11234:MeVgp6
gene id: 11234:MeVgp6
uniprot id: Q784S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the paramyxovirus L protein family.
messages: Cytoplasm
messages: Host cytoplasm
messages: Interacts with the P protein.
messages: RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The replicase mode is dependent on intracellular N protein concentration. In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
messages: RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymerase binds to the genomic RNA at the 3' leader promoter, and transcribes subsequently all viral mRNAs with a decreasing efficiency. The first gene is the most transcribed, and the last the least transcribed. The viral phosphoprotein acts as a processivity factor. Capping is concommitant with initiation of mRNA transcription. Indeed, a GDP polyribonucleotidyl transferase (PRNTase) adds the cap structure when the nascent RNA chain length has reached few nucleotides. Ribose 2'-O methylation of viral mRNA cap precedes and facilitates subsequent guanine-N-7 methylation, both activities being carried by the viral polymerase. Polyadenylation of mRNAs occur by a stuttering mechanism at a slipery stop site present at the end viral genes. After finishing transcription of a mRNA, the polymerase can resume transcription of the downstream gene.
messages: Virion

11234:MeVgp5
gene id: 11234:MeVgp5
uniprot id: Q9YIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paramyxoviruses hemagglutinin-neuraminidase family. Non-sialidase subfamily.
messages: Membrane
messages: Virion membrane

11234:MeVgp4
gene id: 11234:MeVgp4
uniprot id: Q784S2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the paramyxoviruses fusion glycoprotein family.
messages: Cell membrane
messages: Homotrimer of disulfide-linked F1-F2.
messages: Host cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Virion membrane

11234:MeVgp2
gene id: 11234:MeVgp2
uniprot id: A0A348GSU1
uniprot id: A9YTL6
names: Function
names: Similarity
messages: Belongs to the morbillivirus P protein family.
messages: Belongs to the morbillivirus protein C family.
messages: Essential component of the RNA polymerase and the nascent chain assembly complex. Also required during RNA synthesis.

11234:MeVgp1
gene id: 11234:MeVgp1
uniprot id: Q784S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the paramyxoviruses nucleocapsid family.
messages: Encapsidates the genome, protecting it from nucleases.
messages: Homomultimerizes to form the nucleocapsid. Binds to viral genomic RNA. In nucleocapsid, binds the P protein and thereby positions the polymerase on the template.
messages: Host cytoplasm
messages: Virion

11234:MeVgp3
gene id: 11234:MeVgp3
uniprot id: Q786M4
names: Function
names: Subcellular Location Annotation
messages: The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
messages: Virion