1123016:CL52 RS08810
gene id: 1123016:CL52_RS08810
uniprot id: A0A8D3Y0V4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1123016:CL52 RS12255
gene id: 1123016:CL52_RS12255
uniprot id: A0A8D4C6X6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1123016:CL52 RS10980
gene id: 1123016:CL52_RS10980
uniprot id: A0A8D3Y213
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123016:CL52 RS01115
gene id: 1123016:CL52_RS01115
uniprot id: A0A8D3XYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1123016:CL52 RS00990
gene id: 1123016:CL52_RS00990
uniprot id: A0A8D4C4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS06940
gene id: 1123016:CL52_RS06940
uniprot id: A0A8D3Y021
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1123016:CL52 RS02590
gene id: 1123016:CL52_RS02590
uniprot id: A0A8D3XYD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1123016:CL52 RS14995
gene id: 1123016:CL52_RS14995
uniprot id: A0A8D3Y306
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1123016:CL52 RS09770
gene id: 1123016:CL52_RS09770
uniprot id: A0A8D3Y176
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1123016:CL52 RS08535
gene id: 1123016:CL52_RS08535
uniprot id: A0A8D3Y0L4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1123016:CL52 RS19555
gene id: 1123016:CL52_RS19555
uniprot id: A0A8D3Y4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS17305
gene id: 1123016:CL52_RS17305
uniprot id: A0A8D4C484
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1123016:CL52 RS12320
gene id: 1123016:CL52_RS12320
uniprot id: A0A8D3Y1W8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1123016:CL52 RS05835
gene id: 1123016:CL52_RS05835
uniprot id: A0A8D3XZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1123016:CL52 RS17635
gene id: 1123016:CL52_RS17635
uniprot id: A0A8D4C4T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1123016:CL52 RS00765
gene id: 1123016:CL52_RS00765
uniprot id: A0A8D3XXV7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1123016:CL52 RS10040
gene id: 1123016:CL52_RS10040
uniprot id: A0A8D4C6I7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS17720
gene id: 1123016:CL52_RS17720
uniprot id: A0A8D4C361
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1123016:CL52 RS20440
gene id: 1123016:CL52_RS20440
uniprot id: A0A8D3XXW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

1123016:CL52 RS05860
gene id: 1123016:CL52_RS05860
uniprot id: A0A8D4C1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1123016:CL52 RS07675
gene id: 1123016:CL52_RS07675
uniprot id: A0A8D3Y0A8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS00375
gene id: 1123016:CL52_RS00375
uniprot id: A0A8D3XXZ3
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS09000
gene id: 1123016:CL52_RS09000
uniprot id: A0A8D4C6C2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1123016:CL52 RS01575
gene id: 1123016:CL52_RS01575
uniprot id: A0A8D3XY31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1123016:CL52 RS17460
gene id: 1123016:CL52_RS17460
uniprot id: A0A8D3Y3Z1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1123016:CL52 RS11315
gene id: 1123016:CL52_RS11315
uniprot id: A0A8D4C777
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1123016:CL52 RS01525
gene id: 1123016:CL52_RS01525
uniprot id: A0A8D4C4Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1123016:CL52 RS11005
gene id: 1123016:CL52_RS11005
uniprot id: A0A8D4C757
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS17785
gene id: 1123016:CL52_RS17785
uniprot id: A0A8D4C4U8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS17310
gene id: 1123016:CL52_RS17310
uniprot id: A0A8D3Y3X1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1123016:CL52 RS06160
gene id: 1123016:CL52_RS06160
uniprot id: A0A8D4C5U3
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17370
gene id: 1123016:CL52_RS17370
uniprot id: A0A8D4C7X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1123016:CL52 RS10525
gene id: 1123016:CL52_RS10525
uniprot id: A0A8D3Y237
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS01085
gene id: 1123016:CL52_RS01085
uniprot id: A0A8D4C0Y6
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1123016:CL52 RS05470
gene id: 1123016:CL52_RS05470
uniprot id: A0A8D3XZC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1123016:CL52 RS08095
gene id: 1123016:CL52_RS08095
uniprot id: A0A8D3Y0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1123016:CL52 RS04695
gene id: 1123016:CL52_RS04695
uniprot id: A0A8D3XZ47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

1123016:CL52 RS01980
gene id: 1123016:CL52_RS01980
uniprot id: A0A8D4C1A1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1123016:CL52 RS10140
gene id: 1123016:CL52_RS10140
uniprot id: A0A8D3Y1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS10495
gene id: 1123016:CL52_RS10495
uniprot id: A0A8D4C2U4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1123016:CL52 RS02270
gene id: 1123016:CL52_RS02270
uniprot id: A0A8D4C5N5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1123016:CL52 RS05650
gene id: 1123016:CL52_RS05650
uniprot id: A0A8D3Y008
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS15825
gene id: 1123016:CL52_RS15825
uniprot id: A0A8D3Y3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS11715
gene id: 1123016:CL52_RS11715
uniprot id: A0A8D3Y243
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1123016:CL52 RS10645
gene id: 1123016:CL52_RS10645
uniprot id: A0A8D4C2V4
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS06225
gene id: 1123016:CL52_RS06225
uniprot id: A0A8D3Y5K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1123016:CL52 RS05055
gene id: 1123016:CL52_RS05055
uniprot id: A0A8D4C649
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1123016:CL52 RS12745
gene id: 1123016:CL52_RS12745
uniprot id: A0A8D3Y2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1123016:CL52 RS21650
gene id: 1123016:CL52_RS21650
uniprot id: A0A8D3Y4Y6
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1123016:CL52 RS12485
gene id: 1123016:CL52_RS12485
uniprot id: A0A8D4C375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1123016:CL52 RS11230
gene id: 1123016:CL52_RS11230
uniprot id: A0A8D3Y1I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1123016:CL52 RS03665
gene id: 1123016:CL52_RS03665
uniprot id: A0A8D4C5C9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1123016:CL52 RS18230
gene id: 1123016:CL52_RS18230
uniprot id: A0A8D3Y453
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1123016:CL52 RS09255
gene id: 1123016:CL52_RS09255
uniprot id: A0A8D3Y0Y1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1123016:CL52 RS19475
gene id: 1123016:CL52_RS19475
uniprot id: A0A8D3Y4J7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS08645
gene id: 1123016:CL52_RS08645
uniprot id: A0A8D3Y0T5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1123016:CL52 RS13655
gene id: 1123016:CL52_RS13655
uniprot id: A0A8D4C7M2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS05195
gene id: 1123016:CL52_RS05195
uniprot id: A0A8D3XZ99
names: Similarity
messages: Belongs to the UPF0234 family.

1123016:CL52 RS01005
gene id: 1123016:CL52_RS01005
uniprot id: A0A8D3XY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS17200
gene id: 1123016:CL52_RS17200
uniprot id: A0A8D3Y3X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1123016:CL52 RS10590
gene id: 1123016:CL52_RS10590
uniprot id: A0A8D3Y1Q2
names: Similarity
messages: Belongs to the PrpD family.

1123016:CL52 RS15685
gene id: 1123016:CL52_RS15685
uniprot id: A0A8D3Y3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1123016:CL52 RS16595
gene id: 1123016:CL52_RS16595
uniprot id: A0A8D3Y3P7
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1123016:CL52 RS17215
gene id: 1123016:CL52_RS17215
uniprot id: A0A8D4C330
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1123016:CL52 RS17900
gene id: 1123016:CL52_RS17900
uniprot id: A0A8D3Y444
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1123016:CL52 RS03645
gene id: 1123016:CL52_RS03645
uniprot id: A0A8D3XZ06
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS03320
gene id: 1123016:CL52_RS03320
uniprot id: A0A8D4C1K2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123016:CL52 RS07150
gene id: 1123016:CL52_RS07150
uniprot id: A0A8D3Y082
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1123016:CL52 RS11485
gene id: 1123016:CL52_RS11485
uniprot id: A0A8D3Y1T5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS02765
gene id: 1123016:CL52_RS02765
uniprot id: A0A8D4C1A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

1123016:CL52 RS04585
gene id: 1123016:CL52_RS04585
uniprot id: A0A8D4C5J0
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1123016:CL52 RS10015
gene id: 1123016:CL52_RS10015
uniprot id: A0A8D3Y1A5
names: Similarity
messages: Belongs to the DsrF/TusC family.

1123016:CL52 RS02255
gene id: 1123016:CL52_RS02255
uniprot id: A0A8D3XZ08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1123016:CL52 RS05375
gene id: 1123016:CL52_RS05375
uniprot id: A0A8D4C220
names: Similarity
messages: Belongs to the hyi family.

1123016:CL52 RS01100
gene id: 1123016:CL52_RS01100
uniprot id: A0A8D3XY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1123016:CL52 RS17055
gene id: 1123016:CL52_RS17055
uniprot id: A0A8D4C4P5
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1123016:CL52 RS15200
gene id: 1123016:CL52_RS15200
uniprot id: A0A8D3Y2Z6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1123016:CL52 RS12550
gene id: 1123016:CL52_RS12550
uniprot id: A0A8D4C6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1123016:CL52 RS00660
gene id: 1123016:CL52_RS00660
uniprot id: A0A8D3XXM9
names: Similarity
messages: Belongs to the creatininase superfamily.

1123016:CL52 RS18055
gene id: 1123016:CL52_RS18055
uniprot id: A0A8D3Y489
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1123016:CL52 RS09320
gene id: 1123016:CL52_RS09320
uniprot id: A0A8D3Y0Z4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1123016:CL52 RS01260
gene id: 1123016:CL52_RS01260
uniprot id: A0A8D3XXV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1123016:CL52 RS14845
gene id: 1123016:CL52_RS14845
uniprot id: A0A8D3Y2Y5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1123016:CL52 RS19535
gene id: 1123016:CL52_RS19535
uniprot id: A0A8D3Y4H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1123016:CL52 RS04450
gene id: 1123016:CL52_RS04450
uniprot id: A0A8D3XZ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1123016:CL52 RS09370
gene id: 1123016:CL52_RS09370
uniprot id: A0A8D3Y125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1123016:CL52 RS03295
gene id: 1123016:CL52_RS03295
uniprot id: A0A8D3XYL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123016:CL52 RS10610
gene id: 1123016:CL52_RS10610
uniprot id: A0A8D3Y1G9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS03655
gene id: 1123016:CL52_RS03655
uniprot id: A0A8D3XYR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1123016:CL52 RS17580
gene id: 1123016:CL52_RS17580
uniprot id: A0A8D3Y3T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1123016:CL52 RS16855
gene id: 1123016:CL52_RS16855
uniprot id: A0A8D3Y3R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS08290
gene id: 1123016:CL52_RS08290
uniprot id: A0A8D3Y0M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1123016:CL52 RS15930
gene id: 1123016:CL52_RS15930
uniprot id: A0A8D3Y3D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

1123016:CL52 RS09740
gene id: 1123016:CL52_RS09740
uniprot id: A0A8D3Y1L3
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17555
gene id: 1123016:CL52_RS17555
uniprot id: A0A8D4C4T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1123016:CL52 RS10330
gene id: 1123016:CL52_RS10330
uniprot id: A0A8D3Y1C0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS17280
gene id: 1123016:CL52_RS17280
uniprot id: A0A8D4C4R3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1123016:CL52 RS11645
gene id: 1123016:CL52_RS11645
uniprot id: A0A8D3Y2H7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS15005
gene id: 1123016:CL52_RS15005
uniprot id: A0A8D3Y2V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS18935
gene id: 1123016:CL52_RS18935
uniprot id: A0A8D4C3F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1123016:CL52 RS14315
gene id: 1123016:CL52_RS14315
uniprot id: A0A8D4C7B0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123016:CL52 RS02075
gene id: 1123016:CL52_RS02075
uniprot id: A0A8D3XY65
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1123016:CL52 RS10810
gene id: 1123016:CL52_RS10810
uniprot id: A0A8D4C2W5
names: Similarity
messages: Belongs to the peptidase S49 family.

1123016:CL52 RS05910
gene id: 1123016:CL52_RS05910
uniprot id: A0A8D4C258
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1123016:CL52 RS06420
gene id: 1123016:CL52_RS06420
uniprot id: A0A8D3XZY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1123016:CL52 RS18315
gene id: 1123016:CL52_RS18315
uniprot id: A0A8D4C4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1123016:CL52 RS05810
gene id: 1123016:CL52_RS05810
uniprot id: A0A8D3Y0E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1123016:CL52 RS12355
gene id: 1123016:CL52_RS12355
uniprot id: A0A8D3Y2C3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1123016:CL52 RS03965
gene id: 1123016:CL52_RS03965
uniprot id: A0A8D4C5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS16985
gene id: 1123016:CL52_RS16985
uniprot id: A0A8D4C313
names: Similarity
messages: Belongs to the YjdM family.

1123016:CL52 RS04490
gene id: 1123016:CL52_RS04490
uniprot id: A0A8D3XZ37
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1123016:CL52 RS13605
gene id: 1123016:CL52_RS13605
uniprot id: A0A8D4C2B9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1123016:CL52 RS17435
gene id: 1123016:CL52_RS17435
uniprot id: A0A8D3Y3Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1123016:CL52 RS13840
gene id: 1123016:CL52_RS13840
uniprot id: A0A8D4C2D6
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS05250
gene id: 1123016:CL52_RS05250
uniprot id: A0A8D3XZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS13400
gene id: 1123016:CL52_RS13400
uniprot id: A0A8D3Y352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1123016:CL52 RS05815
gene id: 1123016:CL52_RS05815
uniprot id: A0A8D4C694
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1123016:CL52 RS20065
gene id: 1123016:CL52_RS20065
uniprot id: A0A8D3Y4W5
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

1123016:CL52 RS02950
gene id: 1123016:CL52_RS02950
uniprot id: A0A8D3XYP9
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1123016:CL52 RS02295
gene id: 1123016:CL52_RS02295
uniprot id: A0A8D4C037
names: Similarity
messages: Belongs to the UPF0047 family.

1123016:CL52 RS16040
gene id: 1123016:CL52_RS16040
uniprot id: A0A8D4C3Z4
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS13175
gene id: 1123016:CL52_RS13175
uniprot id: A0A8D4C737
names: Similarity
messages: Belongs to the GSP E family.

1123016:CL52 RS04395
gene id: 1123016:CL52_RS04395
uniprot id: A0A8D3XZ81
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1123016:CL52 RS09565
gene id: 1123016:CL52_RS09565
uniprot id: A0A8D3Y121
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS03210
gene id: 1123016:CL52_RS03210
uniprot id: A0A8D3XZ98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1123016:CL52 RS11455
gene id: 1123016:CL52_RS11455
uniprot id: A0A8D3Y272
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1123016:CL52 RS08455
gene id: 1123016:CL52_RS08455
uniprot id: A0A8D3Y113
names: Similarity
messages: Belongs to the citrate synthase family.

1123016:CL52 RS15500
gene id: 1123016:CL52_RS15500
uniprot id: A0A8D3Y338
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1123016:CL52 RS08415
gene id: 1123016:CL52_RS08415
uniprot id: A0A8D3Y0K7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1123016:CL52 RS02190
gene id: 1123016:CL52_RS02190
uniprot id: A0A8D4C5N0
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1123016:CL52 RS08385
gene id: 1123016:CL52_RS08385
uniprot id: A0A8D3Y0J1
names: Similarity
messages: Belongs to the YkuD family.

1123016:CL52 RS01250
gene id: 1123016:CL52_RS01250
uniprot id: A0A8D3XY26
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1123016:CL52 RS19490
gene id: 1123016:CL52_RS19490
uniprot id: A0A8D3Y4F9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS08695
gene id: 1123016:CL52_RS08695
uniprot id: A0A8D3Y173
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1123016:CL52 RS11900
gene id: 1123016:CL52_RS11900
uniprot id: A0A8D3Y1R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1123016:CL52 RS11265
gene id: 1123016:CL52_RS11265
uniprot id: A0A8D4C1V8
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS16885
gene id: 1123016:CL52_RS16885
uniprot id: A0A8D4C879
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1123016:CL52 RS01985
gene id: 1123016:CL52_RS01985
uniprot id: A0A8D3XY55
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1123016:CL52 RS10390
gene id: 1123016:CL52_RS10390
uniprot id: A0A8D3Y1E9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1123016:CL52 RS00435
gene id: 1123016:CL52_RS00435
uniprot id: A0A8D3XXJ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1123016:CL52 RS18855
gene id: 1123016:CL52_RS18855
uniprot id: A0A8D3Y479
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1123016:CL52 RS12645
gene id: 1123016:CL52_RS12645
uniprot id: A0A8D3Y253
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1123016:CL52 RS12810
gene id: 1123016:CL52_RS12810
uniprot id: A0A8D3Y281
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS19500
gene id: 1123016:CL52_RS19500
uniprot id: A0A8D4C8A6
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1123016:CL52 RS08465
gene id: 1123016:CL52_RS08465
uniprot id: A0A8D3Y1E5
names: Similarity
messages: Belongs to the PrpF family.

1123016:CL52 RS14210
gene id: 1123016:CL52_RS14210
uniprot id: A0A8D4C3Y6
names: Similarity
messages: Belongs to the hyi family.

1123016:CL52 RS05280
gene id: 1123016:CL52_RS05280
uniprot id: A0A8D4C662
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS00570
gene id: 1123016:CL52_RS00570
uniprot id: A0A8D3XXL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1123016:CL52 RS04850
gene id: 1123016:CL52_RS04850
uniprot id: A0A8D4C1Q8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1123016:CL52 RS11705
gene id: 1123016:CL52_RS11705
uniprot id: A0A8D3Y1T8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1123016:CL52 RS09815
gene id: 1123016:CL52_RS09815
uniprot id: A0A8D3Y1M1
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS07460
gene id: 1123016:CL52_RS07460
uniprot id: A0A8D3Y0C2
names: Similarity
messages: Belongs to the Gfa family.

1123016:CL52 RS12235
gene id: 1123016:CL52_RS12235
uniprot id: A0A8D3Y234
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1123016:CL52 RS03195
gene id: 1123016:CL52_RS03195
uniprot id: A0A8D3XYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1123016:CL52 RS10065
gene id: 1123016:CL52_RS10065
uniprot id: A0A8D3Y180
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1123016:CL52 RS04965
gene id: 1123016:CL52_RS04965
uniprot id: A0A8D4C645
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1123016:CL52 RS17255
gene id: 1123016:CL52_RS17255
uniprot id: A0A8D3Y3N4
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1123016:CL52 RS05240
gene id: 1123016:CL52_RS05240
uniprot id: A0A8D3XZ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1123016:CL52 RS11190
gene id: 1123016:CL52_RS11190
uniprot id: A0A8D4C1V3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1123016:CL52 RS02415
gene id: 1123016:CL52_RS02415
uniprot id: A0A8D3XYR1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1123016:CL52 RS12875
gene id: 1123016:CL52_RS12875
uniprot id: A0A8D3Y283
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1123016:CL52 RS00575
gene id: 1123016:CL52_RS00575
uniprot id: A0A8D4BZS0
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1123016:CL52 RS05450
gene id: 1123016:CL52_RS05450
uniprot id: A0A8D4C225
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

1123016:CL52 RS13610
gene id: 1123016:CL52_RS13610
uniprot id: A0A8D4C761
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1123016:CL52 RS05735
gene id: 1123016:CL52_RS05735
uniprot id: A0A8D3Y0C4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1123016:CL52 RS03100
gene id: 1123016:CL52_RS03100
uniprot id: A0A8D4C084
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123016:CL52 RS05895
gene id: 1123016:CL52_RS05895
uniprot id: A0A8D4C698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS05430
gene id: 1123016:CL52_RS05430
uniprot id: A0A8D3Y089
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1123016:CL52 RS10865
gene id: 1123016:CL52_RS10865
uniprot id: A0A8D3Y1E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1123016:CL52 RS20020
gene id: 1123016:CL52_RS20020
uniprot id: A0A8D4C8S9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1123016:CL52 RS15555
gene id: 1123016:CL52_RS15555
uniprot id: A0A8D4C491
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1123016:CL52 RS17025
gene id: 1123016:CL52_RS17025
uniprot id: A0A8D3Y3K5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1123016:CL52 RS05025
gene id: 1123016:CL52_RS05025
uniprot id: A0A8D3XZE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1123016:CL52 RS18770
gene id: 1123016:CL52_RS18770
uniprot id: A0A8D3Y4J4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1123016:CL52 RS16610
gene id: 1123016:CL52_RS16610
uniprot id: A0A8D4C2Y3
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1123016:CL52 RS01245
gene id: 1123016:CL52_RS01245
uniprot id: A0A8D3XYB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1123016:CL52 RS11815
gene id: 1123016:CL52_RS11815
uniprot id: A0A8D3Y1Y5
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

1123016:CL52 RS12150
gene id: 1123016:CL52_RS12150
uniprot id: A0A8D4C7D1
names: Similarity
messages: Belongs to the type III secretion exporter family.

1123016:CL52 RS11345
gene id: 1123016:CL52_RS11345
uniprot id: A0A8D4C6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS16890
gene id: 1123016:CL52_RS16890
uniprot id: A0A8D3Y3P2
names: Similarity
messages: Belongs to the FPG family.

1123016:CL52 RS11925
gene id: 1123016:CL52_RS11925
uniprot id: A0A8D4C3G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS17825
gene id: 1123016:CL52_RS17825
uniprot id: A0A8D3Y433
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS00920
gene id: 1123016:CL52_RS00920
uniprot id: A0A8D3XXR0
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17550
gene id: 1123016:CL52_RS17550
uniprot id: A0A8D3Y414
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1123016:CL52 RS19690
gene id: 1123016:CL52_RS19690
uniprot id: A0A8D3Y4K2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1123016:CL52 RS19780
gene id: 1123016:CL52_RS19780
uniprot id: A0A8D3Y4N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1123016:CL52 RS11745
gene id: 1123016:CL52_RS11745
uniprot id: A0A8D4C3E8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.
messages: Periplasm

1123016:CL52 RS08900
gene id: 1123016:CL52_RS08900
uniprot id: A0A8D3Y0U6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1123016:CL52 RS10045
gene id: 1123016:CL52_RS10045
uniprot id: A0A8D3Y166
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1123016:CL52 RS02280
gene id: 1123016:CL52_RS02280
uniprot id: A0A8D3XYH2
names: Similarity
messages: Belongs to the P(II) protein family.

1123016:CL52 RS05175
gene id: 1123016:CL52_RS05175
uniprot id: A0A8D3XZL7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1123016:CL52 RS09325
gene id: 1123016:CL52_RS09325
uniprot id: A0A8D3Y1G1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS10020
gene id: 1123016:CL52_RS10020
uniprot id: A0A8D4C321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1123016:CL52 RS12800
gene id: 1123016:CL52_RS12800
uniprot id: A0A8D3Y273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS07130
gene id: 1123016:CL52_RS07130
uniprot id: A0A8D3Y0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1123016:CL52 RS01605
gene id: 1123016:CL52_RS01605
uniprot id: A0A8D3XY12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1123016:CL52 RS19105
gene id: 1123016:CL52_RS19105
uniprot id: A0A8D4C881
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1123016:CL52 RS04170
gene id: 1123016:CL52_RS04170
uniprot id: A0A8D3XZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1123016:CL52 RS02000
gene id: 1123016:CL52_RS02000
uniprot id: A0A8D3XY57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS04155
gene id: 1123016:CL52_RS04155
uniprot id: A0A8D3XZV2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1123016:CL52 RS17020
gene id: 1123016:CL52_RS17020
uniprot id: A0A8D3Y3X4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1123016:CL52 RS16590
gene id: 1123016:CL52_RS16590
uniprot id: A0A8D3Y3K3
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1123016:CL52 RS05490
gene id: 1123016:CL52_RS05490
uniprot id: A0A8D3XZM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1123016:CL52 RS15985
gene id: 1123016:CL52_RS15985
uniprot id: A0A8D3Y3K4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1123016:CL52 RS05655
gene id: 1123016:CL52_RS05655
uniprot id: A0A8D3XZG1
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS10555
gene id: 1123016:CL52_RS10555
uniprot id: A0A8D4C1R0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1123016:CL52 RS01920
gene id: 1123016:CL52_RS01920
uniprot id: A0A8D4C518
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1123016:CL52 RS15020
gene id: 1123016:CL52_RS15020
uniprot id: A0A8D3Y309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1123016:CL52 RS01155
gene id: 1123016:CL52_RS01155
uniprot id: A0A8D3XXU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1123016:CL52 RS00195
gene id: 1123016:CL52_RS00195
uniprot id: A0A8D4C4N6
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS08060
gene id: 1123016:CL52_RS08060
uniprot id: A0A8D3Y0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1123016:CL52 RS14970
gene id: 1123016:CL52_RS14970
uniprot id: A0A8D4C7F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1123016:CL52 RS07125
gene id: 1123016:CL52_RS07125
uniprot id: A0A8D3Y076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1123016:CL52 RS01615
gene id: 1123016:CL52_RS01615
uniprot id: A0A8D3XYG7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1123016:CL52 RS11940
gene id: 1123016:CL52_RS11940
uniprot id: A0A8D4C6V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1123016:CL52 RS08995
gene id: 1123016:CL52_RS08995
uniprot id: A0A8D4C1E0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1123016:CL52 RS01555
gene id: 1123016:CL52_RS01555
uniprot id: A0A8D3XYR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1123016:CL52 RS02580
gene id: 1123016:CL52_RS02580
uniprot id: A0A8D3XYK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS11185
gene id: 1123016:CL52_RS11185
uniprot id: A0A8D3Y1H7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1123016:CL52 RS14975
gene id: 1123016:CL52_RS14975
uniprot id: A0A8D3Y2V9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS01755
gene id: 1123016:CL52_RS01755
uniprot id: A0A8D3XY21
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS09305
gene id: 1123016:CL52_RS09305
uniprot id: A0A8D4C6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

1123016:CL52 RS12805
gene id: 1123016:CL52_RS12805
uniprot id: A0A8D3Y2N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS19410
gene id: 1123016:CL52_RS19410
uniprot id: A0A8D4C572
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS15630
gene id: 1123016:CL52_RS15630
uniprot id: A0A8D4C498
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS06740
gene id: 1123016:CL52_RS06740
uniprot id: A0A8D3Y061
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1123016:CL52 RS05275
gene id: 1123016:CL52_RS05275
uniprot id: A0A8D3Y071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1123016:CL52 RS07910
gene id: 1123016:CL52_RS07910
uniprot id: A0A8D3Y0X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1123016:CL52 RS13270
gene id: 1123016:CL52_RS13270
uniprot id: A0A8D4C742
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1123016:CL52 RS09110
gene id: 1123016:CL52_RS09110
uniprot id: A0A8D3Y0T7
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1123016:CL52 RS02990
gene id: 1123016:CL52_RS02990
uniprot id: A0A8D3XYI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1123016:CL52 RS09520
gene id: 1123016:CL52_RS09520
uniprot id: A0A8D4C6X7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS08735
gene id: 1123016:CL52_RS08735
uniprot id: A0A8D4C2T3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1123016:CL52 RS04770
gene id: 1123016:CL52_RS04770
uniprot id: A0A8D4C1Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1123016:CL52 RS12220
gene id: 1123016:CL52_RS12220
uniprot id: A0A8D3Y2Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1123016:CL52 RS04675
gene id: 1123016:CL52_RS04675
uniprot id: A0A8D3XZF5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1123016:CL52 RS04900
gene id: 1123016:CL52_RS04900
uniprot id: A0A8D4C1Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1123016:CL52 RS15820
gene id: 1123016:CL52_RS15820
uniprot id: A0A8D3Y3V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1123016:CL52 RS04385
gene id: 1123016:CL52_RS04385
uniprot id: A0A8D4C613
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS03515
gene id: 1123016:CL52_RS03515
uniprot id: A0A8D4C5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS18825
gene id: 1123016:CL52_RS18825
uniprot id: A0A8D3Y483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1123016:CL52 RS20215
gene id: 1123016:CL52_RS20215
uniprot id: A0A8D4C3P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1123016:CL52 RS20240
gene id: 1123016:CL52_RS20240
uniprot id: A0A8D3Y5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1123016:CL52 RS18560
gene id: 1123016:CL52_RS18560
uniprot id: A0A8D4C3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS12690
gene id: 1123016:CL52_RS12690
uniprot id: A0A8D4C3M0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1123016:CL52 RS08235
gene id: 1123016:CL52_RS08235
uniprot id: A0A8D3Y0G6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS06745
gene id: 1123016:CL52_RS06745
uniprot id: A0A8D3Y0E9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1123016:CL52 RS17415
gene id: 1123016:CL52_RS17415
uniprot id: A0A8D4C8B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1123016:CL52 RS05090
gene id: 1123016:CL52_RS05090
uniprot id: A0A8D3XZ66
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1123016:CL52 RS00720
gene id: 1123016:CL52_RS00720
uniprot id: A0A8D3XXW1
names: Similarity
messages: Belongs to the CFA/CMAS family.

1123016:CL52 RS04610
gene id: 1123016:CL52_RS04610
uniprot id: A0A8D3XZ97
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1123016:CL52 RS07680
gene id: 1123016:CL52_RS07680
uniprot id: A0A8D3Y144
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1123016:CL52 RS18045
gene id: 1123016:CL52_RS18045
uniprot id: A0A8D3Y4Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1123016:CL52 RS11495
gene id: 1123016:CL52_RS11495
uniprot id: A0A8D4C3C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1123016:CL52 RS03630
gene id: 1123016:CL52_RS03630
uniprot id: A0A8D3XZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS15870
gene id: 1123016:CL52_RS15870
uniprot id: A0A8D3Y378
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1123016:CL52 RS11730
gene id: 1123016:CL52_RS11730
uniprot id: A0A8D4C7A5
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS10145
gene id: 1123016:CL52_RS10145
uniprot id: A0A8D3Y196
names: Cofactor
messages: Can also use Mn(2+) ion.

1123016:CL52 RS06095
gene id: 1123016:CL52_RS06095
uniprot id: A0A8D3Y045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1123016:CL52 RS07225
gene id: 1123016:CL52_RS07225
uniprot id: A0A8D4C6I4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1123016:CL52 RS11435
gene id: 1123016:CL52_RS11435
uniprot id: A0A8D4C6S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1123016:CL52 RS19785
gene id: 1123016:CL52_RS19785
uniprot id: A0A8D3Y4X7
names: Similarity
messages: Belongs to the VgrG protein family.

1123016:CL52 RS02400
gene id: 1123016:CL52_RS02400
uniprot id: A0A8D3XYB4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1123016:CL52 RS05875
gene id: 1123016:CL52_RS05875
uniprot id: A0A8D3XZS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1123016:CL52 RS08510
gene id: 1123016:CL52_RS08510
uniprot id: A0A8D4C2H3
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1123016:CL52 RS10640
gene id: 1123016:CL52_RS10640
uniprot id: A0A8D3Y1C7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS18620
gene id: 1123016:CL52_RS18620
uniprot id: A0A8D3Y4H3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1123016:CL52 RS11950
gene id: 1123016:CL52_RS11950
uniprot id: A0A8D4C337
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS05985
gene id: 1123016:CL52_RS05985
uniprot id: A0A8D4C262
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1123016:CL52 RS18875
gene id: 1123016:CL52_RS18875
uniprot id: A0A8D4C4P3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1123016:CL52 RS06870
gene id: 1123016:CL52_RS06870
uniprot id: A0A8D4C101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1123016:CL52 RS08330
gene id: 1123016:CL52_RS08330
uniprot id: A0A8D3Y0N6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1123016:CL52 RS07660
gene id: 1123016:CL52_RS07660
uniprot id: A0A8D3Y0T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS06200
gene id: 1123016:CL52_RS06200
uniprot id: A0A8D3Y0K3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123016:CL52 RS16620
gene id: 1123016:CL52_RS16620
uniprot id: A0A8D3Y3H6
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1123016:CL52 RS09530
gene id: 1123016:CL52_RS09530
uniprot id: A0A8D3Y148
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS03790
gene id: 1123016:CL52_RS03790
uniprot id: A0A8D3XYX3
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1123016:CL52 RS00020
gene id: 1123016:CL52_RS00020
uniprot id: A0A8D3XXD3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1123016:CL52 RS01010
gene id: 1123016:CL52_RS01010
uniprot id: A0A8D3XY83
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS07690
gene id: 1123016:CL52_RS07690
uniprot id: A0A8D3Y0F2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1123016:CL52 RS12455
gene id: 1123016:CL52_RS12455
uniprot id: A0A8D3Y263
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS02740
gene id: 1123016:CL52_RS02740
uniprot id: A0A8D4C1F9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1123016:CL52 RS17135
gene id: 1123016:CL52_RS17135
uniprot id: A0A8D3Y3L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1123016:CL52 RS04420
gene id: 1123016:CL52_RS04420
uniprot id: A0A8D4C0I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1123016:CL52 RS01645
gene id: 1123016:CL52_RS01645
uniprot id: A0A8D4C5J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS01550
gene id: 1123016:CL52_RS01550
uniprot id: A0A8D3XY71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1123016:CL52 RS05150
gene id: 1123016:CL52_RS05150
uniprot id: A0A8D3XZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1123016:CL52 RS20250
gene id: 1123016:CL52_RS20250
uniprot id: A0A8D3Y506
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1123016:CL52 RS14925
gene id: 1123016:CL52_RS14925
uniprot id: A0A8D3Y375
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS09155
gene id: 1123016:CL52_RS09155
uniprot id: A0A8D3Y0T4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1123016:CL52 RS08970
gene id: 1123016:CL52_RS08970
uniprot id: A0A8D4C6U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

1123016:CL52 RS06375
gene id: 1123016:CL52_RS06375
uniprot id: A0A8D4C298
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1123016:CL52 RS12230
gene id: 1123016:CL52_RS12230
uniprot id: A0A8D3Y222
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1123016:CL52 RS03530
gene id: 1123016:CL52_RS03530
uniprot id: A0A8D3XZ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1123016:CL52 RS08480
gene id: 1123016:CL52_RS08480
uniprot id: A0A8D3Y0R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1123016:CL52 RS14770
gene id: 1123016:CL52_RS14770
uniprot id: A0A8D3Y2X5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1123016:CL52 RS16410
gene id: 1123016:CL52_RS16410
uniprot id: A0A8D3Y5M8
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS06910
gene id: 1123016:CL52_RS06910
uniprot id: A0A8D3XZZ3
names: Similarity
messages: Belongs to the asparagine synthetase family.

1123016:CL52 RS12125
gene id: 1123016:CL52_RS12125
uniprot id: A0A8D3Y2F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1123016:CL52 RS16080
gene id: 1123016:CL52_RS16080
uniprot id: A0A8D3Y3E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1123016:CL52 RS07140
gene id: 1123016:CL52_RS07140
uniprot id: A0A8D3Y0X5
names: Similarity
messages: Belongs to the UPF0434 family.

1123016:CL52 RS02745
gene id: 1123016:CL52_RS02745
uniprot id: A0A8D3XYF9
names: Function
names: Miscellaneous
names: Similarity
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.

1123016:CL52 RS15485
gene id: 1123016:CL52_RS15485
uniprot id: A0A8D3Y320
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1123016:CL52 RS06025
gene id: 1123016:CL52_RS06025
uniprot id: A0A8D3XZU3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1123016:CL52 RS08825
gene id: 1123016:CL52_RS08825
uniprot id: A0A8D4C1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1123016:CL52 RS10005
gene id: 1123016:CL52_RS10005
uniprot id: A0A8D4C704
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1123016:CL52 RS12665
gene id: 1123016:CL52_RS12665
uniprot id: A0A8D3Y219
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1123016:CL52 RS04320
gene id: 1123016:CL52_RS04320
uniprot id: A0A8D3XZ72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1123016:CL52 RS16265
gene id: 1123016:CL52_RS16265
uniprot id: A0A8D4C7P6
names: Similarity
messages: Belongs to the peptidase S14 family.

1123016:CL52 RS03930
gene id: 1123016:CL52_RS03930
uniprot id: A0A8D3XZR9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1123016:CL52 RS17270
gene id: 1123016:CL52_RS17270
uniprot id: A0A8D3Y3T6
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

1123016:CL52 RS20140
gene id: 1123016:CL52_RS20140
uniprot id: A0A8D4C4Y0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1123016:CL52 RS12260
gene id: 1123016:CL52_RS12260
uniprot id: A0A8D3Y1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1123016:CL52 RS19095
gene id: 1123016:CL52_RS19095
uniprot id: A0A8D3Y4A6
names: Similarity
messages: Belongs to the HSP15 family.

1123016:CL52 RS04000
gene id: 1123016:CL52_RS04000
uniprot id: A0A8D3XYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS17655
gene id: 1123016:CL52_RS17655
uniprot id: A0A8D3Y3U3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1123016:CL52 RS04405
gene id: 1123016:CL52_RS04405
uniprot id: A0A8D3XZ23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1123016:CL52 RS01080
gene id: 1123016:CL52_RS01080
uniprot id: A0A8D3XXT2
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1123016:CL52 RS17230
gene id: 1123016:CL52_RS17230
uniprot id: A0A8D4C477
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1123016:CL52 RS15635
gene id: 1123016:CL52_RS15635
uniprot id: A0A8D3Y341
names: Similarity
messages: Belongs to the LOG family.

1123016:CL52 RS07375
gene id: 1123016:CL52_RS07375
uniprot id: A0A8D3Y105
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS19565
gene id: 1123016:CL52_RS19565
uniprot id: A0A8D3Y4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1123016:CL52 RS02955
gene id: 1123016:CL52_RS02955
uniprot id: A0A8D3XZ77
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1123016:CL52 RS06635
gene id: 1123016:CL52_RS06635
uniprot id: A0A8D4C229
names: Similarity
messages: Belongs to the aspartokinase family.

1123016:CL52 RS03255
gene id: 1123016:CL52_RS03255
uniprot id: A0A8D4C097
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1123016:CL52 RS03220
gene id: 1123016:CL52_RS03220
uniprot id: A0A8D3XZJ2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1123016:CL52 RS06735
gene id: 1123016:CL52_RS06735
uniprot id: A0A8D4C235
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1123016:CL52 RS14480
gene id: 1123016:CL52_RS14480
uniprot id: A0A8D4C2I5
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1123016:CL52 RS01960
gene id: 1123016:CL52_RS01960
uniprot id: A0A8D3XZ46
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1123016:CL52 RS07510
gene id: 1123016:CL52_RS07510
uniprot id: A0A8D3Y0R1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1123016:CL52 RS12315
gene id: 1123016:CL52_RS12315
uniprot id: A0A8D4C3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1123016:CL52 RS06605
gene id: 1123016:CL52_RS06605
uniprot id: A0A8D3Y023
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1123016:CL52 RS00100
gene id: 1123016:CL52_RS00100
uniprot id: A0A8D3XXJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1123016:CL52 RS11055
gene id: 1123016:CL52_RS11055
uniprot id: A0A8D3Y1K0
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1123016:CL52 RS17320
gene id: 1123016:CL52_RS17320
uniprot id: A0A8D3Y3W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1123016:CL52 RS14945
gene id: 1123016:CL52_RS14945
uniprot id: A0A8D3Y301
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS16745
gene id: 1123016:CL52_RS16745
uniprot id: A0A8D3Y3R8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1123016:CL52 RS17180
gene id: 1123016:CL52_RS17180
uniprot id: A0A8D3Y3M5
names: Similarity
messages: Belongs to the thioredoxin family.

1123016:CL52 RS06360
gene id: 1123016:CL52_RS06360
uniprot id: A0A8D4C6C8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1123016:CL52 RS07420
gene id: 1123016:CL52_RS07420
uniprot id: A0A8D4C288
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1123016:CL52 RS11340
gene id: 1123016:CL52_RS11340
uniprot id: A0A8D4C1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1123016:CL52 RS08360
gene id: 1123016:CL52_RS08360
uniprot id: A0A8D4C2G1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1123016:CL52 RS02830
gene id: 1123016:CL52_RS02830
uniprot id: A0A8D4C580
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1123016:CL52 RS01495
gene id: 1123016:CL52_RS01495
uniprot id: A0A8D4C5I5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1123016:CL52 RS03315
gene id: 1123016:CL52_RS03315
uniprot id: A0A8D3XYU7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1123016:CL52 RS15835
gene id: 1123016:CL52_RS15835
uniprot id: A0A8D3Y358
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1123016:CL52 RS17315
gene id: 1123016:CL52_RS17315
uniprot id: A0A8D3Y4G2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1123016:CL52 RS14220
gene id: 1123016:CL52_RS14220
uniprot id: A0A8D4C2G5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1123016:CL52 RS19085
gene id: 1123016:CL52_RS19085
uniprot id: A0A8D3Y4N0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123016:CL52 RS08255
gene id: 1123016:CL52_RS08255
uniprot id: A0A8D3Y0M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1123016:CL52 RS10210
gene id: 1123016:CL52_RS10210
uniprot id: A0A8D4C333
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1123016:CL52 RS12935
gene id: 1123016:CL52_RS12935
uniprot id: A0A8D4C722
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1123016:CL52 RS06830
gene id: 1123016:CL52_RS06830
uniprot id: A0A8D3Y0F4
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1123016:CL52 RS06725
gene id: 1123016:CL52_RS06725
uniprot id: A0A8D4C5Y1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1123016:CL52 RS04085
gene id: 1123016:CL52_RS04085
uniprot id: A0A8D4C5Z6
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1123016:CL52 RS01205
gene id: 1123016:CL52_RS01205
uniprot id: A0A8D3XY23
names: Similarity
messages: Belongs to the UPF0149 family.

1123016:CL52 RS09695
gene id: 1123016:CL52_RS09695
uniprot id: A0A8D3Y165
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ.

1123016:CL52 RS02600
gene id: 1123016:CL52_RS02600
uniprot id: A0A8D4C5Q5
names: Similarity
messages: Belongs to the glutamate synthase family.

1123016:CL52 RS10855
gene id: 1123016:CL52_RS10855
uniprot id: A0A8D3Y1L0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1123016:CL52 RS15750
gene id: 1123016:CL52_RS15750
uniprot id: A0A8D3Y3H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1123016:CL52 RS15140
gene id: 1123016:CL52_RS15140
uniprot id: A0A8D3Y3I8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1123016:CL52 RS13580
gene id: 1123016:CL52_RS13580
uniprot id: A0A8D4C7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1123016:CL52 RS04225
gene id: 1123016:CL52_RS04225
uniprot id: A0A8D3XYZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1123016:CL52 RS04885
gene id: 1123016:CL52_RS04885
uniprot id: A0A8D4C641
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS12135
gene id: 1123016:CL52_RS12135
uniprot id: A0A8D3Y290
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1123016:CL52 RS18810
gene id: 1123016:CL52_RS18810
uniprot id: A0A8D3Y505
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS13825
gene id: 1123016:CL52_RS13825
uniprot id: A0A8D3Y2M7
names: Similarity
messages: Belongs to the UPF0053 family.

1123016:CL52 RS15000
gene id: 1123016:CL52_RS15000
uniprot id: A0A8D3Y382
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1123016:CL52 RS16830
gene id: 1123016:CL52_RS16830
uniprot id: A0A8D3Y3I1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1123016:CL52 RS06765
gene id: 1123016:CL52_RS06765
uniprot id: A0A8D3Y0S5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1123016:CL52 RS19545
gene id: 1123016:CL52_RS19545
uniprot id: A0A8D4C8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS00730
gene id: 1123016:CL52_RS00730
uniprot id: A0A8D3XXP7
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17875
gene id: 1123016:CL52_RS17875
uniprot id: A0A8D4C803
names: Similarity
messages: Belongs to the UPF0250 family.

1123016:CL52 RS01480
gene id: 1123016:CL52_RS01480
uniprot id: A0A8D3XYQ9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1123016:CL52 RS10325
gene id: 1123016:CL52_RS10325
uniprot id: A0A8D3Y1S8
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1123016:CL52 RS15270
gene id: 1123016:CL52_RS15270
uniprot id: A0A8D4C7H4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1123016:CL52 RS17980
gene id: 1123016:CL52_RS17980
uniprot id: A0A8D3Y484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1123016:CL52 RS10250
gene id: 1123016:CL52_RS10250
uniprot id: A0A8D3Y1B0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1123016:CL52 RS19435
gene id: 1123016:CL52_RS19435
uniprot id: A0A8D4C4T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS05930
gene id: 1123016:CL52_RS05930
uniprot id: A0A8D3XZH3
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1123016:CL52 RS00400
gene id: 1123016:CL52_RS00400
uniprot id: A0A8D4C5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1123016:CL52 RS18960
gene id: 1123016:CL52_RS18960
uniprot id: A0A8D3Y526
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS17975
gene id: 1123016:CL52_RS17975
uniprot id: A0A8D3Y456
names: Similarity
messages: Belongs to the MotB family.

1123016:CL52 RS04015
gene id: 1123016:CL52_RS04015
uniprot id: A0A8D3XYZ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1123016:CL52 RS01875
gene id: 1123016:CL52_RS01875
uniprot id: A0A8D3XYV7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS16000
gene id: 1123016:CL52_RS16000
uniprot id: A0A8D4C826
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1123016:CL52 RS05920
gene id: 1123016:CL52_RS05920
uniprot id: A0A8D4C0U3
names: Similarity
messages: Belongs to the HesB/IscA family.

1123016:CL52 RS07110
gene id: 1123016:CL52_RS07110
uniprot id: A0A8D4C261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1123016:CL52 RS15210
gene id: 1123016:CL52_RS15210
uniprot id: A0A8D3Y329
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS02720
gene id: 1123016:CL52_RS02720
uniprot id: A0A8D3XZE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1123016:CL52 RS18020
gene id: 1123016:CL52_RS18020
uniprot id: A0A8D4C384
names: Similarity
messages: Belongs to the Smp family.

1123016:CL52 RS16660
gene id: 1123016:CL52_RS16660
uniprot id: A0A8D4C864
names: Cofactor
names: Similarity
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

1123016:CL52 RS18300
gene id: 1123016:CL52_RS18300
uniprot id: A0A8D4C8G8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS12765
gene id: 1123016:CL52_RS12765
uniprot id: A0A8D4C3M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1123016:CL52 RS17940
gene id: 1123016:CL52_RS17940
uniprot id: A0A8D3Y3V7
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS19720
gene id: 1123016:CL52_RS19720
uniprot id: A0A8D3Y4I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1123016:CL52 RS15920
gene id: 1123016:CL52_RS15920
uniprot id: A0A8D3Y420
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1123016:CL52 RS07200
gene id: 1123016:CL52_RS07200
uniprot id: A0A8D3Y0M1
names: Similarity
messages: Belongs to the fabD family.

1123016:CL52 RS17220
gene id: 1123016:CL52_RS17220
uniprot id: A0A8D4C7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1123016:CL52 RS06665
gene id: 1123016:CL52_RS06665
uniprot id: A0A8D3Y012
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1123016:CL52 RS02585
gene id: 1123016:CL52_RS02585
uniprot id: A0A8D3XZ44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS17380
gene id: 1123016:CL52_RS17380
uniprot id: A0A8D4C490
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1123016:CL52 RS08120
gene id: 1123016:CL52_RS08120
uniprot id: A0A8D4C185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1123016:CL52 RS19540
gene id: 1123016:CL52_RS19540
uniprot id: A0A8D3Y5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS07975
gene id: 1123016:CL52_RS07975
uniprot id: A0A8D4C2C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1123016:CL52 RS01255
gene id: 1123016:CL52_RS01255
uniprot id: A0A8D3XYM9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1123016:CL52 RS01425
gene id: 1123016:CL52_RS01425
uniprot id: A0A8D3XY09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS09940
gene id: 1123016:CL52_RS09940
uniprot id: A0A8D4C1L6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS00985
gene id: 1123016:CL52_RS00985
uniprot id: A0A8D4BZV2
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1123016:CL52 RS14200
gene id: 1123016:CL52_RS14200
uniprot id: A0A8D3Y2R0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1123016:CL52 RS12070
gene id: 1123016:CL52_RS12070
uniprot id: A0A8D4C7C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1123016:CL52 RS12705
gene id: 1123016:CL52_RS12705
uniprot id: A0A8D4C706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS17065
gene id: 1123016:CL52_RS17065
uniprot id: A0A8D4C319
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1123016:CL52 RS07260
gene id: 1123016:CL52_RS07260
uniprot id: A0A8D3Y004
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS06720
gene id: 1123016:CL52_RS06720
uniprot id: A0A8D4C0Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1123016:CL52 RS18870
gene id: 1123016:CL52_RS18870
uniprot id: A0A8D3Y4B0
names: Similarity
messages: Belongs to the peptidase M16 family.

1123016:CL52 RS06585
gene id: 1123016:CL52_RS06585
uniprot id: A0A8D3XZV8
names: Similarity
messages: Belongs to the ModE family.

1123016:CL52 RS16815
gene id: 1123016:CL52_RS16815
uniprot id: A0A8D3Y3N5
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1123016:CL52 RS00045
gene id: 1123016:CL52_RS00045
uniprot id: A0A8D4C4M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123016:CL52 RS06750
gene id: 1123016:CL52_RS06750
uniprot id: A0A8D3Y019
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1123016:CL52 RS09200
gene id: 1123016:CL52_RS09200
uniprot id: A0A8D4C6V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1123016:CL52 RS00190
gene id: 1123016:CL52_RS00190
uniprot id: A0A8D4BZP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS08890
gene id: 1123016:CL52_RS08890
uniprot id: A0A8D3Y1J6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1123016:CL52 RS16005
gene id: 1123016:CL52_RS16005
uniprot id: A0A8D3Y3D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1123016:CL52 RS07100
gene id: 1123016:CL52_RS07100
uniprot id: A0A8D4C605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1123016:CL52 RS18715
gene id: 1123016:CL52_RS18715
uniprot id: A0A8D4C857
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1123016:CL52 RS03675
gene id: 1123016:CL52_RS03675
uniprot id: A0A8D4C1G3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS00595
gene id: 1123016:CL52_RS00595
uniprot id: A0A8D3XY35
names: Similarity
names: Subunit
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.
messages: Monomer.

1123016:CL52 RS04280
gene id: 1123016:CL52_RS04280
uniprot id: A0A8D3XZA8
names: Similarity
messages: Belongs to the UPF0423 family.

1123016:CL52 RS07850
gene id: 1123016:CL52_RS07850
uniprot id: A0A8D3Y0C3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1123016:CL52 RS04355
gene id: 1123016:CL52_RS04355
uniprot id: A0A8D3XZC5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1123016:CL52 RS08140
gene id: 1123016:CL52_RS08140
uniprot id: A0A8D3Y0L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1123016:CL52 RS03690
gene id: 1123016:CL52_RS03690
uniprot id: A0A8D3XYY8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS12700
gene id: 1123016:CL52_RS12700
uniprot id: A0A8D4C251
names: Subcellular Location Annotation
messages: Cytoplasm

1123016:CL52 RS12040
gene id: 1123016:CL52_RS12040
uniprot id: A0A8D3Y1W6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1123016:CL52 RS02725
gene id: 1123016:CL52_RS02725
uniprot id: A0A8D4C5R0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1123016:CL52 RS04235
gene id: 1123016:CL52_RS04235
uniprot id: A0A8D4C603
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1123016:CL52 RS15045
gene id: 1123016:CL52_RS15045
uniprot id: A0A8D4C7F8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123016:CL52 RS02550
gene id: 1123016:CL52_RS02550
uniprot id: A0A8D4C054
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1123016:CL52 RS10070
gene id: 1123016:CL52_RS10070
uniprot id: A0A8D3Y1J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1123016:CL52 RS20180
gene id: 1123016:CL52_RS20180
uniprot id: A0A8D4C8U1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1123016:CL52 RS12310
gene id: 1123016:CL52_RS12310
uniprot id: A0A8D3Y244
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1123016:CL52 RS00625
gene id: 1123016:CL52_RS00625
uniprot id: A0A8D4C5C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1123016:CL52 RS16955
gene id: 1123016:CL52_RS16955
uniprot id: A0A8D3Y4F0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1123016:CL52 RS06085
gene id: 1123016:CL52_RS06085
uniprot id: A0A8D4C1Z1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1123016:CL52 RS03975
gene id: 1123016:CL52_RS03975
uniprot id: A0A8D4C1I7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1123016:CL52 RS08475
gene id: 1123016:CL52_RS08475
uniprot id: A0A8D3Y0Q7
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1123016:CL52 RS05750
gene id: 1123016:CL52_RS05750
uniprot id: A0A8D3XZP3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1123016:CL52 RS08770
gene id: 1123016:CL52_RS08770
uniprot id: A0A8D3Y0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS04545
gene id: 1123016:CL52_RS04545
uniprot id: A0A8D3Y000
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1123016:CL52 RS08725
gene id: 1123016:CL52_RS08725
uniprot id: A0A8D3Y0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1123016:CL52 RS14235
gene id: 1123016:CL52_RS14235
uniprot id: A0A8D4C3K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS11430
gene id: 1123016:CL52_RS11430
uniprot id: A0A8D4C1W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS03880
gene id: 1123016:CL52_RS03880
uniprot id: A0A8D3XYU2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1123016:CL52 RS15720
gene id: 1123016:CL52_RS15720
uniprot id: A0A8D4C7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1123016:CL52 RS06040
gene id: 1123016:CL52_RS06040
uniprot id: A0A8D3Y0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS15830
gene id: 1123016:CL52_RS15830
uniprot id: A0A8D3Y3I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1123016:CL52 RS07175
gene id: 1123016:CL52_RS07175
uniprot id: A0A8D4C610
names: Similarity
messages: Belongs to the peptidase S49 family.

1123016:CL52 RS10475
gene id: 1123016:CL52_RS10475
uniprot id: A0A8D3Y189
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS01845
gene id: 1123016:CL52_RS01845
uniprot id: A0A8D4C511
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1123016:CL52 RS08705
gene id: 1123016:CL52_RS08705
uniprot id: A0A8D3Y137
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS00850
gene id: 1123016:CL52_RS00850
uniprot id: A0A8D4C0X1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1123016:CL52 RS13690
gene id: 1123016:CL52_RS13690
uniprot id: A0A8D3Y2E8
names: Similarity
messages: Belongs to the ArsC family.

1123016:CL52 RS11935
gene id: 1123016:CL52_RS11935
uniprot id: A0A8D4C1Z8
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial renalase family.
messages: Catalyzes the oxidation of the 1,2-dihydro- and 1,6-dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P)+. May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS01230
gene id: 1123016:CL52_RS01230
uniprot id: A0A8D3XXV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS08150
gene id: 1123016:CL52_RS08150
uniprot id: A0A8D3Y0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS18625
gene id: 1123016:CL52_RS18625
uniprot id: A0A8D4C516
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS14050
gene id: 1123016:CL52_RS14050
uniprot id: A0A8D3Y2Q7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1123016:CL52 RS19890
gene id: 1123016:CL52_RS19890
uniprot id: A0A8D4C3M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123016:CL52 RS04035
gene id: 1123016:CL52_RS04035
uniprot id: A0A8D4C0F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1123016:CL52 RS18385
gene id: 1123016:CL52_RS18385
uniprot id: A0A8D3Y471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1123016:CL52 RS13480
gene id: 1123016:CL52_RS13480
uniprot id: A0A8D3Y2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1123016:CL52 RS15170
gene id: 1123016:CL52_RS15170
uniprot id: A0A8D3Y327
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1123016:CL52 RS11165
gene id: 1123016:CL52_RS11165
uniprot id: A0A8D4C767
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1123016:CL52 RS06265
gene id: 1123016:CL52_RS06265
uniprot id: A0A8D3XZX0
names: Similarity
messages: Belongs to the pirin family.

1123016:CL52 RS11765
gene id: 1123016:CL52_RS11765
uniprot id: A0A8D3Y1Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1123016:CL52 RS02520
gene id: 1123016:CL52_RS02520
uniprot id: A0A8D4C5Q1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS12685
gene id: 1123016:CL52_RS12685
uniprot id: A0A8D3Y294
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS07155
gene id: 1123016:CL52_RS07155
uniprot id: A0A8D3Y0A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1123016:CL52 RS15680
gene id: 1123016:CL52_RS15680
uniprot id: A0A8D3Y340
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1123016:CL52 RS20025
gene id: 1123016:CL52_RS20025
uniprot id: A0A8D3Y4R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1123016:CL52 RS00995
gene id: 1123016:CL52_RS00995
uniprot id: A0A8D3XXS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1123016:CL52 RS10670
gene id: 1123016:CL52_RS10670
uniprot id: A0A8D3Y1B1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1123016:CL52 RS17960
gene id: 1123016:CL52_RS17960
uniprot id: A0A8D4C4C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1123016:CL52 RS06015
gene id: 1123016:CL52_RS06015
uniprot id: A0A8D3XZW6
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1123016:CL52 RS00110
gene id: 1123016:CL52_RS00110
uniprot id: A0A8D3XXD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1123016:CL52 RS11245
gene id: 1123016:CL52_RS11245
uniprot id: A0A8D3Y1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS08650
gene id: 1123016:CL52_RS08650
uniprot id: A0A8D4C2S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1123016:CL52 RS13645
gene id: 1123016:CL52_RS13645
uniprot id: A0A8D3Y2E1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS11770
gene id: 1123016:CL52_RS11770
uniprot id: A0A8D4C325
names: Similarity
messages: Belongs to the YkuD family.

1123016:CL52 RS17145
gene id: 1123016:CL52_RS17145
uniprot id: A0A8D4C7V4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1123016:CL52 RS12640
gene id: 1123016:CL52_RS12640
uniprot id: A0A8D4C385
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1123016:CL52 RS09895
gene id: 1123016:CL52_RS09895
uniprot id: A0A8D3Y161
names: Similarity
messages: Belongs to the HIBADH-related family.

1123016:CL52 RS02715
gene id: 1123016:CL52_RS02715
uniprot id: A0A8D3XYF0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1123016:CL52 RS18910
gene id: 1123016:CL52_RS18910
uniprot id: A0A8D4C8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1123016:CL52 RS09415
gene id: 1123016:CL52_RS09415
uniprot id: A0A8D3Y1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

1123016:CL52 RS05135
gene id: 1123016:CL52_RS05135
uniprot id: A0A8D3XZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1123016:CL52 RS04790
gene id: 1123016:CL52_RS04790
uniprot id: A0A8D3XZR7
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1123016:CL52 RS19090
gene id: 1123016:CL52_RS19090
uniprot id: A0A8D4C554
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1123016:CL52 RS00075
gene id: 1123016:CL52_RS00075
uniprot id: A0A8D3XY95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS19725
gene id: 1123016:CL52_RS19725
uniprot id: A0A8D4C3K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1123016:CL52 RS18690
gene id: 1123016:CL52_RS18690
uniprot id: A0A8D3Y4B4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1123016:CL52 RS05680
gene id: 1123016:CL52_RS05680
uniprot id: A0A8D4C241
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1123016:CL52 RS16525
gene id: 1123016:CL52_RS16525
uniprot id: A0A8D3Y4W0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS14475
gene id: 1123016:CL52_RS14475
uniprot id: A0A8D3Y2P5
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS10440
gene id: 1123016:CL52_RS10440
uniprot id: A0A8D3Y1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1123016:CL52 RS01865
gene id: 1123016:CL52_RS01865
uniprot id: A0A8D3XYI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS16625
gene id: 1123016:CL52_RS16625
uniprot id: A0A8D4C431
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS09750
gene id: 1123016:CL52_RS09750
uniprot id: A0A8D3Y1F6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1123016:CL52 RS18260
gene id: 1123016:CL52_RS18260
uniprot id: A0A8D3Y429
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1123016:CL52 RS12110
gene id: 1123016:CL52_RS12110
uniprot id: A0A8D3Y1U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1123016:CL52 RS17840
gene id: 1123016:CL52_RS17840
uniprot id: A0A8D3Y4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1123016:CL52 RS06950
gene id: 1123016:CL52_RS06950
uniprot id: A0A8D4C5Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1123016:CL52 RS12245
gene id: 1123016:CL52_RS12245
uniprot id: A0A8D3Y1V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1123016:CL52 RS19245
gene id: 1123016:CL52_RS19245
uniprot id: A0A8D3Y4C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123016:CL52 RS03335
gene id: 1123016:CL52_RS03335
uniprot id: A0A8D4C5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1123016:CL52 RS19495
gene id: 1123016:CL52_RS19495
uniprot id: A0A8D4C3J0
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1123016:CL52 RS19215
gene id: 1123016:CL52_RS19215
uniprot id: A0A8D3Y4D1
names: Similarity
messages: Belongs to the YkuD family.

1123016:CL52 RS11465
gene id: 1123016:CL52_RS11465
uniprot id: A0A8D3Y209
names: Similarity
messages: Belongs to the TrpF family.

1123016:CL52 RS04425
gene id: 1123016:CL52_RS04425
uniprot id: A0A8D4C5I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1123016:CL52 RS13830
gene id: 1123016:CL52_RS13830
uniprot id: A0A8D4C3V5
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS04800
gene id: 1123016:CL52_RS04800
uniprot id: A0A8D3Y018
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1123016:CL52 RS11105
gene id: 1123016:CL52_RS11105
uniprot id: A0A8D3Y1G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1123016:CL52 RS10080
gene id: 1123016:CL52_RS10080
uniprot id: A0A8D3Y1Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1123016:CL52 RS18030
gene id: 1123016:CL52_RS18030
uniprot id: A0A8D3Y3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1123016:CL52 RS17610
gene id: 1123016:CL52_RS17610
uniprot id: A0A8D3Y3S7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS16025
gene id: 1123016:CL52_RS16025
uniprot id: A0A8D4C2U6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1123016:CL52 RS15010
gene id: 1123016:CL52_RS15010
uniprot id: A0A8D3Y3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1123016:CL52 RS19150
gene id: 1123016:CL52_RS19150
uniprot id: A0A8D4C8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS08885
gene id: 1123016:CL52_RS08885
uniprot id: A0A8D3Y0Q6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS15100
gene id: 1123016:CL52_RS15100
uniprot id: A0A8D3Y343
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123016:CL52 RS19060
gene id: 1123016:CL52_RS19060
uniprot id: A0A8D3Y4B1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1123016:CL52 RS19415
gene id: 1123016:CL52_RS19415
uniprot id: A0A8D3Y4E7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1123016:CL52 RS15260
gene id: 1123016:CL52_RS15260
uniprot id: A0A8D3Y2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS20080
gene id: 1123016:CL52_RS20080
uniprot id: A0A8D3Y4Z1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1123016:CL52 RS04835
gene id: 1123016:CL52_RS04835
uniprot id: A0A8D4C0L4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1123016:CL52 RS10860
gene id: 1123016:CL52_RS10860
uniprot id: A0A8D4C376
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS13290
gene id: 1123016:CL52_RS13290
uniprot id: A0A8D3Y2D0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1123016:CL52 RS17275
gene id: 1123016:CL52_RS17275
uniprot id: A0A8D3Y3Y6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1123016:CL52 RS19870
gene id: 1123016:CL52_RS19870
uniprot id: A0A8D3Y4P6
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17870
gene id: 1123016:CL52_RS17870
uniprot id: A0A8D4C374
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1123016:CL52 RS00040
gene id: 1123016:CL52_RS00040
uniprot id: A0A8D4BZN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1123016:CL52 RS01170
gene id: 1123016:CL52_RS01170
uniprot id: A0A8D3XYA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1123016:CL52 RS00230
gene id: 1123016:CL52_RS00230
uniprot id: A0A8D3XXF6
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1123016:CL52 RS10100
gene id: 1123016:CL52_RS10100
uniprot id: A0A8D4C326
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1123016:CL52 RS02640
gene id: 1123016:CL52_RS02640
uniprot id: A0A8D4C198
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1123016:CL52 RS08365
gene id: 1123016:CL52_RS08365
uniprot id: A0A8D3Y0N7
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS09890
gene id: 1123016:CL52_RS09890
uniprot id: A0A8D3Y1N2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1123016:CL52 RS15395
gene id: 1123016:CL52_RS15395
uniprot id: A0A8D3Y357
names: Similarity
messages: Belongs to the pyruvate kinase family.

1123016:CL52 RS10075
gene id: 1123016:CL52_RS10075
uniprot id: A0A8D3Y143
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1123016:CL52 RS18125
gene id: 1123016:CL52_RS18125
uniprot id: A0A8D3Y476
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS00555
gene id: 1123016:CL52_RS00555
uniprot id: A0A8D3XXN2
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1123016:CL52 RS13275
gene id: 1123016:CL52_RS13275
uniprot id: A0A8D3Y2A0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1123016:CL52 RS07230
gene id: 1123016:CL52_RS07230
uniprot id: A0A8D3Y090
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1123016:CL52 RS02970
gene id: 1123016:CL52_RS02970
uniprot id: A0A8D4C5S5
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS18575
gene id: 1123016:CL52_RS18575
uniprot id: A0A8D4C4M3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

1123016:CL52 RS01720
gene id: 1123016:CL52_RS01720
uniprot id: A0A8D3XYU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1123016:CL52 RS01500
gene id: 1123016:CL52_RS01500
uniprot id: A0A8D3XY22
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS03760
gene id: 1123016:CL52_RS03760
uniprot id: A0A8D3XZ83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123016:CL52 RS03455
gene id: 1123016:CL52_RS03455
uniprot id: A0A8D3XYN5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1123016:CL52 RS02960
gene id: 1123016:CL52_RS02960
uniprot id: A0A8D3XYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS00725
gene id: 1123016:CL52_RS00725
uniprot id: A0A8D4C110
names: Similarity
messages: Belongs to the universal stress protein A family.

1123016:CL52 RS17925
gene id: 1123016:CL52_RS17925
uniprot id: A0A8D3Y416
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1123016:CL52 RS04185
gene id: 1123016:CL52_RS04185
uniprot id: A0A8D4C0G7
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1123016:CL52 RS18285
gene id: 1123016:CL52_RS18285
uniprot id: A0A8D3Y4B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS07630
gene id: 1123016:CL52_RS07630
uniprot id: A0A8D3Y0C1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1123016:CL52 RS18490
gene id: 1123016:CL52_RS18490
uniprot id: A0A8D4C841
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1123016:CL52 RS17400
gene id: 1123016:CL52_RS17400
uniprot id: A0A8D3Y417
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1123016:CL52 RS15695
gene id: 1123016:CL52_RS15695
uniprot id: A0A8D3Y392
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1123016:CL52 RS07870
gene id: 1123016:CL52_RS07870
uniprot id: A0A8D3Y0I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1123016:CL52 RS05890
gene id: 1123016:CL52_RS05890
uniprot id: A0A8D3Y0G0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1123016:CL52 RS15095
gene id: 1123016:CL52_RS15095
uniprot id: A0A8D3Y319
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123016:CL52 RS15885
gene id: 1123016:CL52_RS15885
uniprot id: A0A8D3Y390
names: Similarity
messages: Belongs to the BolA/IbaG family.

1123016:CL52 RS02250
gene id: 1123016:CL52_RS02250
uniprot id: A0A8D3XYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1123016:CL52 RS16570
gene id: 1123016:CL52_RS16570
uniprot id: A0A8D3Y3R4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS18615
gene id: 1123016:CL52_RS18615
uniprot id: A0A8D3Y4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1123016:CL52 RS07840
gene id: 1123016:CL52_RS07840
uniprot id: A0A8D3Y0F6
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS07190
gene id: 1123016:CL52_RS07190
uniprot id: A0A8D4C268
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1123016:CL52 RS11210
gene id: 1123016:CL52_RS11210
uniprot id: A0A8D3Y1L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS17650
gene id: 1123016:CL52_RS17650
uniprot id: A0A8D4C7Y7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1123016:CL52 RS05935
gene id: 1123016:CL52_RS05935
uniprot id: A0A8D4C1Y0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1123016:CL52 RS13725
gene id: 1123016:CL52_RS13725
uniprot id: A0A8D3Y389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1123016:CL52 RS18845
gene id: 1123016:CL52_RS18845
uniprot id: A0A8D3Y4K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1123016:CL52 RS06450
gene id: 1123016:CL52_RS06450
uniprot id: A0A8D3XZZ7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

1123016:CL52 RS07385
gene id: 1123016:CL52_RS07385
uniprot id: A0A8D3Y0B1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1123016:CL52 RS02425
gene id: 1123016:CL52_RS02425
uniprot id: A0A8D3XZ30
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

1123016:CL52 RS08090
gene id: 1123016:CL52_RS08090
uniprot id: A0A8D3Y0K5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1123016:CL52 RS00245
gene id: 1123016:CL52_RS00245
uniprot id: A0A8D3XXG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1123016:CL52 RS19710
gene id: 1123016:CL52_RS19710
uniprot id: A0A8D3Y4W9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1123016:CL52 RS14070
gene id: 1123016:CL52_RS14070
uniprot id: A0A8D4C793
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1123016:CL52 RS01580
gene id: 1123016:CL52_RS01580
uniprot id: A0A8D3XY80
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1123016:CL52 RS01855
gene id: 1123016:CL52_RS01855
uniprot id: A0A8D4C135
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS01180
gene id: 1123016:CL52_RS01180
uniprot id: A0A8D3XYM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1123016:CL52 RS17560
gene id: 1123016:CL52_RS17560
uniprot id: A0A8D3Y3S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1123016:CL52 RS00325
gene id: 1123016:CL52_RS00325
uniprot id: A0A8D3XXQ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS13250
gene id: 1123016:CL52_RS13250
uniprot id: A0A8D3Y2G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS15560
gene id: 1123016:CL52_RS15560
uniprot id: A0A8D3Y330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1123016:CL52 RS00050
gene id: 1123016:CL52_RS00050
uniprot id: A0A8D3XX84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123016:CL52 RS15055
gene id: 1123016:CL52_RS15055
uniprot id: A0A8D4C3R3
names: Function
names: Similarity
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.

1123016:CL52 RS16580
gene id: 1123016:CL52_RS16580
uniprot id: A0A8D3Y4A1
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1123016:CL52 RS12925
gene id: 1123016:CL52_RS12925
uniprot id: A0A8D3Y250
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1123016:CL52 RS10755
gene id: 1123016:CL52_RS10755
uniprot id: A0A8D3Y1S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS11525
gene id: 1123016:CL52_RS11525
uniprot id: A0A8D3Y1R2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS09275
gene id: 1123016:CL52_RS09275
uniprot id: A0A8D4C6W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS09860
gene id: 1123016:CL52_RS09860
uniprot id: A0A8D3Y120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS19815
gene id: 1123016:CL52_RS19815
uniprot id: A0A8D4C3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1123016:CL52 RS12820
gene id: 1123016:CL52_RS12820
uniprot id: A0A8D3Y238
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123016:CL52 RS05235
gene id: 1123016:CL52_RS05235
uniprot id: A0A8D4C5M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1123016:CL52 RS15715
gene id: 1123016:CL52_RS15715
uniprot id: A0A8D4C2R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS03885
gene id: 1123016:CL52_RS03885
uniprot id: A0A8D4C0D8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1123016:CL52 RS04480
gene id: 1123016:CL52_RS04480
uniprot id: A0A8D3XZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1123016:CL52 RS12340
gene id: 1123016:CL52_RS12340
uniprot id: A0A8D4C365
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1123016:CL52 RS06325
gene id: 1123016:CL52_RS06325
uniprot id: A0A8D4C209
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1123016:CL52 RS02110
gene id: 1123016:CL52_RS02110
uniprot id: A0A8D3XZ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1123016:CL52 RS17125
gene id: 1123016:CL52_RS17125
uniprot id: A0A8D3Y3W8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1123016:CL52 RS15150
gene id: 1123016:CL52_RS15150
uniprot id: A0A8D3Y3A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1123016:CL52 RS11275
gene id: 1123016:CL52_RS11275
uniprot id: A0A8D3Y1J4
names: Similarity
messages: Belongs to the peptidase M1 family.

1123016:CL52 RS17395
gene id: 1123016:CL52_RS17395
uniprot id: A0A8D3Y3X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1123016:CL52 RS18525
gene id: 1123016:CL52_RS18525
uniprot id: A0A8D3Y434
names: Similarity
messages: Belongs to the clavaminate synthase family.

1123016:CL52 RS19860
gene id: 1123016:CL52_RS19860
uniprot id: A0A8D3Y5E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1123016:CL52 RS09095
gene id: 1123016:CL52_RS09095
uniprot id: A0A8D3Y1C3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1123016:CL52 RS15700
gene id: 1123016:CL52_RS15700
uniprot id: A0A8D3Y3C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1123016:CL52 RS17440
gene id: 1123016:CL52_RS17440
uniprot id: A0A8D4C345
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1123016:CL52 RS13775
gene id: 1123016:CL52_RS13775
uniprot id: A0A8D3Y2I9
names: Similarity
messages: Belongs to the SufE family.

1123016:CL52 RS19735
gene id: 1123016:CL52_RS19735
uniprot id: A0A8D3Y4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS15785
gene id: 1123016:CL52_RS15785
uniprot id: A0A8D4C4B0
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1123016:CL52 RS09195
gene id: 1123016:CL52_RS09195
uniprot id: A0A8D3Y1N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1123016:CL52 RS00105
gene id: 1123016:CL52_RS00105
uniprot id: A0A8D4C0X4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1123016:CL52 RS05775
gene id: 1123016:CL52_RS05775
uniprot id: A0A8D3XZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1123016:CL52 RS04325
gene id: 1123016:CL52_RS04325
uniprot id: A0A8D4C1U6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS09140
gene id: 1123016:CL52_RS09140
uniprot id: A0A8D3Y0S9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1123016:CL52 RS16825
gene id: 1123016:CL52_RS16825
uniprot id: A0A8D4C4M6
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1123016:CL52 RS03955
gene id: 1123016:CL52_RS03955
uniprot id: A0A8D3XYV0
names: Similarity
messages: Belongs to the peptidase S16 family.

1123016:CL52 RS18395
gene id: 1123016:CL52_RS18395
uniprot id: A0A8D4C4Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123016:CL52 RS19955
gene id: 1123016:CL52_RS19955
uniprot id: A0A8D3Y4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1123016:CL52 RS17355
gene id: 1123016:CL52_RS17355
uniprot id: A0A8D4C4R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1123016:CL52 RS00255
gene id: 1123016:CL52_RS00255
uniprot id: A0A8D4C0Y2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS09795
gene id: 1123016:CL52_RS09795
uniprot id: A0A8D4C6H3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1123016:CL52 RS00405
gene id: 1123016:CL52_RS00405
uniprot id: A0A8D3XXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1123016:CL52 RS11060
gene id: 1123016:CL52_RS11060
uniprot id: A0A8D3Y223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS05980
gene id: 1123016:CL52_RS05980
uniprot id: A0A8D3XZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1123016:CL52 RS17770
gene id: 1123016:CL52_RS17770
uniprot id: A0A8D4C8D1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS00855
gene id: 1123016:CL52_RS00855
uniprot id: A0A8D3XY63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1123016:CL52 RS17970
gene id: 1123016:CL52_RS17970
uniprot id: A0A8D3Y4N9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1123016:CL52 RS04560
gene id: 1123016:CL52_RS04560
uniprot id: A0A8D3XZA1
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS07780
gene id: 1123016:CL52_RS07780
uniprot id: A0A8D3Y155
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1123016:CL52 RS11180
gene id: 1123016:CL52_RS11180
uniprot id: A0A8D4C3A5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1123016:CL52 RS03485
gene id: 1123016:CL52_RS03485
uniprot id: A0A8D3XYS6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1123016:CL52 RS05780
gene id: 1123016:CL52_RS05780
uniprot id: A0A8D4C1X0
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS00120
gene id: 1123016:CL52_RS00120
uniprot id: A0A8D4C4N1
names: Similarity
messages: Belongs to the DprA/Smf family.

1123016:CL52 RS10125
gene id: 1123016:CL52_RS10125
uniprot id: A0A8D3Y175
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1123016:CL52 RS14065
gene id: 1123016:CL52_RS14065
uniprot id: A0A8D4C2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1123016:CL52 RS13565
gene id: 1123016:CL52_RS13565
uniprot id: A0A8D3Y2Q9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS15290
gene id: 1123016:CL52_RS15290
uniprot id: A0A8D3Y3L7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1123016:CL52 RS06205
gene id: 1123016:CL52_RS06205
uniprot id: A0A8D4C6B8
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1123016:CL52 RS08400
gene id: 1123016:CL52_RS08400
uniprot id: A0A8D3Y0P7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1123016:CL52 RS17290
gene id: 1123016:CL52_RS17290
uniprot id: A0A8D4C336
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1123016:CL52 RS06395
gene id: 1123016:CL52_RS06395
uniprot id: A0A8D4C5V7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS13650
gene id: 1123016:CL52_RS13650
uniprot id: A0A8D3Y380
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1123016:CL52 RS14490
gene id: 1123016:CL52_RS14490
uniprot id: A0A8D3Y2Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 4-oxalocrotonate tautomerase family.
messages: Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.
messages: Homohexamer.

1123016:CL52 RS00805
gene id: 1123016:CL52_RS00805
uniprot id: A0A8D4C5D7
names: PTM
messages: Binds 1 heme group per subunit.

1123016:CL52 RS06875
gene id: 1123016:CL52_RS06875
uniprot id: A0A8D4C5Y7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS05645
gene id: 1123016:CL52_RS05645
uniprot id: A0A8D3XZP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1123016:CL52 RS07325
gene id: 1123016:CL52_RS07325
uniprot id: A0A8D3Y074
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1123016:CL52 RS15190
gene id: 1123016:CL52_RS15190
uniprot id: A0A8D4C2M9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1123016:CL52 RS17410
gene id: 1123016:CL52_RS17410
uniprot id: A0A8D3Y4K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1123016:CL52 RS06890
gene id: 1123016:CL52_RS06890
uniprot id: A0A8D3Y078
names: Similarity
messages: Belongs to the UPF0270 family.

1123016:CL52 RS13620
gene id: 1123016:CL52_RS13620
uniprot id: A0A8D4C3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1123016:CL52 RS19325
gene id: 1123016:CL52_RS19325
uniprot id: A0A8D3Y4H7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1123016:CL52 RS13595
gene id: 1123016:CL52_RS13595
uniprot id: A0A8D4C3T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1123016:CL52 RS00125
gene id: 1123016:CL52_RS00125
uniprot id: A0A8D3XXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1123016:CL52 RS17420
gene id: 1123016:CL52_RS17420
uniprot id: A0A8D3Y3V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1123016:CL52 RS02015
gene id: 1123016:CL52_RS02015
uniprot id: A0A8D3XYK4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1123016:CL52 RS03165
gene id: 1123016:CL52_RS03165
uniprot id: A0A8D4C1J1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1123016:CL52 RS16535
gene id: 1123016:CL52_RS16535
uniprot id: A0A8D4C2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

1123016:CL52 RS19400
gene id: 1123016:CL52_RS19400
uniprot id: A0A8D3Y4I7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS14085
gene id: 1123016:CL52_RS14085
uniprot id: A0A8D3Y2N6
names: Similarity
messages: Belongs to the GST superfamily.

1123016:CL52 RS04350
gene id: 1123016:CL52_RS04350
uniprot id: A0A8D4C1M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1123016:CL52 RS04485
gene id: 1123016:CL52_RS04485
uniprot id: A0A8D4C1V6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1123016:CL52 RS11490
gene id: 1123016:CL52_RS11490
uniprot id: A0A8D3Y1U2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS08185
gene id: 1123016:CL52_RS08185
uniprot id: A0A8D4C2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1123016:CL52 RS00515
gene id: 1123016:CL52_RS00515
uniprot id: A0A8D4C0U8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1123016:CL52 RS00200
gene id: 1123016:CL52_RS00200
uniprot id: A0A8D3XXF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS01745
gene id: 1123016:CL52_RS01745
uniprot id: A0A8D3XY99
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS11915
gene id: 1123016:CL52_RS11915
uniprot id: A0A8D3Y1Y4
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1123016:CL52 RS17085
gene id: 1123016:CL52_RS17085
uniprot id: A0A8D3Y3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1123016:CL52 RS11095
gene id: 1123016:CL52_RS11095
uniprot id: A0A8D3Y1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1123016:CL52 RS05700
gene id: 1123016:CL52_RS05700
uniprot id: A0A8D3XZE6
names: Function
messages: May be involved in the biogenesis of curli organelles.

1123016:CL52 RS15085
gene id: 1123016:CL52_RS15085
uniprot id: A0A8D3Y3Q4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1123016:CL52 RS11575
gene id: 1123016:CL52_RS11575
uniprot id: A0A8D3Y1V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

1123016:CL52 RS16765
gene id: 1123016:CL52_RS16765
uniprot id: A0A8D4C7S5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1123016:CL52 RS15550
gene id: 1123016:CL52_RS15550
uniprot id: A0A8D3Y3A4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123016:CL52 RS05740
gene id: 1123016:CL52_RS05740
uniprot id: A0A8D4C689
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1123016:CL52 RS13305
gene id: 1123016:CL52_RS13305
uniprot id: A0A8D3Y2V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1123016:CL52 RS18310
gene id: 1123016:CL52_RS18310
uniprot id: A0A8D3Y4C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

1123016:CL52 RS02940
gene id: 1123016:CL52_RS02940
uniprot id: A0A8D3XYW5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1123016:CL52 RS11800
gene id: 1123016:CL52_RS11800
uniprot id: A0A8D3Y2J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1123016:CL52 RS16500
gene id: 1123016:CL52_RS16500
uniprot id: A0A8D3Y485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS07670
gene id: 1123016:CL52_RS07670
uniprot id: A0A8D3Y0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

1123016:CL52 RS08045
gene id: 1123016:CL52_RS08045
uniprot id: A0A8D3Y0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

1123016:CL52 RS19330
gene id: 1123016:CL52_RS19330
uniprot id: A0A8D3Y4R1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1123016:CL52 RS01335
gene id: 1123016:CL52_RS01335
uniprot id: A0A8D3XXW7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1123016:CL52 RS16030
gene id: 1123016:CL52_RS16030
uniprot id: A0A8D4C7N1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1123016:CL52 RS16565
gene id: 1123016:CL52_RS16565
uniprot id: A0A8D3Y3L1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1123016:CL52 RS14325
gene id: 1123016:CL52_RS14325
uniprot id: A0A8D4C3K9
names: Subcellular Location Annotation
messages: Cytoplasm

1123016:CL52 RS09460
gene id: 1123016:CL52_RS09460
uniprot id: A0A8D3Y0X0
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17070
gene id: 1123016:CL52_RS17070
uniprot id: A0A8D4C7U8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1123016:CL52 RS00290
gene id: 1123016:CL52_RS00290
uniprot id: A0A8D3XXY2
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS05870
gene id: 1123016:CL52_RS05870
uniprot id: A0A8D3Y020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS05685
gene id: 1123016:CL52_RS05685
uniprot id: A0A8D3XZL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

1123016:CL52 RS19980
gene id: 1123016:CL52_RS19980
uniprot id: A0A8D3Y4N5
names: Similarity
messages: Belongs to the fabD family.

1123016:CL52 RS02495
gene id: 1123016:CL52_RS02495
uniprot id: A0A8D3XYS1
names: Similarity
messages: Belongs to the thioredoxin family.

1123016:CL52 RS02105
gene id: 1123016:CL52_RS02105
uniprot id: A0A8D3XY66
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1123016:CL52 RS19595
gene id: 1123016:CL52_RS19595
uniprot id: A0A8D3Y5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1123016:CL52 RS01420
gene id: 1123016:CL52_RS01420
uniprot id: A0A8D4C5I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS12385
gene id: 1123016:CL52_RS12385
uniprot id: A0A8D4C3J7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1123016:CL52 RS12490
gene id: 1123016:CL52_RS12490
uniprot id: A0A8D3Y230
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1123016:CL52 RS16980
gene id: 1123016:CL52_RS16980
uniprot id: A0A8D3Y3J8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1123016:CL52 RS03755
gene id: 1123016:CL52_RS03755
uniprot id: A0A8D3XZ40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1123016:CL52 RS13890
gene id: 1123016:CL52_RS13890
uniprot id: A0A8D4C7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS04895
gene id: 1123016:CL52_RS04895
uniprot id: A0A8D3XZE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS08085
gene id: 1123016:CL52_RS08085
uniprot id: A0A8D4C6P1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1123016:CL52 RS01775
gene id: 1123016:CL52_RS01775
uniprot id: A0A8D3XY29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

1123016:CL52 RS15215
gene id: 1123016:CL52_RS15215
uniprot id: A0A8D3Y3K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1123016:CL52 RS18925
gene id: 1123016:CL52_RS18925
uniprot id: A0A8D4C539
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123016:CL52 RS18065
gene id: 1123016:CL52_RS18065
uniprot id: A0A8D3Y4T9
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1123016:CL52 RS14005
gene id: 1123016:CL52_RS14005
uniprot id: A0A8D4C3I5
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

1123016:CL52 RS07050
gene id: 1123016:CL52_RS07050
uniprot id: A0A8D3Y064
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1123016:CL52 RS17590
gene id: 1123016:CL52_RS17590
uniprot id: A0A8D3Y400
names: Similarity
messages: Belongs to the globin family.

1123016:CL52 RS15575
gene id: 1123016:CL52_RS15575
uniprot id: A0A8D3Y345
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1123016:CL52 RS15925
gene id: 1123016:CL52_RS15925
uniprot id: A0A8D4C821
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1123016:CL52 RS03180
gene id: 1123016:CL52_RS03180
uniprot id: A0A8D4C598
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS18850
gene id: 1123016:CL52_RS18850
uniprot id: A0A8D4C532
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1123016:CL52 RS08450
gene id: 1123016:CL52_RS08450
uniprot id: A0A8D3Y0N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1123016:CL52 RS17350
gene id: 1123016:CL52_RS17350
uniprot id: A0A8D3Y402
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1123016:CL52 RS17895
gene id: 1123016:CL52_RS17895
uniprot id: A0A8D3Y4N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1123016:CL52 RS08915
gene id: 1123016:CL52_RS08915
uniprot id: A0A8D3Y0Q8
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1123016:CL52 RS08630
gene id: 1123016:CL52_RS08630
uniprot id: A0A8D3Y1G5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1123016:CL52 RS18270
gene id: 1123016:CL52_RS18270
uniprot id: A0A8D3Y482
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1123016:CL52 RS11250
gene id: 1123016:CL52_RS11250
uniprot id: A0A8D3Y1R3
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS06310
gene id: 1123016:CL52_RS06310
uniprot id: A0A8D4C0X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1123016:CL52 RS15305
gene id: 1123016:CL52_RS15305
uniprot id: A0A8D3Y2Y9
names: Similarity
messages: Belongs to the PhoH family.

1123016:CL52 RS04310
gene id: 1123016:CL52_RS04310
uniprot id: A0A8D4C607
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1123016:CL52 RS20225
gene id: 1123016:CL52_RS20225
uniprot id: A0A8D3Y4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1123016:CL52 RS02825
gene id: 1123016:CL52_RS02825
uniprot id: A0A8D4C069
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1123016:CL52 RS06815
gene id: 1123016:CL52_RS06815
uniprot id: A0A8D3Y069
names: Similarity
messages: Belongs to the peptidase M18 family.

1123016:CL52 RS10540
gene id: 1123016:CL52_RS10540
uniprot id: A0A8D3Y1H1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1123016:CL52 RS15340
gene id: 1123016:CL52_RS15340
uniprot id: A0A8D4C2P0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1123016:CL52 RS03275
gene id: 1123016:CL52_RS03275
uniprot id: A0A8D3XYZ2
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1123016:CL52 RS07475
gene id: 1123016:CL52_RS07475
uniprot id: A0A8D3Y099
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1123016:CL52 RS08350
gene id: 1123016:CL52_RS08350
uniprot id: A0A8D4C688
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

1123016:CL52 RS12045
gene id: 1123016:CL52_RS12045
uniprot id: A0A8D3Y2E0
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1123016:CL52 RS05075
gene id: 1123016:CL52_RS05075
uniprot id: A0A8D3XZD8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1123016:CL52 RS15110
gene id: 1123016:CL52_RS15110
uniprot id: A0A8D3Y2X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123016:CL52 RS08975
gene id: 1123016:CL52_RS08975
uniprot id: A0A8D3Y0W3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1123016:CL52 RS15120
gene id: 1123016:CL52_RS15120
uniprot id: A0A8D4C7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123016:CL52 RS03765
gene id: 1123016:CL52_RS03765
uniprot id: A0A8D3XYZ6
names: Function
messages: Binds zinc. Could be an important component of the zinc-balancing mechanism.

1123016:CL52 RS07915
gene id: 1123016:CL52_RS07915
uniprot id: A0A8D3Y0G5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1123016:CL52 RS19715
gene id: 1123016:CL52_RS19715
uniprot id: A0A8D4C596
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123016:CL52 RS05790
gene id: 1123016:CL52_RS05790
uniprot id: A0A8D3Y010
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1123016:CL52 RS14320
gene id: 1123016:CL52_RS14320
uniprot id: A0A8D3Y2N2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS03325
gene id: 1123016:CL52_RS03325
uniprot id: A0A8D3XYM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1123016:CL52 RS03820
gene id: 1123016:CL52_RS03820
uniprot id: A0A8D3XYS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1123016:CL52 RS18830
gene id: 1123016:CL52_RS18830
uniprot id: A0A8D3Y528
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1123016:CL52 RS17170
gene id: 1123016:CL52_RS17170
uniprot id: A0A8D3Y3V0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1123016:CL52 RS12675
gene id: 1123016:CL52_RS12675
uniprot id: A0A8D4C7G5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1123016:CL52 RS01840
gene id: 1123016:CL52_RS01840
uniprot id: A0A8D4C007
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1123016:CL52 RS09130
gene id: 1123016:CL52_RS09130
uniprot id: A0A8D3Y0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS18570
gene id: 1123016:CL52_RS18570
uniprot id: A0A8D3Y469
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17445
gene id: 1123016:CL52_RS17445
uniprot id: A0A8D4C7X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1123016:CL52 RS02500
gene id: 1123016:CL52_RS02500
uniprot id: A0A8D3XYJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1123016:CL52 RS15815
gene id: 1123016:CL52_RS15815
uniprot id: A0A8D3Y3B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1123016:CL52 RS06340
gene id: 1123016:CL52_RS06340
uniprot id: A0A8D3XZY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1123016:CL52 RS15570
gene id: 1123016:CL52_RS15570
uniprot id: A0A8D4C7J7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1123016:CL52 RS15415
gene id: 1123016:CL52_RS15415
uniprot id: A0A8D4C2P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1123016:CL52 RS02770
gene id: 1123016:CL52_RS02770
uniprot id: A0A8D3XYU4
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1123016:CL52 RS04980
gene id: 1123016:CL52_RS04980
uniprot id: A0A8D4C1Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1123016:CL52 RS15505
gene id: 1123016:CL52_RS15505
uniprot id: A0A8D4C3U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1123016:CL52 RS12115
gene id: 1123016:CL52_RS12115
uniprot id: A0A8D4C348
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS05830
gene id: 1123016:CL52_RS05830
uniprot id: A0A8D4C250
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1123016:CL52 RS13850
gene id: 1123016:CL52_RS13850
uniprot id: A0A8D3Y2H0
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS01600
gene id: 1123016:CL52_RS01600
uniprot id: A0A8D4C4Z4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1123016:CL52 RS09690
gene id: 1123016:CL52_RS09690
uniprot id: A0A8D4C6Y7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS02485
gene id: 1123016:CL52_RS02485
uniprot id: A0A8D4C177
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1123016:CL52 RS17325
gene id: 1123016:CL52_RS17325
uniprot id: A0A8D3Y406
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1123016:CL52 RS13260
gene id: 1123016:CL52_RS13260
uniprot id: A0A8D3Y285
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1123016:CL52 RS12425
gene id: 1123016:CL52_RS12425
uniprot id: A0A8D3Y227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS15805
gene id: 1123016:CL52_RS15805
uniprot id: A0A8D3Y374
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1123016:CL52 RS10710
gene id: 1123016:CL52_RS10710
uniprot id: A0A8D4C1S1
names: Similarity
messages: Belongs to the transposase 8 family.

1123016:CL52 RS00770
gene id: 1123016:CL52_RS00770
uniprot id: A0A8D3XYI2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1123016:CL52 RS11200
gene id: 1123016:CL52_RS11200
uniprot id: A0A8D3Y1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS10985
gene id: 1123016:CL52_RS10985
uniprot id: A0A8D3Y1K2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123016:CL52 RS18245
gene id: 1123016:CL52_RS18245
uniprot id: A0A8D3Y3Z9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS02285
gene id: 1123016:CL52_RS02285
uniprot id: A0A8D4C1C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS03590
gene id: 1123016:CL52_RS03590
uniprot id: A0A8D4C5C4
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS01560
gene id: 1123016:CL52_RS01560
uniprot id: A0A8D3XXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1123016:CL52 RS04655
gene id: 1123016:CL52_RS04655
uniprot id: A0A8D4C0K1
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1123016:CL52 RS02525
gene id: 1123016:CL52_RS02525
uniprot id: A0A8D3XYE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1123016:CL52 RS16940
gene id: 1123016:CL52_RS16940
uniprot id: A0A8D3Y3R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1123016:CL52 RS18290
gene id: 1123016:CL52_RS18290
uniprot id: A0A8D3Y408
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1123016:CL52 RS15160
gene id: 1123016:CL52_RS15160
uniprot id: A0A8D3Y3R5
names: Similarity
messages: Belongs to the threonine synthase family.

1123016:CL52 RS01900
gene id: 1123016:CL52_RS01900
uniprot id: A0A8D3XYC0
names: Similarity
messages: Belongs to the universal stress protein A family.

1123016:CL52 RS06640
gene id: 1123016:CL52_RS06640
uniprot id: A0A8D3Y051
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1123016:CL52 RS09525
gene id: 1123016:CL52_RS09525
uniprot id: A0A8D3Y139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS04005
gene id: 1123016:CL52_RS04005
uniprot id: A0A8D3XZT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS13695
gene id: 1123016:CL52_RS13695
uniprot id: A0A8D4C3G1
names: Similarity
messages: Belongs to the WrbA family.

1123016:CL52 RS13545
gene id: 1123016:CL52_RS13545
uniprot id: A0A8D3Y2G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1123016:CL52 RS08545
gene id: 1123016:CL52_RS08545
uniprot id: A0A8D4C6R9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS13525
gene id: 1123016:CL52_RS13525
uniprot id: A0A8D4C2B4
names: Subcellular Location Annotation
messages: Cytoplasm

1123016:CL52 RS09145
gene id: 1123016:CL52_RS09145
uniprot id: A0A8D4C1F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1123016:CL52 RS19020
gene id: 1123016:CL52_RS19020
uniprot id: A0A8D3Y4C9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS06580
gene id: 1123016:CL52_RS06580
uniprot id: A0A8D3Y0C6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1123016:CL52 RS18075
gene id: 1123016:CL52_RS18075
uniprot id: A0A8D3Y435
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1123016:CL52 RS06475
gene id: 1123016:CL52_RS06475
uniprot id: A0A8D3XZQ2
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS18140
gene id: 1123016:CL52_RS18140
uniprot id: A0A8D3Y4U9
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS05010
gene id: 1123016:CL52_RS05010
uniprot id: A0A8D4C1R9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1123016:CL52 RS06490
gene id: 1123016:CL52_RS06490
uniprot id: A0A8D3Y093
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS11260
gene id: 1123016:CL52_RS11260
uniprot id: A0A8D3Y1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS15625
gene id: 1123016:CL52_RS15625
uniprot id: A0A8D3Y3B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1123016:CL52 RS18510
gene id: 1123016:CL52_RS18510
uniprot id: A0A8D3Y4W6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1123016:CL52 RS12180
gene id: 1123016:CL52_RS12180
uniprot id: A0A8D4C6X1
names: Similarity
messages: Belongs to the MotB family.

1123016:CL52 RS13330
gene id: 1123016:CL52_RS13330
uniprot id: A0A8D4C7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1123016:CL52 RS02820
gene id: 1123016:CL52_RS02820
uniprot id: A0A8D3XYG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1123016:CL52 RS07330
gene id: 1123016:CL52_RS07330
uniprot id: A0A8D4C125
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1123016:CL52 RS07655
gene id: 1123016:CL52_RS07655
uniprot id: A0A8D3Y0F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS02790
gene id: 1123016:CL52_RS02790
uniprot id: A0A8D3XYF7
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1123016:CL52 RS13410
gene id: 1123016:CL52_RS13410
uniprot id: A0A8D3Y2G4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1123016:CL52 RS08010
gene id: 1123016:CL52_RS08010
uniprot id: A0A8D4C6N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1123016:CL52 RS15155
gene id: 1123016:CL52_RS15155
uniprot id: A0A8D3Y2X8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1123016:CL52 RS17995
gene id: 1123016:CL52_RS17995
uniprot id: A0A8D4C8E7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1123016:CL52 RS08405
gene id: 1123016:CL52_RS08405
uniprot id: A0A8D3Y0Q0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1123016:CL52 RS09240
gene id: 1123016:CL52_RS09240
uniprot id: A0A8D4C2L8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS19445
gene id: 1123016:CL52_RS19445
uniprot id: A0A8D3Y591
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1123016:CL52 RS17450
gene id: 1123016:CL52_RS17450
uniprot id: A0A8D3Y3S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1123016:CL52 RS20005
gene id: 1123016:CL52_RS20005
uniprot id: A0A8D3Y4Y2
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

1123016:CL52 RS02335
gene id: 1123016:CL52_RS02335
uniprot id: A0A8D3XY98
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1123016:CL52 RS03555
gene id: 1123016:CL52_RS03555
uniprot id: A0A8D3XZM7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1123016:CL52 RS08065
gene id: 1123016:CL52_RS08065
uniprot id: A0A8D3Y0I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1123016:CL52 RS09300
gene id: 1123016:CL52_RS09300
uniprot id: A0A8D4C1G8
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS01350
gene id: 1123016:CL52_RS01350
uniprot id: A0A8D3XXZ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS19700
gene id: 1123016:CL52_RS19700
uniprot id: A0A8D4C8R1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1123016:CL52 RS12545
gene id: 1123016:CL52_RS12545
uniprot id: A0A8D4C238
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1123016:CL52 RS13380
gene id: 1123016:CL52_RS13380
uniprot id: A0A8D3Y2W4
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1123016:CL52 RS10550
gene id: 1123016:CL52_RS10550
uniprot id: A0A8D3Y194
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1123016:CL52 RS05845
gene id: 1123016:CL52_RS05845
uniprot id: A0A8D4C5S2
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS05015
gene id: 1123016:CL52_RS05015
uniprot id: A0A8D3XZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1123016:CL52 RS18965
gene id: 1123016:CL52_RS18965
uniprot id: A0A8D3Y4I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1123016:CL52 RS11920
gene id: 1123016:CL52_RS11920
uniprot id: A0A8D3Y1Z6
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS19510
gene id: 1123016:CL52_RS19510
uniprot id: A0A8D4C4T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1123016:CL52 RS03875
gene id: 1123016:CL52_RS03875
uniprot id: A0A8D4C1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1123016:CL52 RS17465
gene id: 1123016:CL52_RS17465
uniprot id: A0A8D3Y4I4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS04700
gene id: 1123016:CL52_RS04700
uniprot id: A0A8D3Y013
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1123016:CL52 RS08625
gene id: 1123016:CL52_RS08625
uniprot id: A0A8D3Y0M3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1123016:CL52 RS18785
gene id: 1123016:CL52_RS18785
uniprot id: A0A8D4C3E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1123016:CL52 RS07685
gene id: 1123016:CL52_RS07685
uniprot id: A0A8D4C6L6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1123016:CL52 RS09330
gene id: 1123016:CL52_RS09330
uniprot id: A0A8D3Y0Z7
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1123016:CL52 RS05975
gene id: 1123016:CL52_RS05975
uniprot id: A0A8D3XZS5
names: Similarity
messages: Belongs to the YfgM family.

1123016:CL52 RS10600
gene id: 1123016:CL52_RS10600
uniprot id: A0A8D3Y246
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS16805
gene id: 1123016:CL52_RS16805
uniprot id: A0A8D3Y4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1123016:CL52 RS19505
gene id: 1123016:CL52_RS19505
uniprot id: A0A8D3Y4H6
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1123016:CL52 RS07855
gene id: 1123016:CL52_RS07855
uniprot id: A0A8D3Y168
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS10055
gene id: 1123016:CL52_RS10055
uniprot id: A0A8D3Y172
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1123016:CL52 RS17845
gene id: 1123016:CL52_RS17845
uniprot id: A0A8D4C8D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1123016:CL52 RS01440
gene id: 1123016:CL52_RS01440
uniprot id: A0A8D3XXY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS01345
gene id: 1123016:CL52_RS01345
uniprot id: A0A8D4C5H7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS06105
gene id: 1123016:CL52_RS06105
uniprot id: A0A8D3Y072
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1123016:CL52 RS18180
gene id: 1123016:CL52_RS18180
uniprot id: A0A8D4C823
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

1123016:CL52 RS14240
gene id: 1123016:CL52_RS14240
uniprot id: A0A8D3Y2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS12650
gene id: 1123016:CL52_RS12650
uniprot id: A0A8D3Y2L9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS16975
gene id: 1123016:CL52_RS16975
uniprot id: A0A8D4C4N9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1123016:CL52 RS04125
gene id: 1123016:CL52_RS04125
uniprot id: A0A8D4C1K6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS17690
gene id: 1123016:CL52_RS17690
uniprot id: A0A8D3Y4N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1123016:CL52 RS20285
gene id: 1123016:CL52_RS20285
uniprot id: A0A8D3Y4R4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS07205
gene id: 1123016:CL52_RS07205
uniprot id: A0A8D3Y079
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1123016:CL52 RS06840
gene id: 1123016:CL52_RS06840
uniprot id: A0A8D3Y0T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1123016:CL52 RS11735
gene id: 1123016:CL52_RS11735
uniprot id: A0A8D3Y1W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1123016:CL52 RS08230
gene id: 1123016:CL52_RS08230
uniprot id: A0A8D3Y0X7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS05390
gene id: 1123016:CL52_RS05390
uniprot id: A0A8D4C5P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1123016:CL52 RS13715
gene id: 1123016:CL52_RS13715
uniprot id: A0A8D3Y2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1123016:CL52 RS09930
gene id: 1123016:CL52_RS09930
uniprot id: A0A8D4C314
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS15795
gene id: 1123016:CL52_RS15795
uniprot id: A0A8D4C2S4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1123016:CL52 RS18200
gene id: 1123016:CL52_RS18200
uniprot id: A0A8D3Y4S1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1123016:CL52 RS00825
gene id: 1123016:CL52_RS00825
uniprot id: A0A8D4C114
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS17260
gene id: 1123016:CL52_RS17260
uniprot id: A0A8D3Y4J1
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17810
gene id: 1123016:CL52_RS17810
uniprot id: A0A8D4C4B7
names: Similarity
messages: Belongs to the PhoH family.

1123016:CL52 RS08755
gene id: 1123016:CL52_RS08755
uniprot id: A0A8D4C6A9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1123016:CL52 RS12130
gene id: 1123016:CL52_RS12130
uniprot id: A0A8D3Y1Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1123016:CL52 RS05840
gene id: 1123016:CL52_RS05840
uniprot id: A0A8D4C0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1123016:CL52 RS08660
gene id: 1123016:CL52_RS08660
uniprot id: A0A8D3Y0N1
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS03830
gene id: 1123016:CL52_RS03830
uniprot id: A0A8D3XZ48
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1123016:CL52 RS19740
gene id: 1123016:CL52_RS19740
uniprot id: A0A8D4C4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS17880
gene id: 1123016:CL52_RS17880
uniprot id: A0A8D3Y3X0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1123016:CL52 RS03270
gene id: 1123016:CL52_RS03270
uniprot id: A0A8D4C1D3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123016:CL52 RS13110
gene id: 1123016:CL52_RS13110
uniprot id: A0A8D3Y2B5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS20000
gene id: 1123016:CL52_RS20000
uniprot id: A0A8D3Y4Y1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

1123016:CL52 RS01530
gene id: 1123016:CL52_RS01530
uniprot id: A0A8D3XY05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS15080
gene id: 1123016:CL52_RS15080
uniprot id: A0A8D3Y2W8
names: Similarity
messages: Belongs to the leucine-binding protein family.

1123016:CL52 RS06540
gene id: 1123016:CL52_RS06540
uniprot id: A0A8D3XZX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1123016:CL52 RS09160
gene id: 1123016:CL52_RS09160
uniprot id: A0A8D4C2L1
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

1123016:CL52 RS16380
gene id: 1123016:CL52_RS16380
uniprot id: A0A8D3Y3J3
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1123016:CL52 RS14395
gene id: 1123016:CL52_RS14395
uniprot id: A0A8D4C2H8
names: Similarity
messages: Belongs to the DapA family.

1123016:CL52 RS04780
gene id: 1123016:CL52_RS04780
uniprot id: A0A8D3XZM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS15970
gene id: 1123016:CL52_RS15970
uniprot id: A0A8D3Y3E9
names: Similarity
messages: Belongs to the peptidase U62 family.

1123016:CL52 RS03500
gene id: 1123016:CL52_RS03500
uniprot id: A0A8D4C1L9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1123016:CL52 RS15255
gene id: 1123016:CL52_RS15255
uniprot id: A0A8D4C468
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS12790
gene id: 1123016:CL52_RS12790
uniprot id: A0A8D3Y235
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1123016:CL52 RS19365
gene id: 1123016:CL52_RS19365
uniprot id: A0A8D3Y4L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1123016:CL52 RS15125
gene id: 1123016:CL52_RS15125
uniprot id: A0A8D3Y2Y2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1123016:CL52 RS07040
gene id: 1123016:CL52_RS07040
uniprot id: A0A8D3Y097
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1123016:CL52 RS10950
gene id: 1123016:CL52_RS10950
uniprot id: A0A8D4C1T9
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS05085
gene id: 1123016:CL52_RS05085
uniprot id: A0A8D4C5L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1123016:CL52 RS01860
gene id: 1123016:CL52_RS01860
uniprot id: A0A8D3XYJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1123016:CL52 RS11220
gene id: 1123016:CL52_RS11220
uniprot id: A0A8D3Y1M7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1123016:CL52 RS00180
gene id: 1123016:CL52_RS00180
uniprot id: A0A8D4C0X9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1123016:CL52 RS19390
gene id: 1123016:CL52_RS19390
uniprot id: A0A8D3Y594
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1123016:CL52 RS03385
gene id: 1123016:CL52_RS03385
uniprot id: A0A8D3XZK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1123016:CL52 RS00890
gene id: 1123016:CL52_RS00890
uniprot id: A0A8D3XXT4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS12835
gene id: 1123016:CL52_RS12835
uniprot id: A0A8D3Y295
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS02860
gene id: 1123016:CL52_RS02860
uniprot id: A0A8D3XZ68
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1123016:CL52 RS02780
gene id: 1123016:CL52_RS02780
uniprot id: A0A8D3XYN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1123016:CL52 RS09375
gene id: 1123016:CL52_RS09375
uniprot id: A0A8D4C2Y0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1123016:CL52 RS01365
gene id: 1123016:CL52_RS01365
uniprot id: A0A8D3XXX4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1123016:CL52 RS04575
gene id: 1123016:CL52_RS04575
uniprot id: A0A8D3XZ56
names: Similarity
messages: Belongs to the GARS family.

1123016:CL52 RS07135
gene id: 1123016:CL52_RS07135
uniprot id: A0A8D3Y025
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1123016:CL52 RS03920
gene id: 1123016:CL52_RS03920
uniprot id: A0A8D3XZH9
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS15850
gene id: 1123016:CL52_RS15850
uniprot id: A0A8D4C816
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1123016:CL52 RS12670
gene id: 1123016:CL52_RS12670
uniprot id: A0A8D3Y2W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1123016:CL52 RS01815
gene id: 1123016:CL52_RS01815
uniprot id: A0A8D4C5L0
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

1123016:CL52 RS17105
gene id: 1123016:CL52_RS17105
uniprot id: A0A8D3Y3L2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1123016:CL52 RS09350
gene id: 1123016:CL52_RS09350
uniprot id: A0A8D3Y0V9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1123016:CL52 RS12680
gene id: 1123016:CL52_RS12680
uniprot id: A0A8D3Y276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1123016:CL52 RS03810
gene id: 1123016:CL52_RS03810
uniprot id: A0A8D4C0D2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1123016:CL52 RS07305
gene id: 1123016:CL52_RS07305
uniprot id: A0A8D4C6J0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1123016:CL52 RS19770
gene id: 1123016:CL52_RS19770
uniprot id: A0A8D3Y5D1
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1123016:CL52 RS03465
gene id: 1123016:CL52_RS03465
uniprot id: A0A8D4C5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1123016:CL52 RS15040
gene id: 1123016:CL52_RS15040
uniprot id: A0A8D4C2L9
names: Similarity
messages: Belongs to the RseA family.

1123016:CL52 RS08300
gene id: 1123016:CL52_RS08300
uniprot id: A0A8D3Y0L5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1123016:CL52 RS08945
gene id: 1123016:CL52_RS08945
uniprot id: A0A8D3Y1A8
names: Subunit
messages: Monomer. Interacts with PqqE.

1123016:CL52 RS03305
gene id: 1123016:CL52_RS03305
uniprot id: A0A8D4C5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1123016:CL52 RS02480
gene id: 1123016:CL52_RS02480
uniprot id: A0A8D3XYC4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1123016:CL52 RS02090
gene id: 1123016:CL52_RS02090
uniprot id: A0A8D3XYL7
names: Similarity
messages: Belongs to the YicC/YloC family.

1123016:CL52 RS06330
gene id: 1123016:CL52_RS06330
uniprot id: A0A8D3Y009
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS07315
gene id: 1123016:CL52_RS07315
uniprot id: A0A8D3Y0B8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS02135
gene id: 1123016:CL52_RS02135
uniprot id: A0A8D3XY77
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1123016:CL52 RS04540
gene id: 1123016:CL52_RS04540
uniprot id: A0A8D3XZ32
names: Similarity
messages: Belongs to the SfsA family.

1123016:CL52 RS08305
gene id: 1123016:CL52_RS08305
uniprot id: A0A8D3Y0Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1123016:CL52 RS17165
gene id: 1123016:CL52_RS17165
uniprot id: A0A8D3Y4E2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1123016:CL52 RS15800
gene id: 1123016:CL52_RS15800
uniprot id: A0A8D4C7L2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1123016:CL52 RS12715
gene id: 1123016:CL52_RS12715
uniprot id: A0A8D4C389
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1123016:CL52 RS06405
gene id: 1123016:CL52_RS06405
uniprot id: A0A8D4C214
names: Subcellular Location Annotation
messages: Cytoplasm

1123016:CL52 RS14010
gene id: 1123016:CL52_RS14010
uniprot id: A0A8D3Y2M4
names: Similarity
messages: Belongs to the OprB family.

1123016:CL52 RS09665
gene id: 1123016:CL52_RS09665
uniprot id: A0A8D3Y133
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS07390
gene id: 1123016:CL52_RS07390
uniprot id: A0A8D3Y0C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS11945
gene id: 1123016:CL52_RS11945
uniprot id: A0A8D3Y1S1
names: Similarity
messages: Belongs to the MotB family.

1123016:CL52 RS16965
gene id: 1123016:CL52_RS16965
uniprot id: A0A8D3Y3Q1
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1123016:CL52 RS00280
gene id: 1123016:CL52_RS00280
uniprot id: A0A8D4C0T2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1123016:CL52 RS08075
gene id: 1123016:CL52_RS08075
uniprot id: A0A8D3Y0E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS19885
gene id: 1123016:CL52_RS19885
uniprot id: A0A8D3Y4L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123016:CL52 RS01970
gene id: 1123016:CL52_RS01970
uniprot id: A0A8D3XY76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123016:CL52 RS01915
gene id: 1123016:CL52_RS01915
uniprot id: A0A8D4C012
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17640
gene id: 1123016:CL52_RS17640
uniprot id: A0A8D3Y3S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1123016:CL52 RS01220
gene id: 1123016:CL52_RS01220
uniprot id: A0A8D4BZW1
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1123016:CL52 RS00360
gene id: 1123016:CL52_RS00360
uniprot id: A0A8D3XXI4
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17915
gene id: 1123016:CL52_RS17915
uniprot id: A0A8D3Y4R8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1123016:CL52 RS05880
gene id: 1123016:CL52_RS05880
uniprot id: A0A8D3Y044
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1123016:CL52 RS18235
gene id: 1123016:CL52_RS18235
uniprot id: A0A8D3Y4A7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS20235
gene id: 1123016:CL52_RS20235
uniprot id: A0A8D3Y4Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1123016:CL52 RS11685
gene id: 1123016:CL52_RS11685
uniprot id: A0A8D3Y1P5
names: Similarity
messages: Belongs to the peptidase A24 family.

1123016:CL52 RS17360
gene id: 1123016:CL52_RS17360
uniprot id: A0A8D3Y3P6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1123016:CL52 RS08635
gene id: 1123016:CL52_RS08635
uniprot id: A0A8D4C6S5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS18110
gene id: 1123016:CL52_RS18110
uniprot id: A0A8D4C4F5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1123016:CL52 RS08145
gene id: 1123016:CL52_RS08145
uniprot id: A0A8D3Y0Z8
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1123016:CL52 RS18745
gene id: 1123016:CL52_RS18745
uniprot id: A0A8D3Y4H8
names: Similarity
messages: Belongs to the GSP E family.

1123016:CL52 RS11310
gene id: 1123016:CL52_RS11310
uniprot id: A0A8D3Y2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1123016:CL52 RS05745
gene id: 1123016:CL52_RS05745
uniprot id: A0A8D3XZP2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1123016:CL52 RS16035
gene id: 1123016:CL52_RS16035
uniprot id: A0A8D3Y3A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1123016:CL52 RS16840
gene id: 1123016:CL52_RS16840
uniprot id: A0A8D4C7T2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1123016:CL52 RS05480
gene id: 1123016:CL52_RS05480
uniprot id: A0A8D3XZP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS02290
gene id: 1123016:CL52_RS02290
uniprot id: A0A8D3XYA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS10025
gene id: 1123016:CL52_RS10025
uniprot id: A0A8D3Y136
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1123016:CL52 RS03520
gene id: 1123016:CL52_RS03520
uniprot id: A0A8D3XYN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1123016:CL52 RS20145
gene id: 1123016:CL52_RS20145
uniprot id: A0A8D3Y4X5
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS14335
gene id: 1123016:CL52_RS14335
uniprot id: A0A8D3Y383
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1123016:CL52 RS03330
gene id: 1123016:CL52_RS03330
uniprot id: A0A8D4C0A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1123016:CL52 RS02420
gene id: 1123016:CL52_RS02420
uniprot id: A0A8D3XYI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1123016:CL52 RS18740
gene id: 1123016:CL52_RS18740
uniprot id: A0A8D3Y4G4
names: Similarity
messages: Belongs to the GSP E family.

1123016:CL52 RS01390
gene id: 1123016:CL52_RS01390
uniprot id: A0A8D3XYD4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1123016:CL52 RS18645
gene id: 1123016:CL52_RS18645
uniprot id: A0A8D3Y477
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1123016:CL52 RS08135
gene id: 1123016:CL52_RS08135
uniprot id: A0A8D4C2D8
names: Similarity
messages: Belongs to the citrate synthase family.

1123016:CL52 RS05155
gene id: 1123016:CL52_RS05155
uniprot id: A0A8D4C0N7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1123016:CL52 RS17295
gene id: 1123016:CL52_RS17295
uniprot id: A0A8D4C7W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1123016:CL52 RS06930
gene id: 1123016:CL52_RS06930
uniprot id: A0A8D3Y067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS12740
gene id: 1123016:CL52_RS12740
uniprot id: A0A8D3Y229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1123016:CL52 RS01930
gene id: 1123016:CL52_RS01930
uniprot id: A0A8D4C138
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1123016:CL52 RS07895
gene id: 1123016:CL52_RS07895
uniprot id: A0A8D3Y094
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS03545
gene id: 1123016:CL52_RS03545
uniprot id: A0A8D3XZU1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1123016:CL52 RS10655
gene id: 1123016:CL52_RS10655
uniprot id: A0A8D3Y1W9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1123016:CL52 RS01370
gene id: 1123016:CL52_RS01370
uniprot id: A0A8D4BZX2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123016:CL52 RS08765
gene id: 1123016:CL52_RS08765
uniprot id: A0A8D4C2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS00270
gene id: 1123016:CL52_RS00270
uniprot id: A0A8D4C4P2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1123016:CL52 RS15050
gene id: 1123016:CL52_RS15050
uniprot id: A0A8D3Y2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1123016:CL52 RS10105
gene id: 1123016:CL52_RS10105
uniprot id: A0A8D3Y145
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1123016:CL52 RS20220
gene id: 1123016:CL52_RS20220
uniprot id: A0A8D4C8F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1123016:CL52 RS09480
gene id: 1123016:CL52_RS09480
uniprot id: A0A8D4C2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1123016:CL52 RS11630
gene id: 1123016:CL52_RS11630
uniprot id: A0A8D3Y1S9
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS15315
gene id: 1123016:CL52_RS15315
uniprot id: A0A8D4C7X5
names: Similarity
messages: Belongs to the UPF0246 family.

1123016:CL52 RS12190
gene id: 1123016:CL52_RS12190
uniprot id: A0A8D4C353
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1123016:CL52 RS05385
gene id: 1123016:CL52_RS05385
uniprot id: A0A8D4C0Q3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS00820
gene id: 1123016:CL52_RS00820
uniprot id: A0A8D3XXX3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1123016:CL52 RS09825
gene id: 1123016:CL52_RS09825
uniprot id: A0A8D3Y1G8
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1123016:CL52 RS07435
gene id: 1123016:CL52_RS07435
uniprot id: A0A8D3Y0B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1123016:CL52 RS10990
gene id: 1123016:CL52_RS10990
uniprot id: A0A8D3Y1V1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1123016:CL52 RS17850
gene id: 1123016:CL52_RS17850
uniprot id: A0A8D3Y407
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1123016:CL52 RS15790
gene id: 1123016:CL52_RS15790
uniprot id: A0A8D3Y360
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1123016:CL52 RS05455
gene id: 1123016:CL52_RS05455
uniprot id: A0A8D3XZI9
names: Similarity
messages: Belongs to the allantoicase family.

1123016:CL52 RS14300
gene id: 1123016:CL52_RS14300
uniprot id: A0A8D4C3Z6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS07145
gene id: 1123016:CL52_RS07145
uniprot id: A0A8D4C6H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1123016:CL52 RS07030
gene id: 1123016:CL52_RS07030
uniprot id: A0A8D3XZX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1123016:CL52 RS11755
gene id: 1123016:CL52_RS11755
uniprot id: A0A8D4C1Y8
names: Similarity
messages: Belongs to the LEA type 2 family.

1123016:CL52 RS04840
gene id: 1123016:CL52_RS04840
uniprot id: A0A8D4C5K3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1123016:CL52 RS07800
gene id: 1123016:CL52_RS07800
uniprot id: A0A8D4C2L3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1123016:CL52 RS02385
gene id: 1123016:CL52_RS02385
uniprot id: A0A8D3XYB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1123016:CL52 RS02055
gene id: 1123016:CL52_RS02055
uniprot id: A0A8D4C1A6
names: Similarity
messages: Belongs to the RutC family.

1123016:CL52 RS12730
gene id: 1123016:CL52_RS12730
uniprot id: A0A8D3Y269
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1123016:CL52 RS14435
gene id: 1123016:CL52_RS14435
uniprot id: A0A8D3Y316
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1123016:CL52 RS18205
gene id: 1123016:CL52_RS18205
uniprot id: A0A8D3Y493
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1123016:CL52 RS05530
gene id: 1123016:CL52_RS05530
uniprot id: A0A8D3XZK1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS09905
gene id: 1123016:CL52_RS09905
uniprot id: A0A8D3Y119
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS11225
gene id: 1123016:CL52_RS11225
uniprot id: A0A8D3Y1Y1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS08960
gene id: 1123016:CL52_RS08960
uniprot id: A0A8D3Y0R8
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1123016:CL52 RS19960
gene id: 1123016:CL52_RS19960
uniprot id: A0A8D4C5A7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS07405
gene id: 1123016:CL52_RS07405
uniprot id: A0A8D4C129
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

1123016:CL52 RS02225
gene id: 1123016:CL52_RS02225
uniprot id: A0A8D3XY88
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1123016:CL52 RS08965
gene id: 1123016:CL52_RS08965
uniprot id: A0A8D3Y1K7
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1123016:CL52 RS00410
gene id: 1123016:CL52_RS00410
uniprot id: A0A8D3XXS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1123016:CL52 RS18210
gene id: 1123016:CL52_RS18210
uniprot id: A0A8D3Y4A5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1123016:CL52 RS11215
gene id: 1123016:CL52_RS11215
uniprot id: A0A8D3Y239
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1123016:CL52 RS01400
gene id: 1123016:CL52_RS01400
uniprot id: A0A8D3XY48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS04590
gene id: 1123016:CL52_RS04590
uniprot id: A0A8D3XZ24
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1123016:CL52 RS17920
gene id: 1123016:CL52_RS17920
uniprot id: A0A8D4C8E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1123016:CL52 RS11930
gene id: 1123016:CL52_RS11930
uniprot id: A0A8D3Y1R6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1123016:CL52 RS11100
gene id: 1123016:CL52_RS11100
uniprot id: A0A8D4C395
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

1123016:CL52 RS02610
gene id: 1123016:CL52_RS02610
uniprot id: A0A8D3XYM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS15195
gene id: 1123016:CL52_RS15195
uniprot id: A0A8D4C7G9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1123016:CL52 RS18255
gene id: 1123016:CL52_RS18255
uniprot id: A0A8D4C828
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS07775
gene id: 1123016:CL52_RS07775
uniprot id: A0A8D3Y0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1123016:CL52 RS18750
gene id: 1123016:CL52_RS18750
uniprot id: A0A8D3Y473
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1123016:CL52 RS10150
gene id: 1123016:CL52_RS10150
uniprot id: A0A8D3Y1K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1123016:CL52 RS03215
gene id: 1123016:CL52_RS03215
uniprot id: A0A8D3XYK8
names: Similarity
messages: Belongs to the CapA family.

1123016:CL52 RS08540
gene id: 1123016:CL52_RS08540
uniprot id: A0A8D3Y1F7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123016:CL52 RS04365
gene id: 1123016:CL52_RS04365
uniprot id: A0A8D3XZ69
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1123016:CL52 RS03345
gene id: 1123016:CL52_RS03345
uniprot id: A0A8D4C1E1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1123016:CL52 RS19855
gene id: 1123016:CL52_RS19855
uniprot id: A0A8D3Y4L8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1123016:CL52 RS01415
gene id: 1123016:CL52_RS01415
uniprot id: A0A8D3XYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1123016:CL52 RS09225
gene id: 1123016:CL52_RS09225
uniprot id: A0A8D4C1G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123016:CL52 RS15735
gene id: 1123016:CL52_RS15735
uniprot id: A0A8D3Y3A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1123016:CL52 RS06965
gene id: 1123016:CL52_RS06965
uniprot id: A0A8D3Y091
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1123016:CL52 RS07035
gene id: 1123016:CL52_RS07035
uniprot id: A0A8D4C254
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1123016:CL52 RS07400
gene id: 1123016:CL52_RS07400
uniprot id: A0A8D3Y086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1123016:CL52 RS05290
gene id: 1123016:CL52_RS05290
uniprot id: A0A8D3XZI3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1123016:CL52 RS20160
gene id: 1123016:CL52_RS20160
uniprot id: A0A8D3Y500
names: Similarity
messages: Belongs to the thioredoxin family.

1123016:CL52 RS02785
gene id: 1123016:CL52_RS02785
uniprot id: A0A8D3XZ61
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1123016:CL52 RS13730
gene id: 1123016:CL52_RS13730
uniprot id: A0A8D4C7M7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1123016:CL52 RS03415
gene id: 1123016:CL52_RS03415
uniprot id: A0A8D4C0A7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1123016:CL52 RS13405
gene id: 1123016:CL52_RS13405
uniprot id: A0A8D4C7K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1123016:CL52 RS18320
gene id: 1123016:CL52_RS18320
uniprot id: A0A8D3Y409
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1123016:CL52 RS03505
gene id: 1123016:CL52_RS03505
uniprot id: A0A8D3XYP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS15265
gene id: 1123016:CL52_RS15265
uniprot id: A0A8D4C2N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS14380
gene id: 1123016:CL52_RS14380
uniprot id: A0A8D3Y2V1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS02475
gene id: 1123016:CL52_RS02475
uniprot id: A0A8D4C560
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1123016:CL52 RS09915
gene id: 1123016:CL52_RS09915
uniprot id: A0A8D4C700
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1123016:CL52 RS18895
gene id: 1123016:CL52_RS18895
uniprot id: A0A8D3Y4J5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123016:CL52 RS04285
gene id: 1123016:CL52_RS04285
uniprot id: A0A8D3XZG5
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS00860
gene id: 1123016:CL52_RS00860
uniprot id: A0A8D3XY64
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123016:CL52 RS02040
gene id: 1123016:CL52_RS02040
uniprot id: A0A8D4C5M2
names: Similarity
messages: Belongs to the AAA ATPase family.

1123016:CL52 RS05320
gene id: 1123016:CL52_RS05320
uniprot id: A0A8D4C1T8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1123016:CL52 RS10545
gene id: 1123016:CL52_RS10545
uniprot id: A0A8D4C356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS12755
gene id: 1123016:CL52_RS12755
uniprot id: A0A8D3Y287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1123016:CL52 RS19440
gene id: 1123016:CL52_RS19440
uniprot id: A0A8D3Y4N2
names: Similarity
messages: Belongs to the asparaginase 1 family.

1123016:CL52 RS01925
gene id: 1123016:CL52_RS01925
uniprot id: A0A8D3XY49
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1123016:CL52 RS04690
gene id: 1123016:CL52_RS04690
uniprot id: A0A8D3XZR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1123016:CL52 RS03580
gene id: 1123016:CL52_RS03580
uniprot id: A0A8D3XYQ4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1123016:CL52 RS08210
gene id: 1123016:CL52_RS08210
uniprot id: A0A8D4C2E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1123016:CL52 RS09935
gene id: 1123016:CL52_RS09935
uniprot id: A0A8D3Y128
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1123016:CL52 RS18860
gene id: 1123016:CL52_RS18860
uniprot id: A0A8D4C3E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1123016:CL52 RS09535
gene id: 1123016:CL52_RS09535
uniprot id: A0A8D4C2Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1123016:CL52 RS00025
gene id: 1123016:CL52_RS00025
uniprot id: A0A8D3XXH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1123016:CL52 RS10925
gene id: 1123016:CL52_RS10925
uniprot id: A0A8D3Y1K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1123016:CL52 RS03575
gene id: 1123016:CL52_RS03575
uniprot id: A0A8D4C1N1
names: Similarity
messages: Belongs to the histone deacetylase family.

1123016:CL52 RS18390
gene id: 1123016:CL52_RS18390
uniprot id: A0A8D3Y4D4
names: Subcellular Location Annotation
messages: Cytoplasm

1123016:CL52 RS03175
gene id: 1123016:CL52_RS03175
uniprot id: A0A8D4C091
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1123016:CL52 RS08730
gene id: 1123016:CL52_RS08730
uniprot id: A0A8D3Y0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1123016:CL52 RS08950
gene id: 1123016:CL52_RS08950
uniprot id: A0A8D3Y0U4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123016:CL52 RS05900
gene id: 1123016:CL52_RS05900
uniprot id: A0A8D3XZR8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1123016:CL52 RS08640
gene id: 1123016:CL52_RS08640
uniprot id: A0A8D3Y0S7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1123016:CL52 RS04815
gene id: 1123016:CL52_RS04815
uniprot id: A0A8D3XZB8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1123016:CL52 RS16835
gene id: 1123016:CL52_RS16835
uniprot id: A0A8D4C301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1123016:CL52 RS10485
gene id: 1123016:CL52_RS10485
uniprot id: A0A8D4C6L5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS02125
gene id: 1123016:CL52_RS02125
uniprot id: A0A8D3XYF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1123016:CL52 RS07480
gene id: 1123016:CL52_RS07480
uniprot id: A0A8D4C136
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1123016:CL52 RS09295
gene id: 1123016:CL52_RS09295
uniprot id: A0A8D3Y0U8
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1123016:CL52 RS08160
gene id: 1123016:CL52_RS08160
uniprot id: A0A8D3Y0F9
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1123016:CL52 RS08715
gene id: 1123016:CL52_RS08715
uniprot id: A0A8D3Y1H9
names: Similarity
messages: Belongs to the carbamate kinase family.

1123016:CL52 RS07600
gene id: 1123016:CL52_RS07600
uniprot id: A0A8D3Y098
names: Similarity
messages: Belongs to the YciI family.

1123016:CL52 RS02965
gene id: 1123016:CL52_RS02965
uniprot id: A0A8D3XZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1123016:CL52 RS19370
gene id: 1123016:CL52_RS19370
uniprot id: A0A8D3Y581
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1123016:CL52 RS07860
gene id: 1123016:CL52_RS07860
uniprot id: A0A8D4C6M8
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17335
gene id: 1123016:CL52_RS17335
uniprot id: A0A8D3Y4J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1123016:CL52 RS07060
gene id: 1123016:CL52_RS07060
uniprot id: A0A8D3Y016
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1123016:CL52 RS12940
gene id: 1123016:CL52_RS12940
uniprot id: A0A8D3Y256
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1123016:CL52 RS15880
gene id: 1123016:CL52_RS15880
uniprot id: A0A8D4C7M1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS07565
gene id: 1123016:CL52_RS07565
uniprot id: A0A8D4C635
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1123016:CL52 RS00455
gene id: 1123016:CL52_RS00455
uniprot id: A0A8D3XXQ4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1123016:CL52 RS03365
gene id: 1123016:CL52_RS03365
uniprot id: A0A8D3XZ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1123016:CL52 RS00560
gene id: 1123016:CL52_RS00560
uniprot id: A0A8D3XXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1123016:CL52 RS06535
gene id: 1123016:CL52_RS06535
uniprot id: A0A8D4C2B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS05185
gene id: 1123016:CL52_RS05185
uniprot id: A0A8D3XZG9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1123016:CL52 RS03985
gene id: 1123016:CL52_RS03985
uniprot id: A0A8D3XZB7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1123016:CL52 RS14205
gene id: 1123016:CL52_RS14205
uniprot id: A0A8D3Y2S7
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS03620
gene id: 1123016:CL52_RS03620
uniprot id: A0A8D3XZD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1123016:CL52 RS02460
gene id: 1123016:CL52_RS02460
uniprot id: A0A8D3XYC6
names: Similarity
messages: Belongs to the UPF0178 family.

1123016:CL52 RS16880
gene id: 1123016:CL52_RS16880
uniprot id: A0A8D3Y4E1
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1123016:CL52 RS14145
gene id: 1123016:CL52_RS14145
uniprot id: A0A8D4C2F8
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

1123016:CL52 RS03350
gene id: 1123016:CL52_RS03350
uniprot id: A0A8D3XZ01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1123016:CL52 RS12965
gene id: 1123016:CL52_RS12965
uniprot id: A0A8D3Y2J6
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS19570
gene id: 1123016:CL52_RS19570
uniprot id: A0A8D4C3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1123016:CL52 RS12855
gene id: 1123016:CL52_RS12855
uniprot id: A0A8D4C263
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS09435
gene id: 1123016:CL52_RS09435
uniprot id: A0A8D3Y1R7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1123016:CL52 RS11725
gene id: 1123016:CL52_RS11725
uniprot id: A0A8D3Y2J0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS10995
gene id: 1123016:CL52_RS10995
uniprot id: A0A8D3Y1F1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1123016:CL52 RS11955
gene id: 1123016:CL52_RS11955
uniprot id: A0A8D3Y1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS14445
gene id: 1123016:CL52_RS14445
uniprot id: A0A8D3Y2P6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS14375
gene id: 1123016:CL52_RS14375
uniprot id: A0A8D3Y2T4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1123016:CL52 RS18705
gene id: 1123016:CL52_RS18705
uniprot id: A0A8D3Y463
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1123016:CL52 RS01990
gene id: 1123016:CL52_RS01990
uniprot id: A0A8D4C015
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

1123016:CL52 RS02730
gene id: 1123016:CL52_RS02730
uniprot id: A0A8D3XYH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1123016:CL52 RS09425
gene id: 1123016:CL52_RS09425
uniprot id: A0A8D3Y1B8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS08495
gene id: 1123016:CL52_RS08495
uniprot id: A0A8D4C1A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1123016:CL52 RS20265
gene id: 1123016:CL52_RS20265
uniprot id: A0A8D4C8U7
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1123016:CL52 RS05380
gene id: 1123016:CL52_RS05380
uniprot id: A0A8D3XZH5
names: Similarity
messages: Belongs to the TPP enzyme family.

1123016:CL52 RS15675
gene id: 1123016:CL52_RS15675
uniprot id: A0A8D3Y3G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1123016:CL52 RS18605
gene id: 1123016:CL52_RS18605
uniprot id: A0A8D3Y503
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1123016:CL52 RS06760
gene id: 1123016:CL52_RS06760
uniprot id: A0A8D3XZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1123016:CL52 RS18865
gene id: 1123016:CL52_RS18865
uniprot id: A0A8D4C866
names: Similarity
messages: Belongs to the peptidase M16 family.

1123016:CL52 RS09595
gene id: 1123016:CL52_RS09595
uniprot id: A0A8D3Y1T7
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1123016:CL52 RS05060
gene id: 1123016:CL52_RS05060
uniprot id: A0A8D3XZE9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1123016:CL52 RS03095
gene id: 1123016:CL52_RS03095
uniprot id: A0A8D3XYJ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS12575
gene id: 1123016:CL52_RS12575
uniprot id: A0A8D3Y245
names: Similarity
messages: Belongs to the universal stress protein A family.

1123016:CL52 RS01475
gene id: 1123016:CL52_RS01475
uniprot id: A0A8D3XY61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123016:CL52 RS03380
gene id: 1123016:CL52_RS03380
uniprot id: A0A8D3XYM5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1123016:CL52 RS12735
gene id: 1123016:CL52_RS12735
uniprot id: A0A8D3Y2H1
names: Similarity
messages: Belongs to the Skp family.

1123016:CL52 RS13760
gene id: 1123016:CL52_RS13760
uniprot id: A0A8D4C773
names: Similarity
messages: Belongs to the ArsC family.

1123016:CL52 RS01240
gene id: 1123016:CL52_RS01240
uniprot id: A0A8D3XYB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1123016:CL52 RS17345
gene id: 1123016:CL52_RS17345
uniprot id: A0A8D3Y3U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1123016:CL52 RS03995
gene id: 1123016:CL52_RS03995
uniprot id: A0A8D3XZI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1123016:CL52 RS17500
gene id: 1123016:CL52_RS17500
uniprot id: A0A8D3Y3R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS18520
gene id: 1123016:CL52_RS18520
uniprot id: A0A8D3Y4E3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS05730
gene id: 1123016:CL52_RS05730
uniprot id: A0A8D3XZH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1123016:CL52 RS01635
gene id: 1123016:CL52_RS01635
uniprot id: A0A8D3XY04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1123016:CL52 RS11720
gene id: 1123016:CL52_RS11720
uniprot id: A0A8D3Y1P1
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1123016:CL52 RS15980
gene id: 1123016:CL52_RS15980
uniprot id: A0A8D3Y3E3
names: Similarity
messages: Belongs to the peptidase U62 family.

1123016:CL52 RS12375
gene id: 1123016:CL52_RS12375
uniprot id: A0A8D3Y240
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1123016:CL52 RS11740
gene id: 1123016:CL52_RS11740
uniprot id: A0A8D3Y1X4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1123016:CL52 RS01195
gene id: 1123016:CL52_RS01195
uniprot id: A0A8D4C5G4
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1123016:CL52 RS01385
gene id: 1123016:CL52_RS01385
uniprot id: A0A8D4C103
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1123016:CL52 RS02505
gene id: 1123016:CL52_RS02505
uniprot id: A0A8D3XZ35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1123016:CL52 RS05965
gene id: 1123016:CL52_RS05965
uniprot id: A0A8D3Y0H1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1123016:CL52 RS02005
gene id: 1123016:CL52_RS02005
uniprot id: A0A8D4C143
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS01670
gene id: 1123016:CL52_RS01670
uniprot id: A0A8D4C179
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1123016:CL52 RS13520
gene id: 1123016:CL52_RS13520
uniprot id: A0A8D3Y2B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1123016:CL52 RS03265
gene id: 1123016:CL52_RS03265
uniprot id: A0A8D3XYK2
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS12060
gene id: 1123016:CL52_RS12060
uniprot id: A0A8D3Y1T2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS02095
gene id: 1123016:CL52_RS02095
uniprot id: A0A8D3XYE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1123016:CL52 RS04615
gene id: 1123016:CL52_RS04615
uniprot id: A0A8D3XZQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1123016:CL52 RS18970
gene id: 1123016:CL52_RS18970
uniprot id: A0A8D3Y4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1123016:CL52 RS10090
gene id: 1123016:CL52_RS10090
uniprot id: A0A8D3Y1B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1123016:CL52 RS13600
gene id: 1123016:CL52_RS13600
uniprot id: A0A8D3Y2C8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1123016:CL52 RS04330
gene id: 1123016:CL52_RS04330
uniprot id: A0A8D3XZ14
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1123016:CL52 RS05510
gene id: 1123016:CL52_RS05510
uniprot id: A0A8D4C678
names: Similarity
names: Subunit
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.
messages: Monomer.

1123016:CL52 RS04515
gene id: 1123016:CL52_RS04515
uniprot id: A0A8D4C1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1123016:CL52 RS02275
gene id: 1123016:CL52_RS02275
uniprot id: A0A8D3XYB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1123016:CL52 RS04430
gene id: 1123016:CL52_RS04430
uniprot id: A0A8D3XYY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1123016:CL52 RS04760
gene id: 1123016:CL52_RS04760
uniprot id: A0A8D4C5K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS12785
gene id: 1123016:CL52_RS12785
uniprot id: A0A8D4C709
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1123016:CL52 RS07195
gene id: 1123016:CL52_RS07195
uniprot id: A0A8D3Y0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1123016:CL52 RS01000
gene id: 1123016:CL52_RS01000
uniprot id: A0A8D4C0Y1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1123016:CL52 RS18640
gene id: 1123016:CL52_RS18640
uniprot id: A0A8D4C850
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS11445
gene id: 1123016:CL52_RS11445
uniprot id: A0A8D4C303
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS13510
gene id: 1123016:CL52_RS13510
uniprot id: A0A8D3Y2J4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1123016:CL52 RS01820
gene id: 1123016:CL52_RS01820
uniprot id: A0A8D3XY62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1123016:CL52 RS18760
gene id: 1123016:CL52_RS18760
uniprot id: A0A8D4C8J7
names: Similarity
messages: Belongs to the YggT family.

1123016:CL52 RS01545
gene id: 1123016:CL52_RS01545
uniprot id: A0A8D3XYE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1123016:CL52 RS20165
gene id: 1123016:CL52_RS20165
uniprot id: A0A8D3Y4Z9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS10470
gene id: 1123016:CL52_RS10470
uniprot id: A0A8D4C350
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS15420
gene id: 1123016:CL52_RS15420
uniprot id: A0A8D4C7I5
names: Similarity
messages: Belongs to the peptidase C56 family.

1123016:CL52 RS06850
gene id: 1123016:CL52_RS06850
uniprot id: A0A8D3Y043
names: Similarity
messages: Belongs to the MlaA family.

1123016:CL52 RS01375
gene id: 1123016:CL52_RS01375
uniprot id: A0A8D4C4X2
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS11555
gene id: 1123016:CL52_RS11555
uniprot id: A0A8D3Y1M2
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS03910
gene id: 1123016:CL52_RS03910
uniprot id: A0A8D3XZA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1123016:CL52 RS07500
gene id: 1123016:CL52_RS07500
uniprot id: A0A8D4C294
names: Subcellular Location Annotation
messages: Cell inner membrane

1123016:CL52 RS12880
gene id: 1123016:CL52_RS12880
uniprot id: A0A8D3Y2Q1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS18725
gene id: 1123016:CL52_RS18725
uniprot id: A0A8D4C4N3
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17330
gene id: 1123016:CL52_RS17330
uniprot id: A0A8D3Y3P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1123016:CL52 RS08840
gene id: 1123016:CL52_RS08840
uniprot id: A0A8D4C6B3
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS11035
gene id: 1123016:CL52_RS11035
uniprot id: A0A8D4C6Q2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1123016:CL52 RS10320
gene id: 1123016:CL52_RS10320
uniprot id: A0A8D3Y1A7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1123016:CL52 RS12585
gene id: 1123016:CL52_RS12585
uniprot id: A0A8D3Y207
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1123016:CL52 RS05585
gene id: 1123016:CL52_RS05585
uniprot id: A0A8D4C679
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

1123016:CL52 RS12750
gene id: 1123016:CL52_RS12750
uniprot id: A0A8D4C7H0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS07045
gene id: 1123016:CL52_RS07045
uniprot id: A0A8D3Y0J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1123016:CL52 RS02140
gene id: 1123016:CL52_RS02140
uniprot id: A0A8D4C026
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS12920
gene id: 1123016:CL52_RS12920
uniprot id: A0A8D4C3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1123016:CL52 RS06500
gene id: 1123016:CL52_RS06500
uniprot id: A0A8D3Y0B5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1123016:CL52 RS03815
gene id: 1123016:CL52_RS03815
uniprot id: A0A8D4C5E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS12265
gene id: 1123016:CL52_RS12265
uniprot id: A0A8D4C360
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1123016:CL52 RS15875
gene id: 1123016:CL52_RS15875
uniprot id: A0A8D4C2T2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1123016:CL52 RS16760
gene id: 1123016:CL52_RS16760
uniprot id: A0A8D4C2Z4
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1123016:CL52 RS06920
gene id: 1123016:CL52_RS06920
uniprot id: A0A8D4C6G2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS08880
gene id: 1123016:CL52_RS08880
uniprot id: A0A8D3Y150
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS00675
gene id: 1123016:CL52_RS00675
uniprot id: A0A8D3XY38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS04040
gene id: 1123016:CL52_RS04040
uniprot id: A0A8D4C5F5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1123016:CL52 RS01190
gene id: 1123016:CL52_RS01190
uniprot id: A0A8D3XYU9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1123016:CL52 RS12625
gene id: 1123016:CL52_RS12625
uniprot id: A0A8D4C243
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1123016:CL52 RS14295
gene id: 1123016:CL52_RS14295
uniprot id: A0A8D3Y2T7
names: Similarity
messages: Belongs to the leucine-binding protein family.

1123016:CL52 RS11890
gene id: 1123016:CL52_RS11890
uniprot id: A0A8D3Y261
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1123016:CL52 RS04020
gene id: 1123016:CL52_RS04020
uniprot id: A0A8D3XZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1123016:CL52 RS17015
gene id: 1123016:CL52_RS17015
uniprot id: A0A8D3Y3S9
names: Similarity
messages: Belongs to the IMPACT family.

1123016:CL52 RS07705
gene id: 1123016:CL52_RS07705
uniprot id: A0A8D3Y0D0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

1123016:CL52 RS02310
gene id: 1123016:CL52_RS02310
uniprot id: A0A8D4C167
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1123016:CL52 RS03990
gene id: 1123016:CL52_RS03990
uniprot id: A0A8D3XZ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1123016:CL52 RS13550
gene id: 1123016:CL52_RS13550
uniprot id: A0A8D3Y2Y3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1123016:CL52 RS12200
gene id: 1123016:CL52_RS12200
uniprot id: A0A8D3Y2G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1123016:CL52 RS10380
gene id: 1123016:CL52_RS10380
uniprot id: A0A8D3Y1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1123016:CL52 RS06555
gene id: 1123016:CL52_RS06555
uniprot id: A0A8D3XZR1
names: Similarity
messages: Belongs to the peptidase C40 family.

1123016:CL52 RS12710
gene id: 1123016:CL52_RS12710
uniprot id: A0A8D3Y225
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1123016:CL52 RS04140
gene id: 1123016:CL52_RS04140
uniprot id: A0A8D3XZ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1123016:CL52 RS08345
gene id: 1123016:CL52_RS08345
uniprot id: A0A8D4C199
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS10115
gene id: 1123016:CL52_RS10115
uniprot id: A0A8D4C6J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS07320
gene id: 1123016:CL52_RS07320
uniprot id: A0A8D4C2I0
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS13430
gene id: 1123016:CL52_RS13430
uniprot id: A0A8D4C2A8
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

1123016:CL52 RS13625
gene id: 1123016:CL52_RS13625
uniprot id: A0A8D3Y2G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS15945
gene id: 1123016:CL52_RS15945
uniprot id: A0A8D3Y387
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1123016:CL52 RS18015
gene id: 1123016:CL52_RS18015
uniprot id: A0A8D3Y3W7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1123016:CL52 RS02325
gene id: 1123016:CL52_RS02325
uniprot id: A0A8D3XYH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1123016:CL52 RS16510
gene id: 1123016:CL52_RS16510
uniprot id: A0A8D3Y3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

1123016:CL52 RS06770
gene id: 1123016:CL52_RS06770
uniprot id: A0A8D4C6F2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1123016:CL52 RS06630
gene id: 1123016:CL52_RS06630
uniprot id: A0A8D3XZS2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1123016:CL52 RS12270
gene id: 1123016:CL52_RS12270
uniprot id: A0A8D3Y1Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1123016:CL52 RS12120
gene id: 1123016:CL52_RS12120
uniprot id: A0A8D3Y1X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1123016:CL52 RS07350
gene id: 1123016:CL52_RS07350
uniprot id: A0A8D3Y0C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS13265
gene id: 1123016:CL52_RS13265
uniprot id: A0A8D4C290
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS04390
gene id: 1123016:CL52_RS04390
uniprot id: A0A8D3XZ75
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1123016:CL52 RS12695
gene id: 1123016:CL52_RS12695
uniprot id: A0A8D3Y218
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1123016:CL52 RS08030
gene id: 1123016:CL52_RS08030
uniprot id: A0A8D3Y0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS15740
gene id: 1123016:CL52_RS15740
uniprot id: A0A8D3Y3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1123016:CL52 RS03420
gene id: 1123016:CL52_RS03420
uniprot id: A0A8D4C5B5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS12380
gene id: 1123016:CL52_RS12380
uniprot id: A0A8D3Y254
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1123016:CL52 RS07080
gene id: 1123016:CL52_RS07080
uniprot id: A0A8D3Y085
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

1123016:CL52 RS14460
gene id: 1123016:CL52_RS14460
uniprot id: A0A8D3Y2U0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123016:CL52 RS11565
gene id: 1123016:CL52_RS11565
uniprot id: A0A8D4C792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS19450
gene id: 1123016:CL52_RS19450
uniprot id: A0A8D3Y4Q2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1123016:CL52 RS10035
gene id: 1123016:CL52_RS10035
uniprot id: A0A8D4C1M3
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1123016:CL52 RS16770
gene id: 1123016:CL52_RS16770
uniprot id: A0A8D3Y3J4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1123016:CL52 RS00085
gene id: 1123016:CL52_RS00085
uniprot id: A0A8D3XYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS03660
gene id: 1123016:CL52_RS03660
uniprot id: A0A8D4C0B8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1123016:CL52 RS14245
gene id: 1123016:CL52_RS14245
uniprot id: A0A8D3Y372
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1123016:CL52 RS10890
gene id: 1123016:CL52_RS10890
uniprot id: A0A8D3Y1H6
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS19845
gene id: 1123016:CL52_RS19845
uniprot id: A0A8D3Y4V8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS16530
gene id: 1123016:CL52_RS16530
uniprot id: A0A8D3Y3E5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1123016:CL52 RS20770
gene id: 1123016:CL52_RS20770
uniprot id: A0A8D4C7R7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1123016:CL52 RS07250
gene id: 1123016:CL52_RS07250
uniprot id: A0A8D4C121
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS11550
gene id: 1123016:CL52_RS11550
uniprot id: A0A8D3Y217
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1123016:CL52 RS04095
gene id: 1123016:CL52_RS04095
uniprot id: A0A8D3XZ50
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS07245
gene id: 1123016:CL52_RS07245
uniprot id: A0A8D3Y060
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1123016:CL52 RS13385
gene id: 1123016:CL52_RS13385
uniprot id: A0A8D3Y2F1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1123016:CL52 RS05915
gene id: 1123016:CL52_RS05915
uniprot id: A0A8D3XZP1
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1123016:CL52 RS08500
gene id: 1123016:CL52_RS08500
uniprot id: A0A8D4C695
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123016:CL52 RS08920
gene id: 1123016:CL52_RS08920
uniprot id: A0A8D4C1D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1123016:CL52 RS04230
gene id: 1123016:CL52_RS04230
uniprot id: A0A8D3XZW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1123016:CL52 RS13010
gene id: 1123016:CL52_RS13010
uniprot id: A0A8D4C271
names: Similarity
messages: Belongs to the CvfB family.

1123016:CL52 RS15135
gene id: 1123016:CL52_RS15135
uniprot id: A0A8D3Y315
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

1123016:CL52 RS11235
gene id: 1123016:CL52_RS11235
uniprot id: A0A8D3Y2D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS09050
gene id: 1123016:CL52_RS09050
uniprot id: A0A8D3Y0X3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1123016:CL52 RS16705
gene id: 1123016:CL52_RS16705
uniprot id: A0A8D3Y3P1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1123016:CL52 RS14960
gene id: 1123016:CL52_RS14960
uniprot id: A0A8D3Y2V3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1123016:CL52 RS04680
gene id: 1123016:CL52_RS04680
uniprot id: A0A8D3XZL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1123016:CL52 RS14390
gene id: 1123016:CL52_RS14390
uniprot id: A0A8D3Y2N5
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1123016:CL52 RS20175
gene id: 1123016:CL52_RS20175
uniprot id: A0A8D3Y5H4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1123016:CL52 RS06075
gene id: 1123016:CL52_RS06075
uniprot id: A0A8D4C5T8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1123016:CL52 RS10335
gene id: 1123016:CL52_RS10335
uniprot id: A0A8D3Y1M4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS12555
gene id: 1123016:CL52_RS12555
uniprot id: A0A8D3Y204
names: Caution
names: Function
names: Similarity
messages: As this bacterium is not an Enterobacterale, this protein may not have a true dGTPase activity.
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

1123016:CL52 RS01540
gene id: 1123016:CL52_RS01540
uniprot id: A0A8D3XYF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1123016:CL52 RS12240
gene id: 1123016:CL52_RS12240
uniprot id: A0A8D4C3I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1123016:CL52 RS04080
gene id: 1123016:CL52_RS04080
uniprot id: A0A8D3XZU5
names: Similarity
messages: Belongs to the SUI1 family.

1123016:CL52 RS06945
gene id: 1123016:CL52_RS06945
uniprot id: A0A8D4C106
names: Subcellular Location Annotation
messages: Cell inner membrane

1123016:CL52 RS16070
gene id: 1123016:CL52_RS16070
uniprot id: A0A8D3Y438
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1123016:CL52 RS12620
gene id: 1123016:CL52_RS12620
uniprot id: A0A8D3Y208
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1123016:CL52 RS19205
gene id: 1123016:CL52_RS19205
uniprot id: A0A8D3Y4M4
names: Similarity
messages: Belongs to the GSP E family.

1123016:CL52 RS13615
gene id: 1123016:CL52_RS13615
uniprot id: A0A8D3Y2E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1123016:CL52 RS05515
gene id: 1123016:CL52_RS05515
uniprot id: A0A8D3XZL5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1123016:CL52 RS01120
gene id: 1123016:CL52_RS01120
uniprot id: A0A8D4C5F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1123016:CL52 RS17225
gene id: 1123016:CL52_RS17225
uniprot id: A0A8D3Y3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1123016:CL52 RS08550
gene id: 1123016:CL52_RS08550
uniprot id: A0A8D3Y0R7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS10500
gene id: 1123016:CL52_RS10500
uniprot id: A0A8D3Y1C9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1123016:CL52 RS00565
gene id: 1123016:CL52_RS00565
uniprot id: A0A8D4C102
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

1123016:CL52 RS08250
gene id: 1123016:CL52_RS08250
uniprot id: A0A8D3Y0L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1123016:CL52 RS07105
gene id: 1123016:CL52_RS07105
uniprot id: A0A8D3XZY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1123016:CL52 RS14455
gene id: 1123016:CL52_RS14455
uniprot id: A0A8D4C7S0
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1123016:CL52 RS08910
gene id: 1123016:CL52_RS08910
uniprot id: A0A8D4C2U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1123016:CL52 RS05850
gene id: 1123016:CL52_RS05850
uniprot id: A0A8D3XZG6
names: Subcellular Location Annotation
messages: Cytoplasm

1123016:CL52 RS14280
gene id: 1123016:CL52_RS14280
uniprot id: A0A8D3Y3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1123016:CL52 RS00395
gene id: 1123016:CL52_RS00395
uniprot id: A0A8D3XYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS11500
gene id: 1123016:CL52_RS11500
uniprot id: A0A8D3Y1L9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1123016:CL52 RS05425
gene id: 1123016:CL52_RS05425
uniprot id: A0A8D3XZC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS20135
gene id: 1123016:CL52_RS20135
uniprot id: A0A8D3Y4Q5
names: Function
names: Similarity
messages: Belongs to the peptidase S1C family.
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

1123016:CL52 RS05330
gene id: 1123016:CL52_RS05330
uniprot id: A0A8D3XZU1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1123016:CL52 RS17885
gene id: 1123016:CL52_RS17885
uniprot id: A0A8D4C4C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1123016:CL52 RS07345
gene id: 1123016:CL52_RS07345
uniprot id: A0A8D4C282
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1123016:CL52 RS06070
gene id: 1123016:CL52_RS06070
uniprot id: A0A8D4C0V6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1123016:CL52 RS06805
gene id: 1123016:CL52_RS06805
uniprot id: A0A8D3XZV3
names: Similarity
messages: Belongs to the peptidase S41A family.

1123016:CL52 RS07180
gene id: 1123016:CL52_RS07180
uniprot id: A0A8D3XZZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1123016:CL52 RS01640
gene id: 1123016:CL52_RS01640
uniprot id: A0A8D3XZ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS03370
gene id: 1123016:CL52_RS03370
uniprot id: A0A8D3XYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1123016:CL52 RS19850
gene id: 1123016:CL52_RS19850
uniprot id: A0A8D3Y4W3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1123016:CL52 RS08005
gene id: 1123016:CL52_RS08005
uniprot id: A0A8D3Y185
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1123016:CL52 RS17615
gene id: 1123016:CL52_RS17615
uniprot id: A0A8D3Y4M9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS16490
gene id: 1123016:CL52_RS16490
uniprot id: A0A8D3Y3Q5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1123016:CL52 RS11255
gene id: 1123016:CL52_RS11255
uniprot id: A0A8D4C3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1123016:CL52 RS05200
gene id: 1123016:CL52_RS05200
uniprot id: A0A8D3Y063
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1123016:CL52 RS19550
gene id: 1123016:CL52_RS19550
uniprot id: A0A8D3Y4K9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1123016:CL52 RS21210
gene id: 1123016:CL52_RS21210
uniprot id: A0A8D3Y511
names: Similarity
messages: Belongs to the transposase 8 family.

1123016:CL52 RS02490
gene id: 1123016:CL52_RS02490
uniprot id: A0A8D3XYS0
names: Similarity
messages: Belongs to the GppA/Ppx family.

1123016:CL52 RS19585
gene id: 1123016:CL52_RS19585
uniprot id: A0A8D4C4T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1123016:CL52 RS15745
gene id: 1123016:CL52_RS15745
uniprot id: A0A8D3Y3A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1123016:CL52 RS04400
gene id: 1123016:CL52_RS04400
uniprot id: A0A8D4C1V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1123016:CL52 RS13170
gene id: 1123016:CL52_RS13170
uniprot id: A0A8D4C285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1123016:CL52 RS00080
gene id: 1123016:CL52_RS00080
uniprot id: A0A8D3XXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS05080
gene id: 1123016:CL52_RS05080
uniprot id: A0A8D4C0N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

1123016:CL52 RS03625
gene id: 1123016:CL52_RS03625
uniprot id: A0A8D3XYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS14935
gene id: 1123016:CL52_RS14935
uniprot id: A0A8D3Y3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS16090
gene id: 1123016:CL52_RS16090
uniprot id: A0A8D4C4E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1123016:CL52 RS10960
gene id: 1123016:CL52_RS10960
uniprot id: A0A8D3Y1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS06030
gene id: 1123016:CL52_RS06030
uniprot id: A0A8D3Y062
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS17905
gene id: 1123016:CL52_RS17905
uniprot id: A0A8D3Y474
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1123016:CL52 RS19180
gene id: 1123016:CL52_RS19180
uniprot id: A0A8D4C887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm

1123016:CL52 RS10460
gene id: 1123016:CL52_RS10460
uniprot id: A0A8D3Y1F2
names: Similarity
messages: Belongs to the MlaA family.

1123016:CL52 RS00895
gene id: 1123016:CL52_RS00895
uniprot id: A0A8D3XXY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS18670
gene id: 1123016:CL52_RS18670
uniprot id: A0A8D3Y4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1123016:CL52 RS08460
gene id: 1123016:CL52_RS08460
uniprot id: A0A8D3Y0K0
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1123016:CL52 RS20245
gene id: 1123016:CL52_RS20245
uniprot id: A0A8D3Y515
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1123016:CL52 RS11640
gene id: 1123016:CL52_RS11640
uniprot id: A0A8D3Y1N3
names: Similarity
messages: Belongs to the GSP E family.

1123016:CL52 RS01465
gene id: 1123016:CL52_RS01465
uniprot id: A0A8D3XYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1123016:CL52 RS11960
gene id: 1123016:CL52_RS11960
uniprot id: A0A8D3Y2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1123016:CL52 RS01380
gene id: 1123016:CL52_RS01380
uniprot id: A0A8D3XXX1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1123016:CL52 RS01935
gene id: 1123016:CL52_RS01935
uniprot id: A0A8D3XYK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1123016:CL52 RS08805
gene id: 1123016:CL52_RS08805
uniprot id: A0A8D3Y0U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1123016:CL52 RS04270
gene id: 1123016:CL52_RS04270
uniprot id: A0A8D3XYX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1123016:CL52 RS02320
gene id: 1123016:CL52_RS02320
uniprot id: A0A8D3XYQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS17685
gene id: 1123016:CL52_RS17685
uniprot id: A0A8D3Y3T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1123016:CL52 RS04360
gene id: 1123016:CL52_RS04360
uniprot id: A0A8D3XZH4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS17075
gene id: 1123016:CL52_RS17075
uniprot id: A0A8D3Y3N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS05355
gene id: 1123016:CL52_RS05355
uniprot id: A0A8D3XZU1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1123016:CL52 RS16650
gene id: 1123016:CL52_RS16650
uniprot id: A0A8D3Y3F4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS17710
gene id: 1123016:CL52_RS17710
uniprot id: A0A8D4C4U2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1123016:CL52 RS06465
gene id: 1123016:CL52_RS06465
uniprot id: A0A8D4C0Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1123016:CL52 RS00170
gene id: 1123016:CL52_RS00170
uniprot id: A0A8D3XXF8
names: Similarity
messages: Belongs to the peptidase S11 family.

1123016:CL52 RS13015
gene id: 1123016:CL52_RS13015
uniprot id: A0A8D4C727
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1123016:CL52 RS08125
gene id: 1123016:CL52_RS08125
uniprot id: A0A8D4C673
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1123016:CL52 RS03795
gene id: 1123016:CL52_RS03795
uniprot id: A0A8D3XZ19
names: Similarity
messages: Belongs to the tannase family.

1123016:CL52 RS15350
gene id: 1123016:CL52_RS15350
uniprot id: A0A8D3Y313
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1123016:CL52 RS05945
gene id: 1123016:CL52_RS05945
uniprot id: A0A8D3Y026
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1123016:CL52 RS19010
gene id: 1123016:CL52_RS19010
uniprot id: A0A8D4C3F9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS07710
gene id: 1123016:CL52_RS07710
uniprot id: A0A8D4C152
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1123016:CL52 RS06560
gene id: 1123016:CL52_RS06560
uniprot id: A0A8D4C224
names: Similarity
messages: Belongs to the peptidase C40 family.

1123016:CL52 RS18305
gene id: 1123016:CL52_RS18305
uniprot id: A0A8D3Y460
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS05410
gene id: 1123016:CL52_RS05410
uniprot id: A0A8D3XZV1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1123016:CL52 RS20255
gene id: 1123016:CL52_RS20255
uniprot id: A0A8D3Y4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1123016:CL52 RS01105
gene id: 1123016:CL52_RS01105
uniprot id: A0A8D3XYK9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1123016:CL52 RS12760
gene id: 1123016:CL52_RS12760
uniprot id: A0A8D3Y2A5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS07745
gene id: 1123016:CL52_RS07745
uniprot id: A0A8D3Y068
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1123016:CL52 RS07885
gene id: 1123016:CL52_RS07885
uniprot id: A0A8D4C165
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS06730
gene id: 1123016:CL52_RS06730
uniprot id: A0A8D3XZT7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1123016:CL52 RS05625
gene id: 1123016:CL52_RS05625
uniprot id: A0A8D3XZD5
names: Similarity
messages: Belongs to the VgrG protein family.

1123016:CL52 RS00510
gene id: 1123016:CL52_RS00510
uniprot id: A0A8D3XXK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS15975
gene id: 1123016:CL52_RS15975
uniprot id: A0A8D3Y3Y4
names: Similarity
messages: Belongs to the UPF0307 family.

1123016:CL52 RS01215
gene id: 1123016:CL52_RS01215
uniprot id: A0A8D3XXV5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1123016:CL52 RS06060
gene id: 1123016:CL52_RS06060
uniprot id: A0A8D4C269
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1123016:CL52 RS13470
gene id: 1123016:CL52_RS13470
uniprot id: A0A8D3Y2G5
names: Similarity
messages: Belongs to the SCO1/2 family.

1123016:CL52 RS08245
gene id: 1123016:CL52_RS08245
uniprot id: A0A8D4C6Q0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1123016:CL52 RS11780
gene id: 1123016:CL52_RS11780
uniprot id: A0A8D3Y2B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1123016:CL52 RS19120
gene id: 1123016:CL52_RS19120
uniprot id: A0A8D3Y4I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1123016:CL52 RS14915
gene id: 1123016:CL52_RS14915
uniprot id: A0A8D3Y3F7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS18595
gene id: 1123016:CL52_RS18595
uniprot id: A0A8D3Y4F6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1123016:CL52 RS11290
gene id: 1123016:CL52_RS11290
uniprot id: A0A8D3Y249
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS01435
gene id: 1123016:CL52_RS01435
uniprot id: A0A8D4C156
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1123016:CL52 RS04685
gene id: 1123016:CL52_RS04685
uniprot id: A0A8D3XZA4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS18080
gene id: 1123016:CL52_RS18080
uniprot id: A0A8D3Y488
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1123016:CL52 RS06970
gene id: 1123016:CL52_RS06970
uniprot id: A0A8D3Y0H5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1123016:CL52 RS18815
gene id: 1123016:CL52_RS18815
uniprot id: A0A8D3Y4H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1123016:CL52 RS01165
gene id: 1123016:CL52_RS01165
uniprot id: A0A8D3XYB0
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1123016:CL52 RS04150
gene id: 1123016:CL52_RS04150
uniprot id: A0A8D3XYX8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS10790
gene id: 1123016:CL52_RS10790
uniprot id: A0A8D3Y1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS18540
gene id: 1123016:CL52_RS18540
uniprot id: A0A8D3Y490
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS15250
gene id: 1123016:CL52_RS15250
uniprot id: A0A8D3Y364
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1123016:CL52 RS06100
gene id: 1123016:CL52_RS06100
uniprot id: A0A8D3XZU8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1123016:CL52 RS15035
gene id: 1123016:CL52_RS15035
uniprot id: A0A8D3Y2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1123016:CL52 RS09485
gene id: 1123016:CL52_RS09485
uniprot id: A0A8D3Y111
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1123016:CL52 RS01730
gene id: 1123016:CL52_RS01730
uniprot id: A0A8D3XZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS10095
gene id: 1123016:CL52_RS10095
uniprot id: A0A8D3Y1B6
names: Subcellular Location Annotation
messages: Cytoplasm

1123016:CL52 RS00135
gene id: 1123016:CL52_RS00135
uniprot id: A0A8D3XXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1123016:CL52 RS14255
gene id: 1123016:CL52_RS14255
uniprot id: A0A8D3Y2Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1123016:CL52 RS03170
gene id: 1123016:CL52_RS03170
uniprot id: A0A8D3XYL1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1123016:CL52 RS07210
gene id: 1123016:CL52_RS07210
uniprot id: A0A8D3Y0I9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1123016:CL52 RS12195
gene id: 1123016:CL52_RS12195
uniprot id: A0A8D3Y1Y6
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1123016:CL52 RS17285
gene id: 1123016:CL52_RS17285
uniprot id: A0A8D3Y3N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1123016:CL52 RS11460
gene id: 1123016:CL52_RS11460
uniprot id: A0A8D3Y1Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1123016:CL52 RS17535
gene id: 1123016:CL52_RS17535
uniprot id: A0A8D3Y4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS16495
gene id: 1123016:CL52_RS16495
uniprot id: A0A8D3Y3D4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

1123016:CL52 RS11470
gene id: 1123016:CL52_RS11470
uniprot id: A0A8D3Y1K9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS16075
gene id: 1123016:CL52_RS16075
uniprot id: A0A8D4C831
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1123016:CL52 RS06125
gene id: 1123016:CL52_RS06125
uniprot id: A0A8D3Y0J3
names: Similarity
messages: Belongs to the RecJ family.

1123016:CL52 RS04440
gene id: 1123016:CL52_RS04440
uniprot id: A0A8D3XZD7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1123016:CL52 RS17865
gene id: 1123016:CL52_RS17865
uniprot id: A0A8D3Y3U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1123016:CL52 RS17265
gene id: 1123016:CL52_RS17265
uniprot id: A0A8D4C8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1123016:CL52 RS19640
gene id: 1123016:CL52_RS19640
uniprot id: A0A8D4C588
names: Similarity
messages: Belongs to the VgrG protein family.

1123016:CL52 RS17250
gene id: 1123016:CL52_RS17250
uniprot id: A0A8D3Y3Z8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1123016:CL52 RS04380
gene id: 1123016:CL52_RS04380
uniprot id: A0A8D3XZX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1123016:CL52 RS14575
gene id: 1123016:CL52_RS14575
uniprot id: A0A8D3Y2R5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1123016:CL52 RS01145
gene id: 1123016:CL52_RS01145
uniprot id: A0A8D4BZV9
names: Similarity
messages: Belongs to the peptidase S41A family.

1123016:CL52 RS08505
gene id: 1123016:CL52_RS08505
uniprot id: A0A8D3Y0K1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS06575
gene id: 1123016:CL52_RS06575
uniprot id: A0A8D3Y003
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1123016:CL52 RS03300
gene id: 1123016:CL52_RS03300
uniprot id: A0A8D3XZJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS14305
gene id: 1123016:CL52_RS14305
uniprot id: A0A8D3Y2M1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS07835
gene id: 1123016:CL52_RS07835
uniprot id: A0A8D3Y0V8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1123016:CL52 RS15765
gene id: 1123016:CL52_RS15765
uniprot id: A0A8D3Y3Y9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1123016:CL52 RS03450
gene id: 1123016:CL52_RS03450
uniprot id: A0A8D3XZC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1123016:CL52 RS13925
gene id: 1123016:CL52_RS13925
uniprot id: A0A8D3Y2H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS12610
gene id: 1123016:CL52_RS12610
uniprot id: A0A8D3Y284
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1123016:CL52 RS13570
gene id: 1123016:CL52_RS13570
uniprot id: A0A8D3Y2C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1123016:CL52 RS17430
gene id: 1123016:CL52_RS17430
uniprot id: A0A8D4C4S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1123016:CL52 RS18160
gene id: 1123016:CL52_RS18160
uniprot id: A0A8D4C4X9
names: Similarity
messages: Belongs to the NodU/CmcH family.

1123016:CL52 RS15730
gene id: 1123016:CL52_RS15730
uniprot id: A0A8D4C3W5
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1123016:CL52 RS19985
gene id: 1123016:CL52_RS19985
uniprot id: A0A8D4C4W8
names: Function
names: Similarity
messages: Belongs to the MdcG family.
messages: Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].

1123016:CL52 RS08410
gene id: 1123016:CL52_RS08410
uniprot id: A0A8D4C2R1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS06485
gene id: 1123016:CL52_RS06485
uniprot id: A0A8D3Y032
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS18085
gene id: 1123016:CL52_RS18085
uniprot id: A0A8D4C4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1123016:CL52 RS03105
gene id: 1123016:CL52_RS03105
uniprot id: A0A8D4C593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS05040
gene id: 1123016:CL52_RS05040
uniprot id: A0A8D3XZT9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1123016:CL52 RS09560
gene id: 1123016:CL52_RS09560
uniprot id: A0A8D4C2N8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1123016:CL52 RS00250
gene id: 1123016:CL52_RS00250
uniprot id: A0A8D3XXP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1123016:CL52 RS11300
gene id: 1123016:CL52_RS11300
uniprot id: A0A8D3Y1Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS18920
gene id: 1123016:CL52_RS18920
uniprot id: A0A8D3Y4L1
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1123016:CL52 RS12615
gene id: 1123016:CL52_RS12615
uniprot id: A0A8D4C3L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1123016:CL52 RS18275
gene id: 1123016:CL52_RS18275
uniprot id: A0A8D3Y4T1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1123016:CL52 RS01515
gene id: 1123016:CL52_RS01515
uniprot id: A0A8D3XXZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1123016:CL52 RS08530
gene id: 1123016:CL52_RS08530
uniprot id: A0A8D3Y122
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1123016:CL52 RS12950
gene id: 1123016:CL52_RS12950
uniprot id: A0A8D3Y293
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS01330
gene id: 1123016:CL52_RS01330
uniprot id: A0A8D3XYP0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123016:CL52 RS13640
gene id: 1123016:CL52_RS13640
uniprot id: A0A8D3Y2R9
names: Similarity
messages: Belongs to the SlyX family.

1123016:CL52 RS12815
gene id: 1123016:CL52_RS12815
uniprot id: A0A8D3Y2I4
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS08115
gene id: 1123016:CL52_RS08115
uniprot id: A0A8D3Y0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1123016:CL52 RS10675
gene id: 1123016:CL52_RS10675
uniprot id: A0A8D3Y255
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1123016:CL52 RS00155
gene id: 1123016:CL52_RS00155
uniprot id: A0A8D3XXE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1123016:CL52 RS03400
gene id: 1123016:CL52_RS03400
uniprot id: A0A8D3XYW8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1123016:CL52 RS05350
gene id: 1123016:CL52_RS05350
uniprot id: A0A8D3Y080
names: Similarity
messages: Belongs to the GST superfamily.

1123016:CL52 RS03405
gene id: 1123016:CL52_RS03405
uniprot id: A0A8D4C1L2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1123016:CL52 RS04045
gene id: 1123016:CL52_RS04045
uniprot id: A0A8D3XYU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1123016:CL52 RS14765
gene id: 1123016:CL52_RS14765
uniprot id: A0A8D3Y3E0
names: Similarity
messages: Belongs to the AAA ATPase family.

1123016:CL52 RS14330
gene id: 1123016:CL52_RS14330
uniprot id: A0A8D3Y2R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1123016:CL52 RS00015
gene id: 1123016:CL52_RS00015
uniprot id: A0A8D4C577
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1123016:CL52 RS16780
gene id: 1123016:CL52_RS16780
uniprot id: A0A8D3Y3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS12775
gene id: 1123016:CL52_RS12775
uniprot id: A0A8D4C256
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1123016:CL52 RS12945
gene id: 1123016:CL52_RS12945
uniprot id: A0A8D4C3A8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1123016:CL52 RS04860
gene id: 1123016:CL52_RS04860
uniprot id: A0A8D3XZN6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS01795
gene id: 1123016:CL52_RS01795
uniprot id: A0A8D3XYA1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1123016:CL52 RS00370
gene id: 1123016:CL52_RS00370
uniprot id: A0A8D3XY08
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1123016:CL52 RS09010
gene id: 1123016:CL52_RS09010
uniprot id: A0A8D4C2K1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

1123016:CL52 RS07945
gene id: 1123016:CL52_RS07945
uniprot id: A0A8D3Y0J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS09365
gene id: 1123016:CL52_RS09365
uniprot id: A0A8D3Y115
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1123016:CL52 RS09280
gene id: 1123016:CL52_RS09280
uniprot id: A0A8D3Y106
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1123016:CL52 RS00005
gene id: 1123016:CL52_RS00005
uniprot id: A0A8D3XX96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1123016:CL52 RS07930
gene id: 1123016:CL52_RS07930
uniprot id: A0A8D3Y177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS07760
gene id: 1123016:CL52_RS07760
uniprot id: A0A8D3Y0U7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1123016:CL52 RS18515
gene id: 1123016:CL52_RS18515
uniprot id: A0A8D3Y4D3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1123016:CL52 RS07955
gene id: 1123016:CL52_RS07955
uniprot id: A0A8D3Y0F7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS08420
gene id: 1123016:CL52_RS08420
uniprot id: A0A8D4C1A3
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1123016:CL52 RS21670
gene id: 1123016:CL52_RS21670
uniprot id: A0A8D3Y2I0
names: Subcellular Location Annotation
messages: Cytoplasm

1123016:CL52 RS13335
gene id: 1123016:CL52_RS13335
uniprot id: A0A8D3Y2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1123016:CL52 RS15670
gene id: 1123016:CL52_RS15670
uniprot id: A0A8D3Y398
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1123016:CL52 RS15105
gene id: 1123016:CL52_RS15105
uniprot id: A0A8D4C455
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123016:CL52 RS09835
gene id: 1123016:CL52_RS09835
uniprot id: A0A8D3Y1W3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-66 and Arg-69) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1123016:CL52 RS09115
gene id: 1123016:CL52_RS09115
uniprot id: A0A8D3Y1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS02710
gene id: 1123016:CL52_RS02710
uniprot id: A0A8D3XZ51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1123016:CL52 RS00385
gene id: 1123016:CL52_RS00385
uniprot id: A0A8D3XYE0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS06455
gene id: 1123016:CL52_RS06455
uniprot id: A0A8D4C2A7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

1123016:CL52 RS19590
gene id: 1123016:CL52_RS19590
uniprot id: A0A8D3Y4Q3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS07845
gene id: 1123016:CL52_RS07845
uniprot id: A0A8D3Y0S3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1123016:CL52 RS19580
gene id: 1123016:CL52_RS19580
uniprot id: A0A8D3Y4J3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1123016:CL52 RS15320
gene id: 1123016:CL52_RS15320
uniprot id: A0A8D3Y348
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1123016:CL52 RS03110
gene id: 1123016:CL52_RS03110
uniprot id: A0A8D3XYI5
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1123016:CL52 RS07765
gene id: 1123016:CL52_RS07765
uniprot id: A0A8D3Y0E5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1123016:CL52 RS04530
gene id: 1123016:CL52_RS04530
uniprot id: A0A8D3XZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1123016:CL52 RS17670
gene id: 1123016:CL52_RS17670
uniprot id: A0A8D3Y4K0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
messages: Homotetramer; dimer of dimers.

1123016:CL52 RS17385
gene id: 1123016:CL52_RS17385
uniprot id: A0A8D3Y3X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1123016:CL52 RS15845
gene id: 1123016:CL52_RS15845
uniprot id: A0A8D3Y405
names: Caution
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1123016:CL52 RS17805
gene id: 1123016:CL52_RS17805
uniprot id: A0A8D3Y3W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS19065
gene id: 1123016:CL52_RS19065
uniprot id: A0A8D3Y5N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS05535
gene id: 1123016:CL52_RS05535
uniprot id: A0A8D4C0R2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS18790
gene id: 1123016:CL52_RS18790
uniprot id: A0A8D4C862
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1123016:CL52 RS03395
gene id: 1123016:CL52_RS03395
uniprot id: A0A8D3XYR9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1123016:CL52 RS20230
gene id: 1123016:CL52_RS20230
uniprot id: A0A8D4C4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1123016:CL52 RS17365
gene id: 1123016:CL52_RS17365
uniprot id: A0A8D4C340
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1123016:CL52 RS05045
gene id: 1123016:CL52_RS05045
uniprot id: A0A8D3XZ79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1123016:CL52 RS11440
gene id: 1123016:CL52_RS11440
uniprot id: A0A8D3Y1L4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS13765
gene id: 1123016:CL52_RS13765
uniprot id: A0A8D3Y2F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS05970
gene id: 1123016:CL52_RS05970
uniprot id: A0A8D4C6A3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS12850
gene id: 1123016:CL52_RS12850
uniprot id: A0A8D3Y242
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1123016:CL52 RS11910
gene id: 1123016:CL52_RS11910
uniprot id: A0A8D4C7B8
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1123016:CL52 RS02845
gene id: 1123016:CL52_RS02845
uniprot id: A0A8D3XYV4
names: Similarity
messages: Belongs to the TrpC family.

1123016:CL52 RS17910
gene id: 1123016:CL52_RS17910
uniprot id: A0A8D3Y3W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1123016:CL52 RS02145
gene id: 1123016:CL52_RS02145
uniprot id: A0A8D4C536
names: Similarity
messages: Belongs to the UPF0758 family.

1123016:CL52 RS09505
gene id: 1123016:CL52_RS09505
uniprot id: A0A8D3Y1C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1123016:CL52 RS10050
gene id: 1123016:CL52_RS10050
uniprot id: A0A8D4C2R8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1123016:CL52 RS14150
gene id: 1123016:CL52_RS14150
uniprot id: A0A8D4C798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS19530
gene id: 1123016:CL52_RS19530
uniprot id: A0A8D3Y4S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS18415
gene id: 1123016:CL52_RS18415
uniprot id: A0A8D3Y450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1123016:CL52 RS01595
gene id: 1123016:CL52_RS01595
uniprot id: A0A8D4BZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1123016:CL52 RS03290
gene id: 1123016:CL52_RS03290
uniprot id: A0A8D3XZB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1123016:CL52 RS18990
gene id: 1123016:CL52_RS18990
uniprot id: A0A8D3Y4E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1123016:CL52 RS19755
gene id: 1123016:CL52_RS19755
uniprot id: A0A8D3Y4U8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1123016:CL52 RS02405
gene id: 1123016:CL52_RS02405
uniprot id: A0A8D4C171
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1123016:CL52 RS08470
gene id: 1123016:CL52_RS08470
uniprot id: A0A8D4C6R4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1123016:CL52 RS08040
gene id: 1123016:CL52_RS08040
uniprot id: A0A8D4C667
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

1123016:CL52 RS02530
gene id: 1123016:CL52_RS02530
uniprot id: A0A8D3XYL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1123016:CL52 RS13845
gene id: 1123016:CL52_RS13845
uniprot id: A0A8D4C778
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS02085
gene id: 1123016:CL52_RS02085
uniprot id: A0A8D3XYM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1123016:CL52 RS12720
gene id: 1123016:CL52_RS12720
uniprot id: A0A8D3Y264
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1123016:CL52 RS01785
gene id: 1123016:CL52_RS01785
uniprot id: A0A8D3XYI9
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS12565
gene id: 1123016:CL52_RS12565
uniprot id: A0A8D3Y241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1123016:CL52 RS11700
gene id: 1123016:CL52_RS11700
uniprot id: A0A8D3Y2A2
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS06900
gene id: 1123016:CL52_RS06900
uniprot id: A0A8D3Y038
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1123016:CL52 RS11205
gene id: 1123016:CL52_RS11205
uniprot id: A0A8D4C2Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS09430
gene id: 1123016:CL52_RS09430
uniprot id: A0A8D3Y0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1123016:CL52 RS04580
gene id: 1123016:CL52_RS04580
uniprot id: A0A8D4C0J4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1123016:CL52 RS03950
gene id: 1123016:CL52_RS03950
uniprot id: A0A8D4C1R2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1123016:CL52 RS10760
gene id: 1123016:CL52_RS10760
uniprot id: A0A8D3Y1C2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS14190
gene id: 1123016:CL52_RS14190
uniprot id: A0A8D3Y3E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1123016:CL52 RS19175
gene id: 1123016:CL52_RS19175
uniprot id: A0A8D4C3H1
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1123016:CL52 RS15890
gene id: 1123016:CL52_RS15890
uniprot id: A0A8D4C3Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS03925
gene id: 1123016:CL52_RS03925
uniprot id: A0A8D3XYV1
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

1123016:CL52 RS03145
gene id: 1123016:CL52_RS03145
uniprot id: A0A8D3XZI0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS18505
gene id: 1123016:CL52_RS18505
uniprot id: A0A8D3Y4A9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123016:CL52 RS05705
gene id: 1123016:CL52_RS05705
uniprot id: A0A8D4C1W4
names: Function
messages: May be involved in the biogenesis of curli organelles.

1123016:CL52 RS14340
gene id: 1123016:CL52_RS14340
uniprot id: A0A8D3Y2R8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1123016:CL52 RS08165
gene id: 1123016:CL52_RS08165
uniprot id: A0A8D3Y1A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1123016:CL52 RS13445
gene id: 1123016:CL52_RS13445
uniprot id: A0A8D4C3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1123016:CL52 RS11240
gene id: 1123016:CL52_RS11240
uniprot id: A0A8D4C772
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS06825
gene id: 1123016:CL52_RS06825
uniprot id: A0A8D3Y029
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1123016:CL52 RS09745
gene id: 1123016:CL52_RS09745
uniprot id: A0A8D3Y146
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1123016:CL52 RS12010
gene id: 1123016:CL52_RS12010
uniprot id: A0A8D4C204
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1123016:CL52 RS08180
gene id: 1123016:CL52_RS08180
uniprot id: A0A8D3Y0M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1123016:CL52 RS19915
gene id: 1123016:CL52_RS19915
uniprot id: A0A8D3Y4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

1123016:CL52 RS05640
gene id: 1123016:CL52_RS05640
uniprot id: A0A8D3XZY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1123016:CL52 RS19930
gene id: 1123016:CL52_RS19930
uniprot id: A0A8D3Y4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS15330
gene id: 1123016:CL52_RS15330
uniprot id: A0A8D4C474
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1123016:CL52 RS13255
gene id: 1123016:CL52_RS13255
uniprot id: A0A8D4C3R4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS10110
gene id: 1123016:CL52_RS10110
uniprot id: A0A8D4C1N3
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1123016:CL52 RS09465
gene id: 1123016:CL52_RS09465
uniprot id: A0A8D4C1I0
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

1123016:CL52 RS08035
gene id: 1123016:CL52_RS08035
uniprot id: A0A8D4C178
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1123016:CL52 RS00305
gene id: 1123016:CL52_RS00305
uniprot id: A0A8D3XXG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS10975
gene id: 1123016:CL52_RS10975
uniprot id: A0A8D3Y1J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1123016:CL52 RS07335
gene id: 1123016:CL52_RS07335
uniprot id: A0A8D4C620
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1123016:CL52 RS11855
gene id: 1123016:CL52_RS11855
uniprot id: A0A8D3Y1U8
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS15115
gene id: 1123016:CL52_RS15115
uniprot id: A0A8D4C2M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123016:CL52 RS19685
gene id: 1123016:CL52_RS19685
uniprot id: A0A8D3Y4U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the agmatine deiminase family.
messages: Homodimer.
messages: Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.

1123016:CL52 RS03570
gene id: 1123016:CL52_RS03570
uniprot id: A0A8D3XYZ4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1123016:CL52 RS13095
gene id: 1123016:CL52_RS13095
uniprot id: A0A8D4C732
names: Similarity
messages: Belongs to the DEAD box helicase family.

1123016:CL52 RS04435
gene id: 1123016:CL52_RS04435
uniprot id: A0A8D4C1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1123016:CL52 RS15180
gene id: 1123016:CL52_RS15180
uniprot id: A0A8D4C461
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1123016:CL52 RS00530
gene id: 1123016:CL52_RS00530
uniprot id: A0A8D3XXS6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1123016:CL52 RS13860
gene id: 1123016:CL52_RS13860
uniprot id: A0A8D3Y2J9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS15710
gene id: 1123016:CL52_RS15710
uniprot id: A0A8D3Y351
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1123016:CL52 RS10705
gene id: 1123016:CL52_RS10705
uniprot id: A0A8D3Y1B3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1123016:CL52 RS04345
gene id: 1123016:CL52_RS04345
uniprot id: A0A8D3XYX5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1123016:CL52 RS12505
gene id: 1123016:CL52_RS12505
uniprot id: A0A8D3Y2E2
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1123016:CL52 RS05065
gene id: 1123016:CL52_RS05065
uniprot id: A0A8D3XZF8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1123016:CL52 RS14095
gene id: 1123016:CL52_RS14095
uniprot id: A0A8D3Y2N8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS15310
gene id: 1123016:CL52_RS15310
uniprot id: A0A8D3Y3U0
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS17695
gene id: 1123016:CL52_RS17695
uniprot id: A0A8D4C8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1123016:CL52 RS19155
gene id: 1123016:CL52_RS19155
uniprot id: A0A8D3Y4F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

1123016:CL52 RS14225
gene id: 1123016:CL52_RS14225
uniprot id: A0A8D4C7A7
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1123016:CL52 RS06695
gene id: 1123016:CL52_RS06695
uniprot id: A0A8D4C6E9
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1123016:CL52 RS02020
gene id: 1123016:CL52_RS02020
uniprot id: A0A8D3XYD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS10085
gene id: 1123016:CL52_RS10085
uniprot id: A0A8D4C710
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1123016:CL52 RS12525
gene id: 1123016:CL52_RS12525
uniprot id: A0A8D3Y260
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS00010
gene id: 1123016:CL52_RS00010
uniprot id: A0A8D3XYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1123016:CL52 RS17405
gene id: 1123016:CL52_RS17405
uniprot id: A0A8D3Y3Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1123016:CL52 RS02975
gene id: 1123016:CL52_RS02975
uniprot id: A0A8D3XYL4
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS07820
gene id: 1123016:CL52_RS07820
uniprot id: A0A8D3Y081
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1123016:CL52 RS01355
gene id: 1123016:CL52_RS01355
uniprot id: A0A8D3XY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS09710
gene id: 1123016:CL52_RS09710
uniprot id: A0A8D3Y0Z9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1123016:CL52 RS02445
gene id: 1123016:CL52_RS02445
uniprot id: A0A8D3XYE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1123016:CL52 RS04505
gene id: 1123016:CL52_RS04505
uniprot id: A0A8D4C5I6
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1123016:CL52 RS16950
gene id: 1123016:CL52_RS16950
uniprot id: A0A8D3Y3I9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123016:CL52 RS16810
gene id: 1123016:CL52_RS16810
uniprot id: A0A8D4C874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1123016:CL52 RS15860
gene id: 1123016:CL52_RS15860
uniprot id: A0A8D3Y3F8
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

1123016:CL52 RS17340
gene id: 1123016:CL52_RS17340
uniprot id: A0A8D4C8A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1123016:CL52 RS18600
gene id: 1123016:CL52_RS18600
uniprot id: A0A8D3Y446
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1123016:CL52 RS15865
gene id: 1123016:CL52_RS15865
uniprot id: A0A8D4C4C1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1123016:CL52 RS08875
gene id: 1123016:CL52_RS08875
uniprot id: A0A8D3Y0T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

1123016:CL52 RS18945
gene id: 1123016:CL52_RS18945
uniprot id: A0A8D3Y4B8
names: Similarity
messages: Belongs to the peptidase C56 family.

1123016:CL52 RS04620
gene id: 1123016:CL52_RS04620
uniprot id: A0A8D3XZ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1123016:CL52 RS06460
gene id: 1123016:CL52_RS06460
uniprot id: A0A8D3XZW7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1123016:CL52 RS09015
gene id: 1123016:CL52_RS09015
uniprot id: A0A8D3Y0W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS10060
gene id: 1123016:CL52_RS10060
uniprot id: A0A8D3Y1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1123016:CL52 RS09620
gene id: 1123016:CL52_RS09620
uniprot id: A0A8D3Y0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS12595
gene id: 1123016:CL52_RS12595
uniprot id: A0A8D3Y2U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1123016:CL52 RS00810
gene id: 1123016:CL52_RS00810
uniprot id: A0A8D3XXS5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123016:CL52 RS17175
gene id: 1123016:CL52_RS17175
uniprot id: A0A8D3Y3Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS18585
gene id: 1123016:CL52_RS18585
uniprot id: A0A8D3Y4X8
names: PTM
messages: Binds 1 heme group per subunit.

1123016:CL52 RS20055
gene id: 1123016:CL52_RS20055
uniprot id: A0A8D3Y4P5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS12210
gene id: 1123016:CL52_RS12210
uniprot id: A0A8D3Y299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1123016:CL52 RS08155
gene id: 1123016:CL52_RS08155
uniprot id: A0A8D3Y0W7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1123016:CL52 RS18215
gene id: 1123016:CL52_RS18215
uniprot id: A0A8D3Y3Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1123016:CL52 RS11810
gene id: 1123016:CL52_RS11810
uniprot id: A0A8D3Y1X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1123016:CL52 RS15175
gene id: 1123016:CL52_RS15175
uniprot id: A0A8D3Y353
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1123016:CL52 RS00865
gene id: 1123016:CL52_RS00865
uniprot id: A0A8D3XXW5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123016:CL52 RS13770
gene id: 1123016:CL52_RS13770
uniprot id: A0A8D4C3G8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1123016:CL52 RS15910
gene id: 1123016:CL52_RS15910
uniprot id: A0A8D3Y3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1123016:CL52 RS04190
gene id: 1123016:CL52_RS04190
uniprot id: A0A8D4C5G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1123016:CL52 RS00935
gene id: 1123016:CL52_RS00935
uniprot id: A0A8D3XY72
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1123016:CL52 RS05690
gene id: 1123016:CL52_RS05690
uniprot id: A0A8D4C0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

1123016:CL52 RS00830
gene id: 1123016:CL52_RS00830
uniprot id: A0A8D3XXQ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS04340
gene id: 1123016:CL52_RS04340
uniprot id: A0A8D4C5H6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1123016:CL52 RS17815
gene id: 1123016:CL52_RS17815
uniprot id: A0A8D3Y422
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1123016:CL52 RS16485
gene id: 1123016:CL52_RS16485
uniprot id: A0A8D3Y3K0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1123016:CL52 RS19865
gene id: 1123016:CL52_RS19865
uniprot id: A0A8D4C8R9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1123016:CL52 RS01570
gene id: 1123016:CL52_RS01570
uniprot id: A0A8D4C5J2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS10945
gene id: 1123016:CL52_RS10945
uniprot id: A0A8D3Y1E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1123016:CL52 RS17040
gene id: 1123016:CL52_RS17040
uniprot id: A0A8D3Y3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1123016:CL52 RS12295
gene id: 1123016:CL52_RS12295
uniprot id: A0A8D3Y2R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS01185
gene id: 1123016:CL52_RS01185
uniprot id: A0A8D3XXU8
names: Subcellular Location Annotation
messages: Nucleus

1123016:CL52 RS15240
gene id: 1123016:CL52_RS15240
uniprot id: A0A8D4C7X1
names: Similarity
messages: Belongs to the YkuD family.

1123016:CL52 RS05925
gene id: 1123016:CL52_RS05925
uniprot id: A0A8D4C5S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1123016:CL52 RS20300
gene id: 1123016:CL52_RS20300
uniprot id: A0A8D3Y4S5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1123016:CL52 RS16395
gene id: 1123016:CL52_RS16395
uniprot id: A0A8D3Y475
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1123016:CL52 RS00365
gene id: 1123016:CL52_RS00365
uniprot id: A0A8D4C0T9
names: Similarity
messages: Belongs to the SCO1/2 family.

1123016:CL52 RS07960
gene id: 1123016:CL52_RS07960
uniprot id: A0A8D4C170
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1123016:CL52 RS15285
gene id: 1123016:CL52_RS15285
uniprot id: A0A8D3Y336
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1123016:CL52 RS19195
gene id: 1123016:CL52_RS19195
uniprot id: A0A8D3Y4J9
names: Similarity
messages: Belongs to the UPF0111 family.

1123016:CL52 RS17455
gene id: 1123016:CL52_RS17455
uniprot id: A0A8D4C496
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1123016:CL52 RS02215
gene id: 1123016:CL52_RS02215
uniprot id: A0A8D4C030
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS20290
gene id: 1123016:CL52_RS20290
uniprot id: A0A8D4C3Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1123016:CL52 RS03550
gene id: 1123016:CL52_RS03550
uniprot id: A0A8D3XYP6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS08240
gene id: 1123016:CL52_RS08240
uniprot id: A0A8D3Y1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1123016:CL52 RS19470
gene id: 1123016:CL52_RS19470
uniprot id: A0A8D4C8P5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1123016:CL52 RS04970
gene id: 1123016:CL52_RS04970
uniprot id: A0A8D3XZD2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1123016:CL52 RS03340
gene id: 1123016:CL52_RS03340
uniprot id: A0A8D3XYK7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1123016:CL52 RS06700
gene id: 1123016:CL52_RS06700
uniprot id: A0A8D3Y028
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1123016:CL52 RS17475
gene id: 1123016:CL52_RS17475
uniprot id: A0A8D3Y3Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1123016:CL52 RS18700
gene id: 1123016:CL52_RS18700
uniprot id: A0A8D4C521
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1123016:CL52 RS04535
gene id: 1123016:CL52_RS04535
uniprot id: A0A8D3XZP7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1123016:CL52 RS07575
gene id: 1123016:CL52_RS07575
uniprot id: A0A8D4C2A1
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1123016:CL52 RS17790
gene id: 1123016:CL52_RS17790
uniprot id: A0A8D3Y3T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS06150
gene id: 1123016:CL52_RS06150
uniprot id: A0A8D3XZS8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS15300
gene id: 1123016:CL52_RS15300
uniprot id: A0A8D3Y3C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1123016:CL52 RS05725
gene id: 1123016:CL52_RS05725
uniprot id: A0A8D3Y027
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS02755
gene id: 1123016:CL52_RS02755
uniprot id: A0A8D4C573
names: Similarity
messages: Belongs to the UPF0229 family.

1123016:CL52 RS01135
gene id: 1123016:CL52_RS01135
uniprot id: A0A8D4C133
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS03935
gene id: 1123016:CL52_RS03935
uniprot id: A0A8D4C5Y3
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS11505
gene id: 1123016:CL52_RS11505
uniprot id: A0A8D4C1X3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS04445
gene id: 1123016:CL52_RS04445
uniprot id: A0A8D3XZI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1123016:CL52 RS16545
gene id: 1123016:CL52_RS16545
uniprot id: A0A8D3Y3G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

1123016:CL52 RS03260
gene id: 1123016:CL52_RS03260
uniprot id: A0A8D4C5A4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1123016:CL52 RS18695
gene id: 1123016:CL52_RS18695
uniprot id: A0A8D3Y4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1123016:CL52 RS11835
gene id: 1123016:CL52_RS11835
uniprot id: A0A8D4C6V0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1123016:CL52 RS14950
gene id: 1123016:CL52_RS14950
uniprot id: A0A8D3Y323
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1123016:CL52 RS15810
gene id: 1123016:CL52_RS15810
uniprot id: A0A8D4C3X3
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS02735
gene id: 1123016:CL52_RS02735
uniprot id: A0A8D3XYM7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1123016:CL52 RS11760
gene id: 1123016:CL52_RS11760
uniprot id: A0A8D4C6U6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS16715
gene id: 1123016:CL52_RS16715
uniprot id: A0A8D3Y3N3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS17425
gene id: 1123016:CL52_RS17425
uniprot id: A0A8D3Y410
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1123016:CL52 RS16630
gene id: 1123016:CL52_RS16630
uniprot id: A0A8D3Y3N2
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS09245
gene id: 1123016:CL52_RS09245
uniprot id: A0A8D3Y0Y7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1123016:CL52 RS01975
gene id: 1123016:CL52_RS01975
uniprot id: A0A8D3XYC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1123016:CL52 RS01740
gene id: 1123016:CL52_RS01740
uniprot id: A0A8D3XY51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123016:CL52 RS16335
gene id: 1123016:CL52_RS16335
uniprot id: A0A8D3Y3L6
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1123016:CL52 RS16020
gene id: 1123016:CL52_RS16020
uniprot id: A0A8D3Y394
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1123016:CL52 RS06955
gene id: 1123016:CL52_RS06955
uniprot id: A0A8D3XZX1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS17150
gene id: 1123016:CL52_RS17150
uniprot id: A0A8D3Y3P0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1123016:CL52 RS17375
gene id: 1123016:CL52_RS17375
uniprot id: A0A8D3Y3R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1123016:CL52 RS10225
gene id: 1123016:CL52_RS10225
uniprot id: A0A8D4C6J8
names: Similarity
messages: Belongs to the MotB family.

1123016:CL52 RS01565
gene id: 1123016:CL52_RS01565
uniprot id: A0A8D3XZ07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS15935
gene id: 1123016:CL52_RS15935
uniprot id: A0A8D3Y3G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1123016:CL52 RS08720
gene id: 1123016:CL52_RS08720
uniprot id: A0A8D4C6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1123016:CL52 RS16640
gene id: 1123016:CL52_RS16640
uniprot id: A0A8D3Y3M2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1123016:CL52 RS04145
gene id: 1123016:CL52_RS04145
uniprot id: A0A8D3XZK3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1123016:CL52 RS17630
gene id: 1123016:CL52_RS17630
uniprot id: A0A8D3Y428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

1123016:CL52 RS18090
gene id: 1123016:CL52_RS18090
uniprot id: A0A8D3Y3Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS13535
gene id: 1123016:CL52_RS13535
uniprot id: A0A8D3Y2C6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1123016:CL52 RS09150
gene id: 1123016:CL52_RS09150
uniprot id: A0A8D4C6D2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1123016:CL52 RS16050
gene id: 1123016:CL52_RS16050
uniprot id: A0A8D3Y3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS09105
gene id: 1123016:CL52_RS09105
uniprot id: A0A8D3Y178
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1123016:CL52 RS03280
gene id: 1123016:CL52_RS03280
uniprot id: A0A8D3XYZ7
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.

1123016:CL52 RS08855
gene id: 1123016:CL52_RS08855
uniprot id: A0A8D3Y0U5
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1123016:CL52 RS08295
gene id: 1123016:CL52_RS08295
uniprot id: A0A8D3Y114
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS13590
gene id: 1123016:CL52_RS13590
uniprot id: A0A8D3Y2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1123016:CL52 RS20205
gene id: 1123016:CL52_RS20205
uniprot id: A0A8D4C5C6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS15165
gene id: 1123016:CL52_RS15165
uniprot id: A0A8D4C7W6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1123016:CL52 RS05145
gene id: 1123016:CL52_RS05145
uniprot id: A0A8D4C205
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1123016:CL52 RS08940
gene id: 1123016:CL52_RS08940
uniprot id: A0A8D3Y0V3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1123016:CL52 RS02865
gene id: 1123016:CL52_RS02865
uniprot id: A0A8D3XYG6
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS12105
gene id: 1123016:CL52_RS12105
uniprot id: A0A8D4C6W6
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1123016:CL52 RS14285
gene id: 1123016:CL52_RS14285
uniprot id: A0A8D4C7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1123016:CL52 RS01690
gene id: 1123016:CL52_RS01690
uniprot id: A0A8D4C4Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1123016:CL52 RS17390
gene id: 1123016:CL52_RS17390
uniprot id: A0A8D3Y4H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1123016:CL52 RS14875
gene id: 1123016:CL52_RS14875
uniprot id: A0A8D3Y314
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1123016:CL52 RS19840
gene id: 1123016:CL52_RS19840
uniprot id: A0A8D3Y5E0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS13320
gene id: 1123016:CL52_RS13320
uniprot id: A0A8D3Y296
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1123016:CL52 RS15725
gene id: 1123016:CL52_RS15725
uniprot id: A0A8D3Y367
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS12225
gene id: 1123016:CL52_RS12225
uniprot id: A0A8D4C7D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1123016:CL52 RS15510
gene id: 1123016:CL52_RS15510
uniprot id: A0A8D3Y371
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1123016:CL52 RS04495
gene id: 1123016:CL52_RS04495
uniprot id: A0A8D4C0I9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1123016:CL52 RS16585
gene id: 1123016:CL52_RS16585
uniprot id: A0A8D4C859
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1123016:CL52 RS16045
gene id: 1123016:CL52_RS16045
uniprot id: A0A8D3Y3F9
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS12770
gene id: 1123016:CL52_RS12770
uniprot id: A0A8D3Y233
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS02795
gene id: 1123016:CL52_RS02795
uniprot id: A0A8D3XZE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1123016:CL52 RS00580
gene id: 1123016:CL52_RS00580
uniprot id: A0A8D4C4R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS03240
gene id: 1123016:CL52_RS03240
uniprot id: A0A8D4C1J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1123016:CL52 RS19240
gene id: 1123016:CL52_RS19240
uniprot id: A0A8D4C562
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1123016:CL52 RS03915
gene id: 1123016:CL52_RS03915
uniprot id: A0A8D3XZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS15665
gene id: 1123016:CL52_RS15665
uniprot id: A0A8D3Y3T0
names: Similarity
messages: Belongs to the bacterioferritin family.

1123016:CL52 RS15940
gene id: 1123016:CL52_RS15940
uniprot id: A0A8D4C4C6
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1123016:CL52 RS07755
gene id: 1123016:CL52_RS07755
uniprot id: A0A8D3Y0G3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS09545
gene id: 1123016:CL52_RS09545
uniprot id: A0A8D4C1I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1123016:CL52 RS08170
gene id: 1123016:CL52_RS08170
uniprot id: A0A8D4C6P6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

1123016:CL52 RS11635
gene id: 1123016:CL52_RS11635
uniprot id: A0A8D3Y232
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS13340
gene id: 1123016:CL52_RS13340
uniprot id: A0A8D3Y2H4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1123016:CL52 RS04025
gene id: 1123016:CL52_RS04025
uniprot id: A0A8D4C1R7
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1123016:CL52 RS10625
gene id: 1123016:CL52_RS10625
uniprot id: A0A8D3Y1A4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1123016:CL52 RS05140
gene id: 1123016:CL52_RS05140
uniprot id: A0A8D3XZG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1123016:CL52 RS10155
gene id: 1123016:CL52_RS10155
uniprot id: A0A8D3Y149
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS07165
gene id: 1123016:CL52_RS07165
uniprot id: A0A8D3Y053
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1123016:CL52 RS02265
gene id: 1123016:CL52_RS02265
uniprot id: A0A8D3XZ78
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS18005
gene id: 1123016:CL52_RS18005
uniprot id: A0A8D3Y480
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS19950
gene id: 1123016:CL52_RS19950
uniprot id: A0A8D3Y4R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123016:CL52 RS08795
gene id: 1123016:CL52_RS08795
uniprot id: A0A8D3Y1I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1123016:CL52 RS03460
gene id: 1123016:CL52_RS03460
uniprot id: A0A8D3XZL3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1123016:CL52 RS06510
gene id: 1123016:CL52_RS06510
uniprot id: A0A8D3XZT6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1123016:CL52 RS07990
gene id: 1123016:CL52_RS07990
uniprot id: A0A8D3Y0H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1123016:CL52 RS13540
gene id: 1123016:CL52_RS13540
uniprot id: A0A8D4C3F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1123016:CL52 RS04605
gene id: 1123016:CL52_RS04605
uniprot id: A0A8D3XZJ6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1123016:CL52 RS06755
gene id: 1123016:CL52_RS06755
uniprot id: A0A8D3Y0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1123016:CL52 RS12725
gene id: 1123016:CL52_RS12725
uniprot id: A0A8D3Y2N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1123016:CL52 RS09725
gene id: 1123016:CL52_RS09725
uniprot id: A0A8D3Y116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1123016:CL52 RS10660
gene id: 1123016:CL52_RS10660
uniprot id: A0A8D3Y1G3
names: Similarity
messages: Belongs to the BolA/IbaG family.

1123016:CL52 RS07520
gene id: 1123016:CL52_RS07520
uniprot id: A0A8D3Y0N2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS14385
gene id: 1123016:CL52_RS14385
uniprot id: A0A8D4C403
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1123016:CL52 RS19190
gene id: 1123016:CL52_RS19190
uniprot id: A0A8D4C4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1123016:CL52 RS07215
gene id: 1123016:CL52_RS07215
uniprot id: A0A8D3Y036
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1123016:CL52 RS04525
gene id: 1123016:CL52_RS04525
uniprot id: A0A8D3XZJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1123016:CL52 RS18430
gene id: 1123016:CL52_RS18430
uniprot id: A0A8D3Y498
names: Similarity
messages: Belongs to the DEAD box helicase family.

1123016:CL52 RS06620
gene id: 1123016:CL52_RS06620
uniprot id: A0A8D4C0Y7
names: Similarity
messages: Belongs to the UPF0260 family.

1123016:CL52 RS08020
gene id: 1123016:CL52_RS08020
uniprot id: A0A8D3Y0J9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1123016:CL52 RS07635
gene id: 1123016:CL52_RS07635
uniprot id: A0A8D4C146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1123016:CL52 RS05950
gene id: 1123016:CL52_RS05950
uniprot id: A0A8D3XZS9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1123016:CL52 RS15855
gene id: 1123016:CL52_RS15855
uniprot id: A0A8D3Y3C0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1123016:CL52 RS15185
gene id: 1123016:CL52_RS15185
uniprot id: A0A8D3Y2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1123016:CL52 RS12000
gene id: 1123016:CL52_RS12000
uniprot id: A0A8D4C3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS08820
gene id: 1123016:CL52_RS08820
uniprot id: A0A8D3Y0Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1123016:CL52 RS06960
gene id: 1123016:CL52_RS06960
uniprot id: A0A8D4C252
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1123016:CL52 RS04550
gene id: 1123016:CL52_RS04550
uniprot id: A0A8D4C622
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS15075
gene id: 1123016:CL52_RS15075
uniprot id: A0A8D3Y393
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1123016:CL52 RS05525
gene id: 1123016:CL52_RS05525
uniprot id: A0A8D4C230
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123016:CL52 RS02555
gene id: 1123016:CL52_RS02555
uniprot id: A0A8D4C564
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1123016:CL52 RS06835
gene id: 1123016:CL52_RS06835
uniprot id: A0A8D3XZY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1123016:CL52 RS04600
gene id: 1123016:CL52_RS04600
uniprot id: A0A8D3XZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1123016:CL52 RS15690
gene id: 1123016:CL52_RS15690
uniprot id: A0A8D4C804
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1123016:CL52 RS09065
gene id: 1123016:CL52_RS09065
uniprot id: A0A8D3Y0S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Cytoplasm

1123016:CL52 RS02840
gene id: 1123016:CL52_RS02840
uniprot id: A0A8D4C1A9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS06270
gene id: 1123016:CL52_RS06270
uniprot id: A0A8D3Y088
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

1123016:CL52 RS13115
gene id: 1123016:CL52_RS13115
uniprot id: A0A8D3Y2T1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1123016:CL52 RS05020
gene id: 1123016:CL52_RS05020
uniprot id: A0A8D3XZQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1123016:CL52 RS09880
gene id: 1123016:CL52_RS09880
uniprot id: A0A8D4C2Q8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS01235
gene id: 1123016:CL52_RS01235
uniprot id: A0A8D4C0Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1123016:CL52 RS10935
gene id: 1123016:CL52_RS10935
uniprot id: A0A8D3Y1L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS13855
gene id: 1123016:CL52_RS13855
uniprot id: A0A8D4C3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1123016:CL52 RS18755
gene id: 1123016:CL52_RS18755
uniprot id: A0A8D3Y522
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1123016:CL52 RS19185
gene id: 1123016:CL52_RS19185
uniprot id: A0A8D3Y4E9
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1123016:CL52 RS01870
gene id: 1123016:CL52_RS01870
uniprot id: A0A8D3XYB6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123016:CL52 RS05205
gene id: 1123016:CL52_RS05205
uniprot id: A0A8D4C658
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS05405
gene id: 1123016:CL52_RS05405
uniprot id: A0A8D3XZP0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1123016:CL52 RS07905
gene id: 1123016:CL52_RS07905
uniprot id: A0A8D3Y0I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1123016:CL52 RS20280
gene id: 1123016:CL52_RS20280
uniprot id: A0A8D4C5D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1123016:CL52 RS10620
gene id: 1123016:CL52_RS10620
uniprot id: A0A8D4C363
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS07880
gene id: 1123016:CL52_RS07880
uniprot id: A0A8D3Y0E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS08930
gene id: 1123016:CL52_RS08930
uniprot id: A0A8D3Y0P6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123016:CL52 RS06195
gene id: 1123016:CL52_RS06195
uniprot id: A0A8D3XZN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1123016:CL52 RS04030
gene id: 1123016:CL52_RS04030
uniprot id: A0A8D3XYW6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1123016:CL52 RS19375
gene id: 1123016:CL52_RS19375
uniprot id: A0A8D3Y4P2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1123016:CL52 RS19920
gene id: 1123016:CL52_RS19920
uniprot id: A0A8D3Y5E9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1123016:CL52 RS07425
gene id: 1123016:CL52_RS07425
uniprot id: A0A8D3Y0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1123016:CL52 RS03800
gene id: 1123016:CL52_RS03800
uniprot id: A0A8D4C1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1123016:CL52 RS17300
gene id: 1123016:CL52_RS17300
uniprot id: A0A8D3Y3Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1123016:CL52 RS10560
gene id: 1123016:CL52_RS10560
uniprot id: A0A8D4C6M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1123016:CL52 RS01750
gene id: 1123016:CL52_RS01750
uniprot id: A0A8D4C186
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS11385
gene id: 1123016:CL52_RS11385
uniprot id: A0A8D3Y2E6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1123016:CL52 RS08175
gene id: 1123016:CL52_RS08175
uniprot id: A0A8D3Y0L2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1123016:CL52 RS07395
gene id: 1123016:CL52_RS07395
uniprot id: A0A8D4C2I6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1123016:CL52 RS16690
gene id: 1123016:CL52_RS16690
uniprot id: A0A8D4C7S2
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS01410
gene id: 1123016:CL52_RS01410
uniprot id: A0A8D3XXX5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1123016:CL52 RS00690
gene id: 1123016:CL52_RS00690
uniprot id: A0A8D3XYG9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1123016:CL52 RS13575
gene id: 1123016:CL52_RS13575
uniprot id: A0A8D3Y370
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1123016:CL52 RS16015
gene id: 1123016:CL52_RS16015
uniprot id: A0A8D4C4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1123016:CL52 RS15025
gene id: 1123016:CL52_RS15025
uniprot id: A0A8D3Y333
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1123016:CL52 RS13990
gene id: 1123016:CL52_RS13990
uniprot id: A0A8D4C2E5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1123016:CL52 RS12500
gene id: 1123016:CL52_RS12500
uniprot id: A0A8D3Y236
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1123016:CL52 RS15705
gene id: 1123016:CL52_RS15705
uniprot id: A0A8D4C4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1123016:CL52 RS03945
gene id: 1123016:CL52_RS03945
uniprot id: A0A8D3XZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1123016:CL52 RS05800
gene id: 1123016:CL52_RS05800
uniprot id: A0A8D3Y035
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS14730
gene id: 1123016:CL52_RS14730
uniprot id: A0A8D4C514
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS08335
gene id: 1123016:CL52_RS08335
uniprot id: A0A8D4C2Q6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS17130
gene id: 1123016:CL52_RS17130
uniprot id: A0A8D4C4Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1123016:CL52 RS11360
gene id: 1123016:CL52_RS11360
uniprot id: A0A8D3Y1P0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123016:CL52 RS09135
gene id: 1123016:CL52_RS09135
uniprot id: A0A8D4C2W3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1123016:CL52 RS13630
gene id: 1123016:CL52_RS13630
uniprot id: A0A8D3Y2Z5
names: Similarity
messages: Belongs to the Dps family.

1123016:CL52 RS11370
gene id: 1123016:CL52_RS11370
uniprot id: A0A8D3Y1P7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1123016:CL52 RS08600
gene id: 1123016:CL52_RS08600
uniprot id: A0A8D4C2H6
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS13930
gene id: 1123016:CL52_RS13930
uniprot id: A0A8D4C3H9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1123016:CL52 RS07750
gene id: 1123016:CL52_RS07750
uniprot id: A0A8D4C2B1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1123016:CL52 RS02080
gene id: 1123016:CL52_RS02080
uniprot id: A0A8D4C149
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1123016:CL52 RS07940
gene id: 1123016:CL52_RS07940
uniprot id: A0A8D3Y0I6
names: Similarity
messages: Belongs to the SCO1/2 family.

1123016:CL52 RS06780
gene id: 1123016:CL52_RS06780
uniprot id: A0A8D3Y041
names: Subcellular Location Annotation
messages: Membrane

1123016:CL52 RS05300
gene id: 1123016:CL52_RS05300
uniprot id: A0A8D3XZG4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1123016:CL52 RS12185
gene id: 1123016:CL52_RS12185
uniprot id: A0A8D3Y1V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1123016:CL52 RS15495
gene id: 1123016:CL52_RS15495
uniprot id: A0A8D4C7J2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1123016:CL52 RS13215
gene id: 1123016:CL52_RS13215
uniprot id: A0A8D3Y332
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1123016:CL52 RS19730
gene id: 1123016:CL52_RS19730
uniprot id: A0A8D4C8C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).