1136231:CORT 0H02710
gene id: 1136231:CORT_0H02710
uniprot id: H8XBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1136231:CORT 0F01730
gene id: 1136231:CORT_0F01730
uniprot id: H8X9A1
names: Similarity
messages: Belongs to the dopey family.

1136231:CORT 0D01420
gene id: 1136231:CORT_0D01420
uniprot id: H8X4P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

1136231:CORT 0A05500
gene id: 1136231:CORT_0A05500
uniprot id: H8WXZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

1136231:CORT 0A09820
gene id: 1136231:CORT_0A09820
uniprot id: H8WX62
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

1136231:CORT 0E03840
gene id: 1136231:CORT_0E03840
uniprot id: H8X743
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B07030
gene id: 1136231:CORT_0B07030
uniprot id: H8X1K5
names: Similarity
messages: Belongs to the MGR2 family.

1136231:CORT 0E02980
gene id: 1136231:CORT_0E02980
uniprot id: H8X7V1
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1136231:CORT 0C04430
gene id: 1136231:CORT_0C04430
uniprot id: H8X2V6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

1136231:CORT 0G00440
gene id: 1136231:CORT_0G00440
uniprot id: H8X9R8
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

1136231:CORT 0E02920
gene id: 1136231:CORT_0E02920
uniprot id: H8X7U4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B08840
gene id: 1136231:CORT_0B08840
uniprot id: H8X076
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1136231:CORT 0A02640
gene id: 1136231:CORT_0A02640
uniprot id: H8WW31
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

1136231:CORT 0A12280
gene id: 1136231:CORT_0A12280
uniprot id: H8WYY1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136231:CORT 0F00550
gene id: 1136231:CORT_0F00550
uniprot id: H8X8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0B11480
gene id: 1136231:CORT_0B11480
uniprot id: H8X2C5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1136231:CORT 0A06360
gene id: 1136231:CORT_0A06360
uniprot id: H8WWN3
names: Similarity
messages: Belongs to the enolase family.

1136231:CORT 0B00130
gene id: 1136231:CORT_0B00130
uniprot id: H8WZ68
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1136231:CORT 0A09170
gene id: 1136231:CORT_0A09170
uniprot id: H8WYI6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1136231:CORT 0E05430
gene id: 1136231:CORT_0E05430
uniprot id: H8X829
names: Subcellular Location Annotation
messages: Peroxisome membrane

1136231:CORT 0D07390
gene id: 1136231:CORT_0D07390
uniprot id: H8X6G1
names: Similarity
messages: Belongs to the VPS8 family.

1136231:CORT 0A10990
gene id: 1136231:CORT_0A10990
uniprot id: H8WXH8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

1136231:CORT 0C06710
gene id: 1136231:CORT_0C06710
uniprot id: H8X491
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1136231:CORT 0H00780
gene id: 1136231:CORT_0H00780
uniprot id: H8XBK7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A01930
gene id: 1136231:CORT_0A01930
uniprot id: H8WVW0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

1136231:CORT 0E00290
gene id: 1136231:CORT_0E00290
uniprot id: H8X6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

1136231:CORT 0B01860
gene id: 1136231:CORT_0B01860
uniprot id: H8X0L5
names: Similarity
messages: Belongs to the lysophospholipase family.

1136231:CORT 0A03120
gene id: 1136231:CORT_0A03120
uniprot id: H8WW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1136231:CORT 0F02340
gene id: 1136231:CORT_0F02340
uniprot id: H8X8I4
names: Function
names: Subcellular Location Annotation
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion

1136231:CORT 0B01490
gene id: 1136231:CORT_0B01490
uniprot id: H8WZK0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1136231:CORT 0E00540
gene id: 1136231:CORT_0E00540
uniprot id: H8X6N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

1136231:CORT 0F02300
gene id: 1136231:CORT_0F02300
uniprot id: H8X8I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.

1136231:CORT 0F03880
gene id: 1136231:CORT_0F03880
uniprot id: H8X9E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

1136231:CORT 0B05170
gene id: 1136231:CORT_0B05170
uniprot id: H8WZN0
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

1136231:CORT 0G02340
gene id: 1136231:CORT_0G02340
uniprot id: H8XAR4
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1136231:CORT 0F02200
gene id: 1136231:CORT_0F02200
uniprot id: H8X8H0
names: Function
names: Similarity
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

1136231:CORT 0E05750
gene id: 1136231:CORT_0E05750
uniprot id: H8X860
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D03090
gene id: 1136231:CORT_0D03090
uniprot id: H8X561
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: spindle

1136231:CORT 0A07520
gene id: 1136231:CORT_0A07520
uniprot id: H8WWZ8
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B04110
gene id: 1136231:CORT_0B04110
uniprot id: H8X178
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

1136231:CORT 0A08990
gene id: 1136231:CORT_0A08990
uniprot id: H8WYG8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

1136231:CORT 0A04430
gene id: 1136231:CORT_0A04430
uniprot id: H8WWK7
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1136231:CORT 0B07200
gene id: 1136231:CORT_0B07200
uniprot id: H8X1M2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1136231:CORT 0F00620
gene id: 1136231:CORT_0F00620
uniprot id: H8X8Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

1136231:CORT 0B07730
gene id: 1136231:CORT_0B07730
uniprot id: H8X1S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOS1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: SNARE required for protein transport between the ER and the Golgi complex.

1136231:CORT 0C06180
gene id: 1136231:CORT_0C06180
uniprot id: H8X439
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

1136231:CORT 0B09250
gene id: 1136231:CORT_0B09250
uniprot id: H8X0B7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F00460
gene id: 1136231:CORT_0F00460
uniprot id: H8X8X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

1136231:CORT 0A13380
gene id: 1136231:CORT_0A13380
uniprot id: H8WXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1136231:CORT 0C00560
gene id: 1136231:CORT_0C00560
uniprot id: H8X3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

1136231:CORT 0B06190
gene id: 1136231:CORT_0B06190
uniprot id: H8WZY3
names: Similarity
messages: Belongs to the IUNH family.

1136231:CORT 0B09640
gene id: 1136231:CORT_0B09640
uniprot id: H8X0F6
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

1136231:CORT 0B10470
gene id: 1136231:CORT_0B10470
uniprot id: H8X228
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

1136231:CORT 0G01050
gene id: 1136231:CORT_0G01050
uniprot id: H8X9X6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B10480
gene id: 1136231:CORT_0B10480
uniprot id: H8X229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1136231:CORT 0H00440
gene id: 1136231:CORT_0H00440
uniprot id: H8XBH3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1136231:CORT 0G01240
gene id: 1136231:CORT_0G01240
uniprot id: H8XAG2
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

1136231:CORT 0B00840
gene id: 1136231:CORT_0B00840
uniprot id: H8WZD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

1136231:CORT 0D06370
gene id: 1136231:CORT_0D06370
uniprot id: H8X5L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0F03060
gene id: 1136231:CORT_0F03060
uniprot id: H8X8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

1136231:CORT 0B04360
gene id: 1136231:CORT_0B04360
uniprot id: H8X1A3
names: Similarity
messages: Belongs to the sulfatase family.

1136231:CORT 0B05620
gene id: 1136231:CORT_0B05620
uniprot id: H8WZS5
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1136231:CORT 0A10220
gene id: 1136231:CORT_0A10220
uniprot id: H8WXA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

1136231:CORT 0G01840
gene id: 1136231:CORT_0G01840
uniprot id: H8XAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Involved in the maintenance of ribosomal (rDNA). Required for efficient fork arrest at the replicaion fork barrier within rDNA. Involved in the maintenance of mitochondrial (mtDNA). Required to maintain mtDNA under conditions that introduce dsDNA breaks in mtDNA, either preventing or repairing dsDNA breaks. May inhibit replication progression to allow time for repair. May have a general role in chromosomal replication by affecting Okazaki fragment maturation. May have a role in conjunction with DNA2 helicase/nuclease in 5'-flap extension during Okazaki fragment processing.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

1136231:CORT 0B01380
gene id: 1136231:CORT_0B01380
uniprot id: H8WZI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

1136231:CORT 0B10550
gene id: 1136231:CORT_0B10550
uniprot id: H8X237
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136231:CORT 0D06690
gene id: 1136231:CORT_0D06690
uniprot id: H8X5P5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D05120
gene id: 1136231:CORT_0D05120
uniprot id: H8X6A4
names: Similarity
messages: Belongs to the WD repeat LST8 family.

1136231:CORT 0A13280
gene id: 1136231:CORT_0A13280
uniprot id: H8WXN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

1136231:CORT 0B03850
gene id: 1136231:CORT_0B03850
uniprot id: H8X153
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0D05730
gene id: 1136231:CORT_0D05730
uniprot id: H8X5F5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A00570
gene id: 1136231:CORT_0A00570
uniprot id: H8WVH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

1136231:CORT 0B06360
gene id: 1136231:CORT_0B06360
uniprot id: H8X000
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Inhibits the enzyme activity of ATPase.
messages: Mitochondrion

1136231:CORT 0B02150
gene id: 1136231:CORT_0B02150
uniprot id: H8X0P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0A05090
gene id: 1136231:CORT_0A05090
uniprot id: H8WXV0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0A12930
gene id: 1136231:CORT_0A12930
uniprot id: H8WZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

1136231:CORT 0C00170
gene id: 1136231:CORT_0C00170
uniprot id: H8X3C3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1136231:CORT 0D06490
gene id: 1136231:CORT_0D06490
uniprot id: H8X5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

1136231:CORT 0D03540
gene id: 1136231:CORT_0D03540
uniprot id: H8X5A3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1136231:CORT 0A00380
gene id: 1136231:CORT_0A00380
uniprot id: H8WVF9
names: Similarity
messages: Belongs to the BolA/IbaG family.

1136231:CORT 0D01020
gene id: 1136231:CORT_0D01020
uniprot id: H8X4K8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A04010
gene id: 1136231:CORT_0A04010
uniprot id: H8WWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

1136231:CORT 0E03390
gene id: 1136231:CORT_0E03390
uniprot id: H8X6Z9
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0H01220
gene id: 1136231:CORT_0H01220
uniprot id: H8XAZ0
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1136231:CORT 0B02060
gene id: 1136231:CORT_0B02060
uniprot id: H8X0N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

1136231:CORT 0A12350
gene id: 1136231:CORT_0A12350
uniprot id: H8WYY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

1136231:CORT 0C02540
gene id: 1136231:CORT_0C02540
uniprot id: H8X2T2
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

1136231:CORT 0B02110
gene id: 1136231:CORT_0B02110
uniprot id: H8X0P0
names: Similarity
messages: Belongs to the SAP30 family.

1136231:CORT 0H00660
gene id: 1136231:CORT_0H00660
uniprot id: H8XBJ5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G02320
gene id: 1136231:CORT_0G02320
uniprot id: H8XAR2
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

1136231:CORT 0E01830
gene id: 1136231:CORT_0E01830
uniprot id: H8X7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1136231:CORT 0B03140
gene id: 1136231:CORT_0B03140
uniprot id: H8X0Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

1136231:CORT 0F00800
gene id: 1136231:CORT_0F00800
uniprot id: H8X910
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

1136231:CORT 0D03330
gene id: 1136231:CORT_0D03330
uniprot id: H8X583
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1136231:CORT 0E02740
gene id: 1136231:CORT_0E02740
uniprot id: H8X7S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIF1/spd1 family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0G03490
gene id: 1136231:CORT_0G03490
uniprot id: H8XA48
names: Function
names: Similarity
messages: Belongs to the NUP family.
messages: Nucleoside permease that transports adenosine and guanosine.

1136231:CORT 0A01180
gene id: 1136231:CORT_0A01180
uniprot id: H8WVN6
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anamorsin family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

1136231:CORT 0B01890
gene id: 1136231:CORT_0B01890
uniprot id: H8X0L8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

1136231:CORT 0E00770
gene id: 1136231:CORT_0E00770
uniprot id: H8X6Q5
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1136231:CORT 0D07480
gene id: 1136231:CORT_0D07480
uniprot id: H8X6H0
names: Similarity
messages: Belongs to the AAA ATPase family.

1136231:CORT 0A02390
gene id: 1136231:CORT_0A02390
uniprot id: H8WW06
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

1136231:CORT 0A03730
gene id: 1136231:CORT_0A03730
uniprot id: H8WWD7
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

1136231:CORT 0H02130
gene id: 1136231:CORT_0H02130
uniprot id: H8XB75
names: Similarity
messages: Belongs to the peptidase A22B family.

1136231:CORT 0A13430
gene id: 1136231:CORT_0A13430
uniprot id: H8WXQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.
messages: Nucleus

1136231:CORT 0H00320
gene id: 1136231:CORT_0H00320
uniprot id: H8XBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endopolyphosphatase PPN1 family.
messages: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0A06040
gene id: 1136231:CORT_0A06040
uniprot id: H8WY44
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

1136231:CORT 0G03190
gene id: 1136231:CORT_0G03190
uniprot id: H8XA19
names: Similarity
messages: Belongs to the MIP18 family.

1136231:CORT 0A11810
gene id: 1136231:CORT_0A11810
uniprot id: H8WYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC4 family.
messages: Mitochondrion intermembrane space

1136231:CORT 0A05540
gene id: 1136231:CORT_0A05540
uniprot id: H8WXZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0E06570
gene id: 1136231:CORT_0E06570
uniprot id: H8X7E4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H02600
gene id: 1136231:CORT_0H02600
uniprot id: H8XBC1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B02540
gene id: 1136231:CORT_0B02540
uniprot id: H8X0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1136231:CORT 0G02510
gene id: 1136231:CORT_0G02510
uniprot id: H8XAT1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0D04030
gene id: 1136231:CORT_0D04030
uniprot id: H8X5Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
messages: Mitochondrion inner membrane

1136231:CORT 0C03320
gene id: 1136231:CORT_0C03320
uniprot id: H8X3R9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B00610
gene id: 1136231:CORT_0B00610
uniprot id: H8WZB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0H02480
gene id: 1136231:CORT_0H02480
uniprot id: H8XBA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

1136231:CORT 0B04640
gene id: 1136231:CORT_0B04640
uniprot id: H8X1D2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

1136231:CORT 0B01640
gene id: 1136231:CORT_0B01640
uniprot id: H8X0J4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family.
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.

1136231:CORT 0A03790
gene id: 1136231:CORT_0A03790
uniprot id: H8WWE3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1136231:CORT 0B03610
gene id: 1136231:CORT_0B03610
uniprot id: H8X129
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

1136231:CORT 0B07170
gene id: 1136231:CORT_0B07170
uniprot id: H8X1L9
names: Similarity
messages: Belongs to the APC1 family.

1136231:CORT 0A12020
gene id: 1136231:CORT_0A12020
uniprot id: H8WYV5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

1136231:CORT 0F00740
gene id: 1136231:CORT_0F00740
uniprot id: H8X905
names: Similarity
messages: Belongs to the VPS25 family.

1136231:CORT 0D05440
gene id: 1136231:CORT_0D05440
uniprot id: H8X6D5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

1136231:CORT 0F02790
gene id: 1136231:CORT_0F02790
uniprot id: H8X8M8
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1136231:CORT 0F01030
gene id: 1136231:CORT_0F01030
uniprot id: H8X932
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

1136231:CORT 0B05110
gene id: 1136231:CORT_0B05110
uniprot id: H8WZM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

1136231:CORT 0D00230
gene id: 1136231:CORT_0D00230
uniprot id: H8X5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

1136231:CORT 0G04150
gene id: 1136231:CORT_0G04150
uniprot id: H8XAB5
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0E01650
gene id: 1136231:CORT_0E01650
uniprot id: H8X7G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1136231:CORT 0F00490
gene id: 1136231:CORT_0F00490
uniprot id: H8X8Y0
names: Subcellular Location Annotation
messages: Mitochondrion

1136231:CORT 0A03500
gene id: 1136231:CORT_0A03500
uniprot id: H8WWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

1136231:CORT 0A08500
gene id: 1136231:CORT_0A08500
uniprot id: H8WYB9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs.

1136231:CORT 0A01450
gene id: 1136231:CORT_0A01450
uniprot id: H8WVR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Membrane

1136231:CORT 0A05880
gene id: 1136231:CORT_0A05880
uniprot id: H8WY28
names: Similarity
messages: Belongs to the nucleoporin Nup133 family.

1136231:CORT 0D02480
gene id: 1136231:CORT_0D02480
uniprot id: H8X503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

1136231:CORT 0C03650
gene id: 1136231:CORT_0C03650
uniprot id: H8X3V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RGI1 family.
messages: Cell membrane
messages: Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
messages: Membrane

1136231:CORT 0B08910
gene id: 1136231:CORT_0B08910
uniprot id: H8X083
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1136231:CORT 0A08780
gene id: 1136231:CORT_0A08780
uniprot id: H8WYE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

1136231:CORT 0G03910
gene id: 1136231:CORT_0G03910
uniprot id: H8XA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

1136231:CORT 0B07330
gene id: 1136231:CORT_0B07330
uniprot id: H8X1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane
messages: Membrane

1136231:CORT 0D03800
gene id: 1136231:CORT_0D03800
uniprot id: H8X5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

1136231:CORT 0C04700
gene id: 1136231:CORT_0C04700
uniprot id: H8X2Y4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C02680
gene id: 1136231:CORT_0C02680
uniprot id: H8X2U6
names: Similarity
messages: Belongs to the TRM112 family.

1136231:CORT 0C05570
gene id: 1136231:CORT_0C05570
uniprot id: H8X371
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1136231:CORT 0B07430
gene id: 1136231:CORT_0B07430
uniprot id: H8X1P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
messages: Membrane
messages: Preautophagosomal structure membrane

1136231:CORT 0A11910
gene id: 1136231:CORT_0A11910
uniprot id: H8WYU4
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

1136231:CORT 0H00940
gene id: 1136231:CORT_0H00940
uniprot id: H8XAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1136231:CORT 0A11650
gene id: 1136231:CORT_0A11650
uniprot id: H8WYR8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1136231:CORT 0E01180
gene id: 1136231:CORT_0E01180
uniprot id: H8X6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

1136231:CORT 0A11310
gene id: 1136231:CORT_0A11310
uniprot id: H8WXL0
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

1136231:CORT 0G03000
gene id: 1136231:CORT_0G03000
uniprot id: H8XA01
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

1136231:CORT 0C05760
gene id: 1136231:CORT_0C05760
uniprot id: H8X390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

1136231:CORT 0B08040
gene id: 1136231:CORT_0B08040
uniprot id: H8X1V3
names: Similarity
messages: Belongs to the cyclin family.

1136231:CORT 0D01920
gene id: 1136231:CORT_0D01920
uniprot id: H8X4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0D02420
gene id: 1136231:CORT_0D02420
uniprot id: H8X4Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B03130
gene id: 1136231:CORT_0B03130
uniprot id: H8X0Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

1136231:CORT 0D01220
gene id: 1136231:CORT_0D01220
uniprot id: H8X4M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

1136231:CORT 0F01180
gene id: 1136231:CORT_0F01180
uniprot id: H8X947
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

1136231:CORT 0D02000
gene id: 1136231:CORT_0D02000
uniprot id: H8X4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0C03310
gene id: 1136231:CORT_0C03310
uniprot id: H8X3R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0E05160
gene id: 1136231:CORT_0E05160
uniprot id: H8X802
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

1136231:CORT 0D04780
gene id: 1136231:CORT_0D04780
uniprot id: H8X670
names: Similarity
messages: Belongs to the TFIIB family.

1136231:CORT 0E04050
gene id: 1136231:CORT_0E04050
uniprot id: H8X764
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

1136231:CORT 0C02810
gene id: 1136231:CORT_0C02810
uniprot id: H8X3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B09280
gene id: 1136231:CORT_0B09280
uniprot id: H8X0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: May associate with the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.

1136231:CORT 0B08820
gene id: 1136231:CORT_0B08820
uniprot id: H8X074
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1136231:CORT 0D05070
gene id: 1136231:CORT_0D05070
uniprot id: H8X699
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1136231:CORT 0F04360
gene id: 1136231:CORT_0F04360
uniprot id: H8X9J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

1136231:CORT 0G02240
gene id: 1136231:CORT_0G02240
uniprot id: H8XAQ4
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0C05030
gene id: 1136231:CORT_0C05030
uniprot id: H8X317
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

1136231:CORT 0G01830
gene id: 1136231:CORT_0G01830
uniprot id: H8XAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.

1136231:CORT 0D04400
gene id: 1136231:CORT_0D04400
uniprot id: H8X632
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1136231:CORT 0B06650
gene id: 1136231:CORT_0B06650
uniprot id: H8X1G8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

1136231:CORT 0D06190
gene id: 1136231:CORT_0D06190
uniprot id: H8X5J9
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

1136231:CORT 0A01420
gene id: 1136231:CORT_0A01420
uniprot id: H8WVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

1136231:CORT 0A10830
gene id: 1136231:CORT_0A10830
uniprot id: H8WXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR1 family.
messages: Membrane

1136231:CORT 0C02380
gene id: 1136231:CORT_0C02380
uniprot id: H8X2R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1136231:CORT 0B07990
gene id: 1136231:CORT_0B07990
uniprot id: H8X1U8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1136231:CORT 0C06560
gene id: 1136231:CORT_0C06560
uniprot id: H8X477
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0B04980
gene id: 1136231:CORT_0B04980
uniprot id: H8WZL1
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

1136231:CORT 0E03070
gene id: 1136231:CORT_0E03070
uniprot id: H8X7W0
names: Similarity
messages: Belongs to the PPP phosphatase family.

1136231:CORT 0B07160
gene id: 1136231:CORT_0B07160
uniprot id: H8X1L8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

1136231:CORT 0A00900
gene id: 1136231:CORT_0A00900
uniprot id: H8WVK8
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

1136231:CORT 0C03170
gene id: 1136231:CORT_0C03170
uniprot id: H8X3Q4
names: Similarity
messages: Belongs to the CBF/MAK21 family.

1136231:CORT 0B10430
gene id: 1136231:CORT_0B10430
uniprot id: H8X224
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

1136231:CORT 0D05560
gene id: 1136231:CORT_0D05560
uniprot id: H8X5D9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A07580
gene id: 1136231:CORT_0A07580
uniprot id: H8WX04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

1136231:CORT 0A11740
gene id: 1136231:CORT_0A11740
uniprot id: H8WYS7
names: Similarity
messages: Belongs to the SGT family.

1136231:CORT 0D02740
gene id: 1136231:CORT_0D02740
uniprot id: H8X526
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

1136231:CORT 0H01130
gene id: 1136231:CORT_0H01130
uniprot id: H8XAY1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

1136231:CORT 0E00400
gene id: 1136231:CORT_0E00400
uniprot id: H8X6L9
names: Similarity
messages: Belongs to the SAS10 family.

1136231:CORT 0D03710
gene id: 1136231:CORT_0D03710
uniprot id: H8X5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

1136231:CORT 0B06550
gene id: 1136231:CORT_0B06550
uniprot id: H8X019
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1136231:CORT 0D04260
gene id: 1136231:CORT_0D04260
uniprot id: H8X618
names: Similarity
messages: Belongs to the WrbA family.

1136231:CORT 0D06970
gene id: 1136231:CORT_0D06970
uniprot id: H8X5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1136231:CORT 0C04060
gene id: 1136231:CORT_0C04060
uniprot id: H8X3Z2
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1136231:CORT 0A02010
gene id: 1136231:CORT_0A02010
uniprot id: H8WVW8
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0D01580
gene id: 1136231:CORT_0D01580
uniprot id: H8X4R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1136231:CORT 0E01350
gene id: 1136231:CORT_0E01350
uniprot id: H8X6W2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1136231:CORT 0E01440
gene id: 1136231:CORT_0E01440
uniprot id: H8X7E8
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

1136231:CORT 0G04470
gene id: 1136231:CORT_0G04470
uniprot id: H8XAE7
names: Function
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.

1136231:CORT 0D00640
gene id: 1136231:CORT_0D00640
uniprot id: H8X4H0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1136231:CORT 0E02250
gene id: 1136231:CORT_0E02250
uniprot id: H8X7M7
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1136231:CORT 0B03120
gene id: 1136231:CORT_0B03120
uniprot id: H8X0Y4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A09020
gene id: 1136231:CORT_0A09020
uniprot id: H8WYH1
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

1136231:CORT 0D03840
gene id: 1136231:CORT_0D03840
uniprot id: H8X5D0
names: Similarity
messages: Belongs to the PP2C family.

1136231:CORT 0F04295
gene id: 1136231:CORT_0F04295
uniprot id: H8X9I8
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0E06530
gene id: 1136231:CORT_0E06530
uniprot id: H8X7E0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1136231:CORT 0B08380
gene id: 1136231:CORT_0B08380
uniprot id: H8X032
names: Similarity
messages: Belongs to the MAD2 family.

1136231:CORT 0D06920
gene id: 1136231:CORT_0D06920
uniprot id: H8X5R7
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

1136231:CORT 0A01010
gene id: 1136231:CORT_0A01010
uniprot id: H8WVL9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

1136231:CORT 0D05290
gene id: 1136231:CORT_0D05290
uniprot id: H8X6C0
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1136231:CORT 0F03160
gene id: 1136231:CORT_0F03160
uniprot id: H8X8R5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

1136231:CORT 0A10790
gene id: 1136231:CORT_0A10790
uniprot id: H8WXF8
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0B07960
gene id: 1136231:CORT_0B07960
uniprot id: H8X1U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1136231:CORT 0D07160
gene id: 1136231:CORT_0D07160
uniprot id: H8X5U1
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

1136231:CORT 0G03300
gene id: 1136231:CORT_0G03300
uniprot id: H8XA30
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1136231:CORT 0A06770
gene id: 1136231:CORT_0A06770
uniprot id: H8WWS2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B00530
gene id: 1136231:CORT_0B00530
uniprot id: H8WZA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1136231:CORT 0B08240
gene id: 1136231:CORT_0B08240
uniprot id: H8X1X3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0B05940
gene id: 1136231:CORT_0B05940
uniprot id: H8WZV8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1136231:CORT 0C03860
gene id: 1136231:CORT_0C03860
uniprot id: H8X3X2
names: Similarity
messages: Belongs to the MUB1/samB family.

1136231:CORT 0B06210
gene id: 1136231:CORT_0B06210
uniprot id: H8WZY5
names: Similarity
messages: Belongs to the CBF/MAK21 family.

1136231:CORT 0B11520
gene id: 1136231:CORT_0B11520
uniprot id: H8X2C9
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

1136231:CORT 0B09470
gene id: 1136231:CORT_0B09470
uniprot id: H8X0D9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1136231:CORT 0H02390
gene id: 1136231:CORT_0H02390
uniprot id: H8XBA0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1136231:CORT 0D01740
gene id: 1136231:CORT_0D01740
uniprot id: H8X4T0
names: Similarity
messages: Belongs to the MAD1 family.

1136231:CORT 0C05890
gene id: 1136231:CORT_0C05890
uniprot id: H8X3A2
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0F01240
gene id: 1136231:CORT_0F01240
uniprot id: H8X953
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0G03870
gene id: 1136231:CORT_0G03870
uniprot id: H8XA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0A09080
gene id: 1136231:CORT_0A09080
uniprot id: H8WYH7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1136231:CORT 0D02930
gene id: 1136231:CORT_0D02930
uniprot id: H8X545
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0G04110
gene id: 1136231:CORT_0G04110
uniprot id: H8XAB1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136231:CORT 0A12920
gene id: 1136231:CORT_0A12920
uniprot id: H8WZ43
names: Subcellular Location Annotation
messages: Peroxisome membrane

1136231:CORT 0F00750
gene id: 1136231:CORT_0F00750
uniprot id: H8X906
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

1136231:CORT 0B07190
gene id: 1136231:CORT_0B07190
uniprot id: H8X1M1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

1136231:CORT 0D04290
gene id: 1136231:CORT_0D04290
uniprot id: H8X621
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1136231:CORT 0D01310
gene id: 1136231:CORT_0D01310
uniprot id: H8X4N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

1136231:CORT 0G00310
gene id: 1136231:CORT_0G00310
uniprot id: H8X9Q5
names: Similarity
messages: Belongs to the Rab GDI family.

1136231:CORT 0E03300
gene id: 1136231:CORT_0E03300
uniprot id: H8X6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B09580
gene id: 1136231:CORT_0B09580
uniprot id: H8X0F0
names: Subcellular Location Annotation
messages: Vacuole

1136231:CORT 0D07350
gene id: 1136231:CORT_0D07350
uniprot id: H8X6F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

1136231:CORT 0C04740
gene id: 1136231:CORT_0C04740
uniprot id: H8X2Y8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1136231:CORT 0A12740
gene id: 1136231:CORT_0A12740
uniprot id: H8WZ26
names: Similarity
messages: Belongs to the peptidase M24B family.

1136231:CORT 0D06450
gene id: 1136231:CORT_0D06450
uniprot id: H8X5M3
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0F04660
gene id: 1136231:CORT_0F04660
uniprot id: H8X9M5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A08140
gene id: 1136231:CORT_0A08140
uniprot id: H8WY84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: kinetochore
messages: spindle

1136231:CORT 0F00390
gene id: 1136231:CORT_0F00390
uniprot id: H8X8X0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G00740
gene id: 1136231:CORT_0G00740
uniprot id: H8X9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation.
messages: Mitochondrion inner membrane

1136231:CORT 0H02020
gene id: 1136231:CORT_0H02020
uniprot id: H8XB66
names: Similarity
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.

1136231:CORT 0D03130
gene id: 1136231:CORT_0D03130
uniprot id: H8X564
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

1136231:CORT 0C00290
gene id: 1136231:CORT_0C00290
uniprot id: H8X3D5
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1136231:CORT 0H01910
gene id: 1136231:CORT_0H01910
uniprot id: H8XB55
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

1136231:CORT 0D07290
gene id: 1136231:CORT_0D07290
uniprot id: H8X6F1
names: Similarity
messages: Belongs to the PET191 family.

1136231:CORT 0E06510
gene id: 1136231:CORT_0E06510
uniprot id: H8X7D8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1136231:CORT 0G01930
gene id: 1136231:CORT_0G01930
uniprot id: H8XAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD4 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1136231:CORT 0C03020
gene id: 1136231:CORT_0C03020
uniprot id: H8X3P0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0B08100
gene id: 1136231:CORT_0B08100
uniprot id: H8X1V9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1136231:CORT 0D07040
gene id: 1136231:CORT_0D07040
uniprot id: H8X5S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

1136231:CORT 0H01080
gene id: 1136231:CORT_0H01080
uniprot id: H8XAX6
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1136231:CORT 0A02000
gene id: 1136231:CORT_0A02000
uniprot id: H8WVW7
names: Similarity
messages: Belongs to the peptidase C48 family.

1136231:CORT 0A07560
gene id: 1136231:CORT_0A07560
uniprot id: H8WX02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.

1136231:CORT 0E04280
gene id: 1136231:CORT_0E04280
uniprot id: H8X786
names: Similarity
messages: Belongs to the SEC3 family.

1136231:CORT 0B05410
gene id: 1136231:CORT_0B05410
uniprot id: H8WZQ4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

1136231:CORT 0A06430
gene id: 1136231:CORT_0A06430
uniprot id: H8WWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1136231:CORT 0E00750
gene id: 1136231:CORT_0E00750
uniprot id: H8X6Q3
names: Similarity
messages: Belongs to the HGH1 family.

1136231:CORT 0A04890
gene id: 1136231:CORT_0A04890
uniprot id: H8WXT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAM1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1136231:CORT 0A03860
gene id: 1136231:CORT_0A03860
uniprot id: H8WWF0
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

1136231:CORT 0B01510
gene id: 1136231:CORT_0B01510
uniprot id: H8WZK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

1136231:CORT 0A07760
gene id: 1136231:CORT_0A07760
uniprot id: H8WX22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C1D family.
messages: Nucleus
messages: Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.

1136231:CORT 0B07640
gene id: 1136231:CORT_0B07640
uniprot id: H8X1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

1136231:CORT 0C03770
gene id: 1136231:CORT_0C03770
uniprot id: H8X3W4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G00820
gene id: 1136231:CORT_0G00820
uniprot id: H8X9V3
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

1136231:CORT 0H02560
gene id: 1136231:CORT_0H02560
uniprot id: H8XBB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE3 family.
messages: Endoplasmic reticulum membrane
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.

1136231:CORT 0A00840
gene id: 1136231:CORT_0A00840
uniprot id: H8WVK2
names: Similarity
messages: Belongs to the NEMF family.

1136231:CORT 0A13230
gene id: 1136231:CORT_0A13230
uniprot id: H8WXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

1136231:CORT 0G03060
gene id: 1136231:CORT_0G03060
uniprot id: H8XA07
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B00970
gene id: 1136231:CORT_0B00970
uniprot id: H8WZE9
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Monomer.

1136231:CORT 0A02560
gene id: 1136231:CORT_0A02560
uniprot id: H8WW23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0H00330
gene id: 1136231:CORT_0H00330
uniprot id: H8XBG3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

1136231:CORT 0G00980
gene id: 1136231:CORT_0G00980
uniprot id: H8X9W9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136231:CORT 0E04850
gene id: 1136231:CORT_0E04850
uniprot id: H8X7X0
names: Similarity
messages: Belongs to the importin alpha family.

1136231:CORT 0A05860
gene id: 1136231:CORT_0A05860
uniprot id: H8WY26
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1136231:CORT 0H02450
gene id: 1136231:CORT_0H02450
uniprot id: H8XBA6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0G01570
gene id: 1136231:CORT_0G01570
uniprot id: H8XAJ4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

1136231:CORT 0A04020
gene id: 1136231:CORT_0A04020
uniprot id: H8WWG6
names: Similarity
messages: Belongs to the WD repeat PWP2 family.

1136231:CORT 0G03580
gene id: 1136231:CORT_0G03580
uniprot id: H8XA57
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1136231:CORT 0C02440
gene id: 1136231:CORT_0C02440
uniprot id: H8X2S2
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0A04650
gene id: 1136231:CORT_0A04650
uniprot id: H8WWM9
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

1136231:CORT 0A01740
gene id: 1136231:CORT_0A01740
uniprot id: H8WVU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0B04920
gene id: 1136231:CORT_0B04920
uniprot id: H8X1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

1136231:CORT 0D00730
gene id: 1136231:CORT_0D00730
uniprot id: H8X4H9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1136231:CORT 0D01980
gene id: 1136231:CORT_0D01980
uniprot id: H8X4V4
names: Similarity
messages: Belongs to the RICTOR family.

1136231:CORT 0A01560
gene id: 1136231:CORT_0A01560
uniprot id: H8WVS4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A12700
gene id: 1136231:CORT_0A12700
uniprot id: H8WZ22
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1136231:CORT 0G00240
gene id: 1136231:CORT_0G00240
uniprot id: H8X9P8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E03650
gene id: 1136231:CORT_0E03650
uniprot id: H8X725
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C04770
gene id: 1136231:CORT_0C04770
uniprot id: H8X2Z1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THI4 family.
messages: Binds 1 Fe cation per subunit.
messages: Cytoplasm
messages: During the catalytic reaction, a sulfide is transferred from Cys-211 to a reaction intermediate, generating a dehydroalanine residue.
messages: Homooctamer.
messages: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
messages: Nucleus

1136231:CORT 0C04830
gene id: 1136231:CORT_0C04830
uniprot id: H8X2Z7
names: Similarity
messages: Belongs to the peptidase C14B family.

1136231:CORT 0B03580
gene id: 1136231:CORT_0B03580
uniprot id: H8X126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

1136231:CORT 0D03400
gene id: 1136231:CORT_0D03400
uniprot id: H8X589
names: Similarity
messages: Belongs to the FGGY kinase family.

1136231:CORT 0E01120
gene id: 1136231:CORT_0E01120
uniprot id: H8X6U0
names: Similarity
messages: Belongs to the ELP6 family.

1136231:CORT 0A02950
gene id: 1136231:CORT_0A02950
uniprot id: H8WW60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

1136231:CORT 0B07560
gene id: 1136231:CORT_0B07560
uniprot id: H8X1Q7
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

1136231:CORT 0G02360
gene id: 1136231:CORT_0G02360
uniprot id: H8XAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

1136231:CORT 0B04080
gene id: 1136231:CORT_0B04080
uniprot id: H8X175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0D06210
gene id: 1136231:CORT_0D06210
uniprot id: H8X5K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

1136231:CORT 0C02740
gene id: 1136231:CORT_0C02740
uniprot id: H8X3L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYR1/IFF family.
messages: GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence.
messages: Membrane
messages: cell wall

1136231:CORT 0B00260
gene id: 1136231:CORT_0B00260
uniprot id: H8WZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

1136231:CORT 0H01640
gene id: 1136231:CORT_0H01640
uniprot id: H8XB29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1136231:CORT 0C00230
gene id: 1136231:CORT_0C00230
uniprot id: H8X3C9
names: Similarity
messages: Belongs to the lysophospholipase family.

1136231:CORT 0E06200
gene id: 1136231:CORT_0E06200
uniprot id: H8X8A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

1136231:CORT 0B01770
gene id: 1136231:CORT_0B01770
uniprot id: H8X0K6
names: Similarity
messages: Belongs to the FYV7 family.

1136231:CORT 0B06420
gene id: 1136231:CORT_0B06420
uniprot id: H8X006
names: Similarity
messages: Belongs to the SKP1 family.

1136231:CORT 0C00380
gene id: 1136231:CORT_0C00380
uniprot id: H8X3E4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A05530
gene id: 1136231:CORT_0A05530
uniprot id: H8WXZ3
names: Similarity
messages: Belongs to the CWC21 family.

1136231:CORT 0B07460
gene id: 1136231:CORT_0B07460
uniprot id: H8X1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1136231:CORT 0H02760
gene id: 1136231:CORT_0H02760
uniprot id: H8XBD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion
messages: nucleolus

1136231:CORT 0B01880
gene id: 1136231:CORT_0B01880
uniprot id: H8X0L7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

1136231:CORT 0A03740
gene id: 1136231:CORT_0A03740
uniprot id: H8WWD8
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1136231:CORT 0F03350
gene id: 1136231:CORT_0F03350
uniprot id: H8X8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD18 family.
messages: E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
messages: Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.
messages: Nucleus

1136231:CORT 0B05490
gene id: 1136231:CORT_0B05490
uniprot id: H8WZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0B02510
gene id: 1136231:CORT_0B02510
uniprot id: H8X0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Membrane

1136231:CORT 0A00470
gene id: 1136231:CORT_0A00470
uniprot id: H8WVG8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B09200
gene id: 1136231:CORT_0B09200
uniprot id: H8X0B2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus

1136231:CORT 0H02590
gene id: 1136231:CORT_0H02590
uniprot id: H8XBC0
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

1136231:CORT 0B04800
gene id: 1136231:CORT_0B04800
uniprot id: H8X1E8
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

1136231:CORT 0F02500
gene id: 1136231:CORT_0F02500
uniprot id: H8X8K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1136231:CORT 0B05070
gene id: 1136231:CORT_0B05070
uniprot id: H8WZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0A09800
gene id: 1136231:CORT_0A09800
uniprot id: H8WX60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

1136231:CORT 0F02150
gene id: 1136231:CORT_0F02150
uniprot id: H8X8G5
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1136231:CORT 0E04580
gene id: 1136231:CORT_0E04580
uniprot id: H8X7B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

1136231:CORT 0D05720
gene id: 1136231:CORT_0D05720
uniprot id: H8X5F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0A05230
gene id: 1136231:CORT_0A05230
uniprot id: H8WXW4
names: Similarity
messages: Belongs to the AFG1 ATPase family.

1136231:CORT 0D01600
gene id: 1136231:CORT_0D01600
uniprot id: H8X4R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1136231:CORT 0A11990
gene id: 1136231:CORT_0A11990
uniprot id: H8WYV2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1136231:CORT 0C03090
gene id: 1136231:CORT_0C03090
uniprot id: H8X3P7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

1136231:CORT 0E04550
gene id: 1136231:CORT_0E04550
uniprot id: H8X7B2
names: Similarity
messages: Belongs to the MGMT family.

1136231:CORT 0B11340
gene id: 1136231:CORT_0B11340
uniprot id: H8X2B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LOT5 family.
messages: Nucleus

1136231:CORT 0E00120
gene id: 1136231:CORT_0E00120
uniprot id: H8X6J2
names: Similarity
messages: Belongs to the PP2C family.

1136231:CORT 0C06650
gene id: 1136231:CORT_0C06650
uniprot id: H8X485
names: Similarity
messages: Belongs to the peptidase M20A family.

1136231:CORT 0A12850
gene id: 1136231:CORT_0A12850
uniprot id: H8WZ36
names: Similarity
messages: Belongs to the cytidylyltransferase family.

1136231:CORT 0H01800
gene id: 1136231:CORT_0H01800
uniprot id: H8XB44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

1136231:CORT 0G03660
gene id: 1136231:CORT_0G03660
uniprot id: H8XA65
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1136231:CORT 0D07380
gene id: 1136231:CORT_0D07380
uniprot id: H8X6G0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D00660
gene id: 1136231:CORT_0D00660
uniprot id: H8X4H2
names: Similarity
messages: Belongs to the AHA1 family.

1136231:CORT 0F00680
gene id: 1136231:CORT_0F00680
uniprot id: H8X8Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1136231:CORT 0A06080
gene id: 1136231:CORT_0A06080
uniprot id: H8WY48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0A11420
gene id: 1136231:CORT_0A11420
uniprot id: H8WYP5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C01540
gene id: 1136231:CORT_0C01540
uniprot id: H8X2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

1136231:CORT 0B01500
gene id: 1136231:CORT_0B01500
uniprot id: H8WZK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum membrane
messages: Functions as a zinc transporter.
messages: Membrane

1136231:CORT 0G02440
gene id: 1136231:CORT_0G02440
uniprot id: H8XAS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136231:CORT 0G02570
gene id: 1136231:CORT_0G02570
uniprot id: H8XAT7
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1136231:CORT 0A09330
gene id: 1136231:CORT_0A09330
uniprot id: H8WYK2
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0C00770
gene id: 1136231:CORT_0C00770
uniprot id: H8X3I1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A03670
gene id: 1136231:CORT_0A03670
uniprot id: H8WWD1
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0G04020
gene id: 1136231:CORT_0G04020
uniprot id: H8XAA2
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0G01350
gene id: 1136231:CORT_0G01350
uniprot id: H8XAH3
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

1136231:CORT 0D06440
gene id: 1136231:CORT_0D06440
uniprot id: H8X5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

1136231:CORT 0E01050
gene id: 1136231:CORT_0E01050
uniprot id: H8X6T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1136231:CORT 0B02620
gene id: 1136231:CORT_0B02620
uniprot id: H8X0T8
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1136231:CORT 0B11080
gene id: 1136231:CORT_0B11080
uniprot id: H8X285
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

1136231:CORT 0A04920
gene id: 1136231:CORT_0A04920
uniprot id: H8WXT3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0D00360
gene id: 1136231:CORT_0D00360
uniprot id: H8X5X1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136231:CORT 0E02810
gene id: 1136231:CORT_0E02810
uniprot id: H8X7T2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.
messages: Membrane
messages: Peroxisome membrane

1136231:CORT 0A03870
gene id: 1136231:CORT_0A03870
uniprot id: H8WWF1
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

1136231:CORT 0B02360
gene id: 1136231:CORT_0B02360
uniprot id: H8X0R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1136231:CORT 0C06690
gene id: 1136231:CORT_0C06690
uniprot id: H8X489
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

1136231:CORT 0E00100
gene id: 1136231:CORT_0E00100
uniprot id: H8X6J0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1136231:CORT 0B01320
gene id: 1136231:CORT_0B01320
uniprot id: H8WZI3
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

1136231:CORT 0C03160
gene id: 1136231:CORT_0C03160
uniprot id: H8X3Q3
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0B02570
gene id: 1136231:CORT_0B02570
uniprot id: H8X0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B01150
gene id: 1136231:CORT_0B01150
uniprot id: H8WZG7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

1136231:CORT 0E03330
gene id: 1136231:CORT_0E03330
uniprot id: H8X6Z3
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1136231:CORT 0A04370
gene id: 1136231:CORT_0A04370
uniprot id: H8WWK1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E04790
gene id: 1136231:CORT_0E04790
uniprot id: H8X7W5
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1136231:CORT 0C02990
gene id: 1136231:CORT_0C02990
uniprot id: H8X3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

1136231:CORT 0F02060
gene id: 1136231:CORT_0F02060
uniprot id: H8X8F6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F02440
gene id: 1136231:CORT_0F02440
uniprot id: H8X8J4
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1136231:CORT 0D01910
gene id: 1136231:CORT_0D01910
uniprot id: H8X4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

1136231:CORT 0A07380
gene id: 1136231:CORT_0A07380
uniprot id: H8WWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1136231:CORT 0A00290
gene id: 1136231:CORT_0A00290
uniprot id: H8WVF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1136231:CORT 0B03330
gene id: 1136231:CORT_0B03330
uniprot id: H8X103
names: Similarity
messages: Belongs to the END3 family.

1136231:CORT 0C06170
gene id: 1136231:CORT_0C06170
uniprot id: H8X438
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

1136231:CORT 0B08550
gene id: 1136231:CORT_0B08550
uniprot id: H8X047
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B09160
gene id: 1136231:CORT_0B09160
uniprot id: H8X0A8
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

1136231:CORT 0A04900
gene id: 1136231:CORT_0A04900
uniprot id: H8WXT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Membrane
messages: Mitochondrion outer membrane

1136231:CORT 0G01670
gene id: 1136231:CORT_0G01670
uniprot id: H8XAK4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1136231:CORT 0C06820
gene id: 1136231:CORT_0C06820
uniprot id: H8X4A2
names: Similarity
messages: Belongs to the peptidase C19 family.

1136231:CORT 0E06110
gene id: 1136231:CORT_0E06110
uniprot id: H8X894
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.

1136231:CORT 0B05640
gene id: 1136231:CORT_0B05640
uniprot id: H8WZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX9 family.
messages: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3 snoRNA.
messages: Involved in ribosome biogenesis. Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1). May be involved in the movements of the replication forks.
messages: nucleolus

1136231:CORT 0B03100
gene id: 1136231:CORT_0B03100
uniprot id: H8X0Y2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0D03460
gene id: 1136231:CORT_0D03460
uniprot id: H8X595
names: Similarity
messages: Belongs to the V-ATPase H subunit family.

1136231:CORT 0B00720
gene id: 1136231:CORT_0B00720
uniprot id: H8WZC5
names: Similarity
messages: Belongs to the PHAF1 family.

1136231:CORT 0E01660
gene id: 1136231:CORT_0E01660
uniprot id: H8X7G9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

1136231:CORT 0A07810
gene id: 1136231:CORT_0A07810
uniprot id: H8WX27
names: Similarity
messages: Belongs to the SurE nucleotidase family.

1136231:CORT 0B02140
gene id: 1136231:CORT_0B02140
uniprot id: H8X0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

1136231:CORT 0B06270
gene id: 1136231:CORT_0B06270
uniprot id: H8WZZ1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136231:CORT 0C04110
gene id: 1136231:CORT_0C04110
uniprot id: H8X3Z6
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0A01670
gene id: 1136231:CORT_0A01670
uniprot id: H8WVT5
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

1136231:CORT 0H00240
gene id: 1136231:CORT_0H00240
uniprot id: H8XBF4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0C06550
gene id: 1136231:CORT_0C06550
uniprot id: H8X476
names: Function
names: Subcellular Location Annotation
messages: Chromosome
messages: Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression.
messages: Nucleus

1136231:CORT 0B07230
gene id: 1136231:CORT_0B07230
uniprot id: H8X1M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Mitochondrion inner membrane

1136231:CORT 0B08630
gene id: 1136231:CORT_0B08630
uniprot id: H8X055
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Vacuole membrane

1136231:CORT 0A12550
gene id: 1136231:CORT_0A12550
uniprot id: H8WZ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

1136231:CORT 0D02820
gene id: 1136231:CORT_0D02820
uniprot id: H8X534
names: Function
names: Similarity
messages: Belongs to the CWC15 family.
messages: Involved in pre-mRNA splicing.

1136231:CORT 0H01950
gene id: 1136231:CORT_0H01950
uniprot id: H8XB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1136231:CORT 0F00700
gene id: 1136231:CORT_0F00700
uniprot id: H8X901
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

1136231:CORT 0B05790
gene id: 1136231:CORT_0B05790
uniprot id: H8WZU3
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

1136231:CORT 0G02720
gene id: 1136231:CORT_0G02720
uniprot id: H8XAV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

1136231:CORT 0A11250
gene id: 1136231:CORT_0A11250
uniprot id: H8WXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

1136231:CORT 0F00980
gene id: 1136231:CORT_0F00980
uniprot id: H8X928
names: Similarity
messages: Belongs to the phospholipid scramblase family.

1136231:CORT 0B07340
gene id: 1136231:CORT_0B07340
uniprot id: H8X1N6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: cytosol

1136231:CORT 0A12160
gene id: 1136231:CORT_0A12160
uniprot id: H8WYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0F00340
gene id: 1136231:CORT_0F00340
uniprot id: H8X8W5
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

1136231:CORT 0D01520
gene id: 1136231:CORT_0D01520
uniprot id: H8X4Q8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1136231:CORT 0C07160
gene id: 1136231:CORT_0C07160
uniprot id: H8X4D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC2 family.
messages: Nucleus

1136231:CORT 0C00980
gene id: 1136231:CORT_0C00980
uniprot id: H8X3K2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B10630
gene id: 1136231:CORT_0B10630
uniprot id: H8X243
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1136231:CORT 0E03580
gene id: 1136231:CORT_0E03580
uniprot id: H8X718
names: Similarity
messages: Belongs to the OSBP family.

1136231:CORT 0G02530
gene id: 1136231:CORT_0G02530
uniprot id: H8XAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0H01020
gene id: 1136231:CORT_0H01020
uniprot id: H8XAX0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136231:CORT 0A12770
gene id: 1136231:CORT_0A12770
uniprot id: H8WZ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

1136231:CORT 0B04100
gene id: 1136231:CORT_0B04100
uniprot id: H8X177
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1136231:CORT 0C01100
gene id: 1136231:CORT_0C01100
uniprot id: H8X2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

1136231:CORT 0A08610
gene id: 1136231:CORT_0A08610
uniprot id: H8WYD0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A08830
gene id: 1136231:CORT_0A08830
uniprot id: H8WYF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

1136231:CORT 0E01040
gene id: 1136231:CORT_0E01040
uniprot id: H8X6T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

1136231:CORT 0B03420
gene id: 1136231:CORT_0B03420
uniprot id: H8X110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

1136231:CORT 0B08280
gene id: 1136231:CORT_0B08280
uniprot id: H8X1X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
messages: Membrane

1136231:CORT 0A09770
gene id: 1136231:CORT_0A09770
uniprot id: H8WX57
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1136231:CORT 0B07650
gene id: 1136231:CORT_0B07650
uniprot id: H8X1R6
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

1136231:CORT 0G02040
gene id: 1136231:CORT_0G02040
uniprot id: H8XAN5
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0A00850
gene id: 1136231:CORT_0A00850
uniprot id: H8WVK3
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

1136231:CORT 0B05150
gene id: 1136231:CORT_0B05150
uniprot id: H8WZM8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1136231:CORT 0E05060
gene id: 1136231:CORT_0E05060
uniprot id: H8X7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

1136231:CORT 0A11560
gene id: 1136231:CORT_0A11560
uniprot id: H8WYQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0A06230
gene id: 1136231:CORT_0A06230
uniprot id: H8WY63
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1136231:CORT 0G00260
gene id: 1136231:CORT_0G00260
uniprot id: H8X9Q0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B01420
gene id: 1136231:CORT_0B01420
uniprot id: H8WZJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

1136231:CORT 0E06430
gene id: 1136231:CORT_0E06430
uniprot id: H8X8C5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1136231:CORT 0A10490
gene id: 1136231:CORT_0A10490
uniprot id: H8WXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DPH4 family.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.

1136231:CORT 0A05460
gene id: 1136231:CORT_0A05460
uniprot id: H8WXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

1136231:CORT 0G01620
gene id: 1136231:CORT_0G01620
uniprot id: H8XAJ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0C07000
gene id: 1136231:CORT_0C07000
uniprot id: H8X4B9
names: Subunit
messages: Monomer.

1136231:CORT 0B09240
gene id: 1136231:CORT_0B09240
uniprot id: H8X0B6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F01440
gene id: 1136231:CORT_0F01440
uniprot id: H8X972
names: Similarity
messages: Belongs to the aldo/keto reductase family.

1136231:CORT 0G03040
gene id: 1136231:CORT_0G03040
uniprot id: H8XA05
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A08730
gene id: 1136231:CORT_0A08730
uniprot id: H8WYE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

1136231:CORT 0A07530
gene id: 1136231:CORT_0A07530
uniprot id: H8WWZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1136231:CORT 0B08570
gene id: 1136231:CORT_0B08570
uniprot id: H8X049
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

1136231:CORT 0A06300
gene id: 1136231:CORT_0A06300
uniprot id: H8WY69
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

1136231:CORT 0E03750
gene id: 1136231:CORT_0E03750
uniprot id: H8X735
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

1136231:CORT 0B06830
gene id: 1136231:CORT_0B06830
uniprot id: H8X1I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1136231:CORT 0A11390
gene id: 1136231:CORT_0A11390
uniprot id: H8WYP2
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0A01280
gene id: 1136231:CORT_0A01280
uniprot id: H8WVP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

1136231:CORT 0D01630
gene id: 1136231:CORT_0D01630
uniprot id: H8X4R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1136231:CORT 0C04800
gene id: 1136231:CORT_0C04800
uniprot id: H8X2Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: nucleolus

1136231:CORT 0A04710
gene id: 1136231:CORT_0A04710
uniprot id: H8WXR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 15 family.
messages: Nucleus

1136231:CORT 0B09410
gene id: 1136231:CORT_0B09410
uniprot id: H8X0D3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D04310
gene id: 1136231:CORT_0D04310
uniprot id: H8X623
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

1136231:CORT 0C00180
gene id: 1136231:CORT_0C00180
uniprot id: H8X3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1136231:CORT 0A11700
gene id: 1136231:CORT_0A11700
uniprot id: H8WYS3
names: Similarity
messages: Belongs to the YOS1 family.

1136231:CORT 0E05380
gene id: 1136231:CORT_0E05380
uniprot id: H8X824
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1136231:CORT 0A12000
gene id: 1136231:CORT_0A12000
uniprot id: H8WYV3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM34 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

1136231:CORT 0E02330
gene id: 1136231:CORT_0E02330
uniprot id: H8X7N5
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

1136231:CORT 0H01720
gene id: 1136231:CORT_0H01720
uniprot id: H8XB36
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D06200
gene id: 1136231:CORT_0D06200
uniprot id: H8X5K0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B05610
gene id: 1136231:CORT_0B05610
uniprot id: H8WZS4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

1136231:CORT 0B04940
gene id: 1136231:CORT_0B04940
uniprot id: H8X1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPL4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway.
messages: Membrane
messages: Nucleus membrane
messages: perinuclear region

1136231:CORT 0A03050
gene id: 1136231:CORT_0A03050
uniprot id: H8WW70
names: Similarity
messages: Belongs to the PP2C family.

1136231:CORT 0C00390
gene id: 1136231:CORT_0C00390
uniprot id: H8X3E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

1136231:CORT 0D05630
gene id: 1136231:CORT_0D05630
uniprot id: H8X5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPR3 family.
messages: Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.
messages: Vacuole membrane

1136231:CORT 0D03530
gene id: 1136231:CORT_0D03530
uniprot id: H8X5A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

1136231:CORT 0A03650
gene id: 1136231:CORT_0A03650
uniprot id: H8WWC9
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

1136231:CORT 0A02160
gene id: 1136231:CORT_0A02160
uniprot id: H8WVY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0A07940
gene id: 1136231:CORT_0A07940
uniprot id: H8WX40
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

1136231:CORT 0B03190
gene id: 1136231:CORT_0B03190
uniprot id: H8X0Z0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B01520
gene id: 1136231:CORT_0B01520
uniprot id: H8WZK3
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1136231:CORT 0B07360
gene id: 1136231:CORT_0B07360
uniprot id: H8X1N7
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0G02160
gene id: 1136231:CORT_0G02160
uniprot id: H8XAP7
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0H02240
gene id: 1136231:CORT_0H02240
uniprot id: H8XB85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

1136231:CORT 0C03740
gene id: 1136231:CORT_0C03740
uniprot id: H8X3W1
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1136231:CORT 0B07630
gene id: 1136231:CORT_0B07630
uniprot id: H8X1R4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A10240
gene id: 1136231:CORT_0A10240
uniprot id: H8WXA4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D02430
gene id: 1136231:CORT_0D02430
uniprot id: H8X4Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

1136231:CORT 0C02080
gene id: 1136231:CORT_0C02080
uniprot id: H8X2N7
names: Similarity
messages: Belongs to the PPC synthetase family.

1136231:CORT 0D04920
gene id: 1136231:CORT_0D04920
uniprot id: H8X684
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. CPD1 family.
messages: Golgi apparatus
messages: Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.

1136231:CORT 0D01470
gene id: 1136231:CORT_0D01470
uniprot id: H8X4Q3
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

1136231:CORT 0B03730
gene id: 1136231:CORT_0B03730
uniprot id: H8X141
names: Similarity
messages: Belongs to the peptidase M14 family.

1136231:CORT 0F01690
gene id: 1136231:CORT_0F01690
uniprot id: H8X997
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0A10060
gene id: 1136231:CORT_0A10060
uniprot id: H8WX86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0B07700
gene id: 1136231:CORT_0B07700
uniprot id: H8X1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

1136231:CORT 0E01790
gene id: 1136231:CORT_0E01790
uniprot id: H8X7I2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B11120
gene id: 1136231:CORT_0B11120
uniprot id: H8X289
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B03090
gene id: 1136231:CORT_0B03090
uniprot id: H8X0Y1
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1136231:CORT 0B06860
gene id: 1136231:CORT_0B06860
uniprot id: H8X1I9
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0B08620
gene id: 1136231:CORT_0B08620
uniprot id: H8X054
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

1136231:CORT 0A09440
gene id: 1136231:CORT_0A09440
uniprot id: H8WYL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

1136231:CORT 0C05900
gene id: 1136231:CORT_0C05900
uniprot id: H8X3A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1136231:CORT 0B09110
gene id: 1136231:CORT_0B09110
uniprot id: H8X0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

1136231:CORT 0A07830
gene id: 1136231:CORT_0A07830
uniprot id: H8WX29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

1136231:CORT 0A03560
gene id: 1136231:CORT_0A03560
uniprot id: H8WWC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

1136231:CORT 0A00700
gene id: 1136231:CORT_0A00700
uniprot id: H8WVI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
messages: Nucleus

1136231:CORT 0A01430
gene id: 1136231:CORT_0A01430
uniprot id: H8WVR2
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0B09600
gene id: 1136231:CORT_0B09600
uniprot id: H8X0F2
names: Function
names: Similarity
messages: Belongs to the BLOC1S4 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.

1136231:CORT 0C03470
gene id: 1136231:CORT_0C03470
uniprot id: H8X3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

1136231:CORT 0F03340
gene id: 1136231:CORT_0F03340
uniprot id: H8X8T3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B11150
gene id: 1136231:CORT_0B11150
uniprot id: H8X292
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

1136231:CORT 0H02280
gene id: 1136231:CORT_0H02280
uniprot id: H8XB89
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1136231:CORT 0B10530
gene id: 1136231:CORT_0B10530
uniprot id: H8X234
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0B00280
gene id: 1136231:CORT_0B00280
uniprot id: H8WZ83
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0B07660
gene id: 1136231:CORT_0B07660
uniprot id: H8X1R7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

1136231:CORT 0B04520
gene id: 1136231:CORT_0B04520
uniprot id: H8X1C0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D03260
gene id: 1136231:CORT_0D03260
uniprot id: H8X576
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

1136231:CORT 0D05760
gene id: 1136231:CORT_0D05760
uniprot id: H8X5F8
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

1136231:CORT 0C05820
gene id: 1136231:CORT_0C05820
uniprot id: H8X395
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0B08200
gene id: 1136231:CORT_0B08200
uniprot id: H8X1W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

1136231:CORT 0D03310
gene id: 1136231:CORT_0D03310
uniprot id: H8X1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1136231:CORT 0B03980
gene id: 1136231:CORT_0B03980
uniprot id: H8X166
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

1136231:CORT 0B11060
gene id: 1136231:CORT_0B11060
uniprot id: H8X283
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Nuclear serine protease which mediates apoptosis.
messages: Nucleus

1136231:CORT 0A07500
gene id: 1136231:CORT_0A07500
uniprot id: H8WWZ6
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

1136231:CORT 0F02240
gene id: 1136231:CORT_0F02240
uniprot id: H8X8H4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

1136231:CORT 0H02620
gene id: 1136231:CORT_0H02620
uniprot id: H8XBC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 chromatin remodeling complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.
messages: Nucleus

1136231:CORT 0D04690
gene id: 1136231:CORT_0D04690
uniprot id: H8X661
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 5 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0B02600
gene id: 1136231:CORT_0B02600
uniprot id: H8X0T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GEP5 family.
messages: Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins.
messages: Mitochondrion

1136231:CORT 0B04070
gene id: 1136231:CORT_0B04070
uniprot id: H8X174
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

1136231:CORT 0C04920
gene id: 1136231:CORT_0C04920
uniprot id: H8X306
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A10030
gene id: 1136231:CORT_0A10030
uniprot id: H8WX83
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

1136231:CORT 0A13040
gene id: 1136231:CORT_0A13040
uniprot id: H8WZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1136231:CORT 0G02640
gene id: 1136231:CORT_0G02640
uniprot id: H8XAU4
names: Similarity
messages: Belongs to the cyclin family.

1136231:CORT 0A02530
gene id: 1136231:CORT_0A02530
uniprot id: H8WW20
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

1136231:CORT 0A10730
gene id: 1136231:CORT_0A10730
uniprot id: H8WXF3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1136231:CORT 0C02510
gene id: 1136231:CORT_0C02510
uniprot id: H8X2S9
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0E06450
gene id: 1136231:CORT_0E06450
uniprot id: H8X7D2
names: Similarity
messages: Belongs to the SRR1 family.

1136231:CORT 0B03320
gene id: 1136231:CORT_0B03320
uniprot id: H8X102
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1136231:CORT 0C03480
gene id: 1136231:CORT_0C03480
uniprot id: H8X3T4
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

1136231:CORT 0D00470
gene id: 1136231:CORT_0D00470
uniprot id: H8X4F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AATF family.
messages: nucleolus

1136231:CORT 0A08540
gene id: 1136231:CORT_0A08540
uniprot id: H8WYC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

1136231:CORT 0C03220
gene id: 1136231:CORT_0C03220
uniprot id: H8X3Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

1136231:CORT 0H01100
gene id: 1136231:CORT_0H01100
uniprot id: H8XAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

1136231:CORT 0G02270
gene id: 1136231:CORT_0G02270
uniprot id: H8XAQ7
names: Similarity
messages: Belongs to the OPI10 family.

1136231:CORT 0G03730
gene id: 1136231:CORT_0G03730
uniprot id: H8XA72
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0D01400
gene id: 1136231:CORT_0D01400
uniprot id: H8X4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

1136231:CORT 0H02000
gene id: 1136231:CORT_0H02000
uniprot id: H8XB64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

1136231:CORT 0E00110
gene id: 1136231:CORT_0E00110
uniprot id: H8X6J1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: In the 2nd section; belongs to the EPSP synthase family.
messages: In the 3rd section; belongs to the shikimate kinase family.
messages: In the 4th section; belongs to the type-I 3-dehydroquinase family.
messages: In the C-terminal section; belongs to the shikimate dehydrogenase family.
messages: In the N-terminal section; belongs to the dehydroquinate synthase family.
messages: In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.

1136231:CORT 0E00690
gene id: 1136231:CORT_0E00690
uniprot id: H8X6P7
names: Similarity
messages: Belongs to the peptidase M20A family.

1136231:CORT 0D06520
gene id: 1136231:CORT_0D06520
uniprot id: H8X5M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

1136231:CORT 0C04780
gene id: 1136231:CORT_0C04780
uniprot id: H8X2Z2
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

1136231:CORT 0G03360
gene id: 1136231:CORT_0G03360
uniprot id: H8XA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

1136231:CORT 0A08480
gene id: 1136231:CORT_0A08480
uniprot id: H8WYB7
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1136231:CORT 0B06250
gene id: 1136231:CORT_0B06250
uniprot id: H8WZY9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1136231:CORT 0D03210
gene id: 1136231:CORT_0D03210
uniprot id: H8X572
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

1136231:CORT 0A12750
gene id: 1136231:CORT_0A12750
uniprot id: H8WZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1136231:CORT 0B11400
gene id: 1136231:CORT_0B11400
uniprot id: H8X2B7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

1136231:CORT 0A06810
gene id: 1136231:CORT_0A06810
uniprot id: H8WWS6
names: Similarity
messages: Belongs to the PTH family.

1136231:CORT 0F01790
gene id: 1136231:CORT_0F01790
uniprot id: H8X8D1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1136231:CORT 0A01550
gene id: 1136231:CORT_0A01550
uniprot id: H8WVS3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E00970
gene id: 1136231:CORT_0E00970
uniprot id: H8X6S5
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

1136231:CORT 0C03050
gene id: 1136231:CORT_0C03050
uniprot id: H8X3P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

1136231:CORT 0F01570
gene id: 1136231:CORT_0F01570
uniprot id: H8X985
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136231:CORT 0C05290
gene id: 1136231:CORT_0C05290
uniprot id: H8X343
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1136231:CORT 0E03350
gene id: 1136231:CORT_0E03350
uniprot id: H8X6Z5
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

1136231:CORT 0A06150
gene id: 1136231:CORT_0A06150
uniprot id: H8WY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1136231:CORT 0A10680
gene id: 1136231:CORT_0A10680
uniprot id: H8WXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0A10090
gene id: 1136231:CORT_0A10090
uniprot id: H8WX89
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1136231:CORT 0F02380
gene id: 1136231:CORT_0F02380
uniprot id: H8X8I8
names: Similarity
messages: Belongs to the TYW1 family.

1136231:CORT 0B04780
gene id: 1136231:CORT_0B04780
uniprot id: H8X1E6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A06720
gene id: 1136231:CORT_0A06720
uniprot id: H8WWR7
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

1136231:CORT 0E03510
gene id: 1136231:CORT_0E03510
uniprot id: H8X711
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

1136231:CORT 0A01990
gene id: 1136231:CORT_0A01990
uniprot id: H8WVW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YME2 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.

1136231:CORT 0A04160
gene id: 1136231:CORT_0A04160
uniprot id: H8WWI0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

1136231:CORT 0G01690
gene id: 1136231:CORT_0G01690
uniprot id: H8XAK6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1136231:CORT 0D02580
gene id: 1136231:CORT_0D02580
uniprot id: H8X511
names: Similarity
messages: Belongs to the PPP phosphatase family.

1136231:CORT 0B01910
gene id: 1136231:CORT_0B01910
uniprot id: H8X0M0
names: Similarity
messages: Belongs to the SNF8 family.

1136231:CORT 0G03990
gene id: 1136231:CORT_0G03990
uniprot id: H8XA99
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1136231:CORT 0B11300
gene id: 1136231:CORT_0B11300
uniprot id: H8X2A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies.

1136231:CORT 0A03340
gene id: 1136231:CORT_0A03340
uniprot id: H8WW98
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.

1136231:CORT 0A08960
gene id: 1136231:CORT_0A08960
uniprot id: H8WYG5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A10450
gene id: 1136231:CORT_0A10450
uniprot id: H8WXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

1136231:CORT 0A11150
gene id: 1136231:CORT_0A11150
uniprot id: H8WXJ4
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

1136231:CORT 0C01970
gene id: 1136231:CORT_0C01970
uniprot id: H8X2M6
names: Similarity
messages: Belongs to the FMO family.

1136231:CORT 0D00420
gene id: 1136231:CORT_0D00420
uniprot id: H8X5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat RTC1 family.
messages: May be involved in a process influencing telomere capping.
messages: Vacuole

1136231:CORT 0A01870
gene id: 1136231:CORT_0A01870
uniprot id: H8WVV4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E02010
gene id: 1136231:CORT_0E02010
uniprot id: H8X7K5
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A08260
gene id: 1136231:CORT_0A08260
uniprot id: H8WY96
names: Similarity
messages: Belongs to the eIF-2-alpha family.

1136231:CORT 0A01830
gene id: 1136231:CORT_0A01830
uniprot id: H8WVV0
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

1136231:CORT 0E00310
gene id: 1136231:CORT_0E00310
uniprot id: H8X6L1
names: Similarity
messages: Belongs to the beclin family.

1136231:CORT 0C02820
gene id: 1136231:CORT_0C02820
uniprot id: H8X3M0
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

1136231:CORT 0C00150
gene id: 1136231:CORT_0C00150
uniprot id: H8X3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0A10600
gene id: 1136231:CORT_0A10600
uniprot id: H8WXE0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

1136231:CORT 0D03950
gene id: 1136231:CORT_0D03950
uniprot id: H8X5Y7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

1136231:CORT 0H02580
gene id: 1136231:CORT_0H02580
uniprot id: H8XBB9
names: Similarity
messages: Belongs to the MYBBP1A family.

1136231:CORT 0B10990
gene id: 1136231:CORT_0B10990
uniprot id: H8X276
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.

1136231:CORT 0G00120
gene id: 1136231:CORT_0G00120
uniprot id: H8X9N7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F01090
gene id: 1136231:CORT_0F01090
uniprot id: H8X938
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

1136231:CORT 0C04350
gene id: 1136231:CORT_0C04350
uniprot id: H8X420
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1136231:CORT 0A03930
gene id: 1136231:CORT_0A03930
uniprot id: H8WWF7
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1136231:CORT 0B07090
gene id: 1136231:CORT_0B07090
uniprot id: H8X1L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1136231:CORT 0G00400
gene id: 1136231:CORT_0G00400
uniprot id: H8X9R4
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0E05260
gene id: 1136231:CORT_0E05260
uniprot id: H8X812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

1136231:CORT 0B02260
gene id: 1136231:CORT_0B02260
uniprot id: H8X0Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1136231:CORT 0A08490
gene id: 1136231:CORT_0A08490
uniprot id: H8WYB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0B09270
gene id: 1136231:CORT_0B09270
uniprot id: H8X0B9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C03110
gene id: 1136231:CORT_0C03110
uniprot id: H8X3P9
names: Similarity
messages: Belongs to the WD repeat mio family.

1136231:CORT 0D07260
gene id: 1136231:CORT_0D07260
uniprot id: H8X6E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRT14 family.
messages: Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
messages: nucleolus

1136231:CORT 0G01890
gene id: 1136231:CORT_0G01890
uniprot id: H8XAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1136231:CORT 0C02750
gene id: 1136231:CORT_0C02750
uniprot id: H8X3L3
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0B08590
gene id: 1136231:CORT_0B08590
uniprot id: H8X051
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0A04210
gene id: 1136231:CORT_0A04210
uniprot id: H8WWI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0H00580
gene id: 1136231:CORT_0H00580
uniprot id: H8XBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

1136231:CORT 0E02140
gene id: 1136231:CORT_0E02140
uniprot id: H8X7L6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1136231:CORT 0E06460
gene id: 1136231:CORT_0E06460
uniprot id: H8X7D3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1136231:CORT 0A04930
gene id: 1136231:CORT_0A04930
uniprot id: H8WXT4
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0G03120
gene id: 1136231:CORT_0G03120
uniprot id: H8XA13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0G00890
gene id: 1136231:CORT_0G00890
uniprot id: H8X9W0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0A12080
gene id: 1136231:CORT_0A12080
uniprot id: H8WYW1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1136231:CORT 0G00550
gene id: 1136231:CORT_0G00550
uniprot id: H8X9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

1136231:CORT 0G04450
gene id: 1136231:CORT_0G04450
uniprot id: H8XAE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0B04660
gene id: 1136231:CORT_0B04660
uniprot id: H8X1D4
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

1136231:CORT 0C01220
gene id: 1136231:CORT_0C01220
uniprot id: H8X2F2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1136231:CORT 0C01480
gene id: 1136231:CORT_0C01480
uniprot id: H8X2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM MRD1 family.
messages: Nucleus

1136231:CORT 0G01040
gene id: 1136231:CORT_0G01040
uniprot id: H8X9X5
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A02350
gene id: 1136231:CORT_0A02350
uniprot id: H8WW02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure
messages: Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

1136231:CORT 0E03720
gene id: 1136231:CORT_0E03720
uniprot id: H8X732
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1136231:CORT 0A00740
gene id: 1136231:CORT_0A00740
uniprot id: H8WVJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1136231:CORT 0C03430
gene id: 1136231:CORT_0C03430
uniprot id: H8X3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0D05280
gene id: 1136231:CORT_0D05280
uniprot id: H8X6B9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E01260
gene id: 1136231:CORT_0E01260
uniprot id: H8X6V4
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

1136231:CORT 0E02890
gene id: 1136231:CORT_0E02890
uniprot id: H8X7U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

1136231:CORT 0C04710
gene id: 1136231:CORT_0C04710
uniprot id: H8X2Y5
names: Subunit
messages: Consists of at least two heavy chains and a number of intermediate and light chains.

1136231:CORT 0B02310
gene id: 1136231:CORT_0B02310
uniprot id: H8X0Q9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

1136231:CORT 0B04710
gene id: 1136231:CORT_0B04710
uniprot id: H8X1D9
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1136231:CORT 0B05820
gene id: 1136231:CORT_0B05820
uniprot id: H8WZU6
names: Similarity
messages: Belongs to the MAK16 family.

1136231:CORT 0B03530
gene id: 1136231:CORT_0B03530
uniprot id: H8X122
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0D06290
gene id: 1136231:CORT_0D06290
uniprot id: H8X5K8
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1136231:CORT 0G03690
gene id: 1136231:CORT_0G03690
uniprot id: H8XA68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression.

1136231:CORT 0A02700
gene id: 1136231:CORT_0A02700
uniprot id: H8WW36
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1136231:CORT 0D03940
gene id: 1136231:CORT_0D03940
uniprot id: H8X5Y6
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

1136231:CORT 0H00830
gene id: 1136231:CORT_0H00830
uniprot id: H8XBL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

1136231:CORT 0A09050
gene id: 1136231:CORT_0A09050
uniprot id: H8WYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Preautophagosomal structure membrane

1136231:CORT 0C02290
gene id: 1136231:CORT_0C02290
uniprot id: H8X2Q8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A07320
gene id: 1136231:CORT_0A07320
uniprot id: H8WWX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1136231:CORT 0H00540
gene id: 1136231:CORT_0H00540
uniprot id: H8XBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

1136231:CORT 0B10060
gene id: 1136231:CORT_0B10060
uniprot id: H8WWA7
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

1136231:CORT 0E00860
gene id: 1136231:CORT_0E00860
uniprot id: H8X6R4
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

1136231:CORT 0C04380
gene id: 1136231:CORT_0C04380
uniprot id: H8X423
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1136231:CORT 0F03640
gene id: 1136231:CORT_0F03640
uniprot id: H8X9C1
names: Similarity
messages: Belongs to the MOG1 family.

1136231:CORT 0E00950
gene id: 1136231:CORT_0E00950
uniprot id: H8X6S3
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

1136231:CORT 0A10510
gene id: 1136231:CORT_0A10510
uniprot id: H8WXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

1136231:CORT 0G03210
gene id: 1136231:CORT_0G03210
uniprot id: H8XA21
names: Function
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0H01920
gene id: 1136231:CORT_0H01920
uniprot id: H8XB56
names: Similarity
messages: Belongs to the CNOT9 family.

1136231:CORT 0C05810
gene id: 1136231:CORT_0C05810
uniprot id: H8X394
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1136231:CORT 0C04030
gene id: 1136231:CORT_0C04030
uniprot id: H8X3Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

1136231:CORT 0B01280
gene id: 1136231:CORT_0B01280
uniprot id: H8WZH9
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0F01670
gene id: 1136231:CORT_0F01670
uniprot id: H8X995
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136231:CORT 0D04340
gene id: 1136231:CORT_0D04340
uniprot id: H8X626
names: Similarity
messages: Belongs to the hexokinase family.

1136231:CORT 0B02450
gene id: 1136231:CORT_0B02450
uniprot id: H8X0S1
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

1136231:CORT 0B09490
gene id: 1136231:CORT_0B09490
uniprot id: H8X0E1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

1136231:CORT 0B05590
gene id: 1136231:CORT_0B05590
uniprot id: H8WZS2
names: Similarity
messages: Belongs to the PHF5 family.

1136231:CORT 0B06790
gene id: 1136231:CORT_0B06790
uniprot id: H8X1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

1136231:CORT 0F02750
gene id: 1136231:CORT_0F02750
uniprot id: H8X8M4
names: Similarity
messages: Belongs to the lysophospholipase family.

1136231:CORT 0D04900
gene id: 1136231:CORT_0D04900
uniprot id: H8X682
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus

1136231:CORT 0A06060
gene id: 1136231:CORT_0A06060
uniprot id: H8WY46
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0C06210
gene id: 1136231:CORT_0C06210
uniprot id: H8X442
names: Similarity
messages: Belongs to the peptidase S8 family.

1136231:CORT 0C03040
gene id: 1136231:CORT_0C03040
uniprot id: H8X3P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

1136231:CORT 0D06180
gene id: 1136231:CORT_0D06180
uniprot id: H8X5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

1136231:CORT 0E03610
gene id: 1136231:CORT_0E03610
uniprot id: H8X721
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H02490
gene id: 1136231:CORT_0H02490
uniprot id: H8XBB0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0E06240
gene id: 1136231:CORT_0E06240
uniprot id: H8X8A7
names: Similarity
messages: Belongs to the multicopper oxidase family.

1136231:CORT 0B00300
gene id: 1136231:CORT_0B00300
uniprot id: H8WZ85
names: Function
names: Similarity
messages: Belongs to the EAF1 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.

1136231:CORT 0C01580
gene id: 1136231:CORT_0C01580
uniprot id: H8X2I8
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

1136231:CORT 0B02820
gene id: 1136231:CORT_0B02820
uniprot id: H8X0V8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

1136231:CORT 0F00240
gene id: 1136231:CORT_0F00240
uniprot id: H8X8V5
names: Similarity
messages: Belongs to the IlvD/Edd family.

1136231:CORT 0H00510
gene id: 1136231:CORT_0H00510
uniprot id: H8XBI0
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

1136231:CORT 0D04020
gene id: 1136231:CORT_0D04020
uniprot id: H8X5Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

1136231:CORT 0H01370
gene id: 1136231:CORT_0H01370
uniprot id: H8XB02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1136231:CORT 0A05680
gene id: 1136231:CORT_0A05680
uniprot id: H8WY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

1136231:CORT 0B00180
gene id: 1136231:CORT_0B00180
uniprot id: H8WZ73
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

1136231:CORT 0D05040
gene id: 1136231:CORT_0D05040
uniprot id: H8X696
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

1136231:CORT 0D02670
gene id: 1136231:CORT_0D02670
uniprot id: H8X519
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

1136231:CORT 0A13090
gene id: 1136231:CORT_0A13090
uniprot id: H8WXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
messages: Nucleus

1136231:CORT 0A01470
gene id: 1136231:CORT_0A01470
uniprot id: H8WVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

1136231:CORT 0D00480
gene id: 1136231:CORT_0D00480
uniprot id: H8X4F4
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A08170
gene id: 1136231:CORT_0A08170
uniprot id: H8WY87
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1136231:CORT 0E02690
gene id: 1136231:CORT_0E02690
uniprot id: H8X7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

1136231:CORT 0F04610
gene id: 1136231:CORT_0F04610
uniprot id: H8X9M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

1136231:CORT 0A00920
gene id: 1136231:CORT_0A00920
uniprot id: H8WVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Mitochondrion inner membrane

1136231:CORT 0F04260
gene id: 1136231:CORT_0F04260
uniprot id: H8X9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1136231:CORT 0B00680
gene id: 1136231:CORT_0B00680
uniprot id: H8WZC1
names: Similarity
messages: Belongs to the aspartokinase family.

1136231:CORT 0G01190
gene id: 1136231:CORT_0G01190
uniprot id: H8XAF7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0C04960
gene id: 1136231:CORT_0C04960
uniprot id: H8X310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

1136231:CORT 0B05890
gene id: 1136231:CORT_0B05890
uniprot id: H8WZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

1136231:CORT 0A04690
gene id: 1136231:CORT_0A04690
uniprot id: H8WXR0
names: Similarity
messages: Belongs to the lysophospholipase family.

1136231:CORT 0E01940
gene id: 1136231:CORT_0E01940
uniprot id: H8X7J7
names: Function
names: Subcellular Location Annotation
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion

1136231:CORT 0D05520
gene id: 1136231:CORT_0D05520
uniprot id: H8X5D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

1136231:CORT 0A12310
gene id: 1136231:CORT_0A12310
uniprot id: H8WYY4
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

1136231:CORT 0A12320
gene id: 1136231:CORT_0A12320
uniprot id: H8WYY5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

1136231:CORT 0D02610
gene id: 1136231:CORT_0D02610
uniprot id: H8X513
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0G04340
gene id: 1136231:CORT_0G04340
uniprot id: H8XAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

1136231:CORT 0D00510
gene id: 1136231:CORT_0D00510
uniprot id: H8X4F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Mitochondrion inner membrane

1136231:CORT 0E00240
gene id: 1136231:CORT_0E00240
uniprot id: H8X6K4
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

1136231:CORT 0D05910
gene id: 1136231:CORT_0D05910
uniprot id: H8X5H3
names: Similarity
messages: Belongs to the PP2C family.

1136231:CORT 0A04480
gene id: 1136231:CORT_0A04480
uniprot id: H8WWL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus
messages: telomere

1136231:CORT 0F00630
gene id: 1136231:CORT_0F00630
uniprot id: H8X8Z4
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

1136231:CORT 0A11510
gene id: 1136231:CORT_0A11510
uniprot id: H8WYQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0D05860
gene id: 1136231:CORT_0D05860
uniprot id: H8X5G8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1136231:CORT 0E00760
gene id: 1136231:CORT_0E00760
uniprot id: H8X6Q4
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

1136231:CORT 0G03470
gene id: 1136231:CORT_0G03470
uniprot id: H8XA46
names: Similarity
messages: Belongs to the cytochrome b5 family.

1136231:CORT 0E03620
gene id: 1136231:CORT_0E03620
uniprot id: H8X722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1136231:CORT 0F00730
gene id: 1136231:CORT_0F00730
uniprot id: H8X904
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

1136231:CORT 0C02840
gene id: 1136231:CORT_0C02840
uniprot id: H8X3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1136231:CORT 0D07230
gene id: 1136231:CORT_0D07230
uniprot id: H8X6E5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136231:CORT 0C06310
gene id: 1136231:CORT_0C06310
uniprot id: H8X453
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

1136231:CORT 0F00590
gene id: 1136231:CORT_0F00590
uniprot id: H8X8Z0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1136231:CORT 0A06780
gene id: 1136231:CORT_0A06780
uniprot id: H8WWS3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A08110
gene id: 1136231:CORT_0A08110
uniprot id: H8WY81
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

1136231:CORT 0A01500
gene id: 1136231:CORT_0A01500
uniprot id: H8WVR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1136231:CORT 0E04680
gene id: 1136231:CORT_0E04680
uniprot id: H8X7C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0B02770
gene id: 1136231:CORT_0B02770
uniprot id: H8X0V3
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1136231:CORT 0G00200
gene id: 1136231:CORT_0G00200
uniprot id: H8X9P5
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.

1136231:CORT 0E03790
gene id: 1136231:CORT_0E03790
uniprot id: H8X739
names: Subcellular Location Annotation
messages: nuclear pore complex

1136231:CORT 0A11540
gene id: 1136231:CORT_0A11540
uniprot id: H8WYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

1136231:CORT 0B04430
gene id: 1136231:CORT_0B04430
uniprot id: H8X1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1136231:CORT 0G03750
gene id: 1136231:CORT_0G03750
uniprot id: H8XA74
names: Similarity
messages: Belongs to the amidase family.

1136231:CORT 0A10120
gene id: 1136231:CORT_0A10120
uniprot id: H8WX92
names: Function
names: Similarity
messages: Belongs to the ETT1 family.
messages: Required for correct translation termination and probably involved in regulation of hypoxic gene expression.

1136231:CORT 0F04460
gene id: 1136231:CORT_0F04460
uniprot id: H8X9K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

1136231:CORT 0B06440
gene id: 1136231:CORT_0B06440
uniprot id: H8X008
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

1136231:CORT 0F01680
gene id: 1136231:CORT_0F01680
uniprot id: H8X996
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.

1136231:CORT 0B01460
gene id: 1136231:CORT_0B01460
uniprot id: H8WZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

1136231:CORT 0A03600
gene id: 1136231:CORT_0A03600
uniprot id: H8WWC4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1136231:CORT 0F01520
gene id: 1136231:CORT_0F01520
uniprot id: H8X980
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

1136231:CORT 0F02840
gene id: 1136231:CORT_0F02840
uniprot id: H8X8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1136231:CORT 0E05470
gene id: 1136231:CORT_0E05470
uniprot id: H8X833
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

1136231:CORT 0E06440
gene id: 1136231:CORT_0E06440
uniprot id: H8X7D1
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A08880
gene id: 1136231:CORT_0A08880
uniprot id: H8WYF7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1136231:CORT 0B09720
gene id: 1136231:CORT_0B09720
uniprot id: H8X0G4
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1136231:CORT 0G00770
gene id: 1136231:CORT_0G00770
uniprot id: H8X9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane

1136231:CORT 0A10890
gene id: 1136231:CORT_0A10890
uniprot id: H8WXG8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C01210
gene id: 1136231:CORT_0C01210
uniprot id: H8X2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

1136231:CORT 0C03960
gene id: 1136231:CORT_0C03960
uniprot id: H8X3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0C03900
gene id: 1136231:CORT_0C03900
uniprot id: H8X3X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1136231:CORT 0C07170
gene id: 1136231:CORT_0C07170
uniprot id: H8X4D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1136231:CORT 0B03050
gene id: 1136231:CORT_0B03050
uniprot id: H8X0X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1136231:CORT 0D05430
gene id: 1136231:CORT_0D05430
uniprot id: H8X6D4
names: Similarity
messages: Belongs to the LCL2 family.

1136231:CORT 0B09680
gene id: 1136231:CORT_0B09680
uniprot id: H8X0G0
names: Similarity
messages: Belongs to the 14-3-3 family.

1136231:CORT 0D00390
gene id: 1136231:CORT_0D00390
uniprot id: H8X5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

1136231:CORT 0A02770
gene id: 1136231:CORT_0A02770
uniprot id: H8WW43
names: Similarity
messages: Belongs to the sorting nexin family.

1136231:CORT 0A10920
gene id: 1136231:CORT_0A10920
uniprot id: H8WXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.

1136231:CORT 0F04590
gene id: 1136231:CORT_0F04590
uniprot id: H8X9L7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

1136231:CORT 0F03310
gene id: 1136231:CORT_0F03310
uniprot id: H8X8T0
names: Similarity
messages: Belongs to the AHA1 family.

1136231:CORT 0E01580
gene id: 1136231:CORT_0E01580
uniprot id: H8X7G2
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

1136231:CORT 0C06960
gene id: 1136231:CORT_0C06960
uniprot id: H8X4B5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1136231:CORT 0E02090
gene id: 1136231:CORT_0E02090
uniprot id: H8X7L2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1136231:CORT 0E04010
gene id: 1136231:CORT_0E04010
uniprot id: H8X760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0F02870
gene id: 1136231:CORT_0F02870
uniprot id: H8X8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B10200
gene id: 1136231:CORT_0B10200
uniprot id: H8X203
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1136231:CORT 0E05270
gene id: 1136231:CORT_0E05270
uniprot id: H8X813
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1136231:CORT 0E03030
gene id: 1136231:CORT_0E03030
uniprot id: H8X7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0D04990
gene id: 1136231:CORT_0D04990
uniprot id: H8X691
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

1136231:CORT 0C01260
gene id: 1136231:CORT_0C01260
uniprot id: H8X2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM18/AIM46 family.
messages: Mitochondrion

1136231:CORT 0A06910
gene id: 1136231:CORT_0A06910
uniprot id: H8WWT6
names: Similarity
messages: Belongs to the EFR3 family.

1136231:CORT 0A09290
gene id: 1136231:CORT_0A09290
uniprot id: H8WYJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

1136231:CORT 0C03880
gene id: 1136231:CORT_0C03880
uniprot id: H8X3X4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family. PreP subfamily.
messages: Mitochondrion intermembrane space
messages: Mitochondrion matrix
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

1136231:CORT 0C06540
gene id: 1136231:CORT_0C06540
uniprot id: H8X475
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1136231:CORT 0C03760
gene id: 1136231:CORT_0C03760
uniprot id: H8X3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0A10440
gene id: 1136231:CORT_0A10440
uniprot id: H8WXC4
names: Similarity
messages: Belongs to the Mo25 family.

1136231:CORT 0A06200
gene id: 1136231:CORT_0A06200
uniprot id: H8WY60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

1136231:CORT 0E03010
gene id: 1136231:CORT_0E03010
uniprot id: H8X7V4
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0B05240
gene id: 1136231:CORT_0B05240
uniprot id: H8WZN7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E04060
gene id: 1136231:CORT_0E04060
uniprot id: H8X765
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 1 family.
messages: Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

1136231:CORT 0E04990
gene id: 1136231:CORT_0E04990
uniprot id: H8X7Y4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1136231:CORT 0D03930
gene id: 1136231:CORT_0D03930
uniprot id: H8X5Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

1136231:CORT 0A13150
gene id: 1136231:CORT_0A13150
uniprot id: H8WXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0F01010
gene id: 1136231:CORT_0F01010
uniprot id: H8X931
names: Subcellular Location Annotation
messages: cis-Golgi network

1136231:CORT 0A03660
gene id: 1136231:CORT_0A03660
uniprot id: H8WWD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

1136231:CORT 0G02890
gene id: 1136231:CORT_0G02890
uniprot id: H8X9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat TRM82 family.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

1136231:CORT 0G01300
gene id: 1136231:CORT_0G01300
uniprot id: H8XAG8
names: Similarity
messages: Belongs to the lysophospholipase family.

1136231:CORT 0E03860
gene id: 1136231:CORT_0E03860
uniprot id: H8X745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1136231:CORT 0G04130
gene id: 1136231:CORT_0G04130
uniprot id: H8XAB3
names: Similarity
messages: Belongs to the UFD1 family.

1136231:CORT 0H00930
gene id: 1136231:CORT_0H00930
uniprot id: H8XAW1
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1136231:CORT 0A13000
gene id: 1136231:CORT_0A13000
uniprot id: H8WZ51
names: Similarity
messages: Belongs to the PGA52 family.

1136231:CORT 0B05720
gene id: 1136231:CORT_0B05720
uniprot id: H8WZT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1136231:CORT 0A11880
gene id: 1136231:CORT_0A11880
uniprot id: H8WYU1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1136231:CORT 0G01020
gene id: 1136231:CORT_0G01020
uniprot id: H8X9X3
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Cytoplasm
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

1136231:CORT 0B10070
gene id: 1136231:CORT_0B10070
uniprot id: H8X1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Mitochondrion inner membrane

1136231:CORT 0B07890
gene id: 1136231:CORT_0B07890
uniprot id: H8X1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IML1 family.
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0F00150
gene id: 1136231:CORT_0F00150
uniprot id: H8X8U7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1136231:CORT 0E06390
gene id: 1136231:CORT_0E06390
uniprot id: H8X8C2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

1136231:CORT 0E01720
gene id: 1136231:CORT_0E01720
uniprot id: H8X7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

1136231:CORT 0E06100
gene id: 1136231:CORT_0E06100
uniprot id: H8X893
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

1136231:CORT 0E01640
gene id: 1136231:CORT_0E01640
uniprot id: H8X7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane

1136231:CORT 0H02640
gene id: 1136231:CORT_0H02640
uniprot id: H8XBC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0D07130
gene id: 1136231:CORT_0D07130
uniprot id: H8X5T8
names: Similarity
messages: Belongs to the PGA52 family.

1136231:CORT 0H00460
gene id: 1136231:CORT_0H00460
uniprot id: H8XBH5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

1136231:CORT 0F01450
gene id: 1136231:CORT_0F01450
uniprot id: H8X973
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

1136231:CORT 0C04600
gene id: 1136231:CORT_0C04600
uniprot id: H8X2X4
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1136231:CORT 0F03140
gene id: 1136231:CORT_0F03140
uniprot id: H8X8R3
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

1136231:CORT 0A00430
gene id: 1136231:CORT_0A00430
uniprot id: H8WVG4
names: Similarity
messages: Belongs to the cullin family.

1136231:CORT 0H00150
gene id: 1136231:CORT_0H00150
uniprot id: H8XBE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

1136231:CORT 0H02270
gene id: 1136231:CORT_0H02270
uniprot id: H8XB88
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

1136231:CORT 0H02650
gene id: 1136231:CORT_0H02650
uniprot id: H8XBC6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0A13490
gene id: 1136231:CORT_0A13490
uniprot id: H8WXQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

1136231:CORT 0D04630
gene id: 1136231:CORT_0D04630
uniprot id: H8X655
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

1136231:CORT 0A04760
gene id: 1136231:CORT_0A04760
uniprot id: H8WXR7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136231:CORT 0E02570
gene id: 1136231:CORT_0E02570
uniprot id: H8X7Q8
names: Similarity
messages: Belongs to the cytidylyltransferase family.

1136231:CORT 0G01270
gene id: 1136231:CORT_0G01270
uniprot id: H8XAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1136231:CORT 0F01230
gene id: 1136231:CORT_0F01230
uniprot id: H8X952
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

1136231:CORT 0F00400
gene id: 1136231:CORT_0F00400
uniprot id: H8X8X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

1136231:CORT 0E00430
gene id: 1136231:CORT_0E00430
uniprot id: H8X6M2
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

1136231:CORT 0C05330
gene id: 1136231:CORT_0C05330
uniprot id: H8X347
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0A03480
gene id: 1136231:CORT_0A03480
uniprot id: H8WWB2
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

1136231:CORT 0H01520
gene id: 1136231:CORT_0H01520
uniprot id: H8XB17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

1136231:CORT 0C05270
gene id: 1136231:CORT_0C05270
uniprot id: H8X341
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1136231:CORT 0D05350
gene id: 1136231:CORT_0D05350
uniprot id: H8X6C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

1136231:CORT 0E00710
gene id: 1136231:CORT_0E00710
uniprot id: H8X6P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
messages: Membrane

1136231:CORT 0B07930
gene id: 1136231:CORT_0B07930
uniprot id: H8X1U2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C05340
gene id: 1136231:CORT_0C05340
uniprot id: H8X348
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1136231:CORT 0H00970
gene id: 1136231:CORT_0H00970
uniprot id: H8XAW5
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1136231:CORT 0D00670
gene id: 1136231:CORT_0D00670
uniprot id: H8X4H3
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1136231:CORT 0G00910
gene id: 1136231:CORT_0G00910
uniprot id: H8X9W2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1136231:CORT 0B04300
gene id: 1136231:CORT_0B04300
uniprot id: H8X197
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1136231:CORT 0A07660
gene id: 1136231:CORT_0A07660
uniprot id: H8WX12
names: Similarity
messages: Belongs to the APC10 family.

1136231:CORT 0A10290
gene id: 1136231:CORT_0A10290
uniprot id: H8WXA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

1136231:CORT 0C01740
gene id: 1136231:CORT_0C01740
uniprot id: H8X2K4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

1136231:CORT 0C05090
gene id: 1136231:CORT_0C05090
uniprot id: H8X322
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

1136231:CORT 0D04970
gene id: 1136231:CORT_0D04970
uniprot id: H8X689
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

1136231:CORT 0A12010
gene id: 1136231:CORT_0A12010
uniprot id: H8WYV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
messages: Interacts with CHS3.
messages: Membrane

1136231:CORT 0G04140
gene id: 1136231:CORT_0G04140
uniprot id: H8XAB4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136231:CORT 0A05620
gene id: 1136231:CORT_0A05620
uniprot id: H8WY02
names: Similarity
messages: Belongs to the BMT family.

1136231:CORT 0F03270
gene id: 1136231:CORT_0F03270
uniprot id: H8X8S6
names: Similarity
messages: Belongs to the VPS72/YL1 family.

1136231:CORT 0E03870
gene id: 1136231:CORT_0E03870
uniprot id: H8X746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1136231:CORT 0A09530
gene id: 1136231:CORT_0A09530
uniprot id: H8WYM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane

1136231:CORT 0F04670
gene id: 1136231:CORT_0F04670
uniprot id: H8X9M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0B00270
gene id: 1136231:CORT_0B00270
uniprot id: H8WZ82
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A08600
gene id: 1136231:CORT_0A08600
uniprot id: H8WYC9
names: Similarity
messages: Belongs to the DOCK family.

1136231:CORT 0D05230
gene id: 1136231:CORT_0D05230
uniprot id: H8X6B4
names: Similarity
messages: Belongs to the TCP11 family.

1136231:CORT 0C03720
gene id: 1136231:CORT_0C03720
uniprot id: H8X3V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRG family.
messages: Nucleus

1136231:CORT 0G02290
gene id: 1136231:CORT_0G02290
uniprot id: H8XAQ9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1136231:CORT 0C06160
gene id: 1136231:CORT_0C06160
uniprot id: H8X437
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0D06080
gene id: 1136231:CORT_0D06080
uniprot id: H8X5I8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1136231:CORT 0F00280
gene id: 1136231:CORT_0F00280
uniprot id: H8X8V9
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

1136231:CORT 0B02080
gene id: 1136231:CORT_0B02080
uniprot id: H8X0N7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G00660
gene id: 1136231:CORT_0G00660
uniprot id: H8X9T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

1136231:CORT 0A02450
gene id: 1136231:CORT_0A02450
uniprot id: H8WW12
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

1136231:CORT 0F02760
gene id: 1136231:CORT_0F02760
uniprot id: H8X8M5
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1136231:CORT 0A02600
gene id: 1136231:CORT_0A02600
uniprot id: H8WW27
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

1136231:CORT 0E03090
gene id: 1136231:CORT_0E03090
uniprot id: H8X6X0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

1136231:CORT 0A00710
gene id: 1136231:CORT_0A00710
uniprot id: H8WVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0D02390
gene id: 1136231:CORT_0D02390
uniprot id: H8X4Z4
names: Similarity
messages: Belongs to the AAA ATPase family.

1136231:CORT 0B04040
gene id: 1136231:CORT_0B04040
uniprot id: H8X171
names: Similarity
messages: Belongs to the VPS37 family.

1136231:CORT 0E02500
gene id: 1136231:CORT_0E02500
uniprot id: H8X7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0A12490
gene id: 1136231:CORT_0A12490
uniprot id: H8WZ02
names: Similarity
messages: Belongs to the NifU family.

1136231:CORT 0B00230
gene id: 1136231:CORT_0B00230
uniprot id: H8WZ78
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

1136231:CORT 0C03535
gene id: 1136231:CORT_0C03535
uniprot id: H8X3U0
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0A11870
gene id: 1136231:CORT_0A11870
uniprot id: H8WYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

1136231:CORT 0A03330
gene id: 1136231:CORT_0A03330
uniprot id: H8WW97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1136231:CORT 0E05730
gene id: 1136231:CORT_0E05730
uniprot id: H8X858
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1136231:CORT 0C00620
gene id: 1136231:CORT_0C00620
uniprot id: H8X3G7
names: Similarity
messages: Belongs to the RRP1 family.

1136231:CORT 0A04140
gene id: 1136231:CORT_0A04140
uniprot id: H8WWH8
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B05600
gene id: 1136231:CORT_0B05600
uniprot id: H8WZS3
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B08020
gene id: 1136231:CORT_0B08020
uniprot id: H8X1V1
names: Similarity
messages: Belongs to the Rho GDI family.

1136231:CORT 0A07440
gene id: 1136231:CORT_0A07440
uniprot id: H8WWY9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D00190
gene id: 1136231:CORT_0D00190
uniprot id: H8X5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

1136231:CORT 0B10700
gene id: 1136231:CORT_0B10700
uniprot id: H8X250
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

1136231:CORT 0G03900
gene id: 1136231:CORT_0G03900
uniprot id: H8XA90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

1136231:CORT 0A13360
gene id: 1136231:CORT_0A13360
uniprot id: H8WXP6
names: Similarity
messages: Belongs to the cyclin family.

1136231:CORT 0A13320
gene id: 1136231:CORT_0A13320
uniprot id: H8WXP2
names: Similarity
messages: Belongs to the sorting nexin family.

1136231:CORT 0A02990
gene id: 1136231:CORT_0A02990
uniprot id: H8WW64
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1136231:CORT 0A03240
gene id: 1136231:CORT_0A03240
uniprot id: H8WW88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

1136231:CORT 0A11930
gene id: 1136231:CORT_0A11930
uniprot id: H8WYU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

1136231:CORT 0D07510
gene id: 1136231:CORT_0D07510
uniprot id: H8X6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

1136231:CORT 0B06710
gene id: 1136231:CORT_0B06710
uniprot id: H8X1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

1136231:CORT 0B04870
gene id: 1136231:CORT_0B04870
uniprot id: H8X1F5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1136231:CORT 0H02670
gene id: 1136231:CORT_0H02670
uniprot id: H8XBC8
names: Subcellular Location Annotation
messages: nuclear pore complex

1136231:CORT 0A10480
gene id: 1136231:CORT_0A10480
uniprot id: H8WXC8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

1136231:CORT 0B10750
gene id: 1136231:CORT_0B10750
uniprot id: H8X255
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1136231:CORT 0F02250
gene id: 1136231:CORT_0F02250
uniprot id: H8X8H5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1136231:CORT 0E05360
gene id: 1136231:CORT_0E05360
uniprot id: H8X822
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1136231:CORT 0E02510
gene id: 1136231:CORT_0E02510
uniprot id: H8X7Q3
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0H02440
gene id: 1136231:CORT_0H02440
uniprot id: H8XBA5
names: Similarity
messages: Belongs to the CCDC25 family.

1136231:CORT 0C01190
gene id: 1136231:CORT_0C01190
uniprot id: H8X2E9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

1136231:CORT 0A02740
gene id: 1136231:CORT_0A02740
uniprot id: H8WW40
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

1136231:CORT 0H01120
gene id: 1136231:CORT_0H01120
uniprot id: H8XAY0
names: Similarity
messages: Belongs to the RMD1/sif2 family.

1136231:CORT 0A04180
gene id: 1136231:CORT_0A04180
uniprot id: H8WWI2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E03050
gene id: 1136231:CORT_0E03050
uniprot id: H8X7V8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B02580
gene id: 1136231:CORT_0B02580
uniprot id: H8X0T4
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

1136231:CORT 0A05610
gene id: 1136231:CORT_0A05610
uniprot id: H8WY01
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

1136231:CORT 0C01710
gene id: 1136231:CORT_0C01710
uniprot id: H8X2K1
names: Subcellular Location Annotation
messages: Peroxisome membrane

1136231:CORT 0A11940
gene id: 1136231:CORT_0A11940
uniprot id: H8WYU7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E02340
gene id: 1136231:CORT_0E02340
uniprot id: H8X7N6
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1136231:CORT 0A08210
gene id: 1136231:CORT_0A08210
uniprot id: H8WY91
names: Similarity
messages: Belongs to the RutC family.

1136231:CORT 0F04700
gene id: 1136231:CORT_0F04700
uniprot id: H8X9M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0D07360
gene id: 1136231:CORT_0D07360
uniprot id: H8X6F8
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B06320
gene id: 1136231:CORT_0B06320
uniprot id: H8WZZ6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1136231:CORT 0D02710
gene id: 1136231:CORT_0D02710
uniprot id: H8X523
names: Function
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0G03710
gene id: 1136231:CORT_0G03710
uniprot id: H8XA70
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

1136231:CORT 0E00830
gene id: 1136231:CORT_0E00830
uniprot id: H8X6R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0E05300
gene id: 1136231:CORT_0E05300
uniprot id: H8X816
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

1136231:CORT 0B04280
gene id: 1136231:CORT_0B04280
uniprot id: H8X195
names: Similarity
messages: Belongs to the KRI1 family.

1136231:CORT 0B03250
gene id: 1136231:CORT_0B03250
uniprot id: H8X0Z5
names: Similarity
messages: Belongs to the RMD1/sif2 family.

1136231:CORT 0F04720
gene id: 1136231:CORT_0F04720
uniprot id: H8X9N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

1136231:CORT 0B09440
gene id: 1136231:CORT_0B09440
uniprot id: H8X0D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0A09040
gene id: 1136231:CORT_0A09040
uniprot id: H8WYH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1136231:CORT 0C06610
gene id: 1136231:CORT_0C06610
uniprot id: H8X482
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F00900
gene id: 1136231:CORT_0F00900
uniprot id: H8X921
names: Similarity
messages: Belongs to the TIP41 family.

1136231:CORT 0C01280
gene id: 1136231:CORT_0C01280
uniprot id: H8X2F8
names: Similarity
messages: Belongs to the TTI2 family.

1136231:CORT 0F02010
gene id: 1136231:CORT_0F02010
uniprot id: H8X8F2
names: Similarity
messages: Belongs to the peptidase M20A family.

1136231:CORT 0B09190
gene id: 1136231:CORT_0B09190
uniprot id: H8X0B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family.
messages: Mitochondrion
messages: N-acetylglutamate synthase involved in arginine biosynthesis.

1136231:CORT 0B09690
gene id: 1136231:CORT_0B09690
uniprot id: H8X0G1
names: Function
names: Similarity
messages: Belongs to the peptidase M24 family.
messages: Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm.

1136231:CORT 0E06500
gene id: 1136231:CORT_0E06500
uniprot id: H8X7D7
names: Subcellular Location Annotation
messages: nuclear pore complex

1136231:CORT 0A10780
gene id: 1136231:CORT_0A10780
uniprot id: H8WXF7
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0H01060
gene id: 1136231:CORT_0H01060
uniprot id: H8XAX4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0G00600
gene id: 1136231:CORT_0G00600
uniprot id: H8X9T3
names: Similarity
messages: Belongs to the FAH family.

1136231:CORT 0E05050
gene id: 1136231:CORT_0E05050
uniprot id: H8X7Z0
names: Similarity
messages: Belongs to the PhyH family.

1136231:CORT 0C06430
gene id: 1136231:CORT_0C06430
uniprot id: H8X465
names: Similarity
messages: Belongs to the RRP15 family.

1136231:CORT 0E02610
gene id: 1136231:CORT_0E02610
uniprot id: H8X7R2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

1136231:CORT 0B04910
gene id: 1136231:CORT_0B04910
uniprot id: H8X1F9
names: Similarity
messages: Belongs to the pyridoxine kinase family.

1136231:CORT 0C04630
gene id: 1136231:CORT_0C04630
uniprot id: H8X2X7
names: Function
names: Subcellular Location Annotation
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus

1136231:CORT 0C04000
gene id: 1136231:CORT_0C04000
uniprot id: H8X3Y6
names: Similarity
messages: Belongs to the HMBS family.

1136231:CORT 0D03770
gene id: 1136231:CORT_0D03770
uniprot id: H8X5C3
names: Similarity
messages: Belongs to the phospholipase D family.

1136231:CORT 0A00820
gene id: 1136231:CORT_0A00820
uniprot id: H8WVK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0A12150
gene id: 1136231:CORT_0A12150
uniprot id: H8WYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0C05780
gene id: 1136231:CORT_0C05780
uniprot id: H8X391
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

1136231:CORT 0B05210
gene id: 1136231:CORT_0B05210
uniprot id: H8WZN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

1136231:CORT 0H01470
gene id: 1136231:CORT_0H01470
uniprot id: H8XB12
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D06650
gene id: 1136231:CORT_0D06650
uniprot id: H8X5P1
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1136231:CORT 0E02460
gene id: 1136231:CORT_0E02460
uniprot id: H8X7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

1136231:CORT 0C05640
gene id: 1136231:CORT_0C05640
uniprot id: H8X378
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1136231:CORT 0D04570
gene id: 1136231:CORT_0D04570
uniprot id: H8X649
names: Similarity
messages: Belongs to the MTFP1 family.

1136231:CORT 0F00970
gene id: 1136231:CORT_0F00970
uniprot id: H8X927
names: Similarity
messages: Belongs to the peptidase C12 family.

1136231:CORT 0F00570
gene id: 1136231:CORT_0F00570
uniprot id: H8X8Y8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D00930
gene id: 1136231:CORT_0D00930
uniprot id: H8X4J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

1136231:CORT 0B05100
gene id: 1136231:CORT_0B05100
uniprot id: H8WZM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1136231:CORT 0D02180
gene id: 1136231:CORT_0D02180
uniprot id: H8X4X3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B10030
gene id: 1136231:CORT_0B10030
uniprot id: H8X1Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

1136231:CORT 0B02120
gene id: 1136231:CORT_0B02120
uniprot id: H8X0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Membrane

1136231:CORT 0B07050
gene id: 1136231:CORT_0B07050
uniprot id: H8X1K7
names: Similarity
messages: Belongs to the peptidase C19 family.

1136231:CORT 0H01150
gene id: 1136231:CORT_0H01150
uniprot id: H8XAY3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D05140
gene id: 1136231:CORT_0D05140
uniprot id: H8X6A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

1136231:CORT 0A08010
gene id: 1136231:CORT_0A08010
uniprot id: H8WX47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

1136231:CORT 0H01630
gene id: 1136231:CORT_0H01630
uniprot id: H8XB28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1136231:CORT 0E06220
gene id: 1136231:CORT_0E06220
uniprot id: H8X8A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

1136231:CORT 0C04290
gene id: 1136231:CORT_0C04290
uniprot id: H8X414
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

1136231:CORT 0C04940
gene id: 1136231:CORT_0C04940
uniprot id: H8X308
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0G03860
gene id: 1136231:CORT_0G03860
uniprot id: H8XA86
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

1136231:CORT 0B05710
gene id: 1136231:CORT_0B05710
uniprot id: H8WZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

1136231:CORT 0C00760
gene id: 1136231:CORT_0C00760
uniprot id: H8X3I0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1136231:CORT 0D04770
gene id: 1136231:CORT_0D04770
uniprot id: H8X669
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0H01840
gene id: 1136231:CORT_0H01840
uniprot id: H8XB48
names: Similarity
messages: Belongs to the WD repeat coronin family.

1136231:CORT 0E01760
gene id: 1136231:CORT_0E01760
uniprot id: H8X7H9
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1136231:CORT 0G03320
gene id: 1136231:CORT_0G03320
uniprot id: H8XA32
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0C06580
gene id: 1136231:CORT_0C06580
uniprot id: H8X479
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1136231:CORT 0E03630
gene id: 1136231:CORT_0E03630
uniprot id: H8X723
names: Similarity
messages: Belongs to the XPC family.

1136231:CORT 0A01300
gene id: 1136231:CORT_0A01300
uniprot id: H8WVP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

1136231:CORT 0B06600
gene id: 1136231:CORT_0B06600
uniprot id: H8X023
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0F03970
gene id: 1136231:CORT_0F03970
uniprot id: H8X9F5
names: Similarity
messages: Belongs to the SH3BGR family.

1136231:CORT 0F02970
gene id: 1136231:CORT_0F02970
uniprot id: H8X8P6
names: Similarity
messages: Belongs to the CBP3 family.

1136231:CORT 0G03790
gene id: 1136231:CORT_0G03790
uniprot id: H8XA79
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1136231:CORT 0A01340
gene id: 1136231:CORT_0A01340
uniprot id: H8WVQ2
names: Similarity
messages: Belongs to the MT-A70-like family.

1136231:CORT 0D00110
gene id: 1136231:CORT_0D00110
uniprot id: H8X5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0D03080
gene id: 1136231:CORT_0D03080
uniprot id: H8X560
names: Similarity
messages: Belongs to the PDCD5 family.

1136231:CORT 0C02800
gene id: 1136231:CORT_0C02800
uniprot id: H8X3L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG9 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

1136231:CORT 0E06060
gene id: 1136231:CORT_0E06060
uniprot id: H8X889
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.

1136231:CORT 0A06020
gene id: 1136231:CORT_0A06020
uniprot id: H8WY42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B10770
gene id: 1136231:CORT_0B10770
uniprot id: H8X257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

1136231:CORT 0D00530
gene id: 1136231:CORT_0D00530
uniprot id: H8X4F9
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

1136231:CORT 0G00880
gene id: 1136231:CORT_0G00880
uniprot id: H8X9V9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

1136231:CORT 0E03450
gene id: 1136231:CORT_0E03450
uniprot id: H8X705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

1136231:CORT 0B02340
gene id: 1136231:CORT_0B02340
uniprot id: H8X0R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1136231:CORT 0A02150
gene id: 1136231:CORT_0A02150
uniprot id: H8WVY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

1136231:CORT 0C06750
gene id: 1136231:CORT_0C06750
uniprot id: H8X495
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1136231:CORT 0E00360
gene id: 1136231:CORT_0E00360
uniprot id: H8X6L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0A03110
gene id: 1136231:CORT_0A03110
uniprot id: H8WW76
names: Function
names: Subunit
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

1136231:CORT 0E00270
gene id: 1136231:CORT_0E00270
uniprot id: H8X6K7
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B04140
gene id: 1136231:CORT_0B04140
uniprot id: H8X181
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0B07140
gene id: 1136231:CORT_0B07140
uniprot id: H8X1L6
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1136231:CORT 0D04820
gene id: 1136231:CORT_0D04820
uniprot id: H8X674
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

1136231:CORT 0F02450
gene id: 1136231:CORT_0F02450
uniprot id: H8X8J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

1136231:CORT 0C05830
gene id: 1136231:CORT_0C05830
uniprot id: H8X396
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

1136231:CORT 0C02520
gene id: 1136231:CORT_0C02520
uniprot id: H8X2T0
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0D05090
gene id: 1136231:CORT_0D05090
uniprot id: H8X6A1
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1136231:CORT 0F04040
gene id: 1136231:CORT_0F04040
uniprot id: H8X9G2
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1136231:CORT 0F01130
gene id: 1136231:CORT_0F01130
uniprot id: H8X942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0C03490
gene id: 1136231:CORT_0C03490
uniprot id: H8X3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0C03890
gene id: 1136231:CORT_0C03890
uniprot id: H8X3X5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1136231:CORT 0C00990
gene id: 1136231:CORT_0C00990
uniprot id: H8X3K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Nucleus

1136231:CORT 0B09940
gene id: 1136231:CORT_0B09940
uniprot id: H8X0I6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: GTPase-activating protein for the ADP ribosylation factor family.

1136231:CORT 0B00700
gene id: 1136231:CORT_0B00700
uniprot id: H8WZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

1136231:CORT 0B04450
gene id: 1136231:CORT_0B04450
uniprot id: H8X1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Membrane
messages: nuclear pore complex

1136231:CORT 0H00480
gene id: 1136231:CORT_0H00480
uniprot id: H8XBH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM12 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

1136231:CORT 0H02740
gene id: 1136231:CORT_0H02740
uniprot id: H8XBD5
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

1136231:CORT 0F02070
gene id: 1136231:CORT_0F02070
uniprot id: H8X8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1136231:CORT 0C00460
gene id: 1136231:CORT_0C00460
uniprot id: H8X3F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1136231:CORT 0C00970
gene id: 1136231:CORT_0C00970
uniprot id: H8X3K1
names: Similarity
messages: Belongs to the XPC family.

1136231:CORT 0B02290
gene id: 1136231:CORT_0B02290
uniprot id: H8X0Q7
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0A04130
gene id: 1136231:CORT_0A04130
uniprot id: H8WWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

1136231:CORT 0D03340
gene id: 1136231:CORT_0D03340
uniprot id: H8X584
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

1136231:CORT 0F02780
gene id: 1136231:CORT_0F02780
uniprot id: H8X8M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

1136231:CORT 0G01140
gene id: 1136231:CORT_0G01140
uniprot id: H8XAF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1136231:CORT 0E04730
gene id: 1136231:CORT_0E04730
uniprot id: H8X7C9
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

1136231:CORT 0H02720
gene id: 1136231:CORT_0H02720
uniprot id: H8XBD3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A11210
gene id: 1136231:CORT_0A11210
uniprot id: H8WXK0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1136231:CORT 0A05300
gene id: 1136231:CORT_0A05300
uniprot id: H8WXX1
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

1136231:CORT 0G03720
gene id: 1136231:CORT_0G03720
uniprot id: H8XA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

1136231:CORT 0B08220
gene id: 1136231:CORT_0B08220
uniprot id: H8X1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1136231:CORT 0A07400
gene id: 1136231:CORT_0A07400
uniprot id: H8WWY5
names: Similarity
messages: Belongs to the CCS1 family.

1136231:CORT 0F01150
gene id: 1136231:CORT_0F01150
uniprot id: H8X944
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1136231:CORT 0B11420
gene id: 1136231:CORT_0B11420
uniprot id: H8X2B9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

1136231:CORT 0A06550
gene id: 1136231:CORT_0A06550
uniprot id: H8WWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

1136231:CORT 0C04220
gene id: 1136231:CORT_0C04220
uniprot id: H8X407
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALS family.
messages: Cell membrane
messages: Membrane
messages: cell wall

1136231:CORT 0E02700
gene id: 1136231:CORT_0E02700
uniprot id: H8X7S1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1136231:CORT 0C04490
gene id: 1136231:CORT_0C04490
uniprot id: H8X2W2
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1136231:CORT 0A07310
gene id: 1136231:CORT_0A07310
uniprot id: H8WWX6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A08450
gene id: 1136231:CORT_0A08450
uniprot id: H8WYB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

1136231:CORT 0B02640
gene id: 1136231:CORT_0B02640
uniprot id: H8X0U0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A09970
gene id: 1136231:CORT_0A09970
uniprot id: H8WX77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

1136231:CORT 0D05950
gene id: 1136231:CORT_0D05950
uniprot id: H8X5H7
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

1136231:CORT 0B09360
gene id: 1136231:CORT_0B09360
uniprot id: H8X0C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0A09415
gene id: 1136231:CORT_0A09415
uniprot id: H8WYL1
names: Similarity
messages: Belongs to the sulfiredoxin family.

1136231:CORT 0A02130
gene id: 1136231:CORT_0A02130
uniprot id: H8WVY0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

1136231:CORT 0B03290
gene id: 1136231:CORT_0B03290
uniprot id: H8X0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0B05370
gene id: 1136231:CORT_0B05370
uniprot id: H8WZQ0
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

1136231:CORT 0D06620
gene id: 1136231:CORT_0D06620
uniprot id: H8X5N8
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1136231:CORT 0A04170
gene id: 1136231:CORT_0A04170
uniprot id: H8WWI1
names: Similarity
messages: Belongs to the profilin family.

1136231:CORT 0B08390
gene id: 1136231:CORT_0B08390
uniprot id: H8X033
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

1136231:CORT 0D02840
gene id: 1136231:CORT_0D02840
uniprot id: H8X536
names: Similarity
messages: Belongs to the SELO family.

1136231:CORT 0B00330
gene id: 1136231:CORT_0B00330
uniprot id: H8WZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0A10260
gene id: 1136231:CORT_0A10260
uniprot id: H8WXA6
names: Function
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.

1136231:CORT 0A05320
gene id: 1136231:CORT_0A05320
uniprot id: H8WXX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1136231:CORT 0B06330
gene id: 1136231:CORT_0B06330
uniprot id: H8WZZ7
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0B05120
gene id: 1136231:CORT_0B05120
uniprot id: H8WZM5
names: Similarity
messages: Belongs to the AAA ATPase family. PCH2 subfamily.

1136231:CORT 0F03740
gene id: 1136231:CORT_0F03740
uniprot id: H8X9D1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E06050
gene id: 1136231:CORT_0E06050
uniprot id: H8X888
names: Function
names: Similarity
messages: Belongs to the CCM1 family.
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome.

1136231:CORT 0B09950
gene id: 1136231:CORT_0B09950
uniprot id: H8X0I7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E03520
gene id: 1136231:CORT_0E03520
uniprot id: H8X712
names: Similarity
messages: Belongs to the yippee family.

1136231:CORT 0C06680
gene id: 1136231:CORT_0C06680
uniprot id: H8X488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

1136231:CORT 0A11670
gene id: 1136231:CORT_0A11670
uniprot id: H8WYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

1136231:CORT 0E05870
gene id: 1136231:CORT_0E05870
uniprot id: H8X871
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

1136231:CORT 0D06480
gene id: 1136231:CORT_0D06480
uniprot id: H8X5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1136231:CORT 0C07010
gene id: 1136231:CORT_0C07010
uniprot id: H8X4C0
names: Similarity
messages: Belongs to the transglutaminase-like superfamily. PNGase family.

1136231:CORT 0A01110
gene id: 1136231:CORT_0A01110
uniprot id: H8WVN0
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1136231:CORT 0C06920
gene id: 1136231:CORT_0C06920
uniprot id: H8X4B2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B05750
gene id: 1136231:CORT_0B05750
uniprot id: H8WZT9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1136231:CORT 0G03430
gene id: 1136231:CORT_0G03430
uniprot id: H8XA42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1136231:CORT 0B05990
gene id: 1136231:CORT_0B05990
uniprot id: H8WZW3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1136231:CORT 0B01690
gene id: 1136231:CORT_0B01690
uniprot id: H8X0J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

1136231:CORT 0B05050
gene id: 1136231:CORT_0B05050
uniprot id: H8WZL8
names: Similarity
messages: Belongs to the CCDC124 family.

1136231:CORT 0E01510
gene id: 1136231:CORT_0E01510
uniprot id: H8X7F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0H00280
gene id: 1136231:CORT_0H00280
uniprot id: H8XBF8
names: Similarity
messages: Belongs to the peptidase S10 family.

1136231:CORT 0H00850
gene id: 1136231:CORT_0H00850
uniprot id: H8XBL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

1136231:CORT 0C01080
gene id: 1136231:CORT_0C01080
uniprot id: H8X2D8
names: Similarity
messages: Belongs to the FBPase class 1 family.

1136231:CORT 0B08670
gene id: 1136231:CORT_0B08670
uniprot id: H8X059
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1136231:CORT 0A07650
gene id: 1136231:CORT_0A07650
uniprot id: H8WX11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1136231:CORT 0G00430
gene id: 1136231:CORT_0G00430
uniprot id: H8X9R7
names: Similarity
messages: Belongs to the MEMO1 family.

1136231:CORT 0B03550
gene id: 1136231:CORT_0B03550
uniprot id: H8X124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

1136231:CORT 0B03600
gene id: 1136231:CORT_0B03600
uniprot id: H8X128
names: Similarity
messages: Belongs to the actin family.

1136231:CORT 0C00700
gene id: 1136231:CORT_0C00700
uniprot id: H8X3H5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D07070
gene id: 1136231:CORT_0D07070
uniprot id: H8X5T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

1136231:CORT 0A05360
gene id: 1136231:CORT_0A05360
uniprot id: H8WXX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

1136231:CORT 0B06870
gene id: 1136231:CORT_0B06870
uniprot id: H8X1J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

1136231:CORT 0B10410
gene id: 1136231:CORT_0B10410
uniprot id: H8X222
names: Similarity
messages: Belongs to the PIAS family.

1136231:CORT 0E01030
gene id: 1136231:CORT_0E01030
uniprot id: H8X6T1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0B06010
gene id: 1136231:CORT_0B06010
uniprot id: H8WZW5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1136231:CORT 0D06990
gene id: 1136231:CORT_0D06990
uniprot id: H8X5S4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0A09220
gene id: 1136231:CORT_0A09220
uniprot id: H8WYJ1
names: Similarity
messages: Belongs to the SHQ1 family.

1136231:CORT 0B11070
gene id: 1136231:CORT_0B11070
uniprot id: H8X284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

1136231:CORT 0F02600
gene id: 1136231:CORT_0F02600
uniprot id: H8X8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

1136231:CORT 0D02440
gene id: 1136231:CORT_0D02440
uniprot id: H8X4Z9
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.

1136231:CORT 0A02410
gene id: 1136231:CORT_0A02410
uniprot id: H8WW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

1136231:CORT 0D05500
gene id: 1136231:CORT_0D05500
uniprot id: H8X6E1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1136231:CORT 0G00870
gene id: 1136231:CORT_0G00870
uniprot id: H8X9V8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

1136231:CORT 0C05690
gene id: 1136231:CORT_0C05690
uniprot id: H8X383
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

1136231:CORT 0A13140
gene id: 1136231:CORT_0A13140
uniprot id: H8WXM4
names: Similarity
messages: Belongs to the VPS54 family.

1136231:CORT 0C00570
gene id: 1136231:CORT_0C00570
uniprot id: H8X3G2
names: Similarity
messages: Belongs to the cullin family.

1136231:CORT 0A07680
gene id: 1136231:CORT_0A07680
uniprot id: H8WX14
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

1136231:CORT 0F01350
gene id: 1136231:CORT_0F01350
uniprot id: H8X964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0C07080
gene id: 1136231:CORT_0C07080
uniprot id: H8X4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

1136231:CORT 0E02800
gene id: 1136231:CORT_0E02800
uniprot id: H8X7T1
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

1136231:CORT 0F01110
gene id: 1136231:CORT_0F01110
uniprot id: H8X940
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

1136231:CORT 0D06510
gene id: 1136231:CORT_0D06510
uniprot id: H8X5M8
names: Similarity
messages: Belongs to the MPI phosphatase family.

1136231:CORT 0A04310
gene id: 1136231:CORT_0A04310
uniprot id: H8WWJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1136231:CORT 0C05110
gene id: 1136231:CORT_0C05110
uniprot id: H8X325
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E01920
gene id: 1136231:CORT_0E01920
uniprot id: H8X7J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

1136231:CORT 0G01970
gene id: 1136231:CORT_0G01970
uniprot id: H8XAM9
names: Similarity
messages: Belongs to the PPP phosphatase family.

1136231:CORT 0C00480
gene id: 1136231:CORT_0C00480
uniprot id: H8X3F4
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

1136231:CORT 0A10770
gene id: 1136231:CORT_0A10770
uniprot id: H8WXF6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A09070
gene id: 1136231:CORT_0A09070
uniprot id: H8WYH6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1136231:CORT 0B08870
gene id: 1136231:CORT_0B08870
uniprot id: H8X079
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

1136231:CORT 0D03990
gene id: 1136231:CORT_0D03990
uniprot id: H8X5Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1136231:CORT 0D05260
gene id: 1136231:CORT_0D05260
uniprot id: H8X6B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0B08500
gene id: 1136231:CORT_0B08500
uniprot id: H8X042
names: Similarity
messages: Belongs to the peptidase M20A family.

1136231:CORT 0A12170
gene id: 1136231:CORT_0A12170
uniprot id: H8WYX0
names: Similarity
messages: Belongs to the peptidase C19 family.

1136231:CORT 0F04050
gene id: 1136231:CORT_0F04050
uniprot id: H8X9G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1136231:CORT 0C00940
gene id: 1136231:CORT_0C00940
uniprot id: H8X3J8
names: Similarity
messages: Belongs to the SPT2 family.

1136231:CORT 0A04120
gene id: 1136231:CORT_0A04120
uniprot id: H8WWH6
names: Function
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family.
messages: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.

1136231:CORT 0A13450
gene id: 1136231:CORT_0A13450
uniprot id: H8WXQ5
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated.

1136231:CORT 0D05780
gene id: 1136231:CORT_0D05780
uniprot id: H8X5G0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1136231:CORT 0A00160
gene id: 1136231:CORT_0A00160
uniprot id: H8WZ64
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1136231:CORT 0A02970
gene id: 1136231:CORT_0A02970
uniprot id: H8WW62
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

1136231:CORT 0G03840
gene id: 1136231:CORT_0G03840
uniprot id: H8XA84
names: Similarity
messages: Belongs to the peptidase S10 family.

1136231:CORT 0A00280
gene id: 1136231:CORT_0A00280
uniprot id: H8WVE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Preautophagosomal structure

1136231:CORT 0B05670
gene id: 1136231:CORT_0B05670
uniprot id: H8WZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-22 family.
messages: Involved in peroxisome biogenesis.
messages: Membrane
messages: Peroxisome membrane

1136231:CORT 0B02740
gene id: 1136231:CORT_0B02740
uniprot id: H8X0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Nucleus

1136231:CORT 0A06180
gene id: 1136231:CORT_0A06180
uniprot id: H8WY58
names: Similarity
messages: Belongs to the IFRD family.

1136231:CORT 0B08730
gene id: 1136231:CORT_0B08730
uniprot id: H8X065
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B09460
gene id: 1136231:CORT_0B09460
uniprot id: H8X0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0B09350
gene id: 1136231:CORT_0B09350
uniprot id: H8X0C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0A09450
gene id: 1136231:CORT_0A09450
uniprot id: H8WYL5
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

1136231:CORT 0A04040
gene id: 1136231:CORT_0A04040
uniprot id: H8WWG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

1136231:CORT 0A00420
gene id: 1136231:CORT_0A00420
uniprot id: H8WVG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC4 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

1136231:CORT 0G01800
gene id: 1136231:CORT_0G01800
uniprot id: H8XAL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0B08050
gene id: 1136231:CORT_0B08050
uniprot id: H8X1V4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136231:CORT 0B05800
gene id: 1136231:CORT_0B05800
uniprot id: H8WZU4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1136231:CORT 0B01820
gene id: 1136231:CORT_0B01820
uniprot id: H8X0L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

1136231:CORT 0B05850
gene id: 1136231:CORT_0B05850
uniprot id: H8WZU9
names: Similarity
messages: Belongs to the 4HPPD family.

1136231:CORT 0D06090
gene id: 1136231:CORT_0D06090
uniprot id: H8X5I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

1136231:CORT 0D02990
gene id: 1136231:CORT_0D02990
uniprot id: H8X551
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm
messages: Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.

1136231:CORT 0F01540
gene id: 1136231:CORT_0F01540
uniprot id: H8X982
names: Similarity
messages: Belongs to the EFG1 family.

1136231:CORT 0H00770
gene id: 1136231:CORT_0H00770
uniprot id: H8XBK6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F03500
gene id: 1136231:CORT_0F03500
uniprot id: H8X9A9
names: Function
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

1136231:CORT 0C03190
gene id: 1136231:CORT_0C03190
uniprot id: H8X3Q6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

1136231:CORT 0B03950
gene id: 1136231:CORT_0B03950
uniprot id: H8X163
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1136231:CORT 0G04190
gene id: 1136231:CORT_0G04190
uniprot id: H8XAB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1136231:CORT 0F04500
gene id: 1136231:CORT_0F04500
uniprot id: H8X9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1136231:CORT 0B05830
gene id: 1136231:CORT_0B05830
uniprot id: H8WZU7
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1136231:CORT 0A10710
gene id: 1136231:CORT_0A10710
uniprot id: H8WXF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1136231:CORT 0A06890
gene id: 1136231:CORT_0A06890
uniprot id: H8WWT4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A02710
gene id: 1136231:CORT_0A02710
uniprot id: H8WW37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1136231:CORT 0F01330
gene id: 1136231:CORT_0F01330
uniprot id: H8X962
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B07910
gene id: 1136231:CORT_0B07910
uniprot id: H8X1U1
names: Similarity
messages: Belongs to the PdxS/SNZ family.

1136231:CORT 0A00610
gene id: 1136231:CORT_0A00610
uniprot id: H8WVH9
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1136231:CORT 0H02610
gene id: 1136231:CORT_0H02610
uniprot id: H8XBC2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

1136231:CORT 0C03100
gene id: 1136231:CORT_0C03100
uniprot id: H8X3P8
names: Similarity
messages: Belongs to the SUN family.

1136231:CORT 0B06220
gene id: 1136231:CORT_0B06220
uniprot id: H8WZY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1136231:CORT 0B06820
gene id: 1136231:CORT_0B06820
uniprot id: H8X1I5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1136231:CORT 0C01840
gene id: 1136231:CORT_0C01840
uniprot id: H8X2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1136231:CORT 0B10450
gene id: 1136231:CORT_0B10450
uniprot id: H8X226
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

1136231:CORT 0G03680
gene id: 1136231:CORT_0G03680
uniprot id: H8XA67
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

1136231:CORT 0B06480
gene id: 1136231:CORT_0B06480
uniprot id: H8X012
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

1136231:CORT 0G01610
gene id: 1136231:CORT_0G01610
uniprot id: H8XAJ8
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1136231:CORT 0B06980
gene id: 1136231:CORT_0B06980
uniprot id: H8X1K0
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

1136231:CORT 0E05490
gene id: 1136231:CORT_0E05490
uniprot id: H8X835
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

1136231:CORT 0H00950
gene id: 1136231:CORT_0H00950
uniprot id: H8XAW3
names: Subcellular Location Annotation
messages: cytosol

1136231:CORT 0B11270
gene id: 1136231:CORT_0B11270
uniprot id: H8X2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

1136231:CORT 0A01210
gene id: 1136231:CORT_0A01210
uniprot id: H8WVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

1136231:CORT 0C04980
gene id: 1136231:CORT_0C04980
uniprot id: H8X312
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

1136231:CORT 0A10190
gene id: 1136231:CORT_0A10190
uniprot id: H8WX99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAC3 family.
messages: Nucleus envelope

1136231:CORT 0G02230
gene id: 1136231:CORT_0G02230
uniprot id: H8XAQ3
names: Similarity
messages: Belongs to the NifU family.

1136231:CORT 0A01760
gene id: 1136231:CORT_0A01760
uniprot id: H8WVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0C05910
gene id: 1136231:CORT_0C05910
uniprot id: H8X3A4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

1136231:CORT 0B02240
gene id: 1136231:CORT_0B02240
uniprot id: H8X0Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0B02350
gene id: 1136231:CORT_0B02350
uniprot id: H8X0R2
names: Similarity
messages: Belongs to the SUI1 family.

1136231:CORT 0F00840
gene id: 1136231:CORT_0F00840
uniprot id: H8X914
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F03530
gene id: 1136231:CORT_0F03530
uniprot id: H8X9B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0E00500
gene id: 1136231:CORT_0E00500
uniprot id: H8X6M9
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1136231:CORT 0B01230
gene id: 1136231:CORT_0B01230
uniprot id: H8WZH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

1136231:CORT 0D06110
gene id: 1136231:CORT_0D06110
uniprot id: H8X5J1
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

1136231:CORT 0F02740
gene id: 1136231:CORT_0F02740
uniprot id: H8X8M3
names: Similarity
messages: Belongs to the lysophospholipase family.

1136231:CORT 0A08200
gene id: 1136231:CORT_0A08200
uniprot id: H8WY90
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

1136231:CORT 0G01950
gene id: 1136231:CORT_0G01950
uniprot id: H8XAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B10660
gene id: 1136231:CORT_0B10660
uniprot id: H8X246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

1136231:CORT 0B08750
gene id: 1136231:CORT_0B08750
uniprot id: H8X067
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

1136231:CORT 0A02750
gene id: 1136231:CORT_0A02750
uniprot id: H8WW41
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B04510
gene id: 1136231:CORT_0B04510
uniprot id: H8X1B9
names: Similarity
messages: Belongs to the NPR2 family.

1136231:CORT 0B01540
gene id: 1136231:CORT_0B01540
uniprot id: H8WZK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

1136231:CORT 0C04370
gene id: 1136231:CORT_0C04370
uniprot id: H8X422
names: Similarity
messages: Belongs to the NAD kinase family.

1136231:CORT 0C01320
gene id: 1136231:CORT_0C01320
uniprot id: H8X2G2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F01100
gene id: 1136231:CORT_0F01100
uniprot id: H8X939
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0H01860
gene id: 1136231:CORT_0H01860
uniprot id: H8XB50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

1136231:CORT 0A09270
gene id: 1136231:CORT_0A09270
uniprot id: H8WYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD7 family.
messages: spindle pole

1136231:CORT 0F02950
gene id: 1136231:CORT_0F02950
uniprot id: H8X8P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

1136231:CORT 0F04550
gene id: 1136231:CORT_0F04550
uniprot id: H8X9L3
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1136231:CORT 0B04030
gene id: 1136231:CORT_0B04030
uniprot id: H8X170
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C06460
gene id: 1136231:CORT_0C06460
uniprot id: H8X468
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1136231:CORT 0A05690
gene id: 1136231:CORT_0A05690
uniprot id: H8WY09
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1136231:CORT 0A08570
gene id: 1136231:CORT_0A08570
uniprot id: H8WYC6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1136231:CORT 0C05200
gene id: 1136231:CORT_0C05200
uniprot id: H8X334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0D04680
gene id: 1136231:CORT_0D04680
uniprot id: H8X660
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

1136231:CORT 0E06070
gene id: 1136231:CORT_0E06070
uniprot id: H8X890
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

1136231:CORT 0A00680
gene id: 1136231:CORT_0A00680
uniprot id: H8WVI6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

1136231:CORT 0B08300
gene id: 1136231:CORT_0B08300
uniprot id: H8X1X9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1136231:CORT 0A13160
gene id: 1136231:CORT_0A13160
uniprot id: H8WXM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.
messages: Membrane
messages: Peroxisome membrane

1136231:CORT 0B06120
gene id: 1136231:CORT_0B06120
uniprot id: H8WZX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

1136231:CORT 0C04260
gene id: 1136231:CORT_0C04260
uniprot id: H8X411
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

1136231:CORT 0A12130
gene id: 1136231:CORT_0A12130
uniprot id: H8WYW6
names: Similarity
messages: Belongs to the BLOC1S2 family.

1136231:CORT 0B07280
gene id: 1136231:CORT_0B07280
uniprot id: H8X1N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.
messages: Belongs to the ATG17 family.
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

1136231:CORT 0G04360
gene id: 1136231:CORT_0G04360
uniprot id: H8XAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM54 family.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0B09990
gene id: 1136231:CORT_0B09990
uniprot id: H8X1Y2
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

1136231:CORT 0D02450
gene id: 1136231:CORT_0D02450
uniprot id: H8X500
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

1136231:CORT 0B10170
gene id: 1136231:CORT_0B10170
uniprot id: H8X200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 22 family.
messages: Nucleus

1136231:CORT 0D00520
gene id: 1136231:CORT_0D00520
uniprot id: H8X4F8
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0A00890
gene id: 1136231:CORT_0A00890
uniprot id: H8WVK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO4 family.
messages: Membrane

1136231:CORT 0B04050
gene id: 1136231:CORT_0B04050
uniprot id: H8X172
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1136231:CORT 0B01570
gene id: 1136231:CORT_0B01570
uniprot id: H8WZK8
names: Similarity
messages: Belongs to the Fmt family.

1136231:CORT 0C01340
gene id: 1136231:CORT_0C01340
uniprot id: H8X2G4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1136231:CORT 0A04910
gene id: 1136231:CORT_0A04910
uniprot id: H8WXT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.

1136231:CORT 0G01520
gene id: 1136231:CORT_0G01520
uniprot id: H8XAJ0
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1136231:CORT 0B03540
gene id: 1136231:CORT_0B03540
uniprot id: H8X123
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

1136231:CORT 0D07500
gene id: 1136231:CORT_0D07500
uniprot id: H8X6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0A12720
gene id: 1136231:CORT_0A12720
uniprot id: H8WZ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

1136231:CORT 0H02380
gene id: 1136231:CORT_0H02380
uniprot id: H8XB99
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G04220
gene id: 1136231:CORT_0G04220
uniprot id: H8XAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

1136231:CORT 0H01330
gene id: 1136231:CORT_0H01330
uniprot id: H8XAZ9
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0E05090
gene id: 1136231:CORT_0E05090
uniprot id: H8X7Z4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1136231:CORT 0G03980
gene id: 1136231:CORT_0G03980
uniprot id: H8XA98
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1136231:CORT 0B10780
gene id: 1136231:CORT_0B10780
uniprot id: H8X258
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

1136231:CORT 0G03760
gene id: 1136231:CORT_0G03760
uniprot id: H8XA75
names: Similarity
messages: Belongs to the amidase family.

1136231:CORT 0A10390
gene id: 1136231:CORT_0A10390
uniprot id: H8WXB9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1136231:CORT 0E06540
gene id: 1136231:CORT_0E06540
uniprot id: H8X7E1
names: Function
names: Similarity
messages: Belongs to the CTR86 family.
messages: Essential protein which may be involved in threonine biosynthesis.

1136231:CORT 0A06990
gene id: 1136231:CORT_0A06990
uniprot id: H8WWU4
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

1136231:CORT 0A01850
gene id: 1136231:CORT_0A01850
uniprot id: H8WVV2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

1136231:CORT 0A02940
gene id: 1136231:CORT_0A02940
uniprot id: H8WW59
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G01380
gene id: 1136231:CORT_0G01380
uniprot id: H8XAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1136231:CORT 0E05550
gene id: 1136231:CORT_0E05550
uniprot id: H8X841
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F01320
gene id: 1136231:CORT_0F01320
uniprot id: H8X961
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

1136231:CORT 0H01810
gene id: 1136231:CORT_0H01810
uniprot id: H8XB45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

1136231:CORT 0C04210
gene id: 1136231:CORT_0C04210
uniprot id: H8X406
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALS family.
messages: Cell membrane
messages: Membrane
messages: cell wall

1136231:CORT 0B03930
gene id: 1136231:CORT_0B03930
uniprot id: H8X161
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

1136231:CORT 0A01570
gene id: 1136231:CORT_0A01570
uniprot id: H8WVS5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G00720
gene id: 1136231:CORT_0G00720
uniprot id: H8X9U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1136231:CORT 0B06970
gene id: 1136231:CORT_0B06970
uniprot id: H8X1J9
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.

1136231:CORT 0A07890
gene id: 1136231:CORT_0A07890
uniprot id: H8WX35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: spindle

1136231:CORT 0H00980
gene id: 1136231:CORT_0H00980
uniprot id: H8XAW6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A05670
gene id: 1136231:CORT_0A05670
uniprot id: H8WY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

1136231:CORT 0E00840
gene id: 1136231:CORT_0E00840
uniprot id: H8X6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0H00500
gene id: 1136231:CORT_0H00500
uniprot id: H8XBH9
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

1136231:CORT 0A00440
gene id: 1136231:CORT_0A00440
uniprot id: H8WVG5
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1136231:CORT 0F01710
gene id: 1136231:CORT_0F01710
uniprot id: H8X999
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: The C2 domains have an essential, but non-catalytic function. They may facilitate interaction with PstB2 and are required for lipid transport function.

1136231:CORT 0A10360
gene id: 1136231:CORT_0A10360
uniprot id: H8WXB6
names: Similarity
messages: Belongs to the TACO1 family.

1136231:CORT 0F00420
gene id: 1136231:CORT_0F00420
uniprot id: H8X8X3
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

1136231:CORT 0E06250
gene id: 1136231:CORT_0E06250
uniprot id: H8X8A8
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1136231:CORT 0A03440
gene id: 1136231:CORT_0A03440
uniprot id: H8WWA8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1136231:CORT 0B03790
gene id: 1136231:CORT_0B03790
uniprot id: H8X147
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

1136231:CORT 0E03130
gene id: 1136231:CORT_0E03130
uniprot id: H8X6X4
names: Similarity
messages: Belongs to the PAT1 family.

1136231:CORT 0B09650
gene id: 1136231:CORT_0B09650
uniprot id: H8X0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1136231:CORT 0A00310
gene id: 1136231:CORT_0A00310
uniprot id: H8WVF2
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

1136231:CORT 0A06000
gene id: 1136231:CORT_0A06000
uniprot id: H8WY40
names: Cofactor
messages: Divalent metal ions. Mg(2+) is the most effective.

1136231:CORT 0B03830
gene id: 1136231:CORT_0B03830
uniprot id: H8X151
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0D04170
gene id: 1136231:CORT_0D04170
uniprot id: H8X609
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

1136231:CORT 0B08080
gene id: 1136231:CORT_0B08080
uniprot id: H8X1V7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1136231:CORT 0D00810
gene id: 1136231:CORT_0D00810
uniprot id: H8X4I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

1136231:CORT 0D00560
gene id: 1136231:CORT_0D00560
uniprot id: H8X4G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1136231:CORT 0A12670
gene id: 1136231:CORT_0A12670
uniprot id: H8WZ19
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

1136231:CORT 0C04540
gene id: 1136231:CORT_0C04540
uniprot id: H8X2W8
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

1136231:CORT 0A08320
gene id: 1136231:CORT_0A08320
uniprot id: H8WYA2
names: Similarity
messages: Belongs to the MAPRE family.

1136231:CORT 0D02780
gene id: 1136231:CORT_0D02780
uniprot id: H8X530
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1136231:CORT 0A09680
gene id: 1136231:CORT_0A09680
uniprot id: H8WYN8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F00830
gene id: 1136231:CORT_0F00830
uniprot id: H8X913
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1136231:CORT 0D03360
gene id: 1136231:CORT_0D03360
uniprot id: H8X586
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1136231:CORT 0D07210
gene id: 1136231:CORT_0D07210
uniprot id: H8X6E3
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

1136231:CORT 0B06990
gene id: 1136231:CORT_0B06990
uniprot id: H8X1K1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1136231:CORT 0A04600
gene id: 1136231:CORT_0A04600
uniprot id: H8WWM4
names: Similarity
messages: Belongs to the group II decarboxylase family.

1136231:CORT 0B03940
gene id: 1136231:CORT_0B03940
uniprot id: H8X162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

1136231:CORT 0G01390
gene id: 1136231:CORT_0G01390
uniprot id: H8XAH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1136231:CORT 0A08430
gene id: 1136231:CORT_0A08430
uniprot id: H8WYB2
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

1136231:CORT 0B10370
gene id: 1136231:CORT_0B10370
uniprot id: H8X218
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1136231:CORT 0C00840
gene id: 1136231:CORT_0C00840
uniprot id: H8X3I8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A11280
gene id: 1136231:CORT_0A11280
uniprot id: H8WXK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

1136231:CORT 0B00460
gene id: 1136231:CORT_0B00460
uniprot id: H8WZ99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1136231:CORT 0B08710
gene id: 1136231:CORT_0B08710
uniprot id: H8X063
names: Similarity
messages: Belongs to the peptidase S10 family.

1136231:CORT 0B10140
gene id: 1136231:CORT_0B10140
uniprot id: H8X1Z7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E02310
gene id: 1136231:CORT_0E02310
uniprot id: H8X7N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1136231:CORT 0A02280
gene id: 1136231:CORT_0A02280
uniprot id: H8WVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

1136231:CORT 0D03290
gene id: 1136231:CORT_0D03290
uniprot id: H8X579
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0C05060
gene id: 1136231:CORT_0C05060
uniprot id: H8X320
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B01100
gene id: 1136231:CORT_0B01100
uniprot id: H8WZG2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

1136231:CORT 0G02680
gene id: 1136231:CORT_0G02680
uniprot id: H8XAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

1136231:CORT 0E05530
gene id: 1136231:CORT_0E05530
uniprot id: H8X839
names: Similarity
messages: In the C-terminal section; belongs to the DHPS family.
messages: In the N-terminal section; belongs to the DHNA family.

1136231:CORT 0G03170
gene id: 1136231:CORT_0G03170
uniprot id: H8XA17
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136231:CORT 0B04570
gene id: 1136231:CORT_0B04570
uniprot id: H8X1C5
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0H02550
gene id: 1136231:CORT_0H02550
uniprot id: H8XBB6
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

1136231:CORT 0B11430
gene id: 1136231:CORT_0B11430
uniprot id: H8X2C0
names: Function
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0C05750
gene id: 1136231:CORT_0C05750
uniprot id: H8X389
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
messages: Nucleus

1136231:CORT 0G01180
gene id: 1136231:CORT_0G01180
uniprot id: H8XAF6
names: Similarity
messages: Belongs to the UPP synthase family.

1136231:CORT 0A07570
gene id: 1136231:CORT_0A07570
uniprot id: H8WX03
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

1136231:CORT 0E02910
gene id: 1136231:CORT_0E02910
uniprot id: H8X7U3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0C05210
gene id: 1136231:CORT_0C05210
uniprot id: H8X335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

1136231:CORT 0D06430
gene id: 1136231:CORT_0D06430
uniprot id: H8X5M1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B01090
gene id: 1136231:CORT_0B01090
uniprot id: H8WZG1
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0D03500
gene id: 1136231:CORT_0D03500
uniprot id: H8X599
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0A05960
gene id: 1136231:CORT_0A05960
uniprot id: H8WY36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.
messages: Membrane
messages: Peroxisome membrane

1136231:CORT 0C04170
gene id: 1136231:CORT_0C04170
uniprot id: H8X402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

1136231:CORT 0A04730
gene id: 1136231:CORT_0A04730
uniprot id: H8WXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0B08460
gene id: 1136231:CORT_0B08460
uniprot id: H8X039
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

1136231:CORT 0D01230
gene id: 1136231:CORT_0D01230
uniprot id: H8X4M9
names: Similarity
messages: Belongs to the peroxin-13 family.

1136231:CORT 0B10650
gene id: 1136231:CORT_0B10650
uniprot id: H8X245
names: Similarity
messages: Belongs to the TrpF family.

1136231:CORT 0C00280
gene id: 1136231:CORT_0C00280
uniprot id: H8X3D4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1136231:CORT 0A07740
gene id: 1136231:CORT_0A07740
uniprot id: H8WX20
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E03480
gene id: 1136231:CORT_0E03480
uniprot id: H8X708
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1136231:CORT 0F04710
gene id: 1136231:CORT_0F04710
uniprot id: H8X9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0A11610
gene id: 1136231:CORT_0A11610
uniprot id: H8WYR4
names: Similarity
messages: Belongs to the UFD1 family.

1136231:CORT 0D00500
gene id: 1136231:CORT_0D00500
uniprot id: H8X4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Nucleus

1136231:CORT 0A11060
gene id: 1136231:CORT_0A11060
uniprot id: H8WXI5
names: Similarity
messages: Belongs to the UPL family. TOM1/PTR1 subfamily.

1136231:CORT 0E04020
gene id: 1136231:CORT_0E04020
uniprot id: H8X761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

1136231:CORT 0D05740
gene id: 1136231:CORT_0D05740
uniprot id: H8X5F6
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

1136231:CORT 0G02010
gene id: 1136231:CORT_0G02010
uniprot id: H8XAN2
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

1136231:CORT 0G01060
gene id: 1136231:CORT_0G01060
uniprot id: H8X9X7
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D01380
gene id: 1136231:CORT_0D01380
uniprot id: H8X4P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1136231:CORT 0H02750
gene id: 1136231:CORT_0H02750
uniprot id: H8XBD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

1136231:CORT 0D02010
gene id: 1136231:CORT_0D02010
uniprot id: H8X4V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3.
messages: Nucleus

1136231:CORT 0B10460
gene id: 1136231:CORT_0B10460
uniprot id: H8X227
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0B03740
gene id: 1136231:CORT_0B03740
uniprot id: H8X142
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

1136231:CORT 0B11550
gene id: 1136231:CORT_0B11550
uniprot id: H8X2D2
names: Similarity
messages: Belongs to the TTC4 family.

1136231:CORT 0B08330
gene id: 1136231:CORT_0B08330
uniprot id: H8X027
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1136231:CORT 0A02370
gene id: 1136231:CORT_0A02370
uniprot id: H8WW04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

1136231:CORT 0G02390
gene id: 1136231:CORT_0G02390
uniprot id: H8XAR9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

1136231:CORT 0E05800
gene id: 1136231:CORT_0E05800
uniprot id: H8X865
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

1136231:CORT 0E00130
gene id: 1136231:CORT_0E00130
uniprot id: H8X6J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

1136231:CORT 0G00390
gene id: 1136231:CORT_0G00390
uniprot id: H8X9R3
names: Similarity
messages: Belongs to the peptidase C19 family.

1136231:CORT 0A05660
gene id: 1136231:CORT_0A05660
uniprot id: H8WY06
names: Similarity
messages: Belongs to the peptidase C12 family.

1136231:CORT 0A06960
gene id: 1136231:CORT_0A06960
uniprot id: H8WWU1
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

1136231:CORT 0D02250
gene id: 1136231:CORT_0D02250
uniprot id: H8X4Y0
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1136231:CORT 0B08800
gene id: 1136231:CORT_0B08800
uniprot id: H8X072
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

1136231:CORT 0D06950
gene id: 1136231:CORT_0D06950
uniprot id: H8X5S0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

1136231:CORT 0E04590
gene id: 1136231:CORT_0E04590
uniprot id: H8X7B6
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0D02150
gene id: 1136231:CORT_0D02150
uniprot id: H8X4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

1136231:CORT 0B08370
gene id: 1136231:CORT_0B08370
uniprot id: H8X031
names: Similarity
messages: Belongs to the cyclin family.

1136231:CORT 0C06480
gene id: 1136231:CORT_0C06480
uniprot id: H8X470
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0B02520
gene id: 1136231:CORT_0B02520
uniprot id: H8X0S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1136231:CORT 0F01080
gene id: 1136231:CORT_0F01080
uniprot id: H8X937
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

1136231:CORT 0A00950
gene id: 1136231:CORT_0A00950
uniprot id: H8WVL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

1136231:CORT 0F03750
gene id: 1136231:CORT_0F03750
uniprot id: H8X9D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Vesicle
messages: secretory vesicle

1136231:CORT 0A09920
gene id: 1136231:CORT_0A09920
uniprot id: H8WX72
names: Similarity
messages: Belongs to the peptidase M18 family.

1136231:CORT 0A12790
gene id: 1136231:CORT_0A12790
uniprot id: H8WZ31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

1136231:CORT 0A07240
gene id: 1136231:CORT_0A07240
uniprot id: H8WWW9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

1136231:CORT 0B10420
gene id: 1136231:CORT_0B10420
uniprot id: H8X223
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

1136231:CORT 0E03700
gene id: 1136231:CORT_0E03700
uniprot id: H8X730
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

1136231:CORT 0C04360
gene id: 1136231:CORT_0C04360
uniprot id: H8X421
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.

1136231:CORT 0A03680
gene id: 1136231:CORT_0A03680
uniprot id: H8WWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

1136231:CORT 0D07430
gene id: 1136231:CORT_0D07430
uniprot id: H8X6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool.
messages: Belongs to the complex I LYR family. MZM1 subfamily.
messages: Interacts with RIP1.
messages: Mitochondrion matrix

1136231:CORT 0C05470
gene id: 1136231:CORT_0C05470
uniprot id: H8X361
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0E02870
gene id: 1136231:CORT_0E02870
uniprot id: H8X7T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: Nucleus

1136231:CORT 0B06950
gene id: 1136231:CORT_0B06950
uniprot id: H8X1J8
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

1136231:CORT 0E03670
gene id: 1136231:CORT_0E03670
uniprot id: H8X727
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1136231:CORT 0B11450
gene id: 1136231:CORT_0B11450
uniprot id: H8X2C2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1136231:CORT 0D04670
gene id: 1136231:CORT_0D04670
uniprot id: H8X659
names: Similarity
messages: Belongs to the NOC2 family.

1136231:CORT 0A03700
gene id: 1136231:CORT_0A03700
uniprot id: H8WWD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

1136231:CORT 0C06400
gene id: 1136231:CORT_0C06400
uniprot id: H8X462
names: Similarity
messages: Belongs to the taffazin family.

1136231:CORT 0A03620
gene id: 1136231:CORT_0A03620
uniprot id: H8WWC6
names: Similarity
messages: Belongs to the FUN14 family.

1136231:CORT 0B05780
gene id: 1136231:CORT_0B05780
uniprot id: H8WZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1136231:CORT 0A06490
gene id: 1136231:CORT_0A06490
uniprot id: H8WWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

1136231:CORT 0F00310
gene id: 1136231:CORT_0F00310
uniprot id: H8X8W2
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity.

1136231:CORT 0C05410
gene id: 1136231:CORT_0C05410
uniprot id: H8X355
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm

1136231:CORT 0D01650
gene id: 1136231:CORT_0D01650
uniprot id: H8X4S1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

1136231:CORT 0A10380
gene id: 1136231:CORT_0A10380
uniprot id: H8WXB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0H02230
gene id: 1136231:CORT_0H02230
uniprot id: H8XB84
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1136231:CORT 0E02400
gene id: 1136231:CORT_0E02400
uniprot id: H8X7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1136231:CORT 0B07580
gene id: 1136231:CORT_0B07580
uniprot id: H8X1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1136231:CORT 0C06190
gene id: 1136231:CORT_0C06190
uniprot id: H8X440
names: Similarity
messages: Belongs to the WrbA family.

1136231:CORT 0B06380
gene id: 1136231:CORT_0B06380
uniprot id: H8X002
names: Similarity
messages: Belongs to the PPP phosphatase family.

1136231:CORT 0B06070
gene id: 1136231:CORT_0B06070
uniprot id: H8WZX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSM3 family.
messages: Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

1136231:CORT 0D03890
gene id: 1136231:CORT_0D03890
uniprot id: H8X5Y1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136231:CORT 0E02150
gene id: 1136231:CORT_0E02150
uniprot id: H8X7L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

1136231:CORT 0A06160
gene id: 1136231:CORT_0A06160
uniprot id: H8WY56
names: Cofactor
names: Similarity
messages: Belongs to the glutamate synthase family.
messages: Binds 1 [3Fe-4S] cluster.

1136231:CORT 0A08770
gene id: 1136231:CORT_0A08770
uniprot id: H8WYE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

1136231:CORT 0D04130
gene id: 1136231:CORT_0D04130
uniprot id: H8X605
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

1136231:CORT 0F03300
gene id: 1136231:CORT_0F03300
uniprot id: H8X8S9
names: Similarity
messages: Belongs to the FPG family.

1136231:CORT 0G02030
gene id: 1136231:CORT_0G02030
uniprot id: H8XAN4
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0F04600
gene id: 1136231:CORT_0F04600
uniprot id: H8X9L8
names: Similarity
messages: Belongs to the RAD52 family.

1136231:CORT 0C00790
gene id: 1136231:CORT_0C00790
uniprot id: H8X3I3
names: Similarity
messages: Belongs to the arginase family.

1136231:CORT 0C06740
gene id: 1136231:CORT_0C06740
uniprot id: H8X494
names: Similarity
messages: Belongs to the TCF25 family.

1136231:CORT 0A02650
gene id: 1136231:CORT_0A02650
uniprot id: H8WW32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0B02790
gene id: 1136231:CORT_0B02790
uniprot id: H8X0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1136231:CORT 0C01530
gene id: 1136231:CORT_0C01530
uniprot id: H8X2I3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C01690
gene id: 1136231:CORT_0C01690
uniprot id: H8X2J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

1136231:CORT 0E01560
gene id: 1136231:CORT_0E01560
uniprot id: H8X7G0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

1136231:CORT 0A05990
gene id: 1136231:CORT_0A05990
uniprot id: H8WY39
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

1136231:CORT 0C01950
gene id: 1136231:CORT_0C01950
uniprot id: H8X2M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

1136231:CORT 0E06040
gene id: 1136231:CORT_0E06040
uniprot id: H8X887
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0C06520
gene id: 1136231:CORT_0C06520
uniprot id: H8X473
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E00740
gene id: 1136231:CORT_0E00740
uniprot id: H8X6Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

1136231:CORT 0F01830
gene id: 1136231:CORT_0F01830
uniprot id: H8X8D5
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136231:CORT 0E00320
gene id: 1136231:CORT_0E00320
uniprot id: H8X6L2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F01070
gene id: 1136231:CORT_0F01070
uniprot id: H8X936
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E01160
gene id: 1136231:CORT_0E01160
uniprot id: H8X6U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0F03000
gene id: 1136231:CORT_0F03000
uniprot id: H8X8P9
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D03430
gene id: 1136231:CORT_0D03430
uniprot id: H8X592
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C00220
gene id: 1136231:CORT_0C00220
uniprot id: H8X3C8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

1136231:CORT 0B09180
gene id: 1136231:CORT_0B09180
uniprot id: H8X0B0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G01740
gene id: 1136231:CORT_0G01740
uniprot id: H8XAL0
names: Similarity
messages: Belongs to the peptidase S10 family.

1136231:CORT 0F03950
gene id: 1136231:CORT_0F03950
uniprot id: H8X9F3
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1136231:CORT 0E04170
gene id: 1136231:CORT_0E04170
uniprot id: H8X775
names: Similarity
messages: Belongs to the AAA ATPase family.

1136231:CORT 0B09710
gene id: 1136231:CORT_0B09710
uniprot id: H8X0G3
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B09060
gene id: 1136231:CORT_0B09060
uniprot id: H8X098
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

1136231:CORT 0A07040
gene id: 1136231:CORT_0A07040
uniprot id: H8WWU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

1136231:CORT 0B02900
gene id: 1136231:CORT_0B02900
uniprot id: H8X0W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

1136231:CORT 0A07490
gene id: 1136231:CORT_0A07490
uniprot id: H8WWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0E03140
gene id: 1136231:CORT_0E03140
uniprot id: H8X6X5
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1136231:CORT 0A11230
gene id: 1136231:CORT_0A11230
uniprot id: H8WXK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAN1 family.
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: Membrane
messages: actin patch

1136231:CORT 0A12180
gene id: 1136231:CORT_0A12180
uniprot id: H8WYX1
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

1136231:CORT 0E06400
gene id: 1136231:CORT_0E06400
uniprot id: H8X8C3
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0E05340
gene id: 1136231:CORT_0E05340
uniprot id: H8X820
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

1136231:CORT 0C04690
gene id: 1136231:CORT_0C04690
uniprot id: H8X2Y3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C04070
gene id: 1136231:CORT_0C04070
uniprot id: H8X3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

1136231:CORT 0F04150
gene id: 1136231:CORT_0F04150
uniprot id: H8X9H3
names: Function
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.
messages: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.

1136231:CORT 0C03620
gene id: 1136231:CORT_0C03620
uniprot id: H8X3U9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1136231:CORT 0A01640
gene id: 1136231:CORT_0A01640
uniprot id: H8WVT2
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

1136231:CORT 0B03560
gene id: 1136231:CORT_0B03560
uniprot id: H8X125
names: Similarity
messages: Belongs to the EIS1 family.

1136231:CORT 0D00870
gene id: 1136231:CORT_0D00870
uniprot id: H8X4J3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1136231:CORT 0A02830
gene id: 1136231:CORT_0A02830
uniprot id: H8WW49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1136231:CORT 0D06360
gene id: 1136231:CORT_0D06360
uniprot id: H8X5L4
names: Similarity
messages: Belongs to the VPS26 family.

1136231:CORT 0G04090
gene id: 1136231:CORT_0G04090
uniprot id: H8XAA9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1136231:CORT 0D07460
gene id: 1136231:CORT_0D07460
uniprot id: H8X6G8
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0C00580
gene id: 1136231:CORT_0C00580
uniprot id: H8X3G3
names: Function
messages: Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

1136231:CORT 0B02910
gene id: 1136231:CORT_0B02910
uniprot id: H8X0W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0D00210
gene id: 1136231:CORT_0D00210
uniprot id: H8X5V6
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0A06580
gene id: 1136231:CORT_0A06580
uniprot id: H8WWQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136231:CORT 0A08030
gene id: 1136231:CORT_0A08030
uniprot id: H8WX48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Mitochondrion inner membrane

1136231:CORT 0B01810
gene id: 1136231:CORT_0B01810
uniprot id: H8X0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

1136231:CORT 0B07840
gene id: 1136231:CORT_0B07840
uniprot id: H8X1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: mitochondrion nucleoid

1136231:CORT 0F00270
gene id: 1136231:CORT_0F00270
uniprot id: H8X8V8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1136231:CORT 0C05710
gene id: 1136231:CORT_0C05710
uniprot id: H8X385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0B02250
gene id: 1136231:CORT_0B02250
uniprot id: H8X0Q4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F01750
gene id: 1136231:CORT_0F01750
uniprot id: H8X8C7
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

1136231:CORT 0H00700
gene id: 1136231:CORT_0H00700
uniprot id: H8XBJ9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A09650
gene id: 1136231:CORT_0A09650
uniprot id: H8WYN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

1136231:CORT 0D00250
gene id: 1136231:CORT_0D00250
uniprot id: H8X5W0
names: Similarity
messages: Belongs to the biotin--protein ligase family.

1136231:CORT 0B08600
gene id: 1136231:CORT_0B08600
uniprot id: H8X052
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136231:CORT 0C05740
gene id: 1136231:CORT_0C05740
uniprot id: H8X388
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

1136231:CORT 0H01550
gene id: 1136231:CORT_0H01550
uniprot id: H8XB20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0E05930
gene id: 1136231:CORT_0E05930
uniprot id: H8X877
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0F03710
gene id: 1136231:CORT_0F03710
uniprot id: H8X9C8
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0C01330
gene id: 1136231:CORT_0C01330
uniprot id: H8X2G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1136231:CORT 0B09830
gene id: 1136231:CORT_0B09830
uniprot id: H8X0H5
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0H02170
gene id: 1136231:CORT_0H02170
uniprot id: H8XB78
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0B02470
gene id: 1136231:CORT_0B02470
uniprot id: H8X0S3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

1136231:CORT 0E05170
gene id: 1136231:CORT_0E05170
uniprot id: H8X803
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

1136231:CORT 0D07420
gene id: 1136231:CORT_0D07420
uniprot id: H8X6G4
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

1136231:CORT 0C03660
gene id: 1136231:CORT_0C03660
uniprot id: H8X3V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28A subfamily.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Vacuole membrane

1136231:CORT 0D03980
gene id: 1136231:CORT_0D03980
uniprot id: H8X5Z0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C02690
gene id: 1136231:CORT_0C02690
uniprot id: H8X2U7
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

1136231:CORT 0C00320
gene id: 1136231:CORT_0C00320
uniprot id: H8X3D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

1136231:CORT 0A05560
gene id: 1136231:CORT_0A05560
uniprot id: H8WXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1136231:CORT 0B01530
gene id: 1136231:CORT_0B01530
uniprot id: H8WZK4
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

1136231:CORT 0C07110
gene id: 1136231:CORT_0C07110
uniprot id: H8X4D0
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1136231:CORT 0E00780
gene id: 1136231:CORT_0E00780
uniprot id: H8X6Q6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1136231:CORT 0E01730
gene id: 1136231:CORT_0E01730
uniprot id: H8X7H6
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

1136231:CORT 0F03280
gene id: 1136231:CORT_0F03280
uniprot id: H8X8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1136231:CORT 0D02630
gene id: 1136231:CORT_0D02630
uniprot id: H8X515
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

1136231:CORT 0B10100
gene id: 1136231:CORT_0B10100
uniprot id: H8X1Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0D02030
gene id: 1136231:CORT_0D02030
uniprot id: H8X4V9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C00860
gene id: 1136231:CORT_0C00860
uniprot id: H8X3J0
names: Function
names: Subcellular Location Annotation
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion

1136231:CORT 0A13460
gene id: 1136231:CORT_0A13460
uniprot id: H8WXQ6
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

1136231:CORT 0F04620
gene id: 1136231:CORT_0F04620
uniprot id: H8X9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

1136231:CORT 0B11200
gene id: 1136231:CORT_0B11200
uniprot id: H8X297
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

1136231:CORT 0G01130
gene id: 1136231:CORT_0G01130
uniprot id: H8XAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Membrane

1136231:CORT 0B04670
gene id: 1136231:CORT_0B04670
uniprot id: H8X1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

1136231:CORT 0F03320
gene id: 1136231:CORT_0F03320
uniprot id: H8X8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1136231:CORT 0D06640
gene id: 1136231:CORT_0D06640
uniprot id: H8X5P0
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1136231:CORT 0A09110
gene id: 1136231:CORT_0A09110
uniprot id: H8WYI0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1136231:CORT 0C02310
gene id: 1136231:CORT_0C02310
uniprot id: H8X2R0
names: Similarity
messages: Belongs to the MAP65/ASE1 family.

1136231:CORT 0F04650
gene id: 1136231:CORT_0F04650
uniprot id: H8X9M4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

1136231:CORT 0B05950
gene id: 1136231:CORT_0B05950
uniprot id: H8WZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1136231:CORT 0B08190
gene id: 1136231:CORT_0B08190
uniprot id: H8X1W8
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

1136231:CORT 0G03440
gene id: 1136231:CORT_0G03440
uniprot id: H8XA43
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

1136231:CORT 0H00840
gene id: 1136231:CORT_0H00840
uniprot id: H8XBL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

1136231:CORT 0G03530
gene id: 1136231:CORT_0G03530
uniprot id: H8XA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

1136231:CORT 0E06270
gene id: 1136231:CORT_0E06270
uniprot id: H8X8B0
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1136231:CORT 0F00220
gene id: 1136231:CORT_0F00220
uniprot id: H8X8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1136231:CORT 0C00680
gene id: 1136231:CORT_0C00680
uniprot id: H8X3H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

1136231:CORT 0B02090
gene id: 1136231:CORT_0B02090
uniprot id: H8X0N8
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A11500
gene id: 1136231:CORT_0A11500
uniprot id: H8WYQ3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1136231:CORT 0A10170
gene id: 1136231:CORT_0A10170
uniprot id: H8WX97
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0A00640
gene id: 1136231:CORT_0A00640
uniprot id: H8WVI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

1136231:CORT 0B08960
gene id: 1136231:CORT_0B08960
uniprot id: H8X088
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

1136231:CORT 0B07520
gene id: 1136231:CORT_0B07520
uniprot id: H8X1Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1136231:CORT 0A04790
gene id: 1136231:CORT_0A04790
uniprot id: H8WXS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

1136231:CORT 0C03560
gene id: 1136231:CORT_0C03560
uniprot id: H8X3U3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1136231:CORT 0B05960
gene id: 1136231:CORT_0B05960
uniprot id: H8WZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

1136231:CORT 0A07290
gene id: 1136231:CORT_0A07290
uniprot id: H8WWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

1136231:CORT 0C01810
gene id: 1136231:CORT_0C01810
uniprot id: H8X2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

1136231:CORT 0C05360
gene id: 1136231:CORT_0C05360
uniprot id: H8X350
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1136231:CORT 0F03870
gene id: 1136231:CORT_0F03870
uniprot id: H8X9E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

1136231:CORT 0C06130
gene id: 1136231:CORT_0C06130
uniprot id: H8X434
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

1136231:CORT 0B07750
gene id: 1136231:CORT_0B07750
uniprot id: H8X1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1136231:CORT 0E03940
gene id: 1136231:CORT_0E03940
uniprot id: H8X753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0G01430
gene id: 1136231:CORT_0G01430
uniprot id: H8XAI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NMT1/THI5 family.
messages: Homodimer.
messages: Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.

1136231:CORT 0A09100
gene id: 1136231:CORT_0A09100
uniprot id: H8WYH9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1136231:CORT 0E00870
gene id: 1136231:CORT_0E00870
uniprot id: H8X6R5
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

1136231:CORT 0E05440
gene id: 1136231:CORT_0E05440
uniprot id: H8X830
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1136231:CORT 0B10710
gene id: 1136231:CORT_0B10710
uniprot id: H8X251
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

1136231:CORT 0D04450
gene id: 1136231:CORT_0D04450
uniprot id: H8X637
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1136231:CORT 0B04390
gene id: 1136231:CORT_0B04390
uniprot id: H8X1A6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F01480
gene id: 1136231:CORT_0F01480
uniprot id: H8X976
names: Similarity
messages: Belongs to the NDK family.

1136231:CORT 0B07220
gene id: 1136231:CORT_0B07220
uniprot id: H8X1M4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1136231:CORT 0C00780
gene id: 1136231:CORT_0C00780
uniprot id: H8X3I2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B03810
gene id: 1136231:CORT_0B03810
uniprot id: H8X149
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0A07700
gene id: 1136231:CORT_0A07700
uniprot id: H8WX16
names: Similarity
messages: Belongs to the SurE nucleotidase family.

1136231:CORT 0B08120
gene id: 1136231:CORT_0B08120
uniprot id: H8X1W1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A07370
gene id: 1136231:CORT_0A07370
uniprot id: H8WWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0A06710
gene id: 1136231:CORT_0A06710
uniprot id: H8WWR6
names: Similarity
messages: Belongs to the actin family.

1136231:CORT 0D07520
gene id: 1136231:CORT_0D07520
uniprot id: H8X6H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

1136231:CORT 0A04260
gene id: 1136231:CORT_0A04260
uniprot id: H8WWJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

1136231:CORT 0G03600
gene id: 1136231:CORT_0G03600
uniprot id: H8XA59
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1136231:CORT 0G02900
gene id: 1136231:CORT_0G02900
uniprot id: H8X9Z1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F00140
gene id: 1136231:CORT_0F00140
uniprot id: H8X8U6
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

1136231:CORT 0E03710
gene id: 1136231:CORT_0E03710
uniprot id: H8X731
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

1136231:CORT 0B04970
gene id: 1136231:CORT_0B04970
uniprot id: H8X1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

1136231:CORT 0B07270
gene id: 1136231:CORT_0B07270
uniprot id: H8X1M9
names: Similarity
messages: Belongs to the CDC73 family.

1136231:CORT 0B11370
gene id: 1136231:CORT_0B11370
uniprot id: H8X2B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

1136231:CORT 0C02850
gene id: 1136231:CORT_0C02850
uniprot id: H8X3M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0C02220
gene id: 1136231:CORT_0C02220
uniprot id: H8X2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

1136231:CORT 0B06760
gene id: 1136231:CORT_0B06760
uniprot id: H8X1H9
names: Similarity
messages: Belongs to the sulfatase family.

1136231:CORT 0A05770
gene id: 1136231:CORT_0A05770
uniprot id: H8WY17
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G00920
gene id: 1136231:CORT_0G00920
uniprot id: H8X9W3
names: Similarity
messages: Belongs to the RNR ribonuclease family.

1136231:CORT 0A09790
gene id: 1136231:CORT_0A09790
uniprot id: H8WX59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0A12810
gene id: 1136231:CORT_0A12810
uniprot id: H8WZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1136231:CORT 0A07550
gene id: 1136231:CORT_0A07550
uniprot id: H8WX01
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1136231:CORT 0A04670
gene id: 1136231:CORT_0A04670
uniprot id: H8WWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0B11290
gene id: 1136231:CORT_0B11290
uniprot id: H8X2A6
names: Similarity
messages: Belongs to the cyclin family.

1136231:CORT 0B05860
gene id: 1136231:CORT_0B05860
uniprot id: H8WZV0
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

1136231:CORT 0B05700
gene id: 1136231:CORT_0B05700
uniprot id: H8WZT4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0D07630
gene id: 1136231:CORT_0D07630
uniprot id: H8X6I5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1136231:CORT 0B05010
gene id: 1136231:CORT_0B05010
uniprot id: H8WZL4
names: Similarity
messages: Belongs to the cullin family.

1136231:CORT 0D02220
gene id: 1136231:CORT_0D02220
uniprot id: H8X4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

1136231:CORT 0D03560
gene id: 1136231:CORT_0D03560
uniprot id: H8X5A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136231:CORT 0E01430
gene id: 1136231:CORT_0E01430
uniprot id: H8X7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1136231:CORT 0D02100
gene id: 1136231:CORT_0D02100
uniprot id: H8X4W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

1136231:CORT 0C02110
gene id: 1136231:CORT_0C02110
uniprot id: H8X2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

1136231:CORT 0A06220
gene id: 1136231:CORT_0A06220
uniprot id: H8WY62
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E00850
gene id: 1136231:CORT_0E00850
uniprot id: H8X6R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1136231:CORT 0D00220
gene id: 1136231:CORT_0D00220
uniprot id: H8X5V7
names: Similarity
messages: Belongs to the LTV1 family.

1136231:CORT 0B05570
gene id: 1136231:CORT_0B05570
uniprot id: H8WZS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

1136231:CORT 0G03370
gene id: 1136231:CORT_0G03370
uniprot id: H8XA36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

1136231:CORT 0A10050
gene id: 1136231:CORT_0A10050
uniprot id: H8WX85
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E06320
gene id: 1136231:CORT_0E06320
uniprot id: H8X8B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Nucleus matrix
messages: cytoskeleton

1136231:CORT 0B07810
gene id: 1136231:CORT_0B07810
uniprot id: H8X1T1
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1136231:CORT 0D04200
gene id: 1136231:CORT_0D04200
uniprot id: H8X612
names: Similarity
messages: Belongs to the TMEM14 family.

1136231:CORT 0D06070
gene id: 1136231:CORT_0D06070
uniprot id: H8X5I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

1136231:CORT 0A01290
gene id: 1136231:CORT_0A01290
uniprot id: H8WVP7
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1136231:CORT 0A00340
gene id: 1136231:CORT_0A00340
uniprot id: H8WVF4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1136231:CORT 0B09420
gene id: 1136231:CORT_0B09420
uniprot id: H8X0D4
names: Similarity
messages: Belongs to the MYG1 family.

1136231:CORT 0D02570
gene id: 1136231:CORT_0D02570
uniprot id: H8X510
names: Similarity
messages: Belongs to the MCM family.

1136231:CORT 0B04260
gene id: 1136231:CORT_0B04260
uniprot id: H8X193
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.

1136231:CORT 0A12660
gene id: 1136231:CORT_0A12660
uniprot id: H8WZ18
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

1136231:CORT 0E05890
gene id: 1136231:CORT_0E05890
uniprot id: H8X873
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

1136231:CORT 0B08780
gene id: 1136231:CORT_0B08780
uniprot id: H8X070
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1136231:CORT 0A02050
gene id: 1136231:CORT_0A02050
uniprot id: H8WVX2
names: Similarity
names: Subunit
messages: Belongs to the EXO5 family.
messages: Monomer.

1136231:CORT 0B07570
gene id: 1136231:CORT_0B07570
uniprot id: H8X1Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0C05310
gene id: 1136231:CORT_0C05310
uniprot id: H8X345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0C01630
gene id: 1136231:CORT_0C01630
uniprot id: H8X2J3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1136231:CORT 0H02430
gene id: 1136231:CORT_0H02430
uniprot id: H8XBA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0D03700
gene id: 1136231:CORT_0D03700
uniprot id: H8X5B7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D01960
gene id: 1136231:CORT_0D01960
uniprot id: H8X4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1136231:CORT 0C05850
gene id: 1136231:CORT_0C05850
uniprot id: H8X398
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1136231:CORT 0B11160
gene id: 1136231:CORT_0B11160
uniprot id: H8X293
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

1136231:CORT 0C02600
gene id: 1136231:CORT_0C02600
uniprot id: H8X2T8
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1136231:CORT 0B10220
gene id: 1136231:CORT_0B10220
uniprot id: H8X205
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136231:CORT 0B05770
gene id: 1136231:CORT_0B05770
uniprot id: H8WZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1136231:CORT 0E04840
gene id: 1136231:CORT_0E04840
uniprot id: H8X7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytoskeleton

1136231:CORT 0D07650
gene id: 1136231:CORT_0D07650
uniprot id: H8X6I7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136231:CORT 0H01230
gene id: 1136231:CORT_0H01230
uniprot id: H8XAZ1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.

1136231:CORT 0F03080
gene id: 1136231:CORT_0F03080
uniprot id: H8X8Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

1136231:CORT 0F03620
gene id: 1136231:CORT_0F03620
uniprot id: H8X9B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

1136231:CORT 0A06820
gene id: 1136231:CORT_0A06820
uniprot id: H8WWS7
names: Similarity
messages: Belongs to the ATG101 family.

1136231:CORT 0E01820
gene id: 1136231:CORT_0E01820
uniprot id: H8X7I5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0A03290
gene id: 1136231:CORT_0A03290
uniprot id: H8WW93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

1136231:CORT 0H00360
gene id: 1136231:CORT_0H00360
uniprot id: H8XBG6
names: Similarity
messages: Belongs to the RRP12 family.

1136231:CORT 0C02100
gene id: 1136231:CORT_0C02100
uniprot id: H8X2N9
names: Similarity
messages: Belongs to the cyclin family.

1136231:CORT 0B05980
gene id: 1136231:CORT_0B05980
uniprot id: H8WZW2
names: Similarity
messages: Belongs to the HUS1 family.

1136231:CORT 0F02090
gene id: 1136231:CORT_0F02090
uniprot id: H8X8F9
names: Function
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0C05730
gene id: 1136231:CORT_0C05730
uniprot id: H8X387
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E06360
gene id: 1136231:CORT_0E06360
uniprot id: H8X8B9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1136231:CORT 0B10740
gene id: 1136231:CORT_0B10740
uniprot id: H8X254
names: Similarity
messages: Belongs to the COG2 family.

1136231:CORT 0A05000
gene id: 1136231:CORT_0A05000
uniprot id: H8WXU1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B09810
gene id: 1136231:CORT_0B09810
uniprot id: H8X0H3
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

1136231:CORT 0D05480
gene id: 1136231:CORT_0D05480
uniprot id: H8X6D9
names: Similarity
messages: Belongs to the PP2C family.

1136231:CORT 0D04520
gene id: 1136231:CORT_0D04520
uniprot id: H8X644
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GMC oxidoreductase family.
messages: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.
messages: Peroxisome matrix

1136231:CORT 0C06440
gene id: 1136231:CORT_0C06440
uniprot id: H8X466
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D06560
gene id: 1136231:CORT_0D06560
uniprot id: H8X5N2
names: Similarity
messages: Belongs to the diacylglycerol acyltransferase family.

1136231:CORT 0F00370
gene id: 1136231:CORT_0F00370
uniprot id: H8X8W8
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

1136231:CORT 0B06000
gene id: 1136231:CORT_0B06000
uniprot id: H8WZW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

1136231:CORT 0D02300
gene id: 1136231:CORT_0D02300
uniprot id: H8X4Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

1136231:CORT 0D02200
gene id: 1136231:CORT_0D02200
uniprot id: H8X4X5
names: Similarity
messages: Belongs to the CAP family.

1136231:CORT 0A11480
gene id: 1136231:CORT_0A11480
uniprot id: H8WYQ1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1136231:CORT 0F03650
gene id: 1136231:CORT_0F03650
uniprot id: H8X9C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.

1136231:CORT 0C01960
gene id: 1136231:CORT_0C01960
uniprot id: H8X2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

1136231:CORT 0G03150
gene id: 1136231:CORT_0G03150
uniprot id: H8XA15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

1136231:CORT 0E00410
gene id: 1136231:CORT_0E00410
uniprot id: H8X6M0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

1136231:CORT 0A09340
gene id: 1136231:CORT_0A09340
uniprot id: H8WYK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0E01810
gene id: 1136231:CORT_0E01810
uniprot id: H8X7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1136231:CORT 0C06020
gene id: 1136231:CORT_0C06020
uniprot id: H8X3B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1136231:CORT 0B09150
gene id: 1136231:CORT_0B09150
uniprot id: H8X0A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0B03860
gene id: 1136231:CORT_0B03860
uniprot id: H8X154
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0F02310
gene id: 1136231:CORT_0F02310
uniprot id: H8X8I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1136231:CORT 0C01900
gene id: 1136231:CORT_0C01900
uniprot id: H8X2L9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A03460
gene id: 1136231:CORT_0A03460
uniprot id: H8WWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.
messages: Nucleus

1136231:CORT 0E03060
gene id: 1136231:CORT_0E03060
uniprot id: H8X7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

1136231:CORT 0D07140
gene id: 1136231:CORT_0D07140
uniprot id: H8X5T9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A02920
gene id: 1136231:CORT_0A02920
uniprot id: H8WW58
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

1136231:CORT 0D03240
gene id: 1136231:CORT_0D03240
uniprot id: H8X575
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D03900
gene id: 1136231:CORT_0D03900
uniprot id: H8X5Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Required for vacuolar assembly and vacuolar traffic.
messages: Vacuole

1136231:CORT 0B03390
gene id: 1136231:CORT_0B03390
uniprot id: H8X108
names: Function
messages: Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.

1136231:CORT 0E01630
gene id: 1136231:CORT_0E01630
uniprot id: H8X7G6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E04630
gene id: 1136231:CORT_0E04630
uniprot id: H8X7B9
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1136231:CORT 0B10290
gene id: 1136231:CORT_0B10290
uniprot id: H8X212
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

1136231:CORT 0A00510
gene id: 1136231:CORT_0A00510
uniprot id: H8WVH2
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0E03250
gene id: 1136231:CORT_0E03250
uniprot id: H8X6Y5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1136231:CORT 0H00740
gene id: 1136231:CORT_0H00740
uniprot id: H8XBK3
names: Similarity
messages: Belongs to the TEL2 family.

1136231:CORT 0D01900
gene id: 1136231:CORT_0D01900
uniprot id: H8X4U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

1136231:CORT 0C07240
gene id: 1136231:CORT_0C07240
uniprot id: H8X4E2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1136231:CORT 0A08890
gene id: 1136231:CORT_0A08890
uniprot id: H8WYF8
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

1136231:CORT 0A10630
gene id: 1136231:CORT_0A10630
uniprot id: H8WXE3
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

1136231:CORT 0A02980
gene id: 1136231:CORT_0A02980
uniprot id: H8WW63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

1136231:CORT 0C01430
gene id: 1136231:CORT_0C01430
uniprot id: H8X2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

1136231:CORT 0A06350
gene id: 1136231:CORT_0A06350
uniprot id: H8WY74
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136231:CORT 0G03050
gene id: 1136231:CORT_0G03050
uniprot id: H8XA06
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G04380
gene id: 1136231:CORT_0G04380
uniprot id: H8XAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0D07370
gene id: 1136231:CORT_0D07370
uniprot id: H8X6F9
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0E00390
gene id: 1136231:CORT_0E00390
uniprot id: H8X6L8
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B03020
gene id: 1136231:CORT_0B03020
uniprot id: H8X0X6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E02290
gene id: 1136231:CORT_0E02290
uniprot id: H8X7N1
names: Similarity
messages: Belongs to the Luc7 family.

1136231:CORT 0F00510
gene id: 1136231:CORT_0F00510
uniprot id: H8X8Y2
names: Similarity
messages: Belongs to the GET4 family.

1136231:CORT 0B05660
gene id: 1136231:CORT_0B05660
uniprot id: H8WZS9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

1136231:CORT 0B06730
gene id: 1136231:CORT_0B06730
uniprot id: H8X1H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0D07610
gene id: 1136231:CORT_0D07610
uniprot id: H8X6I3
names: Similarity
messages: Belongs to the SEC6 family.

1136231:CORT 0A07270
gene id: 1136231:CORT_0A07270
uniprot id: H8WWX2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

1136231:CORT 0B09020
gene id: 1136231:CORT_0B09020
uniprot id: H8X094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL67 family.
messages: Mitochondrion

1136231:CORT 0C00950
gene id: 1136231:CORT_0C00950
uniprot id: H8X3J9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

1136231:CORT 0B04730
gene id: 1136231:CORT_0B04730
uniprot id: H8X1E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0D06760
gene id: 1136231:CORT_0D06760
uniprot id: H8X5Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.
messages: Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
messages: Nucleus

1136231:CORT 0C05630
gene id: 1136231:CORT_0C05630
uniprot id: H8X377
names: Similarity
messages: Belongs to the peptidase S33 family.

1136231:CORT 0A07670
gene id: 1136231:CORT_0A07670
uniprot id: H8WX13
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

1136231:CORT 0D02080
gene id: 1136231:CORT_0D02080
uniprot id: H8X4W4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H01200
gene id: 1136231:CORT_0H01200
uniprot id: H8XAY8
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

1136231:CORT 0A00230
gene id: 1136231:CORT_0A00230
uniprot id: H8WVE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1136231:CORT 0G00100
gene id: 1136231:CORT_0G00100
uniprot id: H8X9N5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F00300
gene id: 1136231:CORT_0F00300
uniprot id: H8X8W1
names: Similarity
messages: Belongs to the UPP synthase family.

1136231:CORT 0D04510
gene id: 1136231:CORT_0D04510
uniprot id: H8X643
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GMC oxidoreductase family.
messages: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.
messages: Peroxisome matrix

1136231:CORT 0G03950
gene id: 1136231:CORT_0G03950
uniprot id: H8XA95
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1136231:CORT 0F01000
gene id: 1136231:CORT_0F01000
uniprot id: H8X930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0B09760
gene id: 1136231:CORT_0B09760
uniprot id: H8X0G8
names: Similarity
messages: Belongs to the peptidase M16 family.

1136231:CORT 0B09330
gene id: 1136231:CORT_0B09330
uniprot id: H8X0C5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D07100
gene id: 1136231:CORT_0D07100
uniprot id: H8X5T5
names: Similarity
messages: Belongs to the PPP phosphatase family.

1136231:CORT 0D03230
gene id: 1136231:CORT_0D03230
uniprot id: H8X574
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

1136231:CORT 0B03510
gene id: 1136231:CORT_0B03510
uniprot id: H8X120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

1136231:CORT 0G03890
gene id: 1136231:CORT_0G03890
uniprot id: H8XA89
names: Similarity
messages: Belongs to the isochorismatase family.

1136231:CORT 0C05350
gene id: 1136231:CORT_0C05350
uniprot id: H8X349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

1136231:CORT 0C02700
gene id: 1136231:CORT_0C02700
uniprot id: H8X2U8
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

1136231:CORT 0C00610
gene id: 1136231:CORT_0C00610
uniprot id: H8X3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1136231:CORT 0C06570
gene id: 1136231:CORT_0C06570
uniprot id: H8X478
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A13030
gene id: 1136231:CORT_0A13030
uniprot id: H8WZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1136231:CORT 0D04110
gene id: 1136231:CORT_0D04110
uniprot id: H8X603
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

1136231:CORT 0B01620
gene id: 1136231:CORT_0B01620
uniprot id: H8X0J2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1136231:CORT 0H01400
gene id: 1136231:CORT_0H01400
uniprot id: H8XB05
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

1136231:CORT 0E01960
gene id: 1136231:CORT_0E01960
uniprot id: H8X7J9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1136231:CORT 0F03600
gene id: 1136231:CORT_0F03600
uniprot id: H8X9B7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.
messages: Prevacuolar compartment membrane
messages: multivesicular body membrane

1136231:CORT 0A08240
gene id: 1136231:CORT_0A08240
uniprot id: H8WY94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane

1136231:CORT 0C04650
gene id: 1136231:CORT_0C04650
uniprot id: H8X2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

1136231:CORT 0A00130
gene id: 1136231:CORT_0A00130
uniprot id: H8WZ60
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136231:CORT 0B07880
gene id: 1136231:CORT_0B07880
uniprot id: H8X1T8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1136231:CORT 0D03830
gene id: 1136231:CORT_0D03830
uniprot id: H8X5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

1136231:CORT 0D07620
gene id: 1136231:CORT_0D07620
uniprot id: H8X6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role (via N-terminus) in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. Further stabilizes spliceosome conformation for 3'-splice site docking (via C-terminus) promoting exon ligation.

1136231:CORT 0B08560
gene id: 1136231:CORT_0B08560
uniprot id: H8X048
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

1136231:CORT 0B05460
gene id: 1136231:CORT_0B05460
uniprot id: H8WZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Membrane
messages: nuclear pore complex

1136231:CORT 0C01850
gene id: 1136231:CORT_0C01850
uniprot id: H8X2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0E01280
gene id: 1136231:CORT_0E01280
uniprot id: H8X6V5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1136231:CORT 0B09380
gene id: 1136231:CORT_0B09380
uniprot id: H8X0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0E05010
gene id: 1136231:CORT_0E05010
uniprot id: H8X7Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0F03830
gene id: 1136231:CORT_0F03830
uniprot id: H8X9E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0F00560
gene id: 1136231:CORT_0F00560
uniprot id: H8X8Y7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H01580
gene id: 1136231:CORT_0H01580
uniprot id: H8XB23
names: Similarity
messages: Belongs to the DCC1 family.

1136231:CORT 0D04220
gene id: 1136231:CORT_0D04220
uniprot id: H8X614
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0B02480
gene id: 1136231:CORT_0B02480
uniprot id: H8X0S4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1136231:CORT 0B03060
gene id: 1136231:CORT_0B03060
uniprot id: H8X0X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1136231:CORT 0B04990
gene id: 1136231:CORT_0B04990
uniprot id: H8WZL2
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

1136231:CORT 0A08280
gene id: 1136231:CORT_0A08280
uniprot id: H8WY98
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G04100
gene id: 1136231:CORT_0G04100
uniprot id: H8XAB0
names: Similarity
messages: Belongs to the peptidase S8 family.

1136231:CORT 0D04070
gene id: 1136231:CORT_0D04070
uniprot id: H8X5Z9
names: Similarity
messages: Belongs to the threonine aldolase family.

1136231:CORT 0A06630
gene id: 1136231:CORT_0A06630
uniprot id: H8WWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

1136231:CORT 0B07800
gene id: 1136231:CORT_0B07800
uniprot id: H8X1T0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

1136231:CORT 0A09260
gene id: 1136231:CORT_0A09260
uniprot id: H8WYJ5
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0A09420
gene id: 1136231:CORT_0A09420
uniprot id: H8WYL2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F01890
gene id: 1136231:CORT_0F01890
uniprot id: H8X8E1
names: Function
names: Similarity
messages: Belongs to the CCM1 family.
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome.

1136231:CORT 0A07970
gene id: 1136231:CORT_0A07970
uniprot id: H8WX43
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0C03750
gene id: 1136231:CORT_0C03750
uniprot id: H8X3W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG27 family.
messages: Cytoplasmic vesicle membrane
messages: Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9.
messages: Golgi apparatus membrane
messages: Membrane
messages: Preautophagosomal structure membrane

1136231:CORT 0G01100
gene id: 1136231:CORT_0G01100
uniprot id: H8X9Y1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the alternative oxidase family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.

1136231:CORT 0C02460
gene id: 1136231:CORT_0C02460
uniprot id: H8X2S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

1136231:CORT 0B06050
gene id: 1136231:CORT_0B06050
uniprot id: H8WZW9
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

1136231:CORT 0A06760
gene id: 1136231:CORT_0A06760
uniprot id: H8WWS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Nucleus

1136231:CORT 0B09890
gene id: 1136231:CORT_0B09890
uniprot id: H8X0I1
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1136231:CORT 0F03250
gene id: 1136231:CORT_0F03250
uniprot id: H8X8S4
names: Similarity
messages: Belongs to the arginase family.

1136231:CORT 0A08420
gene id: 1136231:CORT_0A08420
uniprot id: H8WYB1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

1136231:CORT 0E03160
gene id: 1136231:CORT_0E03160
uniprot id: H8X6X7
names: Similarity
messages: Belongs to the RAD52 family.

1136231:CORT 0E04180
gene id: 1136231:CORT_0E04180
uniprot id: H8X776
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1136231:CORT 0A09130
gene id: 1136231:CORT_0A09130
uniprot id: H8WYI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal cytochrome c oxidase subunit 7a family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0A00880
gene id: 1136231:CORT_0A00880
uniprot id: H8WVK6
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

1136231:CORT 0C05170
gene id: 1136231:CORT_0C05170
uniprot id: H8X331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0A02460
gene id: 1136231:CORT_0A02460
uniprot id: H8WW13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

1136231:CORT 0H00470
gene id: 1136231:CORT_0H00470
uniprot id: H8XBH6
names: Similarity
messages: Belongs to the HIT family.

1136231:CORT 0D05170
gene id: 1136231:CORT_0D05170
uniprot id: H8X6A9
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0A06120
gene id: 1136231:CORT_0A06120
uniprot id: H8WY52
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B10800
gene id: 1136231:CORT_0B10800
uniprot id: H8X260
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

1136231:CORT 0A04390
gene id: 1136231:CORT_0A04390
uniprot id: H8WWK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0D02340
gene id: 1136231:CORT_0D02340
uniprot id: H8X4Y9
names: Similarity
messages: Belongs to the NXF family.

1136231:CORT 0D00160
gene id: 1136231:CORT_0D00160
uniprot id: H8X5V1
names: Similarity
messages: Belongs to the VPS52 family.

1136231:CORT 0F03790
gene id: 1136231:CORT_0F03790
uniprot id: H8X9D6
names: Subcellular Location Annotation
messages: telomere

1136231:CORT 0E02370
gene id: 1136231:CORT_0E02370
uniprot id: H8X7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

1136231:CORT 0E05350
gene id: 1136231:CORT_0E05350
uniprot id: H8X821
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Cytoplasm
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
messages: Interacts with NAR1.
messages: Nucleus

1136231:CORT 0A07160
gene id: 1136231:CORT_0A07160
uniprot id: H8WWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1136231:CORT 0A08670
gene id: 1136231:CORT_0A08670
uniprot id: H8WYD6
names: Subcellular Location Annotation
messages: Peroxisome membrane
messages: cytosol

1136231:CORT 0A03030
gene id: 1136231:CORT_0A03030
uniprot id: H8WW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B00350
gene id: 1136231:CORT_0B00350
uniprot id: H8WZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

1136231:CORT 0A03150
gene id: 1136231:CORT_0A03150
uniprot id: H8WW79
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

1136231:CORT 0E02380
gene id: 1136231:CORT_0E02380
uniprot id: H8X7P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1136231:CORT 0E01990
gene id: 1136231:CORT_0E01990
uniprot id: H8X7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.

1136231:CORT 0D07250
gene id: 1136231:CORT_0D07250
uniprot id: H8X6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

1136231:CORT 0A05120
gene id: 1136231:CORT_0A05120
uniprot id: H8WXV3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1136231:CORT 0F03200
gene id: 1136231:CORT_0F03200
uniprot id: H8X8R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

1136231:CORT 0B08580
gene id: 1136231:CORT_0B08580
uniprot id: H8X050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

1136231:CORT 0E01680
gene id: 1136231:CORT_0E01680
uniprot id: H8X7H1
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1136231:CORT 0A06920
gene id: 1136231:CORT_0A06920
uniprot id: H8WWT7
names: Similarity
messages: Belongs to the CEF1 family.

1136231:CORT 0E06120
gene id: 1136231:CORT_0E06120
uniprot id: H8X895
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane
messages: Monomer.

1136231:CORT 0C03610
gene id: 1136231:CORT_0C03610
uniprot id: H8X3U8
names: Similarity
messages: Belongs to the UPF0045 family.

1136231:CORT 0B03170
gene id: 1136231:CORT_0B03170
uniprot id: H8X0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1136231:CORT 0E01080
gene id: 1136231:CORT_0E01080
uniprot id: H8X6T6
names: Function
names: Similarity
names: Subunit
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.
messages: Monomer.

1136231:CORT 0F02260
gene id: 1136231:CORT_0F02260
uniprot id: H8X8H6
names: Similarity
messages: Belongs to the p23/wos2 family.

1136231:CORT 0D00690
gene id: 1136231:CORT_0D00690
uniprot id: H8X4H5
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

1136231:CORT 0A09430
gene id: 1136231:CORT_0A09430
uniprot id: H8WYL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0H00960
gene id: 1136231:CORT_0H00960
uniprot id: H8XAW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX20 family.
messages: Involved in the assembly of the cytochrome c oxidase complex.
messages: Mitochondrion inner membrane

1136231:CORT 0F03550
gene id: 1136231:CORT_0F03550
uniprot id: H8X9B4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1136231:CORT 0B01250
gene id: 1136231:CORT_0B01250
uniprot id: H8WZH6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1136231:CORT 0H00520
gene id: 1136231:CORT_0H00520
uniprot id: H8XBI1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1136231:CORT 0A05040
gene id: 1136231:CORT_0A05040
uniprot id: H8WXU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0G03400
gene id: 1136231:CORT_0G03400
uniprot id: H8XA39
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0A12110
gene id: 1136231:CORT_0A12110
uniprot id: H8WYW4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136231:CORT 0C01360
gene id: 1136231:CORT_0C01360
uniprot id: H8X2G6
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

1136231:CORT 0E04290
gene id: 1136231:CORT_0E04290
uniprot id: H8X787
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0F04480
gene id: 1136231:CORT_0F04480
uniprot id: H8X9K6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

1136231:CORT 0D06230
gene id: 1136231:CORT_0D06230
uniprot id: H8X5K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B11110
gene id: 1136231:CORT_0B11110
uniprot id: H8X288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

1136231:CORT 0A13180
gene id: 1136231:CORT_0A13180
uniprot id: H8WXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

1136231:CORT 0B09620
gene id: 1136231:CORT_0B09620
uniprot id: H8X0F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

1136231:CORT 0A02660
gene id: 1136231:CORT_0A02660
uniprot id: H8WW33
names: Similarity
messages: Belongs to the ERT1/acuK family.

1136231:CORT 0G00590
gene id: 1136231:CORT_0G00590
uniprot id: H8X9T2
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

1136231:CORT 0A11130
gene id: 1136231:CORT_0A11130
uniprot id: H8WXJ2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A07920
gene id: 1136231:CORT_0A07920
uniprot id: H8WX38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

1136231:CORT 0D04790
gene id: 1136231:CORT_0D04790
uniprot id: H8X671
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

1136231:CORT 0F02410
gene id: 1136231:CORT_0F02410
uniprot id: H8X8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: kinetochore
messages: spindle

1136231:CORT 0E06580
gene id: 1136231:CORT_0E06580
uniprot id: H8X7E5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B09050
gene id: 1136231:CORT_0B09050
uniprot id: H8X097
names: Similarity
messages: Belongs to the AAA ATPase family.

1136231:CORT 0F01910
gene id: 1136231:CORT_0F01910
uniprot id: H8X8E3
names: Similarity
messages: Belongs to the CCZ1 family.

1136231:CORT 0C06900
gene id: 1136231:CORT_0C06900
uniprot id: H8X4B0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

1136231:CORT 0B09700
gene id: 1136231:CORT_0B09700
uniprot id: H8X0G2
names: Similarity
messages: Belongs to the UPF0047 family.

1136231:CORT 0E04570
gene id: 1136231:CORT_0E04570
uniprot id: H8X7B4
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

1136231:CORT 0A08790
gene id: 1136231:CORT_0A08790
uniprot id: H8WYE8
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0G02470
gene id: 1136231:CORT_0G02470
uniprot id: H8XAS7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1136231:CORT 0D01850
gene id: 1136231:CORT_0D01850
uniprot id: H8X4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1136231:CORT 0F03610
gene id: 1136231:CORT_0F03610
uniprot id: H8X9B8
names: Similarity
messages: Belongs to the pyridoxine kinase family.

1136231:CORT 0B04250
gene id: 1136231:CORT_0B04250
uniprot id: H8X192
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Endosome

1136231:CORT 0G02310
gene id: 1136231:CORT_0G02310
uniprot id: H8XAR1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1136231:CORT 0A10930
gene id: 1136231:CORT_0A10930
uniprot id: H8WXH2
names: Similarity
messages: Belongs to the AAA ATPase family.

1136231:CORT 0D05050
gene id: 1136231:CORT_0D05050
uniprot id: H8X697
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A10500
gene id: 1136231:CORT_0A10500
uniprot id: H8WXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

1136231:CORT 0E00650
gene id: 1136231:CORT_0E00650
uniprot id: H8X6P3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

1136231:CORT 0A08900
gene id: 1136231:CORT_0A08900
uniprot id: H8WYF9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM10 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

1136231:CORT 0G01600
gene id: 1136231:CORT_0G01600
uniprot id: H8XAJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1136231:CORT 0F00580
gene id: 1136231:CORT_0F00580
uniprot id: H8X8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0H01210
gene id: 1136231:CORT_0H01210
uniprot id: H8XAY9
names: Similarity
messages: Belongs to the IWR1/SLC7A6OS family.

1136231:CORT 0B10150
gene id: 1136231:CORT_0B10150
uniprot id: H8X1Z8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A07460
gene id: 1136231:CORT_0A07460
uniprot id: H8WWZ1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B02420
gene id: 1136231:CORT_0B02420
uniprot id: H8X0R8
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1136231:CORT 0E04620
gene id: 1136231:CORT_0E04620
uniprot id: H8X7B8
names: Similarity
messages: Belongs to the GST superfamily.

1136231:CORT 0B07120
gene id: 1136231:CORT_0B07120
uniprot id: H8X1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

1136231:CORT 0A13210
gene id: 1136231:CORT_0A13210
uniprot id: H8WXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0D06840
gene id: 1136231:CORT_0D06840
uniprot id: H8X5Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

1136231:CORT 0C01870
gene id: 1136231:CORT_0C01870
uniprot id: H8X2L6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

1136231:CORT 0F04530
gene id: 1136231:CORT_0F04530
uniprot id: H8X9L1
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

1136231:CORT 0E00520
gene id: 1136231:CORT_0E00520
uniprot id: H8X6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

1136231:CORT 0B04270
gene id: 1136231:CORT_0B04270
uniprot id: H8X194
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1136231:CORT 0B09120
gene id: 1136231:CORT_0B09120
uniprot id: H8X0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

1136231:CORT 0A11290
gene id: 1136231:CORT_0A11290
uniprot id: H8WXK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1136231:CORT 0D06010
gene id: 1136231:CORT_0D06010
uniprot id: H8X5I2
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

1136231:CORT 0G03800
gene id: 1136231:CORT_0G03800
uniprot id: H8XA80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0A13340
gene id: 1136231:CORT_0A13340
uniprot id: H8WXP4
names: Similarity
messages: Belongs to the epsin family.

1136231:CORT 0E01840
gene id: 1136231:CORT_0E01840
uniprot id: H8X7I7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1136231:CORT 0C03360
gene id: 1136231:CORT_0C03360
uniprot id: H8X3S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

1136231:CORT 0D00840
gene id: 1136231:CORT_0D00840
uniprot id: H8X4J0
names: Similarity
messages: Belongs to the MGMT family.

1136231:CORT 0A03170
gene id: 1136231:CORT_0A03170
uniprot id: H8WW81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

1136231:CORT 0A06290
gene id: 1136231:CORT_0A06290
uniprot id: H8WY68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

1136231:CORT 0E01380
gene id: 1136231:CORT_0E01380
uniprot id: H8X6W5
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

1136231:CORT 0G00300
gene id: 1136231:CORT_0G00300
uniprot id: H8X9Q4
names: Similarity
messages: Belongs to the peptidase M24B family.

1136231:CORT 0F00250
gene id: 1136231:CORT_0F00250
uniprot id: H8X8V6
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

1136231:CORT 0D00700
gene id: 1136231:CORT_0D00700
uniprot id: H8X4H6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1136231:CORT 0B04880
gene id: 1136231:CORT_0B04880
uniprot id: H8X1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: Cell membrane
messages: Vacuole membrane

1136231:CORT 0C03780
gene id: 1136231:CORT_0C03780
uniprot id: H8X3W5
names: Similarity
messages: Belongs to the peptidase C48 family.

1136231:CORT 0A08650
gene id: 1136231:CORT_0A08650
uniprot id: H8WYD4
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

1136231:CORT 0F02900
gene id: 1136231:CORT_0F02900
uniprot id: H8X8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1136231:CORT 0B02940
gene id: 1136231:CORT_0B02940
uniprot id: H8X0W9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A07150
gene id: 1136231:CORT_0A07150
uniprot id: H8WWW0
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

1136231:CORT 0G04420
gene id: 1136231:CORT_0G04420
uniprot id: H8XAE2
names: Similarity
messages: Belongs to the SAPS family.

1136231:CORT 0A01310
gene id: 1136231:CORT_0A01310
uniprot id: H8WVP9
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1136231:CORT 0E03810
gene id: 1136231:CORT_0E03810
uniprot id: H8X741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1136231:CORT 0C07120
gene id: 1136231:CORT_0C07120
uniprot id: H8X4D1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E05000
gene id: 1136231:CORT_0E05000
uniprot id: H8X7Y5
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

1136231:CORT 0D05450
gene id: 1136231:CORT_0D05450
uniprot id: H8X6D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

1136231:CORT 0A07820
gene id: 1136231:CORT_0A07820
uniprot id: H8WX28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-3 family.
messages: Membrane
messages: Peroxisome membrane

1136231:CORT 0A09460
gene id: 1136231:CORT_0A09460
uniprot id: H8WYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

1136231:CORT 0G02500
gene id: 1136231:CORT_0G02500
uniprot id: H8XAT0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1136231:CORT 0B05060
gene id: 1136231:CORT_0B05060
uniprot id: H8WZL9
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0E00900
gene id: 1136231:CORT_0E00900
uniprot id: H8X6R8
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1136231:CORT 0D02470
gene id: 1136231:CORT_0D02470
uniprot id: H8X502
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E05970
gene id: 1136231:CORT_0E05970
uniprot id: H8X881
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1136231:CORT 0C05880
gene id: 1136231:CORT_0C05880
uniprot id: H8X3A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Component of the 20S proteasome chaperone.
messages: Involved in 20S proteasome assembly.

1136231:CORT 0B02670
gene id: 1136231:CORT_0B02670
uniprot id: H8X0U3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: telomere

1136231:CORT 0F02040
gene id: 1136231:CORT_0F02040
uniprot id: H8X8F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0C01570
gene id: 1136231:CORT_0C01570
uniprot id: H8X2I7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1136231:CORT 0E03280
gene id: 1136231:CORT_0E03280
uniprot id: H8X6Y8
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0A07610
gene id: 1136231:CORT_0A07610
uniprot id: H8WX07
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

1136231:CORT 0D03300
gene id: 1136231:CORT_0D03300
uniprot id: H8X580
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1136231:CORT 0D00370
gene id: 1136231:CORT_0D00370
uniprot id: H8X5X2
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1136231:CORT 0C05720
gene id: 1136231:CORT_0C05720
uniprot id: H8X386
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

1136231:CORT 0H00290
gene id: 1136231:CORT_0H00290
uniprot id: H8XBF9
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

1136231:CORT 0C04480
gene id: 1136231:CORT_0C04480
uniprot id: H8X2W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Mitochondrion inner membrane

1136231:CORT 0B06450
gene id: 1136231:CORT_0B06450
uniprot id: H8X009
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0B10520
gene id: 1136231:CORT_0B10520
uniprot id: H8X233
names: Similarity
messages: Belongs to the CIA30 family.

1136231:CORT 0F04190
gene id: 1136231:CORT_0F04190
uniprot id: H8X9H7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.
messages: Prevacuolar compartment membrane
messages: multivesicular body membrane

1136231:CORT 0E02820
gene id: 1136231:CORT_0E02820
uniprot id: H8X7T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

1136231:CORT 0C02230
gene id: 1136231:CORT_0C02230
uniprot id: H8X2Q2
names: Similarity
messages: Belongs to the GST superfamily.

1136231:CORT 0A09120
gene id: 1136231:CORT_0A09120
uniprot id: H8WYI1
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1136231:CORT 0A01970
gene id: 1136231:CORT_0A01970
uniprot id: H8WVW4
names: Similarity
messages: Belongs to the CWC22 family.

1136231:CORT 0B08110
gene id: 1136231:CORT_0B08110
uniprot id: H8X1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DLT1 family.
messages: Membrane
messages: Required for growth under high-pressure and low-temperature conditions.

1136231:CORT 0B03360
gene id: 1136231:CORT_0B03360
uniprot id: H8X105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

1136231:CORT 0B00880
gene id: 1136231:CORT_0B00880
uniprot id: H8WZE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0C05790
gene id: 1136231:CORT_0C05790
uniprot id: H8X392
names: Similarity
messages: Belongs to the actin family.

1136231:CORT 0D01370
gene id: 1136231:CORT_0D01370
uniprot id: H8X4P3
names: Function
names: Similarity
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

1136231:CORT 0H00420
gene id: 1136231:CORT_0H00420
uniprot id: H8XBH1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1136231:CORT 0G03310
gene id: 1136231:CORT_0G03310
uniprot id: H8XA31
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1136231:CORT 0G02860
gene id: 1136231:CORT_0G02860
uniprot id: H8X9Y8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0C05300
gene id: 1136231:CORT_0C05300
uniprot id: H8X344
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

1136231:CORT 0H01850
gene id: 1136231:CORT_0H01850
uniprot id: H8XB49
names: Similarity
messages: Belongs to the BolA/IbaG family.

1136231:CORT 0B03690
gene id: 1136231:CORT_0B03690
uniprot id: H8X137
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0E01850
gene id: 1136231:CORT_0E01850
uniprot id: H8X7I8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

1136231:CORT 0D04390
gene id: 1136231:CORT_0D04390
uniprot id: H8X631
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

1136231:CORT 0E02390
gene id: 1136231:CORT_0E02390
uniprot id: H8X7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

1136231:CORT 0A13310
gene id: 1136231:CORT_0A13310
uniprot id: H8WXP1
names: Similarity
messages: Belongs to the proteasome subunit S11 family.

1136231:CORT 0B05130
gene id: 1136231:CORT_0B05130
uniprot id: H8WZM6
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1136231:CORT 0A11690
gene id: 1136231:CORT_0A11690
uniprot id: H8WYS2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H00880
gene id: 1136231:CORT_0H00880
uniprot id: H8XBL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane
messages: Required for vacuolar protein sorting.

1136231:CORT 0C03640
gene id: 1136231:CORT_0C03640
uniprot id: H8X3V1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C05150
gene id: 1136231:CORT_0C05150
uniprot id: H8X329
names: Similarity
messages: Belongs to the AIM23 family.

1136231:CORT 0D04910
gene id: 1136231:CORT_0D04910
uniprot id: H8X683
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

1136231:CORT 0F01840
gene id: 1136231:CORT_0F01840
uniprot id: H8X8D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0B02070
gene id: 1136231:CORT_0B02070
uniprot id: H8X0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUF2 family.
messages: Nucleus
messages: kinetochore

1136231:CORT 0D02730
gene id: 1136231:CORT_0D02730
uniprot id: H8X525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1136231:CORT 0B11210
gene id: 1136231:CORT_0B11210
uniprot id: H8X298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

1136231:CORT 0A11220
gene id: 1136231:CORT_0A11220
uniprot id: H8WXK1
names: Similarity
messages: Belongs to the BMT family.

1136231:CORT 0B08940
gene id: 1136231:CORT_0B08940
uniprot id: H8X086
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

1136231:CORT 0F00920
gene id: 1136231:CORT_0F00920
uniprot id: H8X923
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1136231:CORT 0A09840
gene id: 1136231:CORT_0A09840
uniprot id: H8WX64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

1136231:CORT 0E05820
gene id: 1136231:CORT_0E05820
uniprot id: H8X866
names: Similarity
messages: Belongs to the cyclin family.

1136231:CORT 0E05900
gene id: 1136231:CORT_0E05900
uniprot id: H8X874
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136231:CORT 0D00990
gene id: 1136231:CORT_0D00990
uniprot id: H8X4K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

1136231:CORT 0H01010
gene id: 1136231:CORT_0H01010
uniprot id: H8XAW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1136231:CORT 0G03110
gene id: 1136231:CORT_0G03110
uniprot id: H8XA12
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136231:CORT 0B02720
gene id: 1136231:CORT_0B02720
uniprot id: H8X0U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1136231:CORT 0G01880
gene id: 1136231:CORT_0G01880
uniprot id: H8XAM1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1136231:CORT 0B03000
gene id: 1136231:CORT_0B03000
uniprot id: H8X0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Nucleus

1136231:CORT 0D06720
gene id: 1136231:CORT_0D06720
uniprot id: H8X5P8
names: Similarity
messages: Belongs to the cullin family.

1136231:CORT 0A04720
gene id: 1136231:CORT_0A04720
uniprot id: H8WXR3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1136231:CORT 0E05920
gene id: 1136231:CORT_0E05920
uniprot id: H8X876
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

1136231:CORT 0A10430
gene id: 1136231:CORT_0A10430
uniprot id: H8WXC3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1136231:CORT 0H00190
gene id: 1136231:CORT_0H00190
uniprot id: H8XBE9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A07800
gene id: 1136231:CORT_0A07800
uniprot id: H8WX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

1136231:CORT 0E04890
gene id: 1136231:CORT_0E04890
uniprot id: H8X7X4
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

1136231:CORT 0F03960
gene id: 1136231:CORT_0F03960
uniprot id: H8X9F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

1136231:CORT 0A13190
gene id: 1136231:CORT_0A13190
uniprot id: H8WXM9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

1136231:CORT 0A09850
gene id: 1136231:CORT_0A09850
uniprot id: H8WX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP6 family.
messages: nucleolus

1136231:CORT 0A01250
gene id: 1136231:CORT_0A01250
uniprot id: H8WVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1136231:CORT 0C01030
gene id: 1136231:CORT_0C01030
uniprot id: H8X3K7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D04300
gene id: 1136231:CORT_0D04300
uniprot id: H8X622
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1136231:CORT 0A03100
gene id: 1136231:CORT_0A03100
uniprot id: H8WW75
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G01770
gene id: 1136231:CORT_0G01770
uniprot id: H8XAL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1136231:CORT 0G02000
gene id: 1136231:CORT_0G02000
uniprot id: H8XAN1
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

1136231:CORT 0C03630
gene id: 1136231:CORT_0C03630
uniprot id: H8X3V0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

1136231:CORT 0D02130
gene id: 1136231:CORT_0D02130
uniprot id: H8X4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

1136231:CORT 0A12960
gene id: 1136231:CORT_0A12960
uniprot id: H8WZ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0D00300
gene id: 1136231:CORT_0D00300
uniprot id: H8X5W5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B04460
gene id: 1136231:CORT_0B04460
uniprot id: H8X1B4
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1136231:CORT 0E06560
gene id: 1136231:CORT_0E06560
uniprot id: H8X7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

1136231:CORT 0A04570
gene id: 1136231:CORT_0A04570
uniprot id: H8WWM1
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0G02980
gene id: 1136231:CORT_0G02980
uniprot id: H8X9Z9
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0C04200
gene id: 1136231:CORT_0C04200
uniprot id: H8X405
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

1136231:CORT 0A00580
gene id: 1136231:CORT_0A00580
uniprot id: H8WVH8
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

1136231:CORT 0G02590
gene id: 1136231:CORT_0G02590
uniprot id: H8XAT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0E01750
gene id: 1136231:CORT_0E01750
uniprot id: H8X7H8
names: Function
names: Similarity
messages: Belongs to the IRC6 family.
messages: Involved in gross chromosomal rearrangements (GCRs) and telomere healing.

1136231:CORT 0B06890
gene id: 1136231:CORT_0B06890
uniprot id: H8X1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0B10240
gene id: 1136231:CORT_0B10240
uniprot id: H8X207
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

1136231:CORT 0D01290
gene id: 1136231:CORT_0D01290
uniprot id: H8X4N5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136231:CORT 0G02630
gene id: 1136231:CORT_0G02630
uniprot id: H8XAU3
names: Similarity
messages: Belongs to the type-1 OGG1 family.

1136231:CORT 0D04380
gene id: 1136231:CORT_0D04380
uniprot id: H8X630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

1136231:CORT 0D01620
gene id: 1136231:CORT_0D01620
uniprot id: H8X4R8
names: Function
names: Similarity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.

1136231:CORT 0B06260
gene id: 1136231:CORT_0B06260
uniprot id: H8WZZ0
names: Similarity
messages: Belongs to the SEN15 family.

1136231:CORT 0C01930
gene id: 1136231:CORT_0C01930
uniprot id: H8X2M2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of UBP8 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

1136231:CORT 0C05660
gene id: 1136231:CORT_0C05660
uniprot id: H8X380
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0C02030
gene id: 1136231:CORT_0C02030
uniprot id: H8X2N2
names: Similarity
messages: Belongs to the peptidase C19 family.

1136231:CORT 0G02560
gene id: 1136231:CORT_0G02560
uniprot id: H8XAT6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1136231:CORT 0A12780
gene id: 1136231:CORT_0A12780
uniprot id: H8WZ30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WRB/GET1 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

1136231:CORT 0B00860
gene id: 1136231:CORT_0B00860
uniprot id: H8WZD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0F03240
gene id: 1136231:CORT_0F03240
uniprot id: H8X8S3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1136231:CORT 0E04190
gene id: 1136231:CORT_0E04190
uniprot id: H8X777
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

1136231:CORT 0F02920
gene id: 1136231:CORT_0F02920
uniprot id: H8X8P1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136231:CORT 0D00780
gene id: 1136231:CORT_0D00780
uniprot id: H8X4I4
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

1136231:CORT 0A07770
gene id: 1136231:CORT_0A07770
uniprot id: H8WX23
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E02450
gene id: 1136231:CORT_0E02450
uniprot id: H8X7P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

1136231:CORT 0A03230
gene id: 1136231:CORT_0A03230
uniprot id: H8WW87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Endosome membrane
messages: Membrane

1136231:CORT 0G03160
gene id: 1136231:CORT_0G03160
uniprot id: H8XA16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

1136231:CORT 0A02210
gene id: 1136231:CORT_0A02210
uniprot id: H8WVY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1136231:CORT 0D01890
gene id: 1136231:CORT_0D01890
uniprot id: H8X4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: nucleolus

1136231:CORT 0A03920
gene id: 1136231:CORT_0A03920
uniprot id: H8WWF6
names: Similarity
messages: Belongs to the malate synthase family.

1136231:CORT 0D03200
gene id: 1136231:CORT_0D03200
uniprot id: H8X571
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1136231:CORT 0B04470
gene id: 1136231:CORT_0B04470
uniprot id: H8X1B5
names: Similarity
messages: Belongs to the GcvT family. CAF17 subfamily.

1136231:CORT 0E06380
gene id: 1136231:CORT_0E06380
uniprot id: H8X8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Nucleus

1136231:CORT 0B01430
gene id: 1136231:CORT_0B01430
uniprot id: H8WZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1136231:CORT 0G02940
gene id: 1136231:CORT_0G02940
uniprot id: H8X9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

1136231:CORT 0A09360
gene id: 1136231:CORT_0A09360
uniprot id: H8WYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1136231:CORT 0A10640
gene id: 1136231:CORT_0A10640
uniprot id: H8WXE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

1136231:CORT 0H01240
gene id: 1136231:CORT_0H01240
uniprot id: H8XAZ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0D04850
gene id: 1136231:CORT_0D04850
uniprot id: H8X677
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1136231:CORT 0E02480
gene id: 1136231:CORT_0E02480
uniprot id: H8X7Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

1136231:CORT 0D04640
gene id: 1136231:CORT_0D04640
uniprot id: H8X656
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1136231:CORT 0C01990
gene id: 1136231:CORT_0C01990
uniprot id: H8X2M8
names: Similarity
messages: Belongs to the PAF1 family.

1136231:CORT 0E02160
gene id: 1136231:CORT_0E02160
uniprot id: H8X7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0E00210
gene id: 1136231:CORT_0E00210
uniprot id: H8X6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1136231:CORT 0D06150
gene id: 1136231:CORT_0D06150
uniprot id: H8X5J5
names: Similarity
messages: Belongs to the VAC14 family.

1136231:CORT 0F00350
gene id: 1136231:CORT_0F00350
uniprot id: H8X8W6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0B06030
gene id: 1136231:CORT_0B06030
uniprot id: H8WZW7
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

1136231:CORT 0G03130
gene id: 1136231:CORT_0G03130
uniprot id: H8XA14
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H01940
gene id: 1136231:CORT_0H01940
uniprot id: H8XB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: Mitochondrion

1136231:CORT 0E03430
gene id: 1136231:CORT_0E03430
uniprot id: H8X703
names: Similarity
messages: Belongs to the peptidase S10 family.

1136231:CORT 0G00520
gene id: 1136231:CORT_0G00520
uniprot id: H8X9S6
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

1136231:CORT 0A05200
gene id: 1136231:CORT_0A05200
uniprot id: H8WXW1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D00940
gene id: 1136231:CORT_0D00940
uniprot id: H8X4K0
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1136231:CORT 0D03590
gene id: 1136231:CORT_0D03590
uniprot id: H8X5A7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1136231:CORT 0B00240
gene id: 1136231:CORT_0B00240
uniprot id: H8WZ79
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136231:CORT 0C05800
gene id: 1136231:CORT_0C05800
uniprot id: H8X393
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1136231:CORT 0E02430
gene id: 1136231:CORT_0E02430
uniprot id: H8X7P5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1136231:CORT 0B10640
gene id: 1136231:CORT_0B10640
uniprot id: H8X244
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1136231:CORT 0C07310
gene id: 1136231:CORT_0C07310
uniprot id: H8X4E9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1136231:CORT 0D06470
gene id: 1136231:CORT_0D06470
uniprot id: H8X5M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

1136231:CORT 0A10550
gene id: 1136231:CORT_0A10550
uniprot id: H8WXD5
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1136231:CORT 0A03720
gene id: 1136231:CORT_0A03720
uniprot id: H8WWD6
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1136231:CORT 0D07030
gene id: 1136231:CORT_0D07030
uniprot id: H8X5S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1136231:CORT 0G03290
gene id: 1136231:CORT_0G03290
uniprot id: H8XA29
names: Similarity
messages: Belongs to the Tom22 family.

1136231:CORT 0F00230
gene id: 1136231:CORT_0F00230
uniprot id: H8X8V4
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1136231:CORT 0D01930
gene id: 1136231:CORT_0D01930
uniprot id: H8X4U9
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

1136231:CORT 0B02390
gene id: 1136231:CORT_0B02390
uniprot id: H8X0R5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

1136231:CORT 0B07410
gene id: 1136231:CORT_0B07410
uniprot id: H8X1P2
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1136231:CORT 0F03930
gene id: 1136231:CORT_0F03930
uniprot id: H8X9F1
names: Similarity
messages: Belongs to the FES1 family.

1136231:CORT 0A00620
gene id: 1136231:CORT_0A00620
uniprot id: H8WVI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1136231:CORT 0F02960
gene id: 1136231:CORT_0F02960
uniprot id: H8X8P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

1136231:CORT 0E05720
gene id: 1136231:CORT_0E05720
uniprot id: H8X857
names: Similarity
messages: Belongs to the OSBP family.

1136231:CORT 0A11300
gene id: 1136231:CORT_0A11300
uniprot id: H8WXK9
names: Similarity
messages: Belongs to the peptidase C19 family.

1136231:CORT 0B04620
gene id: 1136231:CORT_0B04620
uniprot id: H8X1D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0E01780
gene id: 1136231:CORT_0E01780
uniprot id: H8X7I1
names: Function
names: Subcellular Location Annotation
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
messages: Mitochondrion inner membrane

1136231:CORT 0F00320
gene id: 1136231:CORT_0F00320
uniprot id: H8X8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1136231:CORT 0E04210
gene id: 1136231:CORT_0E04210
uniprot id: H8X779
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

1136231:CORT 0C03060
gene id: 1136231:CORT_0C03060
uniprot id: H8X3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

1136231:CORT 0H02090
gene id: 1136231:CORT_0H02090
uniprot id: H8XB71
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B11510
gene id: 1136231:CORT_0B11510
uniprot id: H8X2C8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1136231:CORT 0A11030
gene id: 1136231:CORT_0A11030
uniprot id: H8WXI2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1136231:CORT 0E06480
gene id: 1136231:CORT_0E06480
uniprot id: H8X7D5
names: Similarity
messages: Belongs to the peptidase M18 family.

1136231:CORT 0D02260
gene id: 1136231:CORT_0D02260
uniprot id: H8X4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

1136231:CORT 0C03680
gene id: 1136231:CORT_0C03680
uniprot id: H8X3V5
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0H01660
gene id: 1136231:CORT_0H01660
uniprot id: H8XB31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0G01170
gene id: 1136231:CORT_0G01170
uniprot id: H8XAF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

1136231:CORT 0C04910
gene id: 1136231:CORT_0C04910
uniprot id: H8X305
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

1136231:CORT 0F02990
gene id: 1136231:CORT_0F02990
uniprot id: H8X8P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1136231:CORT 0G02020
gene id: 1136231:CORT_0G02020
uniprot id: H8XAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1136231:CORT 0B02840
gene id: 1136231:CORT_0B02840
uniprot id: H8X0W0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A03420
gene id: 1136231:CORT_0A03420
uniprot id: H8WWA6
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

1136231:CORT 0D06030
gene id: 1136231:CORT_0D06030
uniprot id: H8X5I3
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0B11020
gene id: 1136231:CORT_0B11020
uniprot id: H8X279
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

1136231:CORT 0D03030
gene id: 1136231:CORT_0D03030
uniprot id: H8X555
names: Similarity
messages: Belongs to the SUN family.

1136231:CORT 0D04320
gene id: 1136231:CORT_0D04320
uniprot id: H8X624
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1136231:CORT 0A08720
gene id: 1136231:CORT_0A08720
uniprot id: H8WYE1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

1136231:CORT 0A00390
gene id: 1136231:CORT_0A00390
uniprot id: H8WVG0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H00720
gene id: 1136231:CORT_0H00720
uniprot id: H8XBK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0C04010
gene id: 1136231:CORT_0C04010
uniprot id: H8X3Y7
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus
messages: Ubiquitination of histone H2B to form H2BK123ub1 is required for efficient DOT1 methyltransferase activity on histone H3.

1136231:CORT 0E06140
gene id: 1136231:CORT_0E06140
uniprot id: H8X897
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1136231:CORT 0A09280
gene id: 1136231:CORT_0A09280
uniprot id: H8WYJ7
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

1136231:CORT 0B08520
gene id: 1136231:CORT_0B08520
uniprot id: H8X044
names: Similarity
messages: Belongs to the SIP5 family.

1136231:CORT 0E02360
gene id: 1136231:CORT_0E02360
uniprot id: H8X7N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

1136231:CORT 0C02120
gene id: 1136231:CORT_0C02120
uniprot id: H8X2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1136231:CORT 0D07010
gene id: 1136231:CORT_0D07010
uniprot id: H8X5S6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1136231:CORT 0B01190
gene id: 1136231:CORT_0B01190
uniprot id: H8WZH1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1136231:CORT 0H00350
gene id: 1136231:CORT_0H00350
uniprot id: H8XBG5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1136231:CORT 0A05370
gene id: 1136231:CORT_0A05370
uniprot id: H8WXX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

1136231:CORT 0D01140
gene id: 1136231:CORT_0D01140
uniprot id: H8X4M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1136231:CORT 0A03580
gene id: 1136231:CORT_0A03580
uniprot id: H8WWC2
names: Subunit
messages: Homodimer.

1136231:CORT 0H01360
gene id: 1136231:CORT_0H01360
uniprot id: H8XB01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0G00850
gene id: 1136231:CORT_0G00850
uniprot id: H8X9V6
names: Function
names: Similarity
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.

1136231:CORT 0E01190
gene id: 1136231:CORT_0E01190
uniprot id: H8X6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

1136231:CORT 0B00340
gene id: 1136231:CORT_0B00340
uniprot id: H8WZ89
names: Subcellular Location Annotation
messages: nuclear pore complex

1136231:CORT 0D05240
gene id: 1136231:CORT_0D05240
uniprot id: H8X6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1136231:CORT 0B01450
gene id: 1136231:CORT_0B01450
uniprot id: H8WZJ6
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1136231:CORT 0A03970
gene id: 1136231:CORT_0A03970
uniprot id: H8WWG1
names: Similarity
messages: Belongs to the SF3A2 family.

1136231:CORT 0C04310
gene id: 1136231:CORT_0C04310
uniprot id: H8X416
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

1136231:CORT 0A03200
gene id: 1136231:CORT_0A03200
uniprot id: H8WW84
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

1136231:CORT 0E00580
gene id: 1136231:CORT_0E00580
uniprot id: H8X6N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

1136231:CORT 0B08260
gene id: 1136231:CORT_0B08260
uniprot id: H8X1X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1136231:CORT 0C04250
gene id: 1136231:CORT_0C04250
uniprot id: H8X410
names: Function
messages: Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.

1136231:CORT 0A08750
gene id: 1136231:CORT_0A08750
uniprot id: H8WYE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

1136231:CORT 0D02550
gene id: 1136231:CORT_0D02550
uniprot id: H8X508
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0E05390
gene id: 1136231:CORT_0E05390
uniprot id: H8X825
names: Similarity
messages: Belongs to the RPAP1 family.

1136231:CORT 0A08920
gene id: 1136231:CORT_0A08920
uniprot id: H8WYG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

1136231:CORT 0F02430
gene id: 1136231:CORT_0F02430
uniprot id: H8X8J3
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0C03940
gene id: 1136231:CORT_0C03940
uniprot id: H8X3Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

1136231:CORT 0F04100
gene id: 1136231:CORT_0F04100
uniprot id: H8X9G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

1136231:CORT 0B07870
gene id: 1136231:CORT_0B07870
uniprot id: H8X1T7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1136231:CORT 0B11320
gene id: 1136231:CORT_0B11320
uniprot id: H8X2A9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1136231:CORT 0G03540
gene id: 1136231:CORT_0G03540
uniprot id: H8XA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1136231:CORT 0A06860
gene id: 1136231:CORT_0A06860
uniprot id: H8WWT1
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

1136231:CORT 0A06590
gene id: 1136231:CORT_0A06590
uniprot id: H8WWQ6
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

1136231:CORT 0B09540
gene id: 1136231:CORT_0B09540
uniprot id: H8X0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting. Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer. Interacts with the chloride channel protein GEF1.

1136231:CORT 0A07080
gene id: 1136231:CORT_0A07080
uniprot id: H8WWV3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

1136231:CORT 0E02020
gene id: 1136231:CORT_0E02020
uniprot id: H8X7K6
names: Similarity
messages: Belongs to the calreticulin family.

1136231:CORT 0H01560
gene id: 1136231:CORT_0H01560
uniprot id: H8XB21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

1136231:CORT 0B07370
gene id: 1136231:CORT_0B07370
uniprot id: H8X1N8
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1136231:CORT 0E00880
gene id: 1136231:CORT_0E00880
uniprot id: H8X6R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0H00630
gene id: 1136231:CORT_0H00630
uniprot id: H8XBJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Membrane

1136231:CORT 0C04950
gene id: 1136231:CORT_0C04950
uniprot id: H8X309
names: Similarity
messages: Belongs to the UPP synthase family.

1136231:CORT 0B08420
gene id: 1136231:CORT_0B08420
uniprot id: H8X036
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

1136231:CORT 0C05450
gene id: 1136231:CORT_0C05450
uniprot id: H8X359
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

1136231:CORT 0B07760
gene id: 1136231:CORT_0B07760
uniprot id: H8X1S6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B11380
gene id: 1136231:CORT_0B11380
uniprot id: H8X2B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

1136231:CORT 0E01590
gene id: 1136231:CORT_0E01590
uniprot id: H8X7G3
names: Similarity
messages: Belongs to the peptidase M20A family.

1136231:CORT 0B04740
gene id: 1136231:CORT_0B04740
uniprot id: H8X1E2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B08290
gene id: 1136231:CORT_0B08290
uniprot id: H8X1X8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1136231:CORT 0D00750
gene id: 1136231:CORT_0D00750
uniprot id: H8X4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG7 family.
messages: Mitochondrion

1136231:CORT 0B01340
gene id: 1136231:CORT_0B01340
uniprot id: H8WZI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

1136231:CORT 0F04060
gene id: 1136231:CORT_0F04060
uniprot id: H8X9G4
names: Similarity
messages: Belongs to the SUN family.

1136231:CORT 0C06420
gene id: 1136231:CORT_0C06420
uniprot id: H8X464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1136231:CORT 0C04450
gene id: 1136231:CORT_0C04450
uniprot id: H8X2V8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0F00810
gene id: 1136231:CORT_0F00810
uniprot id: H8X911
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

1136231:CORT 0G00150
gene id: 1136231:CORT_0G00150
uniprot id: H8X9P0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1136231:CORT 0A05550
gene id: 1136231:CORT_0A05550
uniprot id: H8WXZ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC).

1136231:CORT 0B09500
gene id: 1136231:CORT_0B09500
uniprot id: H8X0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1136231:CORT 0G03770
gene id: 1136231:CORT_0G03770
uniprot id: H8XA76
names: Similarity
messages: Belongs to the amidase family.

1136231:CORT 0B00360
gene id: 1136231:CORT_0B00360
uniprot id: H8WZ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1136231:CORT 0C06590
gene id: 1136231:CORT_0C06590
uniprot id: H8X480
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1136231:CORT 0H00310
gene id: 1136231:CORT_0H00310
uniprot id: H8XBG1
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A07030
gene id: 1136231:CORT_0A07030
uniprot id: H8WWU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

1136231:CORT 0B05970
gene id: 1136231:CORT_0B05970
uniprot id: H8WZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

1136231:CORT 0A12880
gene id: 1136231:CORT_0A12880
uniprot id: H8WZ39
names: Similarity
messages: Belongs to the R-transferase family.

1136231:CORT 0A11180
gene id: 1136231:CORT_0A11180
uniprot id: H8WXJ7
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Nucleus

1136231:CORT 0G00410
gene id: 1136231:CORT_0G00410
uniprot id: H8X9R5
names: Similarity
messages: Belongs to the Rho GDI family.

1136231:CORT 0G04370
gene id: 1136231:CORT_0G04370
uniprot id: H8XAD7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1136231:CORT 0D04530
gene id: 1136231:CORT_0D04530
uniprot id: H8X645
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GMC oxidoreductase family.
messages: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.
messages: Peroxisome matrix

1136231:CORT 0D01300
gene id: 1136231:CORT_0D01300
uniprot id: H8X4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

1136231:CORT 0D02350
gene id: 1136231:CORT_0D02350
uniprot id: H8X4Z0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family.
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

1136231:CORT 0A13060
gene id: 1136231:CORT_0A13060
uniprot id: H8WXL6
names: Similarity
messages: Belongs to the RRN3 family.

1136231:CORT 0H00650
gene id: 1136231:CORT_0H00650
uniprot id: H8XBJ4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C02970
gene id: 1136231:CORT_0C02970
uniprot id: H8X3N5
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1136231:CORT 0B08760
gene id: 1136231:CORT_0B08760
uniprot id: H8X068
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

1136231:CORT 0C07320
gene id: 1136231:CORT_0C07320
uniprot id: H8X4F0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1136231:CORT 0G01660
gene id: 1136231:CORT_0G01660
uniprot id: H8XAK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

1136231:CORT 0B03890
gene id: 1136231:CORT_0B03890
uniprot id: H8X157
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0C02940
gene id: 1136231:CORT_0C02940
uniprot id: H8X3N2
names: Similarity
messages: Belongs to the PPase family.

1136231:CORT 0E03850
gene id: 1136231:CORT_0E03850
uniprot id: H8X744
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
messages: Vacuole lumen

1136231:CORT 0A07450
gene id: 1136231:CORT_0A07450
uniprot id: H8WWZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1136231:CORT 0A11350
gene id: 1136231:CORT_0A11350
uniprot id: H8WXL4
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B09370
gene id: 1136231:CORT_0B09370
uniprot id: H8X0C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1136231:CORT 0A11110
gene id: 1136231:CORT_0A11110
uniprot id: H8WXJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1136231:CORT 0F02730
gene id: 1136231:CORT_0F02730
uniprot id: H8X8M2
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

1136231:CORT 0B08030
gene id: 1136231:CORT_0B08030
uniprot id: H8X1V2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1136231:CORT 0A04080
gene id: 1136231:CORT_0A04080
uniprot id: H8WWH2
names: Similarity
messages: Belongs to the peptidase S8 family.

1136231:CORT 0B03160
gene id: 1136231:CORT_0B03160
uniprot id: H8X0Y7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D03480
gene id: 1136231:CORT_0D03480
uniprot id: H8X597
names: Similarity
messages: Belongs to the SAPS family.

1136231:CORT 0E00510
gene id: 1136231:CORT_0E00510
uniprot id: H8X6N0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D04860
gene id: 1136231:CORT_0D04860
uniprot id: H8X678
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1136231:CORT 0C06140
gene id: 1136231:CORT_0C06140
uniprot id: H8X435
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase.
messages: Mitochondrion inner membrane

1136231:CORT 0C04610
gene id: 1136231:CORT_0C04610
uniprot id: H8X2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm
messages: nucleolus

1136231:CORT 0D04120
gene id: 1136231:CORT_0D04120
uniprot id: H8X604
names: Similarity
messages: Belongs to the TMEM14 family.

1136231:CORT 0D06850
gene id: 1136231:CORT_0D06850
uniprot id: H8X5R0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1136231:CORT 0A13200
gene id: 1136231:CORT_0A13200
uniprot id: H8WXN0
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.

1136231:CORT 0D01360
gene id: 1136231:CORT_0D01360
uniprot id: H8X4P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

1136231:CORT 0E05280
gene id: 1136231:CORT_0E05280
uniprot id: H8X814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

1136231:CORT 0E03040
gene id: 1136231:CORT_0E03040
uniprot id: H8X7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

1136231:CORT 0B02630
gene id: 1136231:CORT_0B02630
uniprot id: H8X0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

1136231:CORT 0C06940
gene id: 1136231:CORT_0C06940
uniprot id: H8X4B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0B01760
gene id: 1136231:CORT_0B01760
uniprot id: H8X0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0D04250
gene id: 1136231:CORT_0D04250
uniprot id: H8X617
names: Similarity
messages: Belongs to the WrbA family.

1136231:CORT 0G04460
gene id: 1136231:CORT_0G04460
uniprot id: H8XAE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0B08070
gene id: 1136231:CORT_0B08070
uniprot id: H8X1V6
names: Similarity
messages: Belongs to the cytochrome b5 family.

1136231:CORT 0B10490
gene id: 1136231:CORT_0B10490
uniprot id: H8X230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Mitochondrion

1136231:CORT 0D01150
gene id: 1136231:CORT_0D01150
uniprot id: H8X4M1
names: Similarity
messages: Belongs to the TOG/XMAP215 family.

1136231:CORT 0H00530
gene id: 1136231:CORT_0H00530
uniprot id: H8XBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0H02540
gene id: 1136231:CORT_0H02540
uniprot id: H8XBB5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D01320
gene id: 1136231:CORT_0D01320
uniprot id: H8X4N8
names: Similarity
messages: Belongs to the actin family.

1136231:CORT 0D06270
gene id: 1136231:CORT_0D06270
uniprot id: H8X5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

1136231:CORT 0A00660
gene id: 1136231:CORT_0A00660
uniprot id: H8WVI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low.
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Nucleus
messages: telomere

1136231:CORT 0E04430
gene id: 1136231:CORT_0E04430
uniprot id: H8X7A0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1136231:CORT 0F03210
gene id: 1136231:CORT_0F03210
uniprot id: H8X8S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

1136231:CORT 0B01980
gene id: 1136231:CORT_0B01980
uniprot id: H8X0M7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

1136231:CORT 0E05700
gene id: 1136231:CORT_0E05700
uniprot id: H8X855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1136231:CORT 0B05160
gene id: 1136231:CORT_0B05160
uniprot id: H8WZM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

1136231:CORT 0B11220
gene id: 1136231:CORT_0B11220
uniprot id: H8X299
names: Similarity
messages: Belongs to the MBF1 family.

1136231:CORT 0A00790
gene id: 1136231:CORT_0A00790
uniprot id: H8WVJ7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1136231:CORT 0B07600
gene id: 1136231:CORT_0B07600
uniprot id: H8X1R1
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1136231:CORT 0B00490
gene id: 1136231:CORT_0B00490
uniprot id: H8WZA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1136231:CORT 0D01560
gene id: 1136231:CORT_0D01560
uniprot id: H8X4R2
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B03840
gene id: 1136231:CORT_0B03840
uniprot id: H8X152
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0G02620
gene id: 1136231:CORT_0G02620
uniprot id: H8XAU2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1136231:CORT 0A08740
gene id: 1136231:CORT_0A08740
uniprot id: H8WYE3
names: Similarity
messages: Belongs to the OSBP family.

1136231:CORT 0B11310
gene id: 1136231:CORT_0B11310
uniprot id: H8X2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS27 family.
messages: Endosome membrane
messages: Membrane

1136231:CORT 0E00200
gene id: 1136231:CORT_0E00200
uniprot id: H8X6K0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D01000
gene id: 1136231:CORT_0D01000
uniprot id: H8X4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

1136231:CORT 0D04040
gene id: 1136231:CORT_0D04040
uniprot id: H8X5Z6
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

1136231:CORT 0G00610
gene id: 1136231:CORT_0G00610
uniprot id: H8X9T4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1136231:CORT 0B10790
gene id: 1136231:CORT_0B10790
uniprot id: H8X259
names: Similarity
messages: Belongs to the VPS29 family.

1136231:CORT 0F02550
gene id: 1136231:CORT_0F02550
uniprot id: H8X8K4
names: Similarity
messages: Belongs to the BMT family.

1136231:CORT 0C00310
gene id: 1136231:CORT_0C00310
uniprot id: H8X3D7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1136231:CORT 0A02290
gene id: 1136231:CORT_0A02290
uniprot id: H8WVZ6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C05120
gene id: 1136231:CORT_0C05120
uniprot id: H8X326
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G01160
gene id: 1136231:CORT_0G01160
uniprot id: H8XAF4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E04830
gene id: 1136231:CORT_0E04830
uniprot id: H8X7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

1136231:CORT 0B05630
gene id: 1136231:CORT_0B05630
uniprot id: H8WZS6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0G00470
gene id: 1136231:CORT_0G00470
uniprot id: H8X9S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1136231:CORT 0B07610
gene id: 1136231:CORT_0B07610
uniprot id: H8X1R2
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B07540
gene id: 1136231:CORT_0B07540
uniprot id: H8X1Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GON7 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Nucleus

1136231:CORT 0A03390
gene id: 1136231:CORT_0A03390
uniprot id: H8WWA3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D06940
gene id: 1136231:CORT_0D06940
uniprot id: H8X5R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EST3 family.
messages: Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase.
messages: Nucleus
messages: telomere

1136231:CORT 0A03160
gene id: 1136231:CORT_0A03160
uniprot id: H8WW80
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1136231:CORT 0C06340
gene id: 1136231:CORT_0C06340
uniprot id: H8X456
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

1136231:CORT 0E05370
gene id: 1136231:CORT_0E05370
uniprot id: H8X823
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

1136231:CORT 0A08800
gene id: 1136231:CORT_0A08800
uniprot id: H8WYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

1136231:CORT 0A12200
gene id: 1136231:CORT_0A12200
uniprot id: H8WYX3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1136231:CORT 0B01580
gene id: 1136231:CORT_0B01580
uniprot id: H8WZK9
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

1136231:CORT 0E01360
gene id: 1136231:CORT_0E01360
uniprot id: H8X6W3
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1136231:CORT 0A09580
gene id: 1136231:CORT_0A09580
uniprot id: H8WYM8
names: Function
names: Similarity
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.

1136231:CORT 0A02220
gene id: 1136231:CORT_0A02220
uniprot id: H8WVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP25 family.
messages: Mitochondrial mRNA stabilization factor.
messages: Mitochondrion inner membrane

1136231:CORT 0D00600
gene id: 1136231:CORT_0D00600
uniprot id: H8X4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunit 4 family.
messages: centrosome
messages: sarcomere
messages: stress fiber

1136231:CORT 0C02280
gene id: 1136231:CORT_0C02280
uniprot id: H8X2Q7
names: Similarity
messages: Belongs to the group II decarboxylase family.

1136231:CORT 0D06160
gene id: 1136231:CORT_0D06160
uniprot id: H8X5J6
names: Similarity
messages: Belongs to the hexokinase family.

1136231:CORT 0H00430
gene id: 1136231:CORT_0H00430
uniprot id: H8XBH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Mitochondrion inner membrane

1136231:CORT 0A02120
gene id: 1136231:CORT_0A02120
uniprot id: H8WVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0B00160
gene id: 1136231:CORT_0B00160
uniprot id: H8WZ71
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

1136231:CORT 0B04010
gene id: 1136231:CORT_0B04010
uniprot id: H8X169
names: Similarity
messages: Belongs to the BMT family.

1136231:CORT 0E05190
gene id: 1136231:CORT_0E05190
uniprot id: H8X805
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

1136231:CORT 0H00300
gene id: 1136231:CORT_0H00300
uniprot id: H8XBG0
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1136231:CORT 0A04840
gene id: 1136231:CORT_0A04840
uniprot id: H8WXS5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A08360
gene id: 1136231:CORT_0A08360
uniprot id: H8WYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Mitochondrion inner membrane

1136231:CORT 0A11980
gene id: 1136231:CORT_0A11980
uniprot id: H8WYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

1136231:CORT 0C04750
gene id: 1136231:CORT_0C04750
uniprot id: H8X2Y9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E03600
gene id: 1136231:CORT_0E03600
uniprot id: H8X720
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1136231:CORT 0D02640
gene id: 1136231:CORT_0D02640
uniprot id: H8X516
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

1136231:CORT 0B06410
gene id: 1136231:CORT_0B06410
uniprot id: H8X005
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

1136231:CORT 0G01910
gene id: 1136231:CORT_0G01910
uniprot id: H8XAM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

1136231:CORT 0G01400
gene id: 1136231:CORT_0G01400
uniprot id: H8XAH8
names: Cofactor
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.

1136231:CORT 0C01110
gene id: 1136231:CORT_0C01110
uniprot id: H8X2E1
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0E03210
gene id: 1136231:CORT_0E03210
uniprot id: H8X6Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

1136231:CORT 0B07310
gene id: 1136231:CORT_0B07310
uniprot id: H8X1N3
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

1136231:CORT 0A00480
gene id: 1136231:CORT_0A00480
uniprot id: H8WVG9
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1136231:CORT 0C05590
gene id: 1136231:CORT_0C05590
uniprot id: H8X373
names: Similarity
messages: Belongs to the TCF25 family.

1136231:CORT 0E05620
gene id: 1136231:CORT_0E05620
uniprot id: H8X848
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

1136231:CORT 0A09210
gene id: 1136231:CORT_0A09210
uniprot id: H8WYJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.

1136231:CORT 0G00780
gene id: 1136231:CORT_0G00780
uniprot id: H8X9V0
names: Similarity
messages: Belongs to the IML2 family.

1136231:CORT 0D04500
gene id: 1136231:CORT_0D04500
uniprot id: H8X642
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

1136231:CORT 0H02010
gene id: 1136231:CORT_0H02010
uniprot id: H8XB65
names: Similarity
messages: Belongs to the SLA2 family.

1136231:CORT 0C03530
gene id: 1136231:CORT_0C03530
uniprot id: H8X3T9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

1136231:CORT 0G00620
gene id: 1136231:CORT_0G00620
uniprot id: H8X9T5
names: Similarity
messages: Belongs to the patched family.

1136231:CORT 0B10080
gene id: 1136231:CORT_0B10080
uniprot id: H8X1Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1136231:CORT 0C05070
gene id: 1136231:CORT_0C05070
uniprot id: H8X321
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

1136231:CORT 0A06600
gene id: 1136231:CORT_0A06600
uniprot id: H8WWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBP4 family.
messages: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.
messages: Mitochondrion inner membrane

1136231:CORT 0A04400
gene id: 1136231:CORT_0A04400
uniprot id: H8WWK4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D03450
gene id: 1136231:CORT_0D03450
uniprot id: H8X594
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Homooctamer.

1136231:CORT 0A01040
gene id: 1136231:CORT_0A01040
uniprot id: H8WVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane

1136231:CORT 0H01990
gene id: 1136231:CORT_0H01990
uniprot id: H8XB63
names: Similarity
messages: Belongs to the TAF11 family.

1136231:CORT 0A10940
gene id: 1136231:CORT_0A10940
uniprot id: H8WXH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0G04350
gene id: 1136231:CORT_0G04350
uniprot id: H8XAD5
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1136231:CORT 0B03340
gene id: 1136231:CORT_0B03340
uniprot id: H8X104
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

1136231:CORT 0F04270
gene id: 1136231:CORT_0F04270
uniprot id: H8X9I5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F00430
gene id: 1136231:CORT_0F00430
uniprot id: H8X8X4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A06610
gene id: 1136231:CORT_0A06610
uniprot id: H8WWQ8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H01680
gene id: 1136231:CORT_0H01680
uniprot id: H8XB33
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0C04100
gene id: 1136231:CORT_0C04100
uniprot id: H8X3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

1136231:CORT 0A13330
gene id: 1136231:CORT_0A13330
uniprot id: H8WXP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0A01030
gene id: 1136231:CORT_0A01030
uniprot id: H8WVM2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136231:CORT 0B06620
gene id: 1136231:CORT_0B06620
uniprot id: H8X025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1136231:CORT 0A12910
gene id: 1136231:CORT_0A12910
uniprot id: H8WZ42
names: Similarity
messages: Belongs to the PRP18 family.

1136231:CORT 0C04890
gene id: 1136231:CORT_0C04890
uniprot id: H8X303
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

1136231:CORT 0C07190
gene id: 1136231:CORT_0C07190
uniprot id: H8X4D8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Heterodimer with ALG13 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus membrane

1136231:CORT 0F03630
gene id: 1136231:CORT_0F03630
uniprot id: H8X9C0
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1136231:CORT 0B05260
gene id: 1136231:CORT_0B05260
uniprot id: H8WZN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily.
messages: Homodimer.
messages: Plays an important role in the cellular response to the nitrogen source.

1136231:CORT 0A12090
gene id: 1136231:CORT_0A12090
uniprot id: H8WYW2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0A06400
gene id: 1136231:CORT_0A06400
uniprot id: H8WWN7
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

1136231:CORT 0A05750
gene id: 1136231:CORT_0A05750
uniprot id: H8WY15
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0F02630
gene id: 1136231:CORT_0F02630
uniprot id: H8X8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

1136231:CORT 0E03340
gene id: 1136231:CORT_0E03340
uniprot id: H8X6Z4
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

1136231:CORT 0D01530
gene id: 1136231:CORT_0D01530
uniprot id: H8X4Q9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1136231:CORT 0A12460
gene id: 1136231:CORT_0A12460
uniprot id: H8WYZ9
names: Similarity
messages: Belongs to the allantoicase family.

1136231:CORT 0B09800
gene id: 1136231:CORT_0B09800
uniprot id: H8X0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B05920
gene id: 1136231:CORT_0B05920
uniprot id: H8WZV6
names: Similarity
messages: Belongs to the ADIP family.

1136231:CORT 0B00690
gene id: 1136231:CORT_0B00690
uniprot id: H8WZC2
names: Similarity
messages: Belongs to the TPA1 family.

1136231:CORT 0D00170
gene id: 1136231:CORT_0D00170
uniprot id: H8X5V2
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1136231:CORT 0A04530
gene id: 1136231:CORT_0A04530
uniprot id: H8WWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0B05090
gene id: 1136231:CORT_0B05090
uniprot id: H8WZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0B07080
gene id: 1136231:CORT_0B07080
uniprot id: H8X1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

1136231:CORT 0B03970
gene id: 1136231:CORT_0B03970
uniprot id: H8X165
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0A01810
gene id: 1136231:CORT_0A01810
uniprot id: H8WVU8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1136231:CORT 0D00410
gene id: 1136231:CORT_0D00410
uniprot id: H8X5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS4/SLD5 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

1136231:CORT 0A05890
gene id: 1136231:CORT_0A05890
uniprot id: H8WY29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD2 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1136231:CORT 0E02630
gene id: 1136231:CORT_0E02630
uniprot id: H8X7R4
names: Cofactor
messages: Divalent metal ions. Mg(2+) is the most effective.

1136231:CORT 0B10190
gene id: 1136231:CORT_0B10190
uniprot id: H8X202
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0G04040
gene id: 1136231:CORT_0G04040
uniprot id: H8XAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0B07530
gene id: 1136231:CORT_0B07530
uniprot id: H8X1Q4
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1136231:CORT 0F01810
gene id: 1136231:CORT_0F01810
uniprot id: H8X8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

1136231:CORT 0C00250
gene id: 1136231:CORT_0C00250
uniprot id: H8X3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

1136231:CORT 0A05410
gene id: 1136231:CORT_0A05410
uniprot id: H8WXY2
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

1136231:CORT 0E04700
gene id: 1136231:CORT_0E04700
uniprot id: H8X7C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.
messages: Membrane

1136231:CORT 0A04870
gene id: 1136231:CORT_0A04870
uniprot id: H8WXS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GET2 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

1136231:CORT 0E01290
gene id: 1136231:CORT_0E01290
uniprot id: H8X6V6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

1136231:CORT 0B01180
gene id: 1136231:CORT_0B01180
uniprot id: H8WZH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1136231:CORT 0G01310
gene id: 1136231:CORT_0G01310
uniprot id: H8XAG9
names: Similarity
messages: Belongs to the lysophospholipase family.

1136231:CORT 0G03020
gene id: 1136231:CORT_0G03020
uniprot id: H8XA03
names: Similarity
messages: Belongs to the Tango6 family.

1136231:CORT 0A00730
gene id: 1136231:CORT_0A00730
uniprot id: H8WVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0B02730
gene id: 1136231:CORT_0B02730
uniprot id: H8X0U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: centromere

1136231:CORT 0A01610
gene id: 1136231:CORT_0A01610
uniprot id: H8WVS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription. SAGA is required for recruitment of the basal transcription machinery. SLIK is proposed to have partly overlapping functions with SAGA.
messages: Nucleus

1136231:CORT 0E00550
gene id: 1136231:CORT_0E00550
uniprot id: H8X6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

1136231:CORT 0A00250
gene id: 1136231:CORT_0A00250
uniprot id: H8WVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0E06520
gene id: 1136231:CORT_0E06520
uniprot id: H8X7D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

1136231:CORT 0A04150
gene id: 1136231:CORT_0A04150
uniprot id: H8WWH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

1136231:CORT 0D00270
gene id: 1136231:CORT_0D00270
uniprot id: H8X5W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

1136231:CORT 0B02880
gene id: 1136231:CORT_0B02880
uniprot id: H8X0W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0G03410
gene id: 1136231:CORT_0G03410
uniprot id: H8XA40
names: Similarity
messages: Belongs to the oligoribonuclease family.

1136231:CORT 0A02720
gene id: 1136231:CORT_0A02720
uniprot id: H8WW38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0B03080
gene id: 1136231:CORT_0B03080
uniprot id: H8X0Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1136231:CORT 0G00420
gene id: 1136231:CORT_0G00420
uniprot id: H8X9R6
names: Similarity
messages: Belongs to the Rho GDI family.

1136231:CORT 0A01980
gene id: 1136231:CORT_0A01980
uniprot id: H8WVW5
names: Similarity
messages: Belongs to the AAA ATPase family.

1136231:CORT 0A02960
gene id: 1136231:CORT_0A02960
uniprot id: H8WW61
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

1136231:CORT 0G03620
gene id: 1136231:CORT_0G03620
uniprot id: H8XA61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1136231:CORT 0G01090
gene id: 1136231:CORT_0G01090
uniprot id: H8X9Y0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0H02290
gene id: 1136231:CORT_0H02290
uniprot id: H8XB90
names: Similarity
messages: Belongs to the actin family.

1136231:CORT 0E03760
gene id: 1136231:CORT_0E03760
uniprot id: H8X736
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

1136231:CORT 0B09670
gene id: 1136231:CORT_0B09670
uniprot id: H8X0F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1136231:CORT 0C02050
gene id: 1136231:CORT_0C02050
uniprot id: H8X2N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.

1136231:CORT 0A01390
gene id: 1136231:CORT_0A01390
uniprot id: H8WVQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Cytoplasm
messages: Membrane

1136231:CORT 0A08410
gene id: 1136231:CORT_0A08410
uniprot id: H8WYB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

1136231:CORT 0A04190
gene id: 1136231:CORT_0A04190
uniprot id: H8WWI3
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

1136231:CORT 0A02870
gene id: 1136231:CORT_0A02870
uniprot id: H8WW53
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

1136231:CORT 0G00490
gene id: 1136231:CORT_0G00490
uniprot id: H8X9S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1136231:CORT 0A07220
gene id: 1136231:CORT_0A07220
uniprot id: H8WWW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136231:CORT 0A05510
gene id: 1136231:CORT_0A05510
uniprot id: H8WXZ1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

1136231:CORT 0A10410
gene id: 1136231:CORT_0A10410
uniprot id: H8WXC1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

1136231:CORT 0G01900
gene id: 1136231:CORT_0G01900
uniprot id: H8XAM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B01670
gene id: 1136231:CORT_0B01670
uniprot id: H8X0J7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1136231:CORT 0F00480
gene id: 1136231:CORT_0F00480
uniprot id: H8X8X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

1136231:CORT 0G02140
gene id: 1136231:CORT_0G02140
uniprot id: H8XAP5
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

1136231:CORT 0B06530
gene id: 1136231:CORT_0B06530
uniprot id: H8X017
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

1136231:CORT 0C00630
gene id: 1136231:CORT_0C00630
uniprot id: H8X3G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B00370
gene id: 1136231:CORT_0B00370
uniprot id: H8WZ92
names: Similarity
messages: Belongs to the APC5 family.

1136231:CORT 0D04880
gene id: 1136231:CORT_0D04880
uniprot id: H8X680
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Plays a role in the regulation of filamentous growth and chronological longevity.
messages: Homodimer.
messages: Preautophagosomal structure

1136231:CORT 0B10600
gene id: 1136231:CORT_0B10600
uniprot id: H8X240
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1136231:CORT 0A00760
gene id: 1136231:CORT_0A00760
uniprot id: H8WVJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

1136231:CORT 0H00890
gene id: 1136231:CORT_0H00890
uniprot id: H8XBL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YAE1 family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0D04840
gene id: 1136231:CORT_0D04840
uniprot id: H8X676
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

1136231:CORT 0A01140
gene id: 1136231:CORT_0A01140
uniprot id: H8WVN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Mitochondrion matrix

1136231:CORT 0B09040
gene id: 1136231:CORT_0B09040
uniprot id: H8X096
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

1136231:CORT 0C01250
gene id: 1136231:CORT_0C01250
uniprot id: H8X2F5
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

1136231:CORT 0B07470
gene id: 1136231:CORT_0B07470
uniprot id: H8X1P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

1136231:CORT 0D03350
gene id: 1136231:CORT_0D03350
uniprot id: H8X585
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

1136231:CORT 0B00780
gene id: 1136231:CORT_0B00780
uniprot id: H8WZD1
names: Similarity
messages: Belongs to the complex I LYR family.

1136231:CORT 0D06830
gene id: 1136231:CORT_0D06830
uniprot id: H8X5Q8
names: Similarity
messages: Belongs to the IST1 family.

1136231:CORT 0E05310
gene id: 1136231:CORT_0E05310
uniprot id: H8X817
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPT35 family.
messages: Endosome membrane
messages: Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
messages: Vacuole membrane

1136231:CORT 0A01320
gene id: 1136231:CORT_0A01320
uniprot id: H8WVQ0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D07490
gene id: 1136231:CORT_0D07490
uniprot id: H8X6H1
names: Similarity
messages: Belongs to the peptidase C48 family.

1136231:CORT 0H02350
gene id: 1136231:CORT_0H02350
uniprot id: H8XB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0C05220
gene id: 1136231:CORT_0C05220
uniprot id: H8X336
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1136231:CORT 0G02910
gene id: 1136231:CORT_0G02910
uniprot id: H8X9Z2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1136231:CORT 0B10380
gene id: 1136231:CORT_0B10380
uniprot id: H8X219
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0A05450
gene id: 1136231:CORT_0A05450
uniprot id: H8WXY5
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

1136231:CORT 0B08480
gene id: 1136231:CORT_0B08480
uniprot id: H8X041
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A06130
gene id: 1136231:CORT_0A06130
uniprot id: H8WY53
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

1136231:CORT 0G01210
gene id: 1136231:CORT_0G01210
uniprot id: H8XAF9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

1136231:CORT 0B10810
gene id: 1136231:CORT_0B10810
uniprot id: H8X261
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0E05520
gene id: 1136231:CORT_0E05520
uniprot id: H8X838
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC4 family.
messages: May be involved in a process influencing telomere capping.
messages: Nucleus

1136231:CORT 0C00510
gene id: 1136231:CORT_0C00510
uniprot id: H8X3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0B09770
gene id: 1136231:CORT_0B09770
uniprot id: H8X0G9
names: Similarity
messages: Belongs to the actin family.

1136231:CORT 0A02630
gene id: 1136231:CORT_0A02630
uniprot id: H8WW30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

1136231:CORT 0C03870
gene id: 1136231:CORT_0C03870
uniprot id: H8X3X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0A05730
gene id: 1136231:CORT_0A05730
uniprot id: H8WY13
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0A01170
gene id: 1136231:CORT_0A01170
uniprot id: H8WVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1136231:CORT 0D05790
gene id: 1136231:CORT_0D05790
uniprot id: H8X5G1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1136231:CORT 0B08860
gene id: 1136231:CORT_0B08860
uniprot id: H8X078
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0H02690
gene id: 1136231:CORT_0H02690
uniprot id: H8XBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: nucleolus

1136231:CORT 0B04480
gene id: 1136231:CORT_0B04480
uniprot id: H8X1B6
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1136231:CORT 0A04500
gene id: 1136231:CORT_0A04500
uniprot id: H8WWL4
names: Similarity
messages: Belongs to the thymidylate kinase family.

1136231:CORT 0F02670
gene id: 1136231:CORT_0F02670
uniprot id: H8X8L6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E06130
gene id: 1136231:CORT_0E06130
uniprot id: H8X896
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1136231:CORT 0G00990
gene id: 1136231:CORT_0G00990
uniprot id: H8X9X0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

1136231:CORT 0D06590
gene id: 1136231:CORT_0D06590
uniprot id: H8X5N5
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

1136231:CORT 0B05230
gene id: 1136231:CORT_0B05230
uniprot id: H8WZN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0H01480
gene id: 1136231:CORT_0H01480
uniprot id: H8XB13
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1136231:CORT 0G01080
gene id: 1136231:CORT_0G01080
uniprot id: H8X9X9
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1136231:CORT 0A03830
gene id: 1136231:CORT_0A03830
uniprot id: H8WWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1136231:CORT 0F00410
gene id: 1136231:CORT_0F00410
uniprot id: H8X8X2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A04000
gene id: 1136231:CORT_0A04000
uniprot id: H8WWG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.

1136231:CORT 0A03450
gene id: 1136231:CORT_0A03450
uniprot id: H8WWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

1136231:CORT 0A00350
gene id: 1136231:CORT_0A00350
uniprot id: H8WVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1136231:CORT 0A01890
gene id: 1136231:CORT_0A01890
uniprot id: H8WVV6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B05510
gene id: 1136231:CORT_0B05510
uniprot id: H8WZR4
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

1136231:CORT 0B03400
gene id: 1136231:CORT_0B03400
uniprot id: H8X109
names: Similarity
messages: Belongs to the polyprenol kinase family.

1136231:CORT 0D06880
gene id: 1136231:CORT_0D06880
uniprot id: H8X5R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

1136231:CORT 0G02970
gene id: 1136231:CORT_0G02970
uniprot id: H8X9Z8
names: Similarity
messages: Belongs to the TBCC family.

1136231:CORT 0B10960
gene id: 1136231:CORT_0B10960
uniprot id: H8X273
names: Similarity
messages: Belongs to the ZPR1 family.

1136231:CORT 0B06470
gene id: 1136231:CORT_0B06470
uniprot id: H8X011
names: Function
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0C05010
gene id: 1136231:CORT_0C05010
uniprot id: H8X315
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1136231:CORT 0A11760
gene id: 1136231:CORT_0A11760
uniprot id: H8WYS9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F02460
gene id: 1136231:CORT_0F02460
uniprot id: H8X8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

1136231:CORT 0C06350
gene id: 1136231:CORT_0C06350
uniprot id: H8X457
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0A11680
gene id: 1136231:CORT_0A11680
uniprot id: H8WYS1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H01250
gene id: 1136231:CORT_0H01250
uniprot id: H8XAZ3
names: Subcellular Location Annotation
messages: Mitochondrion

1136231:CORT 0D03370
gene id: 1136231:CORT_0D03370
uniprot id: H8X587
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A06030
gene id: 1136231:CORT_0A06030
uniprot id: H8WY43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

1136231:CORT 0C00330
gene id: 1136231:CORT_0C00330
uniprot id: H8X3D9
names: Similarity
messages: Belongs to the NAD kinase family.

1136231:CORT 0A07630
gene id: 1136231:CORT_0A07630
uniprot id: H8WX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0F01120
gene id: 1136231:CORT_0F01120
uniprot id: H8X941
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
messages: Vacuole lumen

1136231:CORT 0C02880
gene id: 1136231:CORT_0C02880
uniprot id: H8X3M6
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

1136231:CORT 0E01410
gene id: 1136231:CORT_0E01410
uniprot id: H8X6W8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A07010
gene id: 1136231:CORT_0A07010
uniprot id: H8WWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

1136231:CORT 0B06670
gene id: 1136231:CORT_0B06670
uniprot id: H8X1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSA3 family.
messages: Required for efficient biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1136231:CORT 0F02560
gene id: 1136231:CORT_0F02560
uniprot id: H8X8K5
names: Similarity
messages: Belongs to the BMT family.

1136231:CORT 0H01770
gene id: 1136231:CORT_0H01770
uniprot id: H8XB41
names: Similarity
messages: Belongs to the UPF0357 family.

1136231:CORT 0C06770
gene id: 1136231:CORT_0C06770
uniprot id: H8X497
names: Similarity
messages: Belongs to the CWC22 family.

1136231:CORT 0E02990
gene id: 1136231:CORT_0E02990
uniprot id: H8X7V2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C01590
gene id: 1136231:CORT_0C01590
uniprot id: H8X2I9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136231:CORT 0C03450
gene id: 1136231:CORT_0C03450
uniprot id: H8X3T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1136231:CORT 0B04830
gene id: 1136231:CORT_0B04830
uniprot id: H8X1F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NST1 family.
messages: Cytoplasm
messages: May act as a negative regulator of salt tolerance.

1136231:CORT 0D01770
gene id: 1136231:CORT_0D01770
uniprot id: H8X4T3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E01500
gene id: 1136231:CORT_0E01500
uniprot id: H8X7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0D03190
gene id: 1136231:CORT_0D03190
uniprot id: H8X570
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A11750
gene id: 1136231:CORT_0A11750
uniprot id: H8WYS8
names: Similarity
messages: Belongs to the UPF0507 family.

1136231:CORT 0H02420
gene id: 1136231:CORT_0H02420
uniprot id: H8XBA3
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

1136231:CORT 0C02710
gene id: 1136231:CORT_0C02710
uniprot id: H8X2U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

1136231:CORT 0B01330
gene id: 1136231:CORT_0B01330
uniprot id: H8WZI4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0E05220
gene id: 1136231:CORT_0E05220
uniprot id: H8X808
names: Similarity
messages: Belongs to the guanylate kinase family.

1136231:CORT 0B00500
gene id: 1136231:CORT_0B00500
uniprot id: H8WZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1.
messages: Nucleus

1136231:CORT 0C03210
gene id: 1136231:CORT_0C03210
uniprot id: H8X3Q8
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

1136231:CORT 0C05190
gene id: 1136231:CORT_0C05190
uniprot id: H8X333
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1136231:CORT 0A07880
gene id: 1136231:CORT_0A07880
uniprot id: H8WX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

1136231:CORT 0A09640
gene id: 1136231:CORT_0A09640
uniprot id: H8WYN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

1136231:CORT 0A09140
gene id: 1136231:CORT_0A09140
uniprot id: H8WYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0B01160
gene id: 1136231:CORT_0B01160
uniprot id: H8WZG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

1136231:CORT 0C07250
gene id: 1136231:CORT_0C07250
uniprot id: H8X4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0F04310
gene id: 1136231:CORT_0F04310
uniprot id: H8X9I9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0G01460
gene id: 1136231:CORT_0G01460
uniprot id: H8XAI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

1136231:CORT 0A07750
gene id: 1136231:CORT_0A07750
uniprot id: H8WX21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

1136231:CORT 0B09230
gene id: 1136231:CORT_0B09230
uniprot id: H8X0B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.
messages: Membrane

1136231:CORT 0G00330
gene id: 1136231:CORT_0G00330
uniprot id: H8X9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

1136231:CORT 0G04010
gene id: 1136231:CORT_0G04010
uniprot id: H8XAA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

1136231:CORT 0B00310
gene id: 1136231:CORT_0B00310
uniprot id: H8WZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0E02780
gene id: 1136231:CORT_0E02780
uniprot id: H8X7S9
names: Function
names: Similarity
messages: Belongs to the choline monooxygenase family.
messages: Catalyzes the first step of the osmoprotectant glycine betaine synthesis.

1136231:CORT 0B11090
gene id: 1136231:CORT_0B11090
uniprot id: H8X286
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

1136231:CORT 0E04340
gene id: 1136231:CORT_0E04340
uniprot id: H8X792
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1136231:CORT 0E01020
gene id: 1136231:CORT_0E01020
uniprot id: H8X6T0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

1136231:CORT 0A12580
gene id: 1136231:CORT_0A12580
uniprot id: H8WZ11
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B02300
gene id: 1136231:CORT_0B02300
uniprot id: H8X0Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family.
messages: cell wall

1136231:CORT 0A02590
gene id: 1136231:CORT_0A02590
uniprot id: H8WW26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Dom34-Hbs1 complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway (PubMed:20890290). In the Dom34-Hbs1 complex, dom34 recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel. Following ribosome-binding, the Dom34-Hbs1 complex promotes the disassembly of stalled ribosomes, followed by degradation of damaged mRNAs as part of the NGD pathway.
messages: Cytoplasm

1136231:CORT 0A01080
gene id: 1136231:CORT_0A01080
uniprot id: H8WVM7
names: Similarity
messages: Belongs to the pantothenate synthetase family.

1136231:CORT 0E03260
gene id: 1136231:CORT_0E03260
uniprot id: H8X6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0G02520
gene id: 1136231:CORT_0G02520
uniprot id: H8XAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

1136231:CORT 0A07900
gene id: 1136231:CORT_0A07900
uniprot id: H8WX36
names: Similarity
messages: Belongs to the peptidase C13 family.

1136231:CORT 0A11160
gene id: 1136231:CORT_0A11160
uniprot id: H8WXJ5
names: Similarity
messages: Belongs to the PITHD1 family.

1136231:CORT 0E05500
gene id: 1136231:CORT_0E05500
uniprot id: H8X836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

1136231:CORT 0A00720
gene id: 1136231:CORT_0A00720
uniprot id: H8WVJ0
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1136231:CORT 0F00720
gene id: 1136231:CORT_0F00720
uniprot id: H8X903
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

1136231:CORT 0A06570
gene id: 1136231:CORT_0A06570
uniprot id: H8WWQ4
names: Similarity
messages: Belongs to the enolase family.

1136231:CORT 0A07640
gene id: 1136231:CORT_0A07640
uniprot id: H8WX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ECO subfamily.
messages: Nucleus

1136231:CORT 0A13240
gene id: 1136231:CORT_0A13240
uniprot id: H8WXN4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B04410
gene id: 1136231:CORT_0B04410
uniprot id: H8X1A8
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

1136231:CORT 0C04970
gene id: 1136231:CORT_0C04970
uniprot id: H8X311
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1136231:CORT 0C02870
gene id: 1136231:CORT_0C02870
uniprot id: H8X3M5
names: Similarity
messages: Belongs to the MAD2 family.

1136231:CORT 0D05330
gene id: 1136231:CORT_0D05330
uniprot id: H8X6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

1136231:CORT 0F04640
gene id: 1136231:CORT_0F04640
uniprot id: H8X9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

1136231:CORT 0D07220
gene id: 1136231:CORT_0D07220
uniprot id: H8X6E4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1136231:CORT 0A03210
gene id: 1136231:CORT_0A03210
uniprot id: H8WW85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

1136231:CORT 0F00690
gene id: 1136231:CORT_0F00690
uniprot id: H8X900
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

1136231:CORT 0C05860
gene id: 1136231:CORT_0C05860
uniprot id: H8X399
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

1136231:CORT 0D05820
gene id: 1136231:CORT_0D05820
uniprot id: H8X5G4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

1136231:CORT 0F04180
gene id: 1136231:CORT_0F04180
uniprot id: H8X9H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAR5 family.
messages: Endoplasmic reticulum membrane
messages: Nucleus membrane
messages: Required for nuclear membrane fusion during karyogamy.

1136231:CORT 0C04860
gene id: 1136231:CORT_0C04860
uniprot id: H8X300
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1136231:CORT 0B01410
gene id: 1136231:CORT_0B01410
uniprot id: H8WZJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1136231:CORT 0G03960
gene id: 1136231:CORT_0G03960
uniprot id: H8XA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0A08630
gene id: 1136231:CORT_0A08630
uniprot id: H8WYD2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

1136231:CORT 0A11630
gene id: 1136231:CORT_0A11630
uniprot id: H8WYR6
names: Similarity
messages: Belongs to the RRP7 family.

1136231:CORT 0B10510
gene id: 1136231:CORT_0B10510
uniprot id: H8X232
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ISN1 family.
messages: Homotetramer.
messages: IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.

1136231:CORT 0D04080
gene id: 1136231:CORT_0D04080
uniprot id: H8X600
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136231:CORT 0B06540
gene id: 1136231:CORT_0B06540
uniprot id: H8X018
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0F00600
gene id: 1136231:CORT_0F00600
uniprot id: H8X8Z1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

1136231:CORT 0A01380
gene id: 1136231:CORT_0A01380
uniprot id: H8WVQ7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E00700
gene id: 1136231:CORT_0E00700
uniprot id: H8X6P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1136231:CORT 0H02510
gene id: 1136231:CORT_0H02510
uniprot id: H8XBB2
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1136231:CORT 0C02950
gene id: 1136231:CORT_0C02950
uniprot id: H8X3N3
names: Similarity
messages: Belongs to the TOP6A family.

1136231:CORT 0C05320
gene id: 1136231:CORT_0C05320
uniprot id: H8X346
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

1136231:CORT 0F02370
gene id: 1136231:CORT_0F02370
uniprot id: H8X8I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

1136231:CORT 0B05320
gene id: 1136231:CORT_0B05320
uniprot id: H8WZP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

1136231:CORT 0A08040
gene id: 1136231:CORT_0A08040
uniprot id: H8WX49
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A06900
gene id: 1136231:CORT_0A06900
uniprot id: H8WWT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA.
messages: Belongs to the CAF20 family.
messages: Cytoplasm

1136231:CORT 0A00800
gene id: 1136231:CORT_0A00800
uniprot id: H8WVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1136231:CORT 0A10560
gene id: 1136231:CORT_0A10560
uniprot id: H8WXD6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1136231:CORT 0C04440
gene id: 1136231:CORT_0C04440
uniprot id: H8X2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

1136231:CORT 0B00730
gene id: 1136231:CORT_0B00730
uniprot id: H8WZC6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D01680
gene id: 1136231:CORT_0D01680
uniprot id: H8X4S4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

1136231:CORT 0B07860
gene id: 1136231:CORT_0B07860
uniprot id: H8X1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

1136231:CORT 0B11250
gene id: 1136231:CORT_0B11250
uniprot id: H8X2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

1136231:CORT 0H01070
gene id: 1136231:CORT_0H01070
uniprot id: H8XAX5
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

1136231:CORT 0A04820
gene id: 1136231:CORT_0A04820
uniprot id: H8WXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP18 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

1136231:CORT 0E02280
gene id: 1136231:CORT_0E02280
uniprot id: H8X7N0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

1136231:CORT 0B02890
gene id: 1136231:CORT_0B02890
uniprot id: H8X0W4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A04340
gene id: 1136231:CORT_0A04340
uniprot id: H8WWJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

1136231:CORT 0B02180
gene id: 1136231:CORT_0B02180
uniprot id: H8X0P7
names: Similarity
messages: Belongs to the actin family.

1136231:CORT 0D06730
gene id: 1136231:CORT_0D06730
uniprot id: H8X5P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

1136231:CORT 0D07000
gene id: 1136231:CORT_0D07000
uniprot id: H8X5S5
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1136231:CORT 0A06560
gene id: 1136231:CORT_0A06560
uniprot id: H8WWQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

1136231:CORT 0G03560
gene id: 1136231:CORT_0G03560
uniprot id: H8XA55
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1136231:CORT 0G01410
gene id: 1136231:CORT_0G01410
uniprot id: H8XAH9
names: Similarity
messages: Belongs to the PhyH family.

1136231:CORT 0C06860
gene id: 1136231:CORT_0C06860
uniprot id: H8X4A6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A08290
gene id: 1136231:CORT_0A08290
uniprot id: H8WY99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

1136231:CORT 0H01700
gene id: 1136231:CORT_0H01700
uniprot id: H8XB34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

1136231:CORT 0G01920
gene id: 1136231:CORT_0G01920
uniprot id: H8XAM5
names: Similarity
messages: Belongs to the NOP10 family.

1136231:CORT 0C03290
gene id: 1136231:CORT_0C03290
uniprot id: H8X3R6
names: Similarity
messages: Belongs to the RMD1/sif2 family.

1136231:CORT 0C03280
gene id: 1136231:CORT_0C03280
uniprot id: H8X3R5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1136231:CORT 0B09970
gene id: 1136231:CORT_0B09970
uniprot id: H8X0I9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E03440
gene id: 1136231:CORT_0E03440
uniprot id: H8X704
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

1136231:CORT 0F04540
gene id: 1136231:CORT_0F04540
uniprot id: H8X9L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

1136231:CORT 0F01850
gene id: 1136231:CORT_0F01850
uniprot id: H8X8D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

1136231:CORT 0E03230
gene id: 1136231:CORT_0E03230
uniprot id: H8X6Y3
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0F01760
gene id: 1136231:CORT_0F01760
uniprot id: H8X8C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

1136231:CORT 0A11370
gene id: 1136231:CORT_0A11370
uniprot id: H8WYP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

1136231:CORT 0G00210
gene id: 1136231:CORT_0G00210
uniprot id: H8X9P6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1136231:CORT 0D06570
gene id: 1136231:CORT_0D06570
uniprot id: H8X5N3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B07420
gene id: 1136231:CORT_0B07420
uniprot id: H8X1P3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

1136231:CORT 0A10570
gene id: 1136231:CORT_0A10570
uniprot id: H8WXD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0A01950
gene id: 1136231:CORT_0A01950
uniprot id: H8WVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

1136231:CORT 0A10820
gene id: 1136231:CORT_0A10820
uniprot id: H8WXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

1136231:CORT 0B02700
gene id: 1136231:CORT_0B02700
uniprot id: H8X0U6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A02180
gene id: 1136231:CORT_0A02180
uniprot id: H8WVY5
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

1136231:CORT 0B11440
gene id: 1136231:CORT_0B11440
uniprot id: H8X2C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0D02910
gene id: 1136231:CORT_0D02910
uniprot id: H8X543
names: Similarity
messages: Belongs to the CWC26 family.

1136231:CORT 0C04570
gene id: 1136231:CORT_0C04570
uniprot id: H8X2X1
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

1136231:CORT 0B03180
gene id: 1136231:CORT_0B03180
uniprot id: H8X0Y9
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

1136231:CORT 0D01030
gene id: 1136231:CORT_0D01030
uniprot id: H8X4K9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1136231:CORT 0E00820
gene id: 1136231:CORT_0E00820
uniprot id: H8X6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0A04750
gene id: 1136231:CORT_0A04750
uniprot id: H8WXR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1136231:CORT 0A12040
gene id: 1136231:CORT_0A12040
uniprot id: H8WYV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0A10860
gene id: 1136231:CORT_0A10860
uniprot id: H8WXG5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

1136231:CORT 0D03390
gene id: 1136231:CORT_0D03390
uniprot id: H8X588
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1136231:CORT 0A01400
gene id: 1136231:CORT_0A01400
uniprot id: H8WVQ9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

1136231:CORT 0C02240
gene id: 1136231:CORT_0C02240
uniprot id: H8X2Q3
names: Similarity
messages: Belongs to the GST superfamily.

1136231:CORT 0D01490
gene id: 1136231:CORT_0D01490
uniprot id: H8X4Q5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F04220
gene id: 1136231:CORT_0F04220
uniprot id: H8X9I0
names: Similarity
messages: Belongs to the peptidase C19 family.

1136231:CORT 0B01870
gene id: 1136231:CORT_0B01870
uniprot id: H8X0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

1136231:CORT 0E02830
gene id: 1136231:CORT_0E02830
uniprot id: H8X7T4
names: Similarity
messages: Belongs to the PP2C family.

1136231:CORT 0C04620
gene id: 1136231:CORT_0C04620
uniprot id: H8X2X6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1136231:CORT 0C00660
gene id: 1136231:CORT_0C00660
uniprot id: H8X3H1
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

1136231:CORT 0C00370
gene id: 1136231:CORT_0C00370
uniprot id: H8X3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.
messages: P-body
messages: nucleoplasm

1136231:CORT 0E01320
gene id: 1136231:CORT_0E01320
uniprot id: H8X6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

1136231:CORT 0C01170
gene id: 1136231:CORT_0C01170
uniprot id: H8X2E7
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

1136231:CORT 0E03100
gene id: 1136231:CORT_0E03100
uniprot id: H8X6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

1136231:CORT 0F00170
gene id: 1136231:CORT_0F00170
uniprot id: H8X8U9
names: Similarity
messages: Belongs to the DeSI family.

1136231:CORT 0A01600
gene id: 1136231:CORT_0A01600
uniprot id: H8WVS8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: srp72, srp68, srp54, sec65, srp21 and srp14.
messages: Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes. SRP54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101. Both, SRP54 and SRP101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon). After signal sequence transfer, SRP54 and SRP101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association.
messages: The M domain binds the 7SL RNA and the signal sequence of presecretory proteins.
messages: The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit srp101. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

1136231:CORT 0D00960
gene id: 1136231:CORT_0D00960
uniprot id: H8X4K2
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

1136231:CORT 0F02210
gene id: 1136231:CORT_0F02210
uniprot id: H8X8H1
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

1136231:CORT 0B03920
gene id: 1136231:CORT_0B03920
uniprot id: H8X160
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

1136231:CORT 0B01970
gene id: 1136231:CORT_0B01970
uniprot id: H8X0M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0E04530
gene id: 1136231:CORT_0E04530
uniprot id: H8X7B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0E02190
gene id: 1136231:CORT_0E02190
uniprot id: H8X7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1136231:CORT 0A10250
gene id: 1136231:CORT_0A10250
uniprot id: H8WXA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

1136231:CORT 0G03330
gene id: 1136231:CORT_0G03330
uniprot id: H8XA33
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

1136231:CORT 0F02520
gene id: 1136231:CORT_0F02520
uniprot id: H8X8K2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1136231:CORT 0D00920
gene id: 1136231:CORT_0D00920
uniprot id: H8X4J8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A05240
gene id: 1136231:CORT_0A05240
uniprot id: H8WXW5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

1136231:CORT 0E02490
gene id: 1136231:CORT_0E02490
uniprot id: H8X7Q1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0F02280
gene id: 1136231:CORT_0F02280
uniprot id: H8X8H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

1136231:CORT 0B05840
gene id: 1136231:CORT_0B05840
uniprot id: H8WZU8
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1136231:CORT 0B11000
gene id: 1136231:CORT_0B11000
uniprot id: H8X277
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

1136231:CORT 0H01500
gene id: 1136231:CORT_0H01500
uniprot id: H8XB15
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A07950
gene id: 1136231:CORT_0A07950
uniprot id: H8WX41
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D07200
gene id: 1136231:CORT_0D07200
uniprot id: H8X6E2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

1136231:CORT 0A02060
gene id: 1136231:CORT_0A02060
uniprot id: H8WVX3
names: Similarity
messages: Belongs to the citrate synthase family.

1136231:CORT 0A07070
gene id: 1136231:CORT_0A07070
uniprot id: H8WWV2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

1136231:CORT 0B00540
gene id: 1136231:CORT_0B00540
uniprot id: H8WZA7
names: Similarity
messages: Belongs to the AAA ATPase family.

1136231:CORT 0A03320
gene id: 1136231:CORT_0A03320
uniprot id: H8WW96
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1136231:CORT 0C04760
gene id: 1136231:CORT_0C04760
uniprot id: H8X2Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

1136231:CORT 0D07655
gene id: 1136231:CORT_0D07655
uniprot id: H8X6I8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B02200
gene id: 1136231:CORT_0B02200
uniprot id: H8X0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

1136231:CORT 0D07330
gene id: 1136231:CORT_0D07330
uniprot id: H8X6F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136231:CORT 0G03520
gene id: 1136231:CORT_0G03520
uniprot id: H8XA51
names: Similarity
messages: Belongs to the bystin family.

1136231:CORT 0F01220
gene id: 1136231:CORT_0F01220
uniprot id: H8X951
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

1136231:CORT 0D01720
gene id: 1136231:CORT_0D01720
uniprot id: H8X4S8
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0H00250
gene id: 1136231:CORT_0H00250
uniprot id: H8XBF5
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

1136231:CORT 0D03750
gene id: 1136231:CORT_0D03750
uniprot id: H8X5C2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

1136231:CORT 0B10320
gene id: 1136231:CORT_0B10320
uniprot id: H8X215
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

1136231:CORT 0B04500
gene id: 1136231:CORT_0B04500
uniprot id: H8X1B8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1136231:CORT 0A08590
gene id: 1136231:CORT_0A08590
uniprot id: H8WYC8
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

1136231:CORT 0F01510
gene id: 1136231:CORT_0F01510
uniprot id: H8X979
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

1136231:CORT 0C03580
gene id: 1136231:CORT_0C03580
uniprot id: H8X3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

1136231:CORT 0B04230
gene id: 1136231:CORT_0B04230
uniprot id: H8X190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

1136231:CORT 0F02350
gene id: 1136231:CORT_0F02350
uniprot id: H8X8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

1136231:CORT 0A10350
gene id: 1136231:CORT_0A10350
uniprot id: H8WXB5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: Vacuole membrane

1136231:CORT 0B11530
gene id: 1136231:CORT_0B11530
uniprot id: H8X2D0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A07780
gene id: 1136231:CORT_0A07780
uniprot id: H8WX24
names: Similarity
messages: Belongs to the SWI5/SAE3 family.

1136231:CORT 0G02700
gene id: 1136231:CORT_0G02700
uniprot id: H8XAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

1136231:CORT 0C04230
gene id: 1136231:CORT_0C04230
uniprot id: H8X408
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0C03950
gene id: 1136231:CORT_0C03950
uniprot id: H8X3Y1
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1136231:CORT 0B10860
gene id: 1136231:CORT_0B10860
uniprot id: H8X266
names: Similarity
messages: Belongs to the FMO family.

1136231:CORT 0E03360
gene id: 1136231:CORT_0E03360
uniprot id: H8X6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

1136231:CORT 0D06280
gene id: 1136231:CORT_0D06280
uniprot id: H8X5K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0F01780
gene id: 1136231:CORT_0F01780
uniprot id: H8X8D0
names: Similarity
messages: Belongs to the peptidase M18 family.

1136231:CORT 0G01030
gene id: 1136231:CORT_0G01030
uniprot id: H8X9X4
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0E05180
gene id: 1136231:CORT_0E05180
uniprot id: H8X804
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

1136231:CORT 0B07900
gene id: 1136231:CORT_0B07900
uniprot id: H8X1U0
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

1136231:CORT 0G00480
gene id: 1136231:CORT_0G00480
uniprot id: H8X9S2
names: Similarity
messages: Belongs to the GroES chaperonin family.

1136231:CORT 0A09370
gene id: 1136231:CORT_0A09370
uniprot id: H8WYK6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C06450
gene id: 1136231:CORT_0C06450
uniprot id: H8X467
names: Similarity
messages: Belongs to the SGT1 family.

1136231:CORT 0A04780
gene id: 1136231:CORT_0A04780
uniprot id: H8WXR9
names: Similarity
messages: Belongs to the OSBP family.

1136231:CORT 0B02870
gene id: 1136231:CORT_0B02870
uniprot id: H8X0W2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0B11030
gene id: 1136231:CORT_0B11030
uniprot id: H8X280
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0F01660
gene id: 1136231:CORT_0F01660
uniprot id: H8X994
names: Similarity
messages: Belongs to the ATG16 family.

1136231:CORT 0C06720
gene id: 1136231:CORT_0C06720
uniprot id: H8X492
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1136231:CORT 0E05400
gene id: 1136231:CORT_0E05400
uniprot id: H8X826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B10010
gene id: 1136231:CORT_0B10010
uniprot id: H8X1Y4
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1136231:CORT 0B09730
gene id: 1136231:CORT_0B09730
uniprot id: H8X0G5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1136231:CORT 0B06230
gene id: 1136231:CORT_0B06230
uniprot id: H8WZY7
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

1136231:CORT 0F03330
gene id: 1136231:CORT_0F03330
uniprot id: H8X8T2
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

1136231:CORT 0D03510
gene id: 1136231:CORT_0D03510
uniprot id: H8X5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

1136231:CORT 0A06880
gene id: 1136231:CORT_0A06880
uniprot id: H8WWT3
names: Similarity
messages: Belongs to the TMA16 family.

1136231:CORT 0E00150
gene id: 1136231:CORT_0E00150
uniprot id: H8X6J5
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

1136231:CORT 0B07480
gene id: 1136231:CORT_0B07480
uniprot id: H8X1P9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A12710
gene id: 1136231:CORT_0A12710
uniprot id: H8WZ23
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1136231:CORT 0G04290
gene id: 1136231:CORT_0G04290
uniprot id: H8XAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

1136231:CORT 0C03800
gene id: 1136231:CORT_0C03800
uniprot id: H8X3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

1136231:CORT 0E02440
gene id: 1136231:CORT_0E02440
uniprot id: H8X7P6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

1136231:CORT 0D05530
gene id: 1136231:CORT_0D05530
uniprot id: H8X5D6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D03620
gene id: 1136231:CORT_0D03620
uniprot id: H8X5B0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D07580
gene id: 1136231:CORT_0D07580
uniprot id: H8X6I0
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1136231:CORT 0D04600
gene id: 1136231:CORT_0D04600
uniprot id: H8X652
names: Similarity
messages: Belongs to the peptidase S9B family.

1136231:CORT 0B07390
gene id: 1136231:CORT_0B07390
uniprot id: H8X1P0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

1136231:CORT 0C05550
gene id: 1136231:CORT_0C05550
uniprot id: H8X369
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1136231:CORT 0E03170
gene id: 1136231:CORT_0E03170
uniprot id: H8X6X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0D00240
gene id: 1136231:CORT_0D00240
uniprot id: H8X5V9
names: Similarity
messages: Belongs to the PIH1 family.

1136231:CORT 0E01130
gene id: 1136231:CORT_0E01130
uniprot id: H8X6U1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136231:CORT 0A10300
gene id: 1136231:CORT_0A10300
uniprot id: H8WXB0
names: Similarity
messages: Belongs to the COG4 family.

1136231:CORT 0B04610
gene id: 1136231:CORT_0B04610
uniprot id: H8X1C9
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1136231:CORT 0G00320
gene id: 1136231:CORT_0G00320
uniprot id: H8X9Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DDI1 family.
messages: Binds ubiquitin and polyubiquitinated proteins.
messages: Probable aspartic protease. May be involved in the regulation of exocytosis. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control.

1136231:CORT 0B01290
gene id: 1136231:CORT_0B01290
uniprot id: H8WZI0
names: Similarity
messages: Belongs to the AFG1 ATPase family.

1136231:CORT 0A07690
gene id: 1136231:CORT_0A07690
uniprot id: H8WX15
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

1136231:CORT 0A10070
gene id: 1136231:CORT_0A10070
uniprot id: H8WX87
names: Similarity
messages: Belongs to the SDHAF4 family.

1136231:CORT 0D00320
gene id: 1136231:CORT_0D00320
uniprot id: H8X5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1136231:CORT 0E00170
gene id: 1136231:CORT_0E00170
uniprot id: H8X6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

1136231:CORT 0A11140
gene id: 1136231:CORT_0A11140
uniprot id: H8WXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin NSP1/NUP62 family.
messages: Nucleus membrane

1136231:CORT 0A02820
gene id: 1136231:CORT_0A02820
uniprot id: H8WW48
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0G01780
gene id: 1136231:CORT_0G01780
uniprot id: H8XAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

1136231:CORT 0A00360
gene id: 1136231:CORT_0A00360
uniprot id: H8WVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1136231:CORT 0A06620
gene id: 1136231:CORT_0A06620
uniprot id: H8WWQ9
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0B09000
gene id: 1136231:CORT_0B09000
uniprot id: H8X092
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1136231:CORT 0A05290
gene id: 1136231:CORT_0A05290
uniprot id: H8WXX0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A08870
gene id: 1136231:CORT_0A08870
uniprot id: H8WYF6
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1136231:CORT 0B09820
gene id: 1136231:CORT_0B09820
uniprot id: H8X0H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

1136231:CORT 0B02380
gene id: 1136231:CORT_0B02380
uniprot id: H8X0R4
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

1136231:CORT 0A04060
gene id: 1136231:CORT_0A04060
uniprot id: H8WWH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

1136231:CORT 0B04380
gene id: 1136231:CORT_0B04380
uniprot id: H8X1A5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C03520
gene id: 1136231:CORT_0C03520
uniprot id: H8X3T8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136231:CORT 0A06330
gene id: 1136231:CORT_0A06330
uniprot id: H8WY72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

1136231:CORT 0A09870
gene id: 1136231:CORT_0A09870
uniprot id: H8WX67
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1136231:CORT 0C07180
gene id: 1136231:CORT_0C07180
uniprot id: H8X4D7
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A03520
gene id: 1136231:CORT_0A03520
uniprot id: H8WWB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1136231:CORT 0G02430
gene id: 1136231:CORT_0G02430
uniprot id: H8XAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

1136231:CORT 0B10440
gene id: 1136231:CORT_0B10440
uniprot id: H8X225
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1136231:CORT 0A12140
gene id: 1136231:CORT_0A12140
uniprot id: H8WYW7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1136231:CORT 0E06550
gene id: 1136231:CORT_0E06550
uniprot id: H8X7E2
names: Similarity
messages: Belongs to the threonine synthase family.

1136231:CORT 0D05510
gene id: 1136231:CORT_0D05510
uniprot id: H8X5D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

1136231:CORT 0A07090
gene id: 1136231:CORT_0A07090
uniprot id: H8WWV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0A10950
gene id: 1136231:CORT_0A10950
uniprot id: H8WXH4
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

1136231:CORT 0C07040
gene id: 1136231:CORT_0C07040
uniprot id: H8X4C3
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A05780
gene id: 1136231:CORT_0A05780
uniprot id: H8WY18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1136231:CORT 0D07550
gene id: 1136231:CORT_0D07550
uniprot id: H8X6H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1136231:CORT 0D05300
gene id: 1136231:CORT_0D05300
uniprot id: H8X6C1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1136231:CORT 0B06100
gene id: 1136231:CORT_0B06100
uniprot id: H8WZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1136231:CORT 0E03320
gene id: 1136231:CORT_0E03320
uniprot id: H8X6Z2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

1136231:CORT 0A00450
gene id: 1136231:CORT_0A00450
uniprot id: H8WVG6
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

1136231:CORT 0B03880
gene id: 1136231:CORT_0B03880
uniprot id: H8X156
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1136231:CORT 0D01170
gene id: 1136231:CORT_0D01170
uniprot id: H8X4M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1136231:CORT 0C00640
gene id: 1136231:CORT_0C00640
uniprot id: H8X3G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AEP2 family.
messages: Binds to the 5'UTR of the OLI1 mRNA.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.

1136231:CORT 0B10540
gene id: 1136231:CORT_0B10540
uniprot id: H8X236
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

1136231:CORT 0A12600
gene id: 1136231:CORT_0A12600
uniprot id: H8WZ13
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1136231:CORT 0D06910
gene id: 1136231:CORT_0D06910
uniprot id: H8X5R6
names: Similarity
messages: Belongs to the ATPase delta chain family.

1136231:CORT 0E04310
gene id: 1136231:CORT_0E04310
uniprot id: H8X789
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

1136231:CORT 0D01940
gene id: 1136231:CORT_0D01940
uniprot id: H8X4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1136231:CORT 0A04640
gene id: 1136231:CORT_0A04640
uniprot id: H8WWM8
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0E03780
gene id: 1136231:CORT_0E03780
uniprot id: H8X738
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUR1 family.
messages: Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability. Required for rDNA repeat stability.
messages: Membrane
messages: Nucleus membrane

1136231:CORT 0A13390
gene id: 1136231:CORT_0A13390
uniprot id: H8WXP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
messages: cytoskeleton
messages: nuclear pore complex

1136231:CORT 0C05560
gene id: 1136231:CORT_0C05560
uniprot id: H8X370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1136231:CORT 0E02000
gene id: 1136231:CORT_0E02000
uniprot id: H8X7K4
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

1136231:CORT 0A12440
gene id: 1136231:CORT_0A12440
uniprot id: H8WYZ7
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1136231:CORT 0E00810
gene id: 1136231:CORT_0E00810
uniprot id: H8X6Q9
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1136231:CORT 0A04070
gene id: 1136231:CORT_0A04070
uniprot id: H8WWH1
names: Similarity
messages: Belongs to the peptidase S8 family.

1136231:CORT 0A09540
gene id: 1136231:CORT_0A09540
uniprot id: H8WYM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

1136231:CORT 0F02580
gene id: 1136231:CORT_0F02580
uniprot id: H8X8K7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0F01460
gene id: 1136231:CORT_0F01460
uniprot id: H8X974
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0C06990
gene id: 1136231:CORT_0C06990
uniprot id: H8X4B8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1136231:CORT 0F03460
gene id: 1136231:CORT_0F03460
uniprot id: H8X9A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-A family.
messages: Mitochondrion

1136231:CORT 0E01310
gene id: 1136231:CORT_0E01310
uniprot id: H8X6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEF1 family.
messages: Cytoplasm
messages: Nucleus
messages: telomere

1136231:CORT 0A05400
gene id: 1136231:CORT_0A05400
uniprot id: H8WXY1
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H00230
gene id: 1136231:CORT_0H00230
uniprot id: H8XBF3
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

1136231:CORT 0A02020
gene id: 1136231:CORT_0A02020
uniprot id: H8WVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

1136231:CORT 0A11170
gene id: 1136231:CORT_0A11170
uniprot id: H8WXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0C00210
gene id: 1136231:CORT_0C00210
uniprot id: H8X3C7
names: Function
names: Similarity
messages: Belongs to the Rab GDI family.
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

1136231:CORT 0D04620
gene id: 1136231:CORT_0D04620
uniprot id: H8X654
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1136231:CORT 0D00330
gene id: 1136231:CORT_0D00330
uniprot id: H8X5W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

1136231:CORT 0D03640
gene id: 1136231:CORT_0D03640
uniprot id: H8X5B2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfate adenylyltransferase family.
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The oligomerization domain is distantly related to APS kinases, but it is not functional and does not bind APS. It is required for oligomerization of the enzyme, although the oligomerization state has no effect on the catalytic activity of the enzyme.

1136231:CORT 0B10110
gene id: 1136231:CORT_0B10110
uniprot id: H8X1Z4
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

1136231:CORT 0A09940
gene id: 1136231:CORT_0A09940
uniprot id: H8WX74
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H02360
gene id: 1136231:CORT_0H02360
uniprot id: H8XB97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0C04040
gene id: 1136231:CORT_0C04040
uniprot id: H8X3Z0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D00450
gene id: 1136231:CORT_0D00450
uniprot id: H8X5X9
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

1136231:CORT 0H01300
gene id: 1136231:CORT_0H01300
uniprot id: H8XAZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO70 family.
messages: Bud

1136231:CORT 0A12330
gene id: 1136231:CORT_0A12330
uniprot id: H8WYY6
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A04490
gene id: 1136231:CORT_0A04490
uniprot id: H8WWL3
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

1136231:CORT 0B07770
gene id: 1136231:CORT_0B07770
uniprot id: H8X1S7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-67 and Arg-70) that bind to malonylated and succinylated substrates and define the specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.

1136231:CORT 0B08270
gene id: 1136231:CORT_0B08270
uniprot id: H8X1X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

1136231:CORT 0H02520
gene id: 1136231:CORT_0H02520
uniprot id: H8XBB3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0E02760
gene id: 1136231:CORT_0E02760
uniprot id: H8X7S7
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

1136231:CORT 0B01900
gene id: 1136231:CORT_0B01900
uniprot id: H8X0L9
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1136231:CORT 0A09400
gene id: 1136231:CORT_0A09400
uniprot id: H8WYK9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B06880
gene id: 1136231:CORT_0B06880
uniprot id: H8X1J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

1136231:CORT 0C02745
gene id: 1136231:CORT_0C02745
uniprot id: H8X3L2
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0C01350
gene id: 1136231:CORT_0C01350
uniprot id: H8X2G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

1136231:CORT 0A09320
gene id: 1136231:CORT_0A09320
uniprot id: H8WYK1
names: Similarity
messages: Belongs to the UPF0538 family.

1136231:CORT 0D06870
gene id: 1136231:CORT_0D06870
uniprot id: H8X5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

1136231:CORT 0F04450
gene id: 1136231:CORT_0F04450
uniprot id: H8X9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

1136231:CORT 0D00890
gene id: 1136231:CORT_0D00890
uniprot id: H8X4J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

1136231:CORT 0A08150
gene id: 1136231:CORT_0A08150
uniprot id: H8WY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

1136231:CORT 0B09860
gene id: 1136231:CORT_0B09860
uniprot id: H8X0H8
names: Similarity
messages: Belongs to the TFIIB family.

1136231:CORT 0F01720
gene id: 1136231:CORT_0F01720
uniprot id: H8X9A0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

1136231:CORT 0E02880
gene id: 1136231:CORT_0E02880
uniprot id: H8X7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1136231:CORT 0F02470
gene id: 1136231:CORT_0F02470
uniprot id: H8X8J7
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

1136231:CORT 0A13420
gene id: 1136231:CORT_0A13420
uniprot id: H8WXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

1136231:CORT 0E04470
gene id: 1136231:CORT_0E04470
uniprot id: H8X7A4
names: Similarity
messages: Belongs to the frataxin family.

1136231:CORT 0B03200
gene id: 1136231:CORT_0B03200
uniprot id: H8X0Z1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1136231:CORT 0B08170
gene id: 1136231:CORT_0B08170
uniprot id: H8X1W6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1136231:CORT 0A09720
gene id: 1136231:CORT_0A09720
uniprot id: H8WX52
names: Similarity
messages: Belongs to the MT-A70-like family.

1136231:CORT 0C02490
gene id: 1136231:CORT_0C02490
uniprot id: H8X2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

1136231:CORT 0H01420
gene id: 1136231:CORT_0H01420
uniprot id: H8XB07
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0E04880
gene id: 1136231:CORT_0E04880
uniprot id: H8X7X3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D00580
gene id: 1136231:CORT_0D00580
uniprot id: H8X4G4
names: Similarity
messages: Belongs to the thioredoxin family.

1136231:CORT 0B11360
gene id: 1136231:CORT_0B11360
uniprot id: H8X2B3
names: Similarity
messages: Belongs to the TSR2 family.

1136231:CORT 0B09425
gene id: 1136231:CORT_0B09425
uniprot id: H8X0D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

1136231:CORT 0C01290
gene id: 1136231:CORT_0C01290
uniprot id: H8X2F9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

1136231:CORT 0D02750
gene id: 1136231:CORT_0D02750
uniprot id: H8X527
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

1136231:CORT 0E04260
gene id: 1136231:CORT_0E04260
uniprot id: H8X784
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1136231:CORT 0F04120
gene id: 1136231:CORT_0F04120
uniprot id: H8X9H0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1136231:CORT 0D05870
gene id: 1136231:CORT_0D05870
uniprot id: H8X5G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. SKI2 subfamily.
messages: Cytoplasm

1136231:CORT 0A02730
gene id: 1136231:CORT_0A02730
uniprot id: H8WW39
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136231:CORT 0C04840
gene id: 1136231:CORT_0C04840
uniprot id: H8X2Z8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1136231:CORT 0C02570
gene id: 1136231:CORT_0C02570
uniprot id: H8X2T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1136231:CORT 0A05180
gene id: 1136231:CORT_0A05180
uniprot id: H8WXV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0G00190
gene id: 1136231:CORT_0G00190
uniprot id: H8X9P4
names: Similarity
messages: Belongs to the hexokinase family.

1136231:CORT 0A03250
gene id: 1136231:CORT_0A03250
uniprot id: H8WW89
names: Similarity
messages: Belongs to the nudE family.

1136231:CORT 0H01290
gene id: 1136231:CORT_0H01290
uniprot id: H8XAZ7
names: Similarity
messages: Belongs to the TRL1 family.

1136231:CORT 0A13300
gene id: 1136231:CORT_0A13300
uniprot id: H8WXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

1136231:CORT 0F01160
gene id: 1136231:CORT_0F01160
uniprot id: H8X945
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.

1136231:CORT 0A10880
gene id: 1136231:CORT_0A10880
uniprot id: H8WXG7
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0B09870
gene id: 1136231:CORT_0B09870
uniprot id: H8X0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

1136231:CORT 0F00260
gene id: 1136231:CORT_0F00260
uniprot id: H8X8V7
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A05870
gene id: 1136231:CORT_0A05870
uniprot id: H8WY27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

1136231:CORT 0C04190
gene id: 1136231:CORT_0C04190
uniprot id: H8X404
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

1136231:CORT 0A02230
gene id: 1136231:CORT_0A02230
uniprot id: H8WVZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
messages: Nucleus

1136231:CORT 0B00290
gene id: 1136231:CORT_0B00290
uniprot id: H8WZ84
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1136231:CORT 0E04980
gene id: 1136231:CORT_0E04980
uniprot id: H8X7Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

1136231:CORT 0B07450
gene id: 1136231:CORT_0B07450
uniprot id: H8X1P6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

1136231:CORT 0A04290
gene id: 1136231:CORT_0A04290
uniprot id: H8WWJ3
names: Similarity
messages: Belongs to the threonine aldolase family.

1136231:CORT 0A00330
gene id: 1136231:CORT_0A00330
uniprot id: H8WVF5
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0F00640
gene id: 1136231:CORT_0F00640
uniprot id: H8X8Z5
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0E05710
gene id: 1136231:CORT_0E05710
uniprot id: H8X856
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

1136231:CORT 0D04890
gene id: 1136231:CORT_0D04890
uniprot id: H8X681
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0A09740
gene id: 1136231:CORT_0A09740
uniprot id: H8WX54
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136231:CORT 0A03750
gene id: 1136231:CORT_0A03750
uniprot id: H8WWD9
names: Similarity
messages: Belongs to the exportin family.

1136231:CORT 0A13130
gene id: 1136231:CORT_0A13130
uniprot id: H8WXM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

1136231:CORT 0A01130
gene id: 1136231:CORT_0A01130
uniprot id: H8WVN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

1136231:CORT 0A12900
gene id: 1136231:CORT_0A12900
uniprot id: H8WZ41
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

1136231:CORT 0D03740
gene id: 1136231:CORT_0D03740
uniprot id: H8X5C1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B08900
gene id: 1136231:CORT_0B08900
uniprot id: H8X082
names: Similarity
messages: Belongs to the DCP1 family.

1136231:CORT 0A12560
gene id: 1136231:CORT_0A12560
uniprot id: H8WZ09
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

1136231:CORT 0B05450
gene id: 1136231:CORT_0B05450
uniprot id: H8WZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0B01560
gene id: 1136231:CORT_0B01560
uniprot id: H8WZK7
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the microtubule organizing center (MTOC).

1136231:CORT 0B05470
gene id: 1136231:CORT_0B05470
uniprot id: H8WZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSA1 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1136231:CORT 0E05860
gene id: 1136231:CORT_0E05860
uniprot id: H8X870
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.

1136231:CORT 0A11920
gene id: 1136231:CORT_0A11920
uniprot id: H8WYU5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

1136231:CORT 0A10310
gene id: 1136231:CORT_0A10310
uniprot id: H8WXB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm
messages: Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.
messages: Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.
messages: Mitochondrion
messages: The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.

1136231:CORT 0F03980
gene id: 1136231:CORT_0F03980
uniprot id: H8X9F6
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A05110
gene id: 1136231:CORT_0A05110
uniprot id: H8WXV2
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

1136231:CORT 0D04870
gene id: 1136231:CORT_0D04870
uniprot id: H8X679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

1136231:CORT 0A11855
gene id: 1136231:CORT_0A11855
uniprot id: H8WYT9
names: Function
names: Similarity
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.

1136231:CORT 0G04440
gene id: 1136231:CORT_0G04440
uniprot id: H8XAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

1136231:CORT 0F03840
gene id: 1136231:CORT_0F03840
uniprot id: H8X9E2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

1136231:CORT 0E01250
gene id: 1136231:CORT_0E01250
uniprot id: H8X6V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

1136231:CORT 0E00470
gene id: 1136231:CORT_0E00470
uniprot id: H8X6M6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1136231:CORT 0B01010
gene id: 1136231:CORT_0B01010
uniprot id: H8WZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0G02300
gene id: 1136231:CORT_0G02300
uniprot id: H8XAR0
names: Similarity
names: Subunit
messages: Belongs to the SIL1 family.
messages: Interacts with KAR2.

1136231:CORT 0D06660
gene id: 1136231:CORT_0D06660
uniprot id: H8X5P2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

1136231:CORT 0A03430
gene id: 1136231:CORT_0A03430
uniprot id: H8WWA7
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

1136231:CORT 0A13480
gene id: 1136231:CORT_0A13480
uniprot id: H8WXQ8
names: Similarity
messages: Belongs to the lipin family.

1136231:CORT 0B05870
gene id: 1136231:CORT_0B05870
uniprot id: H8WZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0A05830
gene id: 1136231:CORT_0A05830
uniprot id: H8WY23
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

1136231:CORT 0E03970
gene id: 1136231:CORT_0E03970
uniprot id: H8X756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1136231:CORT 0C02530
gene id: 1136231:CORT_0C02530
uniprot id: H8X2T1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

1136231:CORT 0A00270
gene id: 1136231:CORT_0A00270
uniprot id: H8WVE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0G01530
gene id: 1136231:CORT_0G01530
uniprot id: H8XAJ1
names: Subcellular Location Annotation
messages: nucleolus

1136231:CORT 0H01890
gene id: 1136231:CORT_0H01890
uniprot id: H8XB53
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1136231:CORT 0D00860
gene id: 1136231:CORT_0D00860
uniprot id: H8X4J2
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0C05140
gene id: 1136231:CORT_0C05140
uniprot id: H8X328
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A11850
gene id: 1136231:CORT_0A11850
uniprot id: H8WYT8
names: Subcellular Location Annotation
messages: Peroxisome membrane

1136231:CORT 0A09880
gene id: 1136231:CORT_0A09880
uniprot id: H8WX68
names: Function
names: Subcellular Location Annotation
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
messages: Nucleus

1136231:CORT 0E05540
gene id: 1136231:CORT_0E05540
uniprot id: H8X840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

1136231:CORT 0F03890
gene id: 1136231:CORT_0F03890
uniprot id: H8X9E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

1136231:CORT 0C06200
gene id: 1136231:CORT_0C06200
uniprot id: H8X441
names: Similarity
messages: Belongs to the WrbA family.

1136231:CORT 0B01110
gene id: 1136231:CORT_0B01110
uniprot id: H8WZG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

1136231:CORT 0B01000
gene id: 1136231:CORT_0B01000
uniprot id: H8WZF2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1136231:CORT 0B11100
gene id: 1136231:CORT_0B11100
uniprot id: H8X287
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

1136231:CORT 0A00970
gene id: 1136231:CORT_0A00970
uniprot id: H8WVL5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1136231:CORT 0E02270
gene id: 1136231:CORT_0E02270
uniprot id: H8X7M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1136231:CORT 0E02750
gene id: 1136231:CORT_0E02750
uniprot id: H8X7S6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1136231:CORT 0H01490
gene id: 1136231:CORT_0H01490
uniprot id: H8XB14
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

1136231:CORT 0A01590
gene id: 1136231:CORT_0A01590
uniprot id: H8WVS7
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

1136231:CORT 0A10720
gene id: 1136231:CORT_0A10720
uniprot id: H8WXF2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

1136231:CORT 0E04110
gene id: 1136231:CORT_0E04110
uniprot id: H8X769
names: Subcellular Location Annotation
messages: Membrane
messages: Preautophagosomal structure membrane

1136231:CORT 0G01370
gene id: 1136231:CORT_0G01370
uniprot id: H8XAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0A08850
gene id: 1136231:CORT_0A08850
uniprot id: H8WYF4
names: Similarity
messages: Belongs to the SH3YL1 family.

1136231:CORT 0G02150
gene id: 1136231:CORT_0G02150
uniprot id: H8XAP6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

1136231:CORT 0B02690
gene id: 1136231:CORT_0B02690
uniprot id: H8X0U5
names: Function
messages: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.

1136231:CORT 0B09010
gene id: 1136231:CORT_0B09010
uniprot id: H8X093
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1136231:CORT 0F02030
gene id: 1136231:CORT_0F02030
uniprot id: H8X8F3
names: Similarity
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.

1136231:CORT 0E00660
gene id: 1136231:CORT_0E00660
uniprot id: H8X6P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0G00180
gene id: 1136231:CORT_0G00180
uniprot id: H8X9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Endoplasmic reticulum membrane

1136231:CORT 0A04380
gene id: 1136231:CORT_0A04380
uniprot id: H8WWK2
names: Subcellular Location Annotation
messages: Cytoplasm

1136231:CORT 0D07340
gene id: 1136231:CORT_0D07340
uniprot id: H8X6F6
names: Similarity
messages: Belongs to the group II decarboxylase family.

1136231:CORT 0B00550
gene id: 1136231:CORT_0B00550
uniprot id: H8WZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

1136231:CORT 0B09750
gene id: 1136231:CORT_0B09750
uniprot id: H8X0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

1136231:CORT 0B04150
gene id: 1136231:CORT_0B04150
uniprot id: H8X182
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

1136231:CORT 0A03130
gene id: 1136231:CORT_0A03130
uniprot id: H8WW78
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C04720
gene id: 1136231:CORT_0C04720
uniprot id: H8X2Y6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

1136231:CORT 0A07180
gene id: 1136231:CORT_0A07180
uniprot id: H8WWW3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136231:CORT 0A02840
gene id: 1136231:CORT_0A02840
uniprot id: H8WW50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1136231:CORT 0A08550
gene id: 1136231:CORT_0A08550
uniprot id: H8WYC4
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1136231:CORT 0A03490
gene id: 1136231:CORT_0A03490
uniprot id: H8WWB3
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A08680
gene id: 1136231:CORT_0A08680
uniprot id: H8WYD7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

1136231:CORT 0B03760
gene id: 1136231:CORT_0B03760
uniprot id: H8X144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1136231:CORT 0F03920
gene id: 1136231:CORT_0F03920
uniprot id: H8X9F0
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

1136231:CORT 0E06280
gene id: 1136231:CORT_0E06280
uniprot id: H8X8B1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

1136231:CORT 0D04000
gene id: 1136231:CORT_0D04000
uniprot id: H8X5Z2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H00140
gene id: 1136231:CORT_0H00140
uniprot id: H8XBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

1136231:CORT 0E02680
gene id: 1136231:CORT_0E02680
uniprot id: H8X7R9
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

1136231:CORT 0D06770
gene id: 1136231:CORT_0D06770
uniprot id: H8X5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0F03820
gene id: 1136231:CORT_0F03820
uniprot id: H8X9E0
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

1136231:CORT 0D02090
gene id: 1136231:CORT_0D02090
uniprot id: H8X4W5
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

1136231:CORT 0H00620
gene id: 1136231:CORT_0H00620
uniprot id: H8XBJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

1136231:CORT 0E04070
gene id: 1136231:CORT_0E04070
uniprot id: H8X766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0D00150
gene id: 1136231:CORT_0D00150
uniprot id: H8X5V0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1136231:CORT 0C02470
gene id: 1136231:CORT_0C02470
uniprot id: H8X2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

1136231:CORT 0B09920
gene id: 1136231:CORT_0B09920
uniprot id: H8X0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

1136231:CORT 0E02210
gene id: 1136231:CORT_0E02210
uniprot id: H8X7M3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1136231:CORT 0A08330
gene id: 1136231:CORT_0A08330
uniprot id: H8WYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1136231:CORT 0B04790
gene id: 1136231:CORT_0B04790
uniprot id: H8X1E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

1136231:CORT 0C02420
gene id: 1136231:CORT_0C02420
uniprot id: H8X2S0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

1136231:CORT 0C01660
gene id: 1136231:CORT_0C01660
uniprot id: H8X2J6
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

1136231:CORT 0F03670
gene id: 1136231:CORT_0F03670
uniprot id: H8X9C4
names: Similarity
messages: Belongs to the ZNF598/HEL2 family.

1136231:CORT 0E05110
gene id: 1136231:CORT_0E05110
uniprot id: H8X7Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

1136231:CORT 0A11440
gene id: 1136231:CORT_0A11440
uniprot id: H8WYP7
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G01540
gene id: 1136231:CORT_0G01540
uniprot id: H8XAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

1136231:CORT 0B04090
gene id: 1136231:CORT_0B04090
uniprot id: H8X176
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A11090
gene id: 1136231:CORT_0A11090
uniprot id: H8WXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1136231:CORT 0E00730
gene id: 1136231:CORT_0E00730
uniprot id: H8X6Q1
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

1136231:CORT 0E01330
gene id: 1136231:CORT_0E01330
uniprot id: H8X6W0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1136231:CORT 0C06050
gene id: 1136231:CORT_0C06050
uniprot id: H8X426
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

1136231:CORT 0A03510
gene id: 1136231:CORT_0A03510
uniprot id: H8WWB5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0F04110
gene id: 1136231:CORT_0F04110
uniprot id: H8X9G9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

1136231:CORT 0A02070
gene id: 1136231:CORT_0A02070
uniprot id: H8WVX4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0D04180
gene id: 1136231:CORT_0D04180
uniprot id: H8X610
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

1136231:CORT 0D06380
gene id: 1136231:CORT_0D06380
uniprot id: H8X5L6
names: Similarity
messages: Belongs to the OMP decarboxylase family.

1136231:CORT 0D03910
gene id: 1136231:CORT_0D03910
uniprot id: H8X5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

1136231:CORT 0F03100
gene id: 1136231:CORT_0F03100
uniprot id: H8X8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1136231:CORT 0C05500
gene id: 1136231:CORT_0C05500
uniprot id: H8X364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0H01960
gene id: 1136231:CORT_0H01960
uniprot id: H8XB60
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A01920
gene id: 1136231:CORT_0A01920
uniprot id: H8WVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

1136231:CORT 0F04740
gene id: 1136231:CORT_0F04740
uniprot id: H8X9N3
names: Similarity
messages: Belongs to the RCAN family.

1136231:CORT 0C06850
gene id: 1136231:CORT_0C06850
uniprot id: H8X4A5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

1136231:CORT 0C03410
gene id: 1136231:CORT_0C03410
uniprot id: H8X3S8
names: Similarity
messages: Belongs to the SURF6 family.

1136231:CORT 0C01640
gene id: 1136231:CORT_0C01640
uniprot id: H8X2J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

1136231:CORT 0H01900
gene id: 1136231:CORT_0H01900
uniprot id: H8XB54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1136231:CORT 0F04130
gene id: 1136231:CORT_0F04130
uniprot id: H8X9H1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0E00670
gene id: 1136231:CORT_0E00670
uniprot id: H8X6P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0C01020
gene id: 1136231:CORT_0C01020
uniprot id: H8X3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus
messages: Responsible for methylating the 5'-cap structure of mRNAs.

1136231:CORT 0A09090
gene id: 1136231:CORT_0A09090
uniprot id: H8WYH8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1136231:CORT 0E05830
gene id: 1136231:CORT_0E05830
uniprot id: H8X867
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1136231:CORT 0B09570
gene id: 1136231:CORT_0B09570
uniprot id: H8X0E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC19 family.
messages: Nucleus
messages: kinetochore

1136231:CORT 0F04430
gene id: 1136231:CORT_0F04430
uniprot id: H8X9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

1136231:CORT 0B11330
gene id: 1136231:CORT_0B11330
uniprot id: H8X2B0
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

1136231:CORT 0D05370
gene id: 1136231:CORT_0D05370
uniprot id: H8X6C8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1136231:CORT 0C01500
gene id: 1136231:CORT_0C01500
uniprot id: H8X2I0
names: Similarity
messages: Belongs to the LOC1 family.

1136231:CORT 0C02370
gene id: 1136231:CORT_0C02370
uniprot id: H8X2R6
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

1136231:CORT 0C01770
gene id: 1136231:CORT_0C01770
uniprot id: H8X2K7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0A02760
gene id: 1136231:CORT_0A02760
uniprot id: H8WW42
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0F01930
gene id: 1136231:CORT_0F01930
uniprot id: H8X8E5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136231:CORT 0D02860
gene id: 1136231:CORT_0D02860
uniprot id: H8X538
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

1136231:CORT 0E02770
gene id: 1136231:CORT_0E02770
uniprot id: H8X7S8
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

1136231:CORT 0E01210
gene id: 1136231:CORT_0E01210
uniprot id: H8X6U9
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

1136231:CORT 0B00110
gene id: 1136231:CORT_0B00110
uniprot id: H8WZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

1136231:CORT 0C01940
gene id: 1136231:CORT_0C01940
uniprot id: H8X2M3
names: Similarity
messages: Belongs to the SEN54 family.

1136231:CORT 0B09550
gene id: 1136231:CORT_0B09550
uniprot id: H8X0E7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0F04230
gene id: 1136231:CORT_0F04230
uniprot id: H8X9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTT106 family.
messages: Nucleus

1136231:CORT 0A10420
gene id: 1136231:CORT_0A10420
uniprot id: H8WXC2
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0H01740
gene id: 1136231:CORT_0H01740
uniprot id: H8XB38
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1136231:CORT 0D06670
gene id: 1136231:CORT_0D06670
uniprot id: H8X5P3
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1136231:CORT 0C05400
gene id: 1136231:CORT_0C05400
uniprot id: H8X354
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A03540
gene id: 1136231:CORT_0A03540
uniprot id: H8WWB8
names: Subcellular Location Annotation
messages: nuclear pore complex

1136231:CORT 0A04520
gene id: 1136231:CORT_0A04520
uniprot id: H8WWL6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1136231:CORT 0E05320
gene id: 1136231:CORT_0E05320
uniprot id: H8X818
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1136231:CORT 0E03680
gene id: 1136231:CORT_0E03680
uniprot id: H8X728
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A02380
gene id: 1136231:CORT_0A02380
uniprot id: H8WW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

1136231:CORT 0B06170
gene id: 1136231:CORT_0B06170
uniprot id: H8WZY1
names: Subcellular Location Annotation
messages: Mitochondrion

1136231:CORT 0B01840
gene id: 1136231:CORT_0B01840
uniprot id: H8X0L3
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

1136231:CORT 0A10140
gene id: 1136231:CORT_0A10140
uniprot id: H8WX94
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A01050
gene id: 1136231:CORT_0A01050
uniprot id: H8WVM4
names: Subcellular Location Annotation
messages: Nucleus membrane

1136231:CORT 0A11550
gene id: 1136231:CORT_0A11550
uniprot id: H8WYQ8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136231:CORT 0B00800
gene id: 1136231:CORT_0B00800
uniprot id: H8WZD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALS family.
messages: Cell membrane
messages: Membrane
messages: cell wall

1136231:CORT 0D02070
gene id: 1136231:CORT_0D02070
uniprot id: H8X4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHZ1 family.
messages: Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.
messages: Nucleus

1136231:CORT 0E01910
gene id: 1136231:CORT_0E01910
uniprot id: H8X7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMA20 family.
messages: Cytoplasm
messages: Involved in translation.

1136231:CORT 0B03800
gene id: 1136231:CORT_0B03800
uniprot id: H8X148
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.

1136231:CORT 0A03550
gene id: 1136231:CORT_0A03550
uniprot id: H8WWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

1136231:CORT 0B03820
gene id: 1136231:CORT_0B03820
uniprot id: H8X150
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0D00880
gene id: 1136231:CORT_0D00880
uniprot id: H8X4J4
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0G01110
gene id: 1136231:CORT_0G01110
uniprot id: H8X9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1136231:CORT 0B07680
gene id: 1136231:CORT_0B07680
uniprot id: H8X1R9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1136231:CORT 0D03520
gene id: 1136231:CORT_0D03520
uniprot id: H8X5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

1136231:CORT 0E03220
gene id: 1136231:CORT_0E03220
uniprot id: H8X6Y2
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0A13410
gene id: 1136231:CORT_0A13410
uniprot id: H8WXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
messages: Nucleus

1136231:CORT 0A08620
gene id: 1136231:CORT_0A08620
uniprot id: H8WYD1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

1136231:CORT 0A08940
gene id: 1136231:CORT_0A08940
uniprot id: H8WYG3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B11570
gene id: 1136231:CORT_0B11570
uniprot id: H8X2D4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1136231:CORT 0A10210
gene id: 1136231:CORT_0A10210
uniprot id: H8WXA1
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

1136231:CORT 0A09550
gene id: 1136231:CORT_0A09550
uniprot id: H8WYM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

1136231:CORT 0B00210
gene id: 1136231:CORT_0B00210
uniprot id: H8WZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

1136231:CORT 0E06010
gene id: 1136231:CORT_0E06010
uniprot id: H8X884
names: Similarity
messages: Belongs to the cyclin family.

1136231:CORT 0A07540
gene id: 1136231:CORT_0A07540
uniprot id: H8WX00
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136231:CORT 0C00730
gene id: 1136231:CORT_0C00730
uniprot id: H8X3H8
names: Function
names: Similarity
messages: Belongs to the misato family.
messages: Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.

1136231:CORT 0A04860
gene id: 1136231:CORT_0A04860
uniprot id: H8WXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

1136231:CORT 0C03300
gene id: 1136231:CORT_0C03300
uniprot id: H8X3R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

1136231:CORT 0G02370
gene id: 1136231:CORT_0G02370
uniprot id: H8XAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

1136231:CORT 0D01540
gene id: 1136231:CORT_0D01540
uniprot id: H8X4R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

1136231:CORT 0D06400
gene id: 1136231:CORT_0D06400
uniprot id: H8X5L8
names: Similarity
messages: Belongs to the RENT3 family.

1136231:CORT 0F01740
gene id: 1136231:CORT_0F01740
uniprot id: H8X8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

1136231:CORT 0D03610
gene id: 1136231:CORT_0D03610
uniprot id: H8X5A9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0G03700
gene id: 1136231:CORT_0G03700
uniprot id: H8XA69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

1136231:CORT 0C03690
gene id: 1136231:CORT_0C03690
uniprot id: H8X3V6
names: Similarity
messages: Belongs to the AAA ATPase family.

1136231:CORT 0E02180
gene id: 1136231:CORT_0E02180
uniprot id: H8X7M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.
messages: Endoplasmic reticulum membrane
messages: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.
messages: Membrane

1136231:CORT 0E03020
gene id: 1136231:CORT_0E03020
uniprot id: H8X7V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: actin patch

1136231:CORT 0A04320
gene id: 1136231:CORT_0A04320
uniprot id: H8WWJ6
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1136231:CORT 0A12340
gene id: 1136231:CORT_0A12340
uniprot id: H8WYY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.

1136231:CORT 0G01220
gene id: 1136231:CORT_0G01220
uniprot id: H8XAG0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1136231:CORT 0C06880
gene id: 1136231:CORT_0C06880
uniprot id: H8X4A8
names: Similarity
messages: Belongs to the BLM10 family.

1136231:CORT 0A07260
gene id: 1136231:CORT_0A07260
uniprot id: H8WWX1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

1136231:CORT 0G01070
gene id: 1136231:CORT_0G01070
uniprot id: H8X9X8
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

1136231:CORT 0D03040
gene id: 1136231:CORT_0D03040
uniprot id: H8X556
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.

1136231:CORT 0F02330
gene id: 1136231:CORT_0F02330
uniprot id: H8X8I3
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

1136231:CORT 0D03630
gene id: 1136231:CORT_0D03630
uniprot id: H8X5B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1136231:CORT 0G00860
gene id: 1136231:CORT_0G00860
uniprot id: H8X9V7
names: Similarity
messages: Belongs to the SIN1 family.

1136231:CORT 0A07200
gene id: 1136231:CORT_0A07200
uniprot id: H8WWW5
names: Function
names: Similarity
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the RRM CWC2 family.
messages: Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle.

1136231:CORT 0D04760
gene id: 1136231:CORT_0D04760
uniprot id: H8X668
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136231:CORT 0B08660
gene id: 1136231:CORT_0B08660
uniprot id: H8X058
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: Membrane
messages: autophagosome membrane

1136231:CORT 0D05940
gene id: 1136231:CORT_0D05940
uniprot id: H8X5H6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136231:CORT 0C06300
gene id: 1136231:CORT_0C06300
uniprot id: H8X452
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

1136231:CORT 0B08440
gene id: 1136231:CORT_0B08440
uniprot id: H8X037
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1136231:CORT 0B00770
gene id: 1136231:CORT_0B00770
uniprot id: H8WZD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0G01990
gene id: 1136231:CORT_0G01990
uniprot id: H8XAN0
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1136231:CORT 0D06810
gene id: 1136231:CORT_0D06810
uniprot id: H8X5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

1136231:CORT 0C05980
gene id: 1136231:CORT_0C05980
uniprot id: H8X3B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

1136231:CORT 0H02080
gene id: 1136231:CORT_0H02080
uniprot id: H8XB70
names: Similarity
messages: Belongs to the PPP phosphatase family.

1136231:CORT 0F02820
gene id: 1136231:CORT_0F02820
uniprot id: H8X8N1
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

1136231:CORT 0G01870
gene id: 1136231:CORT_0G01870
uniprot id: H8XAM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

1136231:CORT 0D04950
gene id: 1136231:CORT_0D04950
uniprot id: H8X687
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B05680
gene id: 1136231:CORT_0B05680
uniprot id: H8WZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1136231:CORT 0D02900
gene id: 1136231:CORT_0D02900
uniprot id: H8X542
names: Subcellular Location Annotation
messages: Nucleus membrane
messages: nuclear pore complex

1136231:CORT 0F00880
gene id: 1136231:CORT_0F00880
uniprot id: H8X919
names: Similarity
messages: Belongs to the peptidase A1 family.

1136231:CORT 0D03920
gene id: 1136231:CORT_0D03920
uniprot id: H8X5Y4
names: Similarity
messages: Belongs to the COG3 family.

1136231:CORT 0B01120
gene id: 1136231:CORT_0B01120
uniprot id: H8WZG4
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1136231:CORT 0F03170
gene id: 1136231:CORT_0F03170
uniprot id: H8X8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

1136231:CORT 0B00580
gene id: 1136231:CORT_0B00580
uniprot id: H8WZB1
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

1136231:CORT 0C05650
gene id: 1136231:CORT_0C05650
uniprot id: H8X379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1136231:CORT 0C03500
gene id: 1136231:CORT_0C03500
uniprot id: H8X3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

1136231:CORT 0A09200
gene id: 1136231:CORT_0A09200
uniprot id: H8WYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0D07540
gene id: 1136231:CORT_0D07540
uniprot id: H8X6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0B00250
gene id: 1136231:CORT_0B00250
uniprot id: H8WZ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

1136231:CORT 0E01740
gene id: 1136231:CORT_0E01740
uniprot id: H8X7H7
names: Subunit
messages: Homodimer.

1136231:CORT 0E00420
gene id: 1136231:CORT_0E00420
uniprot id: H8X6M1
names: Similarity
messages: Belongs to the CDC123 family.

1136231:CORT 0H00710
gene id: 1136231:CORT_0H00710
uniprot id: H8XBK0
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C03790
gene id: 1136231:CORT_0C03790
uniprot id: H8X3W6
names: Similarity
messages: Belongs to the peptidase M24B family.

1136231:CORT 0F01410
gene id: 1136231:CORT_0F01410
uniprot id: H8X969
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136231:CORT 0A08530
gene id: 1136231:CORT_0A08530
uniprot id: H8WYC2
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1136231:CORT 0B08000
gene id: 1136231:CORT_0B08000
uniprot id: H8X1U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

1136231:CORT 0B06750
gene id: 1136231:CORT_0B06750
uniprot id: H8X1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1136231:CORT 0E01470
gene id: 1136231:CORT_0E01470
uniprot id: H8X7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

1136231:CORT 0G00970
gene id: 1136231:CORT_0G00970
uniprot id: H8X9W8
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A01650
gene id: 1136231:CORT_0A01650
uniprot id: H8WVT3
names: Similarity
messages: Belongs to the NARF family.

1136231:CORT 0A10330
gene id: 1136231:CORT_0A10330
uniprot id: H8WXB3
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0C01490
gene id: 1136231:CORT_0C01490
uniprot id: H8X2H9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A03530
gene id: 1136231:CORT_0A03530
uniprot id: H8WWB7
names: Similarity
messages: Belongs to the PPase family.

1136231:CORT 0A09910
gene id: 1136231:CORT_0A09910
uniprot id: H8WX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1136231:CORT 0C05420
gene id: 1136231:CORT_0C05420
uniprot id: H8X356
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1136231:CORT 0E00350
gene id: 1136231:CORT_0E00350
uniprot id: H8X6L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

1136231:CORT 0F02830
gene id: 1136231:CORT_0F02830
uniprot id: H8X8N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.
messages: telomere

1136231:CORT 0C03400
gene id: 1136231:CORT_0C03400
uniprot id: H8X3S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

1136231:CORT 0D02660
gene id: 1136231:CORT_0D02660
uniprot id: H8X518
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1136231:CORT 0A04970
gene id: 1136231:CORT_0A04970
uniprot id: H8WXT8
names: Similarity
messages: Belongs to the protein kinase superfamily.

1136231:CORT 0H02460
gene id: 1136231:CORT_0H02460
uniprot id: H8XBA7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1136231:CORT 0A03080
gene id: 1136231:CORT_0A03080
uniprot id: H8WW73
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1136231:CORT 0D07020
gene id: 1136231:CORT_0D07020
uniprot id: H8X5S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1136231:CORT 0E01460
gene id: 1136231:CORT_0E01460
uniprot id: H8X7F0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.
messages: Prevacuolar compartment membrane
messages: multivesicular body membrane

1136231:CORT 0C07330
gene id: 1136231:CORT_0C07330
uniprot id: H8X4F1
names: Similarity
messages: Belongs to the peptidase S10 family.

1136231:CORT 0D02290
gene id: 1136231:CORT_0D02290
uniprot id: H8X4Y4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1136231:CORT 0A10670
gene id: 1136231:CORT_0A10670
uniprot id: H8WXE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1136231:CORT 0B08410
gene id: 1136231:CORT_0B08410
uniprot id: H8X035
names: Similarity
messages: Belongs to the NOP9 family.

1136231:CORT 0B05140
gene id: 1136231:CORT_0B05140
uniprot id: H8WZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

1136231:CORT 0D04560
gene id: 1136231:CORT_0D04560
uniprot id: H8X648
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

1136231:CORT 0G00140
gene id: 1136231:CORT_0G00140
uniprot id: H8X9N9
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0C03120
gene id: 1136231:CORT_0C03120
uniprot id: H8X3Q0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

1136231:CORT 0C06150
gene id: 1136231:CORT_0C06150
uniprot id: H8X436
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1136231:CORT 0A00650
gene id: 1136231:CORT_0A00650
uniprot id: H8WVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136231:CORT 0D05420
gene id: 1136231:CORT_0D05420
uniprot id: H8X6D3
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

1136231:CORT 0B06510
gene id: 1136231:CORT_0B06510
uniprot id: H8X015
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1136231:CORT 0C03540
gene id: 1136231:CORT_0C03540
uniprot id: H8X3U1
names: Similarity
messages: Belongs to the uridine kinase family.

1136231:CORT 0C04240
gene id: 1136231:CORT_0C04240
uniprot id: H8X409
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

1136231:CORT 0A01960
gene id: 1136231:CORT_0A01960
uniprot id: H8WVW3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1136231:CORT 0F03810
gene id: 1136231:CORT_0F03810
uniprot id: H8X9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

1136231:CORT 0B06110
gene id: 1136231:CORT_0B06110
uniprot id: H8WZX5
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1136231:CORT 0A03020
gene id: 1136231:CORT_0A03020
uniprot id: H8WW67
names: Similarity
messages: Belongs to the PIGH family.

1136231:CORT 0D01390
gene id: 1136231:CORT_0D01390
uniprot id: H8X4P6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1136231:CORT 0D06530
gene id: 1136231:CORT_0D06530
uniprot id: H8X5N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane

1136231:CORT 0C03260
gene id: 1136231:CORT_0C03260
uniprot id: H8X3R3
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

1136231:CORT 0G00950
gene id: 1136231:CORT_0G00950
uniprot id: H8X9W6
names: Similarity
messages: Belongs to the BRX1 family.

1136231:CORT 0B07180
gene id: 1136231:CORT_0B07180
uniprot id: H8X1M0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1136231:CORT 0B05500
gene id: 1136231:CORT_0B05500
uniprot id: H8WZR3
names: Similarity
messages: Belongs to the Cdt1 family.

1136231:CORT 0G01760
gene id: 1136231:CORT_0G01760
uniprot id: H8XAL1
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

1136231:CORT 0B05340
gene id: 1136231:CORT_0B05340
uniprot id: H8WZP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

1136231:CORT 0A12800
gene id: 1136231:CORT_0A12800
uniprot id: H8WZ32
names: Similarity
messages: Belongs to the HscB family.

1136231:CORT 0F00160
gene id: 1136231:CORT_0F00160
uniprot id: H8X8U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.
messages: Membrane

1136231:CORT 0A08950
gene id: 1136231:CORT_0A08950
uniprot id: H8WYG4
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0A03780
gene id: 1136231:CORT_0A03780
uniprot id: H8WWE2
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

1136231:CORT 0A02510
gene id: 1136231:CORT_0A02510
uniprot id: H8WW18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization.
messages: cytoskeleton

1136231:CORT 0C04020
gene id: 1136231:CORT_0C04020
uniprot id: H8X3Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

1136231:CORT 0A12890
gene id: 1136231:CORT_0A12890
uniprot id: H8WZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

1136231:CORT 0C04460
gene id: 1136231:CORT_0C04460
uniprot id: H8X2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAK10 family.
messages: Cytoplasm

1136231:CORT 0E01690
gene id: 1136231:CORT_0E01690
uniprot id: H8X7H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

1136231:CORT 0H00760
gene id: 1136231:CORT_0H00760
uniprot id: H8XBK5
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H01390
gene id: 1136231:CORT_0H01390
uniprot id: H8XB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136231:CORT 0E03570
gene id: 1136231:CORT_0E03570
uniprot id: H8X717
names: Subcellular Location Annotation
messages: cell wall

1136231:CORT 0C01240
gene id: 1136231:CORT_0C01240
uniprot id: H8X2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1136231:CORT 0A06260
gene id: 1136231:CORT_0A06260
uniprot id: H8WY65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

1136231:CORT 0A07250
gene id: 1136231:CORT_0A07250
uniprot id: H8WWX0
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0D06550
gene id: 1136231:CORT_0D06550
uniprot id: H8X5N1
names: Similarity
messages: Belongs to the RNase Z family.

1136231:CORT 0G00160
gene id: 1136231:CORT_0G00160
uniprot id: H8X9P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1136231:CORT 0D06780
gene id: 1136231:CORT_0D06780
uniprot id: H8X5Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: Nucleus
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

1136231:CORT 0C00920
gene id: 1136231:CORT_0C00920
uniprot id: H8X3J6
names: Similarity
messages: Belongs to the CAND family.

1136231:CORT 0A02520
gene id: 1136231:CORT_0A02520
uniprot id: H8WW19
names: Similarity
messages: Belongs to the peptidase S9B family.

1136231:CORT 0B00910
gene id: 1136231:CORT_0B00910
uniprot id: H8WZE3
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0D02230
gene id: 1136231:CORT_0D02230
uniprot id: H8X4X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

1136231:CORT 0B03110
gene id: 1136231:CORT_0B03110
uniprot id: H8X0Y3
names: Similarity
messages: Belongs to the glutaredoxin family.

1136231:CORT 0G01510
gene id: 1136231:CORT_0G01510
uniprot id: H8XAI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

1136231:CORT 0A10110
gene id: 1136231:CORT_0A10110
uniprot id: H8WX91
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1136231:CORT 0H00570
gene id: 1136231:CORT_0H00570
uniprot id: H8XBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

1136231:CORT 0A09700
gene id: 1136231:CORT_0A09700
uniprot id: H8WX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1136231:CORT 0E00220
gene id: 1136231:CORT_0E00220
uniprot id: H8X6K2
names: Similarity
messages: Belongs to the FGGY kinase family.

1136231:CORT 0D02680
gene id: 1136231:CORT_0D02680
uniprot id: H8X520
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

1136231:CORT 0A11520
gene id: 1136231:CORT_0A11520
uniprot id: H8WYQ5
names: Similarity
messages: Belongs to the oxoprolinase family.

1136231:CORT 0B00570
gene id: 1136231:CORT_0B00570
uniprot id: H8WZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1136231:CORT 0F00660
gene id: 1136231:CORT_0F00660
uniprot id: H8X8Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1136231:CORT 0F03260
gene id: 1136231:CORT_0F03260
uniprot id: H8X8S5
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

1136231:CORT 0B04490
gene id: 1136231:CORT_0B04490
uniprot id: H8X1B7
names: Similarity
messages: Belongs to the OPA3 family.

1136231:CORT 0E00370
gene id: 1136231:CORT_0E00370
uniprot id: H8X6L6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

1136231:CORT 0B09510
gene id: 1136231:CORT_0B09510
uniprot id: H8X0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1136231:CORT 0F00470
gene id: 1136231:CORT_0F00470
uniprot id: H8X8X8
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

1136231:CORT 0H01140
gene id: 1136231:CORT_0H01140
uniprot id: H8XAY2
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0H02330
gene id: 1136231:CORT_0H02330
uniprot id: H8XB94
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1136231:CORT 0C05000
gene id: 1136231:CORT_0C05000
uniprot id: H8X314
names: Similarity
messages: Belongs to the Rho GDI family.

1136231:CORT 0B03030
gene id: 1136231:CORT_0B03030
uniprot id: H8X0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1136231:CORT 0E06420
gene id: 1136231:CORT_0E06420
uniprot id: H8X8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

1136231:CORT 0H00200
gene id: 1136231:CORT_0H00200
uniprot id: H8XBF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

1136231:CORT 0C05230
gene id: 1136231:CORT_0C05230
uniprot id: H8X337
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

1136231:CORT 0F04490
gene id: 1136231:CORT_0F04490
uniprot id: H8X9K7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Mitochondrion matrix

1136231:CORT 0E02560
gene id: 1136231:CORT_0E02560
uniprot id: H8X7Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.

1136231:CORT 0D02210
gene id: 1136231:CORT_0D02210
uniprot id: H8X4X6
names: Similarity
messages: Belongs to the actin family.

1136231:CORT 0B10250
gene id: 1136231:CORT_0B10250
uniprot id: H8X208
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1136231:CORT 0G01730
gene id: 1136231:CORT_0G01730
uniprot id: H8XAK9
names: Similarity
messages: Belongs to the peptidase S10 family.

1136231:CORT 0C02860
gene id: 1136231:CORT_0C02860
uniprot id: H8X3M4
names: Cofactor
messages: Divalent metal ions. Mg(2+) is the most effective.

1136231:CORT 0D02280
gene id: 1136231:CORT_0D02280
uniprot id: H8X4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

1136231:CORT 0H01750
gene id: 1136231:CORT_0H01750
uniprot id: H8XB39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

1136231:CORT 0A07050
gene id: 1136231:CORT_0A07050
uniprot id: H8WWV0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1136231:CORT 0C06800
gene id: 1136231:CORT_0C06800
uniprot id: H8X4A0
names: Similarity
messages: Belongs to the peptidase C19 family.

1136231:CORT 0A11900
gene id: 1136231:CORT_0A11900
uniprot id: H8WYU3
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

1136231:CORT 0B00650
gene id: 1136231:CORT_0B00650
uniprot id: H8WZB8
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

1136231:CORT 0D05020
gene id: 1136231:CORT_0D05020
uniprot id: H8X694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD3 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1136231:CORT 0D02850
gene id: 1136231:CORT_0D02850
uniprot id: H8X537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

1136231:CORT 0D00540
gene id: 1136231:CORT_0D00540
uniprot id: H8X4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
messages: cis-Golgi network

1136231:CORT 0B02050
gene id: 1136231:CORT_0B02050
uniprot id: H8X0N4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1136231:CORT 0C06840
gene id: 1136231:CORT_0C06840
uniprot id: H8X4A4
names: Similarity
messages: Belongs to the phosducin family.

1136231:CORT 0D04590
gene id: 1136231:CORT_0D04590
uniprot id: H8X651
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

1136231:CORT 0E04370
gene id: 1136231:CORT_0E04370
uniprot id: H8X795
names: Subcellular Location Annotation
messages: Nucleus

1136231:CORT 0A02420
gene id: 1136231:CORT_0A02420
uniprot id: H8WW09
names: Subcellular Location Annotation
messages: Membrane

1136231:CORT 0B01750
gene id: 1136231:CORT_0B01750
uniprot id: H8X0K4
names: Subcellular Location Annotation
messages: Nucleus