1123366:TH3 RS16735
gene id: 1123366:TH3_RS16735
uniprot id: A0A0B4Y450
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1123366:TH3 RS19860
gene id: 1123366:TH3_RS19860
uniprot id: A0A0B4Y3N4
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1123366:TH3 RS09595
gene id: 1123366:TH3_RS09595
uniprot id: A0A0B4Y0G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1123366:TH3 RS01435
gene id: 1123366:TH3_RS01435
uniprot id: A0A0B4XUK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1123366:TH3 RS08710
gene id: 1123366:TH3_RS08710
uniprot id: A0A0B4XYB4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1123366:TH3 RS21075
gene id: 1123366:TH3_RS21075
uniprot id: A0A0B4Y6P0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1123366:TH3 RS13620
gene id: 1123366:TH3_RS13620
uniprot id: A0A0B4XX54
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS10300
gene id: 1123366:TH3_RS10300
uniprot id: A0A0B4Y0S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1123366:TH3 RS01360
gene id: 1123366:TH3_RS01360
uniprot id: A0A0B4XUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1123366:TH3 RS12520
gene id: 1123366:TH3_RS12520
uniprot id: A0A0B4Y1S0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1123366:TH3 RS02710
gene id: 1123366:TH3_RS02710
uniprot id: A0A0B4XWF2
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1123366:TH3 RS01630
gene id: 1123366:TH3_RS01630
uniprot id: A0A0B4XQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS17580
gene id: 1123366:TH3_RS17580
uniprot id: A0A0B4Y2X2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1123366:TH3 RS06175
gene id: 1123366:TH3_RS06175
uniprot id: A0A0B4XSQ9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1123366:TH3 RS06740
gene id: 1123366:TH3_RS06740
uniprot id: A0A0B4XYT0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1123366:TH3 RS01900
gene id: 1123366:TH3_RS01900
uniprot id: A0A0B4XUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1123366:TH3 RS17515
gene id: 1123366:TH3_RS17515
uniprot id: A0A0B4Y4L5
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1123366:TH3 RS13705
gene id: 1123366:TH3_RS13705
uniprot id: A0A0B4Y022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS19920
gene id: 1123366:TH3_RS19920
uniprot id: A0A0B4Y5V0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1123366:TH3 RS03030
gene id: 1123366:TH3_RS03030
uniprot id: A0A0B4XVB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1123366:TH3 RS09300
gene id: 1123366:TH3_RS09300
uniprot id: A0A0B4XXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS18285
gene id: 1123366:TH3_RS18285
uniprot id: A0A0B4Y2M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1123366:TH3 RS19645
gene id: 1123366:TH3_RS19645
uniprot id: A0A0B4Y470
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123366:TH3 RS08180
gene id: 1123366:TH3_RS08180
uniprot id: A0A0B4XXZ7
names: Similarity
messages: Belongs to the MotB family.

1123366:TH3 RS05805
gene id: 1123366:TH3_RS05805
uniprot id: A0A0B4XXV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS00930
gene id: 1123366:TH3_RS00930
uniprot id: A0A0B4XPM9
names: Similarity
messages: Belongs to the GSP E family.

1123366:TH3 RS13415
gene id: 1123366:TH3_RS13415
uniprot id: A0A0B4XX19
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1123366:TH3 RS12305
gene id: 1123366:TH3_RS12305
uniprot id: A0A0B4XZB1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1123366:TH3 RS14720
gene id: 1123366:TH3_RS14720
uniprot id: A0A0B4Y351
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS03320
gene id: 1123366:TH3_RS03320
uniprot id: A0A0B4XWF9
names: Subunit
messages: Homotetramer.

1123366:TH3 RS20260
gene id: 1123366:TH3_RS20260
uniprot id: A0A0B4Y4I2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS01810
gene id: 1123366:TH3_RS01810
uniprot id: A0A0B4XTE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS08865
gene id: 1123366:TH3_RS08865
uniprot id: A0A0B4XXJ1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1123366:TH3 RS09525
gene id: 1123366:TH3_RS09525
uniprot id: A0A0B4XZZ7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS12100
gene id: 1123366:TH3_RS12100
uniprot id: A0A0B4XZ75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1123366:TH3 RS14185
gene id: 1123366:TH3_RS14185
uniprot id: A0A0B4XXI0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1123366:TH3 RS02970
gene id: 1123366:TH3_RS02970
uniprot id: A0A0B4XW72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS00460
gene id: 1123366:TH3_RS00460
uniprot id: A0A0B4XPB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1123366:TH3 RS09775
gene id: 1123366:TH3_RS09775
uniprot id: A0A0B4Y045
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1123366:TH3 RS08020
gene id: 1123366:TH3_RS08020
uniprot id: A0A0B4XX14
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1123366:TH3 RS16620
gene id: 1123366:TH3_RS16620
uniprot id: A0A0B4XYS1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1123366:TH3 RS18300
gene id: 1123366:TH3_RS18300
uniprot id: A0A0B4XZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS03585
gene id: 1123366:TH3_RS03585
uniprot id: A0A0B4XVK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1123366:TH3 RS11500
gene id: 1123366:TH3_RS11500
uniprot id: A0A0B4XZS6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS10755
gene id: 1123366:TH3_RS10755
uniprot id: A0A0B4XYG1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1123366:TH3 RS16820
gene id: 1123366:TH3_RS16820
uniprot id: A0A0B4XYX2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS19805
gene id: 1123366:TH3_RS19805
uniprot id: A0A0B4Y3M4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123366:TH3 RS03200
gene id: 1123366:TH3_RS03200
uniprot id: A0A0B4XQZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1123366:TH3 RS10600
gene id: 1123366:TH3_RS10600
uniprot id: A0A0B4Y0K4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1123366:TH3 RS18695
gene id: 1123366:TH3_RS18695
uniprot id: A0A0B4Y021
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1123366:TH3 RS20525
gene id: 1123366:TH3_RS20525
uniprot id: A0A0B4Y6B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1123366:TH3 RS22560
gene id: 1123366:TH3_RS22560
uniprot id: A0A0B4Y5P7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1123366:TH3 RS03740
gene id: 1123366:TH3_RS03740
uniprot id: A0A0B4XUC7
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1123366:TH3 RS12435
gene id: 1123366:TH3_RS12435
uniprot id: A0A0B4XZD3
names: Similarity
messages: Belongs to the YicC/YloC family.

1123366:TH3 RS17120
gene id: 1123366:TH3_RS17120
uniprot id: A0A0B4XZ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1123366:TH3 RS12535
gene id: 1123366:TH3_RS12535
uniprot id: A0A0B4XZF4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS21145
gene id: 1123366:TH3_RS21145
uniprot id: A0A0B4Y510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1123366:TH3 RS06710
gene id: 1123366:TH3_RS06710
uniprot id: A0A0B4XWD4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS11850
gene id: 1123366:TH3_RS11850
uniprot id: A0A0B4Y1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS01335
gene id: 1123366:TH3_RS01335
uniprot id: A0A0B4XUI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1123366:TH3 RS09570
gene id: 1123366:TH3_RS09570
uniprot id: A0A0B4Y0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS18945
gene id: 1123366:TH3_RS18945
uniprot id: A0A0B4Y084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS19150
gene id: 1123366:TH3_RS19150
uniprot id: A0A0B4Y0C6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS10445
gene id: 1123366:TH3_RS10445
uniprot id: A0A0B4XYC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1123366:TH3 RS07200
gene id: 1123366:TH3_RS07200
uniprot id: A0A0B4XXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1123366:TH3 RS13840
gene id: 1123366:TH3_RS13840
uniprot id: A0A0B4Y2K4
names: Similarity
messages: Belongs to the FGGY kinase family.

1123366:TH3 RS20515
gene id: 1123366:TH3_RS20515
uniprot id: A0A0B4Y4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1123366:TH3 RS08925
gene id: 1123366:TH3_RS08925
uniprot id: A0A0B4XZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS07925
gene id: 1123366:TH3_RS07925
uniprot id: A0A0B4XZE7
names: Similarity
messages: Belongs to the pyruvate kinase family.

1123366:TH3 RS07800
gene id: 1123366:TH3_RS07800
uniprot id: A0A0B4XTR6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1123366:TH3 RS03900
gene id: 1123366:TH3_RS03900
uniprot id: A0A0B4XWU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1123366:TH3 RS22320
gene id: 1123366:TH3_RS22320
uniprot id: A0A0B4XYR1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS19930
gene id: 1123366:TH3_RS19930
uniprot id: A0A0B4Y4B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1123366:TH3 RS15380
gene id: 1123366:TH3_RS15380
uniprot id: A0A0B4Y3G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1123366:TH3 RS18685
gene id: 1123366:TH3_RS18685
uniprot id: A0A0B4Y564
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1123366:TH3 RS15290
gene id: 1123366:TH3_RS15290
uniprot id: A0A0B4XY44
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1123366:TH3 RS06520
gene id: 1123366:TH3_RS06520
uniprot id: A0A0B4XYC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1123366:TH3 RS01180
gene id: 1123366:TH3_RS01180
uniprot id: A0A0B4XUG8
names: Similarity
messages: Belongs to the Gfa family.

1123366:TH3 RS19595
gene id: 1123366:TH3_RS19595
uniprot id: A0A0B4Y463
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1123366:TH3 RS17955
gene id: 1123366:TH3_RS17955
uniprot id: A0A0B4Y336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1123366:TH3 RS08430
gene id: 1123366:TH3_RS08430
uniprot id: A0A0B4XY53
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1123366:TH3 RS19200
gene id: 1123366:TH3_RS19200
uniprot id: A0A0B4Y5I5
names: Similarity
messages: Belongs to the PRORSD1 family.

1123366:TH3 RS16680
gene id: 1123366:TH3_RS16680
uniprot id: A0A0B4Y1R4
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1123366:TH3 RS13805
gene id: 1123366:TH3_RS13805
uniprot id: A0A0B4Y120
names: Similarity
messages: Belongs to the DapA family.

1123366:TH3 RS08005
gene id: 1123366:TH3_RS08005
uniprot id: A0A0B4XZ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1123366:TH3 RS13565
gene id: 1123366:TH3_RS13565
uniprot id: A0A0B4Y2B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS16785
gene id: 1123366:TH3_RS16785
uniprot id: A0A0B4Y461
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1123366:TH3 RS17900
gene id: 1123366:TH3_RS17900
uniprot id: A0A0B4XZL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS12420
gene id: 1123366:TH3_RS12420
uniprot id: A0A0B4Y1P9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1123366:TH3 RS19915
gene id: 1123366:TH3_RS19915
uniprot id: A0A0B4Y5Y9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1123366:TH3 RS05190
gene id: 1123366:TH3_RS05190
uniprot id: A0A0B4XS29
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS19045
gene id: 1123366:TH3_RS19045
uniprot id: A0A0B4Y5B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1123366:TH3 RS16780
gene id: 1123366:TH3_RS16780
uniprot id: A0A0B4Y1U3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1123366:TH3 RS16500
gene id: 1123366:TH3_RS16500
uniprot id: A0A0B4Y416
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1123366:TH3 RS02805
gene id: 1123366:TH3_RS02805
uniprot id: A0A0B4XQQ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123366:TH3 RS08495
gene id: 1123366:TH3_RS08495
uniprot id: A0A0B4XZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1123366:TH3 RS13945
gene id: 1123366:TH3_RS13945
uniprot id: A0A0B4Y2M8
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1123366:TH3 RS09730
gene id: 1123366:TH3_RS09730
uniprot id: A0A0B4XUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS20695
gene id: 1123366:TH3_RS20695
uniprot id: A0A0B4Y437
names: Similarity
messages: Belongs to the PhoH family.

1123366:TH3 RS17845
gene id: 1123366:TH3_RS17845
uniprot id: A0A0B4Y4N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1123366:TH3 RS01870
gene id: 1123366:TH3_RS01870
uniprot id: A0A0B4XQ97
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1123366:TH3 RS11065
gene id: 1123366:TH3_RS11065
uniprot id: A0A0B4Y0W6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

1123366:TH3 RS00945
gene id: 1123366:TH3_RS00945
uniprot id: A0A0B4XVM2
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1123366:TH3 RS10650
gene id: 1123366:TH3_RS10650
uniprot id: A0A0B4Y0L6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS01470
gene id: 1123366:TH3_RS01470
uniprot id: A0A0B4XVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1123366:TH3 RS11900
gene id: 1123366:TH3_RS11900
uniprot id: A0A0B4Y1L9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1123366:TH3 RS10595
gene id: 1123366:TH3_RS10595
uniprot id: A0A0B4Y0X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1123366:TH3 RS18345
gene id: 1123366:TH3_RS18345
uniprot id: A0A0B4Y4W7
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1123366:TH3 RS07190
gene id: 1123366:TH3_RS07190
uniprot id: A0A0B4XYR4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1123366:TH3 RS17705
gene id: 1123366:TH3_RS17705
uniprot id: A0A0B4Y2Z1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1123366:TH3 RS16715
gene id: 1123366:TH3_RS16715
uniprot id: A0A0B4Y453
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

1123366:TH3 RS06860
gene id: 1123366:TH3_RS06860
uniprot id: A0A0B4XWG1
names: Similarity
messages: Belongs to the universal stress protein A family.

1123366:TH3 RS05520
gene id: 1123366:TH3_RS05520
uniprot id: A0A0B4XY26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1123366:TH3 RS02565
gene id: 1123366:TH3_RS02565
uniprot id: A0A0B4XVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS11250
gene id: 1123366:TH3_RS11250
uniprot id: A0A0B4XZM9
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS06115
gene id: 1123366:TH3_RS06115
uniprot id: A0A0B4XYC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1123366:TH3 RS13050
gene id: 1123366:TH3_RS13050
uniprot id: A0A0B4Y0K1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1123366:TH3 RS00625
gene id: 1123366:TH3_RS00625
uniprot id: A0A0B4XVF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1123366:TH3 RS07320
gene id: 1123366:TH3_RS07320
uniprot id: A0A0B4XXI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS13595
gene id: 1123366:TH3_RS13595
uniprot id: A0A0B4XX50
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1123366:TH3 RS12625
gene id: 1123366:TH3_RS12625
uniprot id: A0A0B4XWN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1123366:TH3 RS01155
gene id: 1123366:TH3_RS01155
uniprot id: A0A0B4XUG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1123366:TH3 RS20095
gene id: 1123366:TH3_RS20095
uniprot id: A0A0B4Y629
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS19575
gene id: 1123366:TH3_RS19575
uniprot id: A0A0B4Y3J1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1123366:TH3 RS14745
gene id: 1123366:TH3_RS14745
uniprot id: A0A0B4Y354
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1123366:TH3 RS13260
gene id: 1123366:TH3_RS13260
uniprot id: A0A0B4Y290
names: Function
messages: Multidrug efflux pump.

1123366:TH3 RS14790
gene id: 1123366:TH3_RS14790
uniprot id: A0A0B4Y1K1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS21040
gene id: 1123366:TH3_RS21040
uniprot id: A0A0B4Y4Y5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1123366:TH3 RS09360
gene id: 1123366:TH3_RS09360
uniprot id: A0A0B4XZX8
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS02225
gene id: 1123366:TH3_RS02225
uniprot id: A0A0B4XW84
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS20740
gene id: 1123366:TH3_RS20740
uniprot id: A0A0B4Y4S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS16105
gene id: 1123366:TH3_RS16105
uniprot id: A0A0B4XYI4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS07380
gene id: 1123366:TH3_RS07380
uniprot id: A0A0B4XZ39
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1123366:TH3 RS15915
gene id: 1123366:TH3_RS15915
uniprot id: A0A0B4Y200
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS14985
gene id: 1123366:TH3_RS14985
uniprot id: A0A0B4XXZ2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1123366:TH3 RS01620
gene id: 1123366:TH3_RS01620
uniprot id: A0A0B4XW08
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS22265
gene id: 1123366:TH3_RS22265
uniprot id: A0A0B4XW25
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS03760
gene id: 1123366:TH3_RS03760
uniprot id: A0A0B4XVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1123366:TH3 RS16465
gene id: 1123366:TH3_RS16465
uniprot id: A0A0B4Y295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS21070
gene id: 1123366:TH3_RS21070
uniprot id: A0A0B4Y4A9
names: Similarity
messages: Belongs to the SCO1/2 family.

1123366:TH3 RS18590
gene id: 1123366:TH3_RS18590
uniprot id: A0A0B4Y516
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS20800
gene id: 1123366:TH3_RS20800
uniprot id: A0A0B4Y6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1123366:TH3 RS10625
gene id: 1123366:TH3_RS10625
uniprot id: A0A0B4Y0L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS14545
gene id: 1123366:TH3_RS14545
uniprot id: A0A0B4Y0K7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS10160
gene id: 1123366:TH3_RS10160
uniprot id: A0A0B4Y0B6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS05995
gene id: 1123366:TH3_RS05995
uniprot id: A0A0B4XY99
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1123366:TH3 RS05240
gene id: 1123366:TH3_RS05240
uniprot id: A0A0B4XS41
names: Similarity
messages: Belongs to the GST superfamily.

1123366:TH3 RS11780
gene id: 1123366:TH3_RS11780
uniprot id: A0A0B4Y1E3
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1123366:TH3 RS00140
gene id: 1123366:TH3_RS00140
uniprot id: A0A0B4XTY3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS01200
gene id: 1123366:TH3_RS01200
uniprot id: A0A0B4XPU2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS13955
gene id: 1123366:TH3_RS13955
uniprot id: A0A0B4XXC6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1123366:TH3 RS03215
gene id: 1123366:TH3_RS03215
uniprot id: A0A0B4XWQ9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1123366:TH3 RS18515
gene id: 1123366:TH3_RS18515
uniprot id: A0A0B4Y527
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1123366:TH3 RS20790
gene id: 1123366:TH3_RS20790
uniprot id: A0A0B4Y4T9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1123366:TH3 RS02675
gene id: 1123366:TH3_RS02675
uniprot id: A0A0B4XV53
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS20390
gene id: 1123366:TH3_RS20390
uniprot id: A0A0B4Y3Y4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1123366:TH3 RS22230
gene id: 1123366:TH3_RS22230
uniprot id: A0A0B4XX33
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1123366:TH3 RS11145
gene id: 1123366:TH3_RS11145
uniprot id: A0A0B4XVP6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

1123366:TH3 RS19405
gene id: 1123366:TH3_RS19405
uniprot id: A0A0B4Y5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1123366:TH3 RS07170
gene id: 1123366:TH3_RS07170
uniprot id: A0A0B4XTD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1123366:TH3 RS02335
gene id: 1123366:TH3_RS02335
uniprot id: A0A0B4XVU2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS00615
gene id: 1123366:TH3_RS00615
uniprot id: A0A0B4XU87
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS20870
gene id: 1123366:TH3_RS20870
uniprot id: A0A0B4Y471
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1123366:TH3 RS16295
gene id: 1123366:TH3_RS16295
uniprot id: A0A0B4Y1F5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1123366:TH3 RS09235
gene id: 1123366:TH3_RS09235
uniprot id: A0A0B4XZW2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS05010
gene id: 1123366:TH3_RS05010
uniprot id: A0A0B4XXD7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS13795
gene id: 1123366:TH3_RS13795
uniprot id: A0A0B4Y2G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS14990
gene id: 1123366:TH3_RS14990
uniprot id: A0A0B4Y1M6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS16730
gene id: 1123366:TH3_RS16730
uniprot id: A0A0B4Y1T0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS03470
gene id: 1123366:TH3_RS03470
uniprot id: A0A0B4XWW0
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1123366:TH3 RS05450
gene id: 1123366:TH3_RS05450
uniprot id: A0A0B4XWF5
names: Similarity
messages: Belongs to the MreC family.

1123366:TH3 RS05265
gene id: 1123366:TH3_RS05265
uniprot id: A0A0B4XS48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1123366:TH3 RS10815
gene id: 1123366:TH3_RS10815
uniprot id: A0A0B4Y109
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.

1123366:TH3 RS00075
gene id: 1123366:TH3_RS00075
uniprot id: A0A0B4XV50
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1123366:TH3 RS04685
gene id: 1123366:TH3_RS04685
uniprot id: A0A0B4XW30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS19035
gene id: 1123366:TH3_RS19035
uniprot id: A0A0B4Y350
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS13310
gene id: 1123366:TH3_RS13310
uniprot id: A0A0B4Y299
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1123366:TH3 RS08155
gene id: 1123366:TH3_RS08155
uniprot id: A0A0B4XXZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1123366:TH3 RS16930
gene id: 1123366:TH3_RS16930
uniprot id: A0A0B4Y1Y2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1123366:TH3 RS08830
gene id: 1123366:TH3_RS08830
uniprot id: A0A0B4XUB3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS14330
gene id: 1123366:TH3_RS14330
uniprot id: A0A0B4Y2V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1123366:TH3 RS06800
gene id: 1123366:TH3_RS06800
uniprot id: A0A0B4XT81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS04925
gene id: 1123366:TH3_RS04925
uniprot id: A0A0B4XV46
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1123366:TH3 RS14505
gene id: 1123366:TH3_RS14505
uniprot id: A0A0B4XXS7
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS16380
gene id: 1123366:TH3_RS16380
uniprot id: A0A0B4Y3X6
names: Similarity
messages: Belongs to the GcvT family.

1123366:TH3 RS19820
gene id: 1123366:TH3_RS19820
uniprot id: A0A0B4Y0U3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS01985
gene id: 1123366:TH3_RS01985
uniprot id: A0A0B4XW61
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1123366:TH3 RS14840
gene id: 1123366:TH3_RS14840
uniprot id: A0A0B4Y1K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS16165
gene id: 1123366:TH3_RS16165
uniprot id: A0A0B4Y1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1123366:TH3 RS20025
gene id: 1123366:TH3_RS20025
uniprot id: A0A0B4Y0X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1123366:TH3 RS20545
gene id: 1123366:TH3_RS20545
uniprot id: A0A0B4Y413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1123366:TH3 RS10115
gene id: 1123366:TH3_RS10115
uniprot id: A0A0B4XV31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1123366:TH3 RS01965
gene id: 1123366:TH3_RS01965
uniprot id: A0A0B4XVN6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS02300
gene id: 1123366:TH3_RS02300
uniprot id: A0A0B4XTN8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1123366:TH3 RS10890
gene id: 1123366:TH3_RS10890
uniprot id: A0A0B4Y0S0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1123366:TH3 RS02125
gene id: 1123366:TH3_RS02125
uniprot id: A0A0B4XTK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS02480
gene id: 1123366:TH3_RS02480
uniprot id: A0A0B4XTQ8
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1123366:TH3 RS03315
gene id: 1123366:TH3_RS03315
uniprot id: A0A0B4XWS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1123366:TH3 RS16240
gene id: 1123366:TH3_RS16240
uniprot id: A0A0B4Y1E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS22730
gene id: 1123366:TH3_RS22730
uniprot id: A0A0B4Y6H8
names: Similarity
messages: Belongs to the UPF0260 family.

1123366:TH3 RS12600
gene id: 1123366:TH3_RS12600
uniprot id: A0A0B4XWM7
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

1123366:TH3 RS11150
gene id: 1123366:TH3_RS11150
uniprot id: A0A0B4XZL5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1123366:TH3 RS15400
gene id: 1123366:TH3_RS15400
uniprot id: A0A0B4Y102
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS16595
gene id: 1123366:TH3_RS16595
uniprot id: A0A0B4Y2B5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS09180
gene id: 1123366:TH3_RS09180
uniprot id: A0A0B4XZV1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS06355
gene id: 1123366:TH3_RS06355
uniprot id: A0A0B4XWY5
names: Similarity
messages: Belongs to the MEMO1 family.

1123366:TH3 RS13265
gene id: 1123366:TH3_RS13265
uniprot id: A0A0B4Y261
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1123366:TH3 RS10515
gene id: 1123366:TH3_RS10515
uniprot id: A0A0B4XYD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS02570
gene id: 1123366:TH3_RS02570
uniprot id: A0A0B4XQL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS10060
gene id: 1123366:TH3_RS10060
uniprot id: A0A0B4Y097
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1123366:TH3 RS07330
gene id: 1123366:TH3_RS07330
uniprot id: A0A0B4XZ30
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1123366:TH3 RS16645
gene id: 1123366:TH3_RS16645
uniprot id: A0A0B4XYS6
names: Similarity
messages: Belongs to the Dps family.

1123366:TH3 RS15445
gene id: 1123366:TH3_RS15445
uniprot id: A0A0B4Y3G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1123366:TH3 RS00740
gene id: 1123366:TH3_RS00740
uniprot id: A0A0B4XPI7
names: Function
messages: Multidrug efflux pump.

1123366:TH3 RS12510
gene id: 1123366:TH3_RS12510
uniprot id: A0A0B4XZE8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1123366:TH3 RS23390
gene id: 1123366:TH3_RS23390
uniprot id: A0A0B4XSV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1123366:TH3 RS15105
gene id: 1123366:TH3_RS15105
uniprot id: A0A0B4Y380
names: Similarity
messages: Belongs to the GST superfamily.

1123366:TH3 RS15005
gene id: 1123366:TH3_RS15005
uniprot id: A0A0B4Y362
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1123366:TH3 RS17870
gene id: 1123366:TH3_RS17870
uniprot id: A0A0B4Y4N7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS08185
gene id: 1123366:TH3_RS08185
uniprot id: A0A0B4XX41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1123366:TH3 RS09185
gene id: 1123366:TH3_RS09185
uniprot id: A0A0B4XUL1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1123366:TH3 RS15435
gene id: 1123366:TH3_RS15435
uniprot id: A0A0B4Y1T3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1123366:TH3 RS10845
gene id: 1123366:TH3_RS10845
uniprot id: A0A0B4XVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS09260
gene id: 1123366:TH3_RS09260
uniprot id: A0A0B4XUL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

1123366:TH3 RS06040
gene id: 1123366:TH3_RS06040
uniprot id: A0A0B4XYA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1123366:TH3 RS09110
gene id: 1123366:TH3_RS09110
uniprot id: A0A0B4XYI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS20785
gene id: 1123366:TH3_RS20785
uniprot id: A0A0B4Y1A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1123366:TH3 RS18480
gene id: 1123366:TH3_RS18480
uniprot id: A0A0B4Y3D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1123366:TH3 RS16435
gene id: 1123366:TH3_RS16435
uniprot id: A0A0B4XYP2
names: Similarity
messages: Belongs to the Ahb/Nir family.

1123366:TH3 RS17505
gene id: 1123366:TH3_RS17505
uniprot id: A0A0B4Y2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS01120
gene id: 1123366:TH3_RS01120
uniprot id: A0A0B4XV52
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

1123366:TH3 RS12500
gene id: 1123366:TH3_RS12500
uniprot id: A0A0B4XWK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1123366:TH3 RS03115
gene id: 1123366:TH3_RS03115
uniprot id: A0A0B4XWN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1123366:TH3 RS20340
gene id: 1123366:TH3_RS20340
uniprot id: A0A0B4Y3X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1123366:TH3 RS02895
gene id: 1123366:TH3_RS02895
uniprot id: A0A0B4XTX1
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS09305
gene id: 1123366:TH3_RS09305
uniprot id: A0A0B4Y0D0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1123366:TH3 RS10710
gene id: 1123366:TH3_RS10710
uniprot id: A0A0B4XZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123366:TH3 RS11960
gene id: 1123366:TH3_RS11960
uniprot id: A0A0B4Y1G5
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1123366:TH3 RS00540
gene id: 1123366:TH3_RS00540
uniprot id: A0A0B4XU67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1123366:TH3 RS02930
gene id: 1123366:TH3_RS02930
uniprot id: A0A0B4XQU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1123366:TH3 RS19225
gene id: 1123366:TH3_RS19225
uniprot id: A0A0B4Y5J2
names: Similarity
messages: Belongs to the OmpW/AlkL family.

1123366:TH3 RS03980
gene id: 1123366:TH3_RS03980
uniprot id: A0A0B4XWW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1123366:TH3 RS19360
gene id: 1123366:TH3_RS19360
uniprot id: A0A0B4Y0H5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1123366:TH3 RS12315
gene id: 1123366:TH3_RS12315
uniprot id: A0A0B4Y1M5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1123366:TH3 RS13605
gene id: 1123366:TH3_RS13605
uniprot id: A0A0B4Y001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS16115
gene id: 1123366:TH3_RS16115
uniprot id: A0A0B4Y1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS12515
gene id: 1123366:TH3_RS12515
uniprot id: A0A0B4Y1V4
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS05445
gene id: 1123366:TH3_RS05445
uniprot id: A0A0B4XS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1123366:TH3 RS16415
gene id: 1123366:TH3_RS16415
uniprot id: A0A0B4Y286
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1123366:TH3 RS15305
gene id: 1123366:TH3_RS15305
uniprot id: A0A0B4Y3F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1123366:TH3 RS12645
gene id: 1123366:TH3_RS12645
uniprot id: A0A0B4Y1U5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS06100
gene id: 1123366:TH3_RS06100
uniprot id: A0A0B4XSP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1123366:TH3 RS16705
gene id: 1123366:TH3_RS16705
uniprot id: A0A0B4Y1S2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS17440
gene id: 1123366:TH3_RS17440
uniprot id: A0A0B4Y4K2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS01020
gene id: 1123366:TH3_RS01020
uniprot id: A0A0B4XV27
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS15330
gene id: 1123366:TH3_RS15330
uniprot id: A0A0B4Y3F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1123366:TH3 RS06170
gene id: 1123366:TH3_RS06170
uniprot id: A0A0B4XY42
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1123366:TH3 RS16675
gene id: 1123366:TH3_RS16675
uniprot id: A0A0B4Y2C8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS10395
gene id: 1123366:TH3_RS10395
uniprot id: A0A0B4XYB3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1123366:TH3 RS16745
gene id: 1123366:TH3_RS16745
uniprot id: A0A0B4XYU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1123366:TH3 RS16040
gene id: 1123366:TH3_RS16040
uniprot id: A0A0B4Y1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1123366:TH3 RS09735
gene id: 1123366:TH3_RS09735
uniprot id: A0A0B4XYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1123366:TH3 RS16365
gene id: 1123366:TH3_RS16365
uniprot id: A0A0B4Y278
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123366:TH3 RS07000
gene id: 1123366:TH3_RS07000
uniprot id: A0A0B4XXC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1123366:TH3 RS00240
gene id: 1123366:TH3_RS00240
uniprot id: A0A0B4XU01
names: Similarity
messages: Belongs to the universal stress protein A family.

1123366:TH3 RS00280
gene id: 1123366:TH3_RS00280
uniprot id: A0A0B4XUK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS10820
gene id: 1123366:TH3_RS10820
uniprot id: A0A0B4Y0P8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.

1123366:TH3 RS06770
gene id: 1123366:TH3_RS06770
uniprot id: A0A0B4XYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1123366:TH3 RS10170
gene id: 1123366:TH3_RS10170
uniprot id: A0A0B4XZ38
names: Similarity
messages: Belongs to the HIBADH-related family.

1123366:TH3 RS06145
gene id: 1123366:TH3_RS06145
uniprot id: A0A0B4XY35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1123366:TH3 RS10720
gene id: 1123366:TH3_RS10720
uniprot id: A0A0B4Y0Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123366:TH3 RS10410
gene id: 1123366:TH3_RS10410
uniprot id: A0A0B4XV99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1123366:TH3 RS01885
gene id: 1123366:TH3_RS01885
uniprot id: A0A0B4XW48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1123366:TH3 RS18935
gene id: 1123366:TH3_RS18935
uniprot id: A0A0B4Y5B9
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS06210
gene id: 1123366:TH3_RS06210
uniprot id: A0A0B4XVW2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1123366:TH3 RS19090
gene id: 1123366:TH3_RS19090
uniprot id: A0A0B4Y5F8
names: Similarity
messages: Belongs to the pirin family.

1123366:TH3 RS02980
gene id: 1123366:TH3_RS02980
uniprot id: A0A0B4XVA7
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1123366:TH3 RS01040
gene id: 1123366:TH3_RS01040
uniprot id: A0A0B4XVP4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS04315
gene id: 1123366:TH3_RS04315
uniprot id: A0A0B4XUR6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1123366:TH3 RS08950
gene id: 1123366:TH3_RS08950
uniprot id: A0A0B4XZR4
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS01500
gene id: 1123366:TH3_RS01500
uniprot id: A0A0B4XVC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1123366:TH3 RS19560
gene id: 1123366:TH3_RS19560
uniprot id: A0A0B4Y5N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS05250
gene id: 1123366:TH3_RS05250
uniprot id: A0A0B4XVB0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS02920
gene id: 1123366:TH3_RS02920
uniprot id: A0A0B4XWJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1123366:TH3 RS01675
gene id: 1123366:TH3_RS01675
uniprot id: A0A0B4XVJ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS03295
gene id: 1123366:TH3_RS03295
uniprot id: A0A0B4XWF3
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS07695
gene id: 1123366:TH3_RS07695
uniprot id: A0A0B4XXP7
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1123366:TH3 RS10305
gene id: 1123366:TH3_RS10305
uniprot id: A0A0B4Y0E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1123366:TH3 RS01505
gene id: 1123366:TH3_RS01505
uniprot id: A0A0B4XQ08
names: Similarity
messages: Belongs to the PhoH family.

1123366:TH3 RS21595
gene id: 1123366:TH3_RS21595
uniprot id: A0A0B4Y6Q5
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1123366:TH3 RS02925
gene id: 1123366:TH3_RS02925
uniprot id: A0A0B4XW60
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1123366:TH3 RS16140
gene id: 1123366:TH3_RS16140
uniprot id: A0A0B4Y1D2
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS13175
gene id: 1123366:TH3_RS13175
uniprot id: A0A0B4Y0M6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1123366:TH3 RS18650
gene id: 1123366:TH3_RS18650
uniprot id: A0A0B4Y3G6
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1123366:TH3 RS21860
gene id: 1123366:TH3_RS21860
uniprot id: A0A0B4Y779
names: Similarity
messages: Belongs to the GSP E family.

1123366:TH3 RS20580
gene id: 1123366:TH3_RS20580
uniprot id: A0A0B4Y685
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS20945
gene id: 1123366:TH3_RS20945
uniprot id: A0A0B4Y486
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1123366:TH3 RS07290
gene id: 1123366:TH3_RS07290
uniprot id: A0A0B4XTF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS00260
gene id: 1123366:TH3_RS00260
uniprot id: A0A0B4XP76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1123366:TH3 RS13890
gene id: 1123366:TH3_RS13890
uniprot id: A0A0B4Y2L6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1123366:TH3 RS07340
gene id: 1123366:TH3_RS07340
uniprot id: A0A0B4XTG9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1123366:TH3 RS10265
gene id: 1123366:TH3_RS10265
uniprot id: A0A0B4XZ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS18530
gene id: 1123366:TH3_RS18530
uniprot id: A0A0B4Y3E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1123366:TH3 RS10255
gene id: 1123366:TH3_RS10255
uniprot id: A0A0B4Y0D4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS18475
gene id: 1123366:TH3_RS18475
uniprot id: A0A0B4XZY6
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1123366:TH3 RS19295
gene id: 1123366:TH3_RS19295
uniprot id: A0A0B4Y3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1123366:TH3 RS16625
gene id: 1123366:TH3_RS16625
uniprot id: A0A0B4Y2B9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS16280
gene id: 1123366:TH3_RS16280
uniprot id: A0A0B4Y3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS13640
gene id: 1123366:TH3_RS13640
uniprot id: A0A0B4Y2D2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS00070
gene id: 1123366:TH3_RS00070
uniprot id: A0A0B4XTW7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1123366:TH3 RS21575
gene id: 1123366:TH3_RS21575
uniprot id: A0A0B4Y6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS03080
gene id: 1123366:TH3_RS03080
uniprot id: A0A0B4XVC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1123366:TH3 RS12130
gene id: 1123366:TH3_RS12130
uniprot id: A0A0B4Y1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1123366:TH3 RS17155
gene id: 1123366:TH3_RS17155
uniprot id: A0A0B4Y237
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1123366:TH3 RS10385
gene id: 1123366:TH3_RS10385
uniprot id: A0A0B4XV92
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1123366:TH3 RS01905
gene id: 1123366:TH3_RS01905
uniprot id: A0A0B4XTG3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS18700
gene id: 1123366:TH3_RS18700
uniprot id: A0A0B4Y3H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1123366:TH3 RS03930
gene id: 1123366:TH3_RS03930
uniprot id: A0A0B4XRC4
names: Similarity
messages: Belongs to the MotB family.

1123366:TH3 RS19400
gene id: 1123366:TH3_RS19400
uniprot id: A0A0B4Y5M0
names: Similarity
messages: Belongs to the YciI family.

1123366:TH3 RS19270
gene id: 1123366:TH3_RS19270
uniprot id: A0A0B4Y3A6
names: Similarity
messages: Belongs to the thioredoxin family.

1123366:TH3 RS14855
gene id: 1123366:TH3_RS14855
uniprot id: A0A0B4Y334
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1123366:TH3 RS08040
gene id: 1123366:TH3_RS08040
uniprot id: A0A0B4XXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1123366:TH3 RS11940
gene id: 1123366:TH3_RS11940
uniprot id: A0A0B4XWB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS10505
gene id: 1123366:TH3_RS10505
uniprot id: A0A0B4XVB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1123366:TH3 RS01165
gene id: 1123366:TH3_RS01165
uniprot id: A0A0B4XVR3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS12445
gene id: 1123366:TH3_RS12445
uniprot id: A0A0B4Y1Q4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1123366:TH3 RS18665
gene id: 1123366:TH3_RS18665
uniprot id: A0A0B4Y532
names: Subunit
messages: Homodimer.

1123366:TH3 RS13155
gene id: 1123366:TH3_RS13155
uniprot id: A0A0B4XZS9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1123366:TH3 RS19530
gene id: 1123366:TH3_RS19530
uniprot id: A0A0B4Y5R3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS14025
gene id: 1123366:TH3_RS14025
uniprot id: A0A0B4Y2L2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS00255
gene id: 1123366:TH3_RS00255
uniprot id: A0A0B4XUK5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1123366:TH3 RS03985
gene id: 1123366:TH3_RS03985
uniprot id: A0A0B4XRD6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1123366:TH3 RS15620
gene id: 1123366:TH3_RS15620
uniprot id: A0A0B4Y3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS06795
gene id: 1123366:TH3_RS06795
uniprot id: A0A0B4XYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS02500
gene id: 1123366:TH3_RS02500
uniprot id: A0A0B4XV23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS15905
gene id: 1123366:TH3_RS15905
uniprot id: A0A0B4Y3L1
names: Similarity
messages: Belongs to the oxoprolinase family.

1123366:TH3 RS17250
gene id: 1123366:TH3_RS17250
uniprot id: A0A0B4Y2S0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1123366:TH3 RS05550
gene id: 1123366:TH3_RS05550
uniprot id: A0A0B4XXP3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1123366:TH3 RS12010
gene id: 1123366:TH3_RS12010
uniprot id: A0A0B4Y1H2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1123366:TH3 RS01550
gene id: 1123366:TH3_RS01550
uniprot id: A0A0B4XVE3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS08740
gene id: 1123366:TH3_RS08740
uniprot id: A0A0B4XXG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1123366:TH3 RS09765
gene id: 1123366:TH3_RS09765
uniprot id: A0A0B4XXZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS15705
gene id: 1123366:TH3_RS15705
uniprot id: A0A0B4XYA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS14055
gene id: 1123366:TH3_RS14055
uniprot id: A0A0B4Y2L5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS08375
gene id: 1123366:TH3_RS08375
uniprot id: A0A0B4XU36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123366:TH3 RS16315
gene id: 1123366:TH3_RS16315
uniprot id: A0A0B4Y268
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1123366:TH3 RS19845
gene id: 1123366:TH3_RS19845
uniprot id: A0A0B4Y0U8
names: Similarity
messages: Belongs to the TPP enzyme family.

1123366:TH3 RS18435
gene id: 1123366:TH3_RS18435
uniprot id: A0A0B4Y2R0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1123366:TH3 RS23490
gene id: 1123366:TH3_RS23490
uniprot id: A0A0B4XZ73
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1123366:TH3 RS11075
gene id: 1123366:TH3_RS11075
uniprot id: A0A0B4XZK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS11965
gene id: 1123366:TH3_RS11965
uniprot id: A0A0B4XWB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1123366:TH3 RS13090
gene id: 1123366:TH3_RS13090
uniprot id: A0A0B4Y221
names: Similarity
messages: Belongs to the leucine-binding protein family.

1123366:TH3 RS16765
gene id: 1123366:TH3_RS16765
uniprot id: A0A0B4Y464
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

1123366:TH3 RS10670
gene id: 1123366:TH3_RS10670
uniprot id: A0A0B4Y0Z0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1123366:TH3 RS04920
gene id: 1123366:TH3_RS04920
uniprot id: A0A0B4XW59
names: Similarity
messages: Belongs to the RelE toxin family.

1123366:TH3 RS09910
gene id: 1123366:TH3_RS09910
uniprot id: A0A0B4XUY9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1123366:TH3 RS12430
gene id: 1123366:TH3_RS12430
uniprot id: A0A0B4Y089
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1123366:TH3 RS15865
gene id: 1123366:TH3_RS15865
uniprot id: A0A0B4Y1Z4
names: Similarity
messages: Belongs to the UPF0386 family.

1123366:TH3 RS04760
gene id: 1123366:TH3_RS04760
uniprot id: A0A0B4XRU0
names: Subcellular Location Annotation
messages: Virion

1123366:TH3 RS10340
gene id: 1123366:TH3_RS10340
uniprot id: A0A0B4XZ77
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1123366:TH3 RS02025
gene id: 1123366:TH3_RS02025
uniprot id: A0A0B4XTI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1123366:TH3 RS03435
gene id: 1123366:TH3_RS03435
uniprot id: A0A0B4XVH9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS02775
gene id: 1123366:TH3_RS02775
uniprot id: A0A0B4XW23
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1123366:TH3 RS18485
gene id: 1123366:TH3_RS18485
uniprot id: A0A0B4Y2S2
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS07055
gene id: 1123366:TH3_RS07055
uniprot id: A0A0B4XWJ3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS17790
gene id: 1123366:TH3_RS17790
uniprot id: A0A0B4Y4R6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1123366:TH3 RS05985
gene id: 1123366:TH3_RS05985
uniprot id: A0A0B4XWR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1123366:TH3 RS13960
gene id: 1123366:TH3_RS13960
uniprot id: A0A0B4Y156
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS05990
gene id: 1123366:TH3_RS05990
uniprot id: A0A0B4XVR4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1123366:TH3 RS12105
gene id: 1123366:TH3_RS12105
uniprot id: A0A0B4Y1P4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS17360
gene id: 1123366:TH3_RS17360
uniprot id: A0A0B4Y265
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1123366:TH3 RS16965
gene id: 1123366:TH3_RS16965
uniprot id: A0A0B4Y4D4
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS20240
gene id: 1123366:TH3_RS20240
uniprot id: A0A0B4Y3V5
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1123366:TH3 RS00165
gene id: 1123366:TH3_RS00165
uniprot id: A0A0B4XTY6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS03205
gene id: 1123366:TH3_RS03205
uniprot id: A0A0B4XVF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

1123366:TH3 RS11475
gene id: 1123366:TH3_RS11475
uniprot id: A0A0B4XZS0
names: Similarity
messages: Belongs to the aldose epimerase family.

1123366:TH3 RS05620
gene id: 1123366:TH3_RS05620
uniprot id: A0A0B4XVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1123366:TH3 RS18950
gene id: 1123366:TH3_RS18950
uniprot id: A0A0B4Y3N7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123366:TH3 RS18395
gene id: 1123366:TH3_RS18395
uniprot id: A0A0B4Y4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1123366:TH3 RS01755
gene id: 1123366:TH3_RS01755
uniprot id: A0A0B4XQ75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1123366:TH3 RS09660
gene id: 1123366:TH3_RS09660
uniprot id: A0A0B4XYV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1123366:TH3 RS09000
gene id: 1123366:TH3_RS09000
uniprot id: A0A0B4XZS1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS19980
gene id: 1123366:TH3_RS19980
uniprot id: A0A0B4Y4C1
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS07430
gene id: 1123366:TH3_RS07430
uniprot id: A0A0B4XWR2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS07455
gene id: 1123366:TH3_RS07455
uniprot id: A0A0B4XWR5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS20770
gene id: 1123366:TH3_RS20770
uniprot id: A0A0B4Y452
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1123366:TH3 RS21430
gene id: 1123366:TH3_RS21430
uniprot id: A0A0B4Y581
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1123366:TH3 RS06005
gene id: 1123366:TH3_RS06005
uniprot id: A0A0B4XSL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1123366:TH3 RS18520
gene id: 1123366:TH3_RS18520
uniprot id: A0A0B4Y500
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1123366:TH3 RS19585
gene id: 1123366:TH3_RS19585
uniprot id: A0A0B4Y5P2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123366:TH3 RS16010
gene id: 1123366:TH3_RS16010
uniprot id: A0A0B4Y213
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1123366:TH3 RS20555
gene id: 1123366:TH3_RS20555
uniprot id: A0A0B4Y680
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1123366:TH3 RS02205
gene id: 1123366:TH3_RS02205
uniprot id: A0A0B4XW83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1123366:TH3 RS14705
gene id: 1123366:TH3_RS14705
uniprot id: A0A0B4XXV2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS03395
gene id: 1123366:TH3_RS03395
uniprot id: A0A0B4XWH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1123366:TH3 RS18550
gene id: 1123366:TH3_RS18550
uniprot id: A0A0B4XZZ9
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS14290
gene id: 1123366:TH3_RS14290
uniprot id: A0A0B4Y1C9
names: Similarity
messages: Belongs to the TPP enzyme family.

1123366:TH3 RS20360
gene id: 1123366:TH3_RS20360
uniprot id: A0A0B4Y4K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1123366:TH3 RS01225
gene id: 1123366:TH3_RS01225
uniprot id: A0A0B4XPU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1123366:TH3 RS10550
gene id: 1123366:TH3_RS10550
uniprot id: A0A0B4Y0J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1123366:TH3 RS03965
gene id: 1123366:TH3_RS03965
uniprot id: A0A0B4XVS8
names: Similarity
messages: Belongs to the type III secretion exporter family.

1123366:TH3 RS18505
gene id: 1123366:TH3_RS18505
uniprot id: A0A0B4Y3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1123366:TH3 RS02430
gene id: 1123366:TH3_RS02430
uniprot id: A0A0B4XWA4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1123366:TH3 RS19350
gene id: 1123366:TH3_RS19350
uniprot id: A0A0B4Y5L3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123366:TH3 RS00135
gene id: 1123366:TH3_RS00135
uniprot id: A0A0B4XP57
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123366:TH3 RS22310
gene id: 1123366:TH3_RS22310
uniprot id: A0A0B4XYW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DinB family.
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1123366:TH3 RS10495
gene id: 1123366:TH3_RS10495
uniprot id: A0A0B4Y0V4
names: Similarity
messages: Belongs to the TrpC family.

1123366:TH3 RS02640
gene id: 1123366:TH3_RS02640
uniprot id: A0A0B4XVZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS02900
gene id: 1123366:TH3_RS02900
uniprot id: A0A0B4XWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1123366:TH3 RS07120
gene id: 1123366:TH3_RS07120
uniprot id: A0A0B4XTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1123366:TH3 RS11915
gene id: 1123366:TH3_RS11915
uniprot id: A0A0B4Y031
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1123366:TH3 RS01185
gene id: 1123366:TH3_RS01185
uniprot id: A0A0B4XT14
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS15735
gene id: 1123366:TH3_RS15735
uniprot id: A0A0B4Y1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1123366:TH3 RS12490
gene id: 1123366:TH3_RS12490
uniprot id: A0A0B4Y1V0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1123366:TH3 RS00205
gene id: 1123366:TH3_RS00205
uniprot id: A0A0B4XUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1123366:TH3 RS09725
gene id: 1123366:TH3_RS09725
uniprot id: A0A0B4Y034
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS01485
gene id: 1123366:TH3_RS01485
uniprot id: A0A0B4XUK8
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS05235
gene id: 1123366:TH3_RS05235
uniprot id: A0A0B4XXI3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1123366:TH3 RS18900
gene id: 1123366:TH3_RS18900
uniprot id: A0A0B4Y3L9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1123366:TH3 RS05910
gene id: 1123366:TH3_RS05910
uniprot id: A0A0B4XSJ9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS06615
gene id: 1123366:TH3_RS06615
uniprot id: A0A0B4XYM6
names: Similarity
messages: Belongs to the histone deacetylase family.

1123366:TH3 RS17800
gene id: 1123366:TH3_RS17800
uniprot id: A0A0B4XZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1123366:TH3 RS11705
gene id: 1123366:TH3_RS11705
uniprot id: A0A0B4XZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1123366:TH3 RS10325
gene id: 1123366:TH3_RS10325
uniprot id: A0A0B4Y0S5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1123366:TH3 RS13555
gene id: 1123366:TH3_RS13555
uniprot id: A0A0B4XZZ2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS06110
gene id: 1123366:TH3_RS06110
uniprot id: A0A0B4XVU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1123366:TH3 RS14875
gene id: 1123366:TH3_RS14875
uniprot id: A0A0B4Y378
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1123366:TH3 RS05975
gene id: 1123366:TH3_RS05975
uniprot id: A0A0B4XYA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1123366:TH3 RS19125
gene id: 1123366:TH3_RS19125
uniprot id: A0A0B4Y0C0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS06080
gene id: 1123366:TH3_RS06080
uniprot id: A0A0B4XWT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1123366:TH3 RS07630
gene id: 1123366:TH3_RS07630
uniprot id: A0A0B4XWU5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1123366:TH3 RS19085
gene id: 1123366:TH3_RS19085
uniprot id: A0A0B4Y364
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1123366:TH3 RS16085
gene id: 1123366:TH3_RS16085
uniprot id: A0A0B4Y229
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1123366:TH3 RS06635
gene id: 1123366:TH3_RS06635
uniprot id: A0A0B4XW87
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1123366:TH3 RS12155
gene id: 1123366:TH3_RS12155
uniprot id: A0A0B4Y1Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1123366:TH3 RS00480
gene id: 1123366:TH3_RS00480
uniprot id: A0A0B4XUN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1123366:TH3 RS07835
gene id: 1123366:TH3_RS07835
uniprot id: A0A0B4XWY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1123366:TH3 RS10760
gene id: 1123366:TH3_RS10760
uniprot id: A0A0B4Y103
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1123366:TH3 RS10220
gene id: 1123366:TH3_RS10220
uniprot id: A0A0B4XY77
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1123366:TH3 RS10155
gene id: 1123366:TH3_RS10155
uniprot id: A0A0B4Y0Q3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS09920
gene id: 1123366:TH3_RS09920
uniprot id: A0A0B4XY17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS20250
gene id: 1123366:TH3_RS20250
uniprot id: A0A0B4Y624
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1123366:TH3 RS19175
gene id: 1123366:TH3_RS19175
uniprot id: A0A0B4Y0D1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1123366:TH3 RS21005
gene id: 1123366:TH3_RS21005
uniprot id: A0A0B4Y6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1123366:TH3 RS15835
gene id: 1123366:TH3_RS15835
uniprot id: A0A0B4XYD0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS10640
gene id: 1123366:TH3_RS10640
uniprot id: A0A0B4XYF1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1123366:TH3 RS02275
gene id: 1123366:TH3_RS02275
uniprot id: A0A0B4XTN4
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS07005
gene id: 1123366:TH3_RS07005
uniprot id: A0A0B4XWI4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS08825
gene id: 1123366:TH3_RS08825
uniprot id: A0A0B4XZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS12665
gene id: 1123366:TH3_RS12665
uniprot id: A0A0B4XZI0
names: Similarity
messages: Belongs to the IlvD/Edd family.

1123366:TH3 RS08340
gene id: 1123366:TH3_RS08340
uniprot id: A0A0B4XU31
names: Similarity
messages: Belongs to the histone deacetylase family.

1123366:TH3 RS12995
gene id: 1123366:TH3_RS12995
uniprot id: A0A0B4XWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS15260
gene id: 1123366:TH3_RS15260
uniprot id: A0A0B4Y3A8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS06035
gene id: 1123366:TH3_RS06035
uniprot id: A0A0B4XVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1123366:TH3 RS09790
gene id: 1123366:TH3_RS09790
uniprot id: A0A0B4XXZ8
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1123366:TH3 RS01745
gene id: 1123366:TH3_RS01745
uniprot id: A0A0B4XW32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1123366:TH3 RS03150
gene id: 1123366:TH3_RS03150
uniprot id: A0A0B4XQY5
names: Similarity
messages: Belongs to the peptidase U62 family.

1123366:TH3 RS11115
gene id: 1123366:TH3_RS11115
uniprot id: A0A0B4Y0X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1123366:TH3 RS14085
gene id: 1123366:TH3_RS14085
uniprot id: A0A0B4XXG0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS06245
gene id: 1123366:TH3_RS06245
uniprot id: A0A0B4XY63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS06750
gene id: 1123366:TH3_RS06750
uniprot id: A0A0B4XT74
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS15535
gene id: 1123366:TH3_RS15535
uniprot id: A0A0B4Y3I0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS01595
gene id: 1123366:TH3_RS01595
uniprot id: A0A0B4XVZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1123366:TH3 RS13535
gene id: 1123366:TH3_RS13535
uniprot id: A0A0B4Y2E1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123366:TH3 RS05710
gene id: 1123366:TH3_RS05710
uniprot id: A0A0B4XSF2
names: PTM
messages: Binds 1 heme group per subunit.

1123366:TH3 RS12670
gene id: 1123366:TH3_RS12670
uniprot id: A0A0B4Y1Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

1123366:TH3 RS17240
gene id: 1123366:TH3_RS17240
uniprot id: A0A0B4Y4G1
names: Similarity
messages: Belongs to the Gfa family.

1123366:TH3 RS11400
gene id: 1123366:TH3_RS11400
uniprot id: A0A0B4XZQ2
names: Similarity
messages: Belongs to the pirin family.

1123366:TH3 RS11195
gene id: 1123366:TH3_RS11195
uniprot id: A0A0B4XVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS10690
gene id: 1123366:TH3_RS10690
uniprot id: A0A0B4XYF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1123366:TH3 RS16285
gene id: 1123366:TH3_RS16285
uniprot id: A0A0B4XYL8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1123366:TH3 RS10565
gene id: 1123366:TH3_RS10565
uniprot id: A0A0B4XYE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1123366:TH3 RS01795
gene id: 1123366:TH3_RS01795
uniprot id: A0A0B4XVK6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1123366:TH3 RS16700
gene id: 1123366:TH3_RS16700
uniprot id: A0A0B4Y2D3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1123366:TH3 RS06410
gene id: 1123366:TH3_RS06410
uniprot id: A0A0B4XWZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS18500
gene id: 1123366:TH3_RS18500
uniprot id: A0A0B4XZY9
names: Similarity
messages: Belongs to the AHA1 family.

1123366:TH3 RS12140
gene id: 1123366:TH3_RS12140
uniprot id: A0A0B4XWE2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1123366:TH3 RS14465
gene id: 1123366:TH3_RS14465
uniprot id: A0A0B4Y0J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1123366:TH3 RS15015
gene id: 1123366:TH3_RS15015
uniprot id: A0A0B4Y1M9
names: Similarity
messages: Belongs to the aspartokinase family.

1123366:TH3 RS20925
gene id: 1123366:TH3_RS20925
uniprot id: A0A0B4Y6K0
names: Similarity
messages: Belongs to the CobH/CbiC family.

1123366:TH3 RS05180
gene id: 1123366:TH3_RS05180
uniprot id: A0A0B4XXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS18215
gene id: 1123366:TH3_RS18215
uniprot id: A0A0B4Y4U7
names: Similarity
messages: Belongs to the glutamate synthase family.

1123366:TH3 RS17935
gene id: 1123366:TH3_RS17935
uniprot id: A0A0B4Y2F8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1123366:TH3 RS08665
gene id: 1123366:TH3_RS08665
uniprot id: A0A0B4XXE4
names: Similarity
messages: Belongs to the group II decarboxylase family.

1123366:TH3 RS03805
gene id: 1123366:TH3_RS03805
uniprot id: A0A0B4XR99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1123366:TH3 RS02650
gene id: 1123366:TH3_RS02650
uniprot id: A0A0B4XV49
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS13655
gene id: 1123366:TH3_RS13655
uniprot id: A0A0B4Y011
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1123366:TH3 RS10910
gene id: 1123366:TH3_RS10910
uniprot id: A0A0B4Y125
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS03705
gene id: 1123366:TH3_RS03705
uniprot id: A0A0B4XR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS11645
gene id: 1123366:TH3_RS11645
uniprot id: A0A0B4Y195
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS10540
gene id: 1123366:TH3_RS10540
uniprot id: A0A0B4XYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1123366:TH3 RS06070
gene id: 1123366:TH3_RS06070
uniprot id: A0A0B4XY18
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1123366:TH3 RS20875
gene id: 1123366:TH3_RS20875
uniprot id: A0A0B4Y6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1123366:TH3 RS06020
gene id: 1123366:TH3_RS06020
uniprot id: A0A0B4XY04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1123366:TH3 RS09615
gene id: 1123366:TH3_RS09615
uniprot id: A0A0B4XXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1123366:TH3 RS12900
gene id: 1123366:TH3_RS12900
uniprot id: A0A0B4XZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS06555
gene id: 1123366:TH3_RS06555
uniprot id: A0A0B4XX12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1123366:TH3 RS01735
gene id: 1123366:TH3_RS01735
uniprot id: A0A0B4XUR5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1123366:TH3 RS12025
gene id: 1123366:TH3_RS12025
uniprot id: A0A0B4XZ60
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1123366:TH3 RS06085
gene id: 1123366:TH3_RS06085
uniprot id: A0A0B4XVT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1123366:TH3 RS01375
gene id: 1123366:TH3_RS01375
uniprot id: A0A0B4XVA5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1123366:TH3 RS10355
gene id: 1123366:TH3_RS10355
uniprot id: A0A0B4Y0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1123366:TH3 RS11695
gene id: 1123366:TH3_RS11695
uniprot id: A0A0B4XW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1123366:TH3 RS00295
gene id: 1123366:TH3_RS00295
uniprot id: A0A0B4XSK5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1123366:TH3 RS08955
gene id: 1123366:TH3_RS08955
uniprot id: A0A0B4XUE1
names: Similarity
messages: Belongs to the ArsC family.

1123366:TH3 RS08910
gene id: 1123366:TH3_RS08910
uniprot id: A0A0B4XYG0
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS05295
gene id: 1123366:TH3_RS05295
uniprot id: A0A0B4XWD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1123366:TH3 RS14890
gene id: 1123366:TH3_RS14890
uniprot id: A0A0B4Y1L4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1123366:TH3 RS15250
gene id: 1123366:TH3_RS15250
uniprot id: A0A0B4Y0W7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1123366:TH3 RS10135
gene id: 1123366:TH3_RS10135
uniprot id: A0A0B4Y0B1
names: Similarity
messages: Belongs to the leucine-binding protein family.

1123366:TH3 RS03245
gene id: 1123366:TH3_RS03245
uniprot id: A0A0B4XWD9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1123366:TH3 RS15730
gene id: 1123366:TH3_RS15730
uniprot id: A0A0B4XYB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1123366:TH3 RS17815
gene id: 1123366:TH3_RS17815
uniprot id: A0A0B4Y4S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1123366:TH3 RS10490
gene id: 1123366:TH3_RS10490
uniprot id: A0A0B4XYD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS15575
gene id: 1123366:TH3_RS15575
uniprot id: A0A0B4Y1V3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123366:TH3 RS16795
gene id: 1123366:TH3_RS16795
uniprot id: A0A0B4XYW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1123366:TH3 RS06595
gene id: 1123366:TH3_RS06595
uniprot id: A0A0B4XYE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS18780
gene id: 1123366:TH3_RS18780
uniprot id: A0A0B4Y2Y2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123366:TH3 RS09140
gene id: 1123366:TH3_RS09140
uniprot id: A0A0B4XXN5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS01045
gene id: 1123366:TH3_RS01045
uniprot id: A0A0B4XV33
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS14155
gene id: 1123366:TH3_RS14155
uniprot id: A0A0B4Y2N6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS17945
gene id: 1123366:TH3_RS17945
uniprot id: A0A0B4Y4Q0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1123366:TH3 RS21570
gene id: 1123366:TH3_RS21570
uniprot id: A0A0B4Y714
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS09500
gene id: 1123366:TH3_RS09500
uniprot id: A0A0B4XZZ3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1123366:TH3 RS08670
gene id: 1123366:TH3_RS08670
uniprot id: A0A0B4XZV9
names: Similarity
messages: Belongs to the PhzF family.

1123366:TH3 RS19650
gene id: 1123366:TH3_RS19650
uniprot id: A0A0B4Y3K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS09170
gene id: 1123366:TH3_RS09170
uniprot id: A0A0B4XXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS20960
gene id: 1123366:TH3_RS20960
uniprot id: A0A0B4Y1D8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1123366:TH3 RS12455
gene id: 1123366:TH3_RS12455
uniprot id: A0A0B4Y093
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1123366:TH3 RS12875
gene id: 1123366:TH3_RS12875
uniprot id: A0A0B4XZM0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123366:TH3 RS19440
gene id: 1123366:TH3_RS19440
uniprot id: A0A0B4Y407
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1123366:TH3 RS08395
gene id: 1123366:TH3_RS08395
uniprot id: A0A0B4XZD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS09945
gene id: 1123366:TH3_RS09945
uniprot id: A0A0B4XY21
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1123366:TH3 RS17080
gene id: 1123366:TH3_RS17080
uniprot id: A0A0B4Y227
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

1123366:TH3 RS03680
gene id: 1123366:TH3_RS03680
uniprot id: A0A0B4XR79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

1123366:TH3 RS18785
gene id: 1123366:TH3_RS18785
uniprot id: A0A0B4Y586
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1123366:TH3 RS17060
gene id: 1123366:TH3_RS17060
uniprot id: A0A0B4Y4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1123366:TH3 RS05780
gene id: 1123366:TH3_RS05780
uniprot id: A0A0B4XXU5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1123366:TH3 RS05205
gene id: 1123366:TH3_RS05205
uniprot id: A0A0B4XXV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123366:TH3 RS20645
gene id: 1123366:TH3_RS20645
uniprot id: A0A0B4Y429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS05630
gene id: 1123366:TH3_RS05630
uniprot id: A0A0B4XXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS17720
gene id: 1123366:TH3_RS17720
uniprot id: A0A0B4Y4L9
names: Similarity
messages: Belongs to the threonine synthase family.

1123366:TH3 RS17920
gene id: 1123366:TH3_RS17920
uniprot id: A0A0B4Y4P5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1123366:TH3 RS20065
gene id: 1123366:TH3_RS20065
uniprot id: A0A0B4Y3S1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-67 and Arg-70) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1123366:TH3 RS18400
gene id: 1123366:TH3_RS18400
uniprot id: A0A0B4XZX0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS05185
gene id: 1123366:TH3_RS05185
uniprot id: A0A0B4XXH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS06090
gene id: 1123366:TH3_RS06090
uniprot id: A0A0B4XYC1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1123366:TH3 RS10185
gene id: 1123366:TH3_RS10185
uniprot id: A0A0B4Y0B9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1123366:TH3 RS06075
gene id: 1123366:TH3_RS06075
uniprot id: A0A0B4XSN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1123366:TH3 RS18065
gene id: 1123366:TH3_RS18065
uniprot id: A0A0B4Y4R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1123366:TH3 RS06125
gene id: 1123366:TH3_RS06125
uniprot id: A0A0B4XSP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1123366:TH3 RS13245
gene id: 1123366:TH3_RS13245
uniprot id: A0A0B4XWY8
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1123366:TH3 RS09900
gene id: 1123366:TH3_RS09900
uniprot id: A0A0B4Y0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1123366:TH3 RS10765
gene id: 1123366:TH3_RS10765
uniprot id: A0A0B4Y0N5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1123366:TH3 RS10430
gene id: 1123366:TH3_RS10430
uniprot id: A0A0B4Y0H0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1123366:TH3 RS14515
gene id: 1123366:TH3_RS14515
uniprot id: A0A0B4Y0K3
names: Similarity
messages: Belongs to the virb1 family.

1123366:TH3 RS17765
gene id: 1123366:TH3_RS17765
uniprot id: A0A0B4Y4R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1123366:TH3 RS19890
gene id: 1123366:TH3_RS19890
uniprot id: A0A0B4Y5Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1123366:TH3 RS20950
gene id: 1123366:TH3_RS20950
uniprot id: A0A0B4Y6K8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1123366:TH3 RS14485
gene id: 1123366:TH3_RS14485
uniprot id: A0A0B4Y1H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS05300
gene id: 1123366:TH3_RS05300
uniprot id: A0A0B4XVB8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1123366:TH3 RS19260
gene id: 1123366:TH3_RS19260
uniprot id: A0A0B4Y0F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1123366:TH3 RS06925
gene id: 1123366:TH3_RS06925
uniprot id: A0A0B4XTA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS19040
gene id: 1123366:TH3_RS19040
uniprot id: A0A0B4Y5E4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS09880
gene id: 1123366:TH3_RS09880
uniprot id: A0A0B4XUY2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS17100
gene id: 1123366:TH3_RS17100
uniprot id: A0A0B4Y2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS10195
gene id: 1123366:TH3_RS10195
uniprot id: A0A0B4XZ43
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS13205
gene id: 1123366:TH3_RS13205
uniprot id: A0A0B4XZT9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS21580
gene id: 1123366:TH3_RS21580
uniprot id: A0A0B4Y1V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS21170
gene id: 1123366:TH3_RS21170
uniprot id: A0A0B4Y517
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1123366:TH3 RS23320
gene id: 1123366:TH3_RS23320
uniprot id: A0A0B4XZI6
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

1123366:TH3 RS02010
gene id: 1123366:TH3_RS02010
uniprot id: A0A0B4XW64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1123366:TH3 RS10090
gene id: 1123366:TH3_RS10090
uniprot id: A0A0B4XV28
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1123366:TH3 RS10335
gene id: 1123366:TH3_RS10335
uniprot id: A0A0B4XV82
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1123366:TH3 RS00400
gene id: 1123366:TH3_RS00400
uniprot id: A0A0B4XVC0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123366:TH3 RS05305
gene id: 1123366:TH3_RS05305
uniprot id: A0A0B4XXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS09225
gene id: 1123366:TH3_RS09225
uniprot id: A0A0B4XXQ9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1123366:TH3 RS01490
gene id: 1123366:TH3_RS01490
uniprot id: A0A0B4XT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS19305
gene id: 1123366:TH3_RS19305
uniprot id: A0A0B4Y5F7
names: Similarity
messages: Belongs to the Gfa family.

1123366:TH3 RS01605
gene id: 1123366:TH3_RS01605
uniprot id: A0A0B4XQ41
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS04105
gene id: 1123366:TH3_RS04105
uniprot id: A0A0B4XX13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1123366:TH3 RS09080
gene id: 1123366:TH3_RS09080
uniprot id: A0A0B4XUH0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS15450
gene id: 1123366:TH3_RS15450
uniprot id: A0A0B4Y3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1123366:TH3 RS18085
gene id: 1123366:TH3_RS18085
uniprot id: A0A0B4Y4W4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123366:TH3 RS04460
gene id: 1123366:TH3_RS04460
uniprot id: A0A0B4XW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1123366:TH3 RS21125
gene id: 1123366:TH3_RS21125
uniprot id: A0A0B4Y6Q2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS08260
gene id: 1123366:TH3_RS08260
uniprot id: A0A0B4XZM1
names: Subcellular Location Annotation
messages: target cell cytoplasm

1123366:TH3 RS15570
gene id: 1123366:TH3_RS15570
uniprot id: A0A0B4XY86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123366:TH3 RS05870
gene id: 1123366:TH3_RS05870
uniprot id: A0A0B4XVP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS20570
gene id: 1123366:TH3_RS20570
uniprot id: A0A0B4Y417
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1123366:TH3 RS07195
gene id: 1123366:TH3_RS07195
uniprot id: A0A0B4XTE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1123366:TH3 RS13400
gene id: 1123366:TH3_RS13400
uniprot id: A0A0B4XZX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1123366:TH3 RS07070
gene id: 1123366:TH3_RS07070
uniprot id: A0A0B4XTC0
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1123366:TH3 RS05865
gene id: 1123366:TH3_RS05865
uniprot id: A0A0B4XWP1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123366:TH3 RS04275
gene id: 1123366:TH3_RS04275
uniprot id: A0A0B4XX46
names: Similarity
messages: Belongs to the LOG family.

1123366:TH3 RS05700
gene id: 1123366:TH3_RS05700
uniprot id: A0A0B4XY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS20280
gene id: 1123366:TH3_RS20280
uniprot id: A0A0B4Y112
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1123366:TH3 RS07780
gene id: 1123366:TH3_RS07780
uniprot id: A0A0B4XXR4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

1123366:TH3 RS15375
gene id: 1123366:TH3_RS15375
uniprot id: A0A0B4Y0Z7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1123366:TH3 RS17145
gene id: 1123366:TH3_RS17145
uniprot id: A0A0B4XZ71
names: Similarity
messages: Belongs to the peptidase M16 family.

1123366:TH3 RS17510
gene id: 1123366:TH3_RS17510
uniprot id: A0A0B4Y285
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1123366:TH3 RS20915
gene id: 1123366:TH3_RS20915
uniprot id: A0A0B4Y4W5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1123366:TH3 RS01565
gene id: 1123366:TH3_RS01565
uniprot id: A0A0B4XT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1123366:TH3 RS19975
gene id: 1123366:TH3_RS19975
uniprot id: A0A0B4Y0W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1123366:TH3 RS02705
gene id: 1123366:TH3_RS02705
uniprot id: A0A0B4XTU9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1123366:TH3 RS09070
gene id: 1123366:TH3_RS09070
uniprot id: A0A0B4Y055
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS12260
gene id: 1123366:TH3_RS12260
uniprot id: A0A0B4Y1L1
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1123366:TH3 RS12950
gene id: 1123366:TH3_RS12950
uniprot id: A0A0B4Y0I1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS10360
gene id: 1123366:TH3_RS10360
uniprot id: A0A0B4XV87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1123366:TH3 RS18800
gene id: 1123366:TH3_RS18800
uniprot id: A0A0B4Y3J9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1123366:TH3 RS16030
gene id: 1123366:TH3_RS16030
uniprot id: A0A0B4XYH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS00020
gene id: 1123366:TH3_RS00020
uniprot id: A0A0B4XTV7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1123366:TH3 RS19520
gene id: 1123366:TH3_RS19520
uniprot id: A0A0B4Y449
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS19780
gene id: 1123366:TH3_RS19780
uniprot id: A0A0B4Y3M0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS12165
gene id: 1123366:TH3_RS12165
uniprot id: A0A0B4XWE5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1123366:TH3 RS18405
gene id: 1123366:TH3_RS18405
uniprot id: A0A0B4Y3C3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1123366:TH3 RS02555
gene id: 1123366:TH3_RS02555
uniprot id: A0A0B4XTR7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123366:TH3 RS00440
gene id: 1123366:TH3_RS00440
uniprot id: A0A0B4XU44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS16180
gene id: 1123366:TH3_RS16180
uniprot id: A0A0B4XYJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1123366:TH3 RS09870
gene id: 1123366:TH3_RS09870
uniprot id: A0A0B4Y0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS14715
gene id: 1123366:TH3_RS14715
uniprot id: A0A0B4Y0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS17420
gene id: 1123366:TH3_RS17420
uniprot id: A0A0B4Y4H9
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS09940
gene id: 1123366:TH3_RS09940
uniprot id: A0A0B4XZ02
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1123366:TH3 RS08245
gene id: 1123366:TH3_RS08245
uniprot id: A0A0B4XZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS19330
gene id: 1123366:TH3_RS19330
uniprot id: A0A0B4Y5G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1123366:TH3 RS10415
gene id: 1123366:TH3_RS10415
uniprot id: A0A0B4XZ94
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1123366:TH3 RS01635
gene id: 1123366:TH3_RS01635
uniprot id: A0A0B4XUQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS11350
gene id: 1123366:TH3_RS11350
uniprot id: A0A0B4XZP4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS15745
gene id: 1123366:TH3_RS15745
uniprot id: A0A0B4Y3L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1123366:TH3 RS03870
gene id: 1123366:TH3_RS03870
uniprot id: A0A0B4XX36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1123366:TH3 RS20710
gene id: 1123366:TH3_RS20710
uniprot id: A0A0B4Y194
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS16095
gene id: 1123366:TH3_RS16095
uniprot id: A0A0B4Y3T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1123366:TH3 RS01330
gene id: 1123366:TH3_RS01330
uniprot id: A0A0B4XPW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1123366:TH3 RS03425
gene id: 1123366:TH3_RS03425
uniprot id: A0A0B4XWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS14170
gene id: 1123366:TH3_RS14170
uniprot id: A0A0B4Y0B7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1123366:TH3 RS18765
gene id: 1123366:TH3_RS18765
uniprot id: A0A0B4Y557
names: Similarity
messages: Belongs to the PspA/IM30 family.

1123366:TH3 RS01255
gene id: 1123366:TH3_RS01255
uniprot id: A0A0B4XUH5
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1123366:TH3 RS05815
gene id: 1123366:TH3_RS05815
uniprot id: A0A0B4XWN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS13365
gene id: 1123366:TH3_RS13365
uniprot id: A0A0B4Y283
names: Similarity
messages: Belongs to the GSP E family.

1123366:TH3 RS11675
gene id: 1123366:TH3_RS11675
uniprot id: A0A0B4XZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS09400
gene id: 1123366:TH3_RS09400
uniprot id: A0A0B4XXS6
names: Similarity
messages: Belongs to the UPF0246 family.

1123366:TH3 RS01310
gene id: 1123366:TH3_RS01310
uniprot id: A0A0B4XUI2
names: Similarity
messages: Belongs to the RelE toxin family.

1123366:TH3 RS13500
gene id: 1123366:TH3_RS13500
uniprot id: A0A0B4Y0V0
names: Similarity
messages: Belongs to the DapA family.

1123366:TH3 RS20670
gene id: 1123366:TH3_RS20670
uniprot id: A0A0B4Y431
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1123366:TH3 RS07945
gene id: 1123366:TH3_RS07945
uniprot id: A0A0B4XX01
names: Similarity
messages: Belongs to the peptidase C56 family.

1123366:TH3 RS05115
gene id: 1123366:TH3_RS05115
uniprot id: A0A0B4XS10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS04050
gene id: 1123366:TH3_RS04050
uniprot id: A0A0B4XX65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1123366:TH3 RS06230
gene id: 1123366:TH3_RS06230
uniprot id: A0A0B4XWW7
names: Similarity
messages: Belongs to the AHA1 family.

1123366:TH3 RS10665
gene id: 1123366:TH3_RS10665
uniprot id: A0A0B4XYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1123366:TH3 RS06920
gene id: 1123366:TH3_RS06920
uniprot id: A0A0B4XYM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS12850
gene id: 1123366:TH3_RS12850
uniprot id: A0A0B4XZL4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1123366:TH3 RS01890
gene id: 1123366:TH3_RS01890
uniprot id: A0A0B4XVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1123366:TH3 RS12945
gene id: 1123366:TH3_RS12945
uniprot id: A0A0B4XWT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1123366:TH3 RS06330
gene id: 1123366:TH3_RS06330
uniprot id: A0A0B4XWY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1123366:TH3 RS10315
gene id: 1123366:TH3_RS10315
uniprot id: A0A0B4XZ72
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1123366:TH3 RS06530
gene id: 1123366:TH3_RS06530
uniprot id: A0A0B4XX08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1123366:TH3 RS13000
gene id: 1123366:TH3_RS13000
uniprot id: A0A0B4Y0J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS07615
gene id: 1123366:TH3_RS07615
uniprot id: A0A0B4XYZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS09755
gene id: 1123366:TH3_RS09755
uniprot id: A0A0B4XUV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS10520
gene id: 1123366:TH3_RS10520
uniprot id: A0A0B4Y0V9
names: Similarity
messages: Belongs to the citrate synthase family.

1123366:TH3 RS01785
gene id: 1123366:TH3_RS01785
uniprot id: A0A0B4XUS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

1123366:TH3 RS00655
gene id: 1123366:TH3_RS00655
uniprot id: A0A0B4XVG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS13590
gene id: 1123366:TH3_RS13590
uniprot id: A0A0B4Y2B8
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS04245
gene id: 1123366:TH3_RS04245
uniprot id: A0A0B4XXD5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS10370
gene id: 1123366:TH3_RS10370
uniprot id: A0A0B4XYA8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1123366:TH3 RS00455
gene id: 1123366:TH3_RS00455
uniprot id: A0A0B4XUN1
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1123366:TH3 RS06645
gene id: 1123366:TH3_RS06645
uniprot id: A0A0B4XYI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1123366:TH3 RS09975
gene id: 1123366:TH3_RS09975
uniprot id: A0A0B4Y0M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1123366:TH3 RS17570
gene id: 1123366:TH3_RS17570
uniprot id: A0A0B4Y4J8
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

1123366:TH3 RS18820
gene id: 1123366:TH3_RS18820
uniprot id: A0A0B4Y056
names: Similarity
messages: Belongs to the DEAD box helicase family.

1123366:TH3 RS07625
gene id: 1123366:TH3_RS07625
uniprot id: A0A0B4XXN8
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1123366:TH3 RS10850
gene id: 1123366:TH3_RS10850
uniprot id: A0A0B4XZH1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS20795
gene id: 1123366:TH3_RS20795
uniprot id: A0A0B4Y458
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1123366:TH3 RS18610
gene id: 1123366:TH3_RS18610
uniprot id: A0A0B4Y546
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS06440
gene id: 1123366:TH3_RS06440
uniprot id: A0A0B4XW24
names: Similarity
messages: Belongs to the AHA1 family.

1123366:TH3 RS10450
gene id: 1123366:TH3_RS10450
uniprot id: A0A0B4Y0U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1123366:TH3 RS05770
gene id: 1123366:TH3_RS05770
uniprot id: A0A0B4XVL8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS15805
gene id: 1123366:TH3_RS15805
uniprot id: A0A0B4Y3J4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS01305
gene id: 1123366:TH3_RS01305
uniprot id: A0A0B4XPW0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1123366:TH3 RS20520
gene id: 1123366:TH3_RS20520
uniprot id: A0A0B4Y411
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1123366:TH3 RS11885
gene id: 1123366:TH3_RS11885
uniprot id: A0A0B4XWA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS02690
gene id: 1123366:TH3_RS02690
uniprot id: A0A0B4XW04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1123366:TH3 RS10405
gene id: 1123366:TH3_RS10405
uniprot id: A0A0B4Y0G4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1123366:TH3 RS05195
gene id: 1123366:TH3_RS05195
uniprot id: A0A0B4XWB3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS03005
gene id: 1123366:TH3_RS03005
uniprot id: A0A0B4XVB1
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS09700
gene id: 1123366:TH3_RS09700
uniprot id: A0A0B4Y028
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1123366:TH3 RS01705
gene id: 1123366:TH3_RS01705
uniprot id: A0A0B4XQ67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS13370
gene id: 1123366:TH3_RS13370
uniprot id: A0A0B4XX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1123366:TH3 RS14830
gene id: 1123366:TH3_RS14830
uniprot id: A0A0B4Y329
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS05110
gene id: 1123366:TH3_RS05110
uniprot id: A0A0B4XXF7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1123366:TH3 RS12605
gene id: 1123366:TH3_RS12605
uniprot id: A0A0B4Y0B8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1123366:TH3 RS09690
gene id: 1123366:TH3_RS09690
uniprot id: A0A0B4XXX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1123366:TH3 RS15390
gene id: 1123366:TH3_RS15390
uniprot id: A0A0B4XY65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1123366:TH3 RS07500
gene id: 1123366:TH3_RS07500
uniprot id: A0A0B4XXL8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1123366:TH3 RS07325
gene id: 1123366:TH3_RS07325
uniprot id: A0A0B4XWP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS14425
gene id: 1123366:TH3_RS14425
uniprot id: A0A0B4Y312
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1123366:TH3 RS01895
gene id: 1123366:TH3_RS01895
uniprot id: A0A0B4XQA1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1123366:TH3 RS05790
gene id: 1123366:TH3_RS05790
uniprot id: A0A0B4XWM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1123366:TH3 RS18015
gene id: 1123366:TH3_RS18015
uniprot id: A0A0B4Y4Q9
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1123366:TH3 RS21590
gene id: 1123366:TH3_RS21590
uniprot id: A0A0B4Y4Q6
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1123366:TH3 RS17585
gene id: 1123366:TH3_RS17585
uniprot id: A0A0B4Y296
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123366:TH3 RS01465
gene id: 1123366:TH3_RS01465
uniprot id: A0A0B4XT64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1123366:TH3 RS07185
gene id: 1123366:TH3_RS07185
uniprot id: A0A0B4XZ07
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1123366:TH3 RS01160
gene id: 1123366:TH3_RS01160
uniprot id: A0A0B4XT09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS18460
gene id: 1123366:TH3_RS18460
uniprot id: A0A0B4Y2R5
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1123366:TH3 RS09415
gene id: 1123366:TH3_RS09415
uniprot id: A0A0B4XUN7
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS10680
gene id: 1123366:TH3_RS10680
uniprot id: A0A0B4XVE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123366:TH3 RS02945
gene id: 1123366:TH3_RS02945
uniprot id: A0A0B4XWK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1123366:TH3 RS17495
gene id: 1123366:TH3_RS17495
uniprot id: A0A0B4Y4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1123366:TH3 RS21185
gene id: 1123366:TH3_RS21185
uniprot id: A0A0B4Y6J1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1123366:TH3 RS14520
gene id: 1123366:TH3_RS14520
uniprot id: A0A0B4Y325
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Belongs to the peptidase S26C family.
messages: Periplasm

1123366:TH3 RS08095
gene id: 1123366:TH3_RS08095
uniprot id: A0A0B4XX26
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1123366:TH3 RS04240
gene id: 1123366:TH3_RS04240
uniprot id: A0A0B4XUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS17750
gene id: 1123366:TH3_RS17750
uniprot id: A0A0B4XZI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1123366:TH3 RS12495
gene id: 1123366:TH3_RS12495
uniprot id: A0A0B4Y1R5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1123366:TH3 RS14915
gene id: 1123366:TH3_RS14915
uniprot id: A0A0B4Y1L6
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1123366:TH3 RS01625
gene id: 1123366:TH3_RS01625
uniprot id: A0A0B4XVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS05635
gene id: 1123366:TH3_RS05635
uniprot id: A0A0B4XSD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS05680
gene id: 1123366:TH3_RS05680
uniprot id: A0A0B4XXR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1123366:TH3 RS03455
gene id: 1123366:TH3_RS03455
uniprot id: A0A0B4XR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS18030
gene id: 1123366:TH3_RS18030
uniprot id: A0A0B4Y2H6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1123366:TH3 RS15055
gene id: 1123366:TH3_RS15055
uniprot id: A0A0B4Y372
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS15195
gene id: 1123366:TH3_RS15195
uniprot id: A0A0B4Y1Q2
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS13720
gene id: 1123366:TH3_RS13720
uniprot id: A0A0B4XX74
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS09780
gene id: 1123366:TH3_RS09780
uniprot id: A0A0B4XUW0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS13355
gene id: 1123366:TH3_RS13355
uniprot id: A0A0B4XZW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1123366:TH3 RS08500
gene id: 1123366:TH3_RS08500
uniprot id: A0A0B4XU59
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1123366:TH3 RS09830
gene id: 1123366:TH3_RS09830
uniprot id: A0A0B4XUX1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1123366:TH3 RS17375
gene id: 1123366:TH3_RS17375
uniprot id: A0A0B4XZB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1123366:TH3 RS00535
gene id: 1123366:TH3_RS00535
uniprot id: A0A0B4XPD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1123366:TH3 RS15335
gene id: 1123366:TH3_RS15335
uniprot id: A0A0B4Y3C1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1123366:TH3 RS02450
gene id: 1123366:TH3_RS02450
uniprot id: A0A0B4XV15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS05255
gene id: 1123366:TH3_RS05255
uniprot id: A0A0B4XXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1123366:TH3 RS10685
gene id: 1123366:TH3_RS10685
uniprot id: A0A0B4XZE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123366:TH3 RS16560
gene id: 1123366:TH3_RS16560
uniprot id: A0A0B4XYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1123366:TH3 RS18940
gene id: 1123366:TH3_RS18940
uniprot id: A0A0B4Y596
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS19100
gene id: 1123366:TH3_RS19100
uniprot id: A0A0B4Y0B4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123366:TH3 RS01720
gene id: 1123366:TH3_RS01720
uniprot id: A0A0B4XW28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1123366:TH3 RS15725
gene id: 1123366:TH3_RS15725
uniprot id: A0A0B4Y3I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1123366:TH3 RS08105
gene id: 1123366:TH3_RS08105
uniprot id: A0A0B4XZ80
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1123366:TH3 RS03895
gene id: 1123366:TH3_RS03895
uniprot id: A0A0B4XX40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1123366:TH3 RS06045
gene id: 1123366:TH3_RS06045
uniprot id: A0A0B4XY10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1123366:TH3 RS06870
gene id: 1123366:TH3_RS06870
uniprot id: A0A0B4XYL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS15690
gene id: 1123366:TH3_RS15690
uniprot id: A0A0B4Y148
names: Similarity
messages: Belongs to the asparagine synthetase family.

1123366:TH3 RS14955
gene id: 1123366:TH3_RS14955
uniprot id: A0A0B4Y353
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1123366:TH3 RS10200
gene id: 1123366:TH3_RS10200
uniprot id: A0A0B4XY72
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1123366:TH3 RS13060
gene id: 1123366:TH3_RS13060
uniprot id: A0A0B4Y252
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS16925
gene id: 1123366:TH3_RS16925
uniprot id: A0A0B4Y2I7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1123366:TH3 RS07920
gene id: 1123366:TH3_RS07920
uniprot id: A0A0B4XWZ7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1123366:TH3 RS20560
gene id: 1123366:TH3_RS20560
uniprot id: A0A0B4Y164
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1123366:TH3 RS18490
gene id: 1123366:TH3_RS18490
uniprot id: A0A0B4Y523
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1123366:TH3 RS05820
gene id: 1123366:TH3_RS05820
uniprot id: A0A0B4XVN0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS20060
gene id: 1123366:TH3_RS20060
uniprot id: A0A0B4Y4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1123366:TH3 RS16110
gene id: 1123366:TH3_RS16110
uniprot id: A0A0B4Y234
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS03500
gene id: 1123366:TH3_RS03500
uniprot id: A0A0B4XWJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS09005
gene id: 1123366:TH3_RS09005
uniprot id: A0A0B4XUF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1123366:TH3 RS00695
gene id: 1123366:TH3_RS00695
uniprot id: A0A0B4XUA1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1123366:TH3 RS10460
gene id: 1123366:TH3_RS10460
uniprot id: A0A0B4XVA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1123366:TH3 RS19910
gene id: 1123366:TH3_RS19910
uniprot id: A0A0B4Y3P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1123366:TH3 RS07280
gene id: 1123366:TH3_RS07280
uniprot id: A0A0B4XZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1123366:TH3 RS07585
gene id: 1123366:TH3_RS07585
uniprot id: A0A0B4XYZ0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1123366:TH3 RS03785
gene id: 1123366:TH3_RS03785
uniprot id: A0A0B4XVN3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1123366:TH3 RS11690
gene id: 1123366:TH3_RS11690
uniprot id: A0A0B4Y1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1123366:TH3 RS03340
gene id: 1123366:TH3_RS03340
uniprot id: A0A0B4XWT3
names: Similarity
messages: Belongs to the peptidase U62 family.

1123366:TH3 RS06545
gene id: 1123366:TH3_RS06545
uniprot id: A0A0B4XYD3
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1123366:TH3 RS07370
gene id: 1123366:TH3_RS07370
uniprot id: A0A0B4XXJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1123366:TH3 RS16915
gene id: 1123366:TH3_RS16915
uniprot id: A0A0B4Y4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1123366:TH3 RS07135
gene id: 1123366:TH3_RS07135
uniprot id: A0A0B4XYZ9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1123366:TH3 RS06955
gene id: 1123366:TH3_RS06955
uniprot id: A0A0B4XXB5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS15990
gene id: 1123366:TH3_RS15990
uniprot id: A0A0B4Y1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1123366:TH3 RS09835
gene id: 1123366:TH3_RS09835
uniprot id: A0A0B4XYY5
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1123366:TH3 RS03305
gene id: 1123366:TH3_RS03305
uniprot id: A0A0B4XVG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS01805
gene id: 1123366:TH3_RS01805
uniprot id: A0A0B4XUS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS17085
gene id: 1123366:TH3_RS17085
uniprot id: A0A0B4Y4D3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1123366:TH3 RS12425
gene id: 1123366:TH3_RS12425
uniprot id: A0A0B4XWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1123366:TH3 RS06375
gene id: 1123366:TH3_RS06375
uniprot id: A0A0B4XSW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1123366:TH3 RS05795
gene id: 1123366:TH3_RS05795
uniprot id: A0A0B4XVM5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1123366:TH3 RS11490
gene id: 1123366:TH3_RS11490
uniprot id: A0A0B4Y167
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS20155
gene id: 1123366:TH3_RS20155
uniprot id: A0A0B4Y0Z2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1123366:TH3 RS12460
gene id: 1123366:TH3_RS12460
uniprot id: A0A0B4XZD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1123366:TH3 RS00350
gene id: 1123366:TH3_RS00350
uniprot id: A0A0B4XVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1123366:TH3 RS10290
gene id: 1123366:TH3_RS10290
uniprot id: A0A0B4XZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1123366:TH3 RS16215
gene id: 1123366:TH3_RS16215
uniprot id: A0A0B4Y1E4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS15360
gene id: 1123366:TH3_RS15360
uniprot id: A0A0B4Y3C6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1123366:TH3 RS17490
gene id: 1123366:TH3_RS17490
uniprot id: A0A0B4Y4L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1123366:TH3 RS19355
gene id: 1123366:TH3_RS19355
uniprot id: A0A0B4Y5H0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1123366:TH3 RS20550
gene id: 1123366:TH3_RS20550
uniprot id: A0A0B4Y6B7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1123366:TH3 RS06940
gene id: 1123366:TH3_RS06940
uniprot id: A0A0B4XYW5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS16920
gene id: 1123366:TH3_RS16920
uniprot id: A0A0B4XZ01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1123366:TH3 RS00430
gene id: 1123366:TH3_RS00430
uniprot id: A0A0B4XUM8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS03595
gene id: 1123366:TH3_RS03595
uniprot id: A0A0B4XWY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1123366:TH3 RS20325
gene id: 1123366:TH3_RS20325
uniprot id: A0A0B4Y640
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1123366:TH3 RS08165
gene id: 1123366:TH3_RS08165
uniprot id: A0A0B4XZJ7
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS08390
gene id: 1123366:TH3_RS08390
uniprot id: A0A0B4XZQ0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1123366:TH3 RS11095
gene id: 1123366:TH3_RS11095
uniprot id: A0A0B4XVN4
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS07310
gene id: 1123366:TH3_RS07310
uniprot id: A0A0B4XYT8
names: Similarity
messages: Belongs to the creatininase superfamily.

1123366:TH3 RS20170
gene id: 1123366:TH3_RS20170
uniprot id: A0A0B4Y644
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS11970
gene id: 1123366:TH3_RS11970
uniprot id: A0A0B4Y036
names: Similarity
messages: Belongs to the HesB/IscA family.

1123366:TH3 RS07915
gene id: 1123366:TH3_RS07915
uniprot id: A0A0B4XXU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS09770
gene id: 1123366:TH3_RS09770
uniprot id: A0A0B4Y0J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS00720
gene id: 1123366:TH3_RS00720
uniprot id: A0A0B4XUA6
names: Similarity
messages: Belongs to the fructosamine kinase family.

1123366:TH3 RS19060
gene id: 1123366:TH3_RS19060
uniprot id: A0A0B4Y357
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1123366:TH3 RS14120
gene id: 1123366:TH3_RS14120
uniprot id: A0A0B4Y0B0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1123366:TH3 RS06650
gene id: 1123366:TH3_RS06650
uniprot id: A0A0B4XT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS17835
gene id: 1123366:TH3_RS17835
uniprot id: A0A0B4Y2E0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1123366:TH3 RS12475
gene id: 1123366:TH3_RS12475
uniprot id: A0A0B4XWK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1123366:TH3 RS06195
gene id: 1123366:TH3_RS06195
uniprot id: A0A0B4XY49
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1123366:TH3 RS03555
gene id: 1123366:TH3_RS03555
uniprot id: A0A0B4XR56
names: Similarity
messages: Belongs to the arginase family.

1123366:TH3 RS14605
gene id: 1123366:TH3_RS14605
uniprot id: A0A0B4Y338
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS06585
gene id: 1123366:TH3_RS06585
uniprot id: A0A0B4XW70
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1123366:TH3 RS12190
gene id: 1123366:TH3_RS12190
uniprot id: A0A0B4XWF1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1123366:TH3 RS12220
gene id: 1123366:TH3_RS12220
uniprot id: A0A0B4Y062
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1123366:TH3 RS13160
gene id: 1123366:TH3_RS13160
uniprot id: A0A0B4Y271
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1123366:TH3 RS16480
gene id: 1123366:TH3_RS16480
uniprot id: A0A0B4Y400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1123366:TH3 RS05535
gene id: 1123366:TH3_RS05535
uniprot id: A0A0B4XWH4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1123366:TH3 RS05175
gene id: 1123366:TH3_RS05175
uniprot id: A0A0B4XV96
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1123366:TH3 RS07475
gene id: 1123366:TH3_RS07475
uniprot id: A0A0B4XXL4
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1123366:TH3 RS06630
gene id: 1123366:TH3_RS06630
uniprot id: A0A0B4XX27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1123366:TH3 RS02995
gene id: 1123366:TH3_RS02995
uniprot id: A0A0B4XW79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1123366:TH3 RS09365
gene id: 1123366:TH3_RS09365
uniprot id: A0A0B4XUN0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS19300
gene id: 1123366:TH3_RS19300
uniprot id: A0A0B4Y5K6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS09340
gene id: 1123366:TH3_RS09340
uniprot id: A0A0B4XUM7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1123366:TH3 RS16690
gene id: 1123366:TH3_RS16690
uniprot id: A0A0B4Y446
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1123366:TH3 RS14600
gene id: 1123366:TH3_RS14600
uniprot id: A0A0B4Y0L2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS16995
gene id: 1123366:TH3_RS16995
uniprot id: A0A0B4XZ42
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123366:TH3 RS16175
gene id: 1123366:TH3_RS16175
uniprot id: A0A0B4Y3S9
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1123366:TH3 RS22610
gene id: 1123366:TH3_RS22610
uniprot id: A0A0B4XUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

1123366:TH3 RS19410
gene id: 1123366:TH3_RS19410
uniprot id: A0A0B4Y0I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1123366:TH3 RS00515
gene id: 1123366:TH3_RS00515
uniprot id: A0A0B4XU60
names: Similarity
messages: Belongs to the GST superfamily.

1123366:TH3 RS17160
gene id: 1123366:TH3_RS17160
uniprot id: A0A0B4Y4E4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1123366:TH3 RS10555
gene id: 1123366:TH3_RS10555
uniprot id: A0A0B4XVC6
names: Similarity
messages: Belongs to the Skp family.

1123366:TH3 RS11080
gene id: 1123366:TH3_RS11080
uniprot id: A0A0B4XYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS15180
gene id: 1123366:TH3_RS15180
uniprot id: A0A0B4Y3D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS12725
gene id: 1123366:TH3_RS12725
uniprot id: A0A0B4Y1W0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS09420
gene id: 1123366:TH3_RS09420
uniprot id: A0A0B4XYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1123366:TH3 RS18810
gene id: 1123366:TH3_RS18810
uniprot id: A0A0B4Y591
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1123366:TH3 RS01345
gene id: 1123366:TH3_RS01345
uniprot id: A0A0B4XVV0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1123366:TH3 RS13010
gene id: 1123366:TH3_RS13010
uniprot id: A0A0B4Y241
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS01725
gene id: 1123366:TH3_RS01725
uniprot id: A0A0B4XVJ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1123366:TH3 RS12620
gene id: 1123366:TH3_RS12620
uniprot id: A0A0B4Y1U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1123366:TH3 RS08170
gene id: 1123366:TH3_RS08170
uniprot id: A0A0B4XZ91
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1123366:TH3 RS16900
gene id: 1123366:TH3_RS16900
uniprot id: A0A0B4Y2I1
names: Similarity
messages: Belongs to the sulfatase family.

1123366:TH3 RS11495
gene id: 1123366:TH3_RS11495
uniprot id: A0A0B4XVX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS03580
gene id: 1123366:TH3_RS03580
uniprot id: A0A0B4XR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1123366:TH3 RS06990
gene id: 1123366:TH3_RS06990
uniprot id: A0A0B4XYN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS04295
gene id: 1123366:TH3_RS04295
uniprot id: A0A0B4XXE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1123366:TH3 RS14590
gene id: 1123366:TH3_RS14590
uniprot id: A0A0B4XXU1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123366:TH3 RS09490
gene id: 1123366:TH3_RS09490
uniprot id: A0A0B4XXT9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1123366:TH3 RS00510
gene id: 1123366:TH3_RS00510
uniprot id: A0A0B4XPC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS11725
gene id: 1123366:TH3_RS11725
uniprot id: A0A0B4Y1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1123366:TH3 RS02360
gene id: 1123366:TH3_RS02360
uniprot id: A0A0B4XVU7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1123366:TH3 RS03890
gene id: 1123366:TH3_RS03890
uniprot id: A0A0B4XUG3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1123366:TH3 RS10030
gene id: 1123366:TH3_RS10030
uniprot id: A0A0B4Y094
names: Similarity
messages: Belongs to the CutA family.

1123366:TH3 RS16025
gene id: 1123366:TH3_RS16025
uniprot id: A0A0B4Y3P0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS10980
gene id: 1123366:TH3_RS10980
uniprot id: A0A0B4XYK0
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS13525
gene id: 1123366:TH3_RS13525
uniprot id: A0A0B4Y0V5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1123366:TH3 RS00600
gene id: 1123366:TH3_RS00600
uniprot id: A0A0B4XVF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1123366:TH3 RS06905
gene id: 1123366:TH3_RS06905
uniprot id: A0A0B4XXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1123366:TH3 RS15350
gene id: 1123366:TH3_RS15350
uniprot id: A0A0B4Y0Y4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1123366:TH3 RS04045
gene id: 1123366:TH3_RS04045
uniprot id: A0A0B4XUJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1123366:TH3 RS13350
gene id: 1123366:TH3_RS13350
uniprot id: A0A0B4Y0R9
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1123366:TH3 RS16810
gene id: 1123366:TH3_RS16810
uniprot id: A0A0B4Y468
names: Subcellular Location Annotation
messages: Mitochondrion

1123366:TH3 RS06030
gene id: 1123366:TH3_RS06030
uniprot id: A0A0B4XWS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1123366:TH3 RS03490
gene id: 1123366:TH3_RS03490
uniprot id: A0A0B4XU65
names: Similarity
messages: Belongs to the UPF0145 family.

1123366:TH3 RS12125
gene id: 1123366:TH3_RS12125
uniprot id: A0A0B4XZ78
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1123366:TH3 RS17225
gene id: 1123366:TH3_RS17225
uniprot id: A0A0B4Y2R6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1123366:TH3 RS05225
gene id: 1123366:TH3_RS05225
uniprot id: A0A0B4XVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1123366:TH3 RS12860
gene id: 1123366:TH3_RS12860
uniprot id: A0A0B4Y1Y1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1123366:TH3 RS22325
gene id: 1123366:TH3_RS22325
uniprot id: A0A0B4XWM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1123366:TH3 RS15190
gene id: 1123366:TH3_RS15190
uniprot id: A0A0B4XY25
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS10455
gene id: 1123366:TH3_RS10455
uniprot id: A0A0B4Y0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS00810
gene id: 1123366:TH3_RS00810
uniprot id: A0A0B4XVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS08980
gene id: 1123366:TH3_RS08980
uniprot id: A0A0B4XUE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1123366:TH3 RS16685
gene id: 1123366:TH3_RS16685
uniprot id: A0A0B4Y443
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS01080
gene id: 1123366:TH3_RS01080
uniprot id: A0A0B4XUF6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1123366:TH3 RS17930
gene id: 1123366:TH3_RS17930
uniprot id: A0A0B4Y331
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1123366:TH3 RS10130
gene id: 1123366:TH3_RS10130
uniprot id: A0A0B4Y0Q0
names: Similarity
messages: Belongs to the ros/MucR family.

1123366:TH3 RS15325
gene id: 1123366:TH3_RS15325
uniprot id: A0A0B4Y0X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1123366:TH3 RS17470
gene id: 1123366:TH3_RS17470
uniprot id: A0A0B4Y4I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1123366:TH3 RS08690
gene id: 1123366:TH3_RS08690
uniprot id: A0A0B4XXF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1123366:TH3 RS14860
gene id: 1123366:TH3_RS14860
uniprot id: A0A0B4XXX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1123366:TH3 RS00575
gene id: 1123366:TH3_RS00575
uniprot id: A0A0B4XVF2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1123366:TH3 RS11980
gene id: 1123366:TH3_RS11980
uniprot id: A0A0B4Y1M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1123366:TH3 RS18710
gene id: 1123366:TH3_RS18710
uniprot id: A0A0B4Y568
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1123366:TH3 RS10055
gene id: 1123366:TH3_RS10055
uniprot id: A0A0B4Y0N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1123366:TH3 RS00160
gene id: 1123366:TH3_RS00160
uniprot id: A0A0B4XP61
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS09605
gene id: 1123366:TH3_RS09605
uniprot id: A0A0B4XUR8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS02305
gene id: 1123366:TH3_RS02305
uniprot id: A0A0B4XW91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS09925
gene id: 1123366:TH3_RS09925
uniprot id: A0A0B4Y0L3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1123366:TH3 RS11845
gene id: 1123366:TH3_RS11845
uniprot id: A0A0B4XZ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS19395
gene id: 1123366:TH3_RS19395
uniprot id: A0A0B4Y3D9
names: Subcellular Location Annotation
messages: Nucleus

1123366:TH3 RS01325
gene id: 1123366:TH3_RS01325
uniprot id: A0A0B4XV97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1123366:TH3 RS20110
gene id: 1123366:TH3_RS20110
uniprot id: A0A0B4Y4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1123366:TH3 RS13515
gene id: 1123366:TH3_RS13515
uniprot id: A0A0B4Y2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS05775
gene id: 1123366:TH3_RS05775
uniprot id: A0A0B4XY61
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS09100
gene id: 1123366:TH3_RS09100
uniprot id: A0A0B4XZT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1123366:TH3 RS10725
gene id: 1123366:TH3_RS10725
uniprot id: A0A0B4Y0M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123366:TH3 RS17560
gene id: 1123366:TH3_RS17560
uniprot id: A0A0B4Y292
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1123366:TH3 RS18120
gene id: 1123366:TH3_RS18120
uniprot id: A0A0B4XZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1123366:TH3 RS05140
gene id: 1123366:TH3_RS05140
uniprot id: A0A0B4XS17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS21195
gene id: 1123366:TH3_RS21195
uniprot id: A0A0B4Y522
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1123366:TH3 RS12380
gene id: 1123366:TH3_RS12380
uniprot id: A0A0B4Y082
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1123366:TH3 RS20055
gene id: 1123366:TH3_RS20055
uniprot id: A0A0B4Y0X6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1123366:TH3 RS06910
gene id: 1123366:TH3_RS06910
uniprot id: A0A0B4XWG9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1123366:TH3 RS02035
gene id: 1123366:TH3_RS02035
uniprot id: A0A0B4XVP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1123366:TH3 RS07460
gene id: 1123366:TH3_RS07460
uniprot id: A0A0B4XZ55
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS09255
gene id: 1123366:TH3_RS09255
uniprot id: A0A0B4XZW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1123366:TH3 RS13185
gene id: 1123366:TH3_RS13185
uniprot id: A0A0B4Y276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS04610
gene id: 1123366:TH3_RS04610
uniprot id: A0A0B4XW22
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1123366:TH3 RS16985
gene id: 1123366:TH3_RS16985
uniprot id: A0A0B4Y4B9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS15270
gene id: 1123366:TH3_RS15270
uniprot id: A0A0B4Y1R2
names: Similarity
messages: Belongs to the CTP synthase family.

1123366:TH3 RS17485
gene id: 1123366:TH3_RS17485
uniprot id: A0A0B4Y282
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1123366:TH3 RS11265
gene id: 1123366:TH3_RS11265
uniprot id: A0A0B4Y113
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS10025
gene id: 1123366:TH3_RS10025
uniprot id: A0A0B4Y0M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1123366:TH3 RS06570
gene id: 1123366:TH3_RS06570
uniprot id: A0A0B4XYE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS06515
gene id: 1123366:TH3_RS06515
uniprot id: A0A0B4XYK8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1123366:TH3 RS08000
gene id: 1123366:TH3_RS08000
uniprot id: A0A0B4XZG5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1123366:TH3 RS08810
gene id: 1123366:TH3_RS08810
uniprot id: A0A0B4XYD1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS13600
gene id: 1123366:TH3_RS13600
uniprot id: A0A0B4Y0X7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1123366:TH3 RS05135
gene id: 1123366:TH3_RS05135
uniprot id: A0A0B4XXG2
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1123366:TH3 RS08705
gene id: 1123366:TH3_RS08705
uniprot id: A0A0B4XU85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1123366:TH3 RS07175
gene id: 1123366:TH3_RS07175
uniprot id: A0A0B4XXF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1123366:TH3 RS14405
gene id: 1123366:TH3_RS14405
uniprot id: A0A0B4Y2X0
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1123366:TH3 RS10960
gene id: 1123366:TH3_RS10960
uniprot id: A0A0B4Y131
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS15505
gene id: 1123366:TH3_RS15505
uniprot id: A0A0B4Y3H5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1123366:TH3 RS06690
gene id: 1123366:TH3_RS06690
uniprot id: A0A0B4XYS0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS05155
gene id: 1123366:TH3_RS05155
uniprot id: A0A0B4XXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS12635
gene id: 1123366:TH3_RS12635
uniprot id: A0A0B4XZH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1123366:TH3 RS06105
gene id: 1123366:TH3_RS06105
uniprot id: A0A0B4XWU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1123366:TH3 RS08010
gene id: 1123366:TH3_RS08010
uniprot id: A0A0B4XTV9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1123366:TH3 RS16600
gene id: 1123366:TH3_RS16600
uniprot id: A0A0B4Y1P0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1123366:TH3 RS07620
gene id: 1123366:TH3_RS07620
uniprot id: A0A0B4XTM6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS01590
gene id: 1123366:TH3_RS01590
uniprot id: A0A0B4XT95
names: Similarity
messages: Belongs to the UPF0235 family.

1123366:TH3 RS07215
gene id: 1123366:TH3_RS07215
uniprot id: A0A0B4XYR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1123366:TH3 RS20620
gene id: 1123366:TH3_RS20620
uniprot id: A0A0B4Y424
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS09640
gene id: 1123366:TH3_RS09640
uniprot id: A0A0B4XXW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1123366:TH3 RS10110
gene id: 1123366:TH3_RS10110
uniprot id: A0A0B4Y0A6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1123366:TH3 RS10770
gene id: 1123366:TH3_RS10770
uniprot id: A0A0B4XVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1123366:TH3 RS01460
gene id: 1123366:TH3_RS01460
uniprot id: A0A0B4XUK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1123366:TH3 RS19345
gene id: 1123366:TH3_RS19345
uniprot id: A0A0B4Y3C4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123366:TH3 RS20575
gene id: 1123366:TH3_RS20575
uniprot id: A0A0B4Y6C2
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1123366:TH3 RS20640
gene id: 1123366:TH3_RS20640
uniprot id: A0A0B4Y4R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS05060
gene id: 1123366:TH3_RS05060
uniprot id: A0A0B4XXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS06015
gene id: 1123366:TH3_RS06015
uniprot id: A0A0B4XYA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1123366:TH3 RS07305
gene id: 1123366:TH3_RS07305
uniprot id: A0A0B4XZ26
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS20040
gene id: 1123366:TH3_RS20040
uniprot id: A0A0B4Y3R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1123366:TH3 RS12590
gene id: 1123366:TH3_RS12590
uniprot id: A0A0B4Y1W4
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1123366:TH3 RS11755
gene id: 1123366:TH3_RS11755
uniprot id: A0A0B4XW68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1123366:TH3 RS17545
gene id: 1123366:TH3_RS17545
uniprot id: A0A0B4Y4J2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS11855
gene id: 1123366:TH3_RS11855
uniprot id: A0A0B4Y1F4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS10180
gene id: 1123366:TH3_RS10180
uniprot id: A0A0B4Y0Q7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123366:TH3 RS06850
gene id: 1123366:TH3_RS06850
uniprot id: A0A0B4XT88
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1123366:TH3 RS13230
gene id: 1123366:TH3_RS13230
uniprot id: A0A0B4XZU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1123366:TH3 RS03825
gene id: 1123366:TH3_RS03825
uniprot id: A0A0B4XWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1123366:TH3 RS06060
gene id: 1123366:TH3_RS06060
uniprot id: A0A0B4XVT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1123366:TH3 RS09675
gene id: 1123366:TH3_RS09675
uniprot id: A0A0B4Y023
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1123366:TH3 RS10245
gene id: 1123366:TH3_RS10245
uniprot id: A0A0B4XY80
names: Similarity
messages: Belongs to the MotB family.

1123366:TH3 RS10675
gene id: 1123366:TH3_RS10675
uniprot id: A0A0B4Y0L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123366:TH3 RS06010
gene id: 1123366:TH3_RS06010
uniprot id: A0A0B4XVS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1123366:TH3 RS17095
gene id: 1123366:TH3_RS17095
uniprot id: A0A0B4XZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS09850
gene id: 1123366:TH3_RS09850
uniprot id: A0A0B4Y060
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1123366:TH3 RS03630
gene id: 1123366:TH3_RS03630
uniprot id: A0A0B4XR70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1123366:TH3 RS18060
gene id: 1123366:TH3_RS18060
uniprot id: A0A0B4Y4W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1123366:TH3 RS16945
gene id: 1123366:TH3_RS16945
uniprot id: A0A0B4XZ25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1123366:TH3 RS18040
gene id: 1123366:TH3_RS18040
uniprot id: A0A0B4Y4R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1123366:TH3 RS13725
gene id: 1123366:TH3_RS13725
uniprot id: A0A0B4Y100
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1123366:TH3 RS12705
gene id: 1123366:TH3_RS12705
uniprot id: A0A0B4XWP6
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS18645
gene id: 1123366:TH3_RS18645
uniprot id: A0A0B4Y014
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1123366:TH3 RS21260
gene id: 1123366:TH3_RS21260
uniprot id: A0A0B4Y4F2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1123366:TH3 RS18115
gene id: 1123366:TH3_RS18115
uniprot id: A0A0B4Y4S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS20655
gene id: 1123366:TH3_RS20655
uniprot id: A0A0B4Y6A2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1123366:TH3 RS09685
gene id: 1123366:TH3_RS09685
uniprot id: A0A0B4XYV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1123366:TH3 RS02560
gene id: 1123366:TH3_RS02560
uniprot id: A0A0B4XWC2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS10620
gene id: 1123366:TH3_RS10620
uniprot id: A0A0B4Y0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1123366:TH3 RS09270
gene id: 1123366:TH3_RS09270
uniprot id: A0A0B4XXR5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS08205
gene id: 1123366:TH3_RS08205
uniprot id: A0A0B4XY02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS11825
gene id: 1123366:TH3_RS11825
uniprot id: A0A0B4Y1K8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1123366:TH3 RS17890
gene id: 1123366:TH3_RS17890
uniprot id: A0A0B4Y4T1
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1123366:TH3 RS15145
gene id: 1123366:TH3_RS15145
uniprot id: A0A0B4Y0U9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS17325
gene id: 1123366:TH3_RS17325
uniprot id: A0A0B4XZA5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1123366:TH3 RS20255
gene id: 1123366:TH3_RS20255
uniprot id: A0A0B4Y110
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1123366:TH3 RS14210
gene id: 1123366:TH3_RS14210
uniprot id: A0A0B4XXI7
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS00155
gene id: 1123366:TH3_RS00155
uniprot id: A0A0B4XUI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1123366:TH3 RS12370
gene id: 1123366:TH3_RS12370
uniprot id: A0A0B4Y1N8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS21095
gene id: 1123366:TH3_RS21095
uniprot id: A0A0B4Y6P6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1123366:TH3 RS02790
gene id: 1123366:TH3_RS02790
uniprot id: A0A0B4XTV6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1123366:TH3 RS01515
gene id: 1123366:TH3_RS01515
uniprot id: A0A0B4XT77
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1123366:TH3 RS06810
gene id: 1123366:TH3_RS06810
uniprot id: A0A0B4XWF4
names: Similarity
messages: Belongs to the universal stress protein A family.

1123366:TH3 RS20295
gene id: 1123366:TH3_RS20295
uniprot id: A0A0B4Y666
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS13910
gene id: 1123366:TH3_RS13910
uniprot id: A0A0B4Y077
names: Similarity
messages: Belongs to the IlvD/Edd family.

1123366:TH3 RS03140
gene id: 1123366:TH3_RS03140
uniprot id: A0A0B4XWP5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1123366:TH3 RS09035
gene id: 1123366:TH3_RS09035
uniprot id: A0A0B4XYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS21055
gene id: 1123366:TH3_RS21055
uniprot id: A0A0B4Y6H4
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1123366:TH3 RS10260
gene id: 1123366:TH3_RS10260
uniprot id: A0A0B4XV65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS07425
gene id: 1123366:TH3_RS07425
uniprot id: A0A0B4XXK5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS00950
gene id: 1123366:TH3_RS00950
uniprot id: A0A0B4XV07
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS04020
gene id: 1123366:TH3_RS04020
uniprot id: A0A0B4XUJ2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS12965
gene id: 1123366:TH3_RS12965
uniprot id: A0A0B4Y1Z8
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1123366:TH3 RS06050
gene id: 1123366:TH3_RS06050
uniprot id: A0A0B4XSM9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1123366:TH3 RS03165
gene id: 1123366:TH3_RS03165
uniprot id: A0A0B4XWQ0
names: Similarity
messages: Belongs to the CcdB toxin family.

1123366:TH3 RS06680
gene id: 1123366:TH3_RS06680
uniprot id: A0A0B4XX66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS12405
gene id: 1123366:TH3_RS12405
uniprot id: A0A0B4Y085
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS19000
gene id: 1123366:TH3_RS19000
uniprot id: A0A0B4Y092
names: Similarity
messages: Belongs to the peptidase C56 family.

1123366:TH3 RS00560
gene id: 1123366:TH3_RS00560
uniprot id: A0A0B4XPD8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS00080
gene id: 1123366:TH3_RS00080
uniprot id: A0A0B4XUH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS16905
gene id: 1123366:TH3_RS16905
uniprot id: A0A0B4Y1X7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS17070
gene id: 1123366:TH3_RS17070
uniprot id: A0A0B4Y2N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1123366:TH3 RS00250
gene id: 1123366:TH3_RS00250
uniprot id: A0A0B4XV83
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS13545
gene id: 1123366:TH3_RS13545
uniprot id: A0A0B4XX39
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1123366:TH3 RS03310
gene id: 1123366:TH3_RS03310
uniprot id: A0A0B4XU23
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123366:TH3 RS10590
gene id: 1123366:TH3_RS10590
uniprot id: A0A0B4XYE6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS16445
gene id: 1123366:TH3_RS16445
uniprot id: A0A0B4Y1J0
names: Similarity
messages: Belongs to the Ahb/Nir family.

1123366:TH3 RS19230
gene id: 1123366:TH3_RS19230
uniprot id: A0A0B4Y5E2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1123366:TH3 RS08420
gene id: 1123366:TH3_RS08420
uniprot id: A0A0B4XZE5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1123366:TH3 RS16170
gene id: 1123366:TH3_RS16170
uniprot id: A0A0B4Y3V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1123366:TH3 RS09175
gene id: 1123366:TH3_RS09175
uniprot id: A0A0B4Y080
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1123366:TH3 RS01585
gene id: 1123366:TH3_RS01585
uniprot id: A0A0B4XUM3
names: Similarity
messages: Belongs to the YggT family.

1123366:TH3 RS08785
gene id: 1123366:TH3_RS08785
uniprot id: A0A0B4XYC7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1123366:TH3 RS17880
gene id: 1123366:TH3_RS17880
uniprot id: A0A0B4Y321
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

1123366:TH3 RS19215
gene id: 1123366:TH3_RS19215
uniprot id: A0A0B4Y3U6
names: Similarity
messages: Belongs to the UPF0434 family.

1123366:TH3 RS03950
gene id: 1123366:TH3_RS03950
uniprot id: A0A0B4XX47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1123366:TH3 RS16890
gene id: 1123366:TH3_RS16890
uniprot id: A0A0B4Y495
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS16035
gene id: 1123366:TH3_RS16035
uniprot id: A0A0B4Y219
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS11165
gene id: 1123366:TH3_RS11165
uniprot id: A0A0B4Y0Y9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1123366:TH3 RS12410
gene id: 1123366:TH3_RS12410
uniprot id: A0A0B4XZC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS14230
gene id: 1123366:TH3_RS14230
uniprot id: A0A0B4Y2Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

1123366:TH3 RS11200
gene id: 1123366:TH3_RS11200
uniprot id: A0A0B4XZM2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1123366:TH3 RS09630
gene id: 1123366:TH3_RS09630
uniprot id: A0A0B4XUS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1123366:TH3 RS21285
gene id: 1123366:TH3_RS21285
uniprot id: A0A0B4Y6U6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1123366:TH3 RS06700
gene id: 1123366:TH3_RS06700
uniprot id: A0A0B4XT66
names: Similarity
messages: Belongs to the TlyA family.

1123366:TH3 RS20100
gene id: 1123366:TH3_RS20100
uniprot id: A0A0B4Y5Z1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1123366:TH3 RS14490
gene id: 1123366:TH3_RS14490
uniprot id: A0A0B4Y0J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS04065
gene id: 1123366:TH3_RS04065
uniprot id: A0A0B4XVU3
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1123366:TH3 RS02130
gene id: 1123366:TH3_RS02130
uniprot id: A0A0B4XW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1123366:TH3 RS08650
gene id: 1123366:TH3_RS08650
uniprot id: A0A0B4XZK0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS15125
gene id: 1123366:TH3_RS15125
uniprot id: A0A0B4Y3C2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1123366:TH3 RS15300
gene id: 1123366:TH3_RS15300
uniprot id: A0A0B4Y0X4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1123366:TH3 RS13860
gene id: 1123366:TH3_RS13860
uniprot id: A0A0B4Y064
names: Similarity
messages: Belongs to the IlvD/Edd family.

1123366:TH3 RS10530
gene id: 1123366:TH3_RS10530
uniprot id: A0A0B4XVC2
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1123366:TH3 RS03650
gene id: 1123366:TH3_RS03650
uniprot id: A0A0B4XWN0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1123366:TH3 RS13490
gene id: 1123366:TH3_RS13490
uniprot id: A0A0B4Y2A1
names: Similarity
messages: Belongs to the proline racemase family.

1123366:TH3 RS07040
gene id: 1123366:TH3_RS07040
uniprot id: A0A0B4XYP1
names: Similarity
messages: Belongs to the UPF0335 family.

1123366:TH3 RS12270
gene id: 1123366:TH3_RS12270
uniprot id: A0A0B4Y067
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1123366:TH3 RS08355
gene id: 1123366:TH3_RS08355
uniprot id: A0A0B4XX73
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1123366:TH3 RS00170
gene id: 1123366:TH3_RS00170
uniprot id: A0A0B4XSI2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS15020
gene id: 1123366:TH3_RS15020
uniprot id: A0A0B4Y0S3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1123366:TH3 RS00475
gene id: 1123366:TH3_RS00475
uniprot id: A0A0B4XVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1123366:TH3 RS18465
gene id: 1123366:TH3_RS18465
uniprot id: A0A0B4Y519
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS00595
gene id: 1123366:TH3_RS00595
uniprot id: A0A0B4XSQ0
names: Similarity
messages: Belongs to the TrpF family.

1123366:TH3 RS02350
gene id: 1123366:TH3_RS02350
uniprot id: A0A0B4XTP5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS15740
gene id: 1123366:TH3_RS15740
uniprot id: A0A0B4Y158
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1123366:TH3 RS15475
gene id: 1123366:TH3_RS15475
uniprot id: A0A0B4Y3E8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1123366:TH3 RS20180
gene id: 1123366:TH3_RS20180
uniprot id: A0A0B4Y0Z6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1123366:TH3 RS16860
gene id: 1123366:TH3_RS16860
uniprot id: A0A0B4Y477
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1123366:TH3 RS07035
gene id: 1123366:TH3_RS07035
uniprot id: A0A0B4XYY2
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1123366:TH3 RS16275
gene id: 1123366:TH3_RS16275
uniprot id: A0A0B4Y3W3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS19945
gene id: 1123366:TH3_RS19945
uniprot id: A0A0B4Y5V5
names: Similarity
messages: Belongs to the UPF0102 family.

1123366:TH3 RS20015
gene id: 1123366:TH3_RS20015
uniprot id: A0A0B4Y613
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1123366:TH3 RS11730
gene id: 1123366:TH3_RS11730
uniprot id: A0A0B4XW38
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1123366:TH3 RS01730
gene id: 1123366:TH3_RS01730
uniprot id: A0A0B4XQ72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1123366:TH3 RS08675
gene id: 1123366:TH3_RS08675
uniprot id: A0A0B4XZK6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS20335
gene id: 1123366:TH3_RS20335
uniprot id: A0A0B4Y4J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1123366:TH3 RS14215
gene id: 1123366:TH3_RS14215
uniprot id: A0A0B4Y1B6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS16725
gene id: 1123366:TH3_RS16725
uniprot id: A0A0B4Y2D8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS05785
gene id: 1123366:TH3_RS05785
uniprot id: A0A0B4XSG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1123366:TH3 RS03220
gene id: 1123366:TH3_RS03220
uniprot id: A0A0B4XWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS02085
gene id: 1123366:TH3_RS02085
uniprot id: A0A0B4XVQ6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1123366:TH3 RS01910
gene id: 1123366:TH3_RS01910
uniprot id: A0A0B4XW52
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS18330
gene id: 1123366:TH3_RS18330
uniprot id: A0A0B4Y3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1123366:TH3 RS11595
gene id: 1123366:TH3_RS11595
uniprot id: A0A0B4Y184
names: Similarity
messages: Belongs to the peptidase M1 family.

1123366:TH3 RS08680
gene id: 1123366:TH3_RS08680
uniprot id: A0A0B4XU82
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1123366:TH3 RS05455
gene id: 1123366:TH3_RS05455
uniprot id: A0A0B4XVE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS21140
gene id: 1123366:TH3_RS21140
uniprot id: A0A0B4Y1G8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS04160
gene id: 1123366:TH3_RS04160
uniprot id: A0A0B4XRJ6
names: Similarity
messages: Belongs to the pirin family.

1123366:TH3 RS10905
gene id: 1123366:TH3_RS10905
uniprot id: A0A0B4XYI7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1123366:TH3 RS18100
gene id: 1123366:TH3_RS18100
uniprot id: A0A0B4Y361
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1123366:TH3 RS14440
gene id: 1123366:TH3_RS14440
uniprot id: A0A0B4Y1H3
names: Similarity
messages: Belongs to the GSP E family.

1123366:TH3 RS03885
gene id: 1123366:TH3_RS03885
uniprot id: A0A0B4XVR1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1123366:TH3 RS05465
gene id: 1123366:TH3_RS05465
uniprot id: A0A0B4XXM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1123366:TH3 RS03995
gene id: 1123366:TH3_RS03995
uniprot id: A0A0B4XUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1123366:TH3 RS07275
gene id: 1123366:TH3_RS07275
uniprot id: A0A0B4XWN2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS05200
gene id: 1123366:TH3_RS05200
uniprot id: A0A0B4XVA0
names: Similarity
messages: Belongs to the UPF0178 family.

1123366:TH3 RS06985
gene id: 1123366:TH3_RS06985
uniprot id: A0A0B4XYX3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1123366:TH3 RS15370
gene id: 1123366:TH3_RS15370
uniprot id: A0A0B4Y1S6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS15910
gene id: 1123366:TH3_RS15910
uniprot id: A0A0B4XYE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS11635
gene id: 1123366:TH3_RS11635
uniprot id: A0A0B4XYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1123366:TH3 RS13950
gene id: 1123366:TH3_RS13950
uniprot id: A0A0B4Y2J8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1123366:TH3 RS07490
gene id: 1123366:TH3_RS07490
uniprot id: A0A0B4XYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS18715
gene id: 1123366:TH3_RS18715
uniprot id: A0A0B4Y545
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1123366:TH3 RS02820
gene id: 1123366:TH3_RS02820
uniprot id: A0A0B4XWH6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1123366:TH3 RS16325
gene id: 1123366:TH3_RS16325
uniprot id: A0A0B4Y3X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1123366:TH3 RS07980
gene id: 1123366:TH3_RS07980
uniprot id: A0A0B4XZ47
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1123366:TH3 RS20635
gene id: 1123366:TH3_RS20635
uniprot id: A0A0B4Y178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS16580
gene id: 1123366:TH3_RS16580
uniprot id: A0A0B4Y430
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1123366:TH3 RS20810
gene id: 1123366:TH3_RS20810
uniprot id: A0A0B4Y1B3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS13550
gene id: 1123366:TH3_RS13550
uniprot id: A0A0B4Y0W1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS07890
gene id: 1123366:TH3_RS07890
uniprot id: A0A0B4XZE2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123366:TH3 RS12905
gene id: 1123366:TH3_RS12905
uniprot id: A0A0B4Y218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1123366:TH3 RS03610
gene id: 1123366:TH3_RS03610
uniprot id: A0A0B4XVL1
names: Similarity
messages: Belongs to the BolA/IbaG family.

1123366:TH3 RS19030
gene id: 1123366:TH3_RS19030
uniprot id: A0A0B4Y3Q5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1123366:TH3 RS04000
gene id: 1123366:TH3_RS04000
uniprot id: A0A0B4XX57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1123366:TH3 RS07140
gene id: 1123366:TH3_RS07140
uniprot id: A0A0B4XYQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1123366:TH3 RS09370
gene id: 1123366:TH3_RS09370
uniprot id: A0A0B4XYR2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS06215
gene id: 1123366:TH3_RS06215
uniprot id: A0A0B4XYE8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1123366:TH3 RS05375
gene id: 1123366:TH3_RS05375
uniprot id: A0A0B4XWE4
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS19140
gene id: 1123366:TH3_RS19140
uniprot id: A0A0B4Y5H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1123366:TH3 RS13610
gene id: 1123366:TH3_RS13610
uniprot id: A0A0B4Y2F5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1123366:TH3 RS16345
gene id: 1123366:TH3_RS16345
uniprot id: A0A0B4Y1G4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1123366:TH3 RS11190
gene id: 1123366:TH3_RS11190
uniprot id: A0A0B4Y0Z3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS16185
gene id: 1123366:TH3_RS16185
uniprot id: A0A0B4Y246
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1123366:TH3 RS08400
gene id: 1123366:TH3_RS08400
uniprot id: A0A0B4XU40
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS17715
gene id: 1123366:TH3_RS17715
uniprot id: A0A0B4Y4Q3
names: Similarity
messages: Belongs to the peptidase M16 family.

1123366:TH3 RS15120
gene id: 1123366:TH3_RS15120
uniprot id: A0A0B4Y0U5
names: Similarity
messages: Belongs to the SfsA family.

1123366:TH3 RS19905
gene id: 1123366:TH3_RS19905
uniprot id: A0A0B4Y4B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1123366:TH3 RS08920
gene id: 1123366:TH3_RS08920
uniprot id: A0A0B4Y013
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS10895
gene id: 1123366:TH3_RS10895
uniprot id: A0A0B4XVI6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123366:TH3 RS02020
gene id: 1123366:TH3_RS02020
uniprot id: A0A0B4XUV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1123366:TH3 RS19760
gene id: 1123366:TH3_RS19760
uniprot id: A0A0B4Y5V4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS13785
gene id: 1123366:TH3_RS13785
uniprot id: A0A0B4Y2J5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1123366:TH3 RS02315
gene id: 1123366:TH3_RS02315
uniprot id: A0A0B4XQG9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS16790
gene id: 1123366:TH3_RS16790
uniprot id: A0A0B4Y469
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1123366:TH3 RS06155
gene id: 1123366:TH3_RS06155
uniprot id: A0A0B4XWV3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS03605
gene id: 1123366:TH3_RS03605
uniprot id: A0A0B4XR65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1123366:TH3 RS17260
gene id: 1123366:TH3_RS17260
uniprot id: A0A0B4Y4G6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123366:TH3 RS09010
gene id: 1123366:TH3_RS09010
uniprot id: A0A0B4XYH4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1123366:TH3 RS05885
gene id: 1123366:TH3_RS05885
uniprot id: A0A0B4XSJ3
names: Similarity
messages: Belongs to the UPF0229 family.

1123366:TH3 RS00645
gene id: 1123366:TH3_RS00645
uniprot id: A0A0B4XU93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1123366:TH3 RS04995
gene id: 1123366:TH3_RS04995
uniprot id: A0A0B4XW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS16520
gene id: 1123366:TH3_RS16520
uniprot id: A0A0B4Y1L3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS04195
gene id: 1123366:TH3_RS04195
uniprot id: A0A0B4XUP2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1123366:TH3 RS03110
gene id: 1123366:TH3_RS03110
uniprot id: A0A0B4XTZ4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1123366:TH3 RS09610
gene id: 1123366:TH3_RS09610
uniprot id: A0A0B4XYU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1123366:TH3 RS03990
gene id: 1123366:TH3_RS03990
uniprot id: A0A0B4XVT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1123366:TH3 RS07375
gene id: 1123366:TH3_RS07375
uniprot id: A0A0B4XWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1123366:TH3 RS07610
gene id: 1123366:TH3_RS07610
uniprot id: A0A0B4XZ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS10085
gene id: 1123366:TH3_RS10085
uniprot id: A0A0B4Y0A1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1123366:TH3 RS01940
gene id: 1123366:TH3_RS01940
uniprot id: A0A0B4XVN2
names: Similarity
messages: Belongs to the Gfa family.

1123366:TH3 RS13520
gene id: 1123366:TH3_RS13520
uniprot id: A0A0B4XX34
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1123366:TH3 RS13560
gene id: 1123366:TH3_RS13560
uniprot id: A0A0B4Y2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS14930
gene id: 1123366:TH3_RS14930
uniprot id: A0A0B4Y348
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1123366:TH3 RS05270
gene id: 1123366:TH3_RS05270
uniprot id: A0A0B4XWC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1123366:TH3 RS13165
gene id: 1123366:TH3_RS13165
uniprot id: A0A0B4Y238
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1123366:TH3 RS07830
gene id: 1123366:TH3_RS07830
uniprot id: A0A0B4XXS9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1123366:TH3 RS16135
gene id: 1123366:TH3_RS16135
uniprot id: A0A0B4Y236
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS02105
gene id: 1123366:TH3_RS02105
uniprot id: A0A0B4XW75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1123366:TH3 RS09875
gene id: 1123366:TH3_RS09875
uniprot id: A0A0B4Y066
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1123366:TH3 RS17000
gene id: 1123366:TH3_RS17000
uniprot id: A0A0B4Y2M5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1123366:TH3 RS19705
gene id: 1123366:TH3_RS19705
uniprot id: A0A0B4Y3K9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS19700
gene id: 1123366:TH3_RS19700
uniprot id: A0A0B4Y479
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1123366:TH3 RS16535
gene id: 1123366:TH3_RS16535
uniprot id: A0A0B4XYQ7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1123366:TH3 RS05640
gene id: 1123366:TH3_RS05640
uniprot id: A0A0B4XWJ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS08945
gene id: 1123366:TH3_RS08945
uniprot id: A0A0B4Y019
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1123366:TH3 RS11945
gene id: 1123366:TH3_RS11945
uniprot id: A0A0B4Y033
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1123366:TH3 RS05030
gene id: 1123366:TH3_RS05030
uniprot id: A0A0B4XXS0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS15220
gene id: 1123366:TH3_RS15220
uniprot id: A0A0B4Y1Q7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1123366:TH3 RS11985
gene id: 1123366:TH3_RS11985
uniprot id: A0A0B4Y1G9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1123366:TH3 RS09540
gene id: 1123366:TH3_RS09540
uniprot id: A0A0B4XXU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1123366:TH3 RS16755
gene id: 1123366:TH3_RS16755
uniprot id: A0A0B4Y1T8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1123366:TH3 RS14980
gene id: 1123366:TH3_RS14980
uniprot id: A0A0B4Y358
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1123366:TH3 RS01475
gene id: 1123366:TH3_RS01475
uniprot id: A0A0B4XVC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1123366:TH3 RS03795
gene id: 1123366:TH3_RS03795
uniprot id: A0A0B4XX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1123366:TH3 RS17810
gene id: 1123366:TH3_RS17810
uniprot id: A0A0B4Y2D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1123366:TH3 RS20650
gene id: 1123366:TH3_RS20650
uniprot id: A0A0B4Y6E0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS19445
gene id: 1123366:TH3_RS19445
uniprot id: A0A0B4Y3E6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS12215
gene id: 1123366:TH3_RS12215
uniprot id: A0A0B4XWF6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1123366:TH3 RS07635
gene id: 1123366:TH3_RS07635
uniprot id: A0A0B4XZ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS09240
gene id: 1123366:TH3_RS09240
uniprot id: A0A0B4XUL6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS16935
gene id: 1123366:TH3_RS16935
uniprot id: A0A0B4Y496
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

1123366:TH3 RS17500
gene id: 1123366:TH3_RS17500
uniprot id: A0A0B4XZE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1123366:TH3 RS09060
gene id: 1123366:TH3_RS09060
uniprot id: A0A0B4XYI1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1123366:TH3 RS20350
gene id: 1123366:TH3_RS20350
uniprot id: A0A0B4Y646
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS12730
gene id: 1123366:TH3_RS12730
uniprot id: A0A0B4XWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS11650
gene id: 1123366:TH3_RS11650
uniprot id: A0A0B4XW11
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS02765
gene id: 1123366:TH3_RS02765
uniprot id: A0A0B4XWG3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1123366:TH3 RS13780
gene id: 1123366:TH3_RS13780
uniprot id: A0A0B4Y044
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS08510
gene id: 1123366:TH3_RS08510
uniprot id: A0A0B4XXA4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS14920
gene id: 1123366:TH3_RS14920
uniprot id: A0A0B4Y0Q1
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1123366:TH3 RS11720
gene id: 1123366:TH3_RS11720
uniprot id: A0A0B4Y1F2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1123366:TH3 RS03075
gene id: 1123366:TH3_RS03075
uniprot id: A0A0B4XQW9
names: Similarity
messages: Belongs to the GARS family.

1123366:TH3 RS07010
gene id: 1123366:TH3_RS07010
uniprot id: A0A0B4XYX8
names: Similarity
messages: Belongs to the hyi family.

1123366:TH3 RS09315
gene id: 1123366:TH3_RS09315
uniprot id: A0A0B4XUM4
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1123366:TH3 RS09210
gene id: 1123366:TH3_RS09210
uniprot id: A0A0B4XUL4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1123366:TH3 RS16045
gene id: 1123366:TH3_RS16045
uniprot id: A0A0B4Y3S6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS11975
gene id: 1123366:TH3_RS11975
uniprot id: A0A0B4XZ53
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1123366:TH3 RS17285
gene id: 1123366:TH3_RS17285
uniprot id: A0A0B4Y4H3
names: Similarity
messages: Belongs to the Gfa family.

1123366:TH3 RS12550
gene id: 1123366:TH3_RS12550
uniprot id: A0A0B4XWL6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1123366:TH3 RS15650
gene id: 1123366:TH3_RS15650
uniprot id: A0A0B4Y3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1123366:TH3 RS06735
gene id: 1123366:TH3_RS06735
uniprot id: A0A0B4XWD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1123366:TH3 RS20780
gene id: 1123366:TH3_RS20780
uniprot id: A0A0B4Y6C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1123366:TH3 RS16750
gene id: 1123366:TH3_RS16750
uniprot id: A0A0B4Y2E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1123366:TH3 RS18845
gene id: 1123366:TH3_RS18845
uniprot id: A0A0B4Y063
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1123366:TH3 RS13660
gene id: 1123366:TH3_RS13660
uniprot id: A0A0B4Y2G7
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

1123366:TH3 RS23025
gene id: 1123366:TH3_RS23025
uniprot id: A0A0B4XW44
names: Similarity
messages: Belongs to the 2Fe2S plant-type ferredoxin family.
messages: Belongs to the glycosyl hydrolase 24 family.

1123366:TH3 RS02045
gene id: 1123366:TH3_RS02045
uniprot id: A0A0B4XUV8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS08595
gene id: 1123366:TH3_RS08595
uniprot id: A0A0B4XZI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS01145
gene id: 1123366:TH3_RS01145
uniprot id: A0A0B4XV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1123366:TH3 RS02470
gene id: 1123366:TH3_RS02470
uniprot id: A0A0B4XQJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS10240
gene id: 1123366:TH3_RS10240
uniprot id: A0A0B4XZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1123366:TH3 RS09635
gene id: 1123366:TH3_RS09635
uniprot id: A0A0B4XYU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1123366:TH3 RS09190
gene id: 1123366:TH3_RS09190
uniprot id: A0A0B4XYN1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123366:TH3 RS03700
gene id: 1123366:TH3_RS03700
uniprot id: A0A0B4XWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS00010
gene id: 1123366:TH3_RS00010
uniprot id: A0A0B4XUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1123366:TH3 RS07970
gene id: 1123366:TH3_RS07970
uniprot id: A0A0B4XX05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1123366:TH3 RS10990
gene id: 1123366:TH3_RS10990
uniprot id: A0A0B4Y0U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS20045
gene id: 1123366:TH3_RS20045
uniprot id: A0A0B4Y620
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1123366:TH3 RS20165
gene id: 1123366:TH3_RS20165
uniprot id: A0A0B4Y3T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1123366:TH3 RS09055
gene id: 1123366:TH3_RS09055
uniprot id: A0A0B4XUG4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1123366:TH3 RS14995
gene id: 1123366:TH3_RS14995
uniprot id: A0A0B4Y0R7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1123366:TH3 RS18955
gene id: 1123366:TH3_RS18955
uniprot id: A0A0B4Y327
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS12640
gene id: 1123366:TH3_RS12640
uniprot id: A0A0B4Y1X4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1123366:TH3 RS06095
gene id: 1123366:TH3_RS06095
uniprot id: A0A0B4XY24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1123366:TH3 RS06025
gene id: 1123366:TH3_RS06025
uniprot id: A0A0B4XSM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1123366:TH3 RS13145
gene id: 1123366:TH3_RS13145
uniprot id: A0A0B4XWW6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS01320
gene id: 1123366:TH3_RS01320
uniprot id: A0A0B4XVU4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1123366:TH3 RS10400
gene id: 1123366:TH3_RS10400
uniprot id: A0A0B4Y0T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1123366:TH3 RS01710
gene id: 1123366:TH3_RS01710
uniprot id: A0A0B4XUR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1123366:TH3 RS11290
gene id: 1123366:TH3_RS11290
uniprot id: A0A0B4Y122
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1123366:TH3 RS19995
gene id: 1123366:TH3_RS19995
uniprot id: A0A0B4Y5W6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1123366:TH3 RS04670
gene id: 1123366:TH3_RS04670
uniprot id: A0A0B4XXK7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS13195
gene id: 1123366:TH3_RS13195
uniprot id: A0A0B4XWX8
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1123366:TH3 RS10270
gene id: 1123366:TH3_RS10270
uniprot id: A0A0B4XY87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1123366:TH3 RS03450
gene id: 1123366:TH3_RS03450
uniprot id: A0A0B4XWI3
names: Similarity
messages: Belongs to the IMPACT family.

1123366:TH3 RS09865
gene id: 1123366:TH3_RS09865
uniprot id: A0A0B4XY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS12885
gene id: 1123366:TH3_RS12885
uniprot id: A0A0B4Y1Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1123366:TH3 RS09555
gene id: 1123366:TH3_RS09555
uniprot id: A0A0B4XUQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1123366:TH3 RS03420
gene id: 1123366:TH3_RS03420
uniprot id: A0A0B4XWV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.
messages: Homotrimer.

1123366:TH3 RS15040
gene id: 1123366:TH3_RS15040
uniprot id: A0A0B4Y1N3
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1123366:TH3 RS16225
gene id: 1123366:TH3_RS16225
uniprot id: A0A0B4Y3U1
names: Similarity
messages: Belongs to the peptidase M24B family.

1123366:TH3 RS19480
gene id: 1123366:TH3_RS19480
uniprot id: A0A0B4Y5P3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1123366:TH3 RS13980
gene id: 1123366:TH3_RS13980
uniprot id: A0A0B4XXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123366:TH3 RS14240
gene id: 1123366:TH3_RS14240
uniprot id: A0A0B4Y1C1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123366:TH3 RS15470
gene id: 1123366:TH3_RS15470
uniprot id: A0A0B4Y3H3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1123366:TH3 RS09840
gene id: 1123366:TH3_RS09840
uniprot id: A0A0B4XY08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1123366:TH3 RS09115
gene id: 1123366:TH3_RS09115
uniprot id: A0A0B4XXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

1123366:TH3 RS03920
gene id: 1123366:TH3_RS03920
uniprot id: A0A0B4XX43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1123366:TH3 RS20585
gene id: 1123366:TH3_RS20585
uniprot id: A0A0B4Y169
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1123366:TH3 RS07855
gene id: 1123366:TH3_RS07855
uniprot id: A0A0B4XXT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123366:TH3 RS16555
gene id: 1123366:TH3_RS16555
uniprot id: A0A0B4Y419
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1123366:TH3 RS21190
gene id: 1123366:TH3_RS21190
uniprot id: A0A0B4Y1I2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1123366:TH3 RS02325
gene id: 1123366:TH3_RS02325
uniprot id: A0A0B4XTP2
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1123366:TH3 RS00230
gene id: 1123366:TH3_RS00230
uniprot id: A0A0B4XUK1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS07670
gene id: 1123366:TH3_RS07670
uniprot id: A0A0B4XXP4
names: Similarity
messages: Belongs to the UPF0047 family.

1123366:TH3 RS18425
gene id: 1123366:TH3_RS18425
uniprot id: A0A0B4XZX6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS10945
gene id: 1123366:TH3_RS10945
uniprot id: A0A0B4XVJ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123366:TH3 RS20490
gene id: 1123366:TH3_RS20490
uniprot id: A0A0B4Y4N1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS08565
gene id: 1123366:TH3_RS08565
uniprot id: A0A0B4XZU1
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1123366:TH3 RS14080
gene id: 1123366:TH3_RS14080
uniprot id: A0A0B4Y2L9
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS00355
gene id: 1123366:TH3_RS00355
uniprot id: A0A0B4XUL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1123366:TH3 RS00245
gene id: 1123366:TH3_RS00245
uniprot id: A0A0B4XSJ5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS17595
gene id: 1123366:TH3_RS17595
uniprot id: A0A0B4Y4K0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS19450
gene id: 1123366:TH3_RS19450
uniprot id: A0A0B4Y5M8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1123366:TH3 RS00200
gene id: 1123366:TH3_RS00200
uniprot id: A0A0B4XV74
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1123366:TH3 RS05915
gene id: 1123366:TH3_RS05915
uniprot id: A0A0B4XWQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS20420
gene id: 1123366:TH3_RS20420
uniprot id: A0A0B4Y3Y9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1123366:TH3 RS10775
gene id: 1123366:TH3_RS10775
uniprot id: A0A0B4XZF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1123366:TH3 RS16155
gene id: 1123366:TH3_RS16155
uniprot id: A0A0B4XYJ3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123366:TH3 RS01235
gene id: 1123366:TH3_RS01235
uniprot id: A0A0B4XT21
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS09905
gene id: 1123366:TH3_RS09905
uniprot id: A0A0B4Y072
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1123366:TH3 RS16150
gene id: 1123366:TH3_RS16150
uniprot id: A0A0B4Y3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS16090
gene id: 1123366:TH3_RS16090
uniprot id: A0A0B4Y1C3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1123366:TH3 RS11785
gene id: 1123366:TH3_RS11785
uniprot id: A0A0B4XW82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1123366:TH3 RS19515
gene id: 1123366:TH3_RS19515
uniprot id: A0A0B4Y0N8
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1123366:TH3 RS15070
gene id: 1123366:TH3_RS15070
uniprot id: A0A0B4Y0T5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1123366:TH3 RS02180
gene id: 1123366:TH3_RS02180
uniprot id: A0A0B4XW81
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1123366:TH3 RS03685
gene id: 1123366:TH3_RS03685
uniprot id: A0A0B4XVM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS11700
gene id: 1123366:TH3_RS11700
uniprot id: A0A0B4XZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1123366:TH3 RS05540
gene id: 1123366:TH3_RS05540
uniprot id: A0A0B4XVG9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS22425
gene id: 1123366:TH3_RS22425
uniprot id: A0A0B4Y0E8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS05685
gene id: 1123366:TH3_RS05685
uniprot id: A0A0B4XSE6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS16475
gene id: 1123366:TH3_RS16475
uniprot id: A0A0B4Y408
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1123366:TH3 RS06055
gene id: 1123366:TH3_RS06055
uniprot id: A0A0B4XWT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1123366:TH3 RS06470
gene id: 1123366:TH3_RS06470
uniprot id: A0A0B4XYK3
names: Similarity
messages: Belongs to the ArsC family.

1123366:TH3 RS14975
gene id: 1123366:TH3_RS14975
uniprot id: A0A0B4Y396
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1123366:TH3 RS05385
gene id: 1123366:TH3_RS05385
uniprot id: A0A0B4XY00
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1123366:TH3 RS05920
gene id: 1123366:TH3_RS05920
uniprot id: A0A0B4XVQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS17390
gene id: 1123366:TH3_RS17390
uniprot id: A0A0B4Y4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS21150
gene id: 1123366:TH3_RS21150
uniprot id: A0A0B4Y4C4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1123366:TH3 RS16145
gene id: 1123366:TH3_RS16145
uniprot id: A0A0B4Y3U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS12145
gene id: 1123366:TH3_RS12145
uniprot id: A0A0B4Y053
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1123366:TH3 RS20700
gene id: 1123366:TH3_RS20700
uniprot id: A0A0B4Y6F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1123366:TH3 RS22545
gene id: 1123366:TH3_RS22545
uniprot id: A0A0B4Y5I7
names: Similarity
messages: Belongs to the GSP E family.

1123366:TH3 RS08815
gene id: 1123366:TH3_RS08815
uniprot id: A0A0B4XXH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS20160
gene id: 1123366:TH3_RS20160
uniprot id: A0A0B4Y4F3
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1123366:TH3 RS15610
gene id: 1123366:TH3_RS15610
uniprot id: A0A0B4Y1V8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS17745
gene id: 1123366:TH3_RS17745
uniprot id: A0A0B4Y4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS01250
gene id: 1123366:TH3_RS01250
uniprot id: A0A0B4XPV1
names: Similarity
messages: Belongs to the CFA/CMAS family.

1123366:TH3 RS18690
gene id: 1123366:TH3_RS18690
uniprot id: A0A0B4Y537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1123366:TH3 RS20050
gene id: 1123366:TH3_RS20050
uniprot id: A0A0B4Y5X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1123366:TH3 RS02780
gene id: 1123366:TH3_RS02780
uniprot id: A0A0B4XQQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1123366:TH3 RS08940
gene id: 1123366:TH3_RS08940
uniprot id: A0A0B4XXK3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS21155
gene id: 1123366:TH3_RS21155
uniprot id: A0A0B4Y6Q9
names: Similarity
messages: Belongs to the peptidase S49 family.

1123366:TH3 RS22315
gene id: 1123366:TH3_RS22315
uniprot id: A0A0B4XZ03
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS07390
gene id: 1123366:TH3_RS07390
uniprot id: A0A0B4XTI1
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.

1123366:TH3 RS03035
gene id: 1123366:TH3_RS03035
uniprot id: A0A0B4XTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1123366:TH3 RS10225
gene id: 1123366:TH3_RS10225
uniprot id: A0A0B4Y0R3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123366:TH3 RS21180
gene id: 1123366:TH3_RS21180
uniprot id: A0A0B4Y6R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS03440
gene id: 1123366:TH3_RS03440
uniprot id: A0A0B4XU52
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1123366:TH3 RS14400
gene id: 1123366:TH3_RS14400
uniprot id: A0A0B4Y306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1123366:TH3 RS19370
gene id: 1123366:TH3_RS19370
uniprot id: A0A0B4Y3C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1123366:TH3 RS01645
gene id: 1123366:TH3_RS01645
uniprot id: A0A0B4XW19
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123366:TH3 RS19160
gene id: 1123366:TH3_RS19160
uniprot id: A0A0B4Y382
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1123366:TH3 RS02530
gene id: 1123366:TH3_RS02530
uniprot id: A0A0B4XTR3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS04235
gene id: 1123366:TH3_RS04235
uniprot id: A0A0B4XVY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS18660
gene id: 1123366:TH3_RS18660
uniprot id: A0A0B4Y558
names: Similarity
messages: Belongs to the allantoicase family.

1123366:TH3 RS01430
gene id: 1123366:TH3_RS01430
uniprot id: A0A0B4XPZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1123366:TH3 RS09510
gene id: 1123366:TH3_RS09510
uniprot id: A0A0B4XYT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1123366:TH3 RS02380
gene id: 1123366:TH3_RS02380
uniprot id: A0A0B4XW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS23370
gene id: 1123366:TH3_RS23370
uniprot id: A0A0B4Y0M2
names: Similarity
messages: Belongs to the SDHAF4 family.

1123366:TH3 RS03665
gene id: 1123366:TH3_RS03665
uniprot id: A0A0B4XUA9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1123366:TH3 RS01530
gene id: 1123366:TH3_RS01530
uniprot id: A0A0B4XQ13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS00175
gene id: 1123366:TH3_RS00175
uniprot id: A0A0B4XV68
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS02885
gene id: 1123366:TH3_RS02885
uniprot id: A0A0B4XQS5
names: Similarity
messages: Belongs to the HSP15 family.

1123366:TH3 RS10010
gene id: 1123366:TH3_RS10010
uniprot id: A0A0B4XV11
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1123366:TH3 RS01085
gene id: 1123366:TH3_RS01085
uniprot id: A0A0B4XSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS07365
gene id: 1123366:TH3_RS07365
uniprot id: A0A0B4XTH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS13410
gene id: 1123366:TH3_RS13410
uniprot id: A0A0B4Y293
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1123366:TH3 RS08685
gene id: 1123366:TH3_RS08685
uniprot id: A0A0B4XYB1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1123366:TH3 RS14305
gene id: 1123366:TH3_RS14305
uniprot id: A0A0B4Y2S6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS17840
gene id: 1123366:TH3_RS17840
uniprot id: A0A0B4Y4S5
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1123366:TH3 RS17730
gene id: 1123366:TH3_RS17730
uniprot id: A0A0B4Y2Z4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1123366:TH3 RS04360
gene id: 1123366:TH3_RS04360
uniprot id: A0A0B4XW00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1123366:TH3 RS12465
gene id: 1123366:TH3_RS12465
uniprot id: A0A0B4Y1U7
names: Similarity
messages: Belongs to the fabD family.

1123366:TH3 RS09085
gene id: 1123366:TH3_RS09085
uniprot id: A0A0B4XYI3
names: Subcellular Location Annotation
messages: Cell membrane

1123366:TH3 RS06150
gene id: 1123366:TH3_RS06150
uniprot id: A0A0B4XSQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1123366:TH3 RS17445
gene id: 1123366:TH3_RS17445
uniprot id: A0A0B4Y4I1
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS20905
gene id: 1123366:TH3_RS20905
uniprot id: A0A0B4Y6E3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1123366:TH3 RS06135
gene id: 1123366:TH3_RS06135
uniprot id: A0A0B4XVU9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1123366:TH3 RS00435
gene id: 1123366:TH3_RS00435
uniprot id: A0A0B4XPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS19055
gene id: 1123366:TH3_RS19055
uniprot id: A0A0B4Y3R1
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1123366:TH3 RS11365
gene id: 1123366:TH3_RS11365
uniprot id: A0A0B4Y141
names: Similarity
messages: Belongs to the TPP enzyme family.

1123366:TH3 RS02455
gene id: 1123366:TH3_RS02455
uniprot id: A0A0B4XTQ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS20535
gene id: 1123366:TH3_RS20535
uniprot id: A0A0B4Y159
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1123366:TH3 RS19235
gene id: 1123366:TH3_RS19235
uniprot id: A0A0B4Y0E5
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1123366:TH3 RS10275
gene id: 1123366:TH3_RS10275
uniprot id: A0A0B4Y0R8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1123366:TH3 RS07465
gene id: 1123366:TH3_RS07465
uniprot id: A0A0B4XYW7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS10835
gene id: 1123366:TH3_RS10835
uniprot id: A0A0B4Y114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS18510
gene id: 1123366:TH3_RS18510
uniprot id: A0A0B4Y2S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1123366:TH3 RS10000
gene id: 1123366:TH3_RS10000
uniprot id: A0A0B4Y0M5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1123366:TH3 RS20365
gene id: 1123366:TH3_RS20365
uniprot id: A0A0B4Y3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1123366:TH3 RS22165
gene id: 1123366:TH3_RS22165
uniprot id: A0A0B4Y574
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1123366:TH3 RS06160
gene id: 1123366:TH3_RS06160
uniprot id: A0A0B4XVV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1123366:TH3 RS12015
gene id: 1123366:TH3_RS12015
uniprot id: A0A0B4XWC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS09105
gene id: 1123366:TH3_RS09105
uniprot id: A0A0B4XUH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Membrane

1123366:TH3 RS06130
gene id: 1123366:TH3_RS06130
uniprot id: A0A0B4XWU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1123366:TH3 RS13800
gene id: 1123366:TH3_RS13800
uniprot id: A0A0B4XX90
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS10125
gene id: 1123366:TH3_RS10125
uniprot id: A0A0B4XY57
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1123366:TH3 RS05690
gene id: 1123366:TH3_RS05690
uniprot id: A0A0B4XWK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS07715
gene id: 1123366:TH3_RS07715
uniprot id: A0A0B4XTP6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1123366:TH3 RS20145
gene id: 1123366:TH3_RS20145
uniprot id: A0A0B4Y639
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1123366:TH3 RS17410
gene id: 1123366:TH3_RS17410
uniprot id: A0A0B4Y273
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123366:TH3 RS10715
gene id: 1123366:TH3_RS10715
uniprot id: A0A0B4XYF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123366:TH3 RS00920
gene id: 1123366:TH3_RS00920
uniprot id: A0A0B4XVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1123366:TH3 RS15150
gene id: 1123366:TH3_RS15150
uniprot id: A0A0B4Y3C7
names: Similarity
messages: Belongs to the MipA/OmpV family.

1123366:TH3 RS13005
gene id: 1123366:TH3_RS13005
uniprot id: A0A0B4XZP6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123366:TH3 RS12225
gene id: 1123366:TH3_RS12225
uniprot id: A0A0B4XZ97
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1123366:TH3 RS17130
gene id: 1123366:TH3_RS17130
uniprot id: A0A0B4Y235
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS09950
gene id: 1123366:TH3_RS09950
uniprot id: A0A0B4Y0L7
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1123366:TH3 RS03800
gene id: 1123366:TH3_RS03800
uniprot id: A0A0B4XWR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1123366:TH3 RS09095
gene id: 1123366:TH3_RS09095
uniprot id: A0A0B4Y061
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS15615
gene id: 1123366:TH3_RS15615
uniprot id: A0A0B4Y135
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS16565
gene id: 1123366:TH3_RS16565
uniprot id: A0A0B4Y2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1123366:TH3 RS05435
gene id: 1123366:TH3_RS05435
uniprot id: A0A0B4XY09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1123366:TH3 RS18155
gene id: 1123366:TH3_RS18155
uniprot id: A0A0B4Y2K1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1123366:TH3 RS20675
gene id: 1123366:TH3_RS20675
uniprot id: A0A0B4Y6E4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1123366:TH3 RS02660
gene id: 1123366:TH3_RS02660
uniprot id: A0A0B4XWE1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS12630
gene id: 1123366:TH3_RS12630
uniprot id: A0A0B4Y0C2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1123366:TH3 RS01750
gene id: 1123366:TH3_RS01750
uniprot id: A0A0B4XVJ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1123366:TH3 RS12175
gene id: 1123366:TH3_RS12175
uniprot id: A0A0B4XZ87
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS03565
gene id: 1123366:TH3_RS03565
uniprot id: A0A0B4XU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS06185
gene id: 1123366:TH3_RS06185
uniprot id: A0A0B4XVV8
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS10940
gene id: 1123366:TH3_RS10940
uniprot id: A0A0B4Y0T3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1123366:TH3 RS09740
gene id: 1123366:TH3_RS09740
uniprot id: A0A0B4XXY6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123366:TH3 RS06000
gene id: 1123366:TH3_RS06000
uniprot id: A0A0B4XXZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1123366:TH3 RS15175
gene id: 1123366:TH3_RS15175
uniprot id: A0A0B4Y0V3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123366:TH3 RS07845
gene id: 1123366:TH3_RS07845
uniprot id: A0A0B4XZ27
names: Similarity
messages: Belongs to the RelE toxin family.

1123366:TH3 RS16590
gene id: 1123366:TH3_RS16590
uniprot id: A0A0B4XYR7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1123366:TH3 RS04405
gene id: 1123366:TH3_RS04405
uniprot id: A0A0B4XRP4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1123366:TH3 RS05625
gene id: 1123366:TH3_RS05625
uniprot id: A0A0B4XY43
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1123366:TH3 RS08930
gene id: 1123366:TH3_RS08930
uniprot id: A0A0B4XUD6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS10545
gene id: 1123366:TH3_RS10545
uniprot id: A0A0B4Y0W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1123366:TH3 RS09440
gene id: 1123366:TH3_RS09440
uniprot id: A0A0B4XUP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1123366:TH3 RS07880
gene id: 1123366:TH3_RS07880
uniprot id: A0A0B4XXT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS17055
gene id: 1123366:TH3_RS17055
uniprot id: A0A0B4Y4C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1123366:TH3 RS05165
gene id: 1123366:TH3_RS05165
uniprot id: A0A0B4XS23
names: Subcellular Location Annotation
messages: Cytoplasm

1123366:TH3 RS10100
gene id: 1123366:TH3_RS10100
uniprot id: A0A0B4XY51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1123366:TH3 RS11955
gene id: 1123366:TH3_RS11955
uniprot id: A0A0B4Y1M4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1123366:TH3 RS16835
gene id: 1123366:TH3_RS16835
uniprot id: A0A0B4Y473
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1123366:TH3 RS11875
gene id: 1123366:TH3_RS11875
uniprot id: A0A0B4Y1L5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123366:TH3 RS17760
gene id: 1123366:TH3_RS17760
uniprot id: A0A0B4Y2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1123366:TH3 RS12470
gene id: 1123366:TH3_RS12470
uniprot id: A0A0B4Y1Q9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1123366:TH3 RS15385
gene id: 1123366:TH3_RS15385
uniprot id: A0A0B4Y3D0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS18140
gene id: 1123366:TH3_RS18140
uniprot id: A0A0B4Y4T3
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1123366:TH3 RS06200
gene id: 1123366:TH3_RS06200
uniprot id: A0A0B4XSR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1123366:TH3 RS01150
gene id: 1123366:TH3_RS01150
uniprot id: A0A0B4XPT1
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS13905
gene id: 1123366:TH3_RS13905
uniprot id: A0A0B4Y145
names: Similarity
messages: Belongs to the DapA family.

1123366:TH3 RS14000
gene id: 1123366:TH3_RS14000
uniprot id: A0A0B4Y2K7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS15700
gene id: 1123366:TH3_RS15700
uniprot id: A0A0B4Y3H9
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1123366:TH3 RS03600
gene id: 1123366:TH3_RS03600
uniprot id: A0A0B4XWL8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1123366:TH3 RS06855
gene id: 1123366:TH3_RS06855
uniprot id: A0A0B4XX97
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS07210
gene id: 1123366:TH3_RS07210
uniprot id: A0A0B4XZ10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1123366:TH3 RS04215
gene id: 1123366:TH3_RS04215
uniprot id: A0A0B4XUP7
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS20860
gene id: 1123366:TH3_RS20860
uniprot id: A0A0B4Y1C2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS03815
gene id: 1123366:TH3_RS03815
uniprot id: A0A0B4XUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1123366:TH3 RS12940
gene id: 1123366:TH3_RS12940
uniprot id: A0A0B4Y1Z3
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1123366:TH3 RS22550
gene id: 1123366:TH3_RS22550
uniprot id: A0A0B4Y6Z3
names: Similarity
messages: Belongs to the virb1 family.

1123366:TH3 RS17940
gene id: 1123366:TH3_RS17940
uniprot id: A0A0B4Y4T7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1123366:TH3 RS15670
gene id: 1123366:TH3_RS15670
uniprot id: A0A0B4Y3K5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123366:TH3 RS18525
gene id: 1123366:TH3_RS18525
uniprot id: A0A0B4XZZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1123366:TH3 RS17400
gene id: 1123366:TH3_RS17400
uniprot id: A0A0B4XZB9
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS21080
gene id: 1123366:TH3_RS21080
uniprot id: A0A0B4Y1F9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123366:TH3 RS02955
gene id: 1123366:TH3_RS02955
uniprot id: A0A0B4XQU6
names: Similarity
messages: Belongs to the Dps family.

1123366:TH3 RS18585
gene id: 1123366:TH3_RS18585
uniprot id: A0A0B4Y539
names: Similarity
messages: Belongs to the histone deacetylase family.

1123366:TH3 RS00185
gene id: 1123366:TH3_RS00185
uniprot id: A0A0B4XP63
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1123366:TH3 RS20330
gene id: 1123366:TH3_RS20330
uniprot id: A0A0B4Y121
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1123366:TH3 RS01060
gene id: 1123366:TH3_RS01060
uniprot id: A0A0B4XSY7
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS17530
gene id: 1123366:TH3_RS17530
uniprot id: A0A0B4Y2W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1123366:TH3 RS19895
gene id: 1123366:TH3_RS19895
uniprot id: A0A0B4Y5U6
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1123366:TH3 RS01695
gene id: 1123366:TH3_RS01695
uniprot id: A0A0B4XW26
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1123366:TH3 RS10320
gene id: 1123366:TH3_RS10320
uniprot id: A0A0B4XY98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1123366:TH3 RS23440
gene id: 1123366:TH3_RS23440
uniprot id: A0A0B4Y0H7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1123366:TH3 RS21060
gene id: 1123366:TH3_RS21060
uniprot id: A0A0B4Y1F3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1123366:TH3 RS07450
gene id: 1123366:TH3_RS07450
uniprot id: A0A0B4XXK9
names: Subunit
messages: Homodimer.

1123366:TH3 RS12615
gene id: 1123366:TH3_RS12615
uniprot id: A0A0B4Y1W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1123366:TH3 RS21510
gene id: 1123366:TH3_RS21510
uniprot id: A0A0B4Y4N2
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1123366:TH3 RS00715
gene id: 1123366:TH3_RS00715
uniprot id: A0A0B4XPI0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1123366:TH3 RS13970
gene id: 1123366:TH3_RS13970
uniprot id: A0A0B4Y2N5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS07840
gene id: 1123366:TH3_RS07840
uniprot id: A0A0B4XZD2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1123366:TH3 RS19255
gene id: 1123366:TH3_RS19255
uniprot id: A0A0B4Y5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1123366:TH3 RS17865
gene id: 1123366:TH3_RS17865
uniprot id: A0A0B4Y4S9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123366:TH3 RS12580
gene id: 1123366:TH3_RS12580
uniprot id: A0A0B4Y0B2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1123366:TH3 RS12450
gene id: 1123366:TH3_RS12450
uniprot id: A0A0B4XWJ9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1123366:TH3 RS04350
gene id: 1123366:TH3_RS04350
uniprot id: A0A0B4XX56
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS01495
gene id: 1123366:TH3_RS01495
uniprot id: A0A0B4XVY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1123366:TH3 RS10120
gene id: 1123366:TH3_RS10120
uniprot id: A0A0B4XZ28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS09295
gene id: 1123366:TH3_RS09295
uniprot id: A0A0B4XYQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1123366:TH3 RS21160
gene id: 1123366:TH3_RS21160
uniprot id: A0A0B4Y6I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1123366:TH3 RS10585
gene id: 1123366:TH3_RS10585
uniprot id: A0A0B4XZC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1123366:TH3 RS16665
gene id: 1123366:TH3_RS16665
uniprot id: A0A0B4Y440
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS18305
gene id: 1123366:TH3_RS18305
uniprot id: A0A0B4Y3A2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1123366:TH3 RS18985
gene id: 1123366:TH3_RS18985
uniprot id: A0A0B4Y333
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1123366:TH3 RS17925
gene id: 1123366:TH3_RS17925
uniprot id: A0A0B4XZM3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1123366:TH3 RS06140
gene id: 1123366:TH3_RS06140
uniprot id: A0A0B4XYD4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1123366:TH3 RS08985
gene id: 1123366:TH3_RS08985
uniprot id: A0A0B4XYH1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1123366:TH3 RS19490
gene id: 1123366:TH3_RS19490
uniprot id: A0A0B4Y0N2
names: Similarity
messages: Belongs to the RelE toxin family.

1123366:TH3 RS16510
gene id: 1123366:TH3_RS16510
uniprot id: A0A0B4XYQ3
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1123366:TH3 RS13170
gene id: 1123366:TH3_RS13170
uniprot id: A0A0B4XWX2
names: Similarity
messages: Belongs to the GcvT family.

1123366:TH3 RS03225
gene id: 1123366:TH3_RS03225
uniprot id: A0A0B4XQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS10285
gene id: 1123366:TH3_RS10285
uniprot id: A0A0B4XV71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1123366:TH3 RS03750
gene id: 1123366:TH3_RS03750
uniprot id: A0A0B4XWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1123366:TH3 RS03975
gene id: 1123366:TH3_RS03975
uniprot id: A0A0B4XX52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1123366:TH3 RS15815
gene id: 1123366:TH3_RS15815
uniprot id: A0A0B4Y1Y7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1123366:TH3 RS01740
gene id: 1123366:TH3_RS01740
uniprot id: A0A0B4XTD3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1123366:TH3 RS05495
gene id: 1123366:TH3_RS05495
uniprot id: A0A0B4XSA5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1123366:TH3 RS04075
gene id: 1123366:TH3_RS04075
uniprot id: A0A0B4XX70
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1123366:TH3 RS00270
gene id: 1123366:TH3_RS00270
uniprot id: A0A0B4XSK0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1123366:TH3 RS11610
gene id: 1123366:TH3_RS11610
uniprot id: A0A0B4XYX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1123366:TH3 RS15565
gene id: 1123366:TH3_RS15565
uniprot id: A0A0B4Y3G0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1123366:TH3 RS11100
gene id: 1123366:TH3_RS11100
uniprot id: A0A0B4XZK7
names: Subcellular Location Annotation
messages: Cell outer membrane

1123366:TH3 RS12295
gene id: 1123366:TH3_RS12295
uniprot id: A0A0B4XWH1
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1123366:TH3 RS03290
gene id: 1123366:TH3_RS03290
uniprot id: A0A0B4XWS4
names: Subcellular Location Annotation
messages: Cell inner membrane

1123366:TH3 RS17960
gene id: 1123366:TH3_RS17960
uniprot id: A0A0B4Y4U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1123366:TH3 RS02860
gene id: 1123366:TH3_RS02860
uniprot id: A0A0B4XQR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1123366:TH3 RS12045
gene id: 1123366:TH3_RS12045
uniprot id: A0A0B4Y043
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1123366:TH3 RS10420
gene id: 1123366:TH3_RS10420
uniprot id: A0A0B4XYB9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1123366:TH3 RS10095
gene id: 1123366:TH3_RS10095
uniprot id: A0A0B4XZ23
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1123366:TH3 RS07505
gene id: 1123366:TH3_RS07505
uniprot id: A0A0B4XWS5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS14415
gene id: 1123366:TH3_RS14415
uniprot id: A0A0B4Y1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

1123366:TH3 RS12485
gene id: 1123366:TH3_RS12485
uniprot id: A0A0B4XZE3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1123366:TH3 RS07360
gene id: 1123366:TH3_RS07360
uniprot id: A0A0B4XYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS17135
gene id: 1123366:TH3_RS17135
uniprot id: A0A0B4Y4D9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1123366:TH3 RS16575
gene id: 1123366:TH3_RS16575
uniprot id: A0A0B4Y1N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1123366:TH3 RS04560
gene id: 1123366:TH3_RS04560
uniprot id: A0A0B4XW18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1123366:TH3 RS08515
gene id: 1123366:TH3_RS08515
uniprot id: A0A0B4XZT0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS17655
gene id: 1123366:TH3_RS17655
uniprot id: A0A0B4XZG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1123366:TH3 RS15485
gene id: 1123366:TH3_RS15485
uniprot id: A0A0B4Y1U1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS16430
gene id: 1123366:TH3_RS16430
uniprot id: A0A0B4Y3Y7
names: Similarity
messages: Belongs to the Ahb/Nir family.

1123366:TH3 RS10695
gene id: 1123366:TH3_RS10695
uniprot id: A0A0B4Y0Z4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123366:TH3 RS02890
gene id: 1123366:TH3_RS02890
uniprot id: A0A0B4XV86
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS19675
gene id: 1123366:TH3_RS19675
uniprot id: A0A0B4Y3K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1123366:TH3 RS15480
gene id: 1123366:TH3_RS15480
uniprot id: A0A0B4XY79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS12650
gene id: 1123366:TH3_RS12650
uniprot id: A0A0B4XWN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS02655
gene id: 1123366:TH3_RS02655
uniprot id: A0A0B4XTT9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS11135
gene id: 1123366:TH3_RS11135
uniprot id: A0A0B4Y165
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).

1123366:TH3 RS09045
gene id: 1123366:TH3_RS09045
uniprot id: A0A0B4Y047
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1123366:TH3 RS15920
gene id: 1123366:TH3_RS15920
uniprot id: A0A0B4Y191
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1123366:TH3 RS09590
gene id: 1123366:TH3_RS09590
uniprot id: A0A0B4XXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1123366:TH3 RS00190
gene id: 1123366:TH3_RS00190
uniprot id: A0A0B4XTZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1123366:TH3 RS05320
gene id: 1123366:TH3_RS05320
uniprot id: A0A0B4XS58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1123366:TH3 RS00015
gene id: 1123366:TH3_RS00015
uniprot id: A0A0B4XP40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1123366:TH3 RS11570
gene id: 1123366:TH3_RS11570
uniprot id: A0A0B4XVZ1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1123366:TH3 RS20830
gene id: 1123366:TH3_RS20830
uniprot id: A0A0B4Y6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1123366:TH3 RS02270
gene id: 1123366:TH3_RS02270
uniprot id: A0A0B4XUY7
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS07260
gene id: 1123366:TH3_RS07260
uniprot id: A0A0B4XYS8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1123366:TH3 RS03495
gene id: 1123366:TH3_RS03495
uniprot id: A0A0B4XWW5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS17805
gene id: 1123366:TH3_RS17805
uniprot id: A0A0B4Y309
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1123366:TH3 RS06120
gene id: 1123366:TH3_RS06120
uniprot id: A0A0B4XY30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1123366:TH3 RS20190
gene id: 1123366:TH3_RS20190
uniprot id: A0A0B4Y3U4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1123366:TH3 RS18090
gene id: 1123366:TH3_RS18090
uniprot id: A0A0B4Y4S2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS17065
gene id: 1123366:TH3_RS17065
uniprot id: A0A0B4XZ58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1123366:TH3 RS01640
gene id: 1123366:TH3_RS01640
uniprot id: A0A0B4XTB8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1123366:TH3 RS05760
gene id: 1123366:TH3_RS05760
uniprot id: A0A0B4XSG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS10580
gene id: 1123366:TH3_RS10580
uniprot id: A0A0B4XVD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1123366:TH3 RS18835
gene id: 1123366:TH3_RS18835
uniprot id: A0A0B4Y595
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1123366:TH3 RS11260
gene id: 1123366:TH3_RS11260
uniprot id: A0A0B4Y185
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1123366:TH3 RS07180
gene id: 1123366:TH3_RS07180
uniprot id: A0A0B4XWL5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1123366:TH3 RS06065
gene id: 1123366:TH3_RS06065
uniprot id: A0A0B4XYB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1123366:TH3 RS04265
gene id: 1123366:TH3_RS04265
uniprot id: A0A0B4XUQ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS18210
gene id: 1123366:TH3_RS18210
uniprot id: A0A0B4Y4Y4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1123366:TH3 RS09885
gene id: 1123366:TH3_RS09885
uniprot id: A0A0B4XYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1123366:TH3 RS07285
gene id: 1123366:TH3_RS07285
uniprot id: A0A0B4XYT3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS06465
gene id: 1123366:TH3_RS06465
uniprot id: A0A0B4XW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS02375
gene id: 1123366:TH3_RS02375
uniprot id: A0A0B4XTP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS06500
gene id: 1123366:TH3_RS06500
uniprot id: A0A0B4XYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1123366:TH3 RS16490
gene id: 1123366:TH3_RS16490
uniprot id: A0A0B4Y2A0
names: Subcellular Location Annotation
messages: Cytoplasm

1123366:TH3 RS06580
gene id: 1123366:TH3_RS06580
uniprot id: A0A0B4XX16
names: Similarity
messages: Belongs to the GppA/Ppx family.

1123366:TH3 RS17735
gene id: 1123366:TH3_RS17735
uniprot id: A0A0B4Y2C1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS04475
gene id: 1123366:TH3_RS04475
uniprot id: A0A0B4XX76
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1123366:TH3 RS08555
gene id: 1123366:TH3_RS08555
uniprot id: A0A0B4XY85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1123366:TH3 RS17875
gene id: 1123366:TH3_RS17875
uniprot id: A0A0B4XZL3
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS10785
gene id: 1123366:TH3_RS10785
uniprot id: A0A0B4XYG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS16080
gene id: 1123366:TH3_RS16080
uniprot id: A0A0B4XYH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1123366:TH3 RS19965
gene id: 1123366:TH3_RS19965
uniprot id: A0A0B4Y602
names: Similarity
messages: Belongs to the UPF0162 family.

1123366:TH3 RS09050
gene id: 1123366:TH3_RS09050
uniprot id: A0A0B4XZS7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1123366:TH3 RS07060
gene id: 1123366:TH3_RS07060
uniprot id: A0A0B4XYY7
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS20985
gene id: 1123366:TH3_RS20985
uniprot id: A0A0B4Y1E1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1123366:TH3 RS19725
gene id: 1123366:TH3_RS19725
uniprot id: A0A0B4Y484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1123366:TH3 RS08800
gene id: 1123366:TH3_RS08800
uniprot id: A0A0B4XZN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1123366:TH3 RS17265
gene id: 1123366:TH3_RS17265
uniprot id: A0A0B4Y4G5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS19880
gene id: 1123366:TH3_RS19880
uniprot id: A0A0B4Y4A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1123366:TH3 RS03765
gene id: 1123366:TH3_RS03765
uniprot id: A0A0B4XUD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1123366:TH3 RS15405
gene id: 1123366:TH3_RS15405
uniprot id: A0A0B4Y3G5
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1123366:TH3 RS02445
gene id: 1123366:TH3_RS02445
uniprot id: A0A0B4XQI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS17575
gene id: 1123366:TH3_RS17575
uniprot id: A0A0B4XZF3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1123366:TH3 RS08525
gene id: 1123366:TH3_RS08525
uniprot id: A0A0B4XU63
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1123366:TH3 RS06435
gene id: 1123366:TH3_RS06435
uniprot id: A0A0B4XWZ5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS04505
gene id: 1123366:TH3_RS04505
uniprot id: A0A0B4XRQ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS23400
gene id: 1123366:TH3_RS23400
uniprot id: A0A0B4XQP2
names: Subcellular Location Annotation
messages: Secreted

1123366:TH3 RS14410
gene id: 1123366:TH3_RS14410
uniprot id: A0A0B4XXQ6
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS13120
gene id: 1123366:TH3_RS13120
uniprot id: A0A0B4XWW1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1123366:TH3 RS10440
gene id: 1123366:TH3_RS10440
uniprot id: A0A0B4XZA0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS18105
gene id: 1123366:TH3_RS18105
uniprot id: A0A0B4Y2J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1123366:TH3 RS17370
gene id: 1123366:TH3_RS17370
uniprot id: A0A0B4Y4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1123366:TH3 RS03125
gene id: 1123366:TH3_RS03125
uniprot id: A0A0B4XQY0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS12685
gene id: 1123366:TH3_RS12685
uniprot id: A0A0B4Y0D3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS19240
gene id: 1123366:TH3_RS19240
uniprot id: A0A0B4Y3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1123366:TH3 RS06165
gene id: 1123366:TH3_RS06165
uniprot id: A0A0B4XYD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1123366:TH3 RS19885
gene id: 1123366:TH3_RS19885
uniprot id: A0A0B4Y3N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1123366:TH3 RS09430
gene id: 1123366:TH3_RS09430
uniprot id: A0A0B4Y0F0
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS12395
gene id: 1123366:TH3_RS12395
uniprot id: A0A0B4Y1P3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123366:TH3 RS05560
gene id: 1123366:TH3_RS05560
uniprot id: A0A0B4XSB9
names: Similarity
messages: Belongs to the YjdM family.

1123366:TH3 RS01970
gene id: 1123366:TH3_RS01970
uniprot id: A0A0B4XQB2
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS10840
gene id: 1123366:TH3_RS10840
uniprot id: A0A0B4Y0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS17405
gene id: 1123366:TH3_RS17405
uniprot id: A0A0B4Y2U4
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS08100
gene id: 1123366:TH3_RS08100
uniprot id: A0A0B4XZI7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1123366:TH3 RS10020
gene id: 1123366:TH3_RS10020
uniprot id: A0A0B4XY37
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS12595
gene id: 1123366:TH3_RS12595
uniprot id: A0A0B4Y1T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1123366:TH3 RS10700
gene id: 1123366:TH3_RS10700
uniprot id: A0A0B4Y0M3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1123366:TH3 RS18915
gene id: 1123366:TH3_RS18915
uniprot id: A0A0B4Y589
names: Similarity
messages: Belongs to the peptidase M17 family.

1123366:TH3 RS14040
gene id: 1123366:TH3_RS14040
uniprot id: A0A0B4Y099
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS10985
gene id: 1123366:TH3_RS10985
uniprot id: A0A0B4Y136
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS09760
gene id: 1123366:TH3_RS09760
uniprot id: A0A0B4XYX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS17460
gene id: 1123366:TH3_RS17460
uniprot id: A0A0B4Y280
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1123366:TH3 RS19665
gene id: 1123366:TH3_RS19665
uniprot id: A0A0B4Y0R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1123366:TH3 RS19990
gene id: 1123366:TH3_RS19990
uniprot id: A0A0B4Y608
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1123366:TH3 RS17775
gene id: 1123366:TH3_RS17775
uniprot id: A0A0B4XZJ5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1123366:TH3 RS10810
gene id: 1123366:TH3_RS10810
uniprot id: A0A0B4XYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1123366:TH3 RS04640
gene id: 1123366:TH3_RS04640
uniprot id: A0A0B4XUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1123366:TH3 RS11170
gene id: 1123366:TH3_RS11170
uniprot id: A0A0B4XVQ3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1123366:TH3 RS15655
gene id: 1123366:TH3_RS15655
uniprot id: A0A0B4XY97
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1123366:TH3 RS10500
gene id: 1123366:TH3_RS10500
uniprot id: A0A0B4Y0I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1123366:TH3 RS15925
gene id: 1123366:TH3_RS15925
uniprot id: A0A0B4Y3P8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123366:TH3 RS17885
gene id: 1123366:TH3_RS17885
uniprot id: A0A0B4Y2E8
names: Similarity
messages: Belongs to the GST superfamily.

1123366:TH3 RS03485
gene id: 1123366:TH3_RS03485
uniprot id: A0A0B4XVI5
names: Similarity
messages: Belongs to the UPF0145 family.

1123366:TH3 RS11395
gene id: 1123366:TH3_RS11395
uniprot id: A0A0B4XVV5
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS10365
gene id: 1123366:TH3_RS10365
uniprot id: A0A0B4XZ83
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

1123366:TH3 RS04500
gene id: 1123366:TH3_RS04500
uniprot id: A0A0B4XX80
names: Subcellular Location Annotation
messages: Membrane

1123366:TH3 RS02030
gene id: 1123366:TH3_RS02030
uniprot id: A0A0B4XW66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1123366:TH3 RS03840
gene id: 1123366:TH3_RS03840
uniprot id: A0A0B4XUE9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1123366:TH3 RS04155
gene id: 1123366:TH3_RS04155
uniprot id: A0A0B4XX28
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123366:TH3 RS09550
gene id: 1123366:TH3_RS09550
uniprot id: A0A0B4Y000
names: Similarity
messages: Belongs to the HesB/IscA family.

1123366:TH3 RS15100
gene id: 1123366:TH3_RS15100
uniprot id: A0A0B4Y3B8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123366:TH3 RS01540
gene id: 1123366:TH3_RS01540
uniprot id: A0A0B4XT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1123366:TH3 RS14910
gene id: 1123366:TH3_RS14910
uniprot id: A0A0B4XXY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1123366:TH3 RS04090
gene id: 1123366:TH3_RS04090
uniprot id: A0A0B4XVU8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1123366:TH3 RS02910
gene id: 1123366:TH3_RS02910
uniprot id: A0A0B4XQT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1123366:TH3 RS19415
gene id: 1123366:TH3_RS19415
uniprot id: A0A0B4Y3Z9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1123366:TH3 RS17110
gene id: 1123366:TH3_RS17110
uniprot id: A0A0B4Y4D7
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1123366:TH3 RS21010
gene id: 1123366:TH3_RS21010
uniprot id: A0A0B4Y1E5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1123366:TH3 RS06300
gene id: 1123366:TH3_RS06300
uniprot id: A0A0B4XSU1
names: Similarity
messages: Belongs to the acylphosphatase family.

1123366:TH3 RS18825
gene id: 1123366:TH3_RS18825
uniprot id: A0A0B4Y3K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1123366:TH3 RS02120
gene id: 1123366:TH3_RS02120
uniprot id: A0A0B4XUW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123366:TH3 RS15295
gene id: 1123366:TH3_RS15295
uniprot id: A0A0B4Y1R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1123366:TH3 RS09320
gene id: 1123366:TH3_RS09320
uniprot id: A0A0B4XYQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123366:TH3 RS07315
gene id: 1123366:TH3_RS07315
uniprot id: A0A0B4XTG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123366:TH3 RS20720
gene id: 1123366:TH3_RS20720
uniprot id: A0A0B4Y442
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.