1161099:CAPP RS01810
gene id: 1161099:CAPP_RS01810
uniprot id: A0A1N7JAK9
names: Similarity
messages: Belongs to the WXG100 family.

1161099:CAPP RS05555
gene id: 1161099:CAPP_RS05555
uniprot id: A0A1N7IVT6
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS09240
gene id: 1161099:CAPP_RS09240
uniprot id: A0A1N7K7D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1161099:CAPP RS02255
gene id: 1161099:CAPP_RS02255
uniprot id: A0A1N7JC40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1161099:CAPP RS03665
gene id: 1161099:CAPP_RS03665
uniprot id: A0A1N7JEC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS06460
gene id: 1161099:CAPP_RS06460
uniprot id: A0A1N7JGF1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1161099:CAPP RS05685
gene id: 1161099:CAPP_RS05685
uniprot id: A0A1N7IW10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS05345
gene id: 1161099:CAPP_RS05345
uniprot id: A0A1N7IV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS04805
gene id: 1161099:CAPP_RS04805
uniprot id: A0A1N7ITL7
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1161099:CAPP RS04855
gene id: 1161099:CAPP_RS04855
uniprot id: A0A1N7ITE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1161099:CAPP RS11085
gene id: 1161099:CAPP_RS11085
uniprot id: A0A1N7IQQ8
names: Similarity
messages: Belongs to the thioredoxin family.

1161099:CAPP RS03595
gene id: 1161099:CAPP_RS03595
uniprot id: A0A1N7JE08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1161099:CAPP RS09220
gene id: 1161099:CAPP_RS09220
uniprot id: A0A1N7K7I2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1161099:CAPP RS01700
gene id: 1161099:CAPP_RS01700
uniprot id: A0A1N7JAE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1161099:CAPP RS09000
gene id: 1161099:CAPP_RS09000
uniprot id: A0A1N7JPG9
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1161099:CAPP RS01815
gene id: 1161099:CAPP_RS01815
uniprot id: A0A1N7JAR7
names: Similarity
messages: Belongs to the WXG100 family.

1161099:CAPP RS11010
gene id: 1161099:CAPP_RS11010
uniprot id: A0A1N7IQW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1161099:CAPP RS05970
gene id: 1161099:CAPP_RS05970
uniprot id: A0A1N7IWY5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1161099:CAPP RS02000
gene id: 1161099:CAPP_RS02000
uniprot id: A0A1N7JBB7
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

1161099:CAPP RS09265
gene id: 1161099:CAPP_RS09265
uniprot id: A0A1N7K791
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1161099:CAPP RS00530
gene id: 1161099:CAPP_RS00530
uniprot id: A0A1N7IPC3
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS05660
gene id: 1161099:CAPP_RS05660
uniprot id: A0A1N7IW02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS04930
gene id: 1161099:CAPP_RS04930
uniprot id: A0A1N7ITL9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1161099:CAPP RS01865
gene id: 1161099:CAPP_RS01865
uniprot id: A0A1N7JAQ4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1161099:CAPP RS01540
gene id: 1161099:CAPP_RS01540
uniprot id: A0A1N7J9L6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1161099:CAPP RS08655
gene id: 1161099:CAPP_RS08655
uniprot id: A0A1N7JK91
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1161099:CAPP RS03195
gene id: 1161099:CAPP_RS03195
uniprot id: A0A1N7JXM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1161099:CAPP RS05590
gene id: 1161099:CAPP_RS05590
uniprot id: A0A1N7IVS4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1161099:CAPP RS03115
gene id: 1161099:CAPP_RS03115
uniprot id: A0A1N7JYB8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1161099:CAPP RS01190
gene id: 1161099:CAPP_RS01190
uniprot id: A0A1N7IMT9
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1161099:CAPP RS07985
gene id: 1161099:CAPP_RS07985
uniprot id: A0A1N7J0D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1161099:CAPP RS01855
gene id: 1161099:CAPP_RS01855
uniprot id: A0A1N7JAX8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS01150
gene id: 1161099:CAPP_RS01150
uniprot id: A0A1N7IMX0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1161099:CAPP RS07085
gene id: 1161099:CAPP_RS07085
uniprot id: A0A1N7J2W9
names: Similarity
messages: Belongs to the YciI family.

1161099:CAPP RS10200
gene id: 1161099:CAPP_RS10200
uniprot id: A0A1N7J8B1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1161099:CAPP RS04820
gene id: 1161099:CAPP_RS04820
uniprot id: A0A1N7ITI7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1161099:CAPP RS02655
gene id: 1161099:CAPP_RS02655
uniprot id: A0A1N7K322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1161099:CAPP RS09250
gene id: 1161099:CAPP_RS09250
uniprot id: A0A1N7K7C0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1161099:CAPP RS06520
gene id: 1161099:CAPP_RS06520
uniprot id: A0A1N7JFY5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1161099:CAPP RS10220
gene id: 1161099:CAPP_RS10220
uniprot id: A0A1N7J8J4
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS01375
gene id: 1161099:CAPP_RS01375
uniprot id: A0A1N7IM22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1161099:CAPP RS07155
gene id: 1161099:CAPP_RS07155
uniprot id: A0A1N7J2N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1161099:CAPP RS07195
gene id: 1161099:CAPP_RS07195
uniprot id: A0A1N7J2W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1161099:CAPP RS03890
gene id: 1161099:CAPP_RS03890
uniprot id: A0A1N7JV71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS00515
gene id: 1161099:CAPP_RS00515
uniprot id: A0A1N7IPM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1161099:CAPP RS10210
gene id: 1161099:CAPP_RS10210
uniprot id: A0A1N7J8B6
names: Similarity
messages: Belongs to the peptidase C56 family.

1161099:CAPP RS09550
gene id: 1161099:CAPP_RS09550
uniprot id: A0A1N7J677
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1161099:CAPP RS06620
gene id: 1161099:CAPP_RS06620
uniprot id: A0A1N7JFT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1161099:CAPP RS04890
gene id: 1161099:CAPP_RS04890
uniprot id: A0A1N7ITM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1161099:CAPP RS10000
gene id: 1161099:CAPP_RS10000
uniprot id: A0A1N7J7U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1161099:CAPP RS00025
gene id: 1161099:CAPP_RS00025
uniprot id: A0A1N7IQK5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1161099:CAPP RS01960
gene id: 1161099:CAPP_RS01960
uniprot id: A0A1N7JB42
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1161099:CAPP RS06315
gene id: 1161099:CAPP_RS06315
uniprot id: A0A1N7JGN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1161099:CAPP RS02115
gene id: 1161099:CAPP_RS02115
uniprot id: A0A1N7JBJ5
names: Similarity
messages: Belongs to the peptidase S11 family.

1161099:CAPP RS02095
gene id: 1161099:CAPP_RS02095
uniprot id: A0A1N7JBM2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1161099:CAPP RS04360
gene id: 1161099:CAPP_RS04360
uniprot id: A0A1N7K4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1161099:CAPP RS07980
gene id: 1161099:CAPP_RS07980
uniprot id: A0A1N7J068
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1161099:CAPP RS07125
gene id: 1161099:CAPP_RS07125
uniprot id: A0A1N7J2T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1161099:CAPP RS06250
gene id: 1161099:CAPP_RS06250
uniprot id: A0A1N7JGT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1161099:CAPP RS05565
gene id: 1161099:CAPP_RS05565
uniprot id: A0A1N7IVP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1161099:CAPP RS05605
gene id: 1161099:CAPP_RS05605
uniprot id: A0A1N7IVZ8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

1161099:CAPP RS04045
gene id: 1161099:CAPP_RS04045
uniprot id: A0A1N7JTY9
names: Similarity
messages: Belongs to the XFP family.

1161099:CAPP RS07400
gene id: 1161099:CAPP_RS07400
uniprot id: A0A1N7J228
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1161099:CAPP RS07645
gene id: 1161099:CAPP_RS07645
uniprot id: A0A1N7J142
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1161099:CAPP RS01670
gene id: 1161099:CAPP_RS01670
uniprot id: A0A1N7JA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS07500
gene id: 1161099:CAPP_RS07500
uniprot id: A0A1N7J1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS00520
gene id: 1161099:CAPP_RS00520
uniprot id: A0A1N7IPB6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1161099:CAPP RS00700
gene id: 1161099:CAPP_RS00700
uniprot id: A0A1N7IP92
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS02585
gene id: 1161099:CAPP_RS02585
uniprot id: A0A1N7K2K2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1161099:CAPP RS02170
gene id: 1161099:CAPP_RS02170
uniprot id: A0A1N7JBI8
names: Similarity
messages: Belongs to the citrate synthase family.

1161099:CAPP RS08155
gene id: 1161099:CAPP_RS08155
uniprot id: A0A1N7IZJ8
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1161099:CAPP RS01445
gene id: 1161099:CAPP_RS01445
uniprot id: A0A1N7ILY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1161099:CAPP RS00200
gene id: 1161099:CAPP_RS00200
uniprot id: A0A1N7IPZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1161099:CAPP RS07415
gene id: 1161099:CAPP_RS07415
uniprot id: A0A1N7J1Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1161099:CAPP RS03945
gene id: 1161099:CAPP_RS03945
uniprot id: A0A1N7JV45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1161099:CAPP RS02690
gene id: 1161099:CAPP_RS02690
uniprot id: A0A1N7KF97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1161099:CAPP RS10405
gene id: 1161099:CAPP_RS10405
uniprot id: A0A1N7JIB0
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS00905
gene id: 1161099:CAPP_RS00905
uniprot id: A0A1N7INF8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1161099:CAPP RS11100
gene id: 1161099:CAPP_RS11100
uniprot id: A0A1N7IQG0
names: Similarity
messages: Belongs to the ParB family.

1161099:CAPP RS04815
gene id: 1161099:CAPP_RS04815
uniprot id: A0A1N7ITA8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS07750
gene id: 1161099:CAPP_RS07750
uniprot id: A0A1N7J0W6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1161099:CAPP RS01435
gene id: 1161099:CAPP_RS01435
uniprot id: A0A1N7ILZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1161099:CAPP RS03180
gene id: 1161099:CAPP_RS03180
uniprot id: A0A1N7JY30
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

1161099:CAPP RS07955
gene id: 1161099:CAPP_RS07955
uniprot id: A0A1N7J0J3
names: Similarity
messages: Belongs to the peptidase C40 family.

1161099:CAPP RS04390
gene id: 1161099:CAPP_RS04390
uniprot id: A0A1N7K4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1161099:CAPP RS10710
gene id: 1161099:CAPP_RS10710
uniprot id: A0A1N7JH57
names: Similarity
messages: Belongs to the universal stress protein A family.

1161099:CAPP RS05525
gene id: 1161099:CAPP_RS05525
uniprot id: A0A1N7IVI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS05615
gene id: 1161099:CAPP_RS05615
uniprot id: A0A1N7IVV6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1161099:CAPP RS05030
gene id: 1161099:CAPP_RS05030
uniprot id: A0A1N7ITY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS06275
gene id: 1161099:CAPP_RS06275
uniprot id: A0A1N7JGR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1161099:CAPP RS01560
gene id: 1161099:CAPP_RS01560
uniprot id: A0A1N7J9R1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1161099:CAPP RS07925
gene id: 1161099:CAPP_RS07925
uniprot id: A0A1N7J0A8
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1161099:CAPP RS10875
gene id: 1161099:CAPP_RS10875
uniprot id: A0A1N7IQZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1161099:CAPP RS03560
gene id: 1161099:CAPP_RS03560
uniprot id: A0A1N7JE62
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1161099:CAPP RS06025
gene id: 1161099:CAPP_RS06025
uniprot id: A0A1N7IX62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1161099:CAPP RS09815
gene id: 1161099:CAPP_RS09815
uniprot id: A0A1N7J774
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1161099:CAPP RS04400
gene id: 1161099:CAPP_RS04400
uniprot id: A0A1N7K4P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1161099:CAPP RS05290
gene id: 1161099:CAPP_RS05290
uniprot id: A0A1N7IUN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1161099:CAPP RS04075
gene id: 1161099:CAPP_RS04075
uniprot id: A0A1N7JU25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS03750
gene id: 1161099:CAPP_RS03750
uniprot id: A0A1N7JER4
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS10865
gene id: 1161099:CAPP_RS10865
uniprot id: A0A1N7IR02
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1161099:CAPP RS07185
gene id: 1161099:CAPP_RS07185
uniprot id: A0A1N7J2Q9
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS01795
gene id: 1161099:CAPP_RS01795
uniprot id: A0A1N7JAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

1161099:CAPP RS00040
gene id: 1161099:CAPP_RS00040
uniprot id: A0A1N7IQJ3
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1161099:CAPP RS08270
gene id: 1161099:CAPP_RS08270
uniprot id: A0A1N7JMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1161099:CAPP RS07625
gene id: 1161099:CAPP_RS07625
uniprot id: A0A1N7J1G8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1161099:CAPP RS02545
gene id: 1161099:CAPP_RS02545
uniprot id: A0A1N7K1Z3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1161099:CAPP RS09915
gene id: 1161099:CAPP_RS09915
uniprot id: A0A1N7J7E0
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS06480
gene id: 1161099:CAPP_RS06480
uniprot id: A0A1N7JGD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS07165
gene id: 1161099:CAPP_RS07165
uniprot id: A0A1N7J2T4
names: Similarity
messages: Belongs to the ribF family.

1161099:CAPP RS01305
gene id: 1161099:CAPP_RS01305
uniprot id: A0A1N7IM72
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1161099:CAPP RS06375
gene id: 1161099:CAPP_RS06375
uniprot id: A0A1N7JGN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1161099:CAPP RS09650
gene id: 1161099:CAPP_RS09650
uniprot id: A0A1N7J697
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1161099:CAPP RS07455
gene id: 1161099:CAPP_RS07455
uniprot id: A0A1N7J239
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1161099:CAPP RS02910
gene id: 1161099:CAPP_RS02910
uniprot id: A0A1N7KAX4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1161099:CAPP RS07885
gene id: 1161099:CAPP_RS07885
uniprot id: A0A1N7J0Q0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1161099:CAPP RS04785
gene id: 1161099:CAPP_RS04785
uniprot id: A0A1N7ITC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1161099:CAPP RS01615
gene id: 1161099:CAPP_RS01615
uniprot id: A0A1N7J9Y1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

1161099:CAPP RS01730
gene id: 1161099:CAPP_RS01730
uniprot id: A0A1N7JAE6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1161099:CAPP RS03215
gene id: 1161099:CAPP_RS03215
uniprot id: A0A1N7JXJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1161099:CAPP RS01530
gene id: 1161099:CAPP_RS01530
uniprot id: A0A1N7J9J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1161099:CAPP RS06515
gene id: 1161099:CAPP_RS06515
uniprot id: A0A1N7JG20
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1161099:CAPP RS01735
gene id: 1161099:CAPP_RS01735
uniprot id: A0A1N7JAI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1161099:CAPP RS07115
gene id: 1161099:CAPP_RS07115
uniprot id: A0A1N7J2Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1161099:CAPP RS03785
gene id: 1161099:CAPP_RS03785
uniprot id: A0A1N7JEX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS03200
gene id: 1161099:CAPP_RS03200
uniprot id: A0A1N7JXL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1161099:CAPP RS06415
gene id: 1161099:CAPP_RS06415
uniprot id: A0A1N7JGK9
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1161099:CAPP RS04305
gene id: 1161099:CAPP_RS04305
uniprot id: A0A1N7K428
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS10055
gene id: 1161099:CAPP_RS10055
uniprot id: A0A1N7J7Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1161099:CAPP RS02765
gene id: 1161099:CAPP_RS02765
uniprot id: A0A1N7K9R2
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1161099:CAPP RS01070
gene id: 1161099:CAPP_RS01070
uniprot id: A0A1N7IMX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1161099:CAPP RS08410
gene id: 1161099:CAPP_RS08410
uniprot id: A0A1N7JLT4
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS09520
gene id: 1161099:CAPP_RS09520
uniprot id: A0A1N7J5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1161099:CAPP RS06970
gene id: 1161099:CAPP_RS06970
uniprot id: A0A1N7J3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1161099:CAPP RS07730
gene id: 1161099:CAPP_RS07730
uniprot id: A0A1N7J0X3
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS06795
gene id: 1161099:CAPP_RS06795
uniprot id: A0A1N7J481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1161099:CAPP RS07840
gene id: 1161099:CAPP_RS07840
uniprot id: A0A1N7J0J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS05810
gene id: 1161099:CAPP_RS05810
uniprot id: A0A1N7IWS1
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS09740
gene id: 1161099:CAPP_RS09740
uniprot id: A0A1N7J6P5
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS10245
gene id: 1161099:CAPP_RS10245
uniprot id: A0A1N7J8A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1161099:CAPP RS01125
gene id: 1161099:CAPP_RS01125
uniprot id: A0A1N7IN09
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1161099:CAPP RS06655
gene id: 1161099:CAPP_RS06655
uniprot id: A0A1N7JFP9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1161099:CAPP RS10265
gene id: 1161099:CAPP_RS10265
uniprot id: A0A1N7J8Q0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1161099:CAPP RS03220
gene id: 1161099:CAPP_RS03220
uniprot id: A0A1N7JXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1161099:CAPP RS00335
gene id: 1161099:CAPP_RS00335
uniprot id: A0A1N7IPQ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1161099:CAPP RS10580
gene id: 1161099:CAPP_RS10580
uniprot id: A0A1N7JHW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1161099:CAPP RS00620
gene id: 1161099:CAPP_RS00620
uniprot id: A0A1N7IPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1161099:CAPP RS02800
gene id: 1161099:CAPP_RS02800
uniprot id: A0A1N7KA92
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS01990
gene id: 1161099:CAPP_RS01990
uniprot id: A0A1N7JB53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1161099:CAPP RS07825
gene id: 1161099:CAPP_RS07825
uniprot id: A0A1N7J140
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1161099:CAPP RS06555
gene id: 1161099:CAPP_RS06555
uniprot id: A0A1N7JG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1161099:CAPP RS10805
gene id: 1161099:CAPP_RS10805
uniprot id: A0A1N7IR27
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS09165
gene id: 1161099:CAPP_RS09165
uniprot id: A0A1N7K8B8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1161099:CAPP RS02490
gene id: 1161099:CAPP_RS02490
uniprot id: A0A1N7K1F8
names: Similarity
messages: Belongs to the thymidylate kinase family.

1161099:CAPP RS05540
gene id: 1161099:CAPP_RS05540
uniprot id: A0A1N7IVL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1161099:CAPP RS01765
gene id: 1161099:CAPP_RS01765
uniprot id: A0A1N7JAF1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1161099:CAPP RS09765
gene id: 1161099:CAPP_RS09765
uniprot id: A0A1N7J6T9
names: Similarity
messages: Belongs to the pantothenate synthetase family.

1161099:CAPP RS07835
gene id: 1161099:CAPP_RS07835
uniprot id: A0A1N7J0M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1161099:CAPP RS06505
gene id: 1161099:CAPP_RS06505
uniprot id: A0A1N7JGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1161099:CAPP RS06405
gene id: 1161099:CAPP_RS06405
uniprot id: A0A1N7JGF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1161099:CAPP RS07805
gene id: 1161099:CAPP_RS07805
uniprot id: A0A1N7J0Q4
names: Similarity
messages: Belongs to the YggT family.

1161099:CAPP RS10240
gene id: 1161099:CAPP_RS10240
uniprot id: A0A1N7J8E3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1161099:CAPP RS08145
gene id: 1161099:CAPP_RS08145
uniprot id: A0A1N7IZM2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1161099:CAPP RS03340
gene id: 1161099:CAPP_RS03340
uniprot id: A0A1N7JD57
names: Similarity
messages: Belongs to the FPG family.

1161099:CAPP RS01195
gene id: 1161099:CAPP_RS01195
uniprot id: A0A1N7IMI4
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1161099:CAPP RS03660
gene id: 1161099:CAPP_RS03660
uniprot id: A0A1N7JEG2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS09275
gene id: 1161099:CAPP_RS09275
uniprot id: A0A1N7K735
names: Similarity
messages: Belongs to the fructosamine kinase family.

1161099:CAPP RS09440
gene id: 1161099:CAPP_RS09440
uniprot id: A0A1N7J5I7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1161099:CAPP RS02760
gene id: 1161099:CAPP_RS02760
uniprot id: A0A1N7KA11
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1161099:CAPP RS07330
gene id: 1161099:CAPP_RS07330
uniprot id: A0A1N7J2B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1161099:CAPP RS02025
gene id: 1161099:CAPP_RS02025
uniprot id: A0A1N7JBD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS02570
gene id: 1161099:CAPP_RS02570
uniprot id: A0A1N7K1Y6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1161099:CAPP RS01715
gene id: 1161099:CAPP_RS01715
uniprot id: A0A1N7JA80
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1161099:CAPP RS05990
gene id: 1161099:CAPP_RS05990
uniprot id: A0A1N7IX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1161099:CAPP RS05165
gene id: 1161099:CAPP_RS05165
uniprot id: A0A1N7IUK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS02550
gene id: 1161099:CAPP_RS02550
uniprot id: A0A1N7K1U6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1161099:CAPP RS06900
gene id: 1161099:CAPP_RS06900
uniprot id: A0A1N7J3V1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1161099:CAPP RS07675
gene id: 1161099:CAPP_RS07675
uniprot id: A0A1N7J181
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1161099:CAPP RS03725
gene id: 1161099:CAPP_RS03725
uniprot id: A0A1N7JEH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1161099:CAPP RS05020
gene id: 1161099:CAPP_RS05020
uniprot id: A0A1N7ITX4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1161099:CAPP RS09585
gene id: 1161099:CAPP_RS09585
uniprot id: A0A1N7J673
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1161099:CAPP RS07435
gene id: 1161099:CAPP_RS07435
uniprot id: A0A1N7J261
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1161099:CAPP RS05125
gene id: 1161099:CAPP_RS05125
uniprot id: A0A1N7IUJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS08850
gene id: 1161099:CAPP_RS08850
uniprot id: A0A1N7JQK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1161099:CAPP RS09635
gene id: 1161099:CAPP_RS09635
uniprot id: A0A1N7J676
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1161099:CAPP RS10890
gene id: 1161099:CAPP_RS10890
uniprot id: A0A1N7IQY6
names: Similarity
messages: Belongs to the FPG family.

1161099:CAPP RS07120
gene id: 1161099:CAPP_RS07120
uniprot id: A0A1N7J2Y6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS06160
gene id: 1161099:CAPP_RS06160
uniprot id: A0A1N7IXS8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1161099:CAPP RS08565
gene id: 1161099:CAPP_RS08565
uniprot id: A0A1N7JKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS02735
gene id: 1161099:CAPP_RS02735
uniprot id: A0A1N7KEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1161099:CAPP RS01205
gene id: 1161099:CAPP_RS01205
uniprot id: A0A1N7IMS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS09800
gene id: 1161099:CAPP_RS09800
uniprot id: A0A1N7J729
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1161099:CAPP RS01145
gene id: 1161099:CAPP_RS01145
uniprot id: A0A1N7IMY4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1161099:CAPP RS10080
gene id: 1161099:CAPP_RS10080
uniprot id: A0A1N7J7X8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1161099:CAPP RS10940
gene id: 1161099:CAPP_RS10940
uniprot id: A0A1N7IQU0
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS09090
gene id: 1161099:CAPP_RS09090
uniprot id: A0A1N7K8I2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1161099:CAPP RS05945
gene id: 1161099:CAPP_RS05945
uniprot id: A0A1N7IWW7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1161099:CAPP RS07025
gene id: 1161099:CAPP_RS07025
uniprot id: A0A1N7J338
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1161099:CAPP RS06855
gene id: 1161099:CAPP_RS06855
uniprot id: A0A1N7J400
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1161099:CAPP RS05305
gene id: 1161099:CAPP_RS05305
uniprot id: A0A1N7IUS5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1161099:CAPP RS03310
gene id: 1161099:CAPP_RS03310
uniprot id: A0A1N7JD48
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1161099:CAPP RS06125
gene id: 1161099:CAPP_RS06125
uniprot id: A0A1N7IXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS09710
gene id: 1161099:CAPP_RS09710
uniprot id: A0A1N7J6L9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1161099:CAPP RS10895
gene id: 1161099:CAPP_RS10895
uniprot id: A0A1N7IR59
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1161099:CAPP RS09255
gene id: 1161099:CAPP_RS09255
uniprot id: A0A1N7K778
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1161099:CAPP RS05835
gene id: 1161099:CAPP_RS05835
uniprot id: A0A1N7IWV5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1161099:CAPP RS06080
gene id: 1161099:CAPP_RS06080
uniprot id: A0A1N7IXA6
names: Similarity
messages: Belongs to the peptidase C40 family.

1161099:CAPP RS03950
gene id: 1161099:CAPP_RS03950
uniprot id: A0A1N7JUX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1161099:CAPP RS05830
gene id: 1161099:CAPP_RS05830
uniprot id: A0A1N7IWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1161099:CAPP RS06310
gene id: 1161099:CAPP_RS06310
uniprot id: A0A1N7JGU1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1161099:CAPP RS09300
gene id: 1161099:CAPP_RS09300
uniprot id: A0A1N7K6Z8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1161099:CAPP RS06030
gene id: 1161099:CAPP_RS06030
uniprot id: A0A1N7IX67
names: Similarity
messages: Belongs to the UPF0098 family.

1161099:CAPP RS00870
gene id: 1161099:CAPP_RS00870
uniprot id: A0A1N7INK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1161099:CAPP RS06805
gene id: 1161099:CAPP_RS06805
uniprot id: A0A1N7J3V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

1161099:CAPP RS01870
gene id: 1161099:CAPP_RS01870
uniprot id: A0A1N7JAU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1161099:CAPP RS06550
gene id: 1161099:CAPP_RS06550
uniprot id: A0A1N7JG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1161099:CAPP RS10705
gene id: 1161099:CAPP_RS10705
uniprot id: A0A1N7JHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1161099:CAPP RS01315
gene id: 1161099:CAPP_RS01315
uniprot id: A0A1N7IM94
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1161099:CAPP RS08050
gene id: 1161099:CAPP_RS08050
uniprot id: A0A1N7IZY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1161099:CAPP RS08530
gene id: 1161099:CAPP_RS08530
uniprot id: A0A1N7JKW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1161099:CAPP RS07035
gene id: 1161099:CAPP_RS07035
uniprot id: A0A1N7J349
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1161099:CAPP RS07800
gene id: 1161099:CAPP_RS07800
uniprot id: A0A1N7J0Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1161099:CAPP RS00940
gene id: 1161099:CAPP_RS00940
uniprot id: A0A1N7INA2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1161099:CAPP RS04800
gene id: 1161099:CAPP_RS04800
uniprot id: A0A1N7ITA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1161099:CAPP RS05610
gene id: 1161099:CAPP_RS05610
uniprot id: A0A1N7IVV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1161099:CAPP RS10540
gene id: 1161099:CAPP_RS10540
uniprot id: A0A1N7JHX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1161099:CAPP RS10945
gene id: 1161099:CAPP_RS10945
uniprot id: A0A1N7IQS6
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS00295
gene id: 1161099:CAPP_RS00295
uniprot id: A0A1N7IPT6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1161099:CAPP RS03420
gene id: 1161099:CAPP_RS03420
uniprot id: A0A1N7JDL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1161099:CAPP RS02885
gene id: 1161099:CAPP_RS02885
uniprot id: A0A1N7KAP7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1161099:CAPP RS00160
gene id: 1161099:CAPP_RS00160
uniprot id: A0A1N7IQ31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1161099:CAPP RS04085
gene id: 1161099:CAPP_RS04085
uniprot id: A0A1N7JTN9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1161099:CAPP RS07395
gene id: 1161099:CAPP_RS07395
uniprot id: A0A1N7J1Y8
names: Similarity
messages: Belongs to the DprA/Smf family.

1161099:CAPP RS06220
gene id: 1161099:CAPP_RS06220
uniprot id: A0A1N7IXS9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS03860
gene id: 1161099:CAPP_RS03860
uniprot id: A0A1N7JVG7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1161099:CAPP RS07510
gene id: 1161099:CAPP_RS07510
uniprot id: A0A1N7J1S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1161099:CAPP RS10995
gene id: 1161099:CAPP_RS10995
uniprot id: A0A1N7IQR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS10645
gene id: 1161099:CAPP_RS10645
uniprot id: A0A1N7JHI6
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS03515
gene id: 1161099:CAPP_RS03515
uniprot id: A0A1N7JDX2
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS06150
gene id: 1161099:CAPP_RS06150
uniprot id: A0A1N7IXR7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1161099:CAPP RS07215
gene id: 1161099:CAPP_RS07215
uniprot id: A0A1N7J2J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1161099:CAPP RS00595
gene id: 1161099:CAPP_RS00595
uniprot id: A0A1N7IP75
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS09135
gene id: 1161099:CAPP_RS09135
uniprot id: A0A1N7K857
names: Similarity
messages: Belongs to the LOG family.

1161099:CAPP RS01355
gene id: 1161099:CAPP_RS01355
uniprot id: A0A1N7IM76
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1161099:CAPP RS09660
gene id: 1161099:CAPP_RS09660
uniprot id: A0A1N7J6N3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS00935
gene id: 1161099:CAPP_RS00935
uniprot id: A0A1N7IN94
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1161099:CAPP RS01695
gene id: 1161099:CAPP_RS01695
uniprot id: A0A1N7JA60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1161099:CAPP RS06320
gene id: 1161099:CAPP_RS06320
uniprot id: A0A1N7JGF8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1161099:CAPP RS05100
gene id: 1161099:CAPP_RS05100
uniprot id: A0A1N7IU58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS05330
gene id: 1161099:CAPP_RS05330
uniprot id: A0A1N7IUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1161099:CAPP RS09180
gene id: 1161099:CAPP_RS09180
uniprot id: A0A1N7K7V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1161099:CAPP RS05365
gene id: 1161099:CAPP_RS05365
uniprot id: A0A1N7IUX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS06490
gene id: 1161099:CAPP_RS06490
uniprot id: A0A1N7JFZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1161099:CAPP RS06510
gene id: 1161099:CAPP_RS06510
uniprot id: A0A1N7JFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1161099:CAPP RS05620
gene id: 1161099:CAPP_RS05620
uniprot id: A0A1N7IW18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1161099:CAPP RS01185
gene id: 1161099:CAPP_RS01185
uniprot id: A0A1N7IMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1161099:CAPP RS01745
gene id: 1161099:CAPP_RS01745
uniprot id: A0A1N7JAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1161099:CAPP RS04605
gene id: 1161099:CAPP_RS04605
uniprot id: A0A1N7KDI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS01705
gene id: 1161099:CAPP_RS01705
uniprot id: A0A1N7JA67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1161099:CAPP RS03700
gene id: 1161099:CAPP_RS03700
uniprot id: A0A1N7JEM3
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS08925
gene id: 1161099:CAPP_RS08925
uniprot id: A0A1N7JQ22
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1161099:CAPP RS07040
gene id: 1161099:CAPP_RS07040
uniprot id: A0A1N7J331
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1161099:CAPP RS00705
gene id: 1161099:CAPP_RS00705
uniprot id: A0A1N7INY5
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS05855
gene id: 1161099:CAPP_RS05855
uniprot id: A0A1N7IWR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS10550
gene id: 1161099:CAPP_RS10550
uniprot id: A0A1N7JHT7
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1161099:CAPP RS09355
gene id: 1161099:CAPP_RS09355
uniprot id: A0A1N7KGQ8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1161099:CAPP RS10010
gene id: 1161099:CAPP_RS10010
uniprot id: A0A1N7J7K9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1161099:CAPP RS08990
gene id: 1161099:CAPP_RS08990
uniprot id: A0A1N7JPK1
names: Similarity
messages: Belongs to the peptidase M1 family.

1161099:CAPP RS09830
gene id: 1161099:CAPP_RS09830
uniprot id: A0A1N7J6W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1161099:CAPP RS02070
gene id: 1161099:CAPP_RS02070
uniprot id: A0A1N7JBE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1161099:CAPP RS03480
gene id: 1161099:CAPP_RS03480
uniprot id: A0A1N7JDN3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1161099:CAPP RS11125
gene id: 1161099:CAPP_RS11125
uniprot id: A0A1N7IQF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1161099:CAPP RS03240
gene id: 1161099:CAPP_RS03240
uniprot id: A0A1N7JXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1161099:CAPP RS01595
gene id: 1161099:CAPP_RS01595
uniprot id: A0A1N7JA22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1161099:CAPP RS01010
gene id: 1161099:CAPP_RS01010
uniprot id: A0A1N7IN43
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1161099:CAPP RS06950
gene id: 1161099:CAPP_RS06950
uniprot id: A0A1N7J3C0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1161099:CAPP RS02905
gene id: 1161099:CAPP_RS02905
uniprot id: A0A1N7KAV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1161099:CAPP RS05010
gene id: 1161099:CAPP_RS05010
uniprot id: A0A1N7IU34
names: Similarity
messages: Belongs to the cytochrome P450 family.

1161099:CAPP RS01495
gene id: 1161099:CAPP_RS01495
uniprot id: A0A1N7J9Q7
names: Similarity
messages: Belongs to the asp23 family.

1161099:CAPP RS09910
gene id: 1161099:CAPP_RS09910
uniprot id: A0A1N7J787
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS08055
gene id: 1161099:CAPP_RS08055
uniprot id: A0A1N7IZV7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS06300
gene id: 1161099:CAPP_RS06300
uniprot id: A0A1N7JGV3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1161099:CAPP RS09320
gene id: 1161099:CAPP_RS09320
uniprot id: A0A1N7K6R4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1161099:CAPP RS05730
gene id: 1161099:CAPP_RS05730
uniprot id: A0A1N7IW86
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1161099:CAPP RS06820
gene id: 1161099:CAPP_RS06820
uniprot id: A0A1N7J3U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1161099:CAPP RS10280
gene id: 1161099:CAPP_RS10280
uniprot id: A0A1N7J8V0
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS03315
gene id: 1161099:CAPP_RS03315
uniprot id: A0A1N7JD45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS03645
gene id: 1161099:CAPP_RS03645
uniprot id: A0A1N7JEG3
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS07380
gene id: 1161099:CAPP_RS07380
uniprot id: A0A1N7J2E1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1161099:CAPP RS01985
gene id: 1161099:CAPP_RS01985
uniprot id: A0A1N7JAZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1161099:CAPP RS06060
gene id: 1161099:CAPP_RS06060
uniprot id: A0A1N7IXB7
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS05950
gene id: 1161099:CAPP_RS05950
uniprot id: A0A1N7IX20
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1161099:CAPP RS06105
gene id: 1161099:CAPP_RS06105
uniprot id: A0A1N7IXC0
names: Similarity
messages: Belongs to the UPF0237 family.

1161099:CAPP RS05690
gene id: 1161099:CAPP_RS05690
uniprot id: A0A1N7IW20
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1161099:CAPP RS04080
gene id: 1161099:CAPP_RS04080
uniprot id: A0A1N7JTM6
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS10695
gene id: 1161099:CAPP_RS10695
uniprot id: A0A1N7JHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1161099:CAPP RS04585
gene id: 1161099:CAPP_RS04585
uniprot id: A0A1N7KDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1161099:CAPP RS06470
gene id: 1161099:CAPP_RS06470
uniprot id: A0A1N7JG77
names: Similarity
messages: Belongs to the peptidase M24B family.

1161099:CAPP RS05545
gene id: 1161099:CAPP_RS05545
uniprot id: A0A1N7IVV9
names: Similarity
messages: Belongs to the universal stress protein A family.

1161099:CAPP RS08715
gene id: 1161099:CAPP_RS08715
uniprot id: A0A1N7JK00
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS06090
gene id: 1161099:CAPP_RS06090
uniprot id: A0A1N7IXB1
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1161099:CAPP RS03140
gene id: 1161099:CAPP_RS03140
uniprot id: A0A1N7JY33
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1161099:CAPP RS01725
gene id: 1161099:CAPP_RS01725
uniprot id: A0A1N7JAC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1161099:CAPP RS05155
gene id: 1161099:CAPP_RS05155
uniprot id: A0A1N7IUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1161099:CAPP RS09030
gene id: 1161099:CAPP_RS09030
uniprot id: A0A1N7JPD7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1161099:CAPP RS05085
gene id: 1161099:CAPP_RS05085
uniprot id: A0A1N7IUB2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1161099:CAPP RS05115
gene id: 1161099:CAPP_RS05115
uniprot id: A0A1N7IUJ2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1161099:CAPP RS05955
gene id: 1161099:CAPP_RS05955
uniprot id: A0A1N7IWY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1161099:CAPP RS04415
gene id: 1161099:CAPP_RS04415
uniprot id: A0A1N7K514
names: Similarity
messages: Belongs to the LOG family.

1161099:CAPP RS03485
gene id: 1161099:CAPP_RS03485
uniprot id: A0A1N7JDQ1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1161099:CAPP RS01270
gene id: 1161099:CAPP_RS01270
uniprot id: A0A1N7IMB2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS03425
gene id: 1161099:CAPP_RS03425
uniprot id: A0A1N7JDG9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1161099:CAPP RS01535
gene id: 1161099:CAPP_RS01535
uniprot id: A0A1N7J9K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1161099:CAPP RS03570
gene id: 1161099:CAPP_RS03570
uniprot id: A0A1N7JE69
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1161099:CAPP RS00670
gene id: 1161099:CAPP_RS00670
uniprot id: A0A1N7IP21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS05900
gene id: 1161099:CAPP_RS05900
uniprot id: A0A1N7IWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1161099:CAPP RS02075
gene id: 1161099:CAPP_RS02075
uniprot id: A0A1N7JBK1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1161099:CAPP RS00425
gene id: 1161099:CAPP_RS00425
uniprot id: A0A1N7IPK6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1161099:CAPP RS07325
gene id: 1161099:CAPP_RS07325
uniprot id: A0A1N7J279
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1161099:CAPP RS08830
gene id: 1161099:CAPP_RS08830
uniprot id: A0A1N7JQR0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1161099:CAPP RS02165
gene id: 1161099:CAPP_RS02165
uniprot id: A0A1N7JBT1
names: Similarity
messages: Belongs to the PrpD family.

1161099:CAPP RS05745
gene id: 1161099:CAPP_RS05745
uniprot id: A0A1N7IW87
names: Subcellular Location Annotation
messages: Secreted

1161099:CAPP RS00245
gene id: 1161099:CAPP_RS00245
uniprot id: A0A1N7IPX0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1161099:CAPP RS07050
gene id: 1161099:CAPP_RS07050
uniprot id: A0A1N7J3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1161099:CAPP RS02845
gene id: 1161099:CAPP_RS02845
uniprot id: A0A1N7KAD3
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS01565
gene id: 1161099:CAPP_RS01565
uniprot id: A0A1N7J9N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1161099:CAPP RS06325
gene id: 1161099:CAPP_RS06325
uniprot id: A0A1N7JGK7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1161099:CAPP RS00665
gene id: 1161099:CAPP_RS00665
uniprot id: A0A1N7IP18
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1161099:CAPP RS08995
gene id: 1161099:CAPP_RS08995
uniprot id: A0A1N7JPN9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1161099:CAPP RS09720
gene id: 1161099:CAPP_RS09720
uniprot id: A0A1N7J6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1161099:CAPP RS03410
gene id: 1161099:CAPP_RS03410
uniprot id: A0A1N7JDG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1161099:CAPP RS08110
gene id: 1161099:CAPP_RS08110
uniprot id: A0A1N7IZT3
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS08835
gene id: 1161099:CAPP_RS08835
uniprot id: A0A1N7JQQ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1161099:CAPP RS08595
gene id: 1161099:CAPP_RS08595
uniprot id: A0A1N7JKH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1161099:CAPP RS01450
gene id: 1161099:CAPP_RS01450
uniprot id: A0A1N7ILX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1161099:CAPP RS02795
gene id: 1161099:CAPP_RS02795
uniprot id: A0A1N7KA16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1161099:CAPP RS07460
gene id: 1161099:CAPP_RS07460
uniprot id: A0A1N7J1W5
names: Similarity
messages: Belongs to the P(II) protein family.

1161099:CAPP RS01280
gene id: 1161099:CAPP_RS01280
uniprot id: A0A1N7IMA0
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS00195
gene id: 1161099:CAPP_RS00195
uniprot id: A0A1N7IQ28
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1161099:CAPP RS09695
gene id: 1161099:CAPP_RS09695
uniprot id: A0A1N7J6J8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1161099:CAPP RS09920
gene id: 1161099:CAPP_RS09920
uniprot id: A0A1N7J7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS07850
gene id: 1161099:CAPP_RS07850
uniprot id: A0A1N7J0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1161099:CAPP RS09545
gene id: 1161099:CAPP_RS09545
uniprot id: A0A1N7J634
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1161099:CAPP RS08445
gene id: 1161099:CAPP_RS08445
uniprot id: A0A1N7JLL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1161099:CAPP RS07815
gene id: 1161099:CAPP_RS07815
uniprot id: A0A1N7J0P6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1161099:CAPP RS01425
gene id: 1161099:CAPP_RS01425
uniprot id: A0A1N7ILX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1161099:CAPP RS00710
gene id: 1161099:CAPP_RS00710
uniprot id: A0A1N7IP03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1161099:CAPP RS08610
gene id: 1161099:CAPP_RS08610
uniprot id: A0A1N7JKF6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1161099:CAPP RS02185
gene id: 1161099:CAPP_RS02185
uniprot id: A0A1N7JBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1161099:CAPP RS05455
gene id: 1161099:CAPP_RS05455
uniprot id: A0A1N7IV76
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS02930
gene id: 1161099:CAPP_RS02930
uniprot id: A0A1N7KBA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1161099:CAPP RS06005
gene id: 1161099:CAPP_RS06005
uniprot id: A0A1N7IXD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1161099:CAPP RS01385
gene id: 1161099:CAPP_RS01385
uniprot id: A0A1N7IM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1161099:CAPP RS00310
gene id: 1161099:CAPP_RS00310
uniprot id: A0A1N7IPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS05985
gene id: 1161099:CAPP_RS05985
uniprot id: A0A1N7IXA8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1161099:CAPP RS08325
gene id: 1161099:CAPP_RS08325
uniprot id: A0A1N7JM80
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1161099:CAPP RS00220
gene id: 1161099:CAPP_RS00220
uniprot id: A0A1N7IPY4
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS07620
gene id: 1161099:CAPP_RS07620
uniprot id: A0A1N7J1G4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS09095
gene id: 1161099:CAPP_RS09095
uniprot id: A0A1N7K8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1161099:CAPP RS00010
gene id: 1161099:CAPP_RS00010
uniprot id: A0A1N7IQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1161099:CAPP RS00320
gene id: 1161099:CAPP_RS00320
uniprot id: A0A1N7IPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1161099:CAPP RS00860
gene id: 1161099:CAPP_RS00860
uniprot id: A0A1N7INI4
names: Subcellular Location Annotation
messages: Cytoplasm

1161099:CAPP RS10615
gene id: 1161099:CAPP_RS10615
uniprot id: A0A1N7JHN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1161099:CAPP RS11045
gene id: 1161099:CAPP_RS11045
uniprot id: A0A1N7IQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1161099:CAPP RS01755
gene id: 1161099:CAPP_RS01755
uniprot id: A0A1N7JAH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1161099:CAPP RS10915
gene id: 1161099:CAPP_RS10915
uniprot id: A0A1N7IQY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1161099:CAPP RS07795
gene id: 1161099:CAPP_RS07795
uniprot id: A0A1N7J0S7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1161099:CAPP RS09260
gene id: 1161099:CAPP_RS09260
uniprot id: A0A1N7K7A3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1161099:CAPP RS08580
gene id: 1161099:CAPP_RS08580
uniprot id: A0A1N7JKS6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1161099:CAPP RS08770
gene id: 1161099:CAPP_RS08770
uniprot id: A0A1N7JRN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1161099:CAPP RS07790
gene id: 1161099:CAPP_RS07790
uniprot id: A0A1N7J128
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1161099:CAPP RS08045
gene id: 1161099:CAPP_RS08045
uniprot id: A0A1N7J003
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1161099:CAPP RS00015
gene id: 1161099:CAPP_RS00015
uniprot id: A0A1N7IQD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1161099:CAPP RS10815
gene id: 1161099:CAPP_RS10815
uniprot id: A0A1N7IRC3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1161099:CAPP RS01760
gene id: 1161099:CAPP_RS01760
uniprot id: A0A1N7JAJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1161099:CAPP RS06745
gene id: 1161099:CAPP_RS06745
uniprot id: A0A1N7KHB3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1161099:CAPP RS03655
gene id: 1161099:CAPP_RS03655
uniprot id: A0A1N7JEB2
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS06685
gene id: 1161099:CAPP_RS06685
uniprot id: A0A1N7JFT4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS02470
gene id: 1161099:CAPP_RS02470
uniprot id: A0A1N7K183
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1161099:CAPP RS10255
gene id: 1161099:CAPP_RS10255
uniprot id: A0A1N7J8D6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1161099:CAPP RS04320
gene id: 1161099:CAPP_RS04320
uniprot id: A0A1N7K478
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1161099:CAPP RS05395
gene id: 1161099:CAPP_RS05395
uniprot id: A0A1N7IV93
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1161099:CAPP RS06270
gene id: 1161099:CAPP_RS06270
uniprot id: A0A1N7JGM0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1161099:CAPP RS07650
gene id: 1161099:CAPP_RS07650
uniprot id: A0A1N7J147
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1161099:CAPP RS01605
gene id: 1161099:CAPP_RS01605
uniprot id: A0A1N7J9T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1161099:CAPP RS07425
gene id: 1161099:CAPP_RS07425
uniprot id: A0A1N7J1X9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1161099:CAPP RS10560
gene id: 1161099:CAPP_RS10560
uniprot id: A0A1N7JHV2
names: Similarity
messages: Belongs to the FGGY kinase family.

1161099:CAPP RS09885
gene id: 1161099:CAPP_RS09885
uniprot id: A0A1N7J784
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1161099:CAPP RS01770
gene id: 1161099:CAPP_RS01770
uniprot id: A0A1N7JAL5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1161099:CAPP RS06890
gene id: 1161099:CAPP_RS06890
uniprot id: A0A1N7J3K1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1161099:CAPP RS02265
gene id: 1161099:CAPP_RS02265
uniprot id: A0A1N7JC47
names: Similarity
messages: Belongs to the AccD/PCCB family.

1161099:CAPP RS02405
gene id: 1161099:CAPP_RS02405
uniprot id: A0A1N7K0R3
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1161099:CAPP RS06260
gene id: 1161099:CAPP_RS06260
uniprot id: A0A1N7JGZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1161099:CAPP RS08890
gene id: 1161099:CAPP_RS08890
uniprot id: A0A1N7JQ97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1161099:CAPP RS05025
gene id: 1161099:CAPP_RS05025
uniprot id: A0A1N7ITZ2
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS08030
gene id: 1161099:CAPP_RS08030
uniprot id: A0A1N7IZY6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1161099:CAPP RS07270
gene id: 1161099:CAPP_RS07270
uniprot id: A0A1N7J2P3
names: Similarity
messages: Belongs to the YoeB family.

1161099:CAPP RS01610
gene id: 1161099:CAPP_RS01610
uniprot id: A0A1N7J9X3
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1161099:CAPP RS10490
gene id: 1161099:CAPP_RS10490
uniprot id: A0A1N7JHY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1161099:CAPP RS06360
gene id: 1161099:CAPP_RS06360
uniprot id: A0A1N7JGJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS06645
gene id: 1161099:CAPP_RS06645
uniprot id: A0A1N7JFR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1161099:CAPP RS09950
gene id: 1161099:CAPP_RS09950
uniprot id: A0A1N7J7J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1161099:CAPP RS09870
gene id: 1161099:CAPP_RS09870
uniprot id: A0A1N7J769
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1161099:CAPP RS01525
gene id: 1161099:CAPP_RS01525
uniprot id: A0A1N7J9J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1161099:CAPP RS00045
gene id: 1161099:CAPP_RS00045
uniprot id: A0A1N7IQL3
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).

1161099:CAPP RS01675
gene id: 1161099:CAPP_RS01675
uniprot id: A0A1N7JA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS08865
gene id: 1161099:CAPP_RS08865
uniprot id: A0A1N7JQG6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1161099:CAPP RS00800
gene id: 1161099:CAPP_RS00800
uniprot id: A0A1N7INS9
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS05710
gene id: 1161099:CAPP_RS05710
uniprot id: A0A1N7IW66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1161099:CAPP RS07375
gene id: 1161099:CAPP_RS07375
uniprot id: A0A1N7J207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1161099:CAPP RS04420
gene id: 1161099:CAPP_RS04420
uniprot id: A0A1N7K519
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1161099:CAPP RS05335
gene id: 1161099:CAPP_RS05335
uniprot id: A0A1N7IUT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS08420
gene id: 1161099:CAPP_RS08420
uniprot id: A0A1N7JLF2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1161099:CAPP RS08455
gene id: 1161099:CAPP_RS08455
uniprot id: A0A1N7JLI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1161099:CAPP RS09680
gene id: 1161099:CAPP_RS09680
uniprot id: A0A1N7J6P7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1161099:CAPP RS08670
gene id: 1161099:CAPP_RS08670
uniprot id: A0A1N7JK48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1161099:CAPP RS06075
gene id: 1161099:CAPP_RS06075
uniprot id: A0A1N7IX88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS02155
gene id: 1161099:CAPP_RS02155
uniprot id: A0A1N7JBS0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1161099:CAPP RS08765
gene id: 1161099:CAPP_RS08765
uniprot id: A0A1N7JRQ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1161099:CAPP RS07990
gene id: 1161099:CAPP_RS07990
uniprot id: A0A1N7J058
names: Similarity
messages: Belongs to the asparagine synthetase family.

1161099:CAPP RS10985
gene id: 1161099:CAPP_RS10985
uniprot id: A0A1N7IQQ3
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

1161099:CAPP RS07505
gene id: 1161099:CAPP_RS07505
uniprot id: A0A1N7J1L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1161099:CAPP RS08375
gene id: 1161099:CAPP_RS08375
uniprot id: A0A1N7JLR0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1161099:CAPP RS02880
gene id: 1161099:CAPP_RS02880
uniprot id: A0A1N7KAM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1161099:CAPP RS10770
gene id: 1161099:CAPP_RS10770
uniprot id: A0A1N7IR73
names: Similarity
messages: Belongs to the thioredoxin family.

1161099:CAPP RS01250
gene id: 1161099:CAPP_RS01250
uniprot id: A0A1N7IMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS00535
gene id: 1161099:CAPP_RS00535
uniprot id: A0A1N7IPB4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS07110
gene id: 1161099:CAPP_RS07110
uniprot id: A0A1N7J2Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1161099:CAPP RS10400
gene id: 1161099:CAPP_RS10400
uniprot id: A0A1N7JIH2
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS04475
gene id: 1161099:CAPP_RS04475
uniprot id: A0A1N7K5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1161099:CAPP RS01400
gene id: 1161099:CAPP_RS01400
uniprot id: A0A1N7IM24
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS08650
gene id: 1161099:CAPP_RS08650
uniprot id: A0A1N7JKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1161099:CAPP RS04465
gene id: 1161099:CAPP_RS04465
uniprot id: A0A1N7K5B0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1161099:CAPP RS05925
gene id: 1161099:CAPP_RS05925
uniprot id: A0A1N7IWZ1
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1161099:CAPP RS06255
gene id: 1161099:CAPP_RS06255
uniprot id: A0A1N7JH23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1161099:CAPP RS01545
gene id: 1161099:CAPP_RS01545
uniprot id: A0A1N7J9M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1161099:CAPP RS03395
gene id: 1161099:CAPP_RS03395
uniprot id: A0A1N7JDC5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1161099:CAPP RS02460
gene id: 1161099:CAPP_RS02460
uniprot id: A0A1N7K177
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1161099:CAPP RS01935
gene id: 1161099:CAPP_RS01935
uniprot id: A0A1N7JAY8
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1161099:CAPP RS01135
gene id: 1161099:CAPP_RS01135
uniprot id: A0A1N7IMZ9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1161099:CAPP RS06230
gene id: 1161099:CAPP_RS06230
uniprot id: A0A1N7IXQ4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1161099:CAPP RS09190
gene id: 1161099:CAPP_RS09190
uniprot id: A0A1N7K7Q4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1161099:CAPP RS05180
gene id: 1161099:CAPP_RS05180
uniprot id: A0A1N7IUG9
names: Similarity
messages: Belongs to the isochorismate synthase family.

1161099:CAPP RS06395
gene id: 1161099:CAPP_RS06395
uniprot id: A0A1N7JGM9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS04515
gene id: 1161099:CAPP_RS04515
uniprot id: A0A1N7KBU2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1161099:CAPP RS09960
gene id: 1161099:CAPP_RS09960
uniprot id: A0A1N7J7E8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1161099:CAPP RS05280
gene id: 1161099:CAPP_RS05280
uniprot id: A0A1N7IUV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1161099:CAPP RS00680
gene id: 1161099:CAPP_RS00680
uniprot id: A0A1N7IP05
names: Similarity
messages: Belongs to the catalase family.

1161099:CAPP RS00815
gene id: 1161099:CAPP_RS00815
uniprot id: A0A1N7INN4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1161099:CAPP RS02140
gene id: 1161099:CAPP_RS02140
uniprot id: A0A1N7JBS6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1161099:CAPP RS06580
gene id: 1161099:CAPP_RS06580
uniprot id: A0A1N7JFZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS01510
gene id: 1161099:CAPP_RS01510
uniprot id: A0A1N7J9K1
names: Similarity
messages: Belongs to the asp23 family.

1161099:CAPP RS02325
gene id: 1161099:CAPP_RS02325
uniprot id: A0A1N7KFK8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1161099:CAPP RS04035
gene id: 1161099:CAPP_RS04035
uniprot id: A0A1N7JU08
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1161099:CAPP RS07475
gene id: 1161099:CAPP_RS07475
uniprot id: A0A1N7J1M9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1161099:CAPP RS00005
gene id: 1161099:CAPP_RS00005
uniprot id: A0A1N7IQN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1161099:CAPP RS09655
gene id: 1161099:CAPP_RS09655
uniprot id: A0A1N7J6F6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1161099:CAPP RS01820
gene id: 1161099:CAPP_RS01820
uniprot id: A0A1N7JAU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1161099:CAPP RS00465
gene id: 1161099:CAPP_RS00465
uniprot id: A0A1N7IPF0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1161099:CAPP RS00695
gene id: 1161099:CAPP_RS00695
uniprot id: A0A1N7IP01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS07080
gene id: 1161099:CAPP_RS07080
uniprot id: A0A1N7J335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1161099:CAPP RS02090
gene id: 1161099:CAPP_RS02090
uniprot id: A0A1N7JBJ8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1161099:CAPP RS07405
gene id: 1161099:CAPP_RS07405
uniprot id: A0A1N7J289
names: Similarity
messages: Belongs to the UPF0102 family.

1161099:CAPP RS07705
gene id: 1161099:CAPP_RS07705
uniprot id: A0A1N7J151
names: Similarity
messages: Belongs to the IMPACT family.

1161099:CAPP RS06825
gene id: 1161099:CAPP_RS06825
uniprot id: A0A1N7J3T4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1161099:CAPP RS00370
gene id: 1161099:CAPP_RS00370
uniprot id: A0A1N7IPM1
names: Similarity
messages: Belongs to the peptidase M13 family.

1161099:CAPP RS08470
gene id: 1161099:CAPP_RS08470
uniprot id: A0A1N7JLF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1161099:CAPP RS10640
gene id: 1161099:CAPP_RS10640
uniprot id: A0A1N7JHP4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1161099:CAPP RS00345
gene id: 1161099:CAPP_RS00345
uniprot id: A0A1N7IPP4
names: Similarity
messages: Belongs to the UPF0145 family.

1161099:CAPP RS02085
gene id: 1161099:CAPP_RS02085
uniprot id: A0A1N7JBC9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1161099:CAPP RS03930
gene id: 1161099:CAPP_RS03930
uniprot id: A0A1N7JUT4
names: Similarity
messages: Belongs to the FBPase class 2 family.

1161099:CAPP RS00625
gene id: 1161099:CAPP_RS00625
uniprot id: A0A1N7IP59
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1161099:CAPP RS11130
gene id: 1161099:CAPP_RS11130
uniprot id: A0A1N7IQN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1161099:CAPP RS03925
gene id: 1161099:CAPP_RS03925
uniprot id: A0A1N7JV75
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1161099:CAPP RS06330
gene id: 1161099:CAPP_RS06330
uniprot id: A0A1N7JGR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1161099:CAPP RS08040
gene id: 1161099:CAPP_RS08040
uniprot id: A0A1N7J075
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1161099:CAPP RS01370
gene id: 1161099:CAPP_RS01370
uniprot id: A0A1N7IM62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1161099:CAPP RS01550
gene id: 1161099:CAPP_RS01550
uniprot id: A0A1N7J9Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1161099:CAPP RS03735
gene id: 1161099:CAPP_RS03735
uniprot id: A0A1N7JED0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1161099:CAPP RS10885
gene id: 1161099:CAPP_RS10885
uniprot id: A0A1N7IQX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1161099:CAPP RS04020
gene id: 1161099:CAPP_RS04020
uniprot id: A0A1N7JUC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1161099:CAPP RS01110
gene id: 1161099:CAPP_RS01110
uniprot id: A0A1N7IN07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1161099:CAPP RS01555
gene id: 1161099:CAPP_RS01555
uniprot id: A0A1N7J9M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1161099:CAPP RS04395
gene id: 1161099:CAPP_RS04395
uniprot id: A0A1N7K4P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1161099:CAPP RS07860
gene id: 1161099:CAPP_RS07860
uniprot id: A0A1N7J0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1161099:CAPP RS08570
gene id: 1161099:CAPP_RS08570
uniprot id: A0A1N7JKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1161099:CAPP RS04825
gene id: 1161099:CAPP_RS04825
uniprot id: A0A1N7ITB7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1161099:CAPP RS09665
gene id: 1161099:CAPP_RS09665
uniprot id: A0A1N7J6H2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1161099:CAPP RS07865
gene id: 1161099:CAPP_RS07865
uniprot id: A0A1N7J0U6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS08200
gene id: 1161099:CAPP_RS08200
uniprot id: A0A1N7IZQ7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1161099:CAPP RS05880
gene id: 1161099:CAPP_RS05880
uniprot id: A0A1N7IWZ9
names: Similarity
messages: Belongs to the peptidase M24B family.

1161099:CAPP RS05980
gene id: 1161099:CAPP_RS05980
uniprot id: A0A1N7IX06
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1161099:CAPP RS08630
gene id: 1161099:CAPP_RS08630
uniprot id: A0A1N7JKB1
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS03090
gene id: 1161099:CAPP_RS03090
uniprot id: A0A1N7JYI9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1161099:CAPP RS07090
gene id: 1161099:CAPP_RS07090
uniprot id: A0A1N7J2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1161099:CAPP RS01635
gene id: 1161099:CAPP_RS01635
uniprot id: A0A1N7J9X5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1161099:CAPP RS06640
gene id: 1161099:CAPP_RS06640
uniprot id: A0A1N7JFX6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1161099:CAPP RS04860
gene id: 1161099:CAPP_RS04860
uniprot id: A0A1N7ITE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1161099:CAPP RS00065
gene id: 1161099:CAPP_RS00065
uniprot id: A0A1N7IQA5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1161099:CAPP RS08550
gene id: 1161099:CAPP_RS08550
uniprot id: A0A1N7JKY7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1161099:CAPP RS09110
gene id: 1161099:CAPP_RS09110
uniprot id: A0A1N7K8C8
names: Similarity
messages: Belongs to the CsoR family.

1161099:CAPP RS06195
gene id: 1161099:CAPP_RS06195
uniprot id: A0A1N7IXL5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1161099:CAPP RS06055
gene id: 1161099:CAPP_RS06055
uniprot id: A0A1N7IXH7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1161099:CAPP RS01830
gene id: 1161099:CAPP_RS01830
uniprot id: A0A1N7JAT9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1161099:CAPP RS01720
gene id: 1161099:CAPP_RS01720
uniprot id: A0A1N7JAE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1161099:CAPP RS10385
gene id: 1161099:CAPP_RS10385
uniprot id: A0A1N7JIJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1161099:CAPP RS05805
gene id: 1161099:CAPP_RS05805
uniprot id: A0A1N7IWR8
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS07695
gene id: 1161099:CAPP_RS07695
uniprot id: A0A1N7J0Z3
names: Similarity
messages: Belongs to the HSP15 family.

1161099:CAPP RS03975
gene id: 1161099:CAPP_RS03975
uniprot id: A0A1N7JUQ2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1161099:CAPP RS03870
gene id: 1161099:CAPP_RS03870
uniprot id: A0A1N7JVH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1161099:CAPP RS07445
gene id: 1161099:CAPP_RS07445
uniprot id: A0A1N7J247
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1161099:CAPP RS07255
gene id: 1161099:CAPP_RS07255
uniprot id: A0A1N7J2T2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-66 and Arg-69) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1161099:CAPP RS00615
gene id: 1161099:CAPP_RS00615
uniprot id: A0A1N7IP58
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1161099:CAPP RS01275
gene id: 1161099:CAPP_RS01275
uniprot id: A0A1N7IME1
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1161099:CAPP RS03110
gene id: 1161099:CAPP_RS03110
uniprot id: A0A1N7JYD3
names: Similarity
messages: Belongs to the citrate synthase family.

1161099:CAPP RS05635
gene id: 1161099:CAPP_RS05635
uniprot id: A0A1N7IVW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS06635
gene id: 1161099:CAPP_RS06635
uniprot id: A0A1N7JFL3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1161099:CAPP RS06465
gene id: 1161099:CAPP_RS06465
uniprot id: A0A1N7JGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1161099:CAPP RS09430
gene id: 1161099:CAPP_RS09430
uniprot id: A0A1N7J5Q8
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS10095
gene id: 1161099:CAPP_RS10095
uniprot id: A0A1N7J849
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS01230
gene id: 1161099:CAPP_RS01230
uniprot id: A0A1N7IMF3
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS06400
gene id: 1161099:CAPP_RS06400
uniprot id: A0A1N7JGF2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1161099:CAPP RS08980
gene id: 1161099:CAPP_RS08980
uniprot id: A0A1N7JPY1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1161099:CAPP RS09350
gene id: 1161099:CAPP_RS09350
uniprot id: A0A1N7KGW1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1161099:CAPP RS08065
gene id: 1161099:CAPP_RS08065
uniprot id: A0A1N7J019
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

1161099:CAPP RS01175
gene id: 1161099:CAPP_RS01175
uniprot id: A0A1N7IMM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1161099:CAPP RS06215
gene id: 1161099:CAPP_RS06215
uniprot id: A0A1N7IXP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1161099:CAPP RS00180
gene id: 1161099:CAPP_RS00180
uniprot id: A0A1N7IQ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1161099:CAPP RS06630
gene id: 1161099:CAPP_RS06630
uniprot id: A0A1N7JFZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1161099:CAPP RS05960
gene id: 1161099:CAPP_RS05960
uniprot id: A0A1N7IX28
names: Similarity
messages: Belongs to the peptidase M18 family.

1161099:CAPP RS06295
gene id: 1161099:CAPP_RS06295
uniprot id: A0A1N7JGL2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1161099:CAPP RS06995
gene id: 1161099:CAPP_RS06995
uniprot id: A0A1N7J373
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1161099:CAPP RS04480
gene id: 1161099:CAPP_RS04480
uniprot id: A0A1N7K5L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1161099:CAPP RS10880
gene id: 1161099:CAPP_RS10880
uniprot id: A0A1N7IQW5
names: Cofactor
messages: Can also use Mn(2+) ion.

1161099:CAPP RS10955
gene id: 1161099:CAPP_RS10955
uniprot id: A0A1N7IQT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS05435
gene id: 1161099:CAPP_RS05435
uniprot id: A0A1N7IV68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1161099:CAPP RS08760
gene id: 1161099:CAPP_RS08760
uniprot id: A0A1N7JRQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1161099:CAPP RS10190
gene id: 1161099:CAPP_RS10190
uniprot id: A0A1N7J899
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1161099:CAPP RS00835
gene id: 1161099:CAPP_RS00835
uniprot id: A0A1N7INX5
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS03435
gene id: 1161099:CAPP_RS03435
uniprot id: A0A1N7JDL4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1161099:CAPP RS05640
gene id: 1161099:CAPP_RS05640
uniprot id: A0A1N7IW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1161099:CAPP RS06285
gene id: 1161099:CAPP_RS06285
uniprot id: A0A1N7JGM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1161099:CAPP RS10415
gene id: 1161099:CAPP_RS10415
uniprot id: A0A1N7JIA0
names: Similarity
messages: Belongs to the CFA/CMAS family.

1161099:CAPP RS07285
gene id: 1161099:CAPP_RS07285
uniprot id: A0A1N7J2M3
names: Similarity
messages: Belongs to the MQO family.

1161099:CAPP RS04380
gene id: 1161099:CAPP_RS04380
uniprot id: A0A1N7K4Q6
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1161099:CAPP RS11005
gene id: 1161099:CAPP_RS11005
uniprot id: A0A1N7IQN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1161099:CAPP RS01345
gene id: 1161099:CAPP_RS01345
uniprot id: A0A1N7IM68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1161099:CAPP RS07320
gene id: 1161099:CAPP_RS07320
uniprot id: A0A1N7J270
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1161099:CAPP RS10320
gene id: 1161099:CAPP_RS10320
uniprot id: A0A1N7JIK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1161099:CAPP RS05250
gene id: 1161099:CAPP_RS05250
uniprot id: A0A1N7IUK6
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS05920
gene id: 1161099:CAPP_RS05920
uniprot id: A0A1N7IWW9
names: Similarity
messages: Belongs to the prokaryotic ubiquitin-like protein family.

1161099:CAPP RS02620
gene id: 1161099:CAPP_RS02620
uniprot id: A0A1N7K2C1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1161099:CAPP RS09805
gene id: 1161099:CAPP_RS09805
uniprot id: A0A1N7J6Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1161099:CAPP RS03225
gene id: 1161099:CAPP_RS03225
uniprot id: A0A1N7JXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1161099:CAPP RS03355
gene id: 1161099:CAPP_RS03355
uniprot id: A0A1N7JD78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1161099:CAPP RS06355
gene id: 1161099:CAPP_RS06355
uniprot id: A0A1N7JGD3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS05295
gene id: 1161099:CAPP_RS05295
uniprot id: A0A1N7IUR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1161099:CAPP RS00190
gene id: 1161099:CAPP_RS00190
uniprot id: A0A1N7IQ24
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS06420
gene id: 1161099:CAPP_RS06420
uniprot id: A0A1N7JGI6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1161099:CAPP RS03620
gene id: 1161099:CAPP_RS03620
uniprot id: A0A1N7JEC8
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1161099:CAPP RS08355
gene id: 1161099:CAPP_RS08355
uniprot id: A0A1N7JM67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1161099:CAPP RS09235
gene id: 1161099:CAPP_RS09235
uniprot id: A0A1N7K7D0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1161099:CAPP RS04845
gene id: 1161099:CAPP_RS04845
uniprot id: A0A1N7ITD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1161099:CAPP RS05770
gene id: 1161099:CAPP_RS05770
uniprot id: A0A1N7IWD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1161099:CAPP RS08405
gene id: 1161099:CAPP_RS08405
uniprot id: A0A1N7JLQ3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1161099:CAPP RS10765
gene id: 1161099:CAPP_RS10765
uniprot id: A0A1N7IR88
names: Similarity
messages: Belongs to the PspA/IM30 family.

1161099:CAPP RS04945
gene id: 1161099:CAPP_RS04945
uniprot id: A0A1N7IU19
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1161099:CAPP RS04905
gene id: 1161099:CAPP_RS04905
uniprot id: A0A1N7ITJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1161099:CAPP RS00170
gene id: 1161099:CAPP_RS00170
uniprot id: A0A1N7IQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1161099:CAPP RS06530
gene id: 1161099:CAPP_RS06530
uniprot id: A0A1N7JFY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS10130
gene id: 1161099:CAPP_RS10130
uniprot id: A0A1N7J8B2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1161099:CAPP RS09410
gene id: 1161099:CAPP_RS09410
uniprot id: A0A1N7J5F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1161099:CAPP RS07550
gene id: 1161099:CAPP_RS07550
uniprot id: A0A1N7J1E5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1161099:CAPP RS07970
gene id: 1161099:CAPP_RS07970
uniprot id: A0A1N7J0L6
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1161099:CAPP RS07810
gene id: 1161099:CAPP_RS07810
uniprot id: A0A1N7J0N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1161099:CAPP RS01900
gene id: 1161099:CAPP_RS01900
uniprot id: A0A1N7JAU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1161099:CAPP RS01440
gene id: 1161099:CAPP_RS01440
uniprot id: A0A1N7ILY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1161099:CAPP RS09790
gene id: 1161099:CAPP_RS09790
uniprot id: A0A1N7J6R7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1161099:CAPP RS05630
gene id: 1161099:CAPP_RS05630
uniprot id: A0A1N7IVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1161099:CAPP RS11050
gene id: 1161099:CAPP_RS11050
uniprot id: A0A1N7IQK1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1161099:CAPP RS07430
gene id: 1161099:CAPP_RS07430
uniprot id: A0A1N7J1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1161099:CAPP RS00540
gene id: 1161099:CAPP_RS00540
uniprot id: A0A1N7IPC0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1161099:CAPP RS02870
gene id: 1161099:CAPP_RS02870
uniprot id: A0A1N7KAJ3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1161099:CAPP RS04240
gene id: 1161099:CAPP_RS04240
uniprot id: A0A1N7KEA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1161099:CAPP RS02605
gene id: 1161099:CAPP_RS02605
uniprot id: A0A1N7K280
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1161099:CAPP RS10820
gene id: 1161099:CAPP_RS10820
uniprot id: A0A1N7IR28
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS05585
gene id: 1161099:CAPP_RS05585
uniprot id: A0A1N7IVQ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1161099:CAPP RS04455
gene id: 1161099:CAPP_RS04455
uniprot id: A0A1N7K5E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1161099:CAPP RS06610
gene id: 1161099:CAPP_RS06610
uniprot id: A0A1N7JFU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS10175
gene id: 1161099:CAPP_RS10175
uniprot id: A0A1N7J839
names: Similarity
messages: Belongs to the TPP enzyme family.

1161099:CAPP RS02755
gene id: 1161099:CAPP_RS02755
uniprot id: A0A1N7K9N1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1161099:CAPP RS06380
gene id: 1161099:CAPP_RS06380
uniprot id: A0A1N7JGG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1161099:CAPP RS05735
gene id: 1161099:CAPP_RS05735
uniprot id: A0A1N7IWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1161099:CAPP RS09755
gene id: 1161099:CAPP_RS09755
uniprot id: A0A1N7J6Y7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS08855
gene id: 1161099:CAPP_RS08855
uniprot id: A0A1N7JQW6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1161099:CAPP RS04670
gene id: 1161099:CAPP_RS04670
uniprot id: A0A1N7KD34
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS03600
gene id: 1161099:CAPP_RS03600
uniprot id: A0A1N7JE77
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1161099:CAPP RS08800
gene id: 1161099:CAPP_RS08800
uniprot id: A0A1N7JR43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1161099:CAPP RS09925
gene id: 1161099:CAPP_RS09925
uniprot id: A0A1N7J7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS02555
gene id: 1161099:CAPP_RS02555
uniprot id: A0A1N7K2C4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1161099:CAPP RS01360
gene id: 1161099:CAPP_RS01360
uniprot id: A0A1N7IMD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1161099:CAPP RS05320
gene id: 1161099:CAPP_RS05320
uniprot id: A0A1N7IUT6
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1161099:CAPP RS03920
gene id: 1161099:CAPP_RS03920
uniprot id: A0A1N7JUY0
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS04870
gene id: 1161099:CAPP_RS04870
uniprot id: A0A1N7ITT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1161099:CAPP RS09810
gene id: 1161099:CAPP_RS09810
uniprot id: A0A1N7J6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1161099:CAPP RS01140
gene id: 1161099:CAPP_RS01140
uniprot id: A0A1N7IMX8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1161099:CAPP RS03505
gene id: 1161099:CAPP_RS03505
uniprot id: A0A1N7JDX4
names: Similarity
messages: Belongs to the TPP enzyme family.

1161099:CAPP RS03145
gene id: 1161099:CAPP_RS03145
uniprot id: A0A1N7JY42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1161099:CAPP RS07295
gene id: 1161099:CAPP_RS07295
uniprot id: A0A1N7J2K8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1161099:CAPP RS06835
gene id: 1161099:CAPP_RS06835
uniprot id: A0A1N7J432
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1161099:CAPP RS01930
gene id: 1161099:CAPP_RS01930
uniprot id: A0A1N7JAV5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1161099:CAPP RS06390
gene id: 1161099:CAPP_RS06390
uniprot id: A0A1N7JG98
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1161099:CAPP RS01710
gene id: 1161099:CAPP_RS01710
uniprot id: A0A1N7JA51
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1161099:CAPP RS09565
gene id: 1161099:CAPP_RS09565
uniprot id: A0A1N7J654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS05460
gene id: 1161099:CAPP_RS05460
uniprot id: A0A1N7IVJ4
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS02855
gene id: 1161099:CAPP_RS02855
uniprot id: A0A1N7KAF5
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1161099:CAPP RS10195
gene id: 1161099:CAPP_RS10195
uniprot id: A0A1N7J860
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1161099:CAPP RS08930
gene id: 1161099:CAPP_RS08930
uniprot id: A0A1N7JQ18
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1161099:CAPP RS05940
gene id: 1161099:CAPP_RS05940
uniprot id: A0A1N7IWY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1161099:CAPP RS08060
gene id: 1161099:CAPP_RS08060
uniprot id: A0A1N7J091
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1161099:CAPP RS05580
gene id: 1161099:CAPP_RS05580
uniprot id: A0A1N7IVW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1161099:CAPP RS03270
gene id: 1161099:CAPP_RS03270
uniprot id: A0A1N7JX48
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS03780
gene id: 1161099:CAPP_RS03780
uniprot id: A0A1N7JEN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1161099:CAPP RS01520
gene id: 1161099:CAPP_RS01520
uniprot id: A0A1N7J9L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1161099:CAPP RS09040
gene id: 1161099:CAPP_RS09040
uniprot id: A0A1N7JPF1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1161099:CAPP RS02225
gene id: 1161099:CAPP_RS02225
uniprot id: A0A1N7JBV4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1161099:CAPP RS03205
gene id: 1161099:CAPP_RS03205
uniprot id: A0A1N7JXI8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1161099:CAPP RS08160
gene id: 1161099:CAPP_RS08160
uniprot id: A0A1N7IZI2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1161099:CAPP RS06920
gene id: 1161099:CAPP_RS06920
uniprot id: A0A1N7J3V8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1161099:CAPP RS00480
gene id: 1161099:CAPP_RS00480
uniprot id: A0A1N7IPF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1161099:CAPP RS00590
gene id: 1161099:CAPP_RS00590
uniprot id: A0A1N7IP84
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1161099:CAPP RS08395
gene id: 1161099:CAPP_RS08395
uniprot id: A0A1N7JLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS05530
gene id: 1161099:CAPP_RS05530
uniprot id: A0A1N7IVH4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1161099:CAPP RS06930
gene id: 1161099:CAPP_RS06930
uniprot id: A0A1N7J3K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1161099:CAPP RS07855
gene id: 1161099:CAPP_RS07855
uniprot id: A0A1N7J0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS08820
gene id: 1161099:CAPP_RS08820
uniprot id: A0A1N7JQY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1161099:CAPP RS07065
gene id: 1161099:CAPP_RS07065
uniprot id: A0A1N7J2Y5
names: Similarity
messages: Belongs to the PspA/IM30 family.

1161099:CAPP RS00635
gene id: 1161099:CAPP_RS00635
uniprot id: A0A1N7IPE4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1161099:CAPP RS08590
gene id: 1161099:CAPP_RS08590
uniprot id: A0A1N7JKS1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1161099:CAPP RS06110
gene id: 1161099:CAPP_RS06110
uniprot id: A0A1N7IXD1
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1161099:CAPP RS09730
gene id: 1161099:CAPP_RS09730
uniprot id: A0A1N7J6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1161099:CAPP RS04155
gene id: 1161099:CAPP_RS04155
uniprot id: A0A1N7JSZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1161099:CAPP RS00650
gene id: 1161099:CAPP_RS00650
uniprot id: A0A1N7IP39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS03060
gene id: 1161099:CAPP_RS03060
uniprot id: A0A1N7JZ64
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1161099:CAPP RS09500
gene id: 1161099:CAPP_RS09500
uniprot id: A0A1N7J5S3
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1161099:CAPP RS01170
gene id: 1161099:CAPP_RS01170
uniprot id: A0A1N7IMV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS10535
gene id: 1161099:CAPP_RS10535
uniprot id: A0A1N7JHR2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1161099:CAPP RS01905
gene id: 1161099:CAPP_RS01905
uniprot id: A0A1N7JAY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1161099:CAPP RS07585
gene id: 1161099:CAPP_RS07585
uniprot id: A0A1N7J1M7
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1161099:CAPP RS04560
gene id: 1161099:CAPP_RS04560
uniprot id: A0A1N7KC65
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1161099:CAPP RS05310
gene id: 1161099:CAPP_RS05310
uniprot id: A0A1N7IUW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1161099:CAPP RS00675
gene id: 1161099:CAPP_RS00675
uniprot id: A0A1N7IP17
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1161099:CAPP RS02895
gene id: 1161099:CAPP_RS02895
uniprot id: A0A1N7KAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1161099:CAPP RS04015
gene id: 1161099:CAPP_RS04015
uniprot id: A0A1N7JU70
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS06265
gene id: 1161099:CAPP_RS06265
uniprot id: A0A1N7JGR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1161099:CAPP RS08815
gene id: 1161099:CAPP_RS08815
uniprot id: A0A1N7JR88
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1161099:CAPP RS00495
gene id: 1161099:CAPP_RS00495
uniprot id: A0A1N7IPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1161099:CAPP RS09270
gene id: 1161099:CAPP_RS09270
uniprot id: A0A1N7K743
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1161099:CAPP RS05075
gene id: 1161099:CAPP_RS05075
uniprot id: A0A1N7IUA1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1161099:CAPP RS06650
gene id: 1161099:CAPP_RS06650
uniprot id: A0A1N7JFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1161099:CAPP RS06695
gene id: 1161099:CAPP_RS06695
uniprot id: A0A1N7JFS4
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS02900
gene id: 1161099:CAPP_RS02900
uniprot id: A0A1N7KAU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1161099:CAPP RS00630
gene id: 1161099:CAPP_RS00630
uniprot id: A0A1N7IP48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1161099:CAPP RS02840
gene id: 1161099:CAPP_RS02840
uniprot id: A0A1N7KAH3
names: Similarity
messages: Belongs to the ectoine synthase family.

1161099:CAPP RS08210
gene id: 1161099:CAPP_RS08210
uniprot id: A0A1N7IZB1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1161099:CAPP RS06180
gene id: 1161099:CAPP_RS06180
uniprot id: A0A1N7IXU7
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS07930
gene id: 1161099:CAPP_RS07930
uniprot id: A0A1N7J0C3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

1161099:CAPP RS03465
gene id: 1161099:CAPP_RS03465
uniprot id: A0A1N7JDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1161099:CAPP RS09435
gene id: 1161099:CAPP_RS09435
uniprot id: A0A1N7J5K8
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS02105
gene id: 1161099:CAPP_RS02105
uniprot id: A0A1N7JBI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS01975
gene id: 1161099:CAPP_RS01975
uniprot id: A0A1N7JB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1161099:CAPP RS02515
gene id: 1161099:CAPP_RS02515
uniprot id: A0A1N7K1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1161099:CAPP RS03105
gene id: 1161099:CAPP_RS03105
uniprot id: A0A1N7JYT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS08465
gene id: 1161099:CAPP_RS08465
uniprot id: A0A1N7JL85
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1161099:CAPP RS06475
gene id: 1161099:CAPP_RS06475
uniprot id: A0A1N7JGE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1161099:CAPP RS09580
gene id: 1161099:CAPP_RS09580
uniprot id: A0A1N7J660
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1161099:CAPP RS03440
gene id: 1161099:CAPP_RS03440
uniprot id: A0A1N7JDK8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1161099:CAPP RS09965
gene id: 1161099:CAPP_RS09965
uniprot id: A0A1N7J7K0
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS07820
gene id: 1161099:CAPP_RS07820
uniprot id: A0A1N7J0Q6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1161099:CAPP RS07170
gene id: 1161099:CAPP_RS07170
uniprot id: A0A1N7J2S9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1161099:CAPP RS05680
gene id: 1161099:CAPP_RS05680
uniprot id: A0A1N7IWB9
names: Similarity
messages: Belongs to the TlyA family.

1161099:CAPP RS03415
gene id: 1161099:CAPP_RS03415
uniprot id: A0A1N7JDK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1161099:CAPP RS05275
gene id: 1161099:CAPP_RS05275
uniprot id: A0A1N7IUV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1161099:CAPP RS06885
gene id: 1161099:CAPP_RS06885
uniprot id: A0A1N7J3L2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1161099:CAPP RS09465
gene id: 1161099:CAPP_RS09465
uniprot id: A0A1N7J5N4
names: Similarity
messages: Belongs to the PhoU family.

1161099:CAPP RS04370
gene id: 1161099:CAPP_RS04370
uniprot id: A0A1N7K4G7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1161099:CAPP RS02805
gene id: 1161099:CAPP_RS02805
uniprot id: A0A1N7KA48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1161099:CAPP RS06410
gene id: 1161099:CAPP_RS06410
uniprot id: A0A1N7JG78
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1161099:CAPP RS04295
gene id: 1161099:CAPP_RS04295
uniprot id: A0A1N7K4A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1161099:CAPP RS02485
gene id: 1161099:CAPP_RS02485
uniprot id: A0A1N7K1H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1161099:CAPP RS09980
gene id: 1161099:CAPP_RS09980
uniprot id: A0A1N7J7L8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1161099:CAPP RS02220
gene id: 1161099:CAPP_RS02220
uniprot id: A0A1N7JC12
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1161099:CAPP RS04880
gene id: 1161099:CAPP_RS04880
uniprot id: A0A1N7ITU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1161099:CAPP RS07200
gene id: 1161099:CAPP_RS07200
uniprot id: A0A1N7J2H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1161099:CAPP RS01290
gene id: 1161099:CAPP_RS01290
uniprot id: A0A1N7IM89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1161099:CAPP RS01775
gene id: 1161099:CAPP_RS01775
uniprot id: A0A1N7JAD6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1161099:CAPP RS07965
gene id: 1161099:CAPP_RS07965
uniprot id: A0A1N7J0I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1161099:CAPP RS08545
gene id: 1161099:CAPP_RS08545
uniprot id: A0A1N7JKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

1161099:CAPP RS00500
gene id: 1161099:CAPP_RS00500
uniprot id: A0A1N7IPE9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1161099:CAPP RS04715
gene id: 1161099:CAPP_RS04715
uniprot id: A0A1N7KII1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1161099:CAPP RS02175
gene id: 1161099:CAPP_RS02175
uniprot id: A0A1N7JBQ2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1161099:CAPP RS00155
gene id: 1161099:CAPP_RS00155
uniprot id: A0A1N7IQ49
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1161099:CAPP RS05490
gene id: 1161099:CAPP_RS05490
uniprot id: A0A1N7IVK2
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1161099:CAPP RS03055
gene id: 1161099:CAPP_RS03055
uniprot id: A0A1N7JYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cell inner membrane
messages: Membrane

1161099:CAPP RS02715
gene id: 1161099:CAPP_RS02715
uniprot id: A0A1N7KF19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1161099:CAPP RS07275
gene id: 1161099:CAPP_RS07275
uniprot id: A0A1N7J2H1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1161099:CAPP RS04850
gene id: 1161099:CAPP_RS04850
uniprot id: A0A1N7ITD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1161099:CAPP RS04835
gene id: 1161099:CAPP_RS04835
uniprot id: A0A1N7ITC8
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS07210
gene id: 1161099:CAPP_RS07210
uniprot id: A0A1N7J2H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1161099:CAPP RS05655
gene id: 1161099:CAPP_RS05655
uniprot id: A0A1N7IW89
names: Similarity
messages: Belongs to the UPF0434 family.

1161099:CAPP RS06605
gene id: 1161099:CAPP_RS06605
uniprot id: A0A1N7JFU0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1161099:CAPP RS03940
gene id: 1161099:CAPP_RS03940
uniprot id: A0A1N7JUT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1161099:CAPP RS02110
gene id: 1161099:CAPP_RS02110
uniprot id: A0A1N7JBL8
names: Subcellular Location Annotation
messages: Membrane

1161099:CAPP RS06045
gene id: 1161099:CAPP_RS06045
uniprot id: A0A1N7IXG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1161099:CAPP RS05055
gene id: 1161099:CAPP_RS05055
uniprot id: A0A1N7IU22
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1161099:CAPP RS05015
gene id: 1161099:CAPP_RS05015
uniprot id: A0A1N7ITY1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1161099:CAPP RS06145
gene id: 1161099:CAPP_RS06145
uniprot id: A0A1N7IXK5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1161099:CAPP RS01890
gene id: 1161099:CAPP_RS01890
uniprot id: A0A1N7JAZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1161099:CAPP RS08460
gene id: 1161099:CAPP_RS08460
uniprot id: A0A1N7JL69
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1161099:CAPP RS02520
gene id: 1161099:CAPP_RS02520
uniprot id: A0A1N7K1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1161099:CAPP RS03745
gene id: 1161099:CAPP_RS03745
uniprot id: A0A1N7JEG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1161099:CAPP RS07280
gene id: 1161099:CAPP_RS07280
uniprot id: A0A1N7J292
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).