1150469:RSPPHO RS00970
gene id: 1150469:RSPPHO_RS00970
uniprot id: H6SM94
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS12070
gene id: 1150469:RSPPHO_RS12070
uniprot id: H6SLL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1150469:RSPPHO RS14810
gene id: 1150469:RSPPHO_RS14810
uniprot id: H6SNR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1150469:RSPPHO RS06670
gene id: 1150469:RSPPHO_RS06670
uniprot id: H6SSI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1150469:RSPPHO RS00220
gene id: 1150469:RSPPHO_RS00220
uniprot id: H6SIK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1150469:RSPPHO RS00655
gene id: 1150469:RSPPHO_RS00655
uniprot id: H6SIT5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1150469:RSPPHO RS07865
gene id: 1150469:RSPPHO_RS07865
uniprot id: H6SJD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1150469:RSPPHO RS11510
gene id: 1150469:RSPPHO_RS11510
uniprot id: H6SLB3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1150469:RSPPHO RS10735
gene id: 1150469:RSPPHO_RS10735
uniprot id: H6SKX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1150469:RSPPHO RS04925
gene id: 1150469:RSPPHO_RS04925
uniprot id: H6SRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1150469:RSPPHO RS11340
gene id: 1150469:RSPPHO_RS11340
uniprot id: H6SL79
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1150469:RSPPHO RS12520
gene id: 1150469:RSPPHO_RS12520
uniprot id: H6SLU8
names: Similarity
messages: Belongs to the GSP E family.

1150469:RSPPHO RS14885
gene id: 1150469:RSPPHO_RS14885
uniprot id: H6SP86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1150469:RSPPHO RS05240
gene id: 1150469:RSPPHO_RS05240
uniprot id: H6SRQ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1150469:RSPPHO RS01575
gene id: 1150469:RSPPHO_RS01575
uniprot id: H6SN19
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1150469:RSPPHO RS00215
gene id: 1150469:RSPPHO_RS00215
uniprot id: H6SIK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1150469:RSPPHO RS14450
gene id: 1150469:RSPPHO_RS14450
uniprot id: H6SNJ4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1150469:RSPPHO RS09420
gene id: 1150469:RSPPHO_RS09420
uniprot id: H6SK63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS01320
gene id: 1150469:RSPPHO_RS01320
uniprot id: H6SMW9
names: Similarity
messages: Belongs to the aspartokinase family.

1150469:RSPPHO RS07175
gene id: 1150469:RSPPHO_RS07175
uniprot id: H6SIZ8
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS01045
gene id: 1150469:RSPPHO_RS01045
uniprot id: H6SMA9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1150469:RSPPHO RS10645
gene id: 1150469:RSPPHO_RS10645
uniprot id: H6SKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS10570
gene id: 1150469:RSPPHO_RS10570
uniprot id: H6SKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1150469:RSPPHO RS14560
gene id: 1150469:RSPPHO_RS14560
uniprot id: H6SNL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1150469:RSPPHO RS01150
gene id: 1150469:RSPPHO_RS01150
uniprot id: H6SMC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1150469:RSPPHO RS01330
gene id: 1150469:RSPPHO_RS01330
uniprot id: H6SMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1150469:RSPPHO RS03730
gene id: 1150469:RSPPHO_RS03730
uniprot id: H6SQ35
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1150469:RSPPHO RS01935
gene id: 1150469:RSPPHO_RS01935
uniprot id: H6SN91
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1150469:RSPPHO RS01135
gene id: 1150469:RSPPHO_RS01135
uniprot id: H6SMC5
names: Similarity
messages: Belongs to the PhoH family.

1150469:RSPPHO RS07920
gene id: 1150469:RSPPHO_RS07920
uniprot id: H6SJE4
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS01250
gene id: 1150469:RSPPHO_RS01250
uniprot id: H6SME7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1150469:RSPPHO RS10705
gene id: 1150469:RSPPHO_RS10705
uniprot id: H6SKW5
names: Similarity
messages: Belongs to the PrpD family.

1150469:RSPPHO RS13880
gene id: 1150469:RSPPHO_RS13880
uniprot id: H6SMS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1150469:RSPPHO RS05660
gene id: 1150469:RSPPHO_RS05660
uniprot id: H6SRY8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1150469:RSPPHO RS03015
gene id: 1150469:RSPPHO_RS03015
uniprot id: H6SPP3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1150469:RSPPHO RS08155
gene id: 1150469:RSPPHO_RS08155
uniprot id: H6SJI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1150469:RSPPHO RS06615
gene id: 1150469:RSPPHO_RS06615
uniprot id: H6SSH3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1150469:RSPPHO RS06795
gene id: 1150469:RSPPHO_RS06795
uniprot id: H6SSK9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1150469:RSPPHO RS07780
gene id: 1150469:RSPPHO_RS07780
uniprot id: H6SJB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1150469:RSPPHO RS05915
gene id: 1150469:RSPPHO_RS05915
uniprot id: H6SS38
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1150469:RSPPHO RS10510
gene id: 1150469:RSPPHO_RS10510
uniprot id: H6SKS4
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS07035
gene id: 1150469:RSPPHO_RS07035
uniprot id: H6SIX0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1150469:RSPPHO RS09555
gene id: 1150469:RSPPHO_RS09555
uniprot id: H6SK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1150469:RSPPHO RS05165
gene id: 1150469:RSPPHO_RS05165
uniprot id: H6SRP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1150469:RSPPHO RS13865
gene id: 1150469:RSPPHO_RS13865
uniprot id: H6SMS1
names: Similarity
messages: Belongs to the bacterial flagellin family.

1150469:RSPPHO RS00810
gene id: 1150469:RSPPHO_RS00810
uniprot id: H6SIH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1150469:RSPPHO RS01070
gene id: 1150469:RSPPHO_RS01070
uniprot id: H6SMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1150469:RSPPHO RS10715
gene id: 1150469:RSPPHO_RS10715
uniprot id: H6SKW7
names: Similarity
messages: Belongs to the citrate synthase family.

1150469:RSPPHO RS03035
gene id: 1150469:RSPPHO_RS03035
uniprot id: H6SPP8
names: Similarity
messages: Belongs to the TrpC family.

1150469:RSPPHO RS11725
gene id: 1150469:RSPPHO_RS11725
uniprot id: H6SLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1150469:RSPPHO RS10810
gene id: 1150469:RSPPHO_RS10810
uniprot id: H6SKY3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1150469:RSPPHO RS03670
gene id: 1150469:RSPPHO_RS03670
uniprot id: H6SQ23
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1150469:RSPPHO RS03180
gene id: 1150469:RSPPHO_RS03180
uniprot id: H6SPS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS04260
gene id: 1150469:RSPPHO_RS04260
uniprot id: H6SQT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Membrane

1150469:RSPPHO RS10075
gene id: 1150469:RSPPHO_RS10075
uniprot id: H6SKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1150469:RSPPHO RS06405
gene id: 1150469:RSPPHO_RS06405
uniprot id: H6SSD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1150469:RSPPHO RS06925
gene id: 1150469:RSPPHO_RS06925
uniprot id: H6SSN5
names: Similarity
messages: Belongs to the RecJ family.

1150469:RSPPHO RS01600
gene id: 1150469:RSPPHO_RS01600
uniprot id: H6SN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1150469:RSPPHO RS16355
gene id: 1150469:RSPPHO_RS16355
uniprot id: H6SQG5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1150469:RSPPHO RS14415
gene id: 1150469:RSPPHO_RS14415
uniprot id: H6SNI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1150469:RSPPHO RS04030
gene id: 1150469:RSPPHO_RS04030
uniprot id: H6SQP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1150469:RSPPHO RS15395
gene id: 1150469:RSPPHO_RS15395
uniprot id: H6SPI1
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1150469:RSPPHO RS11135
gene id: 1150469:RSPPHO_RS11135
uniprot id: H6SL41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.

1150469:RSPPHO RS05520
gene id: 1150469:RSPPHO_RS05520
uniprot id: H6SRW2
names: Similarity
messages: Belongs to the LOG family.

1150469:RSPPHO RS00685
gene id: 1150469:RSPPHO_RS00685
uniprot id: H6SIU2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1150469:RSPPHO RS06885
gene id: 1150469:RSPPHO_RS06885
uniprot id: H6SSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1150469:RSPPHO RS05430
gene id: 1150469:RSPPHO_RS05430
uniprot id: H6SRU6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1150469:RSPPHO RS07085
gene id: 1150469:RSPPHO_RS07085
uniprot id: H6SIY0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1150469:RSPPHO RS11700
gene id: 1150469:RSPPHO_RS11700
uniprot id: H6SLE8
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS05050
gene id: 1150469:RSPPHO_RS05050
uniprot id: H6SRM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1150469:RSPPHO RS06850
gene id: 1150469:RSPPHO_RS06850
uniprot id: H6SSM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1150469:RSPPHO RS07850
gene id: 1150469:RSPPHO_RS07850
uniprot id: H6SJD0
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1150469:RSPPHO RS03845
gene id: 1150469:RSPPHO_RS03845
uniprot id: H6SQL3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1150469:RSPPHO RS00990
gene id: 1150469:RSPPHO_RS00990
uniprot id: H6SM98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1150469:RSPPHO RS16580
gene id: 1150469:RSPPHO_RS16580
uniprot id: H6SQZ7
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS14480
gene id: 1150469:RSPPHO_RS14480
uniprot id: H6SNK0
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS06750
gene id: 1150469:RSPPHO_RS06750
uniprot id: H6SSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1150469:RSPPHO RS16225
gene id: 1150469:RSPPHO_RS16225
uniprot id: H6SQE1
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1150469:RSPPHO RS12935
gene id: 1150469:RSPPHO_RS12935
uniprot id: H6SM14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1150469:RSPPHO RS10070
gene id: 1150469:RSPPHO_RS10070
uniprot id: H6SKJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1150469:RSPPHO RS04920
gene id: 1150469:RSPPHO_RS04920
uniprot id: H6SRJ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1150469:RSPPHO RS08370
gene id: 1150469:RSPPHO_RS08370
uniprot id: H6SJM8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1150469:RSPPHO RS04750
gene id: 1150469:RSPPHO_RS04750
uniprot id: H6SRG3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1150469:RSPPHO RS11795
gene id: 1150469:RSPPHO_RS11795
uniprot id: H6SLG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1150469:RSPPHO RS10025
gene id: 1150469:RSPPHO_RS10025
uniprot id: H6SKI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1150469:RSPPHO RS12375
gene id: 1150469:RSPPHO_RS12375
uniprot id: H6SLS7
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1150469:RSPPHO RS00650
gene id: 1150469:RSPPHO_RS00650
uniprot id: H6SIT4
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1150469:RSPPHO RS07130
gene id: 1150469:RSPPHO_RS07130
uniprot id: H6SIY9
names: Similarity
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS11665
gene id: 1150469:RSPPHO_RS11665
uniprot id: H6SLE0
names: Similarity
messages: Belongs to the glutamate synthase family.

1150469:RSPPHO RS08275
gene id: 1150469:RSPPHO_RS08275
uniprot id: H6SJK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1150469:RSPPHO RS10850
gene id: 1150469:RSPPHO_RS10850
uniprot id: H6SKZ1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1150469:RSPPHO RS17520
gene id: 1150469:RSPPHO_RS17520
uniprot id: H6SQJ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS04380
gene id: 1150469:RSPPHO_RS04380
uniprot id: H6SQV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1150469:RSPPHO RS14300
gene id: 1150469:RSPPHO_RS14300
uniprot id: H6SNG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1150469:RSPPHO RS05800
gene id: 1150469:RSPPHO_RS05800
uniprot id: H6SS15
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS17210
gene id: 1150469:RSPPHO_RS17210
uniprot id: H6SRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1150469:RSPPHO RS15695
gene id: 1150469:RSPPHO_RS15695
uniprot id: H6SQ41
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1150469:RSPPHO RS10290
gene id: 1150469:RSPPHO_RS10290
uniprot id: H6SKN6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

1150469:RSPPHO RS06250
gene id: 1150469:RSPPHO_RS06250
uniprot id: H6SSA2
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1150469:RSPPHO RS17635
gene id: 1150469:RSPPHO_RS17635
uniprot id: H6SS63
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS02620
gene id: 1150469:RSPPHO_RS02620
uniprot id: H6SP23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Membrane

1150469:RSPPHO RS07090
gene id: 1150469:RSPPHO_RS07090
uniprot id: H6SIY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1150469:RSPPHO RS01165
gene id: 1150469:RSPPHO_RS01165
uniprot id: H6SMD1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS10210
gene id: 1150469:RSPPHO_RS10210
uniprot id: H6SKL8
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS02100
gene id: 1150469:RSPPHO_RS02100
uniprot id: H6SNC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1150469:RSPPHO RS03700
gene id: 1150469:RSPPHO_RS03700
uniprot id: H6SQ29
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1150469:RSPPHO RS11505
gene id: 1150469:RSPPHO_RS11505
uniprot id: H6SLB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1150469:RSPPHO RS01825
gene id: 1150469:RSPPHO_RS01825
uniprot id: H6SN73
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1150469:RSPPHO RS06620
gene id: 1150469:RSPPHO_RS06620
uniprot id: H6SSH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1150469:RSPPHO RS10640
gene id: 1150469:RSPPHO_RS10640
uniprot id: H6SKV2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1150469:RSPPHO RS15660
gene id: 1150469:RSPPHO_RS15660
uniprot id: H6SPM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1150469:RSPPHO RS02870
gene id: 1150469:RSPPHO_RS02870
uniprot id: H6SP66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1150469:RSPPHO RS06705
gene id: 1150469:RSPPHO_RS06705
uniprot id: H6SSJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1150469:RSPPHO RS01610
gene id: 1150469:RSPPHO_RS01610
uniprot id: H6SN27
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1150469:RSPPHO RS02105
gene id: 1150469:RSPPHO_RS02105
uniprot id: H6SNS6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1150469:RSPPHO RS02280
gene id: 1150469:RSPPHO_RS02280
uniprot id: H6SNW2
names: Subcellular Location Annotation
messages: Mitochondrion

1150469:RSPPHO RS11820
gene id: 1150469:RSPPHO_RS11820
uniprot id: H6SLG5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS11095
gene id: 1150469:RSPPHO_RS11095
uniprot id: H6SL34
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS18295
gene id: 1150469:RSPPHO_RS18295
uniprot id: H6SN22
names: Similarity
messages: Belongs to the HupF/HypC family.
messages: Belongs to the HupH/HyaF family.

1150469:RSPPHO RS09700
gene id: 1150469:RSPPHO_RS09700
uniprot id: H6SKB8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1150469:RSPPHO RS12745
gene id: 1150469:RSPPHO_RS12745
uniprot id: H6SLY8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1150469:RSPPHO RS00540
gene id: 1150469:RSPPHO_RS00540
uniprot id: H6SIR9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1150469:RSPPHO RS02465
gene id: 1150469:RSPPHO_RS02465
uniprot id: H6SNZ2
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS03225
gene id: 1150469:RSPPHO_RS03225
uniprot id: H6SPT6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS04210
gene id: 1150469:RSPPHO_RS04210
uniprot id: H6SQS6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1150469:RSPPHO RS04880
gene id: 1150469:RSPPHO_RS04880
uniprot id: H6SRI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1150469:RSPPHO RS05315
gene id: 1150469:RSPPHO_RS05315
uniprot id: H6SRS2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1150469:RSPPHO RS03040
gene id: 1150469:RSPPHO_RS03040
uniprot id: H6SPP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS10650
gene id: 1150469:RSPPHO_RS10650
uniprot id: H6SKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS03020
gene id: 1150469:RSPPHO_RS03020
uniprot id: H6SPP4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1150469:RSPPHO RS14125
gene id: 1150469:RSPPHO_RS14125
uniprot id: H6SNC8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1150469:RSPPHO RS01970
gene id: 1150469:RSPPHO_RS01970
uniprot id: H6SN96
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1150469:RSPPHO RS11310
gene id: 1150469:RSPPHO_RS11310
uniprot id: H6SL74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1150469:RSPPHO RS08315
gene id: 1150469:RSPPHO_RS08315
uniprot id: H6SJL7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1150469:RSPPHO RS14455
gene id: 1150469:RSPPHO_RS14455
uniprot id: H6SNJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1150469:RSPPHO RS10860
gene id: 1150469:RSPPHO_RS10860
uniprot id: H6SKZ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1150469:RSPPHO RS05135
gene id: 1150469:RSPPHO_RS05135
uniprot id: H6SRN7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1150469:RSPPHO RS02460
gene id: 1150469:RSPPHO_RS02460
uniprot id: H6SNZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1150469:RSPPHO RS08005
gene id: 1150469:RSPPHO_RS08005
uniprot id: H6SJG1
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

1150469:RSPPHO RS15060
gene id: 1150469:RSPPHO_RS15060
uniprot id: H6SPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS06650
gene id: 1150469:RSPPHO_RS06650
uniprot id: H6SSI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1150469:RSPPHO RS01725
gene id: 1150469:RSPPHO_RS01725
uniprot id: H6SN53
names: Similarity
messages: Belongs to the TrpF family.

1150469:RSPPHO RS05735
gene id: 1150469:RSPPHO_RS05735
uniprot id: H6SS02
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1150469:RSPPHO RS11910
gene id: 1150469:RSPPHO_RS11910
uniprot id: H6SLI1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1150469:RSPPHO RS08320
gene id: 1150469:RSPPHO_RS08320
uniprot id: H6SJL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1150469:RSPPHO RS12205
gene id: 1150469:RSPPHO_RS12205
uniprot id: H6SLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1150469:RSPPHO RS08020
gene id: 1150469:RSPPHO_RS08020
uniprot id: H6SJG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1150469:RSPPHO RS16400
gene id: 1150469:RSPPHO_RS16400
uniprot id: H6SQH3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1150469:RSPPHO RS13435
gene id: 1150469:RSPPHO_RS13435
uniprot id: H6SMJ1
names: Subcellular Location Annotation
messages: Nucleus

1150469:RSPPHO RS06155
gene id: 1150469:RSPPHO_RS06155
uniprot id: H6SS83
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1150469:RSPPHO RS00445
gene id: 1150469:RSPPHO_RS00445
uniprot id: H6SIQ0
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

1150469:RSPPHO RS09075
gene id: 1150469:RSPPHO_RS09075
uniprot id: H6SK02
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS07475
gene id: 1150469:RSPPHO_RS07475
uniprot id: H6SJ59
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1150469:RSPPHO RS09525
gene id: 1150469:RSPPHO_RS09525
uniprot id: H6SK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1150469:RSPPHO RS13165
gene id: 1150469:RSPPHO_RS13165
uniprot id: H6SM61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1150469:RSPPHO RS06630
gene id: 1150469:RSPPHO_RS06630
uniprot id: H6SSH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1150469:RSPPHO RS06640
gene id: 1150469:RSPPHO_RS06640
uniprot id: H6SSH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1150469:RSPPHO RS07115
gene id: 1150469:RSPPHO_RS07115
uniprot id: H6SIY6
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS11350
gene id: 1150469:RSPPHO_RS11350
uniprot id: H6SL81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1150469:RSPPHO RS04435
gene id: 1150469:RSPPHO_RS04435
uniprot id: H6SQX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1150469:RSPPHO RS14070
gene id: 1150469:RSPPHO_RS14070
uniprot id: H6SMW1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1150469:RSPPHO RS09025
gene id: 1150469:RSPPHO_RS09025
uniprot id: H6SJZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1150469:RSPPHO RS17190
gene id: 1150469:RSPPHO_RS17190
uniprot id: H6SRB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1150469:RSPPHO RS00195
gene id: 1150469:RSPPHO_RS00195
uniprot id: H6SIK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1150469:RSPPHO RS09065
gene id: 1150469:RSPPHO_RS09065
uniprot id: H6SK00
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1150469:RSPPHO RS15460
gene id: 1150469:RSPPHO_RS15460
uniprot id: H6SPJ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1150469:RSPPHO RS15380
gene id: 1150469:RSPPHO_RS15380
uniprot id: H6SPH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1150469:RSPPHO RS00950
gene id: 1150469:RSPPHO_RS00950
uniprot id: H6SM90
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS08285
gene id: 1150469:RSPPHO_RS08285
uniprot id: H6SJL1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1150469:RSPPHO RS11165
gene id: 1150469:RSPPHO_RS11165
uniprot id: H6SL47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1150469:RSPPHO RS01645
gene id: 1150469:RSPPHO_RS01645
uniprot id: H6SN34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1150469:RSPPHO RS14315
gene id: 1150469:RSPPHO_RS14315
uniprot id: H6SNG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1150469:RSPPHO RS07300
gene id: 1150469:RSPPHO_RS07300
uniprot id: H6SJ21
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1150469:RSPPHO RS14500
gene id: 1150469:RSPPHO_RS14500
uniprot id: H6SNK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS04035
gene id: 1150469:RSPPHO_RS04035
uniprot id: H6SQP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1150469:RSPPHO RS10145
gene id: 1150469:RSPPHO_RS10145
uniprot id: H6SKK5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1150469:RSPPHO RS01620
gene id: 1150469:RSPPHO_RS01620
uniprot id: H6SN29
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1150469:RSPPHO RS01670
gene id: 1150469:RSPPHO_RS01670
uniprot id: H6SN41
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1150469:RSPPHO RS15100
gene id: 1150469:RSPPHO_RS15100
uniprot id: H6SPC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1150469:RSPPHO RS05225
gene id: 1150469:RSPPHO_RS05225
uniprot id: H6SRQ6
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1150469:RSPPHO RS09500
gene id: 1150469:RSPPHO_RS09500
uniprot id: H6SK77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Membrane
messages: Periplasm

1150469:RSPPHO RS17095
gene id: 1150469:RSPPHO_RS17095
uniprot id: H6SR96
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1150469:RSPPHO RS05675
gene id: 1150469:RSPPHO_RS05675
uniprot id: H6SRZ1
names: Similarity
messages: Belongs to the HesB/IscA family.

1150469:RSPPHO RS06760
gene id: 1150469:RSPPHO_RS06760
uniprot id: H6SSK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1150469:RSPPHO RS09015
gene id: 1150469:RSPPHO_RS09015
uniprot id: H6SJZ1
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1150469:RSPPHO RS03120
gene id: 1150469:RSPPHO_RS03120
uniprot id: H6SPR5
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1150469:RSPPHO RS08295
gene id: 1150469:RSPPHO_RS08295
uniprot id: H6SJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1150469:RSPPHO RS12120
gene id: 1150469:RSPPHO_RS12120
uniprot id: H6SLM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1150469:RSPPHO RS08600
gene id: 1150469:RSPPHO_RS08600
uniprot id: H6SJR8
names: Similarity
messages: Belongs to the GSP E family.

1150469:RSPPHO RS05740
gene id: 1150469:RSPPHO_RS05740
uniprot id: H6SS03
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1150469:RSPPHO RS10420
gene id: 1150469:RSPPHO_RS10420
uniprot id: H6SKQ8
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS16945
gene id: 1150469:RSPPHO_RS16945
uniprot id: H6SR72
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS01290
gene id: 1150469:RSPPHO_RS01290
uniprot id: H6SMF6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1150469:RSPPHO RS07285
gene id: 1150469:RSPPHO_RS07285
uniprot id: H6SJ18
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1150469:RSPPHO RS07685
gene id: 1150469:RSPPHO_RS07685
uniprot id: H6SJA1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1150469:RSPPHO RS01060
gene id: 1150469:RSPPHO_RS01060
uniprot id: H6SMB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1150469:RSPPHO RS07410
gene id: 1150469:RSPPHO_RS07410
uniprot id: H6SJ45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1150469:RSPPHO RS16615
gene id: 1150469:RSPPHO_RS16615
uniprot id: H6SR05
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS15345
gene id: 1150469:RSPPHO_RS15345
uniprot id: H6SPH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1150469:RSPPHO RS09140
gene id: 1150469:RSPPHO_RS09140
uniprot id: H6SK15
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1150469:RSPPHO RS14425
gene id: 1150469:RSPPHO_RS14425
uniprot id: H6SNI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1150469:RSPPHO RS00455
gene id: 1150469:RSPPHO_RS00455
uniprot id: H6SIQ2
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS01985
gene id: 1150469:RSPPHO_RS01985
uniprot id: H6SN99
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS09135
gene id: 1150469:RSPPHO_RS09135
uniprot id: H6SK14
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1150469:RSPPHO RS08085
gene id: 1150469:RSPPHO_RS08085
uniprot id: H6SJH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1150469:RSPPHO RS06410
gene id: 1150469:RSPPHO_RS06410
uniprot id: H6SSD3
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS04270
gene id: 1150469:RSPPHO_RS04270
uniprot id: H6SQT9
names: Similarity
messages: Belongs to the UPF0434 family.

1150469:RSPPHO RS12720
gene id: 1150469:RSPPHO_RS12720
uniprot id: H6SLY2
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1150469:RSPPHO RS04140
gene id: 1150469:RSPPHO_RS04140
uniprot id: H6SQR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1150469:RSPPHO RS07470
gene id: 1150469:RSPPHO_RS07470
uniprot id: H6SJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1150469:RSPPHO RS02860
gene id: 1150469:RSPPHO_RS02860
uniprot id: H6SP63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1150469:RSPPHO RS14460
gene id: 1150469:RSPPHO_RS14460
uniprot id: H6SNJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1150469:RSPPHO RS01145
gene id: 1150469:RSPPHO_RS01145
uniprot id: H6SMC7
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

1150469:RSPPHO RS05850
gene id: 1150469:RSPPHO_RS05850
uniprot id: H6SS25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

1150469:RSPPHO RS05005
gene id: 1150469:RSPPHO_RS05005
uniprot id: H6SRL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1150469:RSPPHO RS11480
gene id: 1150469:RSPPHO_RS11480
uniprot id: H6SLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1150469:RSPPHO RS15795
gene id: 1150469:RSPPHO_RS15795
uniprot id: H6SQ62
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS05085
gene id: 1150469:RSPPHO_RS05085
uniprot id: H6SRM7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1150469:RSPPHO RS16335
gene id: 1150469:RSPPHO_RS16335
uniprot id: H6SQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1150469:RSPPHO RS11170
gene id: 1150469:RSPPHO_RS11170
uniprot id: H6SL48
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1150469:RSPPHO RS00920
gene id: 1150469:RSPPHO_RS00920
uniprot id: H6SM84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1150469:RSPPHO RS05415
gene id: 1150469:RSPPHO_RS05415
uniprot id: H6SRU3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS14245
gene id: 1150469:RSPPHO_RS14245
uniprot id: H6SNF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1150469:RSPPHO RS17150
gene id: 1150469:RSPPHO_RS17150
uniprot id: H6SRA8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1150469:RSPPHO RS16670
gene id: 1150469:RSPPHO_RS16670
uniprot id: H6SR15
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1150469:RSPPHO RS04165
gene id: 1150469:RSPPHO_RS04165
uniprot id: H6SQR8
names: Similarity
messages: Belongs to the SCO1/2 family.

1150469:RSPPHO RS15555
gene id: 1150469:RSPPHO_RS15555
uniprot id: H6SPL3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1150469:RSPPHO RS00300
gene id: 1150469:RSPPHO_RS00300
uniprot id: H6SIM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1150469:RSPPHO RS04150
gene id: 1150469:RSPPHO_RS04150
uniprot id: H6SQR4
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1150469:RSPPHO RS05475
gene id: 1150469:RSPPHO_RS05475
uniprot id: H6SRV5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1150469:RSPPHO RS09550
gene id: 1150469:RSPPHO_RS09550
uniprot id: H6SK87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1150469:RSPPHO RS12320
gene id: 1150469:RSPPHO_RS12320
uniprot id: H6SLR5
names: Similarity
messages: Belongs to the GcvT family.

1150469:RSPPHO RS08725
gene id: 1150469:RSPPHO_RS08725
uniprot id: H6SJU1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1150469:RSPPHO RS02735
gene id: 1150469:RSPPHO_RS02735
uniprot id: H6SP41
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1150469:RSPPHO RS05125
gene id: 1150469:RSPPHO_RS05125
uniprot id: H6SRN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1150469:RSPPHO RS05270
gene id: 1150469:RSPPHO_RS05270
uniprot id: H6SRR4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1150469:RSPPHO RS06645
gene id: 1150469:RSPPHO_RS06645
uniprot id: H6SSH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1150469:RSPPHO RS09095
gene id: 1150469:RSPPHO_RS09095
uniprot id: H6SK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1150469:RSPPHO RS16310
gene id: 1150469:RSPPHO_RS16310
uniprot id: H6SQF6
names: Similarity
messages: Belongs to the UPF0102 family.

1150469:RSPPHO RS07800
gene id: 1150469:RSPPHO_RS07800
uniprot id: H6SJC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1150469:RSPPHO RS04110
gene id: 1150469:RSPPHO_RS04110
uniprot id: H6SQQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1150469:RSPPHO RS06605
gene id: 1150469:RSPPHO_RS06605
uniprot id: H6SSH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1150469:RSPPHO RS09385
gene id: 1150469:RSPPHO_RS09385
uniprot id: H6SK58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS00705
gene id: 1150469:RSPPHO_RS00705
uniprot id: H6SIU6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1150469:RSPPHO RS06010
gene id: 1150469:RSPPHO_RS06010
uniprot id: H6SS52
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1150469:RSPPHO RS06965
gene id: 1150469:RSPPHO_RS06965
uniprot id: H6SIV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1150469:RSPPHO RS15050
gene id: 1150469:RSPPHO_RS15050
uniprot id: H6SPC0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1150469:RSPPHO RS00410
gene id: 1150469:RSPPHO_RS00410
uniprot id: H6SIP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1150469:RSPPHO RS12075
gene id: 1150469:RSPPHO_RS12075
uniprot id: H6SLL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1150469:RSPPHO RS11285
gene id: 1150469:RSPPHO_RS11285
uniprot id: H6SL69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1150469:RSPPHO RS01190
gene id: 1150469:RSPPHO_RS01190
uniprot id: H6SMD5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1150469:RSPPHO RS16545
gene id: 1150469:RSPPHO_RS16545
uniprot id: H6SQZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1150469:RSPPHO RS06680
gene id: 1150469:RSPPHO_RS06680
uniprot id: H6SSI6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1150469:RSPPHO RS04690
gene id: 1150469:RSPPHO_RS04690
uniprot id: H6SRF1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1150469:RSPPHO RS05775
gene id: 1150469:RSPPHO_RS05775
uniprot id: H6SS10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1150469:RSPPHO RS11945
gene id: 1150469:RSPPHO_RS11945
uniprot id: H6SLI8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1150469:RSPPHO RS14470
gene id: 1150469:RSPPHO_RS14470
uniprot id: H6SNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1150469:RSPPHO RS14240
gene id: 1150469:RSPPHO_RS14240
uniprot id: H6SNF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1150469:RSPPHO RS00985
gene id: 1150469:RSPPHO_RS00985
uniprot id: H6SM97
names: Similarity
messages: Belongs to the Skp family.

1150469:RSPPHO RS04470
gene id: 1150469:RSPPHO_RS04470
uniprot id: H6SQX6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1150469:RSPPHO RS07170
gene id: 1150469:RSPPHO_RS07170
uniprot id: H6SIZ7
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS02655
gene id: 1150469:RSPPHO_RS02655
uniprot id: H6SP29
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1150469:RSPPHO RS08530
gene id: 1150469:RSPPHO_RS08530
uniprot id: H6SJQ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1150469:RSPPHO RS02580
gene id: 1150469:RSPPHO_RS02580
uniprot id: H6SP15
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1150469:RSPPHO RS16320
gene id: 1150469:RSPPHO_RS16320
uniprot id: H6SQF8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1150469:RSPPHO RS11600
gene id: 1150469:RSPPHO_RS11600
uniprot id: H6SLD0
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS04990
gene id: 1150469:RSPPHO_RS04990
uniprot id: H6SRK8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1150469:RSPPHO RS09995
gene id: 1150469:RSPPHO_RS09995
uniprot id: H6SKH5
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS02330
gene id: 1150469:RSPPHO_RS02330
uniprot id: H6SNX1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1150469:RSPPHO RS07330
gene id: 1150469:RSPPHO_RS07330
uniprot id: H6SJ28
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1150469:RSPPHO RS17540
gene id: 1150469:RSPPHO_RS17540
uniprot id: H6SQN5
names: Similarity
messages: Belongs to the peptidase S14 family.

1150469:RSPPHO RS01845
gene id: 1150469:RSPPHO_RS01845
uniprot id: H6SN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1150469:RSPPHO RS07320
gene id: 1150469:RSPPHO_RS07320
uniprot id: H6SJ25
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1150469:RSPPHO RS00465
gene id: 1150469:RSPPHO_RS00465
uniprot id: H6SIQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1150469:RSPPHO RS13805
gene id: 1150469:RSPPHO_RS13805
uniprot id: H6SMR1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1150469:RSPPHO RS12815
gene id: 1150469:RSPPHO_RS12815
uniprot id: H6SM02
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1150469:RSPPHO RS10475
gene id: 1150469:RSPPHO_RS10475
uniprot id: H6SKR6
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS06530
gene id: 1150469:RSPPHO_RS06530
uniprot id: H6SSF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1150469:RSPPHO RS09955
gene id: 1150469:RSPPHO_RS09955
uniprot id: H6SKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1150469:RSPPHO RS10655
gene id: 1150469:RSPPHO_RS10655
uniprot id: H6SKV5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1150469:RSPPHO RS00845
gene id: 1150469:RSPPHO_RS00845
uniprot id: H6SII6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1150469:RSPPHO RS12960
gene id: 1150469:RSPPHO_RS12960
uniprot id: H6SM20
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1150469:RSPPHO RS00505
gene id: 1150469:RSPPHO_RS00505
uniprot id: H6SIR2
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS06700
gene id: 1150469:RSPPHO_RS06700
uniprot id: H6SSJ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1150469:RSPPHO RS02680
gene id: 1150469:RSPPHO_RS02680
uniprot id: H6SP34
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS15105
gene id: 1150469:RSPPHO_RS15105
uniprot id: H6SPC9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1150469:RSPPHO RS06635
gene id: 1150469:RSPPHO_RS06635
uniprot id: H6SSH7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1150469:RSPPHO RS14850
gene id: 1150469:RSPPHO_RS14850
uniprot id: H6SNS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1150469:RSPPHO RS03810
gene id: 1150469:RSPPHO_RS03810
uniprot id: H6SQK6
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS00905
gene id: 1150469:RSPPHO_RS00905
uniprot id: H6SM81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1150469:RSPPHO RS11730
gene id: 1150469:RSPPHO_RS11730
uniprot id: H6SLF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1150469:RSPPHO RS08365
gene id: 1150469:RSPPHO_RS08365
uniprot id: H6SJM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1150469:RSPPHO RS13145
gene id: 1150469:RSPPHO_RS13145
uniprot id: H6SM56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1150469:RSPPHO RS12255
gene id: 1150469:RSPPHO_RS12255
uniprot id: H6SLQ3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1150469:RSPPHO RS06765
gene id: 1150469:RSPPHO_RS06765
uniprot id: H6SSK3
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS00805
gene id: 1150469:RSPPHO_RS00805
uniprot id: H6SIH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1150469:RSPPHO RS05130
gene id: 1150469:RSPPHO_RS05130
uniprot id: H6SRN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1150469:RSPPHO RS02240
gene id: 1150469:RSPPHO_RS02240
uniprot id: H6SNV4
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1150469:RSPPHO RS04105
gene id: 1150469:RSPPHO_RS04105
uniprot id: H6SQQ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1150469:RSPPHO RS07735
gene id: 1150469:RSPPHO_RS07735
uniprot id: H6SJB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1150469:RSPPHO RS03695
gene id: 1150469:RSPPHO_RS03695
uniprot id: H6SQ28
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1150469:RSPPHO RS06785
gene id: 1150469:RSPPHO_RS06785
uniprot id: H6SSK7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1150469:RSPPHO RS12435
gene id: 1150469:RSPPHO_RS12435
uniprot id: H6SLT7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1150469:RSPPHO RS09440
gene id: 1150469:RSPPHO_RS09440
uniprot id: H6SK66
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1150469:RSPPHO RS02600
gene id: 1150469:RSPPHO_RS02600
uniprot id: H6SP19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1150469:RSPPHO RS13515
gene id: 1150469:RSPPHO_RS13515
uniprot id: H6SMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1150469:RSPPHO RS06075
gene id: 1150469:RSPPHO_RS06075
uniprot id: H6SS65
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from FixA/FixB and reduces a quinone.
messages: Part of an electron transfer system.

1150469:RSPPHO RS16140
gene id: 1150469:RSPPHO_RS16140
uniprot id: H6SQD0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS07340
gene id: 1150469:RSPPHO_RS07340
uniprot id: H6SJ30
names: Similarity
messages: Belongs to the fabD family.

1150469:RSPPHO RS02785
gene id: 1150469:RSPPHO_RS02785
uniprot id: H6SP51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1150469:RSPPHO RS04060
gene id: 1150469:RSPPHO_RS04060
uniprot id: H6SQQ0
names: Similarity
messages: Belongs to the peptidase M16 family.

1150469:RSPPHO RS04700
gene id: 1150469:RSPPHO_RS04700
uniprot id: H6SRF3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1150469:RSPPHO RS01395
gene id: 1150469:RSPPHO_RS01395
uniprot id: H6SMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1150469:RSPPHO RS04600
gene id: 1150469:RSPPHO_RS04600
uniprot id: H6SRD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS15830
gene id: 1150469:RSPPHO_RS15830
uniprot id: H6SQ69
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS17180
gene id: 1150469:RSPPHO_RS17180
uniprot id: H6SRB5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1150469:RSPPHO RS14640
gene id: 1150469:RSPPHO_RS14640
uniprot id: H6SNN3
names: Subcellular Location Annotation
messages: Cell inner membrane

1150469:RSPPHO RS14360
gene id: 1150469:RSPPHO_RS14360
uniprot id: H6SNH6
names: Function
messages: Multidrug efflux pump.

1150469:RSPPHO RS12740
gene id: 1150469:RSPPHO_RS12740
uniprot id: H6SLY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1150469:RSPPHO RS00875
gene id: 1150469:RSPPHO_RS00875
uniprot id: H6SIJ2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1150469:RSPPHO RS12995
gene id: 1150469:RSPPHO_RS12995
uniprot id: H6SM27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1150469:RSPPHO RS10205
gene id: 1150469:RSPPHO_RS10205
uniprot id: H6SKL7
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS10350
gene id: 1150469:RSPPHO_RS10350
uniprot id: H6SKP8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1150469:RSPPHO RS04970
gene id: 1150469:RSPPHO_RS04970
uniprot id: H6SRK4
names: Similarity
messages: Belongs to the UPF0174 family.

1150469:RSPPHO RS16950
gene id: 1150469:RSPPHO_RS16950
uniprot id: H6SR73
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1150469:RSPPHO RS15300
gene id: 1150469:RSPPHO_RS15300
uniprot id: H6SPG4
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS01035
gene id: 1150469:RSPPHO_RS01035
uniprot id: H6SMA7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1150469:RSPPHO RS16880
gene id: 1150469:RSPPHO_RS16880
uniprot id: H6SR60
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1150469:RSPPHO RS18195
gene id: 1150469:RSPPHO_RS18195
uniprot id: H6SQ61
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS17770
gene id: 1150469:RSPPHO_RS17770
uniprot id: H6SJW2
names: Subcellular Location Annotation
messages: Cell inner membrane

1150469:RSPPHO RS14815
gene id: 1150469:RSPPHO_RS14815
uniprot id: H6SNR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

1150469:RSPPHO RS09795
gene id: 1150469:RSPPHO_RS09795
uniprot id: H6SKD6
names: Similarity
messages: Belongs to the YggT family.

1150469:RSPPHO RS16960
gene id: 1150469:RSPPHO_RS16960
uniprot id: H6SR75
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1150469:RSPPHO RS01455
gene id: 1150469:RSPPHO_RS01455
uniprot id: H6SMZ7
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1150469:RSPPHO RS03185
gene id: 1150469:RSPPHO_RS03185
uniprot id: H6SPS8
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1150469:RSPPHO RS07390
gene id: 1150469:RSPPHO_RS07390
uniprot id: H6SJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1150469:RSPPHO RS11445
gene id: 1150469:RSPPHO_RS11445
uniprot id: H6SLA1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1150469:RSPPHO RS17125
gene id: 1150469:RSPPHO_RS17125
uniprot id: H6SRA3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1150469:RSPPHO RS16895
gene id: 1150469:RSPPHO_RS16895
uniprot id: H6SR63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS00935
gene id: 1150469:RSPPHO_RS00935
uniprot id: H6SM87
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1150469:RSPPHO RS02745
gene id: 1150469:RSPPHO_RS02745
uniprot id: H6SP43
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Hexamer of two alpha, two beta, and two delta chains.

1150469:RSPPHO RS14890
gene id: 1150469:RSPPHO_RS14890
uniprot id: H6SP87
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1150469:RSPPHO RS07985
gene id: 1150469:RSPPHO_RS07985
uniprot id: H6SJF7
names: Function
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Cell inner membrane
messages: Membrane

1150469:RSPPHO RS21255
gene id: 1150469:RSPPHO_RS21255
uniprot id: H6SMH8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS19950
gene id: 1150469:RSPPHO_RS19950
uniprot id: H6SKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

1150469:RSPPHO RS08825
gene id: 1150469:RSPPHO_RS08825
uniprot id: H6SJV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1150469:RSPPHO RS09570
gene id: 1150469:RSPPHO_RS09570
uniprot id: H6SK92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1150469:RSPPHO RS16905
gene id: 1150469:RSPPHO_RS16905
uniprot id: H6SR65
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1150469:RSPPHO RS00250
gene id: 1150469:RSPPHO_RS00250
uniprot id: H6SIL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1150469:RSPPHO RS03130
gene id: 1150469:RSPPHO_RS03130
uniprot id: H6SPR7
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1150469:RSPPHO RS08745
gene id: 1150469:RSPPHO_RS08745
uniprot id: H6SJU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1150469:RSPPHO RS04645
gene id: 1150469:RSPPHO_RS04645
uniprot id: H6SRE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1150469:RSPPHO RS07490
gene id: 1150469:RSPPHO_RS07490
uniprot id: H6SJ62
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1150469:RSPPHO RS13670
gene id: 1150469:RSPPHO_RS13670
uniprot id: H6SMN2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1150469:RSPPHO RS00850
gene id: 1150469:RSPPHO_RS00850
uniprot id: H6SII7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1150469:RSPPHO RS11385
gene id: 1150469:RSPPHO_RS11385
uniprot id: H6SL89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1150469:RSPPHO RS02780
gene id: 1150469:RSPPHO_RS02780
uniprot id: H6SP50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1150469:RSPPHO RS12265
gene id: 1150469:RSPPHO_RS12265
uniprot id: H6SLQ4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1150469:RSPPHO RS04070
gene id: 1150469:RSPPHO_RS04070
uniprot id: H6SQQ1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1150469:RSPPHO RS10795
gene id: 1150469:RSPPHO_RS10795
uniprot id: H6SKY0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1150469:RSPPHO RS10185
gene id: 1150469:RSPPHO_RS10185
uniprot id: H6SKL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1150469:RSPPHO RS06660
gene id: 1150469:RSPPHO_RS06660
uniprot id: H6SSI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1150469:RSPPHO RS05055
gene id: 1150469:RSPPHO_RS05055
uniprot id: H6SRM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1150469:RSPPHO RS15280
gene id: 1150469:RSPPHO_RS15280
uniprot id: H6SPG0
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS07565
gene id: 1150469:RSPPHO_RS07565
uniprot id: H6SJ78
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1150469:RSPPHO RS02925
gene id: 1150469:RSPPHO_RS02925
uniprot id: H6SP77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1150469:RSPPHO RS05745
gene id: 1150469:RSPPHO_RS05745
uniprot id: H6SS04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1150469:RSPPHO RS01750
gene id: 1150469:RSPPHO_RS01750
uniprot id: H6SN59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1150469:RSPPHO RS00895
gene id: 1150469:RSPPHO_RS00895
uniprot id: H6SIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1150469:RSPPHO RS06595
gene id: 1150469:RSPPHO_RS06595
uniprot id: H6SSG9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1150469:RSPPHO RS13215
gene id: 1150469:RSPPHO_RS13215
uniprot id: H6SM71
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1150469:RSPPHO RS07225
gene id: 1150469:RSPPHO_RS07225
uniprot id: H6SJ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1150469:RSPPHO RS16925
gene id: 1150469:RSPPHO_RS16925
uniprot id: H6SR69
names: Function
names: Similarity
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.

1150469:RSPPHO RS14805
gene id: 1150469:RSPPHO_RS14805
uniprot id: H6SNR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS08420
gene id: 1150469:RSPPHO_RS08420
uniprot id: H6SJN8
names: Similarity
messages: Belongs to the PRORSD1 family.

1150469:RSPPHO RS14955
gene id: 1150469:RSPPHO_RS14955
uniprot id: H6SPA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1150469:RSPPHO RS03790
gene id: 1150469:RSPPHO_RS03790
uniprot id: H6SQK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1150469:RSPPHO RS20540
gene id: 1150469:RSPPHO_RS20540
uniprot id: H6SK68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1150469:RSPPHO RS14945
gene id: 1150469:RSPPHO_RS14945
uniprot id: H6SP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS02145
gene id: 1150469:RSPPHO_RS02145
uniprot id: H6SNT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1150469:RSPPHO RS06035
gene id: 1150469:RSPPHO_RS06035
uniprot id: H6SS57
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1150469:RSPPHO RS08240
gene id: 1150469:RSPPHO_RS08240
uniprot id: H6SJK2
names: Similarity
messages: Belongs to the peptidase S11 family.

1150469:RSPPHO RS12750
gene id: 1150469:RSPPHO_RS12750
uniprot id: H6SLY9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1150469:RSPPHO RS05155
gene id: 1150469:RSPPHO_RS05155
uniprot id: H6SRP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1150469:RSPPHO RS17110
gene id: 1150469:RSPPHO_RS17110
uniprot id: H6SR99
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1150469:RSPPHO RS16900
gene id: 1150469:RSPPHO_RS16900
uniprot id: H6SR64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS08450
gene id: 1150469:RSPPHO_RS08450
uniprot id: H6SJP3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS08985
gene id: 1150469:RSPPHO_RS08985
uniprot id: H6SJY6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1150469:RSPPHO RS13505
gene id: 1150469:RSPPHO_RS13505
uniprot id: H6SMK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1150469:RSPPHO RS10890
gene id: 1150469:RSPPHO_RS10890
uniprot id: H6SKZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS15440
gene id: 1150469:RSPPHO_RS15440
uniprot id: H6SPI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1150469:RSPPHO RS03600
gene id: 1150469:RSPPHO_RS03600
uniprot id: H6SQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1150469:RSPPHO RS15165
gene id: 1150469:RSPPHO_RS15165
uniprot id: H6SPE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1150469:RSPPHO RS12635
gene id: 1150469:RSPPHO_RS12635
uniprot id: H6SLW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1150469:RSPPHO RS08690
gene id: 1150469:RSPPHO_RS08690
uniprot id: H6SJT4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1150469:RSPPHO RS08050
gene id: 1150469:RSPPHO_RS08050
uniprot id: H6SJH0
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS19990
gene id: 1150469:RSPPHO_RS19990
uniprot id: H6SL52
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS08640
gene id: 1150469:RSPPHO_RS08640
uniprot id: H6SJS7
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1150469:RSPPHO RS17675
gene id: 1150469:RSPPHO_RS17675
uniprot id: H6SSL7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS00815
gene id: 1150469:RSPPHO_RS00815
uniprot id: H6SII1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1150469:RSPPHO RS16280
gene id: 1150469:RSPPHO_RS16280
uniprot id: H6SQF0
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1150469:RSPPHO RS03560
gene id: 1150469:RSPPHO_RS03560
uniprot id: H6SQ02
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1150469:RSPPHO RS13485
gene id: 1150469:RSPPHO_RS13485
uniprot id: H6SMK1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1150469:RSPPHO RS05445
gene id: 1150469:RSPPHO_RS05445
uniprot id: H6SRU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS09490
gene id: 1150469:RSPPHO_RS09490
uniprot id: H6SK75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1150469:RSPPHO RS01975
gene id: 1150469:RSPPHO_RS01975
uniprot id: H6SN97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1150469:RSPPHO RS04275
gene id: 1150469:RSPPHO_RS04275
uniprot id: H6SQU0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1150469:RSPPHO RS14260
gene id: 1150469:RSPPHO_RS14260
uniprot id: H6SNF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS16350
gene id: 1150469:RSPPHO_RS16350
uniprot id: H6SQG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1150469:RSPPHO RS10425
gene id: 1150469:RSPPHO_RS10425
uniprot id: H6SKQ9
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS10835
gene id: 1150469:RSPPHO_RS10835
uniprot id: H6SKY8
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS20940
gene id: 1150469:RSPPHO_RS20940
uniprot id: H6SJ07
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS07805
gene id: 1150469:RSPPHO_RS07805
uniprot id: H6SJC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1150469:RSPPHO RS02125
gene id: 1150469:RSPPHO_RS02125
uniprot id: H6SNT0
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS07990
gene id: 1150469:RSPPHO_RS07990
uniprot id: H6SJF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

1150469:RSPPHO RS10030
gene id: 1150469:RSPPHO_RS10030
uniprot id: H6SKI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1150469:RSPPHO RS02755
gene id: 1150469:RSPPHO_RS02755
uniprot id: H6SP45
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1150469:RSPPHO RS14465
gene id: 1150469:RSPPHO_RS14465
uniprot id: H6SNJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1150469:RSPPHO RS01460
gene id: 1150469:RSPPHO_RS01460
uniprot id: H6SMZ8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS07100
gene id: 1150469:RSPPHO_RS07100
uniprot id: H6SIY3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS11520
gene id: 1150469:RSPPHO_RS11520
uniprot id: H6SLB4
names: Subcellular Location Annotation
messages: Cytoplasm

1150469:RSPPHO RS06110
gene id: 1150469:RSPPHO_RS06110
uniprot id: H6SS72
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS20820
gene id: 1150469:RSPPHO_RS20820
uniprot id: H6SPQ1
names: Subcellular Location Annotation
messages: Cell membrane

1150469:RSPPHO RS07575
gene id: 1150469:RSPPHO_RS07575
uniprot id: H6SJ80
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1150469:RSPPHO RS06625
gene id: 1150469:RSPPHO_RS06625
uniprot id: H6SSH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1150469:RSPPHO RS12055
gene id: 1150469:RSPPHO_RS12055
uniprot id: H6SLL0
names: Similarity
messages: Belongs to the autoinducer synthase family.

1150469:RSPPHO RS05295
gene id: 1150469:RSPPHO_RS05295
uniprot id: H6SRR8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1150469:RSPPHO RS11645
gene id: 1150469:RSPPHO_RS11645
uniprot id: H6SLD6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1150469:RSPPHO RS07015
gene id: 1150469:RSPPHO_RS07015
uniprot id: H6SIW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1150469:RSPPHO RS13860
gene id: 1150469:RSPPHO_RS13860
uniprot id: H6SMS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1150469:RSPPHO RS09035
gene id: 1150469:RSPPHO_RS09035
uniprot id: H6SJZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1150469:RSPPHO RS04775
gene id: 1150469:RSPPHO_RS04775
uniprot id: H6SRG9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1150469:RSPPHO RS08375
gene id: 1150469:RSPPHO_RS08375
uniprot id: H6SJM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1150469:RSPPHO RS06255
gene id: 1150469:RSPPHO_RS06255
uniprot id: H6SSA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1150469:RSPPHO RS02805
gene id: 1150469:RSPPHO_RS02805
uniprot id: H6SP55
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS07275
gene id: 1150469:RSPPHO_RS07275
uniprot id: H6SJ16
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1150469:RSPPHO RS15655
gene id: 1150469:RSPPHO_RS15655
uniprot id: H6SPM8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1150469:RSPPHO RS13885
gene id: 1150469:RSPPHO_RS13885
uniprot id: H6SMS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1150469:RSPPHO RS07795
gene id: 1150469:RSPPHO_RS07795
uniprot id: H6SJC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1150469:RSPPHO RS03555
gene id: 1150469:RSPPHO_RS03555
uniprot id: H6SQ01
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1150469:RSPPHO RS16115
gene id: 1150469:RSPPHO_RS16115
uniprot id: H6SQC6
names: Similarity
messages: Belongs to the hemerythrin family.

1150469:RSPPHO RS13355
gene id: 1150469:RSPPHO_RS13355
uniprot id: H6SMH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1150469:RSPPHO RS09130
gene id: 1150469:RSPPHO_RS09130
uniprot id: H6SK13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1150469:RSPPHO RS06655
gene id: 1150469:RSPPHO_RS06655
uniprot id: H6SSI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1150469:RSPPHO RS01105
gene id: 1150469:RSPPHO_RS01105
uniprot id: H6SMB9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1150469:RSPPHO RS16055
gene id: 1150469:RSPPHO_RS16055
uniprot id: H6SQB4
names: Similarity
messages: Belongs to the HesB/IscA family.

1150469:RSPPHO RS02210
gene id: 1150469:RSPPHO_RS02210
uniprot id: H6SNU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1150469:RSPPHO RS11375
gene id: 1150469:RSPPHO_RS11375
uniprot id: H6SL87
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1150469:RSPPHO RS02825
gene id: 1150469:RSPPHO_RS02825
uniprot id: H6SP59
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1150469:RSPPHO RS07400
gene id: 1150469:RSPPHO_RS07400
uniprot id: H6SJ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1150469:RSPPHO RS13015
gene id: 1150469:RSPPHO_RS13015
uniprot id: H6SM31
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1150469:RSPPHO RS03475
gene id: 1150469:RSPPHO_RS03475
uniprot id: H6SPY5
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

1150469:RSPPHO RS02740
gene id: 1150469:RSPPHO_RS02740
uniprot id: H6SP42
names: Function
names: Subunit
messages: Hexamer of two alpha, two beta, and two delta chains.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.

1150469:RSPPHO RS04955
gene id: 1150469:RSPPHO_RS04955
uniprot id: H6SRK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1150469:RSPPHO RS00265
gene id: 1150469:RSPPHO_RS00265
uniprot id: H6SIL6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1150469:RSPPHO RS10700
gene id: 1150469:RSPPHO_RS10700
uniprot id: H6SKW4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1150469:RSPPHO RS04545
gene id: 1150469:RSPPHO_RS04545
uniprot id: H6SQZ1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1150469:RSPPHO RS07250
gene id: 1150469:RSPPHO_RS07250
uniprot id: H6SJ11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS00305
gene id: 1150469:RSPPHO_RS00305
uniprot id: H6SIM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1150469:RSPPHO RS02625
gene id: 1150469:RSPPHO_RS02625
uniprot id: H6SP24
names: Similarity
messages: Belongs to the peptidase S13 family.

1150469:RSPPHO RS11055
gene id: 1150469:RSPPHO_RS11055
uniprot id: H6SL27
names: Similarity
messages: Belongs to the peptidase S41A family.

1150469:RSPPHO RS03410
gene id: 1150469:RSPPHO_RS03410
uniprot id: H6SPX2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1150469:RSPPHO RS07335
gene id: 1150469:RSPPHO_RS07335
uniprot id: H6SJ29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1150469:RSPPHO RS06665
gene id: 1150469:RSPPHO_RS06665
uniprot id: H6SSI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1150469:RSPPHO RS15385
gene id: 1150469:RSPPHO_RS15385
uniprot id: H6SPH9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1150469:RSPPHO RS06345
gene id: 1150469:RSPPHO_RS06345
uniprot id: H6SSC0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1150469:RSPPHO RS04100
gene id: 1150469:RSPPHO_RS04100
uniprot id: H6SQQ7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS08715
gene id: 1150469:RSPPHO_RS08715
uniprot id: H6SJT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1150469:RSPPHO RS07405
gene id: 1150469:RSPPHO_RS07405
uniprot id: H6SJ44
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1150469:RSPPHO RS17380
gene id: 1150469:RSPPHO_RS17380
uniprot id: H6SN75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1150469:RSPPHO RS09710
gene id: 1150469:RSPPHO_RS09710
uniprot id: H6SKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1150469:RSPPHO RS13445
gene id: 1150469:RSPPHO_RS13445
uniprot id: H6SMJ3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1150469:RSPPHO RS12965
gene id: 1150469:RSPPHO_RS12965
uniprot id: H6SM21
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1150469:RSPPHO RS16220
gene id: 1150469:RSPPHO_RS16220
uniprot id: H6SQE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1150469:RSPPHO RS16060
gene id: 1150469:RSPPHO_RS16060
uniprot id: H6SQB5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1150469:RSPPHO RS15010
gene id: 1150469:RSPPHO_RS15010
uniprot id: H6SPB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1150469:RSPPHO RS07200
gene id: 1150469:RSPPHO_RS07200
uniprot id: H6SJ01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1150469:RSPPHO RS12580
gene id: 1150469:RSPPHO_RS12580
uniprot id: H6SLV7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1150469:RSPPHO RS02960
gene id: 1150469:RSPPHO_RS02960
uniprot id: H6SPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1150469:RSPPHO RS14910
gene id: 1150469:RSPPHO_RS14910
uniprot id: H6SP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

1150469:RSPPHO RS12565
gene id: 1150469:RSPPHO_RS12565
uniprot id: H6SLV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS14440
gene id: 1150469:RSPPHO_RS14440
uniprot id: H6SNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1150469:RSPPHO RS07995
gene id: 1150469:RSPPHO_RS07995
uniprot id: H6SJF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

1150469:RSPPHO RS13410
gene id: 1150469:RSPPHO_RS13410
uniprot id: H6SMI6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1150469:RSPPHO RS03530
gene id: 1150469:RSPPHO_RS03530
uniprot id: H6SPZ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1150469:RSPPHO RS02290
gene id: 1150469:RSPPHO_RS02290
uniprot id: H6SNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1150469:RSPPHO RS15160
gene id: 1150469:RSPPHO_RS15160
uniprot id: H6SPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1150469:RSPPHO RS02275
gene id: 1150469:RSPPHO_RS02275
uniprot id: H6SNW1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1150469:RSPPHO RS07265
gene id: 1150469:RSPPHO_RS07265
uniprot id: H6SJ14
names: Similarity
messages: Belongs to the universal stress protein A family.

1150469:RSPPHO RS06600
gene id: 1150469:RSPPHO_RS06600
uniprot id: H6SSH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1150469:RSPPHO RS03030
gene id: 1150469:RSPPHO_RS03030
uniprot id: H6SPP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1150469:RSPPHO RS10130
gene id: 1150469:RSPPHO_RS10130
uniprot id: H6SKK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1150469:RSPPHO RS00995
gene id: 1150469:RSPPHO_RS00995
uniprot id: H6SM99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1150469:RSPPHO RS15585
gene id: 1150469:RSPPHO_RS15585
uniprot id: H6SPL6
names: Similarity
messages: Belongs to the MEMO1 family.

1150469:RSPPHO RS12945
gene id: 1150469:RSPPHO_RS12945
uniprot id: H6SM16
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS10775
gene id: 1150469:RSPPHO_RS10775
uniprot id: H6SKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1150469:RSPPHO RS00260
gene id: 1150469:RSPPHO_RS00260
uniprot id: H6SIL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1150469:RSPPHO RS10905
gene id: 1150469:RSPPHO_RS10905
uniprot id: H6SL02
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1150469:RSPPHO RS08040
gene id: 1150469:RSPPHO_RS08040
uniprot id: H6SJG8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1150469:RSPPHO RS06720
gene id: 1150469:RSPPHO_RS06720
uniprot id: H6SSJ4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1150469:RSPPHO RS06205
gene id: 1150469:RSPPHO_RS06205
uniprot id: H6SS93
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1150469:RSPPHO RS07570
gene id: 1150469:RSPPHO_RS07570
uniprot id: H6SJ79
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS13950
gene id: 1150469:RSPPHO_RS13950
uniprot id: H6SMT7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1150469:RSPPHO RS05360
gene id: 1150469:RSPPHO_RS05360
uniprot id: H6SRT2
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1150469:RSPPHO RS13785
gene id: 1150469:RSPPHO_RS13785
uniprot id: H6SMQ7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1150469:RSPPHO RS07975
gene id: 1150469:RSPPHO_RS07975
uniprot id: H6SJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Cellular chromatophore membrane
messages: Membrane
messages: Reaction center is composed of four bacteriochlorophylls, two bacteriopheophytins, two ubiquinones, one iron, and highly hydrophobic polypeptide chains.
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

1150469:RSPPHO RS07515
gene id: 1150469:RSPPHO_RS07515
uniprot id: H6SJ68
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1150469:RSPPHO RS01230
gene id: 1150469:RSPPHO_RS01230
uniprot id: H6SME3
names: Subcellular Location Annotation
messages: Periplasm

1150469:RSPPHO RS14485
gene id: 1150469:RSPPHO_RS14485
uniprot id: H6SNK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1150469:RSPPHO RS10085
gene id: 1150469:RSPPHO_RS10085
uniprot id: H6SKJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1150469:RSPPHO RS01595
gene id: 1150469:RSPPHO_RS01595
uniprot id: H6SN23
names: Similarity
messages: Belongs to the peptidase A31 family.

1150469:RSPPHO RS04055
gene id: 1150469:RSPPHO_RS04055
uniprot id: H6SQP9
names: Similarity
messages: Belongs to the threonine synthase family.

1150469:RSPPHO RS04170
gene id: 1150469:RSPPHO_RS04170
uniprot id: H6SQR9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1150469:RSPPHO RS10300
gene id: 1150469:RSPPHO_RS10300
uniprot id: H6SKN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1150469:RSPPHO RS12305
gene id: 1150469:RSPPHO_RS12305
uniprot id: H6SLR2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1150469:RSPPHO RS16680
gene id: 1150469:RSPPHO_RS16680
uniprot id: H6SR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1150469:RSPPHO RS15745
gene id: 1150469:RSPPHO_RS15745
uniprot id: H6SQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1150469:RSPPHO RS08395
gene id: 1150469:RSPPHO_RS08395
uniprot id: H6SJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1150469:RSPPHO RS15945
gene id: 1150469:RSPPHO_RS15945
uniprot id: H6SQ89
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS05350
gene id: 1150469:RSPPHO_RS05350
uniprot id: H6SRT0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1150469:RSPPHO RS11825
gene id: 1150469:RSPPHO_RS11825
uniprot id: H6SLG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1150469:RSPPHO RS13055
gene id: 1150469:RSPPHO_RS13055
uniprot id: H6SM37
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1150469:RSPPHO RS09715
gene id: 1150469:RSPPHO_RS09715
uniprot id: H6SKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1150469:RSPPHO RS16785
gene id: 1150469:RSPPHO_RS16785
uniprot id: H6SR38
names: Similarity
messages: Belongs to the aldose epimerase family.

1150469:RSPPHO RS16415
gene id: 1150469:RSPPHO_RS16415
uniprot id: H6SQH6
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

1150469:RSPPHO RS03430
gene id: 1150469:RSPPHO_RS03430
uniprot id: H6SPX6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS05910
gene id: 1150469:RSPPHO_RS05910
uniprot id: H6SS37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1150469:RSPPHO RS07725
gene id: 1150469:RSPPHO_RS07725
uniprot id: H6SJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1150469:RSPPHO RS14205
gene id: 1150469:RSPPHO_RS14205
uniprot id: H6SNE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1150469:RSPPHO RS00200
gene id: 1150469:RSPPHO_RS00200
uniprot id: H6SIK5
names: Similarity
messages: Belongs to the peptidase S41A family.

1150469:RSPPHO RS13000
gene id: 1150469:RSPPHO_RS13000
uniprot id: H6SM28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1150469:RSPPHO RS17195
gene id: 1150469:RSPPHO_RS17195
uniprot id: H6SRB8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS07635
gene id: 1150469:RSPPHO_RS07635
uniprot id: H6SJ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1150469:RSPPHO RS11300
gene id: 1150469:RSPPHO_RS11300
uniprot id: H6SL72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1150469:RSPPHO RS00180
gene id: 1150469:RSPPHO_RS00180
uniprot id: H6SIK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1150469:RSPPHO RS08550
gene id: 1150469:RSPPHO_RS08550
uniprot id: H6SJR0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1150469:RSPPHO RS06020
gene id: 1150469:RSPPHO_RS06020
uniprot id: H6SS54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS05630
gene id: 1150469:RSPPHO_RS05630
uniprot id: H6SRY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1150469:RSPPHO RS14980
gene id: 1150469:RSPPHO_RS14980
uniprot id: H6SPA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1150469:RSPPHO RS06360
gene id: 1150469:RSPPHO_RS06360
uniprot id: H6SSC3
names: Function
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

1150469:RSPPHO RS00710
gene id: 1150469:RSPPHO_RS00710
uniprot id: H6SIU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1150469:RSPPHO RS07660
gene id: 1150469:RSPPHO_RS07660
uniprot id: H6SJ99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1150469:RSPPHO RS03770
gene id: 1150469:RSPPHO_RS03770
uniprot id: H6SQJ8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1150469:RSPPHO RS07720
gene id: 1150469:RSPPHO_RS07720
uniprot id: H6SJA7
names: Similarity
messages: Belongs to the histone deacetylase family.

1150469:RSPPHO RS06015
gene id: 1150469:RSPPHO_RS06015
uniprot id: H6SS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1150469:RSPPHO RS00255
gene id: 1150469:RSPPHO_RS00255
uniprot id: H6SIL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1150469:RSPPHO RS15035
gene id: 1150469:RSPPHO_RS15035
uniprot id: H6SPB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1150469:RSPPHO RS08385
gene id: 1150469:RSPPHO_RS08385
uniprot id: H6SJN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1150469:RSPPHO RS06090
gene id: 1150469:RSPPHO_RS06090
uniprot id: H6SS68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

1150469:RSPPHO RS00675
gene id: 1150469:RSPPHO_RS00675
uniprot id: H6SIT9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1150469:RSPPHO RS09470
gene id: 1150469:RSPPHO_RS09470
uniprot id: H6SK71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1150469:RSPPHO RS01005
gene id: 1150469:RSPPHO_RS01005
uniprot id: H6SMA1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1150469:RSPPHO RS10080
gene id: 1150469:RSPPHO_RS10080
uniprot id: H6SKJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1150469:RSPPHO RS01390
gene id: 1150469:RSPPHO_RS01390
uniprot id: H6SMY4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1150469:RSPPHO RS11545
gene id: 1150469:RSPPHO_RS11545
uniprot id: H6SLB9
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS10660
gene id: 1150469:RSPPHO_RS10660
uniprot id: H6SKV6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1150469:RSPPHO RS15650
gene id: 1150469:RSPPHO_RS15650
uniprot id: H6SPM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1150469:RSPPHO RS06165
gene id: 1150469:RSPPHO_RS06165
uniprot id: H6SS85
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1150469:RSPPHO RS02675
gene id: 1150469:RSPPHO_RS02675
uniprot id: H6SP33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1150469:RSPPHO RS06610
gene id: 1150469:RSPPHO_RS06610
uniprot id: H6SSH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1150469:RSPPHO RS03190
gene id: 1150469:RSPPHO_RS03190
uniprot id: H6SPS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1150469:RSPPHO RS12080
gene id: 1150469:RSPPHO_RS12080
uniprot id: H6SLL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1150469:RSPPHO RS10685
gene id: 1150469:RSPPHO_RS10685
uniprot id: H6SKW1
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1150469:RSPPHO RS13380
gene id: 1150469:RSPPHO_RS13380
uniprot id: H6SMI0
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS14305
gene id: 1150469:RSPPHO_RS14305
uniprot id: H6SNG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1150469:RSPPHO RS09835
gene id: 1150469:RSPPHO_RS09835
uniprot id: H6SKE5
names: Similarity
messages: Belongs to the UPF0386 family.

1150469:RSPPHO RS03370
gene id: 1150469:RSPPHO_RS03370
uniprot id: H6SPW1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1150469:RSPPHO RS05330
gene id: 1150469:RSPPHO_RS05330
uniprot id: H6SRS6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1150469:RSPPHO RS02040
gene id: 1150469:RSPPHO_RS02040
uniprot id: H6SNA8
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1150469:RSPPHO RS09725
gene id: 1150469:RSPPHO_RS09725
uniprot id: H6SKC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1150469:RSPPHO RS07595
gene id: 1150469:RSPPHO_RS07595
uniprot id: H6SJ84
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1150469:RSPPHO RS00375
gene id: 1150469:RSPPHO_RS00375
uniprot id: H6SIN7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1150469:RSPPHO RS11360
gene id: 1150469:RSPPHO_RS11360
uniprot id: H6SL84
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1150469:RSPPHO RS00275
gene id: 1150469:RSPPHO_RS00275
uniprot id: H6SIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1150469:RSPPHO RS08990
gene id: 1150469:RSPPHO_RS08990
uniprot id: H6SJY7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1150469:RSPPHO RS13190
gene id: 1150469:RSPPHO_RS13190
uniprot id: H6SM66
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1150469:RSPPHO RS13635
gene id: 1150469:RSPPHO_RS13635
uniprot id: H6SMM4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1150469:RSPPHO RS10505
gene id: 1150469:RSPPHO_RS10505
uniprot id: H6SKS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1150469:RSPPHO RS07525
gene id: 1150469:RSPPHO_RS07525
uniprot id: H6SJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1150469:RSPPHO RS05000
gene id: 1150469:RSPPHO_RS05000
uniprot id: H6SRL0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1150469:RSPPHO RS03140
gene id: 1150469:RSPPHO_RS03140
uniprot id: H6SPR9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1150469:RSPPHO RS10325
gene id: 1150469:RSPPHO_RS10325
uniprot id: H6SKP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1150469:RSPPHO RS14445
gene id: 1150469:RSPPHO_RS14445
uniprot id: H6SNJ3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1150469:RSPPHO RS09540
gene id: 1150469:RSPPHO_RS09540
uniprot id: H6SK85
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1150469:RSPPHO RS13070
gene id: 1150469:RSPPHO_RS13070
uniprot id: H6SM40
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1150469:RSPPHO RS03420
gene id: 1150469:RSPPHO_RS03420
uniprot id: H6SPX4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1150469:RSPPHO RS02610
gene id: 1150469:RSPPHO_RS02610
uniprot id: H6SP21
names: Similarity
messages: Belongs to the glutamate synthase family.

1150469:RSPPHO RS15835
gene id: 1150469:RSPPHO_RS15835
uniprot id: H6SQ70
names: Subcellular Location Annotation
messages: Membrane

1150469:RSPPHO RS07980
gene id: 1150469:RSPPHO_RS07980
uniprot id: H6SJF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Membrane
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

1150469:RSPPHO RS13525
gene id: 1150469:RSPPHO_RS13525
uniprot id: H6SMK9
names: Similarity
messages: Belongs to the Tim44 family.

1150469:RSPPHO RS01405
gene id: 1150469:RSPPHO_RS01405
uniprot id: H6SMY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1150469:RSPPHO RS10230
gene id: 1150469:RSPPHO_RS10230
uniprot id: H6SKM3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1150469:RSPPHO RS02910
gene id: 1150469:RSPPHO_RS02910
uniprot id: H6SP74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1150469:RSPPHO RS06955
gene id: 1150469:RSPPHO_RS06955
uniprot id: H6SSP1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1150469:RSPPHO RS02255
gene id: 1150469:RSPPHO_RS02255
uniprot id: H6SNV7
names: Similarity
messages: Belongs to the universal stress protein A family.

1150469:RSPPHO RS14385
gene id: 1150469:RSPPHO_RS14385
uniprot id: H6SNI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1150469:RSPPHO RS11390
gene id: 1150469:RSPPHO_RS11390
uniprot id: H6SL90
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1150469:RSPPHO RS14435
gene id: 1150469:RSPPHO_RS14435
uniprot id: H6SNJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1150469:RSPPHO RS05030
gene id: 1150469:RSPPHO_RS05030
uniprot id: H6SRL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1150469:RSPPHO RS17145
gene id: 1150469:RSPPHO_RS17145
uniprot id: H6SRA7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1150469:RSPPHO RS11015
gene id: 1150469:RSPPHO_RS11015
uniprot id: H6SL19
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1150469:RSPPHO RS05335
gene id: 1150469:RSPPHO_RS05335
uniprot id: H6SRS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1150469:RSPPHO RS17930
gene id: 1150469:RSPPHO_RS17930
uniprot id: H6SLD9
names: Similarity
messages: Belongs to the glutamate synthase family.

1150469:RSPPHO RS12110
gene id: 1150469:RSPPHO_RS12110
uniprot id: H6SLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1150469:RSPPHO RS06810
gene id: 1150469:RSPPHO_RS06810
uniprot id: H6SSL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1150469:RSPPHO RS07705
gene id: 1150469:RSPPHO_RS07705
uniprot id: H6SJA4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1150469:RSPPHO RS04890
gene id: 1150469:RSPPHO_RS04890
uniprot id: H6SRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1150469:RSPPHO RS10120
gene id: 1150469:RSPPHO_RS10120
uniprot id: H6SKK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1150469:RSPPHO RS08360
gene id: 1150469:RSPPHO_RS08360
uniprot id: H6SJM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1150469:RSPPHO RS07585
gene id: 1150469:RSPPHO_RS07585
uniprot id: H6SJ82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1150469:RSPPHO RS07370
gene id: 1150469:RSPPHO_RS07370
uniprot id: H6SJ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1150469:RSPPHO RS01355
gene id: 1150469:RSPPHO_RS01355
uniprot id: H6SMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1150469:RSPPHO RS10155
gene id: 1150469:RSPPHO_RS10155
uniprot id: H6SKK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1150469:RSPPHO RS14355
gene id: 1150469:RSPPHO_RS14355
uniprot id: H6SNH5
names: Subcellular Location Annotation
messages: Cell inner membrane