniprot id: H8W7Y2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS03485
gene id: 1163748:MARHY_RS03485
uniprot id: H8W5I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1163748:MARHY RS15860
gene id: 1163748:MARHY_RS15860
uniprot id: H8W615
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1163748:MARHY RS04530
gene id: 1163748:MARHY_RS04530
uniprot id: H8W7H7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1163748:MARHY RS07055
gene id: 1163748:MARHY_RS07055
uniprot id: H8WBW5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1163748:MARHY RS02465
gene id: 1163748:MARHY_RS02465
uniprot id: H8WEF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1163748:MARHY RS10500
gene id: 1163748:MARHY_RS10500
uniprot id: H8W783
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS15575
gene id: 1163748:MARHY_RS15575
uniprot id: H8W5E8
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1163748:MARHY RS10545
gene id: 1163748:MARHY_RS10545
uniprot id: H8W7Q5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

1163748:MARHY RS18310
gene id: 1163748:MARHY_RS18310
uniprot id: H8WAT5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS11275
gene id: 1163748:MARHY_RS11275
uniprot id: H8W8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1163748:MARHY RS09580
gene id: 1163748:MARHY_RS09580
uniprot id: H8W5S5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1163748:MARHY RS10445
gene id: 1163748:MARHY_RS10445
uniprot id: H8W772
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1163748:MARHY RS04785
gene id: 1163748:MARHY_RS04785
uniprot id: H8W7N2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1163748:MARHY RS09850
gene id: 1163748:MARHY_RS09850
uniprot id: H8W6D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1163748:MARHY RS04515
gene id: 1163748:MARHY_RS04515
uniprot id: H8W7H4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1163748:MARHY RS08755
gene id: 1163748:MARHY_RS08755
uniprot id: H8W4B1
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1163748:MARHY RS03600
gene id: 1163748:MARHY_RS03600
uniprot id: H8W5L1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1163748:MARHY RS17390
gene id: 1163748:MARHY_RS17390
uniprot id: H8W8S2
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS15370
gene id: 1163748:MARHY_RS15370
uniprot id: H8W5A6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1163748:MARHY RS01510
gene id: 1163748:MARHY_RS01510
uniprot id: H8WCY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163748:MARHY RS13665
gene id: 1163748:MARHY_RS13665
uniprot id: H8WDC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1163748:MARHY RS08360
gene id: 1163748:MARHY_RS08360
uniprot id: H8WEI0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1163748:MARHY RS01060
gene id: 1163748:MARHY_RS01060
uniprot id: H8WC84
names: Caution
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS07640
gene id: 1163748:MARHY_RS07640
uniprot id: H8WD60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1163748:MARHY RS06530
gene id: 1163748:MARHY_RS06530
uniprot id: H8WB50
names: Similarity
messages: Belongs to the YkuD family.

1163748:MARHY RS14455
gene id: 1163748:MARHY_RS14455
uniprot id: H8WEQ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS01170
gene id: 1163748:MARHY_RS01170
uniprot id: H8WCA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1163748:MARHY RS01420
gene id: 1163748:MARHY_RS01420
uniprot id: H8WCW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1163748:MARHY RS06440
gene id: 1163748:MARHY_RS06440
uniprot id: H8WB31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1163748:MARHY RS11170
gene id: 1163748:MARHY_RS11170
uniprot id: H8W8J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163748:MARHY RS15325
gene id: 1163748:MARHY_RS15325
uniprot id: H8W591
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1163748:MARHY RS07440
gene id: 1163748:MARHY_RS07440
uniprot id: H8WCK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1163748:MARHY RS01785
gene id: 1163748:MARHY_RS01785
uniprot id: H8WD41
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1163748:MARHY RS16235
gene id: 1163748:MARHY_RS16235
uniprot id: H8W6Q2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1163748:MARHY RS08710
gene id: 1163748:MARHY_RS08710
uniprot id: H8WEQ4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1163748:MARHY RS06960
gene id: 1163748:MARHY_RS06960
uniprot id: H8WBU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1163748:MARHY RS03820
gene id: 1163748:MARHY_RS03820
uniprot id: H8W665
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1163748:MARHY RS03720
gene id: 1163748:MARHY_RS03720
uniprot id: H8W645
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1163748:MARHY RS03685
gene id: 1163748:MARHY_RS03685
uniprot id: H8W5M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS04825
gene id: 1163748:MARHY_RS04825
uniprot id: H8W7P0
names: Similarity
messages: Belongs to the fatty acyl-CoA reductase family.

1163748:MARHY RS01025
gene id: 1163748:MARHY_RS01025
uniprot id: H8WC76
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1163748:MARHY RS11135
gene id: 1163748:MARHY_RS11135
uniprot id: H8W8I7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1163748:MARHY RS14850
gene id: 1163748:MARHY_RS14850
uniprot id: H8W4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1163748:MARHY RS18245
gene id: 1163748:MARHY_RS18245
uniprot id: H8WA69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1163748:MARHY RS09655
gene id: 1163748:MARHY_RS09655
uniprot id: H8W5U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1163748:MARHY RS04780
gene id: 1163748:MARHY_RS04780
uniprot id: H8W7N1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1163748:MARHY RS15055
gene id: 1163748:MARHY_RS15055
uniprot id: H8W4M6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1163748:MARHY RS07395
gene id: 1163748:MARHY_RS07395
uniprot id: H8WCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1163748:MARHY RS10335
gene id: 1163748:MARHY_RS10335
uniprot id: H8W749
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1163748:MARHY RS05860
gene id: 1163748:MARHY_RS05860
uniprot id: H8W9N6
names: Similarity
messages: Belongs to the peptidase M1 family.

1163748:MARHY RS07760
gene id: 1163748:MARHY_RS07760
uniprot id: H8WD82
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1163748:MARHY RS16005
gene id: 1163748:MARHY_RS16005
uniprot id: H8W6K5
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS14190
gene id: 1163748:MARHY_RS14190
uniprot id: H8WE47
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS05890
gene id: 1163748:MARHY_RS05890
uniprot id: H8W9P3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS11155
gene id: 1163748:MARHY_RS11155
uniprot id: H8W8J1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS15460
gene id: 1163748:MARHY_RS15460
uniprot id: H8W5C5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS06450
gene id: 1163748:MARHY_RS06450
uniprot id: H8WB33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1163748:MARHY RS15755
gene id: 1163748:MARHY_RS15755
uniprot id: H8W5Z1
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1163748:MARHY RS16660
gene id: 1163748:MARHY_RS16660
uniprot id: H8W7E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1163748:MARHY RS03795
gene id: 1163748:MARHY_RS03795
uniprot id: H8W660
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1163748:MARHY RS00140
gene id: 1163748:MARHY_RS00140
uniprot id: H8WAA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1163748:MARHY RS14880
gene id: 1163748:MARHY_RS14880
uniprot id: H8W4J2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1163748:MARHY RS07450
gene id: 1163748:MARHY_RS07450
uniprot id: H8WCL0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1163748:MARHY RS05200
gene id: 1163748:MARHY_RS05200
uniprot id: H8W8D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS04265
gene id: 1163748:MARHY_RS04265
uniprot id: H8W6W4
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1163748:MARHY RS10710
gene id: 1163748:MARHY_RS10710
uniprot id: H8W7T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1163748:MARHY RS03945
gene id: 1163748:MARHY_RS03945
uniprot id: H8W690
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS06290
gene id: 1163748:MARHY_RS06290
uniprot id: H8WAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1163748:MARHY RS18335
gene id: 1163748:MARHY_RS18335
uniprot id: H8WAU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1163748:MARHY RS05975
gene id: 1163748:MARHY_RS05975
uniprot id: H8W9R2
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS16895
gene id: 1163748:MARHY_RS16895
uniprot id: H8W809
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS15425
gene id: 1163748:MARHY_RS15425
uniprot id: H8W5B8
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1163748:MARHY RS04540
gene id: 1163748:MARHY_RS04540
uniprot id: H8W7H9
names: Similarity
messages: Belongs to the RecJ family.

1163748:MARHY RS03895
gene id: 1163748:MARHY_RS03895
uniprot id: H8W680
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1163748:MARHY RS17985
gene id: 1163748:MARHY_RS17985
uniprot id: H8WA13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS00465
gene id: 1163748:MARHY_RS00465
uniprot id: H8WAZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS08640
gene id: 1163748:MARHY_RS08640
uniprot id: H8WEN8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1163748:MARHY RS02285
gene id: 1163748:MARHY_RS02285
uniprot id: H8WEB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS01250
gene id: 1163748:MARHY_RS01250
uniprot id: H8WCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1163748:MARHY RS04105
gene id: 1163748:MARHY_RS04105
uniprot id: H8W6C3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1163748:MARHY RS06560
gene id: 1163748:MARHY_RS06560
uniprot id: H8WB56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1163748:MARHY RS02550
gene id: 1163748:MARHY_RS02550
uniprot id: H8WEH4
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1163748:MARHY RS03785
gene id: 1163748:MARHY_RS03785
uniprot id: H8W658
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS06455
gene id: 1163748:MARHY_RS06455
uniprot id: H8WB34
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1163748:MARHY RS11450
gene id: 1163748:MARHY_RS11450
uniprot id: H8W957
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1163748:MARHY RS03675
gene id: 1163748:MARHY_RS03675
uniprot id: H8W5M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1163748:MARHY RS18225
gene id: 1163748:MARHY_RS18225
uniprot id: H8WA65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1163748:MARHY RS08020
gene id: 1163748:MARHY_RS08020
uniprot id: H8WDU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1163748:MARHY RS09570
gene id: 1163748:MARHY_RS09570
uniprot id: H8W5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1163748:MARHY RS03860
gene id: 1163748:MARHY_RS03860
uniprot id: H8W673
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1163748:MARHY RS06085
gene id: 1163748:MARHY_RS06085
uniprot id: H8WAE0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1163748:MARHY RS13400
gene id: 1163748:MARHY_RS13400
uniprot id: H8WCQ7
names: Similarity
messages: Belongs to the elongation factor P family.

1163748:MARHY RS10520
gene id: 1163748:MARHY_RS10520
uniprot id: H8W788
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1163748:MARHY RS13845
gene id: 1163748:MARHY_RS13845
uniprot id: H8WDG1
names: Similarity
messages: Belongs to the LOG family.

1163748:MARHY RS08045
gene id: 1163748:MARHY_RS08045
uniprot id: H8WDV4
names: Similarity
messages: Belongs to the UPF0260 family.

1163748:MARHY RS07175
gene id: 1163748:MARHY_RS07175
uniprot id: H8WBZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163748:MARHY RS03500
gene id: 1163748:MARHY_RS03500
uniprot id: H8W5J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS11265
gene id: 1163748:MARHY_RS11265
uniprot id: H8W8L4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS12865
gene id: 1163748:MARHY_RS12865
uniprot id: H8WBH3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1163748:MARHY RS11730
gene id: 1163748:MARHY_RS11730
uniprot id: H8W9S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1163748:MARHY RS09915
gene id: 1163748:MARHY_RS09915
uniprot id: H8W6F3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS02980
gene id: 1163748:MARHY_RS02980
uniprot id: H8W4S4
names: Similarity
messages: Belongs to the GSP E family.

1163748:MARHY RS10355
gene id: 1163748:MARHY_RS10355
uniprot id: H8W753
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1163748:MARHY RS03780
gene id: 1163748:MARHY_RS03780
uniprot id: H8W657
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1163748:MARHY RS06145
gene id: 1163748:MARHY_RS06145
uniprot id: H8WAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1163748:MARHY RS04645
gene id: 1163748:MARHY_RS04645
uniprot id: H8W7K3
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS07390
gene id: 1163748:MARHY_RS07390
uniprot id: H8WCJ7
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1163748:MARHY RS11030
gene id: 1163748:MARHY_RS11030
uniprot id: H8W8G5
names: Similarity
messages: Belongs to the aspartokinase family.

1163748:MARHY RS07220
gene id: 1163748:MARHY_RS07220
uniprot id: H8WCG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1163748:MARHY RS05750
gene id: 1163748:MARHY_RS05750
uniprot id: H8W9L3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1163748:MARHY RS04125
gene id: 1163748:MARHY_RS04125
uniprot id: H8W6T6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1163748:MARHY RS09685
gene id: 1163748:MARHY_RS09685
uniprot id: H8W5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1163748:MARHY RS05140
gene id: 1163748:MARHY_RS05140
uniprot id: H8W8B8
names: Similarity
messages: Belongs to the VgrG protein family.

1163748:MARHY RS14630
gene id: 1163748:MARHY_RS14630
uniprot id: H8WEU4
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1163748:MARHY RS04630
gene id: 1163748:MARHY_RS04630
uniprot id: H8W7J8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1163748:MARHY RS16565
gene id: 1163748:MARHY_RS16565
uniprot id: H8W7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1163748:MARHY RS01455
gene id: 1163748:MARHY_RS01455
uniprot id: H8WCX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1163748:MARHY RS16025
gene id: 1163748:MARHY_RS16025
uniprot id: H8W6L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1163748:MARHY RS03890
gene id: 1163748:MARHY_RS03890
uniprot id: H8W679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS04430
gene id: 1163748:MARHY_RS04430
uniprot id: H8W6Z7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1163748:MARHY RS16575
gene id: 1163748:MARHY_RS16575
uniprot id: H8W7D1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1163748:MARHY RS18150
gene id: 1163748:MARHY_RS18150
uniprot id: H8WA49
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS08100
gene id: 1163748:MARHY_RS08100
uniprot id: H8WDW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163748:MARHY RS05185
gene id: 1163748:MARHY_RS05185
uniprot id: H8W8C7
names: Similarity
messages: Belongs to the proline racemase family.

1163748:MARHY RS05675
gene id: 1163748:MARHY_RS05675
uniprot id: H8W9J8
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS04710
gene id: 1163748:MARHY_RS04710
uniprot id: H8W7L7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1163748:MARHY RS14010
gene id: 1163748:MARHY_RS14010
uniprot id: H8WDJ8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS15320
gene id: 1163748:MARHY_RS15320
uniprot id: H8W590
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1163748:MARHY RS07660
gene id: 1163748:MARHY_RS07660
uniprot id: H8WD64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1163748:MARHY RS16990
gene id: 1163748:MARHY_RS16990
uniprot id: H8W829
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1163748:MARHY RS16340
gene id: 1163748:MARHY_RS16340
uniprot id: H8W6S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1163748:MARHY RS14295
gene id: 1163748:MARHY_RS14295
uniprot id: H8WE68
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS16520
gene id: 1163748:MARHY_RS16520
uniprot id: H8W7B8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1163748:MARHY RS08860
gene id: 1163748:MARHY_RS08860
uniprot id: H8W4D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1163748:MARHY RS12860
gene id: 1163748:MARHY_RS12860
uniprot id: H8WBH2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS16225
gene id: 1163748:MARHY_RS16225
uniprot id: H8W6Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1163748:MARHY RS14985
gene id: 1163748:MARHY_RS14985
uniprot id: H8W4L2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163748:MARHY RS12360
gene id: 1163748:MARHY_RS12360
uniprot id: H8WAQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1163748:MARHY RS18210
gene id: 1163748:MARHY_RS18210
uniprot id: H8WA62
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS10205
gene id: 1163748:MARHY_RS10205
uniprot id: H8W723
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1163748:MARHY RS05920
gene id: 1163748:MARHY_RS05920
uniprot id: H8W9Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1163748:MARHY RS04895
gene id: 1163748:MARHY_RS04895
uniprot id: H8W865
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1163748:MARHY RS13310
gene id: 1163748:MARHY_RS13310
uniprot id: H8WCN6
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1163748:MARHY RS07420
gene id: 1163748:MARHY_RS07420
uniprot id: H8WCK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1163748:MARHY RS02930
gene id: 1163748:MARHY_RS02930
uniprot id: H8W4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1163748:MARHY RS08775
gene id: 1163748:MARHY_RS08775
uniprot id: H8W4B5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1163748:MARHY RS04615
gene id: 1163748:MARHY_RS04615
uniprot id: H8W7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS00680
gene id: 1163748:MARHY_RS00680
uniprot id: H8WBJ6
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1163748:MARHY RS14755
gene id: 1163748:MARHY_RS14755
uniprot id: H8WEW9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1163748:MARHY RS05525
gene id: 1163748:MARHY_RS05525
uniprot id: H8W911
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS12665
gene id: 1163748:MARHY_RS12665
uniprot id: H8WBD3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1163748:MARHY RS05495
gene id: 1163748:MARHY_RS05495
uniprot id: H8W905
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1163748:MARHY RS01195
gene id: 1163748:MARHY_RS01195
uniprot id: H8WCB2
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1163748:MARHY RS08400
gene id: 1163748:MARHY_RS08400
uniprot id: H8WEI8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1163748:MARHY RS12640
gene id: 1163748:MARHY_RS12640
uniprot id: H8WBC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1163748:MARHY RS12030
gene id: 1163748:MARHY_RS12030
uniprot id: H8W9Y3
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1163748:MARHY RS02820
gene id: 1163748:MARHY_RS02820
uniprot id: H8W479
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1163748:MARHY RS16815
gene id: 1163748:MARHY_RS16815
uniprot id: H8W7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1163748:MARHY RS04225
gene id: 1163748:MARHY_RS04225
uniprot id: H8W6V6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1163748:MARHY RS04975
gene id: 1163748:MARHY_RS04975
uniprot id: H8W882
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS16755
gene id: 1163748:MARHY_RS16755
uniprot id: H8W7H1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1163748:MARHY RS03920
gene id: 1163748:MARHY_RS03920
uniprot id: H8W685
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
messages: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS07965
gene id: 1163748:MARHY_RS07965
uniprot id: H8WDT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1163748:MARHY RS05210
gene id: 1163748:MARHY_RS05210
uniprot id: H8W8D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1163748:MARHY RS02445
gene id: 1163748:MARHY_RS02445
uniprot id: A0A8B0N6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1163748:MARHY RS00940
gene id: 1163748:MARHY_RS00940
uniprot id: H8WBQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1163748:MARHY RS14810
gene id: 1163748:MARHY_RS14810
uniprot id: H8WEY0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1163748:MARHY RS05570
gene id: 1163748:MARHY_RS05570
uniprot id: H8W920
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS18230
gene id: 1163748:MARHY_RS18230
uniprot id: H8WA66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1163748:MARHY RS03330
gene id: 1163748:MARHY_RS03330
uniprot id: H8W5F7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1163748:MARHY RS15640
gene id: 1163748:MARHY_RS15640
uniprot id: H8W5W8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1163748:MARHY RS16000
gene id: 1163748:MARHY_RS16000
uniprot id: H8W6K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1163748:MARHY RS18455
gene id: 1163748:MARHY_RS18455
uniprot id: H8W497
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1163748:MARHY RS16700
gene id: 1163748:MARHY_RS16700
uniprot id: H8W7F8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1163748:MARHY RS01750
gene id: 1163748:MARHY_RS01750
uniprot id: H8WD34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS04510
gene id: 1163748:MARHY_RS04510
uniprot id: H8W7H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1163748:MARHY RS00100
gene id: 1163748:MARHY_RS00100
uniprot id: H8WA99
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS16640
gene id: 1163748:MARHY_RS16640
uniprot id: H8W7E5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1163748:MARHY RS09560
gene id: 1163748:MARHY_RS09560
uniprot id: H8W5S1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1163748:MARHY RS05490
gene id: 1163748:MARHY_RS05490
uniprot id: H8W904
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1163748:MARHY RS06295
gene id: 1163748:MARHY_RS06295
uniprot id: H8WAI0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1163748:MARHY RS08305
gene id: 1163748:MARHY_RS08305
uniprot id: H8WE08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1163748:MARHY RS01820
gene id: 1163748:MARHY_RS01820
uniprot id: H8WDK7
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1163748:MARHY RS10105
gene id: 1163748:MARHY_RS10105
uniprot id: H8W6J3
names: Similarity
messages: Belongs to the citrate synthase family.

1163748:MARHY RS03410
gene id: 1163748:MARHY_RS03410
uniprot id: H8W5H3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1163748:MARHY RS17220
gene id: 1163748:MARHY_RS17220
uniprot id: H8W8N5
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS11925
gene id: 1163748:MARHY_RS11925
uniprot id: H8W9W1
names: Similarity
messages: Belongs to the UPF0234 family.

1163748:MARHY RS06150
gene id: 1163748:MARHY_RS06150
uniprot id: H8WAE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS13135
gene id: 1163748:MARHY_RS13135
uniprot id: H8WC38
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS10745
gene id: 1163748:MARHY_RS10745
uniprot id: H8W7U6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1163748:MARHY RS10320
gene id: 1163748:MARHY_RS10320
uniprot id: H8W745
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1163748:MARHY RS04715
gene id: 1163748:MARHY_RS04715
uniprot id: H8W7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1163748:MARHY RS08255
gene id: 1163748:MARHY_RS08255
uniprot id: H8WDZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS10670
gene id: 1163748:MARHY_RS10670
uniprot id: H8W7T0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1163748:MARHY RS14830
gene id: 1163748:MARHY_RS14830
uniprot id: H8WEY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1163748:MARHY RS00520
gene id: 1163748:MARHY_RS00520
uniprot id: H8WB05
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS04365
gene id: 1163748:MARHY_RS04365
uniprot id: H8W6Y4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1163748:MARHY RS02810
gene id: 1163748:MARHY_RS02810
uniprot id: H8W477
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1163748:MARHY RS05605
gene id: 1163748:MARHY_RS05605
uniprot id: H8W927
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS14960
gene id: 1163748:MARHY_RS14960
uniprot id: H8W4K7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS15515
gene id: 1163748:MARHY_RS15515
uniprot id: H8W5D6
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1163748:MARHY RS13935
gene id: 1163748:MARHY_RS13935
uniprot id: H8WDI0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1163748:MARHY RS06810
gene id: 1163748:MARHY_RS06810
uniprot id: H8WBR7
names: Similarity
messages: Belongs to the YciI family.

1163748:MARHY RS04865
gene id: 1163748:MARHY_RS04865
uniprot id: H8W7P9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1163748:MARHY RS09755
gene id: 1163748:MARHY_RS09755
uniprot id: H8W5W0
names: Subcellular Location Annotation
messages: Cytoplasm

1163748:MARHY RS14905
gene id: 1163748:MARHY_RS14905
uniprot id: H8W4J6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163748:MARHY RS04325
gene id: 1163748:MARHY_RS04325
uniprot id: H8W6X6
names: Similarity
messages: Belongs to the TPP enzyme family.

1163748:MARHY RS15820
gene id: 1163748:MARHY_RS15820
uniprot id: H8W605
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1163748:MARHY RS09625
gene id: 1163748:MARHY_RS09625
uniprot id: H8W5T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1163748:MARHY RS01210
gene id: 1163748:MARHY_RS01210
uniprot id: H8WCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS15280
gene id: 1163748:MARHY_RS15280
uniprot id: H8W582
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1163748:MARHY RS11750
gene id: 1163748:MARHY_RS11750
uniprot id: H8W9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1163748:MARHY RS13140
gene id: 1163748:MARHY_RS13140
uniprot id: H8WC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS07015
gene id: 1163748:MARHY_RS07015
uniprot id: H8WBV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1163748:MARHY RS17210
gene id: 1163748:MARHY_RS17210
uniprot id: H8W8N3
names: Similarity
messages: Belongs to the PspA/IM30 family.

1163748:MARHY RS11510
gene id: 1163748:MARHY_RS11510
uniprot id: H8W969
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

1163748:MARHY RS03230
gene id: 1163748:MARHY_RS03230
uniprot id: H8W4X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1163748:MARHY RS06355
gene id: 1163748:MARHY_RS06355
uniprot id: H8WAJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1163748:MARHY RS12055
gene id: 1163748:MARHY_RS12055
uniprot id: H8W9Y9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1163748:MARHY RS06320
gene id: 1163748:MARHY_RS06320
uniprot id: H8WAI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1163748:MARHY RS11505
gene id: 1163748:MARHY_RS11505
uniprot id: H8W968
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1163748:MARHY RS11365
gene id: 1163748:MARHY_RS11365
uniprot id: H8W946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1163748:MARHY RS05905
gene id: 1163748:MARHY_RS05905
uniprot id: H8W9P8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1163748:MARHY RS00185
gene id: 1163748:MARHY_RS00185
uniprot id: H8WAB5
names: Similarity
messages: Belongs to the MotB family.

1163748:MARHY RS15760
gene id: 1163748:MARHY_RS15760
uniprot id: H8W5Z2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1163748:MARHY RS15655
gene id: 1163748:MARHY_RS15655
uniprot id: H8W5X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS02640
gene id: 1163748:MARHY_RS02640
uniprot id: H8W448
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS13070
gene id: 1163748:MARHY_RS13070
uniprot id: H8WC24
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1163748:MARHY RS08270
gene id: 1163748:MARHY_RS08270
uniprot id: H8WE00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS15155
gene id: 1163748:MARHY_RS15155
uniprot id: H8W4P6
names: Similarity
messages: Belongs to the leucine-binding protein family.

1163748:MARHY RS02900
gene id: 1163748:MARHY_RS02900
uniprot id: H8W496
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1163748:MARHY RS03425
gene id: 1163748:MARHY_RS03425
uniprot id: H8W5H6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1163748:MARHY RS07505
gene id: 1163748:MARHY_RS07505
uniprot id: H8WCM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163748:MARHY RS16855
gene id: 1163748:MARHY_RS16855
uniprot id: H8W801
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1163748:MARHY RS04005
gene id: 1163748:MARHY_RS04005
uniprot id: H8W6A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1163748:MARHY RS13670
gene id: 1163748:MARHY_RS13670
uniprot id: H8WDC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1163748:MARHY RS16800
gene id: 1163748:MARHY_RS16800
uniprot id: H8W7Z0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1163748:MARHY RS09350
gene id: 1163748:MARHY_RS09350
uniprot id: H8W566
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1163748:MARHY RS00605
gene id: 1163748:MARHY_RS00605
uniprot id: H8WB21
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1163748:MARHY RS03980
gene id: 1163748:MARHY_RS03980
uniprot id: H8W697
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1163748:MARHY RS10040
gene id: 1163748:MARHY_RS10040
uniprot id: H8W6H9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1163748:MARHY RS03935
gene id: 1163748:MARHY_RS03935
uniprot id: H8W688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1163748:MARHY RS02800
gene id: 1163748:MARHY_RS02800
uniprot id: H8W475
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1163748:MARHY RS13975
gene id: 1163748:MARHY_RS13975
uniprot id: H8WDJ0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1163748:MARHY RS03805
gene id: 1163748:MARHY_RS03805
uniprot id: H8W662
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1163748:MARHY RS06920
gene id: 1163748:MARHY_RS06920
uniprot id: H8WBU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS03830
gene id: 1163748:MARHY_RS03830
uniprot id: H8W667
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1163748:MARHY RS16205
gene id: 1163748:MARHY_RS16205
uniprot id: H8W6P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1163748:MARHY RS11555
gene id: 1163748:MARHY_RS11555
uniprot id: H8W978
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1163748:MARHY RS06590
gene id: 1163748:MARHY_RS06590
uniprot id: H8WB62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1163748:MARHY RS09370
gene id: 1163748:MARHY_RS09370
uniprot id: H8W571
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1163748:MARHY RS10195
gene id: 1163748:MARHY_RS10195
uniprot id: H8W721
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1163748:MARHY RS12650
gene id: 1163748:MARHY_RS12650
uniprot id: H8WBD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1163748:MARHY RS00095
gene id: 1163748:MARHY_RS00095
uniprot id: H8WA98
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS03765
gene id: 1163748:MARHY_RS03765
uniprot id: H8W654
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1163748:MARHY RS03270
gene id: 1163748:MARHY_RS03270
uniprot id: H8W4Y3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1163748:MARHY RS12195
gene id: 1163748:MARHY_RS12195
uniprot id: H8WAM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1163748:MARHY RS11160
gene id: 1163748:MARHY_RS11160
uniprot id: H8W8J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1163748:MARHY RS06965
gene id: 1163748:MARHY_RS06965
uniprot id: H8WBU9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1163748:MARHY RS09250
gene id: 1163748:MARHY_RS09250
uniprot id: H8W543
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS09280
gene id: 1163748:MARHY_RS09280
uniprot id: H8W549
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS16965
gene id: 1163748:MARHY_RS16965
uniprot id: H8W824
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1163748:MARHY RS06360
gene id: 1163748:MARHY_RS06360
uniprot id: H8WAJ3
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1163748:MARHY RS07940
gene id: 1163748:MARHY_RS07940
uniprot id: H8WDC1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1163748:MARHY RS11035
gene id: 1163748:MARHY_RS11035
uniprot id: H8W8G6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1163748:MARHY RS03260
gene id: 1163748:MARHY_RS03260
uniprot id: H8W4Y1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1163748:MARHY RS14840
gene id: 1163748:MARHY_RS14840
uniprot id: H8WEY6
names: Similarity
messages: Belongs to the peptidase S41A family.

1163748:MARHY RS09400
gene id: 1163748:MARHY_RS09400
uniprot id: H8W5N5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS12370
gene id: 1163748:MARHY_RS12370
uniprot id: H8WAQ5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1163748:MARHY RS09865
gene id: 1163748:MARHY_RS09865
uniprot id: H8W6E2
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1163748:MARHY RS02235
gene id: 1163748:MARHY_RS02235
uniprot id: H8WEA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1163748:MARHY RS14570
gene id: 1163748:MARHY_RS14570
uniprot id: H8WET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1163748:MARHY RS01070
gene id: 1163748:MARHY_RS01070
uniprot id: H8WC86
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1163748:MARHY RS13380
gene id: 1163748:MARHY_RS13380
uniprot id: H8WCQ2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1163748:MARHY RS15230
gene id: 1163748:MARHY_RS15230
uniprot id: H8W4R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1163748:MARHY RS02605
gene id: 1163748:MARHY_RS02605
uniprot id: H8W441
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS15720
gene id: 1163748:MARHY_RS15720
uniprot id: H8W5Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS14585
gene id: 1163748:MARHY_RS14585
uniprot id: H8WET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS00050
gene id: 1163748:MARHY_RS00050
uniprot id: H8WA89
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1163748:MARHY RS10415
gene id: 1163748:MARHY_RS10415
uniprot id: H8W765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS06285
gene id: 1163748:MARHY_RS06285
uniprot id: H8WAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1163748:MARHY RS01590
gene id: 1163748:MARHY_RS01590
uniprot id: H8WD03
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1163748:MARHY RS11525
gene id: 1163748:MARHY_RS11525
uniprot id: H8W972
names: Similarity
messages: Belongs to the UPF0246 family.

1163748:MARHY RS11825
gene id: 1163748:MARHY_RS11825
uniprot id: H8W9U1
names: Similarity
messages: Belongs to the SlyX family.

1163748:MARHY RS05885
gene id: 1163748:MARHY_RS05885
uniprot id: H8W9P2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1163748:MARHY RS03530
gene id: 1163748:MARHY_RS03530
uniprot id: H8W5J7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1163748:MARHY RS10295
gene id: 1163748:MARHY_RS10295
uniprot id: H8W741
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1163748:MARHY RS16510
gene id: 1163748:MARHY_RS16510
uniprot id: H8W7B6
names: Similarity
messages: Belongs to the UPF0758 family.

1163748:MARHY RS06045
gene id: 1163748:MARHY_RS06045
uniprot id: H8WAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1163748:MARHY RS10740
gene id: 1163748:MARHY_RS10740
uniprot id: H8W7U5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1163748:MARHY RS16645
gene id: 1163748:MARHY_RS16645
uniprot id: H8W7E6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1163748:MARHY RS05665
gene id: 1163748:MARHY_RS05665
uniprot id: H8W9J6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1163748:MARHY RS00635
gene id: 1163748:MARHY_RS00635
uniprot id: H8WBI7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1163748:MARHY RS06550
gene id: 1163748:MARHY_RS06550
uniprot id: H8WB54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1163748:MARHY RS09905
gene id: 1163748:MARHY_RS09905
uniprot id: H8W6F1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1163748:MARHY RS06315
gene id: 1163748:MARHY_RS06315
uniprot id: H8WAI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1163748:MARHY RS04155
gene id: 1163748:MARHY_RS04155
uniprot id: H8W6U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1163748:MARHY RS03405
gene id: 1163748:MARHY_RS03405
uniprot id: H8W5H2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1163748:MARHY RS14690
gene id: 1163748:MARHY_RS14690
uniprot id: H8WEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1163748:MARHY RS01330
gene id: 1163748:MARHY_RS01330
uniprot id: H8WCD9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1163748:MARHY RS12470
gene id: 1163748:MARHY_RS12470
uniprot id: H8WAS4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1163748:MARHY RS06830
gene id: 1163748:MARHY_RS06830
uniprot id: H8WBS2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1163748:MARHY RS04470
gene id: 1163748:MARHY_RS04470
uniprot id: H8W705
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1163748:MARHY RS01435
gene id: 1163748:MARHY_RS01435
uniprot id: H8WCX2
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS01640
gene id: 1163748:MARHY_RS01640
uniprot id: H8WD12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1163748:MARHY RS18275
gene id: 1163748:MARHY_RS18275
uniprot id: H8WA75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1163748:MARHY RS16135
gene id: 1163748:MARHY_RS16135
uniprot id: H8W6N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS14430
gene id: 1163748:MARHY_RS14430
uniprot id: H8WE95
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS12240
gene id: 1163748:MARHY_RS12240
uniprot id: H8WAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1163748:MARHY RS09535
gene id: 1163748:MARHY_RS09535
uniprot id: H8W5R5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1163748:MARHY RS09735
gene id: 1163748:MARHY_RS09735
uniprot id: H8W5V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1163748:MARHY RS15300
gene id: 1163748:MARHY_RS15300
uniprot id: H8W586
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1163748:MARHY RS13620
gene id: 1163748:MARHY_RS13620
uniprot id: H8WCV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1163748:MARHY RS09985
gene id: 1163748:MARHY_RS09985
uniprot id: H8W6G8
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1163748:MARHY RS06365
gene id: 1163748:MARHY_RS06365
uniprot id: H8WAJ4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1163748:MARHY RS03450
gene id: 1163748:MARHY_RS03450
uniprot id: H8W5I1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1163748:MARHY RS04015
gene id: 1163748:MARHY_RS04015
uniprot id: H8W6A4
names: Similarity
messages: Belongs to the UPF0250 family.

1163748:MARHY RS09960
gene id: 1163748:MARHY_RS09960
uniprot id: H8W6G3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS15890
gene id: 1163748:MARHY_RS15890
uniprot id: H8W621
names: Similarity
messages: Belongs to the GARS family.

1163748:MARHY RS01515
gene id: 1163748:MARHY_RS01515
uniprot id: H8WCY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163748:MARHY RS14195
gene id: 1163748:MARHY_RS14195
uniprot id: H8WE48
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1163748:MARHY RS07190
gene id: 1163748:MARHY_RS07190
uniprot id: H8WCF5
names: Subcellular Location Annotation
messages: Cytoplasm

1163748:MARHY RS04110
gene id: 1163748:MARHY_RS04110
uniprot id: H8W6C4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1163748:MARHY RS04150
gene id: 1163748:MARHY_RS04150
uniprot id: H8W6U2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163748:MARHY RS07065
gene id: 1163748:MARHY_RS07065
uniprot id: H8WBW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1163748:MARHY RS12735
gene id: 1163748:MARHY_RS12735
uniprot id: H8WBE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1163748:MARHY RS15810
gene id: 1163748:MARHY_RS15810
uniprot id: H8W602
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1163748:MARHY RS03915
gene id: 1163748:MARHY_RS03915
uniprot id: H8W684
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1163748:MARHY RS06895
gene id: 1163748:MARHY_RS06895
uniprot id: H8WBT5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1163748:MARHY RS02585
gene id: 1163748:MARHY_RS02585
uniprot id: H8W437
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS02110
gene id: 1163748:MARHY_RS02110
uniprot id: H8WDR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1163748:MARHY RS01305
gene id: 1163748:MARHY_RS01305
uniprot id: H8WCD4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1163748:MARHY RS05255
gene id: 1163748:MARHY_RS05255
uniprot id: H8W8E2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1163748:MARHY RS15035
gene id: 1163748:MARHY_RS15035
uniprot id: H8W4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS05705
gene id: 1163748:MARHY_RS05705
uniprot id: H8W9K4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1163748:MARHY RS11165
gene id: 1163748:MARHY_RS11165
uniprot id: H8W8J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1163748:MARHY RS15305
gene id: 1163748:MARHY_RS15305
uniprot id: H8W587
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1163748:MARHY RS06000
gene id: 1163748:MARHY_RS06000
uniprot id: H8W9R7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1163748:MARHY RS16270
gene id: 1163748:MARHY_RS16270
uniprot id: H8W6R0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1163748:MARHY RS09740
gene id: 1163748:MARHY_RS09740
uniprot id: H8W5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS04500
gene id: 1163748:MARHY_RS04500
uniprot id: H8W712
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1163748:MARHY RS15295
gene id: 1163748:MARHY_RS15295
uniprot id: H8W585
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1163748:MARHY RS08420
gene id: 1163748:MARHY_RS08420
uniprot id: H8WEJ3
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1163748:MARHY RS12335
gene id: 1163748:MARHY_RS12335
uniprot id: H8WAP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS08300
gene id: 1163748:MARHY_RS08300
uniprot id: H8WE07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1163748:MARHY RS15850
gene id: 1163748:MARHY_RS15850
uniprot id: H8W613
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1163748:MARHY RS14860
gene id: 1163748:MARHY_RS14860
uniprot id: H8W4I8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1163748:MARHY RS10120
gene id: 1163748:MARHY_RS10120
uniprot id: H8W6J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1163748:MARHY RS10675
gene id: 1163748:MARHY_RS10675
uniprot id: H8W7T1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1163748:MARHY RS11240
gene id: 1163748:MARHY_RS11240
uniprot id: H8W8K9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS08455
gene id: 1163748:MARHY_RS08455
uniprot id: H8WEK1
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1163748:MARHY RS10325
gene id: 1163748:MARHY_RS10325
uniprot id: H8W746
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1163748:MARHY RS07245
gene id: 1163748:MARHY_RS07245
uniprot id: H8WCG6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1163748:MARHY RS08290
gene id: 1163748:MARHY_RS08290
uniprot id: H8WE05
names: Similarity
messages: Belongs to the TrpF family.

1163748:MARHY RS06865
gene id: 1163748:MARHY_RS06865
uniprot id: H8WBS9
names: Similarity
messages: Belongs to the fabD family.

1163748:MARHY RS13405
gene id: 1163748:MARHY_RS13405
uniprot id: H8WCQ8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1163748:MARHY RS08825
gene id: 1163748:MARHY_RS08825
uniprot id: H8W4C6
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1163748:MARHY RS10025
gene id: 1163748:MARHY_RS10025
uniprot id: H8W6H6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1163748:MARHY RS06230
gene id: 1163748:MARHY_RS06230
uniprot id: H8WAG6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1163748:MARHY RS11230
gene id: 1163748:MARHY_RS11230
uniprot id: H8W8K7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1163748:MARHY RS15220
gene id: 1163748:MARHY_RS15220
uniprot id: H8W4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1163748:MARHY RS08180
gene id: 1163748:MARHY_RS08180
uniprot id: H8WDY1
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1163748:MARHY RS06050
gene id: 1163748:MARHY_RS06050
uniprot id: H8WAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1163748:MARHY RS09875
gene id: 1163748:MARHY_RS09875
uniprot id: H8W6E5
names: Similarity
messages: Belongs to the acylphosphatase family.

1163748:MARHY RS18300
gene id: 1163748:MARHY_RS18300
uniprot id: H8WAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS03825
gene id: 1163748:MARHY_RS03825
uniprot id: H8W666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1163748:MARHY RS00145
gene id: 1163748:MARHY_RS00145
uniprot id: H8WAA7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1163748:MARHY RS11795
gene id: 1163748:MARHY_RS11795
uniprot id: H8W9T5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1163748:MARHY RS14705
gene id: 1163748:MARHY_RS14705
uniprot id: H8WEV9
names: Subcellular Location Annotation
messages: Nucleus

1163748:MARHY RS15960
gene id: 1163748:MARHY_RS15960
uniprot id: H8W637
names: Cofactor
messages: Can also use Mn(2+) ion.

1163748:MARHY RS04950
gene id: 1163748:MARHY_RS04950
uniprot id: H8W877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1163748:MARHY RS05900
gene id: 1163748:MARHY_RS05900
uniprot id: H8W9P6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1163748:MARHY RS15685
gene id: 1163748:MARHY_RS15685
uniprot id: H8W5X7
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1163748:MARHY RS15830
gene id: 1163748:MARHY_RS15830
uniprot id: H8W607
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1163748:MARHY RS01790
gene id: 1163748:MARHY_RS01790
uniprot id: H8WD42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1163748:MARHY RS02875
gene id: 1163748:MARHY_RS02875
uniprot id: H8W490
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1163748:MARHY RS14245
gene id: 1163748:MARHY_RS14245
uniprot id: H8WE58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS07840
gene id: 1163748:MARHY_RS07840
uniprot id: H8WD99
names: Similarity
messages: Belongs to the PrpF family.

1163748:MARHY RS03055
gene id: 1163748:MARHY_RS03055
uniprot id: H8W4T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1163748:MARHY RS00125
gene id: 1163748:MARHY_RS00125
uniprot id: H8WAA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1163748:MARHY RS08550
gene id: 1163748:MARHY_RS08550
uniprot id: H8WEM0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1163748:MARHY RS00235
gene id: 1163748:MARHY_RS00235
uniprot id: H8WAU3
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS18155
gene id: 1163748:MARHY_RS18155
uniprot id: H8WA50
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS06805
gene id: 1163748:MARHY_RS06805
uniprot id: H8WBR6
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS06790
gene id: 1163748:MARHY_RS06790
uniprot id: H8WBA1
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1163748:MARHY RS06980
gene id: 1163748:MARHY_RS06980
uniprot id: H8WBV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS05195
gene id: 1163748:MARHY_RS05195
uniprot id: H8W8C9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163748:MARHY RS03395
gene id: 1163748:MARHY_RS03395
uniprot id: H8W5H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS05970
gene id: 1163748:MARHY_RS05970
uniprot id: H8W9R1
names: Similarity
messages: Belongs to the glutamate synthase family.

1163748:MARHY RS12900
gene id: 1163748:MARHY_RS12900
uniprot id: H8WBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1163748:MARHY RS02490
gene id: 1163748:MARHY_RS02490
uniprot id: H8WEG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1163748:MARHY RS11810
gene id: 1163748:MARHY_RS11810
uniprot id: H8W9T8
names: Similarity
messages: Belongs to the ArsC family.

1163748:MARHY RS08680
gene id: 1163748:MARHY_RS08680
uniprot id: H8WEP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1163748:MARHY RS12710
gene id: 1163748:MARHY_RS12710
uniprot id: H8WBE2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS01340
gene id: 1163748:MARHY_RS01340
uniprot id: H8WCE1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1163748:MARHY RS14390
gene id: 1163748:MARHY_RS14390
uniprot id: H8WE87
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS09675
gene id: 1163748:MARHY_RS09675
uniprot id: H8W5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS15800
gene id: 1163748:MARHY_RS15800
uniprot id: H8W600
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1163748:MARHY RS04770
gene id: 1163748:MARHY_RS04770
uniprot id: H8W7M9
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1163748:MARHY RS09710
gene id: 1163748:MARHY_RS09710
uniprot id: H8W5V1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1163748:MARHY RS08350
gene id: 1163748:MARHY_RS08350
uniprot id: H8WEH8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163748:MARHY RS10715
gene id: 1163748:MARHY_RS10715
uniprot id: H8W7U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163748:MARHY RS02455
gene id: 1163748:MARHY_RS02455
uniprot id: H8WEF5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1163748:MARHY RS12475
gene id: 1163748:MARHY_RS12475
uniprot id: H8WAS5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1163748:MARHY RS09525
gene id: 1163748:MARHY_RS09525
uniprot id: H8W5R3
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1163748:MARHY RS13695
gene id: 1163748:MARHY_RS13695
uniprot id: H8WDD0
names: Similarity
messages: Belongs to the GST superfamily.

1163748:MARHY RS01490
gene id: 1163748:MARHY_RS01490
uniprot id: H8WCY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163748:MARHY RS15910
gene id: 1163748:MARHY_RS15910
uniprot id: H8W626
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163748:MARHY RS01585
gene id: 1163748:MARHY_RS01585
uniprot id: H8WD02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1163748:MARHY RS13325
gene id: 1163748:MARHY_RS13325
uniprot id: H8WCN9
names: Similarity
messages: Belongs to the YkuD family.

1163748:MARHY RS10125
gene id: 1163748:MARHY_RS10125
uniprot id: H8W6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1163748:MARHY RS07535
gene id: 1163748:MARHY_RS07535
uniprot id: H8WCM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1163748:MARHY RS18220
gene id: 1163748:MARHY_RS18220
uniprot id: H8WA64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1163748:MARHY RS16275
gene id: 1163748:MARHY_RS16275
uniprot id: H8W6R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1163748:MARHY RS04080
gene id: 1163748:MARHY_RS04080
uniprot id: H8W6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1163748:MARHY RS16120
gene id: 1163748:MARHY_RS16120
uniprot id: H8W6M9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1163748:MARHY RS07260
gene id: 1163748:MARHY_RS07260
uniprot id: H8WCG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1163748:MARHY RS02855
gene id: 1163748:MARHY_RS02855
uniprot id: H8W486
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1163748:MARHY RS15915
gene id: 1163748:MARHY_RS15915
uniprot id: H8W627
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1163748:MARHY RS13970
gene id: 1163748:MARHY_RS13970
uniprot id: H8WDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1163748:MARHY RS08240
gene id: 1163748:MARHY_RS08240
uniprot id: H8WDZ3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1163748:MARHY RS07610
gene id: 1163748:MARHY_RS07610
uniprot id: H8WD54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1163748:MARHY RS12300
gene id: 1163748:MARHY_RS12300
uniprot id: H8WAP1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1163748:MARHY RS08010
gene id: 1163748:MARHY_RS08010
uniprot id: H8WDU7
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1163748:MARHY RS12390
gene id: 1163748:MARHY_RS12390
uniprot id: H8WAQ9
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1163748:MARHY RS06890
gene id: 1163748:MARHY_RS06890
uniprot id: H8WBT4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1163748:MARHY RS11785
gene id: 1163748:MARHY_RS11785
uniprot id: H8W9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1163748:MARHY RS02740
gene id: 1163748:MARHY_RS02740
uniprot id: H8W462
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1163748:MARHY RS18075
gene id: 1163748:MARHY_RS18075
uniprot id: H8WA34
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1163748:MARHY RS06500
gene id: 1163748:MARHY_RS06500
uniprot id: H8WB43
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1163748:MARHY RS01875
gene id: 1163748:MARHY_RS01875
uniprot id: H8WDL9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1163748:MARHY RS11600
gene id: 1163748:MARHY_RS11600
uniprot id: H8W986
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1163748:MARHY RS13075
gene id: 1163748:MARHY_RS13075
uniprot id: H8WC25
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS13090
gene id: 1163748:MARHY_RS13090
uniprot id: H8WC29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1163748:MARHY RS13880
gene id: 1163748:MARHY_RS13880
uniprot id: H8WDG8
names: Subunit
messages: Homodimer.

1163748:MARHY RS16300
gene id: 1163748:MARHY_RS16300
uniprot id: H8W6R7
names: Similarity
messages: Belongs to the IucA/IucC family.

1163748:MARHY RS16875
gene id: 1163748:MARHY_RS16875
uniprot id: H8W805
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1163748:MARHY RS08675
gene id: 1163748:MARHY_RS08675
uniprot id: H8WEP6
names: Subcellular Location Annotation
messages: Membrane

1163748:MARHY RS11690
gene id: 1163748:MARHY_RS11690
uniprot id: H8W9A4
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1163748:MARHY RS08520
gene id: 1163748:MARHY_RS08520
uniprot id: H8WEL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1163748:MARHY RS11025
gene id: 1163748:MARHY_RS11025
uniprot id: H8W8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1163748:MARHY RS01325
gene id: 1163748:MARHY_RS01325
uniprot id: H8WCD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163748:MARHY RS07675
gene id: 1163748:MARHY_RS07675
uniprot id: H8WD65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1163748:MARHY RS03045
gene id: 1163748:MARHY_RS03045
uniprot id: H8W4T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1163748:MARHY RS07330
gene id: 1163748:MARHY_RS07330
uniprot id: H8WCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1163748:MARHY RS02815
gene id: 1163748:MARHY_RS02815
uniprot id: H8W478
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1163748:MARHY RS04330
gene id: 1163748:MARHY_RS04330
uniprot id: H8W6X7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1163748:MARHY RS11315
gene id: 1163748:MARHY_RS11315
uniprot id: H8W936
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1163748:MARHY RS01905
gene id: 1163748:MARHY_RS01905
uniprot id: H8WDM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1163748:MARHY RS04065
gene id: 1163748:MARHY_RS04065
uniprot id: H8W6B5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1163748:MARHY RS07170
gene id: 1163748:MARHY_RS07170
uniprot id: H8WBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane