1145276:T479 RS17125
gene id: 1145276:T479_RS17125
uniprot id: A0A806LSE8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS17205
gene id: 1145276:T479_RS17205
uniprot id: A0A806LNP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1145276:T479 RS13375
gene id: 1145276:T479_RS13375
uniprot id: A0A806LTD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1145276:T479 RS13520
gene id: 1145276:T479_RS13520
uniprot id: A0A806LR45
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1145276:T479 RS06415
gene id: 1145276:T479_RS06415
uniprot id: A0A806LNP4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1145276:T479 RS12840
gene id: 1145276:T479_RS12840
uniprot id: A0A806LQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS19200
gene id: 1145276:T479_RS19200
uniprot id: A0A806LUZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS12695
gene id: 1145276:T479_RS12695
uniprot id: A0A806LSY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS17390
gene id: 1145276:T479_RS17390
uniprot id: A0A806LYI0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1145276:T479 RS02845
gene id: 1145276:T479_RS02845
uniprot id: A0A806LK83
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1145276:T479 RS16365
gene id: 1145276:T479_RS16365
uniprot id: A0A806LKZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1145276:T479 RS02075
gene id: 1145276:T479_RS02075
uniprot id: A0A806LDV7
names: Similarity
messages: Belongs to the ArsC family.

1145276:T479 RS17195
gene id: 1145276:T479_RS17195
uniprot id: A0A806LWV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1145276:T479 RS03805
gene id: 1145276:T479_RS03805
uniprot id: A0A806LFY2
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS00755
gene id: 1145276:T479_RS00755
uniprot id: A0A806LK16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1145276:T479 RS07185
gene id: 1145276:T479_RS07185
uniprot id: A0A806LGE3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1145276:T479 RS17895
gene id: 1145276:T479_RS17895
uniprot id: A0A806LLP9
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS00885
gene id: 1145276:T479_RS00885
uniprot id: A0A806LFW4
names: Similarity
messages: Belongs to the catalase family.

1145276:T479 RS18465
gene id: 1145276:T479_RS18465
uniprot id: A0A806LUL5
names: Similarity
messages: Belongs to the HPr family.

1145276:T479 RS06845
gene id: 1145276:T479_RS06845
uniprot id: A0A806LN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS17810
gene id: 1145276:T479_RS17810
uniprot id: A0A806LVI0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.

1145276:T479 RS04685
gene id: 1145276:T479_RS04685
uniprot id: A0A806LL87
names: Similarity
messages: Belongs to the DDAH family.

1145276:T479 RS03215
gene id: 1145276:T479_RS03215
uniprot id: A0A806LKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1145276:T479 RS02730
gene id: 1145276:T479_RS02730
uniprot id: A0A806LK57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1145276:T479 RS22650
gene id: 1145276:T479_RS22650
uniprot id: A0A806LV83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS13050
gene id: 1145276:T479_RS13050
uniprot id: A0A806LRV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS21575
gene id: 1145276:T479_RS21575
uniprot id: A0A806LQN1
names: Similarity
messages: Belongs to the peptidase C56 family.

1145276:T479 RS03690
gene id: 1145276:T479_RS03690
uniprot id: A0A806LH77
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS07135
gene id: 1145276:T479_RS07135
uniprot id: A0A806LGD7
names: Similarity
messages: Belongs to the SleB family.

1145276:T479 RS20990
gene id: 1145276:T479_RS20990
uniprot id: A0A806LUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS04100
gene id: 1145276:T479_RS04100
uniprot id: A0A806LHE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS17155
gene id: 1145276:T479_RS17155
uniprot id: A0A806LVA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS04270
gene id: 1145276:T479_RS04270
uniprot id: A0A806LL00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

1145276:T479 RS02385
gene id: 1145276:T479_RS02385
uniprot id: A0A806LKU9
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

1145276:T479 RS06775
gene id: 1145276:T479_RS06775
uniprot id: A0A806LGA6
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS21085
gene id: 1145276:T479_RS21085
uniprot id: A0A806LVX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1145276:T479 RS02735
gene id: 1145276:T479_RS02735
uniprot id: A0A806LFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1145276:T479 RS18500
gene id: 1145276:T479_RS18500
uniprot id: A0A806LVU2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1145276:T479 RS18715
gene id: 1145276:T479_RS18715
uniprot id: A0A806LND7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1145276:T479 RS21840
gene id: 1145276:T479_RS21840
uniprot id: A0A806LNI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1145276:T479 RS21030
gene id: 1145276:T479_RS21030
uniprot id: A0A806LQF0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS18805
gene id: 1145276:T479_RS18805
uniprot id: A0A806LX91
names: Similarity
messages: Belongs to the CdaR family.

1145276:T479 RS04420
gene id: 1145276:T479_RS04420
uniprot id: A0A806LMQ4
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS04310
gene id: 1145276:T479_RS04310
uniprot id: A0A806LEZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1145276:T479 RS21155
gene id: 1145276:T479_RS21155
uniprot id: A0A806LNB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metal hydrolase YfiT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Possible metal-dependent hydrolase.

1145276:T479 RS01890
gene id: 1145276:T479_RS01890
uniprot id: A0A806LDL3
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS14660
gene id: 1145276:T479_RS14660
uniprot id: A0A806LU59
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1145276:T479 RS13160
gene id: 1145276:T479_RS13160
uniprot id: A0A806LJC3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1145276:T479 RS10215
gene id: 1145276:T479_RS10215
uniprot id: A0A806LNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1145276:T479 RS15020
gene id: 1145276:T479_RS15020
uniprot id: A0A806LSY9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1145276:T479 RS17570
gene id: 1145276:T479_RS17570
uniprot id: A0A806LLI2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS08755
gene id: 1145276:T479_RS08755
uniprot id: A0A806LHA9
names: Function
names: Similarity
messages: Belongs to the LutB/YkgF family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate.

1145276:T479 RS13625
gene id: 1145276:T479_RS13625
uniprot id: A0A806LTJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS19495
gene id: 1145276:T479_RS19495
uniprot id: A0A806LMB8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1145276:T479 RS03125
gene id: 1145276:T479_RS03125
uniprot id: A0A806LGX8
names: Similarity
messages: Belongs to the bacterial flagellin family.

1145276:T479 RS04335
gene id: 1145276:T479_RS04335
uniprot id: A0A806LL03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1145276:T479 RS20525
gene id: 1145276:T479_RS20525
uniprot id: A0A806LU34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1145276:T479 RS08430
gene id: 1145276:T479_RS08430
uniprot id: A0A806LGW4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1145276:T479 RS12505
gene id: 1145276:T479_RS12505
uniprot id: A0A806LQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1145276:T479 RS15525
gene id: 1145276:T479_RS15525
uniprot id: A0A806LLY2
names: Similarity
messages: Belongs to the peptidase S14 family.

1145276:T479 RS16865
gene id: 1145276:T479_RS16865
uniprot id: A0A806LMI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1145276:T479 RS04505
gene id: 1145276:T479_RS04505
uniprot id: A0A806LLW3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS04355
gene id: 1145276:T479_RS04355
uniprot id: A0A806LNW5
names: Similarity
messages: Belongs to the UPF0749 family.

1145276:T479 RS18120
gene id: 1145276:T479_RS18120
uniprot id: A0A806LX89
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS21570
gene id: 1145276:T479_RS21570
uniprot id: A0A806LNF2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS02545
gene id: 1145276:T479_RS02545
uniprot id: A0A806LK19
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1145276:T479 RS02330
gene id: 1145276:T479_RS02330
uniprot id: A0A806LKT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1145276:T479 RS04600
gene id: 1145276:T479_RS04600
uniprot id: A0A806LF89
names: Similarity
messages: Belongs to the YicC/YloC family.

1145276:T479 RS08030
gene id: 1145276:T479_RS08030
uniprot id: A0A806LNL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1145276:T479 RS04315
gene id: 1145276:T479_RS04315
uniprot id: A0A806LHH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1145276:T479 RS22025
gene id: 1145276:T479_RS22025
uniprot id: A0A806LUW4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1145276:T479 RS05960
gene id: 1145276:T479_RS05960
uniprot id: A0A806LPQ6
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1145276:T479 RS04985
gene id: 1145276:T479_RS04985
uniprot id: A0A806LHW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1145276:T479 RS21435
gene id: 1145276:T479_RS21435
uniprot id: A0A806LUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS05425
gene id: 1145276:T479_RS05425
uniprot id: A0A806LLL9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS04350
gene id: 1145276:T479_RS04350
uniprot id: A0A806LLU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1145276:T479 RS09190
gene id: 1145276:T479_RS09190
uniprot id: A0A806LNG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS15340
gene id: 1145276:T479_RS15340
uniprot id: A0A806LRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS16895
gene id: 1145276:T479_RS16895
uniprot id: A0A806LL51
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1145276:T479 RS18025
gene id: 1145276:T479_RS18025
uniprot id: A0A806LVM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1145276:T479 RS09445
gene id: 1145276:T479_RS09445
uniprot id: A0A806LP97
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS05455
gene id: 1145276:T479_RS05455
uniprot id: A0A806LI49
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1145276:T479 RS12495
gene id: 1145276:T479_RS12495
uniprot id: A0A806LRM2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1145276:T479 RS05825
gene id: 1145276:T479_RS05825
uniprot id: A0A806LH72
names: Subcellular Location Annotation
messages: Cell membrane

1145276:T479 RS18900
gene id: 1145276:T479_RS18900
uniprot id: A0A806LM41
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1145276:T479 RS10980
gene id: 1145276:T479_RS10980
uniprot id: A0A806LTV3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS10165
gene id: 1145276:T479_RS10165
uniprot id: A0A806LNY5
names: Similarity
messages: Belongs to the HesB/IscA family.

1145276:T479 RS17105
gene id: 1145276:T479_RS17105
uniprot id: A0A806LX42
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS03275
gene id: 1145276:T479_RS03275
uniprot id: A0A806LL91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1145276:T479 RS06390
gene id: 1145276:T479_RS06390
uniprot id: A0A806LRE0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS17710
gene id: 1145276:T479_RS17710
uniprot id: A0A806LSK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1145276:T479 RS00170
gene id: 1145276:T479_RS00170
uniprot id: A0A806LE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1145276:T479 RS17515
gene id: 1145276:T479_RS17515
uniprot id: A0A806LWX8
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS21245
gene id: 1145276:T479_RS21245
uniprot id: A0A806LNA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCF family. ARE2 subfamily.
messages: Binds within the E-site of the 70S ribosome, where it contacts ribosomal proteins of the large and small subunit, the 16 and 23S rRNAs and the acceptor arm of the P-site tRNA.
messages: Cytoplasm
messages: Recognizes and binds in the vacant E-site of ribosomes stalled by some peptidyltransferase center (PTC)-targeting antibiotics. Makes contact with the PTC and both ribosomal subunits. Induces conformational changes in the P-site, which allows it to dislodge the antibiotic from its PTC binding site.
messages: The antibiotic resistance domain (ARD) is packed between the 23S rRNA and the acceptor arm of the P-site tRNA and inserts into the peptidyltransferase center (PTC). The C-terminal extension (CTE) contacts the small ribosomal subunit, positioned in the Shine-Dalgarno-anti-Shine-Dalgarno cavity.

1145276:T479 RS16830
gene id: 1145276:T479_RS16830
uniprot id: A0A806LWN1
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1145276:T479 RS07580
gene id: 1145276:T479_RS07580
uniprot id: A0A806LI12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1145276:T479 RS13425
gene id: 1145276:T479_RS13425
uniprot id: A0A806LTE2
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS02560
gene id: 1145276:T479_RS02560
uniprot id: A0A806LKY0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS19995
gene id: 1145276:T479_RS19995
uniprot id: A0A806LUA2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1145276:T479 RS16815
gene id: 1145276:T479_RS16815
uniprot id: A0A806LMH2
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1145276:T479 RS04860
gene id: 1145276:T479_RS04860
uniprot id: A0A806LFE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1145276:T479 RS04760
gene id: 1145276:T479_RS04760
uniprot id: A0A806LQJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1145276:T479 RS07445
gene id: 1145276:T479_RS07445
uniprot id: A0A806LP75
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS17855
gene id: 1145276:T479_RS17855
uniprot id: A0A806LT94
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1145276:T479 RS03230
gene id: 1145276:T479_RS03230
uniprot id: A0A806LL80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1145276:T479 RS09615
gene id: 1145276:T479_RS09615
uniprot id: A0A806LPC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

1145276:T479 RS05110
gene id: 1145276:T479_RS05110
uniprot id: A0A806LLF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1145276:T479 RS14540
gene id: 1145276:T479_RS14540
uniprot id: A0A806LQZ9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1145276:T479 RS01690
gene id: 1145276:T479_RS01690
uniprot id: A0A806LET8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

1145276:T479 RS14135
gene id: 1145276:T479_RS14135
uniprot id: A0A806LVC1
names: Similarity
messages: Belongs to the transpeptidase family.

1145276:T479 RS18585
gene id: 1145276:T479_RS18585
uniprot id: A0A806LM09
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS07590
gene id: 1145276:T479_RS07590
uniprot id: A0A806LS11
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS09260
gene id: 1145276:T479_RS09260
uniprot id: A0A806LP68
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS19550
gene id: 1145276:T479_RS19550
uniprot id: A0A806LWA8
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS07895
gene id: 1145276:T479_RS07895
uniprot id: A0A806LW27
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS16430
gene id: 1145276:T479_RS16430
uniprot id: A0A806LUW7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1145276:T479 RS00505
gene id: 1145276:T479_RS00505
uniprot id: A0A806LEA2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1145276:T479 RS17170
gene id: 1145276:T479_RS17170
uniprot id: A0A806LU32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1145276:T479 RS07305
gene id: 1145276:T479_RS07305
uniprot id: A0A806LHU8
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS00345
gene id: 1145276:T479_RS00345
uniprot id: A0A806LIY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1145276:T479 RS12195
gene id: 1145276:T479_RS12195
uniprot id: A0A806LSQ4
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

1145276:T479 RS19905
gene id: 1145276:T479_RS19905
uniprot id: A0A806LMK1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1145276:T479 RS04835
gene id: 1145276:T479_RS04835
uniprot id: A0A806LHT6
names: Similarity
messages: Belongs to the DprA/Smf family.

1145276:T479 RS13645
gene id: 1145276:T479_RS13645
uniprot id: A0A806LS82
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1145276:T479 RS17225
gene id: 1145276:T479_RS17225
uniprot id: A0A806LSE1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS16425
gene id: 1145276:T479_RS16425
uniprot id: A0A806LSK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1145276:T479 RS06725
gene id: 1145276:T479_RS06725
uniprot id: A0A806LG97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1145276:T479 RS00460
gene id: 1145276:T479_RS00460
uniprot id: A0A806LJ01
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1145276:T479 RS18545
gene id: 1145276:T479_RS18545
uniprot id: A0A806LTL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1145276:T479 RS12760
gene id: 1145276:T479_RS12760
uniprot id: A0A806LUJ2
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS10645
gene id: 1145276:T479_RS10645
uniprot id: A0A806LPU0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS15620
gene id: 1145276:T479_RS15620
uniprot id: A0A806LUL0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS18360
gene id: 1145276:T479_RS18360
uniprot id: A0A806LP31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS04770
gene id: 1145276:T479_RS04770
uniprot id: A0A806LP47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1145276:T479 RS04810
gene id: 1145276:T479_RS04810
uniprot id: A0A806LFD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1145276:T479 RS21855
gene id: 1145276:T479_RS21855
uniprot id: A0A806LSC7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1145276:T479 RS04930
gene id: 1145276:T479_RS04930
uniprot id: A0A806LFC8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1145276:T479 RS18515
gene id: 1145276:T479_RS18515
uniprot id: A0A806LUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1145276:T479 RS20490
gene id: 1145276:T479_RS20490
uniprot id: A0A806LUI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1145276:T479 RS05200
gene id: 1145276:T479_RS05200
uniprot id: A0A806LLI8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS17620
gene id: 1145276:T479_RS17620
uniprot id: A0A806LLJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1145276:T479 RS06585
gene id: 1145276:T479_RS06585
uniprot id: A0A806LG74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1145276:T479 RS12810
gene id: 1145276:T479_RS12810
uniprot id: A0A806LUK7
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS22655
gene id: 1145276:T479_RS22655
uniprot id: A0A806LP10
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS18875
gene id: 1145276:T479_RS18875
uniprot id: A0A806LT86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AfsR/DnrI/RedD regulatory family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS17615
gene id: 1145276:T479_RS17615
uniprot id: A0A806LSH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS19625
gene id: 1145276:T479_RS19625
uniprot id: A0A806LMI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1145276:T479 RS07385
gene id: 1145276:T479_RS07385
uniprot id: A0A806LGF2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1145276:T479 RS01185
gene id: 1145276:T479_RS01185
uniprot id: A0A806LDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS13095
gene id: 1145276:T479_RS13095
uniprot id: A0A806LRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1145276:T479 RS15185
gene id: 1145276:T479_RS15185
uniprot id: A0A806LRD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1145276:T479 RS01720
gene id: 1145276:T479_RS01720
uniprot id: A0A806LKH0
names: Similarity
messages: Belongs to the YjdM family.

1145276:T479 RS19390
gene id: 1145276:T479_RS19390
uniprot id: A0A806LTZ4
names: Similarity
messages: Belongs to the TelA family.

1145276:T479 RS16905
gene id: 1145276:T479_RS16905
uniprot id: A0A806LTY5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1145276:T479 RS12770
gene id: 1145276:T479_RS12770
uniprot id: A0A806LSZ6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1145276:T479 RS19435
gene id: 1145276:T479_RS19435
uniprot id: A0A806LY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS09015
gene id: 1145276:T479_RS09015
uniprot id: A0A806LIS2
names: Similarity
messages: Belongs to the peptidase C40 family.

1145276:T479 RS13260
gene id: 1145276:T479_RS13260
uniprot id: A0A806LQA6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1145276:T479 RS13755
gene id: 1145276:T479_RS13755
uniprot id: A0A806LSA5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the octanoyltransferase LipM family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. The reaction proceeds via an octanoyl-thioester enzyme intermediate.
messages: Monomer.

1145276:T479 RS15215
gene id: 1145276:T479_RS15215
uniprot id: A0A806LKC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS14960
gene id: 1145276:T479_RS14960
uniprot id: A0A806LK68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

1145276:T479 RS04840
gene id: 1145276:T479_RS04840
uniprot id: A0A806LMY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1145276:T479 RS21970
gene id: 1145276:T479_RS21970
uniprot id: A0A806LPZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1145276:T479 RS15280
gene id: 1145276:T479_RS15280
uniprot id: A0A806LMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS08555
gene id: 1145276:T479_RS08555
uniprot id: A0A806LJN6
names: Similarity
messages: Belongs to the peptidase S58 family.

1145276:T479 RS13315
gene id: 1145276:T479_RS13315
uniprot id: A0A806LJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1145276:T479 RS06205
gene id: 1145276:T479_RS06205
uniprot id: A0A806LG24
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1145276:T479 RS21405
gene id: 1145276:T479_RS21405
uniprot id: A0A806LQW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS16345
gene id: 1145276:T479_RS16345
uniprot id: A0A806LTL1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1145276:T479 RS19370
gene id: 1145276:T479_RS19370
uniprot id: A0A806LNN2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1145276:T479 RS16935
gene id: 1145276:T479_RS16935
uniprot id: A0A806LSW4
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1145276:T479 RS12470
gene id: 1145276:T479_RS12470
uniprot id: A0A806LRK0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS07415
gene id: 1145276:T479_RS07415
uniprot id: A0A806LGP4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1145276:T479 RS15220
gene id: 1145276:T479_RS15220
uniprot id: A0A806LMR8
names: Similarity
messages: Belongs to the RecJ family.

1145276:T479 RS04540
gene id: 1145276:T479_RS04540
uniprot id: A0A806LGF8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS13525
gene id: 1145276:T479_RS13525
uniprot id: A0A806LTH1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1145276:T479 RS06395
gene id: 1145276:T479_RS06395
uniprot id: A0A806LMT4
names: Similarity
messages: Belongs to the sigma-54 factor family.

1145276:T479 RS19815
gene id: 1145276:T479_RS19815
uniprot id: A0A806LV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS17980
gene id: 1145276:T479_RS17980
uniprot id: A0A806LNY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1145276:T479 RS07615
gene id: 1145276:T479_RS07615
uniprot id: A0A806LPA0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS05145
gene id: 1145276:T479_RS05145
uniprot id: A0A806LN50
names: Similarity
messages: Belongs to the ribF family.

1145276:T479 RS06285
gene id: 1145276:T479_RS06285
uniprot id: A0A806LPV3
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS22270
gene id: 1145276:T479_RS22270
uniprot id: A0A806LWI1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS19980
gene id: 1145276:T479_RS19980
uniprot id: A0A806LTU0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1145276:T479 RS04970
gene id: 1145276:T479_RS04970
uniprot id: A0A806LM53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1145276:T479 RS05745
gene id: 1145276:T479_RS05745
uniprot id: A0A806LI95
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS21890
gene id: 1145276:T479_RS21890
uniprot id: A0A806LXJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1145276:T479 RS06455
gene id: 1145276:T479_RS06455
uniprot id: A0A806LG53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS08550
gene id: 1145276:T479_RS08550
uniprot id: A0A806LGY6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS19810
gene id: 1145276:T479_RS19810
uniprot id: A0A806LPS8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1145276:T479 RS05045
gene id: 1145276:T479_RS05045
uniprot id: A0A806LLF5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1145276:T479 RS20830
gene id: 1145276:T479_RS20830
uniprot id: A0A806LVS7
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS00535
gene id: 1145276:T479_RS00535
uniprot id: A0A806LND8
names: Cofactor
messages: Can also use Mn(2+) ion.

1145276:T479 RS18765
gene id: 1145276:T479_RS18765
uniprot id: A0A806LNF1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1145276:T479 RS03025
gene id: 1145276:T479_RS03025
uniprot id: A0A806LGV7
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS15915
gene id: 1145276:T479_RS15915
uniprot id: A0A806LW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS11445
gene id: 1145276:T479_RS11445
uniprot id: A0A806LKY1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS21865
gene id: 1145276:T479_RS21865
uniprot id: A0A806LPX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1145276:T479 RS22405
gene id: 1145276:T479_RS22405
uniprot id: A0A806LVF0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS21850
gene id: 1145276:T479_RS21850
uniprot id: A0A806LW96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1145276:T479 RS15765
gene id: 1145276:T479_RS15765
uniprot id: A0A806LUN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1145276:T479 RS00895
gene id: 1145276:T479_RS00895
uniprot id: A0A806LJ76
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1145276:T479 RS05580
gene id: 1145276:T479_RS05580
uniprot id: A0A806LND3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1145276:T479 RS06410
gene id: 1145276:T479_RS06410
uniprot id: A0A806LIJ9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS00005
gene id: 1145276:T479_RS00005
uniprot id: A0A806LJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1145276:T479 RS03335
gene id: 1145276:T479_RS03335
uniprot id: A0A806LEF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1145276:T479 RS16960
gene id: 1145276:T479_RS16960
uniprot id: A0A806LSB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1145276:T479 RS16370
gene id: 1145276:T479_RS16370
uniprot id: A0A806LWE4
names: Similarity
messages: Belongs to the thioredoxin family.

1145276:T479 RS09515
gene id: 1145276:T479_RS09515
uniprot id: A0A806LQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS19450
gene id: 1145276:T479_RS19450
uniprot id: A0A806LMA7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS16780
gene id: 1145276:T479_RS16780
uniprot id: A0A806LWM0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1145276:T479 RS00750
gene id: 1145276:T479_RS00750
uniprot id: A0A806LNI4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1145276:T479 RS10635
gene id: 1145276:T479_RS10635
uniprot id: A0A806LI66
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1145276:T479 RS22460
gene id: 1145276:T479_RS22460
uniprot id: A0A806LNW6
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04965
gene id: 1145276:T479_RS04965
uniprot id: A0A806LQM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1145276:T479 RS05430
gene id: 1145276:T479_RS05430
uniprot id: A0A806LFQ6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1145276:T479 RS12540
gene id: 1145276:T479_RS12540
uniprot id: A0A806LKA5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1145276:T479 RS04365
gene id: 1145276:T479_RS04365
uniprot id: A0A806LHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1145276:T479 RS18815
gene id: 1145276:T479_RS18815
uniprot id: A0A806LT71
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1145276:T479 RS16665
gene id: 1145276:T479_RS16665
uniprot id: A0A806LME4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1145276:T479 RS13995
gene id: 1145276:T479_RS13995
uniprot id: A0A806LM46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS12480
gene id: 1145276:T479_RS12480
uniprot id: A0A806LK93
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1145276:T479 RS00150
gene id: 1145276:T479_RS00150
uniprot id: A0A806LFJ6
names: Similarity
messages: Belongs to the DCK/DGK family.

1145276:T479 RS22030
gene id: 1145276:T479_RS22030
uniprot id: A0A806LNP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS15630
gene id: 1145276:T479_RS15630
uniprot id: A0A806LKJ6
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

1145276:T479 RS20095
gene id: 1145276:T479_RS20095
uniprot id: A0A806LP27
names: Similarity
messages: Belongs to the P(II) protein family.

1145276:T479 RS13275
gene id: 1145276:T479_RS13275
uniprot id: A0A806LQZ6
names: Similarity
messages: Belongs to the CobH/CbiC family.

1145276:T479 RS18860
gene id: 1145276:T479_RS18860
uniprot id: A0A806LUT8
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS03395
gene id: 1145276:T479_RS03395
uniprot id: A0A806LM45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1145276:T479 RS14820
gene id: 1145276:T479_RS14820
uniprot id: A0A806LR53
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1145276:T479 RS10880
gene id: 1145276:T479_RS10880
uniprot id: A0A806LI73
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS20115
gene id: 1145276:T479_RS20115
uniprot id: A0A806LUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1145276:T479 RS12235
gene id: 1145276:T479_RS12235
uniprot id: A0A806LK49
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1145276:T479 RS13600
gene id: 1145276:T479_RS13600
uniprot id: A0A806LKW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1145276:T479 RS10315
gene id: 1145276:T479_RS10315
uniprot id: A0A806LRY4
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS22125
gene id: 1145276:T479_RS22125
uniprot id: A0A806LQ18
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1145276:T479 RS17185
gene id: 1145276:T479_RS17185
uniprot id: A0A806LSC8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1145276:T479 RS10785
gene id: 1145276:T479_RS10785
uniprot id: A0A806LQT7
names: Similarity
messages: Belongs to the peptidase S66 family.

1145276:T479 RS13575
gene id: 1145276:T479_RS13575
uniprot id: A0A806LTI5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1145276:T479 RS13305
gene id: 1145276:T479_RS13305
uniprot id: A0A806LKQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1145276:T479 RS01175
gene id: 1145276:T479_RS01175
uniprot id: A0A806LJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1145276:T479 RS05155
gene id: 1145276:T479_RS05155
uniprot id: A0A806LGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1145276:T479 RS07215
gene id: 1145276:T479_RS07215
uniprot id: A0A806LGK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1145276:T479 RS16845
gene id: 1145276:T479_RS16845
uniprot id: A0A806LL41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1145276:T479 RS05495
gene id: 1145276:T479_RS05495
uniprot id: A0A806LMF5
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS14485
gene id: 1145276:T479_RS14485
uniprot id: A0A806LLD1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1145276:T479 RS13605
gene id: 1145276:T479_RS13605
uniprot id: A0A806LQI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1145276:T479 RS22200
gene id: 1145276:T479_RS22200
uniprot id: A0A806LVA6
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS19645
gene id: 1145276:T479_RS19645
uniprot id: A0A806LMF0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1145276:T479 RS02985
gene id: 1145276:T479_RS02985
uniprot id: A0A806LK87
names: Similarity
messages: Belongs to the peptidase C40 family.

1145276:T479 RS22395
gene id: 1145276:T479_RS22395
uniprot id: A0A806LNV8
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS17545
gene id: 1145276:T479_RS17545
uniprot id: A0A806LU64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1145276:T479 RS04865
gene id: 1145276:T479_RS04865
uniprot id: A0A806LQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

1145276:T479 RS21770
gene id: 1145276:T479_RS21770
uniprot id: A0A806LNJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1145276:T479 RS08210
gene id: 1145276:T479_RS08210
uniprot id: A0A806LID1
names: Similarity
messages: Belongs to the peptidase C40 family.

1145276:T479 RS00230
gene id: 1145276:T479_RS00230
uniprot id: A0A806LKL4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1145276:T479 RS20585
gene id: 1145276:T479_RS20585
uniprot id: A0A806LYM1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1145276:T479 RS15235
gene id: 1145276:T479_RS15235
uniprot id: A0A806LLS4
names: Similarity
messages: Belongs to the TrpF family.

1145276:T479 RS15375
gene id: 1145276:T479_RS15375
uniprot id: A0A806LKG0
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1145276:T479 RS06320
gene id: 1145276:T479_RS06320
uniprot id: A0A806LG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS05205
gene id: 1145276:T479_RS05205
uniprot id: A0A806LGW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1145276:T479 RS19990
gene id: 1145276:T479_RS19990
uniprot id: A0A806LYC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1145276:T479 RS04450
gene id: 1145276:T479_RS04450
uniprot id: A0A806LLV6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1145276:T479 RS16075
gene id: 1145276:T479_RS16075
uniprot id: A0A806LSH0
names: Similarity
messages: Belongs to the peptidase S8 family.

1145276:T479 RS19955
gene id: 1145276:T479_RS19955
uniprot id: A0A806LML0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1145276:T479 RS19430
gene id: 1145276:T479_RS19430
uniprot id: A0A806LME5
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1145276:T479 RS04295
gene id: 1145276:T479_RS04295
uniprot id: A0A806LLT3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1145276:T479 RS20035
gene id: 1145276:T479_RS20035
uniprot id: A0A806LVE2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1145276:T479 RS18055
gene id: 1145276:T479_RS18055
uniprot id: A0A806LSS3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1145276:T479 RS18370
gene id: 1145276:T479_RS18370
uniprot id: A0A806LSX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1145276:T479 RS04550
gene id: 1145276:T479_RS04550
uniprot id: A0A806LF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS20845
gene id: 1145276:T479_RS20845
uniprot id: A0A806LU99
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS02515
gene id: 1145276:T479_RS02515
uniprot id: A0A806LMW2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS10405
gene id: 1145276:T479_RS10405
uniprot id: A0A806LI23
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1145276:T479 RS18625
gene id: 1145276:T479_RS18625
uniprot id: A0A806LT26
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS14420
gene id: 1145276:T479_RS14420
uniprot id: A0A806LQY0
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1145276:T479 RS04855
gene id: 1145276:T479_RS04855
uniprot id: A0A806LLA0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1145276:T479 RS01060
gene id: 1145276:T479_RS01060
uniprot id: A0A806LKZ2
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS13355
gene id: 1145276:T479_RS13355
uniprot id: A0A806LKR4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS21995
gene id: 1145276:T479_RS21995
uniprot id: A0A806LXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1145276:T479 RS14670
gene id: 1145276:T479_RS14670
uniprot id: A0A806LMI3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1145276:T479 RS00375
gene id: 1145276:T479_RS00375
uniprot id: A0A806LFN3
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS17235
gene id: 1145276:T479_RS17235
uniprot id: A0A806LWW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1145276:T479 RS16060
gene id: 1145276:T479_RS16060
uniprot id: A0A806LRU8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS12950
gene id: 1145276:T479_RS12950
uniprot id: A0A806LKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS00735
gene id: 1145276:T479_RS00735
uniprot id: A0A806LEE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS17990
gene id: 1145276:T479_RS17990
uniprot id: A0A806LUD8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS17905
gene id: 1145276:T479_RS17905
uniprot id: A0A806LTA9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS08140
gene id: 1145276:T479_RS08140
uniprot id: A0A806LGR9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS03905
gene id: 1145276:T479_RS03905
uniprot id: A0A806LG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS15450
gene id: 1145276:T479_RS15450
uniprot id: A0A806LLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

1145276:T479 RS03400
gene id: 1145276:T479_RS03400
uniprot id: A0A806LKI3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1145276:T479 RS15360
gene id: 1145276:T479_RS15360
uniprot id: A0A806LW05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1145276:T479 RS03140
gene id: 1145276:T479_RS03140
uniprot id: A0A806LFK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1145276:T479 RS22665
gene id: 1145276:T479_RS22665
uniprot id: A0A806LVJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1145276:T479 RS03035
gene id: 1145276:T479_RS03035
uniprot id: A0A806LKA3
names: Similarity
messages: Belongs to the peptidase S41A family.

1145276:T479 RS12775
gene id: 1145276:T479_RS12775
uniprot id: A0A806LIZ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1145276:T479 RS00470
gene id: 1145276:T479_RS00470
uniprot id: A0A806LNC8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1145276:T479 RS17635
gene id: 1145276:T479_RS17635
uniprot id: A0A806LVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS21700
gene id: 1145276:T479_RS21700
uniprot id: A0A806LUP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS16405
gene id: 1145276:T479_RS16405
uniprot id: A0A806LM96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1145276:T479 RS21800
gene id: 1145276:T479_RS21800
uniprot id: A0A806LW86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1145276:T479 RS13650
gene id: 1145276:T479_RS13650
uniprot id: A0A806LQI9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1145276:T479 RS22725
gene id: 1145276:T479_RS22725
uniprot id: A0A806LPB3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1145276:T479 RS13780
gene id: 1145276:T479_RS13780
uniprot id: A0A806LQL1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1145276:T479 RS14380
gene id: 1145276:T479_RS14380
uniprot id: A0A806LK21
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS20540
gene id: 1145276:T479_RS20540
uniprot id: A0A806LUJ5
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS02160
gene id: 1145276:T479_RS02160
uniprot id: A0A806LF32
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1145276:T479 RS10615
gene id: 1145276:T479_RS10615
uniprot id: A0A806LQQ1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS16820
gene id: 1145276:T479_RS16820
uniprot id: A0A806LS60
names: Similarity
messages: Belongs to the ThiD family.

1145276:T479 RS05225
gene id: 1145276:T479_RS05225
uniprot id: A0A806LMA3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1145276:T479 RS03965
gene id: 1145276:T479_RS03965
uniprot id: A0A806LEW6
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1145276:T479 RS13455
gene id: 1145276:T479_RS13455
uniprot id: A0A806LQE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS15350
gene id: 1145276:T479_RS15350
uniprot id: A0A806LRH1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1145276:T479 RS03055
gene id: 1145276:T479_RS03055
uniprot id: A0A806LPM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1145276:T479 RS07130
gene id: 1145276:T479_RS07130
uniprot id: A0A806LQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

1145276:T479 RS14120
gene id: 1145276:T479_RS14120
uniprot id: A0A806LL66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1145276:T479 RS17550
gene id: 1145276:T479_RS17550
uniprot id: A0A806LSJ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

1145276:T479 RS03145
gene id: 1145276:T479_RS03145
uniprot id: A0A806LKC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1145276:T479 RS04000
gene id: 1145276:T479_RS04000
uniprot id: A0A806LHC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1145276:T479 RS08945
gene id: 1145276:T479_RS08945
uniprot id: A0A806LJV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS01250
gene id: 1145276:T479_RS01250
uniprot id: A0A806LNQ6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS11160
gene id: 1145276:T479_RS11160
uniprot id: A0A806LIF4
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS00330
gene id: 1145276:T479_RS00330
uniprot id: A0A806LKN4
names: Similarity
messages: Belongs to the RutC family.

1145276:T479 RS13105
gene id: 1145276:T479_RS13105
uniprot id: A0A806LKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1145276:T479 RS22645
gene id: 1145276:T479_RS22645
uniprot id: A0A806LQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1145276:T479 RS21735
gene id: 1145276:T479_RS21735
uniprot id: A0A806LXE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1145276:T479 RS04475
gene id: 1145276:T479_RS04475
uniprot id: A0A806LMR2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1145276:T479 RS14515
gene id: 1145276:T479_RS14515
uniprot id: A0A806LJY9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1145276:T479 RS03585
gene id: 1145276:T479_RS03585
uniprot id: A0A806LH60
names: Similarity
messages: Belongs to the UPF0312 family.

1145276:T479 RS04170
gene id: 1145276:T479_RS04170
uniprot id: A0A806LKX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS07230
gene id: 1145276:T479_RS07230
uniprot id: A0A806LQA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1145276:T479 RS07965
gene id: 1145276:T479_RS07965
uniprot id: A0A806LS83
names: Similarity
messages: Belongs to the EutP/PduV family.

1145276:T479 RS14980
gene id: 1145276:T479_RS14980
uniprot id: A0A806LLM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1145276:T479 RS03555
gene id: 1145276:T479_RS03555
uniprot id: A0A806LKK4
names: Subcellular Location Annotation
messages: cell wall

1145276:T479 RS02745
gene id: 1145276:T479_RS02745
uniprot id: A0A806LE99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS00325
gene id: 1145276:T479_RS00325
uniprot id: A0A806LFM3
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1145276:T479 RS01330
gene id: 1145276:T479_RS01330
uniprot id: A0A806LL42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS19735
gene id: 1145276:T479_RS19735
uniprot id: A0A806LMK2
names: Similarity
messages: Belongs to the UPF0229 family.

1145276:T479 RS18440
gene id: 1145276:T479_RS18440
uniprot id: A0A806LTJ1
names: Subcellular Location Annotation
messages: Cell membrane

1145276:T479 RS04165
gene id: 1145276:T479_RS04165
uniprot id: A0A806LG59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1145276:T479 RS22220
gene id: 1145276:T479_RS22220
uniprot id: A0A806LWH1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS02430
gene id: 1145276:T479_RS02430
uniprot id: A0A806LE39
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1145276:T479 RS17020
gene id: 1145276:T479_RS17020
uniprot id: A0A806LML1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1145276:T479 RS04670
gene id: 1145276:T479_RS04670
uniprot id: A0A806LF72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1145276:T479 RS15005
gene id: 1145276:T479_RS15005
uniprot id: A0A806LUB4
names: Similarity
messages: Belongs to the UPF0473 family.

1145276:T479 RS15390
gene id: 1145276:T479_RS15390
uniprot id: A0A806LRK4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1145276:T479 RS02255
gene id: 1145276:T479_RS02255
uniprot id: A0A806LF52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1145276:T479 RS20785
gene id: 1145276:T479_RS20785
uniprot id: A0A806LPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS04565
gene id: 1145276:T479_RS04565
uniprot id: A0A806LP08
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS14810
gene id: 1145276:T479_RS14810
uniprot id: A0A806LSV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1145276:T479 RS22305
gene id: 1145276:T479_RS22305
uniprot id: A0A806LXV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1145276:T479 RS14170
gene id: 1145276:T479_RS14170
uniprot id: A0A806LL74
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1145276:T479 RS21795
gene id: 1145276:T479_RS21795
uniprot id: A0A806LQR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1145276:T479 RS20590
gene id: 1145276:T479_RS20590
uniprot id: A0A806LUK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS16685
gene id: 1145276:T479_RS16685
uniprot id: A0A806LSR0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS08570
gene id: 1145276:T479_RS08570
uniprot id: A0A806LII6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS03445
gene id: 1145276:T479_RS03445
uniprot id: A0A806LM57
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1145276:T479 RS15240
gene id: 1145276:T479_RS15240
uniprot id: A0A806LRE7
names: Similarity
messages: Belongs to the TrpC family.

1145276:T479 RS00110
gene id: 1145276:T479_RS00110
uniprot id: A0A806LIS1
names: Similarity
messages: Belongs to the peptidase S8 family.

1145276:T479 RS01795
gene id: 1145276:T479_RS01795
uniprot id: A0A806LGA5
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS03065
gene id: 1145276:T479_RS03065
uniprot id: A0A806LN59
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1145276:T479 RS08195
gene id: 1145276:T479_RS08195
uniprot id: A0A806LJG9
names: Similarity
messages: Belongs to the peptidase C56 family.

1145276:T479 RS00565
gene id: 1145276:T479_RS00565
uniprot id: A0A806LJ06
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS09235
gene id: 1145276:T479_RS09235
uniprot id: A0A806LNK0
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS07125
gene id: 1145276:T479_RS07125
uniprot id: A0A806LN49
names: Similarity
messages: Belongs to the asparaginase 1 family.

1145276:T479 RS12465
gene id: 1145276:T479_RS12465
uniprot id: A0A806LLA5
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS01190
gene id: 1145276:T479_RS01190
uniprot id: A0A806LNP7
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS09605
gene id: 1145276:T479_RS09605
uniprot id: A0A806LHQ4
names: Similarity
messages: Belongs to the peptidase S11 family.

1145276:T479 RS03165
gene id: 1145276:T479_RS03165
uniprot id: A0A806LEF4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1145276:T479 RS10170
gene id: 1145276:T479_RS10170
uniprot id: A0A806LJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1145276:T479 RS08105
gene id: 1145276:T479_RS08105
uniprot id: A0A806LIB5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1145276:T479 RS14590
gene id: 1145276:T479_RS14590
uniprot id: A0A806LR09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1145276:T479 RS17030
gene id: 1145276:T479_RS17030
uniprot id: A0A806LLC7
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1145276:T479 RS22155
gene id: 1145276:T479_RS22155
uniprot id: A0A806LNQ1
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04990
gene id: 1145276:T479_RS04990
uniprot id: A0A806LN20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1145276:T479 RS09625
gene id: 1145276:T479_RS09625
uniprot id: A0A806LHI6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS14395
gene id: 1145276:T479_RS14395
uniprot id: A0A806LU00
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS08990
gene id: 1145276:T479_RS08990
uniprot id: A0A806LR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS05885
gene id: 1145276:T479_RS05885
uniprot id: A0A806LFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1145276:T479 RS19875
gene id: 1145276:T479_RS19875
uniprot id: A0A806LNY6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1145276:T479 RS07530
gene id: 1145276:T479_RS07530
uniprot id: A0A806LML5
names: Similarity
messages: Belongs to the HupF/HypC family.

1145276:T479 RS21785
gene id: 1145276:T479_RS21785
uniprot id: A0A806LXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1145276:T479 RS15160
gene id: 1145276:T479_RS15160
uniprot id: A0A806LKB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS04155
gene id: 1145276:T479_RS04155
uniprot id: A0A806LMK4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1145276:T479 RS00075
gene id: 1145276:T479_RS00075
uniprot id: A0A806LCU3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1145276:T479 RS15265
gene id: 1145276:T479_RS15265
uniprot id: A0A806LS39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1145276:T479 RS18365
gene id: 1145276:T479_RS18365
uniprot id: A0A806LUJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1145276:T479 RS15130
gene id: 1145276:T479_RS15130
uniprot id: A0A806LLQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1145276:T479 RS04010
gene id: 1145276:T479_RS04010
uniprot id: A0A806LKV0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1145276:T479 RS18975
gene id: 1145276:T479_RS18975
uniprot id: A0A806LM91
names: Similarity
messages: Belongs to the peptidase S8 family.

1145276:T479 RS02580
gene id: 1145276:T479_RS02580
uniprot id: A0A806LK28
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1145276:T479 RS12885
gene id: 1145276:T479_RS12885
uniprot id: A0A806LRT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS05280
gene id: 1145276:T479_RS05280
uniprot id: A0A806LPF2
names: Similarity
messages: Belongs to the CinA family.

1145276:T479 RS02615
gene id: 1145276:T479_RS02615
uniprot id: A0A806LE23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS14885
gene id: 1145276:T479_RS14885
uniprot id: A0A806LR63
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1145276:T479 RS22610
gene id: 1145276:T479_RS22610
uniprot id: A0A806LVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1145276:T479 RS21905
gene id: 1145276:T479_RS21905
uniprot id: A0A806LQT2
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04880
gene id: 1145276:T479_RS04880
uniprot id: A0A806LFB6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1145276:T479 RS16735
gene id: 1145276:T479_RS16735
uniprot id: A0A806LSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1145276:T479 RS19425
gene id: 1145276:T479_RS19425
uniprot id: A0A806LTG1
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1145276:T479 RS00875
gene id: 1145276:T479_RS00875
uniprot id: A0A806LM37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1145276:T479 RS17880
gene id: 1145276:T479_RS17880
uniprot id: A0A806LSQ1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1145276:T479 RS00095
gene id: 1145276:T479_RS00095
uniprot id: A0A806LCQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1145276:T479 RS12645
gene id: 1145276:T479_RS12645
uniprot id: A0A806LLD0
names: Similarity
messages: Belongs to the UPF0145 family.

1145276:T479 RS21825
gene id: 1145276:T479_RS21825
uniprot id: A0A806LZB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1145276:T479 RS07355
gene id: 1145276:T479_RS07355
uniprot id: A0A806LHV9
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS07285
gene id: 1145276:T479_RS07285
uniprot id: A0A806LGE9
names: Similarity
messages: Belongs to the UPF0302 family.

1145276:T479 RS14340
gene id: 1145276:T479_RS14340
uniprot id: A0A806LVG1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1145276:T479 RS07375
gene id: 1145276:T479_RS07375
uniprot id: A0A806LN93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1145276:T479 RS06600
gene id: 1145276:T479_RS06600
uniprot id: A0A806LM76
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS09935
gene id: 1145276:T479_RS09935
uniprot id: A0A806LT88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

1145276:T479 RS21110
gene id: 1145276:T479_RS21110
uniprot id: A0A806LYX3
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS08150
gene id: 1145276:T479_RS08150
uniprot id: A0A806LPK5
names: Subcellular Location Annotation
messages: Cell membrane

1145276:T479 RS13220
gene id: 1145276:T479_RS13220
uniprot id: A0A806LUU1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1145276:T479 RS02625
gene id: 1145276:T479_RS02625
uniprot id: A0A806LLR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1145276:T479 RS14260
gene id: 1145276:T479_RS14260
uniprot id: A0A806LQV4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS01975
gene id: 1145276:T479_RS01975
uniprot id: A0A806LKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1145276:T479 RS16650
gene id: 1145276:T479_RS16650
uniprot id: A0A806LTT6
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1145276:T479 RS02550
gene id: 1145276:T479_RS02550
uniprot id: A0A806LE58
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1145276:T479 RS14650
gene id: 1145276:T479_RS14650
uniprot id: A0A806LVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1145276:T479 RS03565
gene id: 1145276:T479_RS03565
uniprot id: A0A806LPX7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 8 family.

1145276:T479 RS17645
gene id: 1145276:T479_RS17645
uniprot id: A0A806LNS9
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1145276:T479 RS03135
gene id: 1145276:T479_RS03135
uniprot id: A0A806LKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1145276:T479 RS07330
gene id: 1145276:T479_RS07330
uniprot id: A0A806LQC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1145276:T479 RS22595
gene id: 1145276:T479_RS22595
uniprot id: A0A806LV80
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS16900
gene id: 1145276:T479_RS16900
uniprot id: A0A806LNH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1145276:T479 RS10490
gene id: 1145276:T479_RS10490
uniprot id: A0A806M0U4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS01900
gene id: 1145276:T479_RS01900
uniprot id: A0A806LJN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS05055
gene id: 1145276:T479_RS05055
uniprot id: A0A806LLE2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS05995
gene id: 1145276:T479_RS05995
uniprot id: A0A806LFZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1145276:T479 RS11305
gene id: 1145276:T479_RS11305
uniprot id: A0A806LIH7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1145276:T479 RS00880
gene id: 1145276:T479_RS00880
uniprot id: A0A806LD51
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS05485
gene id: 1145276:T479_RS05485
uniprot id: A0A806LFR7
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04470
gene id: 1145276:T479_RS04470
uniprot id: A0A806LHK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1145276:T479 RS20850
gene id: 1145276:T479_RS20850
uniprot id: A0A806LN53
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS14125
gene id: 1145276:T479_RS14125
uniprot id: A0A806LQS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1145276:T479 RS06790
gene id: 1145276:T479_RS06790
uniprot id: A0A806LQ43
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS22550
gene id: 1145276:T479_RS22550
uniprot id: A0A806LVI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1145276:T479 RS21070
gene id: 1145276:T479_RS21070
uniprot id: A0A806LX37
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS04720
gene id: 1145276:T479_RS04720
uniprot id: A0A806LF83
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1145276:T479 RS05305
gene id: 1145276:T479_RS05305
uniprot id: A0A806LGZ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1145276:T479 RS21500
gene id: 1145276:T479_RS21500
uniprot id: A0A806LUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS08770
gene id: 1145276:T479_RS08770
uniprot id: A0A806LR43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1145276:T479 RS22625
gene id: 1145276:T479_RS22625
uniprot id: A0A806LP02
names: Similarity
messages: Belongs to the ParB family.

1145276:T479 RS13310
gene id: 1145276:T479_RS13310
uniprot id: A0A806LQB5
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS09620
gene id: 1145276:T479_RS09620
uniprot id: A0A806LRL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1145276:T479 RS03260
gene id: 1145276:T479_RS03260
uniprot id: A0A806LKE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1145276:T479 RS16700
gene id: 1145276:T479_RS16700
uniprot id: A0A806LNE1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1145276:T479 RS13615
gene id: 1145276:T479_RS13615
uniprot id: A0A806LV27
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1145276:T479 RS09805
gene id: 1145276:T479_RS09805
uniprot id: A0A806LNR1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1145276:T479 RS09075
gene id: 1145276:T479_RS09075
uniprot id: A0A806LND9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1145276:T479 RS17055
gene id: 1145276:T479_RS17055
uniprot id: A0A806LNL8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1145276:T479 RS14645
gene id: 1145276:T479_RS14645
uniprot id: A0A806LK69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1145276:T479 RS14545
gene id: 1145276:T479_RS14545
uniprot id: A0A806LK47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS14505
gene id: 1145276:T479_RS14505
uniprot id: A0A806LRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1145276:T479 RS02240
gene id: 1145276:T479_RS02240
uniprot id: A0A806LGI4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS19950
gene id: 1145276:T479_RS19950
uniprot id: A0A806LWI7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1145276:T479 RS05070
gene id: 1145276:T479_RS05070
uniprot id: A0A806LM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1145276:T479 RS06735
gene id: 1145276:T479_RS06735
uniprot id: A0A806LMZ3
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1145276:T479 RS21945
gene id: 1145276:T479_RS21945
uniprot id: A0A806LXK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1145276:T479 RS02630
gene id: 1145276:T479_RS02630
uniprot id: A0A806LK40
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1145276:T479 RS16565
gene id: 1145276:T479_RS16565
uniprot id: A0A806LL35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1145276:T479 RS09205
gene id: 1145276:T479_RS09205
uniprot id: A0A806LSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1145276:T479 RS08745
gene id: 1145276:T479_RS08745
uniprot id: A0A806LIL7
names: Subcellular Location Annotation
messages: Cell membrane

1145276:T479 RS13345
gene id: 1145276:T479_RS13345
uniprot id: A0A806LS25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1145276:T479 RS05785
gene id: 1145276:T479_RS05785
uniprot id: A0A806LMI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1145276:T479 RS15300
gene id: 1145276:T479_RS15300
uniprot id: A0A806LRF8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1145276:T479 RS01225
gene id: 1145276:T479_RS01225
uniprot id: A0A806LL22
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS00080
gene id: 1145276:T479_RS00080
uniprot id: A0A806LN63
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1145276:T479 RS19580
gene id: 1145276:T479_RS19580
uniprot id: A0A806LMH0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1145276:T479 RS08390
gene id: 1145276:T479_RS08390
uniprot id: A0A806LPP4
names: Similarity
messages: Belongs to the DapA family.

1145276:T479 RS18560
gene id: 1145276:T479_RS18560
uniprot id: A0A806LP74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS21730
gene id: 1145276:T479_RS21730
uniprot id: A0A806LV18
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1145276:T479 RS06715
gene id: 1145276:T479_RS06715
uniprot id: A0A806LHL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1145276:T479 RS07715
gene id: 1145276:T479_RS07715
uniprot id: A0A806LJ74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1145276:T479 RS22190
gene id: 1145276:T479_RS22190
uniprot id: A0A806LNS0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS13565
gene id: 1145276:T479_RS13565
uniprot id: A0A806LV16
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1145276:T479 RS05080
gene id: 1145276:T479_RS05080
uniprot id: A0A806LFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1145276:T479 RS08935
gene id: 1145276:T479_RS08935
uniprot id: A0A806LR75
names: Similarity
messages: Belongs to the SCO1/2 family.

1145276:T479 RS18570
gene id: 1145276:T479_RS18570
uniprot id: A0A806LT17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS02065
gene id: 1145276:T479_RS02065
uniprot id: A0A806LF12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS10660
gene id: 1145276:T479_RS10660
uniprot id: A0A806LI27
names: Similarity
messages: Belongs to the group II decarboxylase family.

1145276:T479 RS14965
gene id: 1145276:T479_RS14965
uniprot id: A0A806LML9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1145276:T479 RS15775
gene id: 1145276:T479_RS15775
uniprot id: A0A806LN01
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1145276:T479 RS22670
gene id: 1145276:T479_RS22670
uniprot id: A0A806LY51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1145276:T479 RS22070
gene id: 1145276:T479_RS22070
uniprot id: A0A806LQ14
names: Similarity
messages: Belongs to the CtsR family.

1145276:T479 RS00690
gene id: 1145276:T479_RS00690
uniprot id: A0A806LJ54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS22240
gene id: 1145276:T479_RS22240
uniprot id: A0A806LNT0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS00910
gene id: 1145276:T479_RS00910
uniprot id: A0A806LD96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1145276:T479 RS19560
gene id: 1145276:T479_RS19560
uniprot id: A0A806LPM9
names: Similarity
messages: Belongs to the UPF0435 family.

1145276:T479 RS01990
gene id: 1145276:T479_RS01990
uniprot id: A0A806LGG1
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS16690
gene id: 1145276:T479_RS16690
uniprot id: A0A806LV22
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS21385
gene id: 1145276:T479_RS21385
uniprot id: A0A806LQL4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1145276:T479 RS21880
gene id: 1145276:T479_RS21880
uniprot id: A0A806LZD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1145276:T479 RS00725
gene id: 1145276:T479_RS00725
uniprot id: A0A806LKV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS05945
gene id: 1145276:T479_RS05945
uniprot id: A0A806LFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1145276:T479 RS16550
gene id: 1145276:T479_RS16550
uniprot id: A0A806LS38
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1145276:T479 RS08460
gene id: 1145276:T479_RS08460
uniprot id: A0A806LN38
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS16480
gene id: 1145276:T479_RS16480
uniprot id: A0A806LUX8
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

1145276:T479 RS21760
gene id: 1145276:T479_RS21760
uniprot id: A0A806LPV5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1145276:T479 RS16705
gene id: 1145276:T479_RS16705
uniprot id: A0A806LTU5
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1145276:T479 RS15115
gene id: 1145276:T479_RS15115
uniprot id: A0A806LMP9
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1145276:T479 RS04535
gene id: 1145276:T479_RS04535
uniprot id: A0A806LL48
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS15770
gene id: 1145276:T479_RS15770
uniprot id: A0A806LKL6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1145276:T479 RS04595
gene id: 1145276:T479_RS04595
uniprot id: A0A806LL53
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1145276:T479 RS04725
gene id: 1145276:T479_RS04725
uniprot id: A0A806LHR4
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

1145276:T479 RS16675
gene id: 1145276:T479_RS16675
uniprot id: A0A806LL55
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS02920
gene id: 1145276:T479_RS02920
uniprot id: A0A806LQJ7
names: Subcellular Location Annotation
messages: Periplasm

1145276:T479 RS20715
gene id: 1145276:T479_RS20715
uniprot id: A0A806LQ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1145276:T479 RS04765
gene id: 1145276:T479_RS04765
uniprot id: A0A806LM14
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1145276:T479 RS01885
gene id: 1145276:T479_RS01885
uniprot id: A0A806LMI7
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS09885
gene id: 1145276:T479_RS09885
uniprot id: A0A806LT76
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1145276:T479 RS07535
gene id: 1145276:T479_RS07535
uniprot id: A0A806LGR3
names: Similarity
messages: Belongs to the HypD family.

1145276:T479 RS08125
gene id: 1145276:T479_RS08125
uniprot id: A0A806LNN1
names: Similarity
messages: Belongs to the UPF0178 family.

1145276:T479 RS16795
gene id: 1145276:T479_RS16795
uniprot id: A0A806LL30
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1145276:T479 RS22575
gene id: 1145276:T479_RS22575
uniprot id: A0A806LR66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1145276:T479 RS03570
gene id: 1145276:T479_RS03570
uniprot id: A0A806LLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS01055
gene id: 1145276:T479_RS01055
uniprot id: A0A806LFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1145276:T479 RS21235
gene id: 1145276:T479_RS21235
uniprot id: A0A806LUW0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS00745
gene id: 1145276:T479_RS00745
uniprot id: A0A806LD67
names: Subcellular Location Annotation
messages: Cell membrane

1145276:T479 RS06000
gene id: 1145276:T479_RS06000
uniprot id: A0A806LR69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1145276:T479 RS02685
gene id: 1145276:T479_RS02685
uniprot id: A0A806LFD7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1145276:T479 RS09315
gene id: 1145276:T479_RS09315
uniprot id: A0A806LP82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS10865
gene id: 1145276:T479_RS10865
uniprot id: A0A806LTT2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS16610
gene id: 1145276:T479_RS16610
uniprot id: A0A806LMD4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1145276:T479 RS02135
gene id: 1145276:T479_RS02135
uniprot id: A0A806LMN9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS05820
gene id: 1145276:T479_RS05820
uniprot id: A0A806LLU5
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS13695
gene id: 1145276:T479_RS13695
uniprot id: A0A806LS93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1145276:T479 RS10860
gene id: 1145276:T479_RS10860
uniprot id: A0A806LIB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS19840
gene id: 1145276:T479_RS19840
uniprot id: A0A806LY97
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1145276:T479 RS16750
gene id: 1145276:T479_RS16750
uniprot id: A0A806LNE7
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.

1145276:T479 RS02635
gene id: 1145276:T479_RS02635
uniprot id: A0A806LFC5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1145276:T479 RS14060
gene id: 1145276:T479_RS14060
uniprot id: A0A806LQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS13585
gene id: 1145276:T479_RS13585
uniprot id: A0A806LLX8
names: Similarity
messages: Belongs to the TlyA family.

1145276:T479 RS10485
gene id: 1145276:T479_RS10485
uniprot id: A0A806LQN5
names: Similarity
messages: Belongs to the gamma-type SASP family.

1145276:T479 RS04610
gene id: 1145276:T479_RS04610
uniprot id: A0A806LLY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1145276:T479 RS02555
gene id: 1145276:T479_RS02555
uniprot id: A0A806LPF1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS13985
gene id: 1145276:T479_RS13985
uniprot id: A0A806LTR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1145276:T479 RS15860
gene id: 1145276:T479_RS15860
uniprot id: A0A806LUQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1145276:T479 RS05275
gene id: 1145276:T479_RS05275
uniprot id: A0A806LMB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1145276:T479 RS15110
gene id: 1145276:T479_RS15110
uniprot id: A0A806LKA0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1145276:T479 RS07420
gene id: 1145276:T479_RS07420
uniprot id: A0A806LRY2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1145276:T479 RS08750
gene id: 1145276:T479_RS08750
uniprot id: A0A806LN82
names: Function
names: Similarity
messages: Belongs to the LutC/YkgG family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.

1145276:T479 RS14665
gene id: 1145276:T479_RS14665
uniprot id: A0A806LK22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1145276:T479 RS06365
gene id: 1145276:T479_RS06365
uniprot id: A0A806LM42
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1145276:T479 RS05085
gene id: 1145276:T479_RS05085
uniprot id: A0A806LHY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS14840
gene id: 1145276:T479_RS14840
uniprot id: A0A806LQE1
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1145276:T479 RS13065
gene id: 1145276:T479_RS13065
uniprot id: A0A806LQ59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1145276:T479 RS17240
gene id: 1145276:T479_RS17240
uniprot id: A0A806LT30
names: Similarity
messages: Belongs to the isochorismate synthase family.

1145276:T479 RS14630
gene id: 1145276:T479_RS14630
uniprot id: A0A806LR21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1145276:T479 RS09950
gene id: 1145276:T479_RS09950
uniprot id: A0A806LHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS01910
gene id: 1145276:T479_RS01910
uniprot id: A0A806LJQ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1145276:T479 RS04020
gene id: 1145276:T479_RS04020
uniprot id: A0A806LKU3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1145276:T479 RS15275
gene id: 1145276:T479_RS15275
uniprot id: A0A806LKD7
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS19945
gene id: 1145276:T479_RS19945
uniprot id: A0A806LU91
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1145276:T479 RS04715
gene id: 1145276:T479_RS04715
uniprot id: A0A806LP37
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1145276:T479 RS10190
gene id: 1145276:T479_RS10190
uniprot id: A0A806LPK7
names: Similarity
messages: Belongs to the UPF0045 family.

1145276:T479 RS08910
gene id: 1145276:T479_RS08910
uniprot id: A0A806LND5
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Autophosphorylated.
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1145276:T479 RS06045
gene id: 1145276:T479_RS06045
uniprot id: A0A806LLW4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS08340
gene id: 1145276:T479_RS08340
uniprot id: A0A806LN43
names: Similarity
messages: Belongs to the Dps family.

1145276:T479 RS20340
gene id: 1145276:T479_RS20340
uniprot id: A0A806LMT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1145276:T479 RS18450
gene id: 1145276:T479_RS18450
uniprot id: A0A806LLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS19465
gene id: 1145276:T479_RS19465
uniprot id: A0A806LTH2
names: Similarity
messages: Belongs to the UPF0374 family.

1145276:T479 RS15840
gene id: 1145276:T479_RS15840
uniprot id: A0A806LRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.
messages: Cell membrane
messages: Membrane

1145276:T479 RS07190
gene id: 1145276:T479_RS07190
uniprot id: A0A806LIY2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1145276:T479 RS09155
gene id: 1145276:T479_RS09155
uniprot id: A0A806LHA7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS05910
gene id: 1145276:T479_RS05910
uniprot id: A0A806LPP6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1145276:T479 RS21105
gene id: 1145276:T479_RS21105
uniprot id: A0A806LNB0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1145276:T479 RS04160
gene id: 1145276:T479_RS04160
uniprot id: A0A806LKX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1145276:T479 RS13720
gene id: 1145276:T479_RS13720
uniprot id: A0A806LV47
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1145276:T479 RS12970
gene id: 1145276:T479_RS12970
uniprot id: A0A806LQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS09195
gene id: 1145276:T479_RS09195
uniprot id: A0A806LPN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS20815
gene id: 1145276:T479_RS20815
uniprot id: A0A806LN18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1145276:T479 RS16310
gene id: 1145276:T479_RS16310
uniprot id: A0A806LKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1145276:T479 RS17130
gene id: 1145276:T479_RS17130
uniprot id: A0A806LMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1145276:T479 RS22600
gene id: 1145276:T479_RS22600
uniprot id: A0A806LNZ9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1145276:T479 RS08260
gene id: 1145276:T479_RS08260
uniprot id: A0A806LPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS22215
gene id: 1145276:T479_RS22215
uniprot id: A0A806LQZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1145276:T479 RS12910
gene id: 1145276:T479_RS12910
uniprot id: A0A806LUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS04485
gene id: 1145276:T479_RS04485
uniprot id: A0A806LGC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1145276:T479 RS13980
gene id: 1145276:T479_RS13980
uniprot id: A0A806LRD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1145276:T479 RS08590
gene id: 1145276:T479_RS08590
uniprot id: A0A806LNW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1145276:T479 RS20085
gene id: 1145276:T479_RS20085
uniprot id: A0A806LVF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1145276:T479 RS19545
gene id: 1145276:T479_RS19545
uniprot id: A0A806LU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1145276:T479 RS15875
gene id: 1145276:T479_RS15875
uniprot id: A0A806LTF5
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS22265
gene id: 1145276:T479_RS22265
uniprot id: A0A806LR05
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS05125
gene id: 1145276:T479_RS05125
uniprot id: A0A806LM83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1145276:T479 RS19985
gene id: 1145276:T479_RS19985
uniprot id: A0A806LMQ6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1145276:T479 RS19785
gene id: 1145276:T479_RS19785
uniprot id: A0A806LML4
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1145276:T479 RS20275
gene id: 1145276:T479_RS20275
uniprot id: A0A806LUF9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS04630
gene id: 1145276:T479_RS04630
uniprot id: A0A806LMU3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1145276:T479 RS06100
gene id: 1145276:T479_RS06100
uniprot id: A0A806LFY8
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04710
gene id: 1145276:T479_RS04710
uniprot id: A0A806LM06
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1145276:T479 RS12895
gene id: 1145276:T479_RS12895
uniprot id: A0A806LKG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS14605
gene id: 1145276:T479_RS14605
uniprot id: A0A806LRT2
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS03750
gene id: 1145276:T479_RS03750
uniprot id: A0A806LFX2
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS05750
gene id: 1145276:T479_RS05750
uniprot id: A0A806LNF0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS16605
gene id: 1145276:T479_RS16605
uniprot id: A0A806LS47
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1145276:T479 RS22120
gene id: 1145276:T479_RS22120
uniprot id: A0A806LUW8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1145276:T479 RS20750
gene id: 1145276:T479_RS20750
uniprot id: A0A806LYP7
names: Subunit
messages: Interacts directly with the sensor histidine kinase ComP and stimulates its activity.

1145276:T479 RS04410
gene id: 1145276:T479_RS04410
uniprot id: A0A806LF17
names: Similarity
messages: Belongs to the YggT family.

1145276:T479 RS04005
gene id: 1145276:T479_RS04005
uniprot id: A0A806LMH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1145276:T479 RS15715
gene id: 1145276:T479_RS15715
uniprot id: A0A806LKK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1145276:T479 RS02765
gene id: 1145276:T479_RS02765
uniprot id: A0A806LE61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1145276:T479 RS04360
gene id: 1145276:T479_RS04360
uniprot id: A0A806LF09
names: Similarity
messages: Belongs to the UPF0749 family.

1145276:T479 RS20630
gene id: 1145276:T479_RS20630
uniprot id: A0A806LN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1145276:T479 RS19635
gene id: 1145276:T479_RS19635
uniprot id: A0A806LU35
names: Similarity
messages: Belongs to the peptidase M29 family.

1145276:T479 RS08130
gene id: 1145276:T479_RS08130
uniprot id: A0A806LQT4
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1145276:T479 RS02570
gene id: 1145276:T479_RS02570
uniprot id: A0A806LE17
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS06040
gene id: 1145276:T479_RS06040
uniprot id: A0A806LHA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS18410
gene id: 1145276:T479_RS18410
uniprot id: A0A806LP40
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1145276:T479 RS15380
gene id: 1145276:T479_RS15380
uniprot id: A0A806LMU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1145276:T479 RS08205
gene id: 1145276:T479_RS08205
uniprot id: A0A806LN24
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS12435
gene id: 1145276:T479_RS12435
uniprot id: A0A806LPU6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS22250
gene id: 1145276:T479_RS22250
uniprot id: A0A806LVB6
names: Subcellular Location Annotation
messages: Cell membrane

1145276:T479 RS18960
gene id: 1145276:T479_RS18960
uniprot id: A0A806LNI6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1145276:T479 RS16615
gene id: 1145276:T479_RS16615
uniprot id: A0A806LS21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1145276:T479 RS04580
gene id: 1145276:T479_RS04580
uniprot id: A0A806LMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS21580
gene id: 1145276:T479_RS21580
uniprot id: A0A806LW60
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1145276:T479 RS20725
gene id: 1145276:T479_RS20725
uniprot id: A0A806LU70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1145276:T479 RS10720
gene id: 1145276:T479_RS10720
uniprot id: A0A806LKM8
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS02710
gene id: 1145276:T479_RS02710
uniprot id: A0A806LN05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1145276:T479 RS01875
gene id: 1145276:T479_RS01875
uniprot id: A0A806LP12
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1145276:T479 RS13300
gene id: 1145276:T479_RS13300
uniprot id: A0A806LQB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1145276:T479 RS12475
gene id: 1145276:T479_RS12475
uniprot id: A0A806LPX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1145276:T479 RS12525
gene id: 1145276:T479_RS12525
uniprot id: A0A806LLB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1145276:T479 RS19565
gene id: 1145276:T479_RS19565
uniprot id: A0A806LV41
names: Similarity
messages: Belongs to the MotB family.

1145276:T479 RS07150
gene id: 1145276:T479_RS07150
uniprot id: A0A806LMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1145276:T479 RS13060
gene id: 1145276:T479_RS13060
uniprot id: A0A806LKJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS18920
gene id: 1145276:T479_RS18920
uniprot id: A0A806LM81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1145276:T479 RS08800
gene id: 1145276:T479_RS08800
uniprot id: A0A806LN92
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1145276:T479 RS04795
gene id: 1145276:T479_RS04795
uniprot id: A0A806LLA8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1145276:T479 RS18525
gene id: 1145276:T479_RS18525
uniprot id: A0A806LN91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1145276:T479 RS20210
gene id: 1145276:T479_RS20210
uniprot id: A0A806LYG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS09865
gene id: 1145276:T479_RS09865
uniprot id: A0A806LHU2
names: Similarity
messages: Belongs to the peptidase C59 family.

1145276:T479 RS15000
gene id: 1145276:T479_RS15000
uniprot id: A0A806LRZ7
names: Similarity
messages: Belongs to the UPF0473 family.

1145276:T479 RS12365
gene id: 1145276:T479_RS12365
uniprot id: A0A806LL85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

1145276:T479 RS16710
gene id: 1145276:T479_RS16710
uniprot id: A0A806LS67
names: Similarity
messages: Belongs to the citrate synthase family.

1145276:T479 RS00790
gene id: 1145276:T479_RS00790
uniprot id: A0A806LJ59
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1145276:T479 RS00200
gene id: 1145276:T479_RS00200
uniprot id: A0A806LLR8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1145276:T479 RS04740
gene id: 1145276:T479_RS04740
uniprot id: A0A806LGM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1145276:T479 RS04875
gene id: 1145276:T479_RS04875
uniprot id: A0A806LP67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1145276:T479 RS21875
gene id: 1145276:T479_RS21875
uniprot id: A0A806LNL7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1145276:T479 RS02525
gene id: 1145276:T479_RS02525
uniprot id: A0A806LGM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS15080
gene id: 1145276:T479_RS15080
uniprot id: A0A806LLP2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1145276:T479 RS04605
gene id: 1145276:T479_RS04605
uniprot id: A0A806LQG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1145276:T479 RS04660
gene id: 1145276:T479_RS04660
uniprot id: A0A806LLZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1145276:T479 RS20495
gene id: 1145276:T479_RS20495
uniprot id: A0A806LWS8
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS22035
gene id: 1145276:T479_RS22035
uniprot id: A0A806LZF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1145276:T479 RS16725
gene id: 1145276:T479_RS16725
uniprot id: A0A806LL63
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1145276:T479 RS17220
gene id: 1145276:T479_RS17220
uniprot id: A0A806LMQ2
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1145276:T479 RS00720
gene id: 1145276:T479_RS00720
uniprot id: A0A806LFT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS15295
gene id: 1145276:T479_RS15295
uniprot id: A0A806LLT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1145276:T479 RS21350
gene id: 1145276:T479_RS21350
uniprot id: A0A806LPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1145276:T479 RS05740
gene id: 1145276:T479_RS05740
uniprot id: A0A806LFS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS11390
gene id: 1145276:T479_RS11390
uniprot id: A0A806LIE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS06355
gene id: 1145276:T479_RS06355
uniprot id: A0A806LIJ0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1145276:T479 RS04135
gene id: 1145276:T479_RS04135
uniprot id: A0A806LLQ5
names: Similarity
messages: Belongs to the UPF0358 family.

1145276:T479 RS13210
gene id: 1145276:T479_RS13210
uniprot id: A0A806LQ91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1145276:T479 RS10000
gene id: 1145276:T479_RS10000
uniprot id: A0A806LW02
names: Similarity
messages: Belongs to the arginase family.

1145276:T479 RS19770
gene id: 1145276:T479_RS19770
uniprot id: A0A806LTN5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS16290
gene id: 1145276:T479_RS16290
uniprot id: A0A806LRY3
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1145276:T479 RS06175
gene id: 1145276:T479_RS06175
uniprot id: A0A806LPT3
names: Similarity
messages: Belongs to the DinB family.

1145276:T479 RS18655
gene id: 1145276:T479_RS18655
uniprot id: A0A806LP91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

1145276:T479 RS10870
gene id: 1145276:T479_RS10870
uniprot id: A0A806LPY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1145276:T479 RS20545
gene id: 1145276:T479_RS20545
uniprot id: A0A806LMW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS10100
gene id: 1145276:T479_RS10100
uniprot id: A0A806LHQ1
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS09340
gene id: 1145276:T479_RS09340
uniprot id: A0A806LNM5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS07205
gene id: 1145276:T479_RS07205
uniprot id: A0A806LHT1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1145276:T479 RS22285
gene id: 1145276:T479_RS22285
uniprot id: A0A806LV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1145276:T479 RS22160
gene id: 1145276:T479_RS22160
uniprot id: A0A806LQY8
names: Similarity
messages: Belongs to the leucine-binding protein family.

1145276:T479 RS14675
gene id: 1145276:T479_RS14675
uniprot id: A0A806LSS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1145276:T479 RS05415
gene id: 1145276:T479_RS05415
uniprot id: A0A806LLN2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1145276:T479 RS05295
gene id: 1145276:T479_RS05295
uniprot id: A0A806LN79
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS02155
gene id: 1145276:T479_RS02155
uniprot id: A0A806LJU0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1145276:T479 RS20375
gene id: 1145276:T479_RS20375
uniprot id: A0A806LYJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1145276:T479 RS13245
gene id: 1145276:T479_RS13245
uniprot id: A0A806LRZ8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1145276:T479 RS04370
gene id: 1145276:T479_RS04370
uniprot id: A0A806LMP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1145276:T479 RS05805
gene id: 1145276:T479_RS05805
uniprot id: A0A806LI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1145276:T479 RS22535
gene id: 1145276:T479_RS22535
uniprot id: A0A806LV69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1145276:T479 RS19895
gene id: 1145276:T479_RS19895
uniprot id: A0A806LU80
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1145276:T479 RS12045
gene id: 1145276:T479_RS12045
uniprot id: A0A806LK29
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

1145276:T479 RS10915
gene id: 1145276:T479_RS10915
uniprot id: A0A806LTU2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1145276:T479 RS02280
gene id: 1145276:T479_RS02280
uniprot id: A0A806LKS4
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS22640
gene id: 1145276:T479_RS22640
uniprot id: A0A806LV62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

1145276:T479 RS11250
gene id: 1145276:T479_RS11250
uniprot id: A0A806LSD3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS00320
gene id: 1145276:T479_RS00320
uniprot id: A0A806LCU1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1145276:T479 RS16495
gene id: 1145276:T479_RS16495
uniprot id: A0A806LTP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS10420
gene id: 1145276:T479_RS10420
uniprot id: A0A806LS04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS04800
gene id: 1145276:T479_RS04800
uniprot id: A0A806LGN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS20020
gene id: 1145276:T479_RS20020
uniprot id: A0A806LMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1145276:T479 RS05395
gene id: 1145276:T479_RS05395
uniprot id: A0A806LPH3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1145276:T479 RS00335
gene id: 1145276:T479_RS00335
uniprot id: A0A806LIW9
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1145276:T479 RS16410
gene id: 1145276:T479_RS16410
uniprot id: A0A806LRZ2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1145276:T479 RS13040
gene id: 1145276:T479_RS13040
uniprot id: A0A806LJ41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1145276:T479 RS18740
gene id: 1145276:T479_RS18740
uniprot id: A0A806LVY8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1145276:T479 RS13595
gene id: 1145276:T479_RS13595
uniprot id: A0A806LQH6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1145276:T479 RS17630
gene id: 1145276:T479_RS17630
uniprot id: A0A806LT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS04980
gene id: 1145276:T479_RS04980
uniprot id: A0A806LFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1145276:T479 RS05475
gene id: 1145276:T479_RS05475
uniprot id: A0A806LLM9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1145276:T479 RS05955
gene id: 1145276:T479_RS05955
uniprot id: A0A806LML2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1145276:T479 RS20460
gene id: 1145276:T479_RS20460
uniprot id: A0A806LVL0
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

1145276:T479 RS20880
gene id: 1145276:T479_RS20880
uniprot id: A0A806LVT7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1145276:T479 RS05855
gene id: 1145276:T479_RS05855
uniprot id: A0A806LFU4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1145276:T479 RS15925
gene id: 1145276:T479_RS15925
uniprot id: A0A806LUR2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS00235
gene id: 1145276:T479_RS00235
uniprot id: A0A806LIV0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1145276:T479 RS05240
gene id: 1145276:T479_RS05240
uniprot id: A0A806LI09
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS07470
gene id: 1145276:T479_RS07470
uniprot id: A0A806LRZ1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1145276:T479 RS19470
gene id: 1145276:T479_RS19470
uniprot id: A0A806LTH5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1145276:T479 RS04425
gene id: 1145276:T479_RS04425
uniprot id: A0A806LL31
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1145276:T479 RS12965
gene id: 1145276:T479_RS12965
uniprot id: A0A806LUN6
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1145276:T479 RS00710
gene id: 1145276:T479_RS00710
uniprot id: A0A806LM07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1145276:T479 RS19930
gene id: 1145276:T479_RS19930
uniprot id: A0A806LTS8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1145276:T479 RS10065
gene id: 1145276:T479_RS10065
uniprot id: A0A806LNX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1145276:T479 RS06655
gene id: 1145276:T479_RS06655
uniprot id: A0A806LM85
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1145276:T479 RS06295
gene id: 1145276:T479_RS06295
uniprot id: A0A806LIH9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS17840
gene id: 1145276:T479_RS17840
uniprot id: A0A806LSM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1145276:T479 RS20350
gene id: 1145276:T479_RS20350
uniprot id: A0A806LVK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1145276:T479 RS16930
gene id: 1145276:T479_RS16930
uniprot id: A0A806LWQ4
names: Similarity
messages: Belongs to the histone deacetylase family.

1145276:T479 RS02535
gene id: 1145276:T479_RS02535
uniprot id: A0A806LK18
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1145276:T479 RS00445
gene id: 1145276:T479_RS00445
uniprot id: A0A806LKQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1145276:T479 RS15900
gene id: 1145276:T479_RS15900
uniprot id: A0A806LQE6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1145276:T479 RS05160
gene id: 1145276:T479_RS05160
uniprot id: A0A806LLG5
names: Similarity
messages: Belongs to the peptidase M16 family.

1145276:T479 RS16375
gene id: 1145276:T479_RS16375
uniprot id: A0A806LSJ6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1145276:T479 RS16880
gene id: 1145276:T479_RS16880
uniprot id: A0A806LWP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS06115
gene id: 1145276:T479_RS06115
uniprot id: A0A806LRN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1145276:T479 RS08255
gene id: 1145276:T479_RS08255
uniprot id: A0A806LJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS13205
gene id: 1145276:T479_RS13205
uniprot id: A0A806LSH5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS15785
gene id: 1145276:T479_RS15785
uniprot id: A0A806LRS4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1145276:T479 RS15760
gene id: 1145276:T479_RS15760
uniprot id: A0A806LSB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS10620
gene id: 1145276:T479_RS10620
uniprot id: A0A806LP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1145276:T479 RS12845
gene id: 1145276:T479_RS12845
uniprot id: A0A806LKF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS11240
gene id: 1145276:T479_RS11240
uniprot id: A0A806LTY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1145276:T479 RS20720
gene id: 1145276:T479_RS20720
uniprot id: A0A806LVQ9
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. MtnX family.
messages: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

1145276:T479 RS10900
gene id: 1145276:T479_RS10900
uniprot id: A0A806LJN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS08465
gene id: 1145276:T479_RS08465
uniprot id: A0A806LH73
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1145276:T479 RS04180
gene id: 1145276:T479_RS04180
uniprot id: A0A806LQ98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS20125
gene id: 1145276:T479_RS20125
uniprot id: A0A806LMP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1145276:T479 RS14525
gene id: 1145276:T479_RS14525
uniprot id: A0A806LSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS04385
gene id: 1145276:T479_RS04385
uniprot id: A0A806LL13
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1145276:T479 RS02660
gene id: 1145276:T479_RS02660
uniprot id: A0A806LMZ5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS12705
gene id: 1145276:T479_RS12705
uniprot id: A0A806LIY7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1145276:T479 RS05235
gene id: 1145276:T479_RS05235
uniprot id: A0A806LFJ7
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04730
gene id: 1145276:T479_RS04730
uniprot id: A0A806LMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1145276:T479 RS02715
gene id: 1145276:T479_RS02715
uniprot id: A0A806LE52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1145276:T479 RS10145
gene id: 1145276:T479_RS10145
uniprot id: A0A806LRV4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1145276:T479 RS07250
gene id: 1145276:T479_RS07250
uniprot id: A0A806LMH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1145276:T479 RS08400
gene id: 1145276:T479_RS08400
uniprot id: A0A806LIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS16730
gene id: 1145276:T479_RS16730
uniprot id: A0A806LWL1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS12720
gene id: 1145276:T479_RS12720
uniprot id: A0A806LSG7
names: Similarity
messages: Belongs to the peptidase S13 family.

1145276:T479 RS07270
gene id: 1145276:T479_RS07270
uniprot id: A0A806LRV1
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1145276:T479 RS06605
gene id: 1145276:T479_RS06605
uniprot id: A0A806LHK0
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS18755
gene id: 1145276:T479_RS18755
uniprot id: A0A806LUS4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1145276:T479 RS13480
gene id: 1145276:T479_RS13480
uniprot id: A0A806LJE4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1145276:T479 RS07335
gene id: 1145276:T479_RS07335
uniprot id: A0A806LGF1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1145276:T479 RS00865
gene id: 1145276:T479_RS00865
uniprot id: A0A806LNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1145276:T479 RS20995
gene id: 1145276:T479_RS20995
uniprot id: A0A806LPI6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1145276:T479 RS14750
gene id: 1145276:T479_RS14750
uniprot id: A0A806LR47
names: Similarity
messages: Belongs to the peptidase S8 family.

1145276:T479 RS14355
gene id: 1145276:T479_RS14355
uniprot id: A0A806LJW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1145276:T479 RS00300
gene id: 1145276:T479_RS00300
uniprot id: A0A806LCZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1145276:T479 RS15805
gene id: 1145276:T479_RS15805
uniprot id: A0A806LSD0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1145276:T479 RS18385
gene id: 1145276:T479_RS18385
uniprot id: A0A806LLW9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1145276:T479 RS18580
gene id: 1145276:T479_RS18580
uniprot id: A0A806LT16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS14600
gene id: 1145276:T479_RS14600
uniprot id: A0A806LVL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1145276:T479 RS05900
gene id: 1145276:T479_RS05900
uniprot id: A0A806LMK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1145276:T479 RS06805
gene id: 1145276:T479_RS06805
uniprot id: A0A806LNW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS13195
gene id: 1145276:T479_RS13195
uniprot id: A0A806LQ95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacB/CdaS subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Probably oligomerizes.

1145276:T479 RS21595
gene id: 1145276:T479_RS21595
uniprot id: A0A806LUN4
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1145276:T479 RS07845
gene id: 1145276:T479_RS07845
uniprot id: A0A806LGW7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS04885
gene id: 1145276:T479_RS04885
uniprot id: A0A806LHU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1145276:T479 RS00435
gene id: 1145276:T479_RS00435
uniprot id: A0A806LCW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1145276:T479 RS03940
gene id: 1145276:T479_RS03940
uniprot id: A0A806LHB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1145276:T479 RS18880
gene id: 1145276:T479_RS18880
uniprot id: A0A806LM69
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS02595
gene id: 1145276:T479_RS02595
uniprot id: A0A806LE68
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1145276:T479 RS22515
gene id: 1145276:T479_RS22515
uniprot id: A0A806LR56
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS03350
gene id: 1145276:T479_RS03350
uniprot id: A0A806LKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

1145276:T479 RS17175
gene id: 1145276:T479_RS17175
uniprot id: A0A806LSG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS00870
gene id: 1145276:T479_RS00870
uniprot id: A0A806LK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS03315
gene id: 1145276:T479_RS03315
uniprot id: A0A806LEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1145276:T479 RS23635
gene id: 1145276:T479_RS23635
uniprot id: A0A806LP69
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS04570
gene id: 1145276:T479_RS04570
uniprot id: A0A806LF50
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS04500
gene id: 1145276:T479_RS04500
uniprot id: A0A806LQE3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS07435
gene id: 1145276:T479_RS07435
uniprot id: A0A806LGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1145276:T479 RS18475
gene id: 1145276:T479_RS18475
uniprot id: A0A806LN78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1145276:T479 RS21100
gene id: 1145276:T479_RS21100
uniprot id: A0A806LUF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1145276:T479 RS06065
gene id: 1145276:T479_RS06065
uniprot id: A0A806LPS3
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS08645
gene id: 1145276:T479_RS08645
uniprot id: A0A806LR22
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS17640
gene id: 1145276:T479_RS17640
uniprot id: A0A806LLF2
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1145276:T479 RS11665
gene id: 1145276:T479_RS11665
uniprot id: A0A806LPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

1145276:T479 RS10845
gene id: 1145276:T479_RS10845
uniprot id: A0A806LPB2
names: Similarity
messages: Belongs to the TelA family.

1145276:T479 RS21430
gene id: 1145276:T479_RS21430
uniprot id: A0A806LZ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS04825
gene id: 1145276:T479_RS04825
uniprot id: A0A806LP57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1145276:T479 RS04280
gene id: 1145276:T479_RS04280
uniprot id: A0A806LKZ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1145276:T479 RS03525
gene id: 1145276:T479_RS03525
uniprot id: A0A806LNF9
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

1145276:T479 RS20650
gene id: 1145276:T479_RS20650
uniprot id: A0A806LMY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1145276:T479 RS20910
gene id: 1145276:T479_RS20910
uniprot id: A0A806LUQ7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1145276:T479 RS01150
gene id: 1145276:T479_RS01150
uniprot id: A0A806LK70
names: Similarity
messages: Belongs to the UPF0398 family.

1145276:T479 RS00495
gene id: 1145276:T479_RS00495
uniprot id: A0A806LKR1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1145276:T479 RS14970
gene id: 1145276:T479_RS14970
uniprot id: A0A806LSX9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS18080
gene id: 1145276:T479_RS18080
uniprot id: A0A806LVN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1145276:T479 RS05285
gene id: 1145276:T479_RS05285
uniprot id: A0A806LFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1145276:T479 RS00105
gene id: 1145276:T479_RS00105
uniprot id: A0A806LKJ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS22545
gene id: 1145276:T479_RS22545
uniprot id: A0A806LZQ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1145276:T479 RS00620
gene id: 1145276:T479_RS00620
uniprot id: A0A806LEC2
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04635
gene id: 1145276:T479_RS04635
uniprot id: A0A806LL70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1145276:T479 RS07595
gene id: 1145276:T479_RS07595
uniprot id: A0A806LND1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1145276:T479 RS09300
gene id: 1145276:T479_RS09300
uniprot id: A0A806LNI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1145276:T479 RS16465
gene id: 1145276:T479_RS16465
uniprot id: A0A806LL14
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

1145276:T479 RS09540
gene id: 1145276:T479_RS09540
uniprot id: A0A806LNM0
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS12915
gene id: 1145276:T479_RS12915
uniprot id: A0A806LQS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS00715
gene id: 1145276:T479_RS00715
uniprot id: A0A806LD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1145276:T479 RS03415
gene id: 1145276:T479_RS03415
uniprot id: A0A806LEK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS19975
gene id: 1145276:T479_RS19975
uniprot id: A0A806LP07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1145276:T479 RS10700
gene id: 1145276:T479_RS10700
uniprot id: A0A806LPU7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1145276:T479 RS02695
gene id: 1145276:T479_RS02695
uniprot id: A0A806LE90
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS00145
gene id: 1145276:T479_RS00145
uniprot id: A0A806LCR3
names: Similarity
messages: Belongs to the DCK/DGK family.

1145276:T479 RS07720
gene id: 1145276:T479_RS07720
uniprot id: A0A806LPB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS06825
gene id: 1145276:T479_RS06825
uniprot id: A0A806LGB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS20675
gene id: 1145276:T479_RS20675
uniprot id: A0A806LU61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1145276:T479 RS10885
gene id: 1145276:T479_RS10885
uniprot id: A0A806LKQ1
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS04890
gene id: 1145276:T479_RS04890
uniprot id: A0A806LMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1145276:T479 RS20890
gene id: 1145276:T479_RS20890
uniprot id: A0A806LPG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1145276:T479 RS16800
gene id: 1145276:T479_RS16800
uniprot id: A0A806LNG5
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS17995
gene id: 1145276:T479_RS17995
uniprot id: A0A806LSS2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1145276:T479 RS05645
gene id: 1145276:T479_RS05645
uniprot id: A0A806LI84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS20330
gene id: 1145276:T479_RS20330
uniprot id: A0A806LUG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1145276:T479 RS14390
gene id: 1145276:T479_RS14390
uniprot id: A0A806LRP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1145276:T479 RS17015
gene id: 1145276:T479_RS17015
uniprot id: A0A806LSD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS05400
gene id: 1145276:T479_RS05400
uniprot id: A0A806LFM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS04495
gene id: 1145276:T479_RS04495
uniprot id: A0A806LF73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1145276:T479 RS17860
gene id: 1145276:T479_RS17860
uniprot id: A0A806LVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS00740
gene id: 1145276:T479_RS00740
uniprot id: A0A806LJ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS13685
gene id: 1145276:T479_RS13685
uniprot id: A0A806LJI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1145276:T479 RS03425
gene id: 1145276:T479_RS03425
uniprot id: A0A806LLC0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
messages: Homodimer.
messages: The N-terminal domain has binding sites for ComK and probably for unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1145276:T479 RS13255
gene id: 1145276:T479_RS13255
uniprot id: A0A806LKP4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1145276:T479 RS16315
gene id: 1145276:T479_RS16315
uniprot id: A0A806LWD4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1145276:T479 RS10155
gene id: 1145276:T479_RS10155
uniprot id: A0A806LKD4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1145276:T479 RS15010
gene id: 1145276:T479_RS15010
uniprot id: A0A806LK81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1145276:T479 RS04330
gene id: 1145276:T479_RS04330
uniprot id: A0A806LG99
names: Similarity
messages: Belongs to the transpeptidase family.

1145276:T479 RS20090
gene id: 1145276:T479_RS20090
uniprot id: A0A806LTU9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1145276:T479 RS17395
gene id: 1145276:T479_RS17395
uniprot id: A0A806LLH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1145276:T479 RS20840
gene id: 1145276:T479_RS20840
uniprot id: A0A806LPF8
names: Similarity
messages: Belongs to the UPF0111 family.

1145276:T479 RS04845
gene id: 1145276:T479_RS04845
uniprot id: A0A806LLB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1145276:T479 RS16805
gene id: 1145276:T479_RS16805
uniprot id: A0A806LTW8
names: Similarity
messages: Belongs to the peptidase S49 family.

1145276:T479 RS16560
gene id: 1145276:T479_RS16560
uniprot id: A0A806LS17
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS16555
gene id: 1145276:T479_RS16555
uniprot id: A0A806LMC4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1145276:T479 RS15335
gene id: 1145276:T479_RS15335
uniprot id: A0A806LT48
names: Similarity
messages: Belongs to the UPF0735 family.

1145276:T479 RS17575
gene id: 1145276:T479_RS17575
uniprot id: A0A806LWZ0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS02620
gene id: 1145276:T479_RS02620
uniprot id: A0A806LGP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1145276:T479 RS06450
gene id: 1145276:T479_RS06450
uniprot id: A0A806LPY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1145276:T479 RS14165
gene id: 1145276:T479_RS14165
uniprot id: A0A806LQT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1145276:T479 RS20795
gene id: 1145276:T479_RS20795
uniprot id: A0A806LN45
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1145276:T479 RS22540
gene id: 1145276:T479_RS22540
uniprot id: A0A806LNZ0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1145276:T479 RS04950
gene id: 1145276:T479_RS04950
uniprot id: A0A806LGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1145276:T479 RS15150
gene id: 1145276:T479_RS15150
uniprot id: A0A806LS19
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1145276:T479 RS18660
gene id: 1145276:T479_RS18660
uniprot id: A0A806LUQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS21010
gene id: 1145276:T479_RS21010
uniprot id: A0A806LYV2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1145276:T479 RS04545
gene id: 1145276:T479_RS04545
uniprot id: A0A806LL43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS08060
gene id: 1145276:T479_RS08060
uniprot id: A0A806LMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1145276:T479 RS15730
gene id: 1145276:T479_RS15730
uniprot id: A0A806LRR2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1145276:T479 RS01045
gene id: 1145276:T479_RS01045
uniprot id: A0A806LM48
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS04390
gene id: 1145276:T479_RS04390
uniprot id: A0A806LF47
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1145276:T479 RS10820
gene id: 1145276:T479_RS10820
uniprot id: A0A806LPX1
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS22720
gene id: 1145276:T479_RS22720
uniprot id: A0A806LPB0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1145276:T479 RS00350
gene id: 1145276:T479_RS00350
uniprot id: A0A806LD01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1145276:T479 RS10995
gene id: 1145276:T479_RS10995
uniprot id: A0A806LSA6
names: Similarity
messages: Belongs to the peptidase S33 family.

1145276:T479 RS11355
gene id: 1145276:T479_RS11355
uniprot id: A0A806LPF5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS10015
gene id: 1145276:T479_RS10015
uniprot id: A0A806LHV7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS13320
gene id: 1145276:T479_RS13320
uniprot id: A0A806LUW2
names: Similarity
messages: Belongs to the peptidase S8 family.

1145276:T479 RS20875
gene id: 1145276:T479_RS20875
uniprot id: A0A806LQC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1145276:T479 RS14895
gene id: 1145276:T479_RS14895
uniprot id: A0A806LVR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS05570
gene id: 1145276:T479_RS05570
uniprot id: A0A806LFR0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS12555
gene id: 1145276:T479_RS12555
uniprot id: A0A806LJ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS17045
gene id: 1145276:T479_RS17045
uniprot id: A0A806LV86
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS19870
gene id: 1145276:T479_RS19870
uniprot id: A0A806LVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS14375
gene id: 1145276:T479_RS14375
uniprot id: A0A806LLB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1145276:T479 RS05210
gene id: 1145276:T479_RS05210
uniprot id: A0A806LLH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1145276:T479 RS17385
gene id: 1145276:T479_RS17385
uniprot id: A0A806LSF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1145276:T479 RS22085
gene id: 1145276:T479_RS22085
uniprot id: A0A806LZG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1145276:T479 RS13725
gene id: 1145276:T479_RS13725
uniprot id: A0A806LR90
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS03060
gene id: 1145276:T479_RS03060
uniprot id: A0A806LL54
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS13510
gene id: 1145276:T479_RS13510
uniprot id: A0A806LJK6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1145276:T479 RS04520
gene id: 1145276:T479_RS04520
uniprot id: A0A806LHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS05020
gene id: 1145276:T479_RS05020
uniprot id: A0A806LM63
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1145276:T479 RS07085
gene id: 1145276:T479_RS07085
uniprot id: A0A806LGD2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1145276:T479 RS09215
gene id: 1145276:T479_RS09215
uniprot id: A0A806LRD8
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS21605
gene id: 1145276:T479_RS21605
uniprot id: A0A806LZ84
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1145276:T479 RS00490
gene id: 1145276:T479_RS00490
uniprot id: A0A806LFP9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1145276:T479 RS14920
gene id: 1145276:T479_RS14920
uniprot id: A0A806LSX0
names: Similarity
messages: Belongs to the sigma-70 factor family.

1145276:T479 RS22045
gene id: 1145276:T479_RS22045
uniprot id: A0A806LXN1
names: Similarity
messages: Belongs to the ycf81 family.

1145276:T479 RS18125
gene id: 1145276:T479_RS18125
uniprot id: A0A806LTF0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS16640
gene id: 1145276:T479_RS16640
uniprot id: A0A806LKZ8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1145276:T479 RS15780
gene id: 1145276:T479_RS15780
uniprot id: A0A806LTD0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS05970
gene id: 1145276:T479_RS05970
uniprot id: A0A806LIC9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1145276:T479 RS05540
gene id: 1145276:T479_RS05540
uniprot id: A0A806LLN9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS21780
gene id: 1145276:T479_RS21780
uniprot id: A0A806LV28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1145276:T479 RS00285
gene id: 1145276:T479_RS00285
uniprot id: A0A806LIW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS03330
gene id: 1145276:T479_RS03330
uniprot id: A0A806LNC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1145276:T479 RS10835
gene id: 1145276:T479_RS10835
uniprot id: A0A806LKP2
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS14020
gene id: 1145276:T479_RS14020
uniprot id: A0A806LJU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

1145276:T479 RS21895
gene id: 1145276:T479_RS21895
uniprot id: A0A806LNJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1145276:T479 RS05735
gene id: 1145276:T479_RS05735
uniprot id: A0A806LX13
names: Similarity
messages: Belongs to the thioesterase family.

1145276:T479 RS03470
gene id: 1145276:T479_RS03470
uniprot id: A0A806LPV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS06025
gene id: 1145276:T479_RS06025
uniprot id: A0A806LID9
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04440
gene id: 1145276:T479_RS04440
uniprot id: A0A806LF59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1145276:T479 RS18890
gene id: 1145276:T479_RS18890
uniprot id: A0A806LTU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some proteins.

1145276:T479 RS04140
gene id: 1145276:T479_RS04140
uniprot id: A0A806LNS7
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS15290
gene id: 1145276:T479_RS15290
uniprot id: A0A806LRH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1145276:T479 RS20570
gene id: 1145276:T479_RS20570
uniprot id: A0A806LPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1145276:T479 RS21080
gene id: 1145276:T479_RS21080
uniprot id: A0A806LQF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1145276:T479 RS19750
gene id: 1145276:T479_RS19750
uniprot id: A0A806LWE5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS08425
gene id: 1145276:T479_RS08425
uniprot id: A0A806LQY1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1145276:T479 RS04735
gene id: 1145276:T479_RS04735
uniprot id: A0A806LL98
names: Similarity
messages: Belongs to the fabD family.

1145276:T479 RS00025
gene id: 1145276:T479_RS00025
uniprot id: A0A806LKI2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1145276:T479 RS08725
gene id: 1145276:T479_RS08725
uniprot id: A0A806LH15
names: Similarity
messages: Belongs to the peptidase S8 family.

1145276:T479 RS22880
gene id: 1145276:T479_RS22880
uniprot id: A0A806LU86
names: Similarity
messages: Belongs to the peptidase S14 family.

1145276:T479 RS04785
gene id: 1145276:T479_RS04785
uniprot id: A0A806LHS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1145276:T479 RS14330
gene id: 1145276:T479_RS14330
uniprot id: A0A806LQV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1145276:T479 RS18700
gene id: 1145276:T479_RS18700
uniprot id: A0A806LM02
names: Function
names: Subunit
messages: Homodimer.
messages: Negative regulator of protease production and sporulation.

1145276:T479 RS16530
gene id: 1145276:T479_RS16530
uniprot id: A0A806LUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS02025
gene id: 1145276:T479_RS02025
uniprot id: A0A806LKM6
names: Similarity
messages: Belongs to the nitroreductase family.

1145276:T479 RS13035
gene id: 1145276:T479_RS13035
uniprot id: A0A806LT52
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1145276:T479 RS03075
gene id: 1145276:T479_RS03075
uniprot id: A0A806LGW6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

1145276:T479 RS01305
gene id: 1145276:T479_RS01305
uniprot id: A0A806LNR5
names: Similarity
messages: Belongs to the AHA1 family.

1145276:T479 RS07555
gene id: 1145276:T479_RS07555
uniprot id: A0A806LGF5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1145276:T479 RS03910
gene id: 1145276:T479_RS03910
uniprot id: A0A806LKS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS20645
gene id: 1145276:T479_RS20645
uniprot id: A0A806LWV8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1145276:T479 RS08760
gene id: 1145276:T479_RS08760
uniprot id: A0A806LSM2
names: Function
names: Similarity
messages: Belongs to the LutA/YkgE family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.

1145276:T479 RS22295
gene id: 1145276:T479_RS22295
uniprot id: A0A806LZK3
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1145276:T479 RS14115
gene id: 1145276:T479_RS14115
uniprot id: A0A806LQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1145276:T479 RS08915
gene id: 1145276:T479_RS08915
uniprot id: A0A806LIQ3
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS05050
gene id: 1145276:T479_RS05050
uniprot id: A0A806LGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1145276:T479 RS07255
gene id: 1145276:T479_RS07255
uniprot id: A0A806LHT8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS03845
gene id: 1145276:T479_RS03845
uniprot id: A0A806LMD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS14860
gene id: 1145276:T479_RS14860
uniprot id: A0A806LK52
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1145276:T479 RS21885
gene id: 1145276:T479_RS21885
uniprot id: A0A806LV45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1145276:T479 RS21185
gene id: 1145276:T479_RS21185
uniprot id: A0A806LN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS10130
gene id: 1145276:T479_RS10130
uniprot id: A0A806LHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1145276:T479 RS05940
gene id: 1145276:T479_RS05940
uniprot id: A0A806LLU9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1145276:T479 RS22485
gene id: 1145276:T479_RS22485
uniprot id: A0A806LV59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1145276:T479 RS07980
gene id: 1145276:T479_RS07980
uniprot id: A0A806LGM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1145276:T479 RS16380
gene id: 1145276:T479_RS16380
uniprot id: A0A806LUV9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1145276:T479 RS04460
gene id: 1145276:T479_RS04460
uniprot id: A0A806LNY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1145276:T479 RS12990
gene id: 1145276:T479_RS12990
uniprot id: A0A806LRU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1145276:T479 RS12980
gene id: 1145276:T479_RS12980
uniprot id: A0A806LJ30
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS16680
gene id: 1145276:T479_RS16680
uniprot id: A0A806LWK2
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04345
gene id: 1145276:T479_RS04345
uniprot id: A0A806LQC1
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS20945
gene id: 1145276:T479_RS20945
uniprot id: A0A806LUC2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1145276:T479 RS18050
gene id: 1145276:T479_RS18050
uniprot id: A0A806LN21
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1145276:T479 RS12830
gene id: 1145276:T479_RS12830
uniprot id: A0A806LLG6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS13155
gene id: 1145276:T479_RS13155
uniprot id: A0A806LQ80
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS04805
gene id: 1145276:T479_RS04805
uniprot id: A0A806LL90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1145276:T479 RS16300
gene id: 1145276:T479_RS16300
uniprot id: A0A806LRX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1145276:T479 RS06705
gene id: 1145276:T479_RS06705
uniprot id: A0A806LNV1
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1145276:T479 RS21910
gene id: 1145276:T479_RS21910
uniprot id: A0A806LWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS06485
gene id: 1145276:T479_RS06485
uniprot id: A0A806LG71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS18795
gene id: 1145276:T479_RS18795
uniprot id: A0A806LM22
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1145276:T479 RS01105
gene id: 1145276:T479_RS01105
uniprot id: A0A806LD74
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS02380
gene id: 1145276:T479_RS02380
uniprot id: A0A806LPC3
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

1145276:T479 RS19915
gene id: 1145276:T479_RS19915
uniprot id: A0A806LVC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

1145276:T479 RS17670
gene id: 1145276:T479_RS17670
uniprot id: A0A806LLK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1145276:T479 RS05720
gene id: 1145276:T479_RS05720
uniprot id: A0A806LYF8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the C-terminal section; belongs to the NRP synthetase family.

1145276:T479 RS20780
gene id: 1145276:T479_RS20780
uniprot id: A0A806LU85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS21820
gene id: 1145276:T479_RS21820
uniprot id: A0A806LNK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1145276:T479 RS01170
gene id: 1145276:T479_RS01170
uniprot id: A0A806LL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS02840
gene id: 1145276:T479_RS02840
uniprot id: A0A806LLW0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1145276:T479 RS10225
gene id: 1145276:T479_RS10225
uniprot id: A0A806LNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1145276:T479 RS07115
gene id: 1145276:T479_RS07115
uniprot id: A0A806LGG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1145276:T479 RS10460
gene id: 1145276:T479_RS10460
uniprot id: A0A806LTJ9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS03080
gene id: 1145276:T479_RS03080
uniprot id: A0A806LLY6
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS05290
gene id: 1145276:T479_RS05290
uniprot id: A0A806LI18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1145276:T479 RS14555
gene id: 1145276:T479_RS14555
uniprot id: A0A806LRS6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1145276:T479 RS07380
gene id: 1145276:T479_RS07380
uniprot id: A0A806LQD4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1145276:T479 RS20940
gene id: 1145276:T479_RS20940
uniprot id: A0A806LPH6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1145276:T479 RS14830
gene id: 1145276:T479_RS14830
uniprot id: A0A806LR55
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

1145276:T479 RS20710
gene id: 1145276:T479_RS20710
uniprot id: A0A806LMZ9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1145276:T479 RS06765
gene id: 1145276:T479_RS06765
uniprot id: A0A806LHM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1145276:T479 RS20555
gene id: 1145276:T479_RS20555
uniprot id: A0A806LQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1145276:T479 RS01395
gene id: 1145276:T479_RS01395
uniprot id: A0A806LG40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS06015
gene id: 1145276:T479_RS06015
uniprot id: A0A806LPR3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1145276:T479 RS17960
gene id: 1145276:T479_RS17960
uniprot id: A0A806LX56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS10175
gene id: 1145276:T479_RS10175
uniprot id: A0A806LNX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1145276:T479 RS07850
gene id: 1145276:T479_RS07850
uniprot id: A0A806LS62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS03760
gene id: 1145276:T479_RS03760
uniprot id: A0A806LES6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS22660
gene id: 1145276:T479_RS22660
uniprot id: A0A806LZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1145276:T479 RS02785
gene id: 1145276:T479_RS02785
uniprot id: A0A806LFF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1145276:T479 RS01050
gene id: 1145276:T479_RS01050
uniprot id: A0A806LD62
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS08980
gene id: 1145276:T479_RS08980
uniprot id: A0A806LSS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS00100
gene id: 1145276:T479_RS00100
uniprot id: A0A806LFI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1145276:T479 RS02720
gene id: 1145276:T479_RS02720
uniprot id: A0A806LGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1145276:T479 RS04060
gene id: 1145276:T479_RS04060
uniprot id: A0A806LKW0
names: Similarity
messages: Belongs to the UPF0223 family.

1145276:T479 RS22050
gene id: 1145276:T479_RS22050
uniprot id: A0A806LNM9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1145276:T479 RS05545
gene id: 1145276:T479_RS05545
uniprot id: A0A806LFS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS00705
gene id: 1145276:T479_RS00705
uniprot id: A0A806LK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS17815
gene id: 1145276:T479_RS17815
uniprot id: A0A806LLI9
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1145276:T479 RS03040
gene id: 1145276:T479_RS03040
uniprot id: A0A806LFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1145276:T479 RS04830
gene id: 1145276:T479_RS04830
uniprot id: A0A806LFA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1145276:T479 RS06445
gene id: 1145276:T479_RS06445
uniprot id: A0A806LMU0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04625
gene id: 1145276:T479_RS04625
uniprot id: A0A806LHP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1145276:T479 RS08350
gene id: 1145276:T479_RS08350
uniprot id: A0A806LN19
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS22020
gene id: 1145276:T479_RS22020
uniprot id: A0A806LQ04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS15950
gene id: 1145276:T479_RS15950
uniprot id: A0A806LWM6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1145276:T479 RS05445
gene id: 1145276:T479_RS05445
uniprot id: A0A806LPH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1145276:T479 RS03610
gene id: 1145276:T479_RS03610
uniprot id: A0A806LEP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS14270
gene id: 1145276:T479_RS14270
uniprot id: A0A806LQV5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1145276:T479 RS02645
gene id: 1145276:T479_RS02645
uniprot id: A0A806LE79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1145276:T479 RS16850
gene id: 1145276:T479_RS16850
uniprot id: A0A806LNH2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1145276:T479 RS15740
gene id: 1145276:T479_RS15740
uniprot id: A0A806LRP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1145276:T479 RS21740
gene id: 1145276:T479_RS21740
uniprot id: A0A806LNH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS17650
gene id: 1145276:T479_RS17650
uniprot id: A0A806LU82
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1145276:T479 RS09145
gene id: 1145276:T479_RS09145
uniprot id: A0A806LP50
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS09585
gene id: 1145276:T479_RS09585
uniprot id: A0A806LQ94
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1145276:T479 RS08545
gene id: 1145276:T479_RS08545
uniprot id: A0A806LR03
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS13055
gene id: 1145276:T479_RS13055
uniprot id: A0A806LQ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1145276:T479 RS12955
gene id: 1145276:T479_RS12955
uniprot id: A0A806LQ36
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS07455
gene id: 1145276:T479_RS07455
uniprot id: A0A806LHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS07925
gene id: 1145276:T479_RS07925
uniprot id: A0A806LQP2
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS08530
gene id: 1145276:T479_RS08530
uniprot id: A0A806LH82
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1145276:T479 RS11055
gene id: 1145276:T479_RS11055
uniprot id: A0A806LTW3
names: Similarity
messages: Belongs to the peptidase S66 family.

1145276:T479 RS08310
gene id: 1145276:T479_RS08310
uniprot id: A0A806LNR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1145276:T479 RS16740
gene id: 1145276:T479_RS16740
uniprot id: A0A806LV31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1145276:T479 RS21790
gene id: 1145276:T479_RS21790
uniprot id: A0A806LNH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS08845
gene id: 1145276:T479_RS08845
uniprot id: A0A806LPX9
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS19885
gene id: 1145276:T479_RS19885
uniprot id: A0A806LMM9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1145276:T479 RS03635
gene id: 1145276:T479_RS03635
uniprot id: A0A806LH66
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1145276:T479 RS09270
gene id: 1145276:T479_RS09270
uniprot id: A0A806LHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1145276:T479 RS11740
gene id: 1145276:T479_RS11740
uniprot id: A0A806LIQ7
names: Similarity
messages: Belongs to the peptidase S14 family.

1145276:T479 RS15175
gene id: 1145276:T479_RS15175
uniprot id: A0A806LRF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS10290
gene id: 1145276:T479_RS10290
uniprot id: A0A806LI02
names: Similarity
messages: Belongs to the peptidase S9C family.

1145276:T479 RS05810
gene id: 1145276:T479_RS05810
uniprot id: A0A806LNF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1145276:T479 RS02455
gene id: 1145276:T479_RS02455
uniprot id: A0A806LGL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BioW family.
messages: Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
messages: Homodimer.

1145276:T479 RS22465
gene id: 1145276:T479_RS22465
uniprot id: A0A806LR39
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS13115
gene id: 1145276:T479_RS13115
uniprot id: A0A806LJB1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1145276:T479 RS05890
gene id: 1145276:T479_RS05890
uniprot id: A0A806LR42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1145276:T479 RS04145
gene id: 1145276:T479_RS04145
uniprot id: A0A806LEX1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1145276:T479 RS08405
gene id: 1145276:T479_RS08405
uniprot id: A0A806LN29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS20320
gene id: 1145276:T479_RS20320
uniprot id: A0A806LMW0
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS03480
gene id: 1145276:T479_RS03480
uniprot id: A0A806LNF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1145276:T479 RS03120
gene id: 1145276:T479_RS03120
uniprot id: A0A806LEB3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1145276:T479 RS22520
gene id: 1145276:T479_RS22520
uniprot id: A0A806LWN0
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS16990
gene id: 1145276:T479_RS16990
uniprot id: A0A806LV75
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1145276:T479 RS21505
gene id: 1145276:T479_RS21505
uniprot id: A0A806LNH0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS02180
gene id: 1145276:T479_RS02180
uniprot id: A0A806LKQ6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1145276:T479 RS18435
gene id: 1145276:T479_RS18435
uniprot id: A0A806LXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1145276:T479 RS07675
gene id: 1145276:T479_RS07675
uniprot id: A0A806LMR0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS17660
gene id: 1145276:T479_RS17660
uniprot id: A0A806LMT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1145276:T479 RS14140
gene id: 1145276:T479_RS14140
uniprot id: A0A806LRI0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1145276:T479 RS17110
gene id: 1145276:T479_RS17110
uniprot id: A0A806LNM8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1145276:T479 RS14655
gene id: 1145276:T479_RS14655
uniprot id: A0A806LRU2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1145276:T479 RS01230
gene id: 1145276:T479_RS01230
uniprot id: A0A806LJC5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS09915
gene id: 1145276:T479_RS09915
uniprot id: A0A806LNV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1145276:T479 RS05850
gene id: 1145276:T479_RS05850
uniprot id: A0A806LPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS17870
gene id: 1145276:T479_RS17870
uniprot id: A0A806LNW4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1145276:T479 RS13070
gene id: 1145276:T479_RS13070
uniprot id: A0A806LJA1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1145276:T479 RS17955
gene id: 1145276:T479_RS17955
uniprot id: A0A806LLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1145276:T479 RS14940
gene id: 1145276:T479_RS14940
uniprot id: A0A806LKC1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1145276:T479 RS07275
gene id: 1145276:T479_RS07275
uniprot id: A0A806LN77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1145276:T479 RS18780
gene id: 1145276:T479_RS18780
uniprot id: A0A806LXN3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1145276:T479 RS10380
gene id: 1145276:T479_RS10380
uniprot id: A0A806LKH5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1145276:T479 RS16785
gene id: 1145276:T479_RS16785
uniprot id: A0A806LST1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1145276:T479 RS06125
gene id: 1145276:T479_RS06125
uniprot id: A0A806LIE9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1145276:T479 RS10030
gene id: 1145276:T479_RS10030
uniprot id: A0A806LTA1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS22480
gene id: 1145276:T479_RS22480
uniprot id: A0A806LQ97
names: Similarity
messages: Belongs to the AAA ATPase family.

1145276:T479 RS14015
gene id: 1145276:T479_RS14015
uniprot id: A0A806LQQ4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

1145276:T479 RS21180
gene id: 1145276:T479_RS21180
uniprot id: A0A806LX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS05420
gene id: 1145276:T479_RS05420
uniprot id: A0A806LH08
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1145276:T479 RS17665
gene id: 1145276:T479_RS17665
uniprot id: A0A806LSJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1145276:T479 RS08955
gene id: 1145276:T479_RS08955
uniprot id: A0A806LNF5
names: Similarity
messages: Belongs to the peptidase S58 family.

1145276:T479 RS18940
gene id: 1145276:T479_RS18940
uniprot id: A0A806LM50
names: Similarity
messages: Belongs to the catalase family.

1145276:T479 RS17700
gene id: 1145276:T479_RS17700
uniprot id: A0A806LSL7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1145276:T479 RS14875
gene id: 1145276:T479_RS14875
uniprot id: A0A806LR81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1145276:T479 RS17520
gene id: 1145276:T479_RS17520
uniprot id: A0A806LT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1145276:T479 RS15155
gene id: 1145276:T479_RS15155
uniprot id: A0A806LUE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS13990
gene id: 1145276:T479_RS13990
uniprot id: A0A806LJN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1145276:T479 RS08975
gene id: 1145276:T479_RS08975
uniprot id: A0A806LHE4
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1145276:T479 RS13110
gene id: 1145276:T479_RS13110
uniprot id: A0A806LQ70
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1145276:T479 RS03110
gene id: 1145276:T479_RS03110
uniprot id: A0A806LL62
names: Similarity
messages: Belongs to the FlgM family.

1145276:T479 RS10970
gene id: 1145276:T479_RS10970
uniprot id: A0A806LPB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS14225
gene id: 1145276:T479_RS14225
uniprot id: A0A806LJZ2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1145276:T479 RS18555
gene id: 1145276:T479_RS18555
uniprot id: A0A806LLX0
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1145276:T479 RS00275
gene id: 1145276:T479_RS00275
uniprot id: A0A806LFL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1145276:T479 RS10750
gene id: 1145276:T479_RS10750
uniprot id: A0A806LI87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1145276:T479 RS05460
gene id: 1145276:T479_RS05460
uniprot id: A0A806LNA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1145276:T479 RS16620
gene id: 1145276:T479_RS16620
uniprot id: A0A806LL45
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS05685
gene id: 1145276:T479_RS05685
uniprot id: A0A806LR07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS13270
gene id: 1145276:T479_RS13270
uniprot id: A0A806LUV3
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1145276:T479 RS13170
gene id: 1145276:T479_RS13170
uniprot id: A0A806LQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1145276:T479 RS07620
gene id: 1145276:T479_RS07620
uniprot id: A0A806LMQ3
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS13340
gene id: 1145276:T479_RS13340
uniprot id: A0A806LLS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1145276:T479 RS07975
gene id: 1145276:T479_RS07975
uniprot id: A0A806LQQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1145276:T479 RS00730
gene id: 1145276:T479_RS00730
uniprot id: A0A806LJ49
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1145276:T479 RS20820
gene id: 1145276:T479_RS20820
uniprot id: A0A806LQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1145276:T479 RS04655
gene id: 1145276:T479_RS04655
uniprot id: A0A806LQH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1145276:T479 RS01985
gene id: 1145276:T479_RS01985
uniprot id: A0A806LDN7
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS04265
gene id: 1145276:T479_RS04265
uniprot id: A0A806LMM2
names: Similarity
messages: Belongs to the peptidase S16 family.

1145276:T479 RS04465
gene id: 1145276:T479_RS04465
uniprot id: A0A806LF31
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1145276:T479 RS14560
gene id: 1145276:T479_RS14560
uniprot id: A0A806LU31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1145276:T479 RS18460
gene id: 1145276:T479_RS18460
uniprot id: A0A806LP48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1145276:T479 RS14930
gene id: 1145276:T479_RS14930
uniprot id: A0A806LLK8
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1145276:T479 RS20445
gene id: 1145276:T479_RS20445
uniprot id: A0A806LWR8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1145276:T479 RS07570
gene id: 1145276:T479_RS07570
uniprot id: A0A806LMP5
names: Similarity
messages: Belongs to the LOG family.

1145276:T479 RS17685
gene id: 1145276:T479_RS17685
uniprot id: A0A806LVG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1145276:T479 RS09000
gene id: 1145276:T479_RS09000
uniprot id: A0A806LJW4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS02120
gene id: 1145276:T479_RS02120
uniprot id: A0A806LDW7
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1145276:T479 RS20690
gene id: 1145276:T479_RS20690
uniprot id: A0A806LN25
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1145276:T479 RS21230
gene id: 1145276:T479_RS21230
uniprot id: A0A806LYZ4
names: Cofactor
messages: Binds 1 FAD per subunit.

1145276:T479 RS07465
gene id: 1145276:T479_RS07465
uniprot id: A0A806LGQ4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1145276:T479 RS03995
gene id: 1145276:T479_RS03995
uniprot id: A0A806LEU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1145276:T479 RS06650
gene id: 1145276:T479_RS06650
uniprot id: A0A806LNU0
names: Similarity
messages: Belongs to the ferrochelatase family.

1145276:T479 RS16770
gene id: 1145276:T479_RS16770
uniprot id: A0A806LS50
names: Similarity
messages: Belongs to the UPF0173 family.

1145276:T479 RS20835
gene id: 1145276:T479_RS20835
uniprot id: A0A806LU94
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS12510
gene id: 1145276:T479_RS12510
uniprot id: A0A806LSV5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1145276:T479 RS20620
gene id: 1145276:T479_RS20620
uniprot id: A0A806LU55
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

1145276:T479 RS14975
gene id: 1145276:T479_RS14975
uniprot id: A0A806LRA5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1145276:T479 RS08525
gene id: 1145276:T479_RS08525
uniprot id: A0A806LN46
names: Similarity
messages: Belongs to the peptidase M20A family.

1145276:T479 RS21750
gene id: 1145276:T479_RS21750
uniprot id: A0A806LW76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1145276:T479 RS04300
gene id: 1145276:T479_RS04300
uniprot id: A0A806LNV6
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS10180
gene id: 1145276:T479_RS10180
uniprot id: A0A806LHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1145276:T479 RS03615
gene id: 1145276:T479_RS03615
uniprot id: A0A806LPY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS20130
gene id: 1145276:T479_RS20130
uniprot id: A0A806LPZ2
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS10910
gene id: 1145276:T479_RS10910
uniprot id: A0A806LIC5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1145276:T479 RS12730
gene id: 1145276:T479_RS12730
uniprot id: A0A806LY58
names: Subcellular Location Annotation
messages: Secreted

1145276:T479 RS12415
gene id: 1145276:T479_RS12415
uniprot id: A0A806LL95
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS21930
gene id: 1145276:T479_RS21930
uniprot id: A0A806LNM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1145276:T479 RS09170
gene id: 1145276:T479_RS09170
uniprot id: A0A806LNJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1145276:T479 RS18610
gene id: 1145276:T479_RS18610
uniprot id: A0A806LUP0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS02725
gene id: 1145276:T479_RS02725
uniprot id: A0A806LLT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1145276:T479 RS16360
gene id: 1145276:T479_RS16360
uniprot id: A0A806LRY1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1145276:T479 RS12615
gene id: 1145276:T479_RS12615
uniprot id: A0A806LJ17
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1145276:T479 RS02925
gene id: 1145276:T479_RS02925
uniprot id: A0A806LPK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1145276:T479 RS09165
gene id: 1145276:T479_RS09165
uniprot id: A0A806LQ35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1145276:T479 RS17725
gene id: 1145276:T479_RS17725
uniprot id: A0A806LT72
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1145276:T479 RS02810
gene id: 1145276:T479_RS02810
uniprot id: A0A806LL25
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS21265
gene id: 1145276:T479_RS21265
uniprot id: A0A806LPP0
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS22060
gene id: 1145276:T479_RS22060
uniprot id: A0A806LWD7
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.

1145276:T479 RS01770
gene id: 1145276:T479_RS01770
uniprot id: A0A806LJM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1145276:T479 RS20120
gene id: 1145276:T479_RS20120
uniprot id: A0A806LWL7
names: Cofactor
messages: Binds 1 FAD per subunit.

1145276:T479 RS05770
gene id: 1145276:T479_RS05770
uniprot id: A0A806LLS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1145276:T479 RS08565
gene id: 1145276:T479_RS08565
uniprot id: A0A806LN81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS22170
gene id: 1145276:T479_RS22170
uniprot id: A0A806LWF9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1145276:T479 RS07525
gene id: 1145276:T479_RS07525
uniprot id: A0A806LHZ7
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

1145276:T479 RS22330
gene id: 1145276:T479_RS22330
uniprot id: A0A806LQ67
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS18020
gene id: 1145276:T479_RS18020
uniprot id: A0A806LTC9
names: Similarity
messages: Belongs to the arginase family.

1145276:T479 RS22260
gene id: 1145276:T479_RS22260
uniprot id: A0A806LNS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS19570
gene id: 1145276:T479_RS19570
uniprot id: A0A806LTJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1145276:T479 RS15195
gene id: 1145276:T479_RS15195
uniprot id: A0A806LVX4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS21395
gene id: 1145276:T479_RS21395
uniprot id: A0A806LUL1
names: Similarity
messages: Belongs to the IucA/IucC family.

1145276:T479 RS04340
gene id: 1145276:T479_RS04340
uniprot id: A0A806LF37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1145276:T479 RS17120
gene id: 1145276:T479_RS17120
uniprot id: A0A806LU22
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS18400
gene id: 1145276:T479_RS18400
uniprot id: A0A806LVR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS02460
gene id: 1145276:T479_RS02460
uniprot id: A0A806LLN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1145276:T479 RS05215
gene id: 1145276:T479_RS05215
uniprot id: A0A806LFL9
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1145276:T479 RS10605
gene id: 1145276:T479_RS10605
uniprot id: A0A806LI14
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1145276:T479 RS15230
gene id: 1145276:T479_RS15230
uniprot id: A0A806LRG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1145276:T479 RS21745
gene id: 1145276:T479_RS21745
uniprot id: A0A806LQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1145276:T479 RS10095
gene id: 1145276:T479_RS10095
uniprot id: A0A806LRU4
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS02205
gene id: 1145276:T479_RS02205
uniprot id: A0A806LJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1145276:T479 RS11405
gene id: 1145276:T479_RS11405
uniprot id: A0A806LPJ1
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS19420
gene id: 1145276:T479_RS19420
uniprot id: A0A806LNP5
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1145276:T479 RS16415
gene id: 1145276:T479_RS16415
uniprot id: A0A806LL05
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS07790
gene id: 1145276:T479_RS07790
uniprot id: A0A806LGV8
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS12550
gene id: 1145276:T479_RS12550
uniprot id: A0A806LPW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS07165
gene id: 1145276:T479_RS07165
uniprot id: A0A806LGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1145276:T479 RS05980
gene id: 1145276:T479_RS05980
uniprot id: A0A806LLX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1145276:T479 RS09030
gene id: 1145276:T479_RS09030
uniprot id: A0A806LST2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1145276:T479 RS22100
gene id: 1145276:T479_RS22100
uniprot id: A0A806LNN9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1145276:T479 RS19760
gene id: 1145276:T479_RS19760
uniprot id: A0A806LPS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1145276:T479 RS19440
gene id: 1145276:T479_RS19440
uniprot id: A0A806LU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS20100
gene id: 1145276:T479_RS20100
uniprot id: A0A806LTW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS18430
gene id: 1145276:T479_RS18430
uniprot id: A0A806LLY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1145276:T479 RS19350
gene id: 1145276:T479_RS19350
uniprot id: A0A806LPJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0295 family.
messages: Cell membrane

1145276:T479 RS07390
gene id: 1145276:T479_RS07390
uniprot id: A0A806LJ20
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1145276:T479 RS18380
gene id: 1145276:T479_RS18380
uniprot id: A0A806LSW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1145276:T479 RS17080
gene id: 1145276:T479_RS17080
uniprot id: A0A806LLD7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS06325
gene id: 1145276:T479_RS06325
uniprot id: A0A806LRC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS08850
gene id: 1145276:T479_RS08850
uniprot id: A0A806LNC6
names: Similarity
messages: Belongs to the peptidase S51 family.

1145276:T479 RS20530
gene id: 1145276:T479_RS20530
uniprot id: A0A806LMZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1145276:T479 RS18165
gene id: 1145276:T479_RS18165
uniprot id: A0A806LSV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1145276:T479 RS00355
gene id: 1145276:T479_RS00355
uniprot id: A0A806LNB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1145276:T479 RS00610
gene id: 1145276:T479_RS00610
uniprot id: A0A806LKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS04620
gene id: 1145276:T479_RS04620
uniprot id: A0A806LF61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1145276:T479 RS07265
gene id: 1145276:T479_RS07265
uniprot id: A0A806LGL4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1145276:T479 RS13465
gene id: 1145276:T479_RS13465
uniprot id: A0A806LUZ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1145276:T479 RS16835
gene id: 1145276:T479_RS16835
uniprot id: A0A806LSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1145276:T479 RS14945
gene id: 1145276:T479_RS14945
uniprot id: A0A806LVS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1145276:T479 RS04870
gene id: 1145276:T479_RS04870
uniprot id: A0A806LM33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1145276:T479 RS14985
gene id: 1145276:T479_RS14985
uniprot id: A0A806LR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS06055
gene id: 1145276:T479_RS06055
uniprot id: A0A806LR77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1145276:T479 RS10500
gene id: 1145276:T479_RS10500
uniprot id: A0A806LJG0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS01955
gene id: 1145276:T479_RS01955
uniprot id: A0A806LEY9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS09160
gene id: 1145276:T479_RS09160
uniprot id: A0A806LJZ3
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1145276:T479 RS14105
gene id: 1145276:T479_RS14105
uniprot id: A0A806LM64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1145276:T479 RS14205
gene id: 1145276:T479_RS14205
uniprot id: A0A806LSI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1145276:T479 RS01830
gene id: 1145276:T479_RS01830
uniprot id: A0A806LKI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1145276:T479 RS21810
gene id: 1145276:T479_RS21810
uniprot id: A0A806LPW5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1145276:T479 RS21860
gene id: 1145276:T479_RS21860
uniprot id: A0A806LUS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1145276:T479 RS04320
gene id: 1145276:T479_RS04320
uniprot id: A0A806LMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1145276:T479 RS16540
gene id: 1145276:T479_RS16540
uniprot id: A0A806LNB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS09005
gene id: 1145276:T479_RS09005
uniprot id: A0A806LQ07
names: Similarity
messages: Belongs to the peptidase S66 family.

1145276:T479 RS20300
gene id: 1145276:T479_RS20300
uniprot id: A0A806LVJ6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1145276:T479 RS18490
gene id: 1145276:T479_RS18490
uniprot id: A0A806LXF5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1145276:T479 RS15385
gene id: 1145276:T479_RS15385
uniprot id: A0A806LT61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1145276:T479 RS00810
gene id: 1145276:T479_RS00810
uniprot id: A0A806LD77
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS16535
gene id: 1145276:T479_RS16535
uniprot id: A0A806LKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS13380
gene id: 1145276:T479_RS13380
uniprot id: A0A806LJC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1145276:T479 RS03775
gene id: 1145276:T479_RS03775
uniprot id: A0A806LNL1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1145276:T479 RS03295
gene id: 1145276:T479_RS03295
uniprot id: A0A806LM26
names: Similarity
messages: Belongs to the peptidase S41A family.

1145276:T479 RS08245
gene id: 1145276:T479_RS08245
uniprot id: A0A806LW42
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS01445
gene id: 1145276:T479_RS01445
uniprot id: A0A806LMC3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS19960
gene id: 1145276:T479_RS19960
uniprot id: A0A806LPW0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1145276:T479 RS19890
gene id: 1145276:T479_RS19890
uniprot id: A0A806LYA6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1145276:T479 RS18210
gene id: 1145276:T479_RS18210
uniprot id: A0A806LP21
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1145276:T479 RS03270
gene id: 1145276:T479_RS03270
uniprot id: A0A806LPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1145276:T479 RS12940
gene id: 1145276:T479_RS12940
uniprot id: A0A806LRU0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1145276:T479 RS01850
gene id: 1145276:T479_RS01850
uniprot id: A0A806LLB7
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1145276:T479 RS11410
gene id: 1145276:T479_RS11410
uniprot id: A0A806LJV5
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS00675
gene id: 1145276:T479_RS00675
uniprot id: A0A806LKU1
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS07160
gene id: 1145276:T479_RS07160
uniprot id: A0A806LME1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1145276:T479 RS00815
gene id: 1145276:T479_RS00815
uniprot id: A0A806LNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS19865
gene id: 1145276:T479_RS19865
uniprot id: A0A806LPT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1145276:T479 RS16420
gene id: 1145276:T479_RS16420
uniprot id: A0A806LWF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1145276:T479 RS10275
gene id: 1145276:T479_RS10275
uniprot id: A0A806LP05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS14070
gene id: 1145276:T479_RS14070
uniprot id: A0A806LQR1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1145276:T479 RS20480
gene id: 1145276:T479_RS20480
uniprot id: A0A806LMX8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1145276:T479 RS00305
gene id: 1145276:T479_RS00305
uniprot id: A0A806LNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1145276:T479 RS12890
gene id: 1145276:T479_RS12890
uniprot id: A0A806LQ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1145276:T479 RS12685
gene id: 1145276:T479_RS12685
uniprot id: A0A806LQN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS05150
gene id: 1145276:T479_RS05150
uniprot id: A0A806LLH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1145276:T479 RS04590
gene id: 1145276:T479_RS04590
uniprot id: A0A806LGJ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS04945
gene id: 1145276:T479_RS04945
uniprot id: A0A806LLD8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1145276:T479 RS19965
gene id: 1145276:T479_RS19965
uniprot id: A0A806LVD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1145276:T479 RS10505
gene id: 1145276:T479_RS10505
uniprot id: A0A806LP32
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS08215
gene id: 1145276:T479_RS08215
uniprot id: A0A806LMZ4
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS18950
gene id: 1145276:T479_RS18950
uniprot id: A0A806LUV8
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS00030
gene id: 1145276:T479_RS00030
uniprot id: A0A806LIR2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1145276:T479 RS06770
gene id: 1145276:T479_RS06770
uniprot id: A0A806LM88
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1145276:T479 RS07670
gene id: 1145276:T479_RS07670
uniprot id: A0A806LPA9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS21600
gene id: 1145276:T479_RS21600
uniprot id: A0A806LNI0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS21805
gene id: 1145276:T479_RS21805
uniprot id: A0A806LUR0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1145276:T479 RS17210
gene id: 1145276:T479_RS17210
uniprot id: A0A806LU41
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1145276:T479 RS06340
gene id: 1145276:T479_RS06340
uniprot id: A0A806LMS6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS14245
gene id: 1145276:T479_RS14245
uniprot id: A0A806LJU2
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS07060
gene id: 1145276:T479_RS07060
uniprot id: A0A806LMB9
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1145276:T479 RS06545
gene id: 1145276:T479_RS06545
uniprot id: A0A806LM47
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1145276:T479 RS08315
gene id: 1145276:T479_RS08315
uniprot id: A0A806LQW5
names: Similarity
messages: Belongs to the Dps family.

1145276:T479 RS04700
gene id: 1145276:T479_RS04700
uniprot id: A0A806LFB5
names: Similarity
messages: Belongs to the asp23 family.

1145276:T479 RS18530
gene id: 1145276:T479_RS18530
uniprot id: A0A806LT05
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1145276:T479 RS16385
gene id: 1145276:T479_RS16385
uniprot id: A0A806LKU5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1145276:T479 RS17230
gene id: 1145276:T479_RS17230
uniprot id: A0A806LLG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1145276:T479 RS05105
gene id: 1145276:T479_RS05105
uniprot id: A0A806LGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1145276:T479 RS17540
gene id: 1145276:T479_RS17540
uniprot id: A0A806LNQ9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1145276:T479 RS01750
gene id: 1145276:T479_RS01750
uniprot id: A0A806LY92
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS09630
gene id: 1145276:T479_RS09630
uniprot id: A0A806LK56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS08005
gene id: 1145276:T479_RS08005
uniprot id: A0A806LI93
names: Similarity
messages: Belongs to the PduL family.

1145276:T479 RS19575
gene id: 1145276:T479_RS19575
uniprot id: A0A806LNS8
names: Similarity
messages: Belongs to the peptidase M29 family.

1145276:T479 RS03630
gene id: 1145276:T479_RS03630
uniprot id: A0A806LEL5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1145276:T479 RS04510
gene id: 1145276:T479_RS04510
uniprot id: A0A806LNZ8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS20295
gene id: 1145276:T479_RS20295
uniprot id: A0A806LQ20
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS11870
gene id: 1145276:T479_RS11870
uniprot id: A0A806LPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

1145276:T479 RS08540
gene id: 1145276:T479_RS08540
uniprot id: A0A806LNV3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1145276:T479 RS04375
gene id: 1145276:T479_RS04375
uniprot id: A0A806LL21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1145276:T479 RS02675
gene id: 1145276:T479_RS02675
uniprot id: A0A806LLS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS00315
gene id: 1145276:T479_RS00315
uniprot id: A0A806LLT8
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1145276:T479 RS09080
gene id: 1145276:T479_RS09080
uniprot id: A0A806LHG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS15065
gene id: 1145276:T479_RS15065
uniprot id: A0A806LMN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1145276:T479 RS04490
gene id: 1145276:T479_RS04490
uniprot id: A0A806LL33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

1145276:T479 RS07490
gene id: 1145276:T479_RS07490
uniprot id: A0A806LGF4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1145276:T479 RS16645
gene id: 1145276:T479_RS16645
uniprot id: A0A806LND2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1145276:T479 RS16585
gene id: 1145276:T479_RS16585
uniprot id: A0A806LV00
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1145276:T479 RS00830
gene id: 1145276:T479_RS00830
uniprot id: A0A806LD40
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS18745
gene id: 1145276:T479_RS18745
uniprot id: A0A806LM08
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1145276:T479 RS05300
gene id: 1145276:T479_RS05300
uniprot id: A0A806LLK9
names: Similarity
messages: Belongs to the CpsD/CapB family.

1145276:T479 RS14995
gene id: 1145276:T479_RS14995
uniprot id: A0A806LVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1145276:T479 RS02345
gene id: 1145276:T479_RS02345
uniprot id: A0A806LGI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1145276:T479 RS04850
gene id: 1145276:T479_RS04850
uniprot id: A0A806LGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1145276:T479 RS19490
gene id: 1145276:T479_RS19490
uniprot id: A0A806LW98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1145276:T479 RS20160
gene id: 1145276:T479_RS20160
uniprot id: A0A806LYG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1145276:T479 RS18835
gene id: 1145276:T479_RS18835
uniprot id: A0A806LXP9
names: Similarity
messages: Belongs to the UPF0342 family.

1145276:T479 RS20515
gene id: 1145276:T479_RS20515
uniprot id: A0A806LU36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1145276:T479 RS07225
gene id: 1145276:T479_RS07225
uniprot id: A0A806LN67
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1145276:T479 RS05140
gene id: 1145276:T479_RS05140
uniprot id: A0A806LHZ3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1145276:T479 RS19820
gene id: 1145276:T479_RS19820
uniprot id: A0A806LTP6
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS20150
gene id: 1145276:T479_RS20150
uniprot id: A0A806LTY1
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1145276:T479 RS15820
gene id: 1145276:T479_RS15820
uniprot id: A0A806LN13
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1145276:T479 RS00190
gene id: 1145276:T479_RS00190
uniprot id: A0A806LN85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1145276:T479 RS07550
gene id: 1145276:T479_RS07550
uniprot id: A0A806LQG4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1145276:T479 RS09240
gene id: 1145276:T479_RS09240
uniprot id: A0A806LIW6
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS21095
gene id: 1145276:T479_RS21095
uniprot id: A0A806LPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fosfomycin resistance protein family. FosB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.

1145276:T479 RS13235
gene id: 1145276:T479_RS13235
uniprot id: A0A806LJ89
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1145276:T479 RS04975
gene id: 1145276:T479_RS04975
uniprot id: A0A806LP90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1145276:T479 RS20905
gene id: 1145276:T479_RS20905
uniprot id: A0A806LYT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1145276:T479 RS21845
gene id: 1145276:T479_RS21845
uniprot id: A0A806LQS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1145276:T479 RS04940
gene id: 1145276:T479_RS04940
uniprot id: A0A806LN10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1145276:T479 RS17885
gene id: 1145276:T479_RS17885
uniprot id: A0A806LMX7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1145276:T479 RS22225
gene id: 1145276:T479_RS22225
uniprot id: A0A806LUY9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS00195
gene id: 1145276:T479_RS00195
uniprot id: A0A806LJR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1145276:T479 RS16340
gene id: 1145276:T479_RS16340
uniprot id: A0A806LN76
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1145276:T479 RS08735
gene id: 1145276:T479_RS08735
uniprot id: A0A806LPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1145276:T479 RS06745
gene id: 1145276:T479_RS06745
uniprot id: A0A806LG92
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1145276:T479 RS01855
gene id: 1145276:T479_RS01855
uniprot id: A0A806LJM8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1145276:T479 RS18470
gene id: 1145276:T479_RS18470
uniprot id: A0A806LSZ7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1145276:T479 RS07630
gene id: 1145276:T479_RS07630
uniprot id: A0A806LMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1145276:T479 RS10780
gene id: 1145276:T479_RS10780
uniprot id: A0A806LKN8
names: Similarity
messages: Belongs to the DinB family.

1145276:T479 RS15810
gene id: 1145276:T479_RS15810
uniprot id: A0A806LUP1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1145276:T479 RS08020
gene id: 1145276:T479_RS08020
uniprot id: A0A806LS95
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1145276:T479 RS12875
gene id: 1145276:T479_RS12875
uniprot id: A0A806LJ12
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1145276:T479 RS10965
gene id: 1145276:T479_RS10965
uniprot id: A0A806LJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS01995
gene id: 1145276:T479_RS01995
uniprot id: A0A806LLE5
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS10320
gene id: 1145276:T479_RS10320
uniprot id: A0A806LHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1145276:T479 RS14090
gene id: 1145276:T479_RS14090
uniprot id: A0A806LRG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1145276:T479 RS13530
gene id: 1145276:T479_RS13530
uniprot id: A0A806LJF3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1145276:T479 RS01610
gene id: 1145276:T479_RS01610
uniprot id: A0A806LDK4
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1145276:T479 RS02775
gene id: 1145276:T479_RS02775
uniprot id: A0A806LLU3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1145276:T479 RS22040
gene id: 1145276:T479_RS22040
uniprot id: A0A806LV77
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1145276:T479 RS17690
gene id: 1145276:T479_RS17690
uniprot id: A0A806LLG4
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

1145276:T479 RS10140
gene id: 1145276:T479_RS10140
uniprot id: A0A806LPJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1145276:T479 RS08585
gene id: 1145276:T479_RS08585
uniprot id: A0A806LSJ4
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS01070
gene id: 1145276:T479_RS01070
uniprot id: A0A806LEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1145276:T479 RS04405
gene id: 1145276:T479_RS04405
uniprot id: A0A806LNX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1145276:T479 RS15180
gene id: 1145276:T479_RS15180
uniprot id: A0A806LLR1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1145276:T479 RS16400
gene id: 1145276:T479_RS16400
uniprot id: A0A806LS03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1145276:T479 RS04050
gene id: 1145276:T479_RS04050
uniprot id: A0A806LHD4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1145276:T479 RS10285
gene id: 1145276:T479_RS10285
uniprot id: A0A806LNZ4
names: Similarity
messages: Belongs to the DapA family.

1145276:T479 RS14095
gene id: 1145276:T479_RS14095
uniprot id: A0A806LTT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1145276:T479 RS21355
gene id: 1145276:T479_RS21355
uniprot id: A0A806LUK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1145276:T479 RS21980
gene id: 1145276:T479_RS21980
uniprot id: A0A806LNN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1145276:T479 RS07210
gene id: 1145276:T479_RS07210
uniprot id: A0A806LMF2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1145276:T479 RS15305
gene id: 1145276:T479_RS15305
uniprot id: A0A806LKK1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1145276:T479 RS06695
gene id: 1145276:T479_RS06695
uniprot id: A0A806LG84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1145276:T479 RS21120
gene id: 1145276:T479_RS21120
uniprot id: A0A806LX48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1145276:T479 RS13075
gene id: 1145276:T479_RS13075
uniprot id: A0A806LUQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS02500
gene id: 1145276:T479_RS02500
uniprot id: A0A806LE49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1145276:T479 RS06670
gene id: 1145276:T479_RS06670
uniprot id: A0A806LM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS04235
gene id: 1145276:T479_RS04235
uniprot id: A0A806LF18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

1145276:T479 RS02670
gene id: 1145276:T479_RS02670
uniprot id: A0A806LGP9
names: Similarity
messages: Belongs to the UPF0340 family.

1145276:T479 RS16910
gene id: 1145276:T479_RS16910
uniprot id: A0A806LSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1145276:T479 RS09715
gene id: 1145276:T479_RS09715
uniprot id: A0A806LNP9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS21765
gene id: 1145276:T479_RS21765
uniprot id: A0A806LUQ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1145276:T479 RS00630
gene id: 1145276:T479_RS00630
uniprot id: A0A806LD46
names: Similarity
messages: Belongs to the EamA transporter family.

1145276:T479 RS00085
gene id: 1145276:T479_RS00085
uniprot id: A0A806LJQ2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1145276:T479 RS02415
gene id: 1145276:T479_RS02415
uniprot id: A0A806LK01
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1145276:T479 RS07460
gene id: 1145276:T479_RS07460
uniprot id: A0A806LMK6
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1145276:T479 RS01835
gene id: 1145276:T479_RS01835
uniprot id: A0A806LMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1145276:T479 RS03460
gene id: 1145276:T479_RS03460
uniprot id: A0A806LKI4
names: Similarity
messages: Belongs to the UPF0738 family.

1145276:T479 RS10935
gene id: 1145276:T479_RS10935
uniprot id: A0A806LI83
names: Similarity
messages: Belongs to the peptidase S41A family.

1145276:T479 RS10725
gene id: 1145276:T479_RS10725
uniprot id: A0A806LQS3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS00125
gene id: 1145276:T479_RS00125
uniprot id: A0A806LCV6
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04065
gene id: 1145276:T479_RS04065
uniprot id: A0A806LG34
names: Similarity
messages: Belongs to the UPF0637 family.

1145276:T479 RS01920
gene id: 1145276:T479_RS01920
uniprot id: A0A806LP23
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1145276:T479 RS22635
gene id: 1145276:T479_RS22635
uniprot id: A0A806LWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ParB family.
messages: Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
messages: nucleoid

1145276:T479 RS17245
gene id: 1145276:T479_RS17245
uniprot id: A0A806LVC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1145276:T479 RS02395
gene id: 1145276:T479_RS02395
uniprot id: A0A806LDY6
names: Similarity
messages: Belongs to the UPF0741 family.

1145276:T479 RS13150
gene id: 1145276:T479_RS13150
uniprot id: A0A806LKL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1145276:T479 RS03435
gene id: 1145276:T479_RS03435
uniprot id: A0A806LEH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1145276:T479 RS21990
gene id: 1145276:T479_RS21990
uniprot id: A0A806LV65
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1145276:T479 RS00905
gene id: 1145276:T479_RS00905
uniprot id: A0A806LJ98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS03440
gene id: 1145276:T479_RS03440
uniprot id: A0A806LH33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

1145276:T479 RS18510
gene id: 1145276:T479_RS18510
uniprot id: A0A806LP58
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1145276:T479 RS05135
gene id: 1145276:T479_RS05135
uniprot id: A0A806LFH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1145276:T479 RS04150
gene id: 1145276:T479_RS04150
uniprot id: A0A806LHF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 1 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1145276:T479 RS03070
gene id: 1145276:T479_RS03070
uniprot id: A0A806LEA4
names: Similarity
messages: Belongs to the IMPACT family.

1145276:T479 RS21915
gene id: 1145276:T479_RS21915
uniprot id: A0A806LUT1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS15135
gene id: 1145276:T479_RS15135
uniprot id: A0A806LRC3
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1145276:T479 RS17950
gene id: 1145276:T479_RS17950
uniprot id: A0A806LSQ2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1145276:T479 RS04040
gene id: 1145276:T479_RS04040
uniprot id: A0A806LNQ0
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS20470
gene id: 1145276:T479_RS20470
uniprot id: A0A806LP88
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1145276:T479 RS14345
gene id: 1145276:T479_RS14345
uniprot id: A0A806LRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1145276:T479 RS15845
gene id: 1145276:T479_RS15845
uniprot id: A0A806LKT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds a copper B center.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Heme A3.
messages: Membrane

1145276:T479 RS21115
gene id: 1145276:T479_RS21115
uniprot id: A0A806LUT9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1145276:T479 RS10930
gene id: 1145276:T479_RS10930
uniprot id: A0A806LS96
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1145276:T479 RS03670
gene id: 1145276:T479_RS03670
uniprot id: A0A806LPZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1145276:T479 RS16295
gene id: 1145276:T479_RS16295
uniprot id: A0A806LM74
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1145276:T479 RS00010
gene id: 1145276:T479_RS00010
uniprot id: A0A806LLP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1145276:T479 RS19455
gene id: 1145276:T479_RS19455
uniprot id: A0A806LPK9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS10160
gene id: 1145276:T479_RS10160
uniprot id: A0A806LQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS12765
gene id: 1145276:T479_RS12765
uniprot id: A0A806LQP6
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS15725
gene id: 1145276:T479_RS15725
uniprot id: A0A806LTB9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1145276:T479 RS08355
gene id: 1145276:T479_RS08355
uniprot id: A0A806LH54
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS19790
gene id: 1145276:T479_RS19790
uniprot id: A0A806LY89
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS05380
gene id: 1145276:T479_RS05380
uniprot id: A0A806LFP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS08015
gene id: 1145276:T479_RS08015
uniprot id: A0A806LH04
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1145276:T479 RS03225
gene id: 1145276:T479_RS03225
uniprot id: A0A806LPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1145276:T479 RS06730
gene id: 1145276:T479_RS06730
uniprot id: A0A806LRK9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1145276:T479 RS10625
gene id: 1145276:T479_RS10625
uniprot id: A0A806LJH6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1145276:T479 RS09225
gene id: 1145276:T479_RS09225
uniprot id: A0A806LJZ7
names: Similarity
messages: Belongs to the UPF0111 family.

1145276:T479 RS14350
gene id: 1145276:T479_RS14350
uniprot id: A0A806LTZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1145276:T479 RS15815
gene id: 1145276:T479_RS15815
uniprot id: A0A806LKM7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1145276:T479 RS07875
gene id: 1145276:T479_RS07875
uniprot id: A0A806LPF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1145276:T479 RS21870
gene id: 1145276:T479_RS21870
uniprot id: A0A806LUS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1145276:T479 RS00440
gene id: 1145276:T479_RS00440
uniprot id: A0A806LFN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1145276:T479 RS08985
gene id: 1145276:T479_RS08985
uniprot id: A0A806LP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS07915
gene id: 1145276:T479_RS07915
uniprot id: A0A806LPJ3
names: Similarity
messages: Belongs to the intimin/invasin family.

1145276:T479 RS04920
gene id: 1145276:T479_RS04920
uniprot id: A0A806LM43
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1145276:T479 RS15070
gene id: 1145276:T479_RS15070
uniprot id: A0A806LT01
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS21940
gene id: 1145276:T479_RS21940
uniprot id: A0A806LV55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1145276:T479 RS07995
gene id: 1145276:T479_RS07995
uniprot id: A0A806LPH4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1145276:T479 RS09770
gene id: 1145276:T479_RS09770
uniprot id: A0A806LHK4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1145276:T479 RS12985
gene id: 1145276:T479_RS12985
uniprot id: A0A806LLJ8
names: Subcellular Location Annotation
messages: Cell membrane

1145276:T479 RS18405
gene id: 1145276:T479_RS18405
uniprot id: A0A806LLT6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1145276:T479 RS08950
gene id: 1145276:T479_RS08950
uniprot id: A0A806LQ02
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1145276:T479 RS17090
gene id: 1145276:T479_RS17090
uniprot id: A0A806LSZ5
names: Subcellular Location Annotation
messages: Cytoplasm

1145276:T479 RS15225
gene id: 1145276:T479_RS15225
uniprot id: A0A806LT34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1145276:T479 RS05975
gene id: 1145276:T479_RS05975
uniprot id: A0A806LNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS02665
gene id: 1145276:T479_RS02665
uniprot id: A0A806LE33
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1145276:T479 RS04755
gene id: 1145276:T479_RS04755
uniprot id: A0A806LFC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1145276:T479 RS18395
gene id: 1145276:T479_RS18395
uniprot id: A0A806LTH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1145276:T479 RS00140
gene id: 1145276:T479_RS00140
uniprot id: A0A806LLQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1145276:T479 RS02060
gene id: 1145276:T479_RS02060
uniprot id: A0A806LJS1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1145276:T479 RS03205
gene id: 1145276:T479_RS03205
uniprot id: A0A806LKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1145276:T479 RS18895
gene id: 1145276:T479_RS18895
uniprot id: A0A806LW21
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1145276:T479 RS06070
gene id: 1145276:T479_RS06070
uniprot id: A0A806LYG8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1145276:T479 RS02700
gene id: 1145276:T479_RS02700
uniprot id: A0A806LPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1145276:T479 RS12245
gene id: 1145276:T479_RS12245
uniprot id: A0A806LPR7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS20755
gene id: 1145276:T479_RS20755
uniprot id: A0A806LUM9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1145276:T479 RS15855
gene id: 1145276:T479_RS15855
uniprot id: A0A806LSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

1145276:T479 RS19940
gene id: 1145276:T479_RS19940
uniprot id: A0A806LYB5
names: Similarity
messages: Belongs to the GARS family.

1145276:T479 RS20970
gene id: 1145276:T479_RS20970
uniprot id: A0A806LX17
names: Similarity
messages: Belongs to the peptidase C40 family.

1145276:T479 RS21975
gene id: 1145276:T479_RS21975
uniprot id: A0A806LUV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1145276:T479 RS03960
gene id: 1145276:T479_RS03960
uniprot id: A0A806LKT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1145276:T479 RS20345
gene id: 1145276:T479_RS20345
uniprot id: A0A806LQ31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1145276:T479 RS21260
gene id: 1145276:T479_RS21260
uniprot id: A0A806LUI1
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS20365
gene id: 1145276:T479_RS20365
uniprot id: A0A806LU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1145276:T479 RS21755
gene id: 1145276:T479_RS21755
uniprot id: A0A806LUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1145276:T479 RS01970
gene id: 1145276:T479_RS01970
uniprot id: A0A806LP33
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1145276:T479 RS18340
gene id: 1145276:T479_RS18340
uniprot id: A0A806LTG8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1145276:T479 RS01860
gene id: 1145276:T479_RS01860
uniprot id: A0A806LEW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1145276:T479 RS22055
gene id: 1145276:T479_RS22055
uniprot id: A0A806LQW8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1145276:T479 RS09990
gene id: 1145276:T479_RS09990
uniprot id: A0A806LVY0
names: Subcellular Location Annotation
messages: Cell membrane

1145276:T479 RS02230
gene id: 1145276:T479_RS02230
uniprot id: A0A806LMR1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS08155
gene id: 1145276:T479_RS08155
uniprot id: A0A806LN14
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS15920
gene id: 1145276:T479_RS15920
uniprot id: A0A806LSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS06400
gene id: 1145276:T479_RS06400
uniprot id: A0A806LPW9
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS01100
gene id: 1145276:T479_RS01100
uniprot id: A0A806LM56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS13770
gene id: 1145276:T479_RS13770
uniprot id: A0A806LKZ7
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS04445
gene id: 1145276:T479_RS04445
uniprot id: A0A806LQD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1145276:T479 RS08615
gene id: 1145276:T479_RS08615
uniprot id: A0A806LN88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS11280
gene id: 1145276:T479_RS11280
uniprot id: A0A806LPH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1145276:T479 RS22585
gene id: 1145276:T479_RS22585
uniprot id: A0A806LV51
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1145276:T479 RS11005
gene id: 1145276:T479_RS11005
uniprot id: A0A806LI92
names: Similarity
messages: Belongs to the carbamate kinase family.

1145276:T479 RS21835
gene id: 1145276:T479_RS21835
uniprot id: A0A806LXH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1145276:T479 RS19705
gene id: 1145276:T479_RS19705
uniprot id: A0A806LMG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1145276:T479 RS04525
gene id: 1145276:T479_RS04525
uniprot id: A0A806LMR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS04225
gene id: 1145276:T479_RS04225
uniprot id: A0A806LG69
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1145276:T479 RS07515
gene id: 1145276:T479_RS07515
uniprot id: A0A806LP83
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1145276:T479 RS01805
gene id: 1145276:T479_RS01805
uniprot id: A0A806LJL6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1145276:T479 RS07195
gene id: 1145276:T479_RS07195
uniprot id: A0A806LP19
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

1145276:T479 RS14615
gene id: 1145276:T479_RS14615
uniprot id: A0A806LK14
names: Similarity
messages: Belongs to the manganese catalase family.

1145276:T479 RS10245
gene id: 1145276:T479_RS10245
uniprot id: A0A806LPL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1145276:T479 RS06380
gene id: 1145276:T479_RS06380
uniprot id: A0A806LM16
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1145276:T479 RS17140
gene id: 1145276:T479_RS17140
uniprot id: A0A806LLE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS09025
gene id: 1145276:T479_RS09025
uniprot id: A0A806LHF5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1145276:T479 RS07320
gene id: 1145276:T479_RS07320
uniprot id: A0A806LRW0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS18550
gene id: 1145276:T479_RS18550
uniprot id: A0A806LVV3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1145276:T479 RS14410
gene id: 1145276:T479_RS14410
uniprot id: A0A806LSM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1145276:T479 RS04640
gene id: 1145276:T479_RS04640
uniprot id: A0A806LGK0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1145276:T479 RS06870
gene id: 1145276:T479_RS06870
uniprot id: A0A806LMC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1145276:T479 RS07075
gene id: 1145276:T479_RS07075
uniprot id: A0A806LN39
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS20465
gene id: 1145276:T479_RS20465
uniprot id: A0A806LU25
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1145276:T479 RS21775
gene id: 1145276:T479_RS21775
uniprot id: A0A806LZB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1145276:T479 RS01140
gene id: 1145276:T479_RS01140
uniprot id: A0A806LDB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS00365
gene id: 1145276:T479_RS00365
uniprot id: A0A806LLU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1145276:T479 RS07560
gene id: 1145276:T479_RS07560
uniprot id: A0A806LJ47
names: Similarity
messages: Belongs to the peptidase A31 family.

1145276:T479 RS17525
gene id: 1145276:T479_RS17525
uniprot id: A0A806LVD5
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS09230
gene id: 1145276:T479_RS09230
uniprot id: A0A806LQ46
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS14835
gene id: 1145276:T479_RS14835
uniprot id: A0A806LKA1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1145276:T479 RS03655
gene id: 1145276:T479_RS03655
uniprot id: A0A806LKM0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1145276:T479 RS04480
gene id: 1145276:T479_RS04480
uniprot id: A0A806LL40
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS20325
gene id: 1145276:T479_RS20325
uniprot id: A0A806LYI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1145276:T479 RS13045
gene id: 1145276:T479_RS13045
uniprot id: A0A806LLL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1145276:T479 RS03255
gene id: 1145276:T479_RS03255
uniprot id: A0A806LFM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1145276:T479 RS21465
gene id: 1145276:T479_RS21465
uniprot id: A0A806LX04
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS00890
gene id: 1145276:T479_RS00890
uniprot id: A0A806LKY2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS08880
gene id: 1145276:T479_RS08880
uniprot id: A0A806LP06
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1145276:T479 RS11075
gene id: 1145276:T479_RS11075
uniprot id: A0A806LSB5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1145276:T479 RS07860
gene id: 1145276:T479_RS07860
uniprot id: A0A806LQN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1145276:T479 RS16635
gene id: 1145276:T479_RS16635
uniprot id: A0A806LV11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1145276:T479 RS15395
gene id: 1145276:T479_RS15395
uniprot id: A0A806LLV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1145276:T479 RS01130
gene id: 1145276:T479_RS01130
uniprot id: A0A806LJC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1145276:T479 RS21935
gene id: 1145276:T479_RS21935
uniprot id: A0A806LZE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1145276:T479 RS01865
gene id: 1145276:T479_RS01865
uniprot id: A0A806LJP3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1145276:T479 RS01935
gene id: 1145276:T479_RS01935
uniprot id: A0A806LDM4
names: Similarity
messages: Belongs to the peptidase M24B family.

1145276:T479 RS10665
gene id: 1145276:T479_RS10665
uniprot id: A0A806LKL8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS21410
gene id: 1145276:T479_RS21410
uniprot id: A0A806LPR9
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1145276:T479 RS03915
gene id: 1145276:T479_RS03915
uniprot id: A0A806LEV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1145276:T479 RS22580
gene id: 1145276:T479_RS22580
uniprot id: A0A806LWP6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1145276:T479 RS05060
gene id: 1145276:T479_RS05060
uniprot id: A0A806LFJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1145276:T479 RS01425
gene id: 1145276:T479_RS01425
uniprot id: A0A806LNT5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1145276:T479 RS07600
gene id: 1145276:T479_RS07600
uniprot id: A0A806LQH4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1145276:T479 RS17925
gene id: 1145276:T479_RS17925
uniprot id: A0A806LSV1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS13495
gene id: 1145276:T479_RS13495
uniprot id: A0A806LQF7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1145276:T479 RS04780
gene id: 1145276:T479_RS04780
uniprot id: A0A806LF91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1145276:T479 RS21705
gene id: 1145276:T479_RS21705
uniprot id: A0A806LNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS18505
gene id: 1145276:T479_RS18505
uniprot id: A0A806LLV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1145276:T479 RS08230
gene id: 1145276:T479_RS08230
uniprot id: A0A806LSC9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1145276:T479 RS05950
gene id: 1145276:T479_RS05950
uniprot id: A0A806LR57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1145276:T479 RS19910
gene id: 1145276:T479_RS19910
uniprot id: A0A806LPU8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1145276:T479 RS01065
gene id: 1145276:T479_RS01065
uniprot id: A0A806LJ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1145276:T479 RS08595
gene id: 1145276:T479_RS08595
uniprot id: A0A806LR13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1145276:T479 RS13580
gene id: 1145276:T479_RS13580
uniprot id: A0A806LJG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1145276:T479 RS17065
gene id: 1145276:T479_RS17065
uniprot id: A0A806LSE0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1145276:T479 RS14030
gene id: 1145276:T479_RS14030
uniprot id: A0A806LRF0
names: Similarity
messages: Belongs to the GSP E family.

1145276:T479 RS13230
gene id: 1145276:T479_RS13230
uniprot id: A0A806LT99
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1145276:T479 RS02830
gene id: 1145276:T479_RS02830
uniprot id: A0A806LGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1145276:T479 RS08625
gene id: 1145276:T479_RS08625
uniprot id: A0A806LN64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1145276:T479 RS00020
gene id: 1145276:T479_RS00020
uniprot id: A0A806LFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1145276:T479 RS21830
gene id: 1145276:T479_RS21830
uniprot id: A0A806LV39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1145276:T479 RS06185
gene id: 1145276:T479_RS06185
uniprot id: A0A806LNK5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1145276:T479 RS04175
gene id: 1145276:T479_RS04175
uniprot id: A0A806LF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

1145276:T479 RS05835
gene id: 1145276:T479_RS05835
uniprot id: A0A806LFX0
names: Similarity
messages: Belongs to the PspA/IM30 family.

1145276:T479 RS21380
gene id: 1145276:T479_RS21380
uniprot id: A0A806LND0
names: Similarity
messages: Belongs to the IucA/IucC family.

1145276:T479 RS08110
gene id: 1145276:T479_RS08110
uniprot id: A0A806LMX4
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS03860
gene id: 1145276:T479_RS03860
uniprot id: A0A806LKR3
names: Subcellular Location Annotation
messages: Membrane

1145276:T479 RS09430
gene id: 1145276:T479_RS09430
uniprot id: A0A806LJ00
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS18520
gene id: 1145276:T479_RS18520
uniprot id: A0A806LT07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1145276:T479 RS05965
gene id: 1145276:T479_RS05965
uniprot id: A0A806LFX1
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

1145276:T479 RS06720
gene id: 1145276:T479_RS06720
uniprot id: A0A806LM79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1145276:T479 RS22380
gene id: 1145276:T479_RS22380
uniprot id: A0A806LV17
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1145276:T479 RS13390
gene id: 1145276:T479_RS13390
uniprot id: A0A806LS35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1145276:T479 RS06760
gene id: 1145276:T479_RS06760
uniprot id: A0A806LMA5
names: Similarity
messages: Belongs to the MoaD family.

1145276:T479 RS02600
gene id: 1145276:T479_RS02600
uniprot id: A0A806LPF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1145276:T479 RS16670
gene id: 1145276:T479_RS16670
uniprot id: A0A806LS30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1145276:T479 RS07345
gene id: 1145276:T479_RS07345
uniprot id: A0A806LP53
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1145276:T479 RS19970
gene id: 1145276:T479_RS19970
uniprot id: A0A806LTS9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1145276:T479 RS10410
gene id: 1145276:T479_RS10410
uniprot id: A0A806LTI6
names: Similarity
messages: Belongs to the DinB family.

1145276:T479 RS18390
gene id: 1145276:T479_RS18390
uniprot id: A0A806LXC5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1145276:T479 RS06210
gene id: 1145276:T479_RS06210
uniprot id: A0A806LR99
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1145276:T479 RS02610
gene id: 1145276:T479_RS02610
uniprot id: A0A806LMY2
names: Similarity
messages: Belongs to the FBPase class 2 family.

1145276:T479 RS02200
gene id: 1145276:T479_RS02200
uniprot id: A0A806LLI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS14210
gene id: 1145276:T479_RS14210
uniprot id: A0A806LQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1145276:T479 RS02325
gene id: 1145276:T479_RS02325
uniprot id: A0A806LPA5
names: Similarity
messages: Belongs to the ThiD family.

1145276:T479 RS14495
gene id: 1145276:T479_RS14495
uniprot id: A0A806LK38
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1145276:T479 RS03045
gene id: 1145276:T479_RS03045
uniprot id: A0A806LKA2
names: Similarity
messages: Belongs to the peptidase C40 family.

1145276:T479 RS00760
gene id: 1145276:T479_RS00760
uniprot id: A0A806LM15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1145276:T479 RS20310
gene id: 1145276:T479_RS20310
uniprot id: A0A806LP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS13610
gene id: 1145276:T479_RS13610
uniprot id: A0A806LJM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1145276:T479 RS07750
gene id: 1145276:T479_RS07750
uniprot id: A0A806LNG6
names: Similarity
messages: Belongs to the MQO family.

1145276:T479 RS04025
gene id: 1145276:T479_RS04025
uniprot id: A0A806LEX6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1145276:T479 RS08920
gene id: 1145276:T479_RS08920
uniprot id: A0A806LNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1145276:T479 RS15040
gene id: 1145276:T479_RS15040
uniprot id: A0A806LKE4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1145276:T479 RS22795
gene id: 1145276:T479_RS22795
uniprot id: A0A806LK76
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1145276:T479 RS10395
gene id: 1145276:T479_RS10395
uniprot id: A0A806LJD8
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

1145276:T479 RS01080
gene id: 1145276:T479_RS01080
uniprot id: A0A806LDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1145276:T479 RS12220
gene id: 1145276:T479_RS12220
uniprot id: A0A806LPT4
names: Similarity
messages: Belongs to the peptidase S58 family.