1138822:PL11 RS07900
gene id: 1138822:PL11_RS07900
uniprot id: A0A1S6QJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1138822:PL11 RS06685
gene id: 1138822:PL11_RS06685
uniprot id: A0A1S6QJ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS02645
gene id: 1138822:PL11_RS02645
uniprot id: A0A1S6QH01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1138822:PL11 RS02260
gene id: 1138822:PL11_RS02260
uniprot id: A0A1S6QGS0
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS02915
gene id: 1138822:PL11_RS02915
uniprot id: A0A1S6QH38
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1138822:PL11 RS08255
gene id: 1138822:PL11_RS08255
uniprot id: A0A1S6QJV8
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1138822:PL11 RS03215
gene id: 1138822:PL11_RS03215
uniprot id: A0A1S6QHA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1138822:PL11 RS01165
gene id: 1138822:PL11_RS01165
uniprot id: A0A1S6QG77
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

1138822:PL11 RS04205
gene id: 1138822:PL11_RS04205
uniprot id: A0A1S6QHT2
names: Similarity
messages: Belongs to the peptidase C40 family.

1138822:PL11 RS08595
gene id: 1138822:PL11_RS08595
uniprot id: A0A1S6QK52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1138822:PL11 RS03610
gene id: 1138822:PL11_RS03610
uniprot id: A0A1S6QHI3
names: Similarity
messages: Belongs to the ArsC family.

1138822:PL11 RS02320
gene id: 1138822:PL11_RS02320
uniprot id: A0A1S6QGT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS05315
gene id: 1138822:PL11_RS05315
uniprot id: A0A1S6QIF6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS04575
gene id: 1138822:PL11_RS04575
uniprot id: A0A1S6QI12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06630
gene id: 1138822:PL11_RS06630
uniprot id: A0A1S6QJ56
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1138822:PL11 RS09430
gene id: 1138822:PL11_RS09430
uniprot id: A0A1S6QKG9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1138822:PL11 RS10160
gene id: 1138822:PL11_RS10160
uniprot id: A0A1S6QKV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1138822:PL11 RS08775
gene id: 1138822:PL11_RS08775
uniprot id: A0A1S6QK84
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS07700
gene id: 1138822:PL11_RS07700
uniprot id: A0A1S6QJP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1138822:PL11 RS08345
gene id: 1138822:PL11_RS08345
uniprot id: A0A1S6QJW9
names: Similarity
messages: Belongs to the universal stress protein A family.

1138822:PL11 RS09735
gene id: 1138822:PL11_RS09735
uniprot id: A0A1S6QKN1
names: Function
messages: Required for transformation and DNA binding.

1138822:PL11 RS02145
gene id: 1138822:PL11_RS02145
uniprot id: A0A1S6QGR0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1138822:PL11 RS08640
gene id: 1138822:PL11_RS08640
uniprot id: A0A1S6QK41
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1138822:PL11 RS02795
gene id: 1138822:PL11_RS02795
uniprot id: A0A1S6QH31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08575
gene id: 1138822:PL11_RS08575
uniprot id: A0A1S6QK17
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1138822:PL11 RS00605
gene id: 1138822:PL11_RS00605
uniprot id: A0A1S6QG06
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1138822:PL11 RS01380
gene id: 1138822:PL11_RS01380
uniprot id: A0A1S6QGB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1138822:PL11 RS08765
gene id: 1138822:PL11_RS08765
uniprot id: A0A1S6QK37
names: Similarity
messages: Belongs to the asp23 family.

1138822:PL11 RS01510
gene id: 1138822:PL11_RS01510
uniprot id: A0A1S6QGE6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1138822:PL11 RS06145
gene id: 1138822:PL11_RS06145
uniprot id: A0A1S6QIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1138822:PL11 RS00635
gene id: 1138822:PL11_RS00635
uniprot id: A0A1S6QG07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1138822:PL11 RS03340
gene id: 1138822:PL11_RS03340
uniprot id: A0A1S6QHD6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS06625
gene id: 1138822:PL11_RS06625
uniprot id: A0A1S6QJ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1138822:PL11 RS06545
gene id: 1138822:PL11_RS06545
uniprot id: A0A1S6QJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1138822:PL11 RS08100
gene id: 1138822:PL11_RS08100
uniprot id: A0A1S6QJR2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1138822:PL11 RS05440
gene id: 1138822:PL11_RS05440
uniprot id: A0A1S6QIH2
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS00430
gene id: 1138822:PL11_RS00430
uniprot id: A0A1S6QFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS07270
gene id: 1138822:PL11_RS07270
uniprot id: A0A1S6QJF1
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1138822:PL11 RS05925
gene id: 1138822:PL11_RS05925
uniprot id: A0A1S6QIS1
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS04010
gene id: 1138822:PL11_RS04010
uniprot id: A0A1S6QKZ9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1138822:PL11 RS00285
gene id: 1138822:PL11_RS00285
uniprot id: A0A1S6QFV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04810
gene id: 1138822:PL11_RS04810
uniprot id: A0A1S6QI71
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1138822:PL11 RS00640
gene id: 1138822:PL11_RS00640
uniprot id: A0A1S6QG08
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1138822:PL11 RS02375
gene id: 1138822:PL11_RS02375
uniprot id: A0A1S6QGV1
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS05910
gene id: 1138822:PL11_RS05910
uniprot id: A0A1S6QIQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1138822:PL11 RS09195
gene id: 1138822:PL11_RS09195
uniprot id: A0A1S6QKC1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1138822:PL11 RS07585
gene id: 1138822:PL11_RS07585
uniprot id: A0A1S6QJJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02785
gene id: 1138822:PL11_RS02785
uniprot id: A0A1S6QH32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1138822:PL11 RS03395
gene id: 1138822:PL11_RS03395
uniprot id: A0A1S6QHD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1138822:PL11 RS06520
gene id: 1138822:PL11_RS06520
uniprot id: A0A1S6QJ18
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1138822:PL11 RS09980
gene id: 1138822:PL11_RS09980
uniprot id: A0A1S6QKV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1138822:PL11 RS03355
gene id: 1138822:PL11_RS03355
uniprot id: A0A1S6QHD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS07660
gene id: 1138822:PL11_RS07660
uniprot id: A0A1S6QJL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1138822:PL11 RS05355
gene id: 1138822:PL11_RS05355
uniprot id: A0A1S6QIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09995
gene id: 1138822:PL11_RS09995
uniprot id: A0A1S6QKU1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1138822:PL11 RS04790
gene id: 1138822:PL11_RS04790
uniprot id: A0A1S6QI43
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1138822:PL11 RS08170
gene id: 1138822:PL11_RS08170
uniprot id: A0A1S6QJW5
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS07930
gene id: 1138822:PL11_RS07930
uniprot id: A0A1S6QJS4
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS08545
gene id: 1138822:PL11_RS08545
uniprot id: A0A1S6QK35
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1138822:PL11 RS05880
gene id: 1138822:PL11_RS05880
uniprot id: A0A1S6QIQ7
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS07085
gene id: 1138822:PL11_RS07085
uniprot id: A0A1S6QJB5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1138822:PL11 RS02965
gene id: 1138822:PL11_RS02965
uniprot id: A0A1S6QH52
names: Similarity
messages: Belongs to the agmatine deiminase family.

1138822:PL11 RS01825
gene id: 1138822:PL11_RS01825
uniprot id: A0A1S6QGL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06640
gene id: 1138822:PL11_RS06640
uniprot id: A0A1S6QJ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08935
gene id: 1138822:PL11_RS08935
uniprot id: A0A1S6QK96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1138822:PL11 RS05120
gene id: 1138822:PL11_RS05120
uniprot id: A0A1S6QIC6
names: Similarity
messages: Belongs to the fructosamine kinase family.

1138822:PL11 RS04540
gene id: 1138822:PL11_RS04540
uniprot id: A0A1S6QI09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS07580
gene id: 1138822:PL11_RS07580
uniprot id: A0A1S6QJL2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1138822:PL11 RS06295
gene id: 1138822:PL11_RS06295
uniprot id: A0A1S6QIX7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1138822:PL11 RS01370
gene id: 1138822:PL11_RS01370
uniprot id: A0A1S6QGC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1138822:PL11 RS02920
gene id: 1138822:PL11_RS02920
uniprot id: A0A1S6QH51
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

1138822:PL11 RS06405
gene id: 1138822:PL11_RS06405
uniprot id: A0A1S6QIZ8
names: Similarity
messages: Belongs to the DCK/DGK family.

1138822:PL11 RS08335
gene id: 1138822:PL11_RS08335
uniprot id: A0A1S6QK00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1138822:PL11 RS01655
gene id: 1138822:PL11_RS01655
uniprot id: A0A1S6QGI6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1138822:PL11 RS03420
gene id: 1138822:PL11_RS03420
uniprot id: A0A1S6QHF0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1138822:PL11 RS09340
gene id: 1138822:PL11_RS09340
uniprot id: A0A1S6QKJ2
names: Similarity
messages: Belongs to the CvfB family.

1138822:PL11 RS09855
gene id: 1138822:PL11_RS09855
uniprot id: A0A1S6QKS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1138822:PL11 RS07220
gene id: 1138822:PL11_RS07220
uniprot id: A0A1S6QJE2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1138822:PL11 RS06600
gene id: 1138822:PL11_RS06600
uniprot id: A0A1S6QJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1138822:PL11 RS08465
gene id: 1138822:PL11_RS08465
uniprot id: A0A1S6QK18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1138822:PL11 RS06515
gene id: 1138822:PL11_RS06515
uniprot id: A0A1S6QJ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1138822:PL11 RS09465
gene id: 1138822:PL11_RS09465
uniprot id: A0A1S6QKK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS06305
gene id: 1138822:PL11_RS06305
uniprot id: A0A1S6QIY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1138822:PL11 RS06680
gene id: 1138822:PL11_RS06680
uniprot id: A0A1S6QL44
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1138822:PL11 RS02525
gene id: 1138822:PL11_RS02525
uniprot id: A0A1S6QGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1138822:PL11 RS06480
gene id: 1138822:PL11_RS06480
uniprot id: A0A1S6QJ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1138822:PL11 RS08700
gene id: 1138822:PL11_RS08700
uniprot id: A0A1S6QK70
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1138822:PL11 RS07910
gene id: 1138822:PL11_RS07910
uniprot id: A0A1S6QJQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08020
gene id: 1138822:PL11_RS08020
uniprot id: A0A1S6QJV0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1138822:PL11 RS06050
gene id: 1138822:PL11_RS06050
uniprot id: A0A1S6QIU2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1138822:PL11 RS05970
gene id: 1138822:PL11_RS05970
uniprot id: A0A1S6QIR6
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS01385
gene id: 1138822:PL11_RS01385
uniprot id: A0A1S6QGC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1138822:PL11 RS04860
gene id: 1138822:PL11_RS04860
uniprot id: A0A1S6QI66
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1138822:PL11 RS03500
gene id: 1138822:PL11_RS03500
uniprot id: A0A1S6QHF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1138822:PL11 RS05505
gene id: 1138822:PL11_RS05505
uniprot id: A0A1S6QII5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS06460
gene id: 1138822:PL11_RS06460
uniprot id: A0A1S6QJ15
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1138822:PL11 RS02945
gene id: 1138822:PL11_RS02945
uniprot id: A0A1S6QH65
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1138822:PL11 RS05870
gene id: 1138822:PL11_RS05870
uniprot id: A0A1S6QIQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1138822:PL11 RS04400
gene id: 1138822:PL11_RS04400
uniprot id: A0A1S6QHX9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1138822:PL11 RS09315
gene id: 1138822:PL11_RS09315
uniprot id: A0A1S6QKH0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1138822:PL11 RS06355
gene id: 1138822:PL11_RS06355
uniprot id: A0A1S6QIY7
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS01525
gene id: 1138822:PL11_RS01525
uniprot id: A0A1S6QGE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS05620
gene id: 1138822:PL11_RS05620
uniprot id: A0A1S6QIK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02985
gene id: 1138822:PL11_RS02985
uniprot id: A0A1S6QH77
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS04295
gene id: 1138822:PL11_RS04295
uniprot id: A0A1S6QHV7
names: Similarity
messages: Belongs to the threonine synthase family.

1138822:PL11 RS08795
gene id: 1138822:PL11_RS08795
uniprot id: A0A1S6QK78
names: Similarity
messages: Belongs to the TlyA family.

1138822:PL11 RS09815
gene id: 1138822:PL11_RS09815
uniprot id: A0A1S6QKQ0
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS08130
gene id: 1138822:PL11_RS08130
uniprot id: A0A1S6QJU7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1138822:PL11 RS01590
gene id: 1138822:PL11_RS01590
uniprot id: A0A1S6QGH3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1138822:PL11 RS08645
gene id: 1138822:PL11_RS08645
uniprot id: A0A1S6QK63
names: Similarity
messages: Belongs to the HesB/IscA family.

1138822:PL11 RS00820
gene id: 1138822:PL11_RS00820
uniprot id: A0A1S6QG47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1138822:PL11 RS04185
gene id: 1138822:PL11_RS04185
uniprot id: A0A1S6QHT9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS07215
gene id: 1138822:PL11_RS07215
uniprot id: A0A1S6QJF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS08385
gene id: 1138822:PL11_RS08385
uniprot id: A0A1S6QJZ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1138822:PL11 RS09180
gene id: 1138822:PL11_RS09180
uniprot id: A0A1S6QKD5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS06585
gene id: 1138822:PL11_RS06585
uniprot id: A0A1S6QJ32
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1138822:PL11 RS09000
gene id: 1138822:PL11_RS09000
uniprot id: A0A1S6QKE2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1138822:PL11 RS04715
gene id: 1138822:PL11_RS04715
uniprot id: A0A1S6QI39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1138822:PL11 RS09140
gene id: 1138822:PL11_RS09140
uniprot id: A0A1S6QKA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS07845
gene id: 1138822:PL11_RS07845
uniprot id: A0A1S6QJP9
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS09955
gene id: 1138822:PL11_RS09955
uniprot id: A0A1S6QKU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1138822:PL11 RS07615
gene id: 1138822:PL11_RS07615
uniprot id: A0A1S6QJL0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1138822:PL11 RS06500
gene id: 1138822:PL11_RS06500
uniprot id: A0A1S6QJ04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1138822:PL11 RS10140
gene id: 1138822:PL11_RS10140
uniprot id: A0A1S6QL08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1138822:PL11 RS06720
gene id: 1138822:PL11_RS06720
uniprot id: A0A1S6QJ57
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1138822:PL11 RS05290
gene id: 1138822:PL11_RS05290
uniprot id: A0A1S6QIE3
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1138822:PL11 RS04145
gene id: 1138822:PL11_RS04145
uniprot id: A0A1S6QHS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1138822:PL11 RS08890
gene id: 1138822:PL11_RS08890
uniprot id: A0A1S6QKC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1138822:PL11 RS00805
gene id: 1138822:PL11_RS00805
uniprot id: A0A1S6QG37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1138822:PL11 RS08495
gene id: 1138822:PL11_RS08495
uniprot id: A0A1S6QK27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1138822:PL11 RS06820
gene id: 1138822:PL11_RS06820
uniprot id: A0A1S6QJ67
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1138822:PL11 RS07205
gene id: 1138822:PL11_RS07205
uniprot id: A0A1S6QJA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1138822:PL11 RS07030
gene id: 1138822:PL11_RS07030
uniprot id: A0A1S6QJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS01790
gene id: 1138822:PL11_RS01790
uniprot id: A0A1S6QGI8
names: Similarity
messages: Belongs to the UPF0751 family.

1138822:PL11 RS10150
gene id: 1138822:PL11_RS10150
uniprot id: A0A1S6QKY5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1138822:PL11 RS05515
gene id: 1138822:PL11_RS05515
uniprot id: A0A1S6QII6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1138822:PL11 RS07235
gene id: 1138822:PL11_RS07235
uniprot id: A0A1S6QJF9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1138822:PL11 RS01295
gene id: 1138822:PL11_RS01295
uniprot id: A0A1S6QGB3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1138822:PL11 RS04120
gene id: 1138822:PL11_RS04120
uniprot id: A0A1S6QHU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1138822:PL11 RS03410
gene id: 1138822:PL11_RS03410
uniprot id: A0A1S6QHF9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1138822:PL11 RS08065
gene id: 1138822:PL11_RS08065
uniprot id: A0A1S6QJU0
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1138822:PL11 RS03380
gene id: 1138822:PL11_RS03380
uniprot id: A0A1S6QHE5
names: Similarity
messages: Belongs to the GARS family.

1138822:PL11 RS02030
gene id: 1138822:PL11_RS02030
uniprot id: A0A1S6QGN4
names: Similarity
messages: Belongs to the TPP enzyme family.

1138822:PL11 RS04995
gene id: 1138822:PL11_RS04995
uniprot id: A0A1S6QI80
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04060
gene id: 1138822:PL11_RS04060
uniprot id: A0A1S6QHT1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1138822:PL11 RS08555
gene id: 1138822:PL11_RS08555
uniprot id: A0A1S6QK02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1138822:PL11 RS04235
gene id: 1138822:PL11_RS04235
uniprot id: A0A1S6QHU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1138822:PL11 RS08915
gene id: 1138822:PL11_RS08915
uniprot id: A0A1S6QK61
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1138822:PL11 RS06360
gene id: 1138822:PL11_RS06360
uniprot id: A0A1S6QIY4
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1138822:PL11 RS05475
gene id: 1138822:PL11_RS05475
uniprot id: A0A1S6QII4
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS05635
gene id: 1138822:PL11_RS05635
uniprot id: A0A1S6QL32
names: Subcellular Location Annotation
messages: Cell membrane

1138822:PL11 RS07690
gene id: 1138822:PL11_RS07690
uniprot id: A0A1S6QJL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1138822:PL11 RS09360
gene id: 1138822:PL11_RS09360
uniprot id: A0A1S6QL79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1138822:PL11 RS06615
gene id: 1138822:PL11_RS06615
uniprot id: A0A1S6QJ40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1138822:PL11 RS10055
gene id: 1138822:PL11_RS10055
uniprot id: A0A1S6QKW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1138822:PL11 RS09715
gene id: 1138822:PL11_RS09715
uniprot id: A0A1S6QKL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1138822:PL11 RS03575
gene id: 1138822:PL11_RS03575
uniprot id: A0A1S6QHI0
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS06695
gene id: 1138822:PL11_RS06695
uniprot id: A0A1S6QL48
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1138822:PL11 RS00695
gene id: 1138822:PL11_RS00695
uniprot id: A0A1S6QG18
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1138822:PL11 RS09265
gene id: 1138822:PL11_RS09265
uniprot id: A0A1S6QKG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06590
gene id: 1138822:PL11_RS06590
uniprot id: A0A1S6QJ33
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1138822:PL11 RS08470
gene id: 1138822:PL11_RS08470
uniprot id: A0A1S6QK04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1138822:PL11 RS09785
gene id: 1138822:PL11_RS09785
uniprot id: A0A1S6QKN7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1138822:PL11 RS09620
gene id: 1138822:PL11_RS09620
uniprot id: A0A1S6QKM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1138822:PL11 RS00775
gene id: 1138822:PL11_RS00775
uniprot id: A0A1S6QG45
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1138822:PL11 RS06875
gene id: 1138822:PL11_RS06875
uniprot id: A0A1S6QJ83
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1138822:PL11 RS07430
gene id: 1138822:PL11_RS07430
uniprot id: A0A1S6QL63
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1138822:PL11 RS09790
gene id: 1138822:PL11_RS09790
uniprot id: A0A1S6QKU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1138822:PL11 RS03920
gene id: 1138822:PL11_RS03920
uniprot id: A0A1S6QHN1
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

1138822:PL11 RS08905
gene id: 1138822:PL11_RS08905
uniprot id: A0A1S6QKA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1138822:PL11 RS06805
gene id: 1138822:PL11_RS06805
uniprot id: A0A1S6QJ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1138822:PL11 RS04135
gene id: 1138822:PL11_RS04135
uniprot id: A0A1S6QHS9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS07125
gene id: 1138822:PL11_RS07125
uniprot id: A0A1S6QJB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS07635
gene id: 1138822:PL11_RS07635
uniprot id: A0A1S6QJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1138822:PL11 RS07340
gene id: 1138822:PL11_RS07340
uniprot id: A0A1S6QJI0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS03985
gene id: 1138822:PL11_RS03985
uniprot id: A0A1S6QHP4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1138822:PL11 RS03065
gene id: 1138822:PL11_RS03065
uniprot id: A0A1S6QH79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1138822:PL11 RS06535
gene id: 1138822:PL11_RS06535
uniprot id: A0A1S6QJ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1138822:PL11 RS01360
gene id: 1138822:PL11_RS01360
uniprot id: A0A1S6QGB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1138822:PL11 RS06490
gene id: 1138822:PL11_RS06490
uniprot id: A0A1S6QJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1138822:PL11 RS06125
gene id: 1138822:PL11_RS06125
uniprot id: A0A1S6QIV2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1138822:PL11 RS06525
gene id: 1138822:PL11_RS06525
uniprot id: A0A1S6QJ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1138822:PL11 RS00500
gene id: 1138822:PL11_RS00500
uniprot id: A0A1S6QFY6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1138822:PL11 RS04410
gene id: 1138822:PL11_RS04410
uniprot id: A0A1S6QHY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04125
gene id: 1138822:PL11_RS04125
uniprot id: A0A1S6QHT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1138822:PL11 RS08735
gene id: 1138822:PL11_RS08735
uniprot id: A0A1S6QK89
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1138822:PL11 RS06735
gene id: 1138822:PL11_RS06735
uniprot id: A0A1S6QJ75
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1138822:PL11 RS05110
gene id: 1138822:PL11_RS05110
uniprot id: A0A1S6QIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06700
gene id: 1138822:PL11_RS06700
uniprot id: A0A1S6QJ74
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1138822:PL11 RS04210
gene id: 1138822:PL11_RS04210
uniprot id: A0A1S6QHT5
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

1138822:PL11 RS03935
gene id: 1138822:PL11_RS03935
uniprot id: A0A1S6QHR1
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the N-terminal section; belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1138822:PL11 RS02280
gene id: 1138822:PL11_RS02280
uniprot id: A0A1S6QGU0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1138822:PL11 RS09535
gene id: 1138822:PL11_RS09535
uniprot id: A0A1S6QKP3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1138822:PL11 RS08630
gene id: 1138822:PL11_RS08630
uniprot id: A0A1S6QK65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1138822:PL11 RS03715
gene id: 1138822:PL11_RS03715
uniprot id: A0A1S6QHK1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1138822:PL11 RS06225
gene id: 1138822:PL11_RS06225
uniprot id: A0A1S6QIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1138822:PL11 RS09830
gene id: 1138822:PL11_RS09830
uniprot id: A0A1S6QKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1138822:PL11 RS04055
gene id: 1138822:PL11_RS04055
uniprot id: A0A1S6QHQ6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1138822:PL11 RS01425
gene id: 1138822:PL11_RS01425
uniprot id: A0A1S6QGC0
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

1138822:PL11 RS06315
gene id: 1138822:PL11_RS06315
uniprot id: A0A1S6QIX6
names: Similarity
messages: Belongs to the UPF0145 family.

1138822:PL11 RS04390
gene id: 1138822:PL11_RS04390
uniprot id: A0A1S6QHX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02330
gene id: 1138822:PL11_RS02330
uniprot id: A0A1S6QGV3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1138822:PL11 RS01460
gene id: 1138822:PL11_RS01460
uniprot id: A0A1S6QGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1138822:PL11 RS03205
gene id: 1138822:PL11_RS03205
uniprot id: A0A1S6QHA7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1138822:PL11 RS04000
gene id: 1138822:PL11_RS04000
uniprot id: A0A1S6QHR3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09335
gene id: 1138822:PL11_RS09335
uniprot id: A0A1S6QKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1138822:PL11 RS05525
gene id: 1138822:PL11_RS05525
uniprot id: A0A1S6QIJ0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1138822:PL11 RS03490
gene id: 1138822:PL11_RS03490
uniprot id: A0A1S6QHG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS10000
gene id: 1138822:PL11_RS10000
uniprot id: A0A1S6QKU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1138822:PL11 RS08800
gene id: 1138822:PL11_RS08800
uniprot id: A0A1S6QK67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1138822:PL11 RS01960
gene id: 1138822:PL11_RS01960
uniprot id: A0A1S6QGM4
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1138822:PL11 RS00415
gene id: 1138822:PL11_RS00415
uniprot id: A0A1S6QFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06830
gene id: 1138822:PL11_RS06830
uniprot id: A0A1S6QJ81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS09975
gene id: 1138822:PL11_RS09975
uniprot id: A0A1S6QKW9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1138822:PL11 RS09945
gene id: 1138822:PL11_RS09945
uniprot id: A0A1S6QKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS00515
gene id: 1138822:PL11_RS00515
uniprot id: A0A1S6QFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1138822:PL11 RS09640
gene id: 1138822:PL11_RS09640
uniprot id: A0A1S6QKR5
names: Similarity
messages: Belongs to the UPF0213 family.

1138822:PL11 RS07785
gene id: 1138822:PL11_RS07785
uniprot id: A0A1S6QJL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1138822:PL11 RS07460
gene id: 1138822:PL11_RS07460
uniprot id: A0A1S6QJF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS02665
gene id: 1138822:PL11_RS02665
uniprot id: A0A1S6QH09
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS07075
gene id: 1138822:PL11_RS07075
uniprot id: A0A1S6QL58
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS05160
gene id: 1138822:PL11_RS05160
uniprot id: A0A1S6QID1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1138822:PL11 RS00220
gene id: 1138822:PL11_RS00220
uniprot id: A0A1S6QFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02540
gene id: 1138822:PL11_RS02540
uniprot id: A0A1S6QGY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1138822:PL11 RS00735
gene id: 1138822:PL11_RS00735
uniprot id: A0A1S6QG26
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1138822:PL11 RS08110
gene id: 1138822:PL11_RS08110
uniprot id: A0A1S6QJW4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1138822:PL11 RS03745
gene id: 1138822:PL11_RS03745
uniprot id: A0A1S6QHK6
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS06645
gene id: 1138822:PL11_RS06645
uniprot id: A0A1S6QJ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1138822:PL11 RS09990
gene id: 1138822:PL11_RS09990
uniprot id: A0A1S6QKY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1138822:PL11 RS09435
gene id: 1138822:PL11_RS09435
uniprot id: A0A1S6QKM7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1138822:PL11 RS08060
gene id: 1138822:PL11_RS08060
uniprot id: A0A1S6QJV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1138822:PL11 RS02195
gene id: 1138822:PL11_RS02195
uniprot id: A0A1S6QGR7
names: Similarity
messages: Belongs to the SfsA family.

1138822:PL11 RS08670
gene id: 1138822:PL11_RS08670
uniprot id: A0A1S6QK50
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS06025
gene id: 1138822:PL11_RS06025
uniprot id: A0A1S6QIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

1138822:PL11 RS09865
gene id: 1138822:PL11_RS09865
uniprot id: A0A1S6QKR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1138822:PL11 RS09805
gene id: 1138822:PL11_RS09805
uniprot id: A0A1S6QKR3
names: Similarity
messages: Belongs to the thioredoxin family.

1138822:PL11 RS00715
gene id: 1138822:PL11_RS00715
uniprot id: A0A1S6QG30
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1138822:PL11 RS03835
gene id: 1138822:PL11_RS03835
uniprot id: A0A1S6QHN0
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS07140
gene id: 1138822:PL11_RS07140
uniprot id: A0A1S6QJC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1138822:PL11 RS08970
gene id: 1138822:PL11_RS08970
uniprot id: A0A1S6QK72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1138822:PL11 RS05095
gene id: 1138822:PL11_RS05095
uniprot id: A0A1S6QL33
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS09670
gene id: 1138822:PL11_RS09670
uniprot id: A0A1S6QKL2
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1138822:PL11 RS03385
gene id: 1138822:PL11_RS03385
uniprot id: A0A1S6QHD8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1138822:PL11 RS10090
gene id: 1138822:PL11_RS10090
uniprot id: A0A1S6QKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1138822:PL11 RS04980
gene id: 1138822:PL11_RS04980
uniprot id: A0A1S6QI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1138822:PL11 RS07210
gene id: 1138822:PL11_RS07210
uniprot id: A0A1S6QJB0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS03260
gene id: 1138822:PL11_RS03260
uniprot id: A0A1S6QHB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS00915
gene id: 1138822:PL11_RS00915
uniprot id: A0A1S6QG64
names: Similarity
messages: Belongs to the ArsC family.

1138822:PL11 RS01235
gene id: 1138822:PL11_RS01235
uniprot id: A0A1S6QGA3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1138822:PL11 RS09290
gene id: 1138822:PL11_RS09290
uniprot id: A0A1S6QKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1138822:PL11 RS01305
gene id: 1138822:PL11_RS01305
uniprot id: A0A1S6QGA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1138822:PL11 RS05045
gene id: 1138822:PL11_RS05045
uniprot id: A0A1S6QI90
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1138822:PL11 RS01210
gene id: 1138822:PL11_RS01210
uniprot id: A0A1S6QG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS03350
gene id: 1138822:PL11_RS03350
uniprot id: A0A1S6QHC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1138822:PL11 RS00550
gene id: 1138822:PL11_RS00550
uniprot id: A0A1S6QG01
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1138822:PL11 RS09545
gene id: 1138822:PL11_RS09545
uniprot id: A0A1S6QKL1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1138822:PL11 RS02445
gene id: 1138822:PL11_RS02445
uniprot id: A0A1S6QGX5
names: Similarity
messages: Belongs to the ArsC family.

1138822:PL11 RS06610
gene id: 1138822:PL11_RS06610
uniprot id: A0A1S6QJ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1138822:PL11 RS07285
gene id: 1138822:PL11_RS07285
uniprot id: A0A1S6QJH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1138822:PL11 RS03550
gene id: 1138822:PL11_RS03550
uniprot id: A0A1S6QHG2
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS07985
gene id: 1138822:PL11_RS07985
uniprot id: A0A1S6QJP0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1138822:PL11 RS03895
gene id: 1138822:PL11_RS03895
uniprot id: A0A1S6QHP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1138822:PL11 RS09025
gene id: 1138822:PL11_RS09025
uniprot id: A0A1S6QK87
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1138822:PL11 RS09065
gene id: 1138822:PL11_RS09065
uniprot id: A0A1S6QKC0
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS04265
gene id: 1138822:PL11_RS04265
uniprot id: A0A1S6QHU7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1138822:PL11 RS07325
gene id: 1138822:PL11_RS07325
uniprot id: A0A1S6QJF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1138822:PL11 RS03945
gene id: 1138822:PL11_RS03945
uniprot id: A0A1S6QHQ0
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS03255
gene id: 1138822:PL11_RS03255
uniprot id: A0A1S6QHC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS05680
gene id: 1138822:PL11_RS05680
uniprot id: A0A1S6QIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

1138822:PL11 RS02360
gene id: 1138822:PL11_RS02360
uniprot id: A0A1S6QGV4
names: Similarity
messages: Belongs to the thioredoxin family.

1138822:PL11 RS03365
gene id: 1138822:PL11_RS03365
uniprot id: A0A1S6QHD7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1138822:PL11 RS04870
gene id: 1138822:PL11_RS04870
uniprot id: A0A1S6QI68
names: Similarity
messages: Belongs to the peptidase C40 family.

1138822:PL11 RS07435
gene id: 1138822:PL11_RS07435
uniprot id: A0A1S6QJG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1138822:PL11 RS02380
gene id: 1138822:PL11_RS02380
uniprot id: A0A1S6QGW6
names: Similarity
messages: Belongs to the peptidase C40 family.

1138822:PL11 RS07955
gene id: 1138822:PL11_RS07955
uniprot id: A0A1S6QJR4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1138822:PL11 RS09210
gene id: 1138822:PL11_RS09210
uniprot id: A0A1S6QKF1
names: Similarity
messages: Belongs to the DprA/Smf family.

1138822:PL11 RS04230
gene id: 1138822:PL11_RS04230
uniprot id: A0A1S6QHV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1138822:PL11 RS07675
gene id: 1138822:PL11_RS07675
uniprot id: A0A1S6QJJ4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1138822:PL11 RS00830
gene id: 1138822:PL11_RS00830
uniprot id: A0A1S6QG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS05375
gene id: 1138822:PL11_RS05375
uniprot id: A0A1S6QIG7
names: Similarity
messages: Belongs to the asparaginase 1 family.

1138822:PL11 RS06510
gene id: 1138822:PL11_RS06510
uniprot id: A0A1S6QJ23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1138822:PL11 RS05250
gene id: 1138822:PL11_RS05250
uniprot id: A0A1S6QIE1
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1138822:PL11 RS06780
gene id: 1138822:PL11_RS06780
uniprot id: A0A1S6QJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1138822:PL11 RS00535
gene id: 1138822:PL11_RS00535
uniprot id: A0A1S6QFZ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1138822:PL11 RS08815
gene id: 1138822:PL11_RS08815
uniprot id: A0A1S6QK47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1138822:PL11 RS05540
gene id: 1138822:PL11_RS05540
uniprot id: A0A1S6QIK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

1138822:PL11 RS00815
gene id: 1138822:PL11_RS00815
uniprot id: A0A1S6QG40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS04700
gene id: 1138822:PL11_RS04700
uniprot id: A0A1S6QI34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09590
gene id: 1138822:PL11_RS09590
uniprot id: A0A1S6QKQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1138822:PL11 RS02720
gene id: 1138822:PL11_RS02720
uniprot id: A0A1S6QH27
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1138822:PL11 RS09750
gene id: 1138822:PL11_RS09750
uniprot id: A0A1S6QKP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1138822:PL11 RS07810
gene id: 1138822:PL11_RS07810
uniprot id: A0A1S6QJR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1138822:PL11 RS08730
gene id: 1138822:PL11_RS08730
uniprot id: A0A1S6QK43
names: Similarity
messages: Belongs to the UPF0237 family.

1138822:PL11 RS09840
gene id: 1138822:PL11_RS09840
uniprot id: A0A1S6QKV3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1138822:PL11 RS04830
gene id: 1138822:PL11_RS04830
uniprot id: A0A1S6QI51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1138822:PL11 RS06760
gene id: 1138822:PL11_RS06760
uniprot id: A0A1S6QJ84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1138822:PL11 RS04090
gene id: 1138822:PL11_RS04090
uniprot id: A0A1S6QHR5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1138822:PL11 RS09845
gene id: 1138822:PL11_RS09845
uniprot id: A0A1S6QKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1138822:PL11 RS04950
gene id: 1138822:PL11_RS04950
uniprot id: A0A1S6QI82
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1138822:PL11 RS07825
gene id: 1138822:PL11_RS07825
uniprot id: A0A1S6QJQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1138822:PL11 RS01395
gene id: 1138822:PL11_RS01395
uniprot id: A0A1S6QGD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS01275
gene id: 1138822:PL11_RS01275
uniprot id: A0A1S6QG98
names: Subcellular Location Annotation
messages: cell wall

1138822:PL11 RS08940
gene id: 1138822:PL11_RS08940
uniprot id: A0A1S6QK81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1138822:PL11 RS10075
gene id: 1138822:PL11_RS10075
uniprot id: A0A1S6QKZ2
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS03425
gene id: 1138822:PL11_RS03425
uniprot id: A0A1S6QHF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1138822:PL11 RS07960
gene id: 1138822:PL11_RS07960
uniprot id: A0A1S6QJQ9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1138822:PL11 RS02220
gene id: 1138822:PL11_RS02220
uniprot id: A0A1S6QGS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS03960
gene id: 1138822:PL11_RS03960
uniprot id: A0A1S6QHP6
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS05535
gene id: 1138822:PL11_RS05535
uniprot id: A0A1S6QIJ5
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the N-terminal section; belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1138822:PL11 RS05575
gene id: 1138822:PL11_RS05575
uniprot id: A0A1S6QIK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1138822:PL11 RS08870
gene id: 1138822:PL11_RS08870
uniprot id: A0A1S6QKA0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1138822:PL11 RS06920
gene id: 1138822:PL11_RS06920
uniprot id: A0A1S6QL76
names: Similarity
messages: Belongs to the peptidase M29 family.

1138822:PL11 RS05305
gene id: 1138822:PL11_RS05305
uniprot id: A0A1S6QID8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1138822:PL11 RS03590
gene id: 1138822:PL11_RS03590
uniprot id: A0A1S6QHH6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS02875
gene id: 1138822:PL11_RS02875
uniprot id: A0A1S6QH56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1138822:PL11 RS02690
gene id: 1138822:PL11_RS02690
uniprot id: A0A1S6QH15
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1138822:PL11 RS02700
gene id: 1138822:PL11_RS02700
uniprot id: A0A1S6QH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS07950
gene id: 1138822:PL11_RS07950
uniprot id: A0A1S6QJS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1138822:PL11 RS09060
gene id: 1138822:PL11_RS09060
uniprot id: A0A1S6QKD1
names: Similarity
messages: Belongs to the CarB family.

1138822:PL11 RS08240
gene id: 1138822:PL11_RS08240
uniprot id: A0A1S6QJY1
names: Similarity
messages: Belongs to the universal stress protein A family.

1138822:PL11 RS07335
gene id: 1138822:PL11_RS07335
uniprot id: A0A1S6QJF7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1138822:PL11 RS09365
gene id: 1138822:PL11_RS09365
uniprot id: A0A1S6QKJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1138822:PL11 RS09490
gene id: 1138822:PL11_RS09490
uniprot id: A0A1S6QKK8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1138822:PL11 RS09900
gene id: 1138822:PL11_RS09900
uniprot id: A0A1S6QKS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1138822:PL11 RS03270
gene id: 1138822:PL11_RS03270
uniprot id: A0A1S6QHC2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1138822:PL11 RS04105
gene id: 1138822:PL11_RS04105
uniprot id: A0A1S6QHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1138822:PL11 RS09870
gene id: 1138822:PL11_RS09870
uniprot id: A0A1S6QKT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1138822:PL11 RS06505
gene id: 1138822:PL11_RS06505
uniprot id: A0A1S6QJ05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1138822:PL11 RS04475
gene id: 1138822:PL11_RS04475
uniprot id: A0A1S6QHZ3
names: Similarity
messages: Belongs to the peptidase C1 family.

1138822:PL11 RS08015
gene id: 1138822:PL11_RS08015
uniprot id: A0A1S6QJR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1138822:PL11 RS04690
gene id: 1138822:PL11_RS04690
uniprot id: A0A1S6QI35
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS05360
gene id: 1138822:PL11_RS05360
uniprot id: A0A1S6QIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04500
gene id: 1138822:PL11_RS04500
uniprot id: A0A1S6QHZ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1138822:PL11 RS00835
gene id: 1138822:PL11_RS00835
uniprot id: A0A1S6QG53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1138822:PL11 RS07655
gene id: 1138822:PL11_RS07655
uniprot id: A0A1S6QJL4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1138822:PL11 RS08490
gene id: 1138822:PL11_RS08490
uniprot id: A0A1S6QK13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1138822:PL11 RS01270
gene id: 1138822:PL11_RS01270
uniprot id: A0A1S6QG97
names: Subcellular Location Annotation
messages: cell wall

1138822:PL11 RS06300
gene id: 1138822:PL11_RS06300
uniprot id: A0A1S6QIY3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1138822:PL11 RS05310
gene id: 1138822:PL11_RS05310
uniprot id: A0A1S6QIE5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1138822:PL11 RS00525
gene id: 1138822:PL11_RS00525
uniprot id: A0A1S6QFY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS01615
gene id: 1138822:PL11_RS01615
uniprot id: A0A1S6QL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1138822:PL11 RS04855
gene id: 1138822:PL11_RS04855
uniprot id: A0A1S6QI64
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS03415
gene id: 1138822:PL11_RS03415
uniprot id: A0A1S6QHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1138822:PL11 RS10010
gene id: 1138822:PL11_RS10010
uniprot id: A0A1S6QKS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1138822:PL11 RS03345
gene id: 1138822:PL11_RS03345
uniprot id: A0A1S6QHC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS04560
gene id: 1138822:PL11_RS04560
uniprot id: A0A1S6QI07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02630
gene id: 1138822:PL11_RS02630
uniprot id: A0A1S6QH05
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1138822:PL11 RS09380
gene id: 1138822:PL11_RS09380
uniprot id: A0A1S6QKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1138822:PL11 RS03245
gene id: 1138822:PL11_RS03245
uniprot id: A0A1S6QHA1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09810
gene id: 1138822:PL11_RS09810
uniprot id: A0A1S6QKN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1138822:PL11 RS07575
gene id: 1138822:PL11_RS07575
uniprot id: A0A1S6QJH3
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS02615
gene id: 1138822:PL11_RS02615
uniprot id: A0A1S6QH00
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1138822:PL11 RS00875
gene id: 1138822:PL11_RS00875
uniprot id: A0A1S6QG57
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1138822:PL11 RS00725
gene id: 1138822:PL11_RS00725
uniprot id: A0A1S6QG31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1138822:PL11 RS06095
gene id: 1138822:PL11_RS06095
uniprot id: A0A1S6QIU9
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS02455
gene id: 1138822:PL11_RS02455
uniprot id: A0A1S6QGX3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1138822:PL11 RS06730
gene id: 1138822:PL11_RS06730
uniprot id: A0A1S6QJ37
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1138822:PL11 RS04800
gene id: 1138822:PL11_RS04800
uniprot id: A0A1S6QI52
names: Similarity
messages: Belongs to the XFP family.

1138822:PL11 RS00510
gene id: 1138822:PL11_RS00510
uniprot id: A0A1S6QFZ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1138822:PL11 RS07160
gene id: 1138822:PL11_RS07160
uniprot id: A0A1S6QJA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09885
gene id: 1138822:PL11_RS09885
uniprot id: A0A1S6QKQ9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1138822:PL11 RS01365
gene id: 1138822:PL11_RS01365
uniprot id: A0A1S6QGB0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS00910
gene id: 1138822:PL11_RS00910
uniprot id: A0A1S6QG52
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1138822:PL11 RS06485
gene id: 1138822:PL11_RS06485
uniprot id: A0A1S6QJ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1138822:PL11 RS03615
gene id: 1138822:PL11_RS03615
uniprot id: A0A1S6QHJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1138822:PL11 RS09635
gene id: 1138822:PL11_RS09635
uniprot id: A0A1S6QKK4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1138822:PL11 RS07715
gene id: 1138822:PL11_RS07715
uniprot id: A0A1S6QJN1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1138822:PL11 RS03730
gene id: 1138822:PL11_RS03730
uniprot id: A0A1S6QHL1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1138822:PL11 RS04195
gene id: 1138822:PL11_RS04195
uniprot id: A0A1S6QHT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1138822:PL11 RS06100
gene id: 1138822:PL11_RS06100
uniprot id: A0A1S6QIV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1138822:PL11 RS09245
gene id: 1138822:PL11_RS09245
uniprot id: A0A1S6QKC3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1138822:PL11 RS06635
gene id: 1138822:PL11_RS06635
uniprot id: A0A1S6QJ39
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1138822:PL11 RS03005
gene id: 1138822:PL11_RS03005
uniprot id: A0A1S6QH76
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1138822:PL11 RS01135
gene id: 1138822:PL11_RS01135
uniprot id: A0A1S6QG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1138822:PL11 RS01635
gene id: 1138822:PL11_RS01635
uniprot id: A0A1S6QGG8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1138822:PL11 RS09960
gene id: 1138822:PL11_RS09960
uniprot id: A0A1S6QKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1138822:PL11 RS09835
gene id: 1138822:PL11_RS09835
uniprot id: A0A1S6QKP9
names: Similarity
messages: Belongs to the UPF0297 family.

1138822:PL11 RS03405
gene id: 1138822:PL11_RS03405
uniprot id: A0A1S6QHE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1138822:PL11 RS06400
gene id: 1138822:PL11_RS06400
uniprot id: A0A1S6QJ03
names: Similarity
messages: Belongs to the aldolase LacD family.

1138822:PL11 RS02750
gene id: 1138822:PL11_RS02750
uniprot id: A0A1S6QH14
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1138822:PL11 RS01900
gene id: 1138822:PL11_RS01900
uniprot id: A0A1S6QGL6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09145
gene id: 1138822:PL11_RS09145
uniprot id: A0A1S6QKA6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1138822:PL11 RS05000
gene id: 1138822:PL11_RS05000
uniprot id: A0A1S6QI92
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1138822:PL11 RS00905
gene id: 1138822:PL11_RS00905
uniprot id: A0A1S6QG56
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family.

1138822:PL11 RS05890
gene id: 1138822:PL11_RS05890
uniprot id: A0A1S6QIQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1138822:PL11 RS06310
gene id: 1138822:PL11_RS06310
uniprot id: A0A1S6QIX3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1138822:PL11 RS08780
gene id: 1138822:PL11_RS08780
uniprot id: A0A1S6QK71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1138822:PL11 RS02130
gene id: 1138822:PL11_RS02130
uniprot id: A0A1S6QGR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1138822:PL11 RS05560
gene id: 1138822:PL11_RS05560
uniprot id: A0A1S6QIK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS05545
gene id: 1138822:PL11_RS05545
uniprot id: A0A1S6QIJ3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1138822:PL11 RS06910
gene id: 1138822:PL11_RS06910
uniprot id: A0A1S6QJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1138822:PL11 RS09030
gene id: 1138822:PL11_RS09030
uniprot id: A0A1S6QKD0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1138822:PL11 RS09460
gene id: 1138822:PL11_RS09460
uniprot id: A0A1S6QKG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS03310
gene id: 1138822:PL11_RS03310
uniprot id: A0A1S6QHC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.

1138822:PL11 RS08805
gene id: 1138822:PL11_RS08805
uniprot id: A0A1S6QK93
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1138822:PL11 RS07695
gene id: 1138822:PL11_RS07695
uniprot id: A0A1S6QJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09520
gene id: 1138822:PL11_RS09520
uniprot id: A0A1S6QKN9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1138822:PL11 RS03690
gene id: 1138822:PL11_RS03690
uniprot id: A0A1S6QHJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1138822:PL11 RS06740
gene id: 1138822:PL11_RS06740
uniprot id: A0A1S6QJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09625
gene id: 1138822:PL11_RS09625
uniprot id: A0A1S6QKQ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1138822:PL11 RS05275
gene id: 1138822:PL11_RS05275
uniprot id: A0A1S6QIG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS08930
gene id: 1138822:PL11_RS08930
uniprot id: A0A1S6QKB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1138822:PL11 RS06620
gene id: 1138822:PL11_RS06620
uniprot id: A0A1S6QJ41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1138822:PL11 RS04115
gene id: 1138822:PL11_RS04115
uniprot id: A0A1S6QHR7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1138822:PL11 RS00880
gene id: 1138822:PL11_RS00880
uniprot id: A0A1S6QG61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS04020
gene id: 1138822:PL11_RS04020
uniprot id: A0A1S6QHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS07015
gene id: 1138822:PL11_RS07015
uniprot id: A0A1S6QJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1138822:PL11 RS00620
gene id: 1138822:PL11_RS00620
uniprot id: A0A1S6QG12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1138822:PL11 RS07945
gene id: 1138822:PL11_RS07945
uniprot id: A0A1S6QJT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1138822:PL11 RS03115
gene id: 1138822:PL11_RS03115
uniprot id: A0A1S6QH93
names: Subcellular Location Annotation
messages: Cell membrane

1138822:PL11 RS04075
gene id: 1138822:PL11_RS04075
uniprot id: A0A1S6QHS8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1138822:PL11 RS10110
gene id: 1138822:PL11_RS10110
uniprot id: A0A1S6QKU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1138822:PL11 RS09500
gene id: 1138822:PL11_RS09500
uniprot id: A0A1S6QKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1138822:PL11 RS08745
gene id: 1138822:PL11_RS08745
uniprot id: A0A1S6QK68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1138822:PL11 RS03400
gene id: 1138822:PL11_RS03400
uniprot id: A0A1S6QHD0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS01345
gene id: 1138822:PL11_RS01345
uniprot id: A0A1S6QGC9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1138822:PL11 RS06655
gene id: 1138822:PL11_RS06655
uniprot id: A0A1S6QL67
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS06470
gene id: 1138822:PL11_RS06470
uniprot id: A0A1S6QJ11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1138822:PL11 RS01280
gene id: 1138822:PL11_RS01280
uniprot id: A0A1S6QGA9
names: Subcellular Location Annotation
messages: cell wall

1138822:PL11 RS01950
gene id: 1138822:PL11_RS01950
uniprot id: A0A1S6QGN2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1138822:PL11 RS08825
gene id: 1138822:PL11_RS08825
uniprot id: A0A1S6QK94
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS10105
gene id: 1138822:PL11_RS10105
uniprot id: A0A1S6QKX6
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS07380
gene id: 1138822:PL11_RS07380
uniprot id: A0A1S6QJG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS00655
gene id: 1138822:PL11_RS00655
uniprot id: A0A1S6QG21
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1138822:PL11 RS03555
gene id: 1138822:PL11_RS03555
uniprot id: A0A1S6QHG5
names: Similarity
messages: Belongs to the UPF0177 family.

1138822:PL11 RS03130
gene id: 1138822:PL11_RS03130
uniprot id: A0A1S6QH81
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1138822:PL11 RS06665
gene id: 1138822:PL11_RS06665
uniprot id: A0A1S6QJ64
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1138822:PL11 RS07600
gene id: 1138822:PL11_RS07600
uniprot id: A0A1S6QJM2
names: Similarity
messages: Belongs to the peptidase C1 family.

1138822:PL11 RS09035
gene id: 1138822:PL11_RS09035
uniprot id: A0A1S6QKE1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1138822:PL11 RS04215
gene id: 1138822:PL11_RS04215
uniprot id: A0A1S6QHT7
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1138822:PL11 RS01320
gene id: 1138822:PL11_RS01320
uniprot id: A0A1S6QKZ5
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS06800
gene id: 1138822:PL11_RS06800
uniprot id: A0A1S6QJ66
names: Similarity
messages: Belongs to the fabD family.

1138822:PL11 RS06555
gene id: 1138822:PL11_RS06555
uniprot id: A0A1S6QJ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1138822:PL11 RS04490
gene id: 1138822:PL11_RS04490
uniprot id: A0A1S6QI00
names: Subcellular Location Annotation
messages: Cell membrane

1138822:PL11 RS07710
gene id: 1138822:PL11_RS07710
uniprot id: A0A1S6QJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1138822:PL11 RS00800
gene id: 1138822:PL11_RS00800
uniprot id: A0A1S6QG32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1138822:PL11 RS04015
gene id: 1138822:PL11_RS04015
uniprot id: A0A1S6QHR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1138822:PL11 RS07820
gene id: 1138822:PL11_RS07820
uniprot id: A0A1S6QJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1138822:PL11 RS02500
gene id: 1138822:PL11_RS02500
uniprot id: A0A1S6QGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1138822:PL11 RS03890
gene id: 1138822:PL11_RS03890
uniprot id: A0A1S6QHP0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04290
gene id: 1138822:PL11_RS04290
uniprot id: A0A1S6QHW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS08245
gene id: 1138822:PL11_RS08245
uniprot id: A0A1S6QJX4
names: Similarity
messages: Belongs to the DCK/DGK family.

1138822:PL11 RS01310
gene id: 1138822:PL11_RS01310
uniprot id: A0A1S6QGB7
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

1138822:PL11 RS07725
gene id: 1138822:PL11_RS07725
uniprot id: A0A1S6QJK5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1138822:PL11 RS06725
gene id: 1138822:PL11_RS06725
uniprot id: A0A1S6QJ36
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1138822:PL11 RS06365
gene id: 1138822:PL11_RS06365
uniprot id: A0A1S6QIY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1138822:PL11 RS01935
gene id: 1138822:PL11_RS01935
uniprot id: A0A1S6QGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1138822:PL11 RS00135
gene id: 1138822:PL11_RS00135
uniprot id: A0A1S6QFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1138822:PL11 RS04685
gene id: 1138822:PL11_RS04685
uniprot id: A0A1S6QI22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1138822:PL11 RS04495
gene id: 1138822:PL11_RS04495
uniprot id: A0A1S6QHZ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1138822:PL11 RS00300
gene id: 1138822:PL11_RS00300
uniprot id: A0A1S6QFX3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1138822:PL11 RS09415
gene id: 1138822:PL11_RS09415
uniprot id: A0A1S6QKK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1138822:PL11 RS02425
gene id: 1138822:PL11_RS02425
uniprot id: A0A1S6QGV2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS10175
gene id: 1138822:PL11_RS10175
uniprot id: A0A1S6QL14
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1138822:PL11 RS03825
gene id: 1138822:PL11_RS03825
uniprot id: A0A1S6QHL7
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1138822:PL11 RS06715
gene id: 1138822:PL11_RS06715
uniprot id: A0A1S6QJ55
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1138822:PL11 RS09660
gene id: 1138822:PL11_RS09660
uniprot id: A0A1S6QL64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1138822:PL11 RS07680
gene id: 1138822:PL11_RS07680
uniprot id: A0A1S6QJN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1138822:PL11 RS00630
gene id: 1138822:PL11_RS00630
uniprot id: A0A1S6QG04
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1138822:PL11 RS02860
gene id: 1138822:PL11_RS02860
uniprot id: A0A1S6QH28
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1138822:PL11 RS04930
gene id: 1138822:PL11_RS04930
uniprot id: A0A1S6QI78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1138822:PL11 RS04825
gene id: 1138822:PL11_RS04825
uniprot id: A0A1S6QI60
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1138822:PL11 RS00445
gene id: 1138822:PL11_RS00445
uniprot id: A0A1S6QFY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1138822:PL11 RS09115
gene id: 1138822:PL11_RS09115
uniprot id: A0A1S6QKD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1138822:PL11 RS04875
gene id: 1138822:PL11_RS04875
uniprot id: A0A1S6QI72
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1138822:PL11 RS09175
gene id: 1138822:PL11_RS09175
uniprot id: A0A1S6QKE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS07260
gene id: 1138822:PL11_RS07260
uniprot id: A0A1S6QJC0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1138822:PL11 RS07605
gene id: 1138822:PL11_RS07605
uniprot id: A0A1S6QJK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1138822:PL11 RS06815
gene id: 1138822:PL11_RS06815
uniprot id: A0A1S6QL35
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1138822:PL11 RS08195
gene id: 1138822:PL11_RS08195
uniprot id: A0A1S6QJV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02680
gene id: 1138822:PL11_RS02680
uniprot id: A0A1S6QH17
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1138822:PL11 RS10165
gene id: 1138822:PL11_RS10165
uniprot id: A0A1S6QKX0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1138822:PL11 RS08445
gene id: 1138822:PL11_RS08445
uniprot id: A0A1S6QK15
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS02955
gene id: 1138822:PL11_RS02955
uniprot id: A0A1S6QH63
names: Caution
names: Similarity
messages: Belongs to the agmatine deiminase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS08565
gene id: 1138822:PL11_RS08565
uniprot id: A0A1S6QK44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS01575
gene id: 1138822:PL11_RS01575
uniprot id: A0A1S6QGF0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1138822:PL11 RS03900
gene id: 1138822:PL11_RS03900
uniprot id: A0A1S6QHN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS07425
gene id: 1138822:PL11_RS07425
uniprot id: A0A1S6QJG6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1138822:PL11 RS07965
gene id: 1138822:PL11_RS07965
uniprot id: A0A1S6QJU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1138822:PL11 RS03655
gene id: 1138822:PL11_RS03655
uniprot id: A0A1S6QHI8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

1138822:PL11 RS07720
gene id: 1138822:PL11_RS07720
uniprot id: A0A1S6QJJ9
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

1138822:PL11 RS09600
gene id: 1138822:PL11_RS09600
uniprot id: A0A1S6QKL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1138822:PL11 RS09205
gene id: 1138822:PL11_RS09205
uniprot id: A0A1S6QKG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1138822:PL11 RS07245
gene id: 1138822:PL11_RS07245
uniprot id: A0A1S6QJE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1138822:PL11 RS03675
gene id: 1138822:PL11_RS03675
uniprot id: A0A1S6QHK2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09555
gene id: 1138822:PL11_RS09555
uniprot id: A0A1S6QKI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1138822:PL11 RS01260
gene id: 1138822:PL11_RS01260
uniprot id: A0A1S6QG95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1138822:PL11 RS03850
gene id: 1138822:PL11_RS03850
uniprot id: A0A1S6QHN3
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS07905
gene id: 1138822:PL11_RS07905
uniprot id: A0A1S6QJQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1138822:PL11 RS03815
gene id: 1138822:PL11_RS03815
uniprot id: A0A1S6QHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS03375
gene id: 1138822:PL11_RS03375
uniprot id: A0A1S6QHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS07080
gene id: 1138822:PL11_RS07080
uniprot id: A0A1S6QJB2
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS09200
gene id: 1138822:PL11_RS09200
uniprot id: A0A1S6QKF7
names: Similarity
messages: Belongs to the peptidase C69 family.

1138822:PL11 RS03685
gene id: 1138822:PL11_RS03685
uniprot id: A0A1S6QHK4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1138822:PL11 RS07290
gene id: 1138822:PL11_RS07290
uniprot id: A0A1S6QJE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1138822:PL11 RS03485
gene id: 1138822:PL11_RS03485
uniprot id: A0A1S6QHF7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1138822:PL11 RS10095
gene id: 1138822:PL11_RS10095
uniprot id: A0A1S6QKW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS00490
gene id: 1138822:PL11_RS00490
uniprot id: A0A1S6QFX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS08925
gene id: 1138822:PL11_RS08925
uniprot id: A0A1S6QKB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1138822:PL11 RS04530
gene id: 1138822:PL11_RS04530
uniprot id: A0A1S6QI04
names: Similarity
messages: Belongs to the TrpF family.

1138822:PL11 RS05860
gene id: 1138822:PL11_RS05860
uniprot id: A0A1S6QIQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1138822:PL11 RS07835
gene id: 1138822:PL11_RS07835
uniprot id: A0A1S6QJM8
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS09070
gene id: 1138822:PL11_RS09070
uniprot id: A0A1S6QKD8
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1138822:PL11 RS01400
gene id: 1138822:PL11_RS01400
uniprot id: A0A1S6QGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06710
gene id: 1138822:PL11_RS06710
uniprot id: A0A1S6QJ50
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1138822:PL11 RS05225
gene id: 1138822:PL11_RS05225
uniprot id: A0A1S6QIE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1138822:PL11 RS05460
gene id: 1138822:PL11_RS05460
uniprot id: A0A1S6QIH8
names: Similarity
messages: Belongs to the peptidase C59 family.

1138822:PL11 RS00740
gene id: 1138822:PL11_RS00740
uniprot id: A0A1S6QG24
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1138822:PL11 RS09055
gene id: 1138822:PL11_RS09055
uniprot id: A0A1S6QKE8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1138822:PL11 RS04150
gene id: 1138822:PL11_RS04150
uniprot id: A0A1S6QHT0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1138822:PL11 RS08225
gene id: 1138822:PL11_RS08225
uniprot id: A0A1S6QJX3
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS08600
gene id: 1138822:PL11_RS08600
uniprot id: A0A1S6QJZ8
names: Similarity
messages: Belongs to the acylphosphatase family.

1138822:PL11 RS07035
gene id: 1138822:PL11_RS07035
uniprot id: A0A1S6QJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09370
gene id: 1138822:PL11_RS09370
uniprot id: A0A1S6QKI2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

1138822:PL11 RS03720
gene id: 1138822:PL11_RS03720
uniprot id: A0A1S6QHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

1138822:PL11 RS09220
gene id: 1138822:PL11_RS09220
uniprot id: A0A1S6QKH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1138822:PL11 RS03585
gene id: 1138822:PL11_RS03585
uniprot id: A0A1S6QHI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1138822:PL11 RS08395
gene id: 1138822:PL11_RS08395
uniprot id: A0A1S6QK07
names: Similarity
messages: Belongs to the UPF0342 family.

1138822:PL11 RS05405
gene id: 1138822:PL11_RS05405
uniprot id: A0A1S6QIH9
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS06925
gene id: 1138822:PL11_RS06925
uniprot id: A0A1S6QJ87
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1138822:PL11 RS06075
gene id: 1138822:PL11_RS06075
uniprot id: A0A1S6QIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS00895
gene id: 1138822:PL11_RS00895
uniprot id: A0A1S6QG59
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1138822:PL11 RS02510
gene id: 1138822:PL11_RS02510
uniprot id: A0A1S6QGY3
names: Similarity
messages: Belongs to the carbamate kinase family.

1138822:PL11 RS08830
gene id: 1138822:PL11_RS08830
uniprot id: A0A1S6QK80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1138822:PL11 RS05555
gene id: 1138822:PL11_RS05555
uniprot id: A0A1S6QIJ8
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1138822:PL11 RS00240
gene id: 1138822:PL11_RS00240
uniprot id: A0A1S6QFV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS00720
gene id: 1138822:PL11_RS00720
uniprot id: A0A1S6QG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1138822:PL11 RS10070
gene id: 1138822:PL11_RS10070
uniprot id: A0A1S6QKX2
names: Similarity
messages: Belongs to the GcvH family.

1138822:PL11 RS09405
gene id: 1138822:PL11_RS09405
uniprot id: A0A1S6QKF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1138822:PL11 RS08840
gene id: 1138822:PL11_RS08840
uniprot id: A0A1S6QKB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1138822:PL11 RS03160
gene id: 1138822:PL11_RS03160
uniprot id: A0A1S6QHA0
names: Caution
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS09280
gene id: 1138822:PL11_RS09280
uniprot id: A0A1S6QKG5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1138822:PL11 RS03845
gene id: 1138822:PL11_RS03845
uniprot id: A0A1S6QHM9
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS02515
gene id: 1138822:PL11_RS02515
uniprot id: A0A1S6QGX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1138822:PL11 RS03295
gene id: 1138822:PL11_RS03295
uniprot id: A0A1S6QHB2
names: Similarity
messages: Belongs to the EamA transporter family.

1138822:PL11 RS00245
gene id: 1138822:PL11_RS00245
uniprot id: A0A1S6QFV4
names: Similarity
messages: Belongs to the LOG family.

1138822:PL11 RS05280
gene id: 1138822:PL11_RS05280
uniprot id: A0A1S6QIF0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1138822:PL11 RS01080
gene id: 1138822:PL11_RS01080
uniprot id: A0A1S6QKX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS03525
gene id: 1138822:PL11_RS03525
uniprot id: A0A1S6QHH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1138822:PL11 RS08770
gene id: 1138822:PL11_RS08770
uniprot id: A0A1S6QK76
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1138822:PL11 RS09310
gene id: 1138822:PL11_RS09310
uniprot id: A0A1S6QKI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1138822:PL11 RS08190
gene id: 1138822:PL11_RS08190
uniprot id: A0A1S6QJW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1138822:PL11 RS09680
gene id: 1138822:PL11_RS09680
uniprot id: A0A1S6QKR2
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS07970
gene id: 1138822:PL11_RS07970
uniprot id: A0A1S6QJS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1138822:PL11 RS08295
gene id: 1138822:PL11_RS08295
uniprot id: A0A1S6QJY7
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1138822:PL11 RS05760
gene id: 1138822:PL11_RS05760
uniprot id: A0A1S6QIP4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1138822:PL11 RS08355
gene id: 1138822:PL11_RS08355
uniprot id: A0A1S6QJZ4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1138822:PL11 RS00580
gene id: 1138822:PL11_RS00580
uniprot id: A0A1S6QFZ4
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS02285
gene id: 1138822:PL11_RS02285
uniprot id: A0A1S6QGU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1138822:PL11 RS06560
gene id: 1138822:PL11_RS06560
uniprot id: A0A1S6QJ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1138822:PL11 RS00585
gene id: 1138822:PL11_RS00585
uniprot id: A0A1S6QFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1138822:PL11 RS09915
gene id: 1138822:PL11_RS09915
uniprot id: A0A1S6QKS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1138822:PL11 RS04820
gene id: 1138822:PL11_RS04820
uniprot id: A0A1S6QI65
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS00115
gene id: 1138822:PL11_RS00115
uniprot id: A0A1S6QFS9
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS02940
gene id: 1138822:PL11_RS02940
uniprot id: A0A1S6QH59
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1138822:PL11 RS09610
gene id: 1138822:PL11_RS09610
uniprot id: A0A1S6QKJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1138822:PL11 RS04240
gene id: 1138822:PL11_RS04240
uniprot id: A0A1S6QHV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1138822:PL11 RS03980
gene id: 1138822:PL11_RS03980
uniprot id: A0A1S6QHP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1138822:PL11 RS01600
gene id: 1138822:PL11_RS01600
uniprot id: A0A1S6QGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS03740
gene id: 1138822:PL11_RS03740
uniprot id: A0A1S6QHL4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1138822:PL11 RS04775
gene id: 1138822:PL11_RS04775
uniprot id: A0A1S6QI48
names: Similarity
messages: Belongs to the polypeptide deformylase family.

1138822:PL11 RS08290
gene id: 1138822:PL11_RS08290
uniprot id: A0A1S6QJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08420
gene id: 1138822:PL11_RS08420
uniprot id: A0A1S6QJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1138822:PL11 RS08785
gene id: 1138822:PL11_RS08785
uniprot id: A0A1S6QK53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1138822:PL11 RS08045
gene id: 1138822:PL11_RS08045
uniprot id: A0A1S6QJU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1138822:PL11 RS06980
gene id: 1138822:PL11_RS06980
uniprot id: A0A1S6QJ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1138822:PL11 RS09655
gene id: 1138822:PL11_RS09655
uniprot id: A0A1S6QKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06795
gene id: 1138822:PL11_RS06795
uniprot id: A0A1S6QJ68
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1138822:PL11 RS10155
gene id: 1138822:PL11_RS10155
uniprot id: A0A1S6QKY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS10130
gene id: 1138822:PL11_RS10130
uniprot id: A0A1S6QKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1138822:PL11 RS03235
gene id: 1138822:PL11_RS03235
uniprot id: A0A1S6QHB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1138822:PL11 RS03125
gene id: 1138822:PL11_RS03125
uniprot id: A0A1S6QH95
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1138822:PL11 RS06410
gene id: 1138822:PL11_RS06410
uniprot id: A0A1S6QIZ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS04990
gene id: 1138822:PL11_RS04990
uniprot id: A0A1S6QI89
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1138822:PL11 RS07135
gene id: 1138822:PL11_RS07135
uniprot id: A0A1S6QJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1138822:PL11 RS03195
gene id: 1138822:PL11_RS03195
uniprot id: A0A1S6QHA4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1138822:PL11 RS01330
gene id: 1138822:PL11_RS01330
uniprot id: A0A1S6QGB6
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1138822:PL11 RS08480
gene id: 1138822:PL11_RS08480
uniprot id: A0A1S6QK38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1138822:PL11 RS02230
gene id: 1138822:PL11_RS02230
uniprot id: A0A1S6QGT0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS05205
gene id: 1138822:PL11_RS05205
uniprot id: A0A1S6QIC7
names: Similarity
messages: Belongs to the universal stress protein A family.

1138822:PL11 RS00465
gene id: 1138822:PL11_RS00465
uniprot id: A0A1S6QFY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1138822:PL11 RS08475
gene id: 1138822:PL11_RS08475
uniprot id: A0A1S6QJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1138822:PL11 RS00705
gene id: 1138822:PL11_RS00705
uniprot id: A0A1S6QG23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1138822:PL11 RS07730
gene id: 1138822:PL11_RS07730
uniprot id: A0A1S6QJP3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1138822:PL11 RS03885
gene id: 1138822:PL11_RS03885
uniprot id: A0A1S6QHQ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1138822:PL11 RS01780
gene id: 1138822:PL11_RS01780
uniprot id: A0A1S6QGJ2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1138822:PL11 RS00825
gene id: 1138822:PL11_RS00825
uniprot id: A0A1S6QG48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09190
gene id: 1138822:PL11_RS09190
uniprot id: A0A1S6QKB3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS02640
gene id: 1138822:PL11_RS02640
uniprot id: A0A1S6QGZ9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1138822:PL11 RS04535
gene id: 1138822:PL11_RS04535
uniprot id: A0A1S6QI26
names: Similarity
messages: Belongs to the TrpC family.

1138822:PL11 RS08710
gene id: 1138822:PL11_RS08710
uniprot id: A0A1S6QK28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1138822:PL11 RS05150
gene id: 1138822:PL11_RS05150
uniprot id: A0A1S6QIA9
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1138822:PL11 RS09470
gene id: 1138822:PL11_RS09470
uniprot id: A0A1S6QKM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS00215
gene id: 1138822:PL11_RS00215
uniprot id: A0A1S6QFV1
names: Similarity
messages: Belongs to the peptidase M20A family.

1138822:PL11 RS04110
gene id: 1138822:PL11_RS04110
uniprot id: A0A1S6QHR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1138822:PL11 RS09530
gene id: 1138822:PL11_RS09530
uniprot id: A0A1S6QKI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1138822:PL11 RS09595
gene id: 1138822:PL11_RS09595
uniprot id: A0A1S6QKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1138822:PL11 RS05010
gene id: 1138822:PL11_RS05010
uniprot id: A0A1S6QI96
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS03795
gene id: 1138822:PL11_RS03795
uniprot id: A0A1S6QHM5
names: Similarity
messages: Belongs to the peptidase C69 family.

1138822:PL11 RS05625
gene id: 1138822:PL11_RS05625
uniprot id: A0A1S6QIK6
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1138822:PL11 RS09880
gene id: 1138822:PL11_RS09880
uniprot id: A0A1S6QKT7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1138822:PL11 RS04815
gene id: 1138822:PL11_RS04815
uniprot id: A0A1S6QI58
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1138822:PL11 RS05400
gene id: 1138822:PL11_RS05400
uniprot id: A0A1S6QIG6
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS04770
gene id: 1138822:PL11_RS04770
uniprot id: A0A1S6QI54
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1138822:PL11 RS03450
gene id: 1138822:PL11_RS03450
uniprot id: A0A1S6QHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1138822:PL11 RS08985
gene id: 1138822:PL11_RS08985
uniprot id: A0A1S6QKC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1138822:PL11 RS06580
gene id: 1138822:PL11_RS06580
uniprot id: A0A1S6QJ46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1138822:PL11 RS09450
gene id: 1138822:PL11_RS09450
uniprot id: A0A1S6QKK6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1138822:PL11 RS02555
gene id: 1138822:PL11_RS02555
uniprot id: A0A1S6QGY2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1138822:PL11 RS01690
gene id: 1138822:PL11_RS01690
uniprot id: A0A1S6QGH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1138822:PL11 RS07150
gene id: 1138822:PL11_RS07150
uniprot id: A0A1S6QJD6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1138822:PL11 RS09275
gene id: 1138822:PL11_RS09275
uniprot id: A0A1S6QKI4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1138822:PL11 RS10185
gene id: 1138822:PL11_RS10185
uniprot id: A0A1S6QKW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1138822:PL11 RS05170
gene id: 1138822:PL11_RS05170
uniprot id: A0A1S6QID4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1138822:PL11 RS03200
gene id: 1138822:PL11_RS03200
uniprot id: A0A1S6QHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02270
gene id: 1138822:PL11_RS02270
uniprot id: A0A1S6QGT1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1138822:PL11 RS02325
gene id: 1138822:PL11_RS02325
uniprot id: A0A1S6QGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS10045
gene id: 1138822:PL11_RS10045
uniprot id: A0A1S6QKV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1138822:PL11 RS08920
gene id: 1138822:PL11_RS08920
uniprot id: A0A1S6QK66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1138822:PL11 RS04095
gene id: 1138822:PL11_RS04095
uniprot id: A0A1S6QHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1138822:PL11 RS00485
gene id: 1138822:PL11_RS00485
uniprot id: A0A1S6QFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1138822:PL11 RS00865
gene id: 1138822:PL11_RS00865
uniprot id: A0A1S6QG50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1138822:PL11 RS02105
gene id: 1138822:PL11_RS02105
uniprot id: A0A1S6QGQ7
names: Similarity
messages: Belongs to the EamA transporter family.

1138822:PL11 RS03820
gene id: 1138822:PL11_RS03820
uniprot id: A0A1S6QHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04455
gene id: 1138822:PL11_RS04455
uniprot id: A0A1S6QHY8
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

1138822:PL11 RS01595
gene id: 1138822:PL11_RS01595
uniprot id: A0A1S6QGH2
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

1138822:PL11 RS06015
gene id: 1138822:PL11_RS06015
uniprot id: A0A1S6QIT0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1138822:PL11 RS08485
gene id: 1138822:PL11_RS08485
uniprot id: A0A1S6QK19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1138822:PL11 RS04885
gene id: 1138822:PL11_RS04885
uniprot id: A0A1S6QI63
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1138822:PL11 RS02545
gene id: 1138822:PL11_RS02545
uniprot id: A0A1S6QGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1138822:PL11 RS06605
gene id: 1138822:PL11_RS06605
uniprot id: A0A1S6QJ26
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1138822:PL11 RS02530
gene id: 1138822:PL11_RS02530
uniprot id: A0A1S6QGY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1138822:PL11 RS09665
gene id: 1138822:PL11_RS09665
uniprot id: A0A1S6QKK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1138822:PL11 RS09080
gene id: 1138822:PL11_RS09080
uniprot id: A0A1S6QKA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1138822:PL11 RS04935
gene id: 1138822:PL11_RS04935
uniprot id: A0A1S6QI74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08820
gene id: 1138822:PL11_RS08820
uniprot id: A0A1S6QK85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1138822:PL11 RS09395
gene id: 1138822:PL11_RS09395
uniprot id: A0A1S6QKI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1138822:PL11 RS06840
gene id: 1138822:PL11_RS06840
uniprot id: A0A1S6QJ54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1138822:PL11 RS07095
gene id: 1138822:PL11_RS07095
uniprot id: A0A1S6QL70
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1138822:PL11 RS03990
gene id: 1138822:PL11_RS03990
uniprot id: A0A1S6QHS3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1138822:PL11 RS08115
gene id: 1138822:PL11_RS08115
uniprot id: A0A1S6QJV1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS09890
gene id: 1138822:PL11_RS09890
uniprot id: A0A1S6QKW4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1138822:PL11 RS04520
gene id: 1138822:PL11_RS04520
uniprot id: A0A1S6QI05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1138822:PL11 RS09325
gene id: 1138822:PL11_RS09325
uniprot id: A0A1S6QKJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1138822:PL11 RS09515
gene id: 1138822:PL11_RS09515
uniprot id: A0A1S6QKL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1138822:PL11 RS03250
gene id: 1138822:PL11_RS03250
uniprot id: A0A1S6QHB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1138822:PL11 RS05230
gene id: 1138822:PL11_RS05230
uniprot id: A0A1S6QL54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1138822:PL11 RS05800
gene id: 1138822:PL11_RS05800
uniprot id: A0A1S6QIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1138822:PL11 RS09905
gene id: 1138822:PL11_RS09905
uniprot id: A0A1S6QKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1138822:PL11 RS07590
gene id: 1138822:PL11_RS07590
uniprot id: A0A1S6QJJ7
names: Similarity
messages: Belongs to the EamA transporter family.

1138822:PL11 RS06755
gene id: 1138822:PL11_RS06755
uniprot id: A0A1S6QJ62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1138822:PL11 RS02895
gene id: 1138822:PL11_RS02895
uniprot id: A0A1S6QH53
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS04895
gene id: 1138822:PL11_RS04895
uniprot id: A0A1S6QI59
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1138822:PL11 RS09540
gene id: 1138822:PL11_RS09540
uniprot id: A0A1S6QKL5
names: Similarity
messages: Belongs to the ribF family.

1138822:PL11 RS08680
gene id: 1138822:PL11_RS08680
uniprot id: A0A1S6QK77
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1138822:PL11 RS06850
gene id: 1138822:PL11_RS06850
uniprot id: A0A1S6QJ79
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1138822:PL11 RS04970
gene id: 1138822:PL11_RS04970
uniprot id: A0A1S6QI87
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS03915
gene id: 1138822:PL11_RS03915
uniprot id: A0A1S6QHP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS07330
gene id: 1138822:PL11_RS07330
uniprot id: A0A1S6QJF5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1138822:PL11 RS06550
gene id: 1138822:PL11_RS06550
uniprot id: A0A1S6QJ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1138822:PL11 RS03185
gene id: 1138822:PL11_RS03185
uniprot id: A0A1S6QH96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08895
gene id: 1138822:PL11_RS08895
uniprot id: A0A1S6QK95
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1138822:PL11 RS08980
gene id: 1138822:PL11_RS08980
uniprot id: A0A1S6QKB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1138822:PL11 RS06330
gene id: 1138822:PL11_RS06330
uniprot id: A0A1S6QIZ0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1138822:PL11 RS07570
gene id: 1138822:PL11_RS07570
uniprot id: A0A1S6QJH4
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS04425
gene id: 1138822:PL11_RS04425
uniprot id: A0A1S6QI06
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1138822:PL11 RS04955
gene id: 1138822:PL11_RS04955
uniprot id: A0A1S6QI85
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1138822:PL11 RS06950
gene id: 1138822:PL11_RS06950
uniprot id: A0A1S6QJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1138822:PL11 RS07790
gene id: 1138822:PL11_RS07790
uniprot id: A0A1S6QJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1138822:PL11 RS10465
gene id: 1138822:PL11_RS10465
uniprot id: A0A1S6QGC8
names: Similarity
messages: Belongs to the peptidase C40 family.

1138822:PL11 RS01490
gene id: 1138822:PL11_RS01490
uniprot id: A0A1S6QGF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1138822:PL11 RS07170
gene id: 1138822:PL11_RS07170
uniprot id: A0A1S6QJD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS06530
gene id: 1138822:PL11_RS06530
uniprot id: A0A1S6QJ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1138822:PL11 RS04615
gene id: 1138822:PL11_RS04615
uniprot id: A0A1S6QI11
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1138822:PL11 RS04865
gene id: 1138822:PL11_RS04865
uniprot id: A0A1S6QI81
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1138822:PL11 RS06570
gene id: 1138822:PL11_RS06570
uniprot id: A0A1S6QJ34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1138822:PL11 RS02830
gene id: 1138822:PL11_RS02830
uniprot id: A0A1S6QH45
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1138822:PL11 RS09775
gene id: 1138822:PL11_RS09775
uniprot id: A0A1S6QKT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1138822:PL11 RS03880
gene id: 1138822:PL11_RS03880
uniprot id: A0A1S6QHM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1138822:PL11 RS01740
gene id: 1138822:PL11_RS01740
uniprot id: A0A1S6QGH9
names: Similarity
messages: Belongs to the EamA transporter family.

1138822:PL11 RS00435
gene id: 1138822:PL11_RS00435
uniprot id: A0A1S6QFW9
names: Similarity
messages: Belongs to the RecJ family.

1138822:PL11 RS08275
gene id: 1138822:PL11_RS08275
uniprot id: A0A1S6QJY5
names: Similarity
messages: Belongs to the UPF0177 family.

1138822:PL11 RS07225
gene id: 1138822:PL11_RS07225
uniprot id: A0A1S6QJD5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06650
gene id: 1138822:PL11_RS06650
uniprot id: A0A1S6QJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1138822:PL11 RS04375
gene id: 1138822:PL11_RS04375
uniprot id: A0A1S6QHZ7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1138822:PL11 RS07070
gene id: 1138822:PL11_RS07070
uniprot id: A0A1S6QJD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1138822:PL11 RS07795
gene id: 1138822:PL11_RS07795
uniprot id: A0A1S6QJN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

1138822:PL11 RS04310
gene id: 1138822:PL11_RS04310
uniprot id: A0A1S6QHV9
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS07060
gene id: 1138822:PL11_RS07060
uniprot id: A0A1S6QJA9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1138822:PL11 RS08525
gene id: 1138822:PL11_RS08525
uniprot id: A0A1S6QK08
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1138822:PL11 RS00930
gene id: 1138822:PL11_RS00930
uniprot id: A0A1S6QG67
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1138822:PL11 RS05080
gene id: 1138822:PL11_RS05080
uniprot id: A0A1S6QIB2
names: Subcellular Location Annotation
messages: Cell membrane

1138822:PL11 RS00140
gene id: 1138822:PL11_RS00140
uniprot id: A0A1S6QFT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09755
gene id: 1138822:PL11_RS09755
uniprot id: A0A1S6QKQ7
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1138822:PL11 RS04255
gene id: 1138822:PL11_RS04255
uniprot id: A0A1S6QHU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1138822:PL11 RS10025
gene id: 1138822:PL11_RS10025
uniprot id: A0A1S6QKY2
names: Similarity
messages: Belongs to the universal stress protein A family.

1138822:PL11 RS01520
gene id: 1138822:PL11_RS01520
uniprot id: A0A1S6QGF5
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1138822:PL11 RS03430
gene id: 1138822:PL11_RS03430
uniprot id: A0A1S6QHF4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1138822:PL11 RS02960
gene id: 1138822:PL11_RS02960
uniprot id: A0A1S6QH58
names: Similarity
messages: Belongs to the carbamate kinase family.

1138822:PL11 RS09390
gene id: 1138822:PL11_RS09390
uniprot id: A0A1S6QKI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1138822:PL11 RS03325
gene id: 1138822:PL11_RS03325
uniprot id: A0A1S6QHD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1138822:PL11 RS00165
gene id: 1138822:PL11_RS00165
uniprot id: A0A1S6QFU0
names: Similarity
messages: Belongs to the TPP enzyme family.

1138822:PL11 RS03605
gene id: 1138822:PL11_RS03605
uniprot id: A0A1S6QHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1138822:PL11 RS08620
gene id: 1138822:PL11_RS08620
uniprot id: A0A1S6QK36
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1138822:PL11 RS00470
gene id: 1138822:PL11_RS00470
uniprot id: A0A1S6QFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1138822:PL11 RS04510
gene id: 1138822:PL11_RS04510
uniprot id: A0A1S6QHZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04305
gene id: 1138822:PL11_RS04305
uniprot id: A0A1S6QHV4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1138822:PL11 RS00810
gene id: 1138822:PL11_RS00810
uniprot id: A0A1S6QG38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1138822:PL11 RS08625
gene id: 1138822:PL11_RS08625
uniprot id: A0A1S6QK24
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1138822:PL11 RS08855
gene id: 1138822:PL11_RS08855
uniprot id: A0A1S6QKA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1138822:PL11 RS07770
gene id: 1138822:PL11_RS07770
uniprot id: A0A1S6QJN7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1138822:PL11 RS08510
gene id: 1138822:PL11_RS08510
uniprot id: A0A1S6QK31
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS07280
gene id: 1138822:PL11_RS07280
uniprot id: A0A1S6QJE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS10115
gene id: 1138822:PL11_RS10115
uniprot id: A0A1S6QKW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1138822:PL11 RS03360
gene id: 1138822:PL11_RS03360
uniprot id: A0A1S6QHE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04130
gene id: 1138822:PL11_RS04130
uniprot id: A0A1S6QHT8
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS02800
gene id: 1138822:PL11_RS02800
uniprot id: A0A1S6QH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1138822:PL11 RS09700
gene id: 1138822:PL11_RS09700
uniprot id: A0A1S6QKN3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1138822:PL11 RS03530
gene id: 1138822:PL11_RS03530
uniprot id: A0A1S6QHH1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09075
gene id: 1138822:PL11_RS09075
uniprot id: A0A1S6QK92
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1138822:PL11 RS00675
gene id: 1138822:PL11_RS00675
uniprot id: A0A1S6QG16
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1138822:PL11 RS08960
gene id: 1138822:PL11_RS08960
uniprot id: A0A1S6QK97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1138822:PL11 RS09250
gene id: 1138822:PL11_RS09250
uniprot id: A0A1S6QKC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS06810
gene id: 1138822:PL11_RS06810
uniprot id: A0A1S6QJ93
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1138822:PL11 RS07175
gene id: 1138822:PL11_RS07175
uniprot id: A0A1S6QJC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1138822:PL11 RS00670
gene id: 1138822:PL11_RS00670
uniprot id: A0A1S6QG22
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved.

1138822:PL11 RS02370
gene id: 1138822:PL11_RS02370
uniprot id: A0A1S6QGU7
names: Similarity
messages: Belongs to the peptidase C59 family.

1138822:PL11 RS08300
gene id: 1138822:PL11_RS08300
uniprot id: A0A1S6QJY0
names: Similarity
messages: Belongs to the peptidase C40 family.

1138822:PL11 RS05075
gene id: 1138822:PL11_RS05075
uniprot id: A0A1S6QIB7
names: Similarity
messages: Belongs to the ThiD family.

1138822:PL11 RS09950
gene id: 1138822:PL11_RS09950
uniprot id: A0A1S6QKT9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1138822:PL11 RS01060
gene id: 1138822:PL11_RS01060
uniprot id: A0A1S6QG69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS01680
gene id: 1138822:PL11_RS01680
uniprot id: A0A1S6QL15
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1138822:PL11 RS01970
gene id: 1138822:PL11_RS01970
uniprot id: A0A1S6QGL7
names: Similarity
messages: Belongs to the UPF0177 family.

1138822:PL11 RS09710
gene id: 1138822:PL11_RS09710
uniprot id: A0A1S6QKP4
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS08950
gene id: 1138822:PL11_RS08950
uniprot id: A0A1S6QL69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1138822:PL11 RS02560
gene id: 1138822:PL11_RS02560
uniprot id: A0A1S6QGZ4
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS03540
gene id: 1138822:PL11_RS03540
uniprot id: A0A1S6QHG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS07875
gene id: 1138822:PL11_RS07875
uniprot id: A0A1S6QJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1138822:PL11 RS08945
gene id: 1138822:PL11_RS08945
uniprot id: A0A1S6QKD2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1138822:PL11 RS04525
gene id: 1138822:PL11_RS04525
uniprot id: A0A1S6QI03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1138822:PL11 RS06155
gene id: 1138822:PL11_RS06155
uniprot id: A0A1S6QIV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1138822:PL11 RS07105
gene id: 1138822:PL11_RS07105
uniprot id: A0A1S6QL72
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1138822:PL11 RS07255
gene id: 1138822:PL11_RS07255
uniprot id: A0A1S6QJB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1138822:PL11 RS03275
gene id: 1138822:PL11_RS03275
uniprot id: A0A1S6QHC5
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS09615
gene id: 1138822:PL11_RS09615
uniprot id: A0A1S6QKK2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS08005
gene id: 1138822:PL11_RS08005
uniprot id: A0A1S6QJT1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1138822:PL11 RS05480
gene id: 1138822:PL11_RS05480
uniprot id: A0A1S6QII3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

1138822:PL11 RS05420
gene id: 1138822:PL11_RS05420
uniprot id: A0A1S6QIG5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1138822:PL11 RS07870
gene id: 1138822:PL11_RS07870
uniprot id: A0A1S6QJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1138822:PL11 RS00275
gene id: 1138822:PL11_RS00275
uniprot id: A0A1S6QFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04270
gene id: 1138822:PL11_RS04270
uniprot id: A0A1S6QHY0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1138822:PL11 RS08990
gene id: 1138822:PL11_RS08990
uniprot id: A0A1S6QKA4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1138822:PL11 RS03230
gene id: 1138822:PL11_RS03230
uniprot id: A0A1S6QHB0
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1138822:PL11 RS02090
gene id: 1138822:PL11_RS02090
uniprot id: A0A1S6QGQ2
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS09585
gene id: 1138822:PL11_RS09585
uniprot id: A0A1S6QKJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS02520
gene id: 1138822:PL11_RS02520
uniprot id: A0A1S6QGY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1138822:PL11 RS08230
gene id: 1138822:PL11_RS08230
uniprot id: A0A1S6QJT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1138822:PL11 RS07685
gene id: 1138822:PL11_RS07685
uniprot id: A0A1S6QJL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1138822:PL11 RS08975
gene id: 1138822:PL11_RS08975
uniprot id: A0A1S6QK75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1138822:PL11 RS06595
gene id: 1138822:PL11_RS06595
uniprot id: A0A1S6QJ35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1138822:PL11 RS08010
gene id: 1138822:PL11_RS08010
uniprot id: A0A1S6QJS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1138822:PL11 RS00615
gene id: 1138822:PL11_RS00615
uniprot id: A0A1S6QG13
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1138822:PL11 RS01695
gene id: 1138822:PL11_RS01695
uniprot id: A0A1S6QGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1138822:PL11 RS04920
gene id: 1138822:PL11_RS04920
uniprot id: A0A1S6QI79
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS07850
gene id: 1138822:PL11_RS07850
uniprot id: A0A1S6QJP4
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS06975
gene id: 1138822:PL11_RS06975
uniprot id: A0A1S6QJA0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1138822:PL11 RS10170
gene id: 1138822:PL11_RS10170
uniprot id: A0A1S6QKZ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1138822:PL11 RS06150
gene id: 1138822:PL11_RS06150
uniprot id: A0A1S6QIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS04940
gene id: 1138822:PL11_RS04940
uniprot id: A0A1S6QI77
names: Function
names: Similarity
messages: Belongs to the aldose epimerase family.
messages: Catalyzes the interconversion of alpha and beta anomers of maltose.

1138822:PL11 RS06115
gene id: 1138822:PL11_RS06115
uniprot id: A0A1S6QIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS05615
gene id: 1138822:PL11_RS05615
uniprot id: A0A1S6QIL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02335
gene id: 1138822:PL11_RS02335
uniprot id: A0A1S6QGV0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1138822:PL11 RS07250
gene id: 1138822:PL11_RS07250
uniprot id: A0A1S6QJF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1138822:PL11 RS00530
gene id: 1138822:PL11_RS00530
uniprot id: A0A1S6QFY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1138822:PL11 RS07410
gene id: 1138822:PL11_RS07410
uniprot id: A0A1S6QJD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1138822:PL11 RS01665
gene id: 1138822:PL11_RS01665
uniprot id: A0A1S6QGH5
names: Similarity
messages: Belongs to the ParB family.

1138822:PL11 RS03700
gene id: 1138822:PL11_RS03700
uniprot id: A0A1S6QHJ4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1138822:PL11 RS09215
gene id: 1138822:PL11_RS09215
uniprot id: A0A1S6QKC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1138822:PL11 RS07855
gene id: 1138822:PL11_RS07855
uniprot id: A0A1S6QJP2
names: Similarity
messages: Belongs to the IMPACT family.

1138822:PL11 RS06790
gene id: 1138822:PL11_RS06790
uniprot id: A0A1S6QJ85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1138822:PL11 RS00780
gene id: 1138822:PL11_RS00780
uniprot id: A0A1S6QG41
names: Subcellular Location Annotation
messages: Cytoplasm

1138822:PL11 RS05295
gene id: 1138822:PL11_RS05295
uniprot id: A0A1S6QIF2
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

1138822:PL11 RS04645
gene id: 1138822:PL11_RS04645
uniprot id: A0A1S6QI30
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1138822:PL11 RS03460
gene id: 1138822:PL11_RS03460
uniprot id: A0A1S6QHG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02345
gene id: 1138822:PL11_RS02345
uniprot id: A0A1S6QGV6
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS00730
gene id: 1138822:PL11_RS00730
uniprot id: A0A1S6QG34
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1138822:PL11 RS04760
gene id: 1138822:PL11_RS04760
uniprot id: A0A1S6QI62
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1138822:PL11 RS09970
gene id: 1138822:PL11_RS09970
uniprot id: A0A1S6QKV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1138822:PL11 RS08875
gene id: 1138822:PL11_RS08875
uniprot id: A0A1S6QKA8
names: Similarity
messages: Belongs to the asp23 family.

1138822:PL11 RS02135
gene id: 1138822:PL11_RS02135
uniprot id: A0A1S6QGR4
names: Similarity
messages: Belongs to the ThiD family.

1138822:PL11 RS06495
gene id: 1138822:PL11_RS06495
uniprot id: A0A401FLM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1138822:PL11 RS10125
gene id: 1138822:PL11_RS10125
uniprot id: A0A1S6QL03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1138822:PL11 RS05445
gene id: 1138822:PL11_RS05445
uniprot id: A0A1S6QII7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08955
gene id: 1138822:PL11_RS08955
uniprot id: A0A1S6QKB1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1138822:PL11 RS02085
gene id: 1138822:PL11_RS02085
uniprot id: A0A1S6QGP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS07565
gene id: 1138822:PL11_RS07565
uniprot id: A0A1S6QJK2
names: Subcellular Location Annotation
messages: Cytoplasm

1138822:PL11 RS07830
gene id: 1138822:PL11_RS07830
uniprot id: A0A1S6QJL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1138822:PL11 RS03180
gene id: 1138822:PL11_RS03180
uniprot id: A0A1S6QHA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08070
gene id: 1138822:PL11_RS08070
uniprot id: A0A1S6QJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1138822:PL11 RS09550
gene id: 1138822:PL11_RS09550
uniprot id: A0A1S6QKL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1138822:PL11 RS08995
gene id: 1138822:PL11_RS08995
uniprot id: A0A1S6QK91
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS01675
gene id: 1138822:PL11_RS01675
uniprot id: A0A1S6QGJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1138822:PL11 RS00665
gene id: 1138822:PL11_RS00665
uniprot id: A0A1S6QKY6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1138822:PL11 RS01160
gene id: 1138822:PL11_RS01160
uniprot id: A0A1S6QG79
names: Similarity
messages: Belongs to the peptidase S11 family.

1138822:PL11 RS10015
gene id: 1138822:PL11_RS10015
uniprot id: A0A1S6QKU0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1138822:PL11 RS06280
gene id: 1138822:PL11_RS06280
uniprot id: A0A1S6QIX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS02305
gene id: 1138822:PL11_RS02305
uniprot id: A0A1S6QGT8
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS00600
gene id: 1138822:PL11_RS00600
uniprot id: A0A1S6QG11
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1138822:PL11 RS05935
gene id: 1138822:PL11_RS05935
uniprot id: A0A1S6QIR8
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS09085
gene id: 1138822:PL11_RS09085
uniprot id: A0A1S6QKE0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1138822:PL11 RS08035
gene id: 1138822:PL11_RS08035
uniprot id: A0A1S6QJT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1138822:PL11 RS00560
gene id: 1138822:PL11_RS00560
uniprot id: A0A1S6QG05
names: Similarity
messages: Belongs to the peptidase S16 family.

1138822:PL11 RS08520
gene id: 1138822:PL11_RS08520
uniprot id: A0A1S6QK16
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1138822:PL11 RS07980
gene id: 1138822:PL11_RS07980
uniprot id: A0A1S6QJT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1138822:PL11 RS06575
gene id: 1138822:PL11_RS06575
uniprot id: A0A1S6QJ30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1138822:PL11 RS07630
gene id: 1138822:PL11_RS07630
uniprot id: A0A1S6QJM6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1138822:PL11 RS02140
gene id: 1138822:PL11_RS02140
uniprot id: A0A1S6QGR6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1138822:PL11 RS07755
gene id: 1138822:PL11_RS07755
uniprot id: A0A1S6QJQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1138822:PL11 RS06175
gene id: 1138822:PL11_RS06175
uniprot id: A0A1S6QIW4
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS01475
gene id: 1138822:PL11_RS01475
uniprot id: A0A1S6QGD0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS01265
gene id: 1138822:PL11_RS01265
uniprot id: A0A1S6QGA7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 8 family.

1138822:PL11 RS03315
gene id: 1138822:PL11_RS03315
uniprot id: A0A1S6QL11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS05960
gene id: 1138822:PL11_RS05960
uniprot id: A0A1S6QIS4
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS05200
gene id: 1138822:PL11_RS05200
uniprot id: A0A1S6QIB9
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1138822:PL11 RS03390
gene id: 1138822:PL11_RS03390
uniprot id: A0A1S6QHE6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1138822:PL11 RS03830
gene id: 1138822:PL11_RS03830
uniprot id: A0A1S6QHP5
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS08885
gene id: 1138822:PL11_RS08885
uniprot id: A0A1S6QK73
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1138822:PL11 RS01125
gene id: 1138822:PL11_RS01125
uniprot id: A0A1S6QG84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1138822:PL11 RS08655
gene id: 1138822:PL11_RS08655
uniprot id: A0A1S6QK22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08835
gene id: 1138822:PL11_RS08835
uniprot id: A0A1S6QK62
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1138822:PL11 RS00710
gene id: 1138822:PL11_RS00710
uniprot id: A0A1S6QG29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1138822:PL11 RS10180
gene id: 1138822:PL11_RS10180
uniprot id: A0A1S6QKZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1138822:PL11 RS02200
gene id: 1138822:PL11_RS02200
uniprot id: A0A1S6QGR9
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS03760
gene id: 1138822:PL11_RS03760
uniprot id: A0A1S6QHK8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS07625
gene id: 1138822:PL11_RS07625
uniprot id: A0A1S6QJI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1138822:PL11 RS07520
gene id: 1138822:PL11_RS07520
uniprot id: A0A1S6QJG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1138822:PL11 RS10120
gene id: 1138822:PL11_RS10120
uniprot id: A0A1S6QKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1138822:PL11 RS03955
gene id: 1138822:PL11_RS03955
uniprot id: A0A1S6QHQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1138822:PL11 RS00230
gene id: 1138822:PL11_RS00230
uniprot id: A0A1S6QFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1138822:PL11 RS07595
gene id: 1138822:PL11_RS07595
uniprot id: A0A1S6QJJ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS06085
gene id: 1138822:PL11_RS06085
uniprot id: A0A1S6QIT6
names: Similarity
messages: Belongs to the peptidase M20A family.

1138822:PL11 RS03595
gene id: 1138822:PL11_RS03595
uniprot id: A0A1S6QHI5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1138822:PL11 RS08280
gene id: 1138822:PL11_RS08280
uniprot id: A0A1S6QJU3
names: Similarity
messages: Belongs to the peptidase S58 family.

1138822:PL11 RS04550
gene id: 1138822:PL11_RS04550
uniprot id: A0A1S6QI08
names: Similarity
messages: Belongs to the peptidase C69 family.

1138822:PL11 RS09825
gene id: 1138822:PL11_RS09825
uniprot id: A0A1S6QKU5
names: Similarity
messages: Belongs to the UPF0473 family.

1138822:PL11 RS06245
gene id: 1138822:PL11_RS06245
uniprot id: A0A1S6QIX1
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS06540
gene id: 1138822:PL11_RS06540
uniprot id: A0A1S6QJ21
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1138822:PL11 RS01115
gene id: 1138822:PL11_RS01115
uniprot id: A0A1S6QG78
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1138822:PL11 RS03080
gene id: 1138822:PL11_RS03080
uniprot id: A0A1S6QH69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS05565
gene id: 1138822:PL11_RS05565
uniprot id: A0A1S6QIJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1138822:PL11 RS05240
gene id: 1138822:PL11_RS05240
uniprot id: A0A1S6QID3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1138822:PL11 RS04605
gene id: 1138822:PL11_RS04605
uniprot id: A0A1S6QI13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1138822:PL11 RS06455
gene id: 1138822:PL11_RS06455
uniprot id: A0A1S6QIZ5
names: Similarity
messages: Belongs to the CtsR family.

1138822:PL11 RS07705
gene id: 1138822:PL11_RS07705
uniprot id: A0A1S6QJM5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1138822:PL11 RS09740
gene id: 1138822:PL11_RS09740
uniprot id: A0A1S6QKT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1138822:PL11 RS00050
gene id: 1138822:PL11_RS00050
uniprot id: A0A1S6QFR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS02610
gene id: 1138822:PL11_RS02610
uniprot id: A0A1S6QGZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1138822:PL11 RS04140
gene id: 1138822:PL11_RS04140
uniprot id: A0A1S6QHT4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS08175
gene id: 1138822:PL11_RS08175
uniprot id: A0A1S6QJS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1138822:PL11 RS03650
gene id: 1138822:PL11_RS03650
uniprot id: A0A1S6QHI1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1138822:PL11 RS01130
gene id: 1138822:PL11_RS01130
uniprot id: A0A1S6QG83
names: Similarity
messages: Belongs to the UPF0177 family.

1138822:PL11 RS00565
gene id: 1138822:PL11_RS00565
uniprot id: A0A1S6QG03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1138822:PL11 RS01190
gene id: 1138822:PL11_RS01190
uniprot id: A0A1S6QG92
names: Similarity
messages: Belongs to the TPP enzyme family.

1138822:PL11 RS05285
gene id: 1138822:PL11_RS05285
uniprot id: A0A1S6QIF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1138822:PL11 RS06090
gene id: 1138822:PL11_RS06090
uniprot id: A0A1S6QIV6
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS04285
gene id: 1138822:PL11_RS04285
uniprot id: A0A1S6QHV5
names: Similarity
messages: Belongs to the UPF0735 family.

1138822:PL11 RS09225
gene id: 1138822:PL11_RS09225
uniprot id: A0A1S6QKF8
names: Similarity
messages: Belongs to the UPF0346 family.

1138822:PL11 RS07320
gene id: 1138822:PL11_RS07320
uniprot id: A0A1S6QJH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1138822:PL11 RS03220
gene id: 1138822:PL11_RS03220
uniprot id: A0A1S6QL36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09570
gene id: 1138822:PL11_RS09570
uniprot id: A0A1S6QKP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1138822:PL11 RS09875
gene id: 1138822:PL11_RS09875
uniprot id: A0A1S6QKV0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1138822:PL11 RS07415
gene id: 1138822:PL11_RS07415
uniprot id: A0A1S6QJI5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1138822:PL11 RS01180
gene id: 1138822:PL11_RS01180
uniprot id: A0A1S6QG94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08900
gene id: 1138822:PL11_RS08900
uniprot id: A0A1S6QK88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1138822:PL11 RS08360
gene id: 1138822:PL11_RS08360
uniprot id: A0A1S6QL91
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS06865
gene id: 1138822:PL11_RS06865
uniprot id: A0A1S6QJA3
names: Similarity
messages: Belongs to the FGGY kinase family.

1138822:PL11 RS01565
gene id: 1138822:PL11_RS01565
uniprot id: A0A1S6QGF6
names: Similarity
messages: Belongs to the XFP family.

1138822:PL11 RS04300
gene id: 1138822:PL11_RS04300
uniprot id: A0A1S6QHW1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1138822:PL11 RS01545
gene id: 1138822:PL11_RS01545
uniprot id: A0A1S6QGG2
names: Similarity
messages: Belongs to the UPF0246 family.

1138822:PL11 RS03630
gene id: 1138822:PL11_RS03630
uniprot id: A0A1S6QHJ0
names: Similarity
messages: Belongs to the PRORSD1 family.

1138822:PL11 RS02535
gene id: 1138822:PL11_RS02535
uniprot id: A0A1S6QGX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1138822:PL11 RS08580
gene id: 1138822:PL11_RS08580
uniprot id: A0A1S6QK55
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1138822:PL11 RS02975
gene id: 1138822:PL11_RS02975
uniprot id: A0A1S6QH48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. PTCase family.
messages: Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine. Is involved in the degradation pathway of the polyamine agmatine.
messages: Cytoplasm
messages: Homotrimer.

1138822:PL11 RS08370
gene id: 1138822:PL11_RS08370
uniprot id: A0A1S6QJX5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1138822:PL11 RS03695
gene id: 1138822:PL11_RS03695
uniprot id: A0A1S6QHK5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1138822:PL11 RS03120
gene id: 1138822:PL11_RS03120
uniprot id: A0A1S6QH92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1138822:PL11 RS09525
gene id: 1138822:PL11_RS09525
uniprot id: A0A1S6QKK9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1138822:PL11 RS00175
gene id: 1138822:PL11_RS00175
uniprot id: A0A1S6QFT5
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1138822:PL11 RS08210
gene id: 1138822:PL11_RS08210
uniprot id: A0A1S6QJY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS00130
gene id: 1138822:PL11_RS00130
uniprot id: A0A1S6QKW6
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1138822:PL11 RS02290
gene id: 1138822:PL11_RS02290
uniprot id: A0A1S6QGU5
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1138822:PL11 RS03335
gene id: 1138822:PL11_RS03335
uniprot id: A0A1S6QHC8
names: Similarity
messages: Belongs to the EamA transporter family.

1138822:PL11 RS04665
gene id: 1138822:PL11_RS04665
uniprot id: A0A1S6QI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1138822:PL11 RS05105
gene id: 1138822:PL11_RS05105
uniprot id: A0A1S6QIA8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1138822:PL11 RS06985
gene id: 1138822:PL11_RS06985
uniprot id: A0A1S6QJ98
names: Similarity
messages: Belongs to the peptidase C69 family.

1138822:PL11 RS05140
gene id: 1138822:PL11_RS05140
uniprot id: A0A1S6QIB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS00870
gene id: 1138822:PL11_RS00870
uniprot id: A0A1S6QG54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS04595
gene id: 1138822:PL11_RS04595
uniprot id: A0A1S6QI21
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS03560
gene id: 1138822:PL11_RS03560
uniprot id: A0A1S6QHH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1138822:PL11 RS04275
gene id: 1138822:PL11_RS04275
uniprot id: A0A1S6QHW2
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS10135
gene id: 1138822:PL11_RS10135
uniprot id: A0A1S6QKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1138822:PL11 RS05060
gene id: 1138822:PL11_RS05060
uniprot id: A0A1S6QIA6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1138822:PL11 RS09155
gene id: 1138822:PL11_RS09155
uniprot id: A0A1S6QKF5
names: Caution
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS08760
gene id: 1138822:PL11_RS08760
uniprot id: A0A1S6QK32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1138822:PL11 RS05300
gene id: 1138822:PL11_RS05300
uniprot id: A0A1S6QIE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1138822:PL11 RS03210
gene id: 1138822:PL11_RS03210
uniprot id: A0A1S6QHB1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1138822:PL11 RS06220
gene id: 1138822:PL11_RS06220
uniprot id: A0A1S6QIY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS06750
gene id: 1138822:PL11_RS06750
uniprot id: A0A1S6QJ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1138822:PL11 RS06765
gene id: 1138822:PL11_RS06765
uniprot id: A0A1S6QJ61
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1138822:PL11 RS03535
gene id: 1138822:PL11_RS03535
uniprot id: A0A1S6QHH4
names: Similarity
messages: Belongs to the universal stress protein A family.

1138822:PL11 RS09125
gene id: 1138822:PL11_RS09125
uniprot id: A0A1S6QKF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1138822:PL11 RS04085
gene id: 1138822:PL11_RS04085
uniprot id: A0A1S6QHS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1138822:PL11 RS09485
gene id: 1138822:PL11_RS09485
uniprot id: A0A1S6QKN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1138822:PL11 RS08635
gene id: 1138822:PL11_RS08635
uniprot id: A0A1S6QK46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1138822:PL11 RS06395
gene id: 1138822:PL11_RS06395
uniprot id: A0A1S6QJ00
names: Subcellular Location Annotation
messages: Membrane

1138822:PL11 RS04465
gene id: 1138822:PL11_RS04465
uniprot id: A0A1S6QHY1
names: Similarity
messages: Belongs to the UPF0340 family.

1138822:PL11 RS01185
gene id: 1138822:PL11_RS01185
uniprot id: A0A1S6QG90
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1138822:PL11 RS02735
gene id: 1138822:PL11_RS02735
uniprot id: A0A1S6QH20
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06120
gene id: 1138822:PL11_RS06120
uniprot id: A0A1S6QIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS06770
gene id: 1138822:PL11_RS06770
uniprot id: A0A1S6QJ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1138822:PL11 RS04600
gene id: 1138822:PL11_RS04600
uniprot id: A0A1S6QI17
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 2 subfamily.
messages: Heterodimer of AddA and RexB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' -> 3' nuclease activity.

1138822:PL11 RS10060
gene id: 1138822:PL11_RS10060
uniprot id: A0A1S6QKT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS09575
gene id: 1138822:PL11_RS09575
uniprot id: A0A1S6QKM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1138822:PL11 RS02395
gene id: 1138822:PL11_RS02395
uniprot id: A0A1S6QGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1138822:PL11 RS00845
gene id: 1138822:PL11_RS00845
uniprot id: A0A1S6QG46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1138822:PL11 RS03145
gene id: 1138822:PL11_RS03145
uniprot id: A0A1S6QH94
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS07665
gene id: 1138822:PL11_RS07665
uniprot id: A0A1S6QJM3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1138822:PL11 RS06205
gene id: 1138822:PL11_RS06205
uniprot id: A0A1S6QIW8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1138822:PL11 RS09345
gene id: 1138822:PL11_RS09345
uniprot id: A0A1S6QKE3
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1138822:PL11 RS02175
gene id: 1138822:PL11_RS02175
uniprot id: A0A1S6QGS3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1138822:PL11 RS00840
gene id: 1138822:PL11_RS00840
uniprot id: A0A1S6QG51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1138822:PL11 RS07925
gene id: 1138822:PL11_RS07925
uniprot id: A0A1S6QJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1138822:PL11 RS07760
gene id: 1138822:PL11_RS07760
uniprot id: A0A1S6QJN4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1138822:PL11 RS06020
gene id: 1138822:PL11_RS06020
uniprot id: A0A1S6QIT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1138822:PL11 RS08050
gene id: 1138822:PL11_RS08050
uniprot id: A0A1S6QJQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1138822:PL11 RS03680
gene id: 1138822:PL11_RS03680
uniprot id: A0A1S6QHK0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1138822:PL11 RS09495
gene id: 1138822:PL11_RS09495
uniprot id: A0A1S6QKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1138822:PL11 RS04080
gene id: 1138822:PL11_RS04080
uniprot id: A0A1S6QHR9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1138822:PL11 RS07750
gene id: 1138822:PL11_RS07750
uniprot id: A0A1S6QJM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1138822:PL11 RS05855
gene id: 1138822:PL11_RS05855
uniprot id: A0A1S6QIP5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1138822:PL11 RS08860
gene id: 1138822:PL11_RS08860
uniprot id: A0A1S6QK51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.