1122961:PTO RS05065
gene id: 1122961:PTO_RS05065
uniprot id: Q6L0F8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1122961:PTO RS00265
gene id: 1122961:PTO_RS00265
uniprot id: Q6L313
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

1122961:PTO RS04580
gene id: 1122961:PTO_RS04580
uniprot id: Q6L0Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

1122961:PTO RS04760
gene id: 1122961:PTO_RS04760
uniprot id: Q6L0L8
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1122961:PTO RS02275
gene id: 1122961:PTO_RS02275
uniprot id: Q6L1Y7
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1122961:PTO RS04150
gene id: 1122961:PTO_RS04150
uniprot id: Q6L0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1122961:PTO RS07925
gene id: 1122961:PTO_RS07925
uniprot id: Q6KYU4
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1122961:PTO RS02725
gene id: 1122961:PTO_RS02725
uniprot id: Q6L1Q0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1122961:PTO RS00060
gene id: 1122961:PTO_RS00060
uniprot id: Q6L353
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

1122961:PTO RS06025
gene id: 1122961:PTO_RS06025
uniprot id: Q6KZW9
names: Similarity
messages: Belongs to the DtxR/MntR family.

1122961:PTO RS02875
gene id: 1122961:PTO_RS02875
uniprot id: Q6L1M1
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1122961:PTO RS01170
gene id: 1122961:PTO_RS01170
uniprot id: Q6L2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1122961:PTO RS07845
gene id: 1122961:PTO_RS07845
uniprot id: Q6KYW0
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS04450
gene id: 1122961:PTO_RS04450
uniprot id: Q6L0S6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1122961:PTO RS07495
gene id: 1122961:PTO_RS07495
uniprot id: Q6KZ30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

1122961:PTO RS07985
gene id: 1122961:PTO_RS07985
uniprot id: Q6KYT3
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS03450
gene id: 1122961:PTO_RS03450
uniprot id: Q6L1B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1122961:PTO RS03820
gene id: 1122961:PTO_RS03820
uniprot id: Q6L144
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1122961:PTO RS06750
gene id: 1122961:PTO_RS06750
uniprot id: Q6KZH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1122961:PTO RS03045
gene id: 1122961:PTO_RS03045
uniprot id: Q6L1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS02150
gene id: 1122961:PTO_RS02150
uniprot id: Q6L212
names: Similarity
messages: Belongs to the eIF-2-alpha family.

1122961:PTO RS04325
gene id: 1122961:PTO_RS04325
uniprot id: Q6L0V1
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1122961:PTO RS06710
gene id: 1122961:PTO_RS06710
uniprot id: A0A8G2FX35
uniprot id: Q6KZI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03120
gene id: 1122961:PTO_RS03120
uniprot id: A0A8G2L722
uniprot id: Q6L1H6
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS04610
gene id: 1122961:PTO_RS04610
uniprot id: Q6L0P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1122961:PTO RS02895
gene id: 1122961:PTO_RS02895
uniprot id: Q6L1L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1122961:PTO RS03105
gene id: 1122961:PTO_RS03105
uniprot id: Q6L1H9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1122961:PTO RS03475
gene id: 1122961:PTO_RS03475
uniprot id: A0A8G2FVY1
uniprot id: Q6L1B1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1122961:PTO RS07295
gene id: 1122961:PTO_RS07295
uniprot id: Q6KZ70
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

1122961:PTO RS00540
gene id: 1122961:PTO_RS00540
uniprot id: Q6L2W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1122961:PTO RS02610
gene id: 1122961:PTO_RS02610
uniprot id: Q6L1S2
names: Similarity
messages: Belongs to the ZPR1 family.

1122961:PTO RS00450
gene id: 1122961:PTO_RS00450
uniprot id: Q6L2X9
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS00800
gene id: 1122961:PTO_RS00800
uniprot id: Q6L2R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1122961:PTO RS06510
gene id: 1122961:PTO_RS06510
uniprot id: Q6KZM6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1122961:PTO RS06180
gene id: 1122961:PTO_RS06180
uniprot id: Q6KZU0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1122961:PTO RS00875
gene id: 1122961:PTO_RS00875
uniprot id: Q6L2P7
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1122961:PTO RS02585
gene id: 1122961:PTO_RS02585
uniprot id: Q6L1S7
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

1122961:PTO RS02060
gene id: 1122961:PTO_RS02060
uniprot id: Q6L229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1122961:PTO RS02070
gene id: 1122961:PTO_RS02070
uniprot id: A0A8G2FWH5
uniprot id: Q6L227
names: Caution
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03990
gene id: 1122961:PTO_RS03990
uniprot id: Q6L110
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1122961:PTO RS01740
gene id: 1122961:PTO_RS01740
uniprot id: Q6L288
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1122961:PTO RS04575
gene id: 1122961:PTO_RS04575
uniprot id: Q6L0Q1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

1122961:PTO RS06125
gene id: 1122961:PTO_RS06125
uniprot id: Q6KZV1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1122961:PTO RS02040
gene id: 1122961:PTO_RS02040
uniprot id: Q6L233
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

1122961:PTO RS07200
gene id: 1122961:PTO_RS07200
uniprot id: Q6KZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

1122961:PTO RS00070
gene id: 1122961:PTO_RS00070
uniprot id: Q6L351
names: Similarity
messages: Belongs to the peptidase S13 family.

1122961:PTO RS01055
gene id: 1122961:PTO_RS01055
uniprot id: A0A8G2FY83
uniprot id: Q6L2L3
names: Caution
names: Similarity
messages: Belongs to the PDCD5 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02500
gene id: 1122961:PTO_RS02500
uniprot id: Q6L1U4
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS07470
gene id: 1122961:PTO_RS07470
uniprot id: Q6KZ35
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1122961:PTO RS08070
gene id: 1122961:PTO_RS08070
uniprot id: Q6L1P0
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1122961:PTO RS03495
gene id: 1122961:PTO_RS03495
uniprot id: A0A8G2L7L6
uniprot id: Q6L1A7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: With S4 and S12 plays an important role in translational accuracy.

1122961:PTO RS05825
gene id: 1122961:PTO_RS05825
uniprot id: Q6L008
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1122961:PTO RS07030
gene id: 1122961:PTO_RS07030
uniprot id: Q6KZC5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1122961:PTO RS03050
gene id: 1122961:PTO_RS03050
uniprot id: Q6L1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS00735
gene id: 1122961:PTO_RS00735
uniprot id: Q6L2S4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1122961:PTO RS00470
gene id: 1122961:PTO_RS00470
uniprot id: Q6L2X5
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1122961:PTO RS00460
gene id: 1122961:PTO_RS00460
uniprot id: Q6L2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS03515
gene id: 1122961:PTO_RS03515
uniprot id: Q6L1A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

1122961:PTO RS05640
gene id: 1122961:PTO_RS05640
uniprot id: Q6L046
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1122961:PTO RS00550
gene id: 1122961:PTO_RS00550
uniprot id: Q6L2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1122961:PTO RS03470
gene id: 1122961:PTO_RS03470
uniprot id: A0A8G2FVY6
uniprot id: Q6L1B2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS06115
gene id: 1122961:PTO_RS06115
uniprot id: Q6KZV3
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1122961:PTO RS05100
gene id: 1122961:PTO_RS05100
uniprot id: A0A8G2FX82
uniprot id: Q6L0F2
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS07855
gene id: 1122961:PTO_RS07855
uniprot id: Q6KYV8
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS05485
gene id: 1122961:PTO_RS05485
uniprot id: Q6L077
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1122961:PTO RS01135
gene id: 1122961:PTO_RS01135
uniprot id: Q6L2J7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

1122961:PTO RS05645
gene id: 1122961:PTO_RS05645
uniprot id: Q6L045
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS01935
gene id: 1122961:PTO_RS01935
uniprot id: Q6L253
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS02620
gene id: 1122961:PTO_RS02620
uniprot id: Q6L1S0
names: Similarity
messages: Belongs to the isopentenyl phosphate kinase family.

1122961:PTO RS01490
gene id: 1122961:PTO_RS01490
uniprot id: Q6L2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1122961:PTO RS02200
gene id: 1122961:PTO_RS02200
uniprot id: A0A8G2FWD6
uniprot id: Q6L202
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1122961:PTO RS04290
gene id: 1122961:PTO_RS04290
uniprot id: Q6L0V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1122961:PTO RS07880
gene id: 1122961:PTO_RS07880
uniprot id: Q6KYV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1122961:PTO RS03895
gene id: 1122961:PTO_RS03895
uniprot id: Q6L128
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1122961:PTO RS06480
gene id: 1122961:PTO_RS06480
uniprot id: Q6KZN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Membrane

1122961:PTO RS07095
gene id: 1122961:PTO_RS07095
uniprot id: A0A8G2L7D1
uniprot id: Q6KZB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05130
gene id: 1122961:PTO_RS05130
uniprot id: Q6L0E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1122961:PTO RS03155
gene id: 1122961:PTO_RS03155
uniprot id: Q6L1H0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1122961:PTO RS05010
gene id: 1122961:PTO_RS05010
uniprot id: Q6L0G9
names: Similarity
messages: Belongs to the ferrochelatase family.

1122961:PTO RS02935
gene id: 1122961:PTO_RS02935
uniprot id: Q6L1K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).

1122961:PTO RS05320
gene id: 1122961:PTO_RS05320
uniprot id: Q6L0A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

1122961:PTO RS06720
gene id: 1122961:PTO_RS06720
uniprot id: A0A8G2L857
uniprot id: Q6KZI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02075
gene id: 1122961:PTO_RS02075
uniprot id: Q6L226
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1122961:PTO RS07175
gene id: 1122961:PTO_RS07175
uniprot id: Q6KZ96
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1122961:PTO RS00240
gene id: 1122961:PTO_RS00240
uniprot id: Q6L317
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1122961:PTO RS05660
gene id: 1122961:PTO_RS05660
uniprot id: Q6L042
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1122961:PTO RS02395
gene id: 1122961:PTO_RS02395
uniprot id: Q6L1W3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

1122961:PTO RS06660
gene id: 1122961:PTO_RS06660
uniprot id: Q6KZJ7
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

1122961:PTO RS05405
gene id: 1122961:PTO_RS05405
uniprot id: Q6L092
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1122961:PTO RS03225
gene id: 1122961:PTO_RS03225
uniprot id: Q6L1F8
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS01060
gene id: 1122961:PTO_RS01060
uniprot id: A0A8G2FY42
uniprot id: Q6L2L2
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02090
gene id: 1122961:PTO_RS02090
uniprot id: Q6L223
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1122961:PTO RS00945
gene id: 1122961:PTO_RS00945
uniprot id: Q6L2N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1122961:PTO RS07525
gene id: 1122961:PTO_RS07525
uniprot id: A0A8G2FWS7
uniprot id: Q6KZ24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02675
gene id: 1122961:PTO_RS02675
uniprot id: A0A8G2FW74
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00075
gene id: 1122961:PTO_RS00075
uniprot id: Q6L350
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1122961:PTO RS00010
gene id: 1122961:PTO_RS00010
uniprot id: Q6L363
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1122961:PTO RS05460
gene id: 1122961:PTO_RS05460
uniprot id: Q6L082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS04700
gene id: 1122961:PTO_RS04700
uniprot id: Q6L0M8
names: Similarity
messages: Belongs to the citrate synthase family.

1122961:PTO RS03425
gene id: 1122961:PTO_RS03425
uniprot id: A0A8G2L6Y1
uniprot id: Q6L1C0
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02310
gene id: 1122961:PTO_RS02310
uniprot id: A0A8G2FWC2
uniprot id: Q6L1Y0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03875
gene id: 1122961:PTO_RS03875
uniprot id: Q6L132
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1122961:PTO RS02605
gene id: 1122961:PTO_RS02605
uniprot id: Q6L1S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

1122961:PTO RS00775
gene id: 1122961:PTO_RS00775
uniprot id: Q6L2R7
names: Similarity
messages: Belongs to the group II decarboxylase family.

1122961:PTO RS06360
gene id: 1122961:PTO_RS06360
uniprot id: Q6KZQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

1122961:PTO RS05895
gene id: 1122961:PTO_RS05895
uniprot id: Q6KZZ4
names: Similarity
messages: Belongs to the SfsA family.

1122961:PTO RS01830
gene id: 1122961:PTO_RS01830
uniprot id: A0A8G2FWJ7
uniprot id: Q6L270
names: Caution
names: Similarity
messages: Belongs to the UPF0145 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03235
gene id: 1122961:PTO_RS03235
uniprot id: A0A8G2FW11
uniprot id: Q6L1F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03390
gene id: 1122961:PTO_RS03390
uniprot id: Q6L1C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

1122961:PTO RS06045
gene id: 1122961:PTO_RS06045
uniprot id: Q6KZW6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1122961:PTO RS04270
gene id: 1122961:PTO_RS04270
uniprot id: A0A8G2L7G5
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS06665
gene id: 1122961:PTO_RS06665
uniprot id: Q6KZJ6
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1122961:PTO RS01430
gene id: 1122961:PTO_RS01430
uniprot id: Q6L2E5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1122961:PTO RS06435
gene id: 1122961:PTO_RS06435
uniprot id: Q6KZP1
names: Similarity
messages: Belongs to the PGI/PMI family.

1122961:PTO RS06925
gene id: 1122961:PTO_RS06925
uniprot id: Q6KZE5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1122961:PTO RS01555
gene id: 1122961:PTO_RS01555
uniprot id: Q6L2C0
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS05000
gene id: 1122961:PTO_RS05000
uniprot id: Q6L0H1
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS02750
gene id: 1122961:PTO_RS02750
uniprot id: Q6L1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1122961:PTO RS07560
gene id: 1122961:PTO_RS07560
uniprot id: Q6KZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1122961:PTO RS06655
gene id: 1122961:PTO_RS06655
uniprot id: Q6KZJ8
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS01240
gene id: 1122961:PTO_RS01240
uniprot id: Q6L2H7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

1122961:PTO RS01095
gene id: 1122961:PTO_RS01095
uniprot id: Q6L2K5
names: Similarity
messages: Belongs to the UPF0284 family.

1122961:PTO RS03860
gene id: 1122961:PTO_RS03860
uniprot id: Q6L135
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1122961:PTO RS03430
gene id: 1122961:PTO_RS03430
uniprot id: A0A8G2L6V7
uniprot id: Q6L1B9
names: Caution
names: Similarity
messages: Belongs to the SUI1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03670
gene id: 1122961:PTO_RS03670
uniprot id: A0A8G2L6Y7
uniprot id: Q6L174
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05160
gene id: 1122961:PTO_RS05160
uniprot id: Q6L0E0
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS04620
gene id: 1122961:PTO_RS04620
uniprot id: A0A8G2FVF9
uniprot id: Q6L0P2
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02780
gene id: 1122961:PTO_RS02780
uniprot id: Q6L1N9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1122961:PTO RS02660
gene id: 1122961:PTO_RS02660
uniprot id: Q6L1R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1122961:PTO RS05220
gene id: 1122961:PTO_RS05220
uniprot id: Q6L0C8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1122961:PTO RS05780
gene id: 1122961:PTO_RS05780
uniprot id: Q6L017
names: Similarity
messages: Belongs to the peptidase M20A family.

1122961:PTO RS00455
gene id: 1122961:PTO_RS00455
uniprot id: Q6L2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS01280
gene id: 1122961:PTO_RS01280
uniprot id: Q6L2H0
names: Similarity
messages: Belongs to the peptidase S66 family.

1122961:PTO RS07530
gene id: 1122961:PTO_RS07530
uniprot id: Q6KZ23
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

1122961:PTO RS06030
gene id: 1122961:PTO_RS06030
uniprot id: Q6KZW8
names: Similarity
messages: Belongs to the pirin family.

1122961:PTO RS06525
gene id: 1122961:PTO_RS06525
uniprot id: Q6KZM3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1122961:PTO RS02465
gene id: 1122961:PTO_RS02465
uniprot id: Q6L1V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1122961:PTO RS07475
gene id: 1122961:PTO_RS07475
uniprot id: Q6KZ34
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1122961:PTO RS07635
gene id: 1122961:PTO_RS07635
uniprot id: Q6KZ04
names: Similarity
messages: Belongs to the glutamate synthase family.

1122961:PTO RS03125
gene id: 1122961:PTO_RS03125
uniprot id: Q6L1H5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.

1122961:PTO RS06675
gene id: 1122961:PTO_RS06675
uniprot id: Q6KZJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1122961:PTO RS03040
gene id: 1122961:PTO_RS03040
uniprot id: Q6L1I8
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS07205
gene id: 1122961:PTO_RS07205
uniprot id: A0A8G2FWU4
uniprot id: Q6KZ89
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02525
gene id: 1122961:PTO_RS02525
uniprot id: Q6L1T9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the mevalonate 3,5-bisphosphate decarboxylase family.
messages: Catalyzes the ATP-independent decarboxylation of (R)-mevalonate 3,5-bisphosphate to isopentenyl phosphate. Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3-phosphate rather than mevalonate 5-phosphate. Shows no detectable decarboxylase activity on mevalonate, mevalonate 3-phosphate, mevalonate 5-phosphate or mevalonate 5-pyrophosphate.
messages: Homodimer.
messages: It is proposed that Thermoplasmatales adapted the classical archaeal mevalonate pathway by replacing mevalonate 5-phosphate decarboxylase (MMD) with two specialized enzymes (mevalonate-3-phosphate 5-kinase and mevalonate 3,5-bisphosphate decarboxylase) in order to produce isoprenoids in extremely acidic environments. It was found that at low pH, the dual function enzyme MMD is unable to carry out the first phosphorylation step, yet retains its ability to perform decarboxylation.

1122961:PTO RS05765
gene id: 1122961:PTO_RS05765
uniprot id: Q6L020
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS03530
gene id: 1122961:PTO_RS03530
uniprot id: Q6L1A0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1122961:PTO RS06415
gene id: 1122961:PTO_RS06415
uniprot id: A0A8G2L870
uniprot id: Q6KZP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS01075
gene id: 1122961:PTO_RS01075
uniprot id: Q6L2K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1122961:PTO RS06040
gene id: 1122961:PTO_RS06040
uniprot id: A0A8G2FXR7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS07685
gene id: 1122961:PTO_RS07685
uniprot id: A0A8G2L808
names: Caution
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03480
gene id: 1122961:PTO_RS03480
uniprot id: A0A8G2FVV3
uniprot id: Q6L1B0
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS06080
gene id: 1122961:PTO_RS06080
uniprot id: Q6KZW1
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS06400
gene id: 1122961:PTO_RS06400
uniprot id: A0A8G2FXA4
uniprot id: Q6KZP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS06320
gene id: 1122961:PTO_RS06320
uniprot id: Q6KZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1122961:PTO RS07275
gene id: 1122961:PTO_RS07275
uniprot id: Q6KZ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS04530
gene id: 1122961:PTO_RS04530
uniprot id: Q6L0R1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1122961:PTO RS03465
gene id: 1122961:PTO_RS03465
uniprot id: A0A8G2FVW1
uniprot id: Q6L1B3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03385
gene id: 1122961:PTO_RS03385
uniprot id: Q6L1C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Binds 2 Zn(2+) ions per subunit. One of the zinc atoms is essential for catalytic activity while the other has a structural function.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.

1122961:PTO RS01050
gene id: 1122961:PTO_RS01050
uniprot id: Q6L2L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1122961:PTO RS02235
gene id: 1122961:PTO_RS02235
uniprot id: Q6L1Z5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1122961:PTO RS05665
gene id: 1122961:PTO_RS05665
uniprot id: Q6L041
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1122961:PTO RS03690
gene id: 1122961:PTO_RS03690
uniprot id: Q6L170
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

1122961:PTO RS03635
gene id: 1122961:PTO_RS03635
uniprot id: A0A8G2FVT4
uniprot id: Q6L181
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS01990
gene id: 1122961:PTO_RS01990
uniprot id: Q6L243
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

1122961:PTO RS02240
gene id: 1122961:PTO_RS02240
uniprot id: Q6L1Z4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1122961:PTO RS05735
gene id: 1122961:PTO_RS05735
uniprot id: Q6L026
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1122961:PTO RS04135
gene id: 1122961:PTO_RS04135
uniprot id: Q6L0Y5
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

1122961:PTO RS06715
gene id: 1122961:PTO_RS06715
uniprot id: A0A8G2L855
uniprot id: Q6KZI6
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00910
gene id: 1122961:PTO_RS00910
uniprot id: Q6L2P2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS01310
gene id: 1122961:PTO_RS01310
uniprot id: Q6L2G5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1122961:PTO RS03925
gene id: 1122961:PTO_RS03925
uniprot id: Q6L122
names: Similarity
messages: Belongs to the PurH family.

1122961:PTO RS07020
gene id: 1122961:PTO_RS07020
uniprot id: Q6KZC7
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1122961:PTO RS02810
gene id: 1122961:PTO_RS02810
uniprot id: A0A8G2FW60
uniprot id: Q6L1N3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02455
gene id: 1122961:PTO_RS02455
uniprot id: A0A8G2L738
uniprot id: Q6L1V2
names: Caution
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03415
gene id: 1122961:PTO_RS03415
uniprot id: Q6L1C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1122961:PTO RS00495
gene id: 1122961:PTO_RS00495
uniprot id: Q6L2X0
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS03395
gene id: 1122961:PTO_RS03395
uniprot id: Q6L1C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1122961:PTO RS03400
gene id: 1122961:PTO_RS03400
uniprot id: Q6L1C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1122961:PTO RS02790
gene id: 1122961:PTO_RS02790
uniprot id: Q6L1N7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1122961:PTO RS07375
gene id: 1122961:PTO_RS07375
uniprot id: Q6KZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1122961:PTO RS05480
gene id: 1122961:PTO_RS05480
uniprot id: Q6L078
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1122961:PTO RS03790
gene id: 1122961:PTO_RS03790
uniprot id: A0A8G2L7K0
uniprot id: Q6L150
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS04265
gene id: 1122961:PTO_RS04265
uniprot id: Q6L0W0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1122961:PTO RS07500
gene id: 1122961:PTO_RS07500
uniprot id: Q6KZ29
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1122961:PTO RS01820
gene id: 1122961:PTO_RS01820
uniprot id: Q6L272
names: Function
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1122961:PTO RS03545
gene id: 1122961:PTO_RS03545
uniprot id: A0A8G2FVX5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00975
gene id: 1122961:PTO_RS00975
uniprot id: Q6L2M8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

1122961:PTO RS04035
gene id: 1122961:PTO_RS04035
uniprot id: Q6L101
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS05455
gene id: 1122961:PTO_RS05455
uniprot id: Q6L083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS03685
gene id: 1122961:PTO_RS03685
uniprot id: Q6L171
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1122961:PTO RS06370
gene id: 1122961:PTO_RS06370
uniprot id: A0A8G2FX87
uniprot id: Q6KZQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS07820
gene id: 1122961:PTO_RS07820
uniprot id: Q6KYW5
names: Similarity
messages: Belongs to the TPP enzyme family.

1122961:PTO RS01705
gene id: 1122961:PTO_RS01705
uniprot id: Q6L294
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1122961:PTO RS02205
gene id: 1122961:PTO_RS02205
uniprot id: A0A8G2FWD4
uniprot id: Q6L201
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00565
gene id: 1122961:PTO_RS00565
uniprot id: Q3V8B2
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1122961:PTO RS06515
gene id: 1122961:PTO_RS06515
uniprot id: Q6KZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formiminotransferase family.
messages: Catalyzes the transfer of the formyl group from N-formylglutamate to tetrahydrofolate (THF) to yield 5-formyltetrahydrofolate (5-CHO-THF) and glutamate (Glu). The triglutamate form of 5-CHO-THF (5-CHO-THF-Glu3) can also be used as substrate. It can also catalyzes the transfer of the formimino group from N-formiminoglutamate to tetrahydrofolate (THF) to yield 5-formiminotetrahydrofolate (5-NH=CH-THF) and glutamate (Glu). It can replace YgfA to catalyzes the irreversible ATP-dependent transformation of 5-CHO-THF to form 5,10-methenyltetrahydrofolate (5,10-CH=THF).
messages: Cytoplasm

1122961:PTO RS02160
gene id: 1122961:PTO_RS02160
uniprot id: Q6L210
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1122961:PTO RS07690
gene id: 1122961:PTO_RS07690
uniprot id: Q6KYZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS03490
gene id: 1122961:PTO_RS03490
uniprot id: Q6L1A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1122961:PTO RS05860
gene id: 1122961:PTO_RS05860
uniprot id: Q6L001
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1122961:PTO RS04495
gene id: 1122961:PTO_RS04495
uniprot id: Q6L0R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1122961:PTO RS03100
gene id: 1122961:PTO_RS03100
uniprot id: A0A8G2L7P5
uniprot id: Q6L1I0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS07165
gene id: 1122961:PTO_RS07165
uniprot id: Q6KZ98
names: Similarity
messages: Belongs to the 4HPPD family.

1122961:PTO RS01215
gene id: 1122961:PTO_RS01215
uniprot id: Q6L2I2
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

1122961:PTO RS06465
gene id: 1122961:PTO_RS06465
uniprot id: Q6KZN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1122961:PTO RS02045
gene id: 1122961:PTO_RS02045
uniprot id: Q6L232
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1122961:PTO RS01225
gene id: 1122961:PTO_RS01225
uniprot id: A0A8G2FY04
uniprot id: Q6L2I0
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05565
gene id: 1122961:PTO_RS05565
uniprot id: Q6L061
names: Similarity
messages: Belongs to the MoaD family.

1122961:PTO RS02855
gene id: 1122961:PTO_RS02855
uniprot id: Q6L1M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1122961:PTO RS01185
gene id: 1122961:PTO_RS01185
uniprot id: Q6L2I8
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

1122961:PTO RS07380
gene id: 1122961:PTO_RS07380
uniprot id: Q6KZ53
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

1122961:PTO RS01265
gene id: 1122961:PTO_RS01265
uniprot id: Q6L2H3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1122961:PTO RS03660
gene id: 1122961:PTO_RS03660
uniprot id: A0A8G2L6T9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS07585
gene id: 1122961:PTO_RS07585
uniprot id: Q6KZ13
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1122961:PTO RS01460
gene id: 1122961:PTO_RS01460
uniprot id: Q6L2D9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1122961:PTO RS02305
gene id: 1122961:PTO_RS02305
uniprot id: Q6L1Y1
names: Similarity
messages: Belongs to the ComB family.

1122961:PTO RS01815
gene id: 1122961:PTO_RS01815
uniprot id: Q6L273
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

1122961:PTO RS01480
gene id: 1122961:PTO_RS01480
uniprot id: Q6L2D5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1122961:PTO RS02720
gene id: 1122961:PTO_RS02720
uniprot id: A0A8G2FW50
uniprot id: Q6L1Q1
names: Caution
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02800
gene id: 1122961:PTO_RS02800
uniprot id: Q6L1N5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1122961:PTO RS01785
gene id: 1122961:PTO_RS01785
uniprot id: Q6L279
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS07775
gene id: 1122961:PTO_RS07775
uniprot id: Q6KYX4
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS03775
gene id: 1122961:PTO_RS03775
uniprot id: A0A8G2FVT6
uniprot id: Q6L153
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05340
gene id: 1122961:PTO_RS05340
uniprot id: Q6L0A5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1122961:PTO RS04295
gene id: 1122961:PTO_RS04295
uniprot id: Q6L0V5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1122961:PTO RS01350
gene id: 1122961:PTO_RS01350
uniprot id: Q6L2F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1122961:PTO RS02190
gene id: 1122961:PTO_RS02190
uniprot id: A0A8G2L788
uniprot id: Q6L204
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00655
gene id: 1122961:PTO_RS00655
uniprot id: Q6L2T9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1122961:PTO RS07780
gene id: 1122961:PTO_RS07780
uniprot id: Q6KYX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS05995
gene id: 1122961:PTO_RS05995
uniprot id: Q6KZX4
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1122961:PTO RS00940
gene id: 1122961:PTO_RS00940
uniprot id: Q6L2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1122961:PTO RS07215
gene id: 1122961:PTO_RS07215
uniprot id: Q6KZ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

1122961:PTO RS01755
gene id: 1122961:PTO_RS01755
uniprot id: Q6L285
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family. Glyceraldehyde dehydrogenase subfamily.
messages: Homotetramer (By similarity). Dimer of dimers.
messages: NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes.
messages: Stable for 2 hours at 60 degrees Celsius but activity is decreased to less than 50 percent within 15 minutes at 70 degrees Celsius.

1122961:PTO RS00425
gene id: 1122961:PTO_RS00425
uniprot id: Q6L2Y3
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS04515
gene id: 1122961:PTO_RS04515
uniprot id: A0A8G2L6M8
uniprot id: Q6L0R4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1122961:PTO RS02970
gene id: 1122961:PTO_RS02970
uniprot id: Q6L1K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1122961:PTO RS03650
gene id: 1122961:PTO_RS03650
uniprot id: A0A8G2L7K5
uniprot id: Q6L178
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1122961:PTO RS06460
gene id: 1122961:PTO_RS06460
uniprot id: Q6KZN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1122961:PTO RS05245
gene id: 1122961:PTO_RS05245
uniprot id: A0A8G2FXE9
uniprot id: Q6L0C3
names: Caution
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05425
gene id: 1122961:PTO_RS05425
uniprot id: Q6L088
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1122961:PTO RS05120
gene id: 1122961:PTO_RS05120
uniprot id: Q6L0E8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).

1122961:PTO RS06375
gene id: 1122961:PTO_RS06375
uniprot id: Q6KZQ2
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS07660
gene id: 1122961:PTO_RS07660
uniprot id: Q6KYZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

1122961:PTO RS04470
gene id: 1122961:PTO_RS04470
uniprot id: Q6L0S3
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS03305
gene id: 1122961:PTO_RS03305
uniprot id: A0A8G2FVX7
uniprot id: Q6L1E3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS07885
gene id: 1122961:PTO_RS07885
uniprot id: Q6KYV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1122961:PTO RS05180
gene id: 1122961:PTO_RS05180
uniprot id: Q6L0D6
names: Similarity
messages: Belongs to the peptidase M24B family.

1122961:PTO RS03165
gene id: 1122961:PTO_RS03165
uniprot id: Q6L1G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1122961:PTO RS06855
gene id: 1122961:PTO_RS06855
uniprot id: Q6KZF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1122961:PTO RS04915
gene id: 1122961:PTO_RS04915
uniprot id: Q6L0I7
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS06955
gene id: 1122961:PTO_RS06955
uniprot id: Q6KZD9
names: Similarity
messages: Belongs to the UPF0111 family.

1122961:PTO RS04830
gene id: 1122961:PTO_RS04830
uniprot id: Q6L0K4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1122961:PTO RS02080
gene id: 1122961:PTO_RS02080
uniprot id: Q6L225
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1122961:PTO RS05595
gene id: 1122961:PTO_RS05595
uniprot id: Q6L055
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1122961:PTO RS00245
gene id: 1122961:PTO_RS00245
uniprot id: Q6L316
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

1122961:PTO RS02145
gene id: 1122961:PTO_RS02145
uniprot id: A0A8G2FWE8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03315
gene id: 1122961:PTO_RS03315
uniprot id: Q6L1E1
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1122961:PTO RS02115
gene id: 1122961:PTO_RS02115
uniprot id: A0A8G2L793
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03175
gene id: 1122961:PTO_RS03175
uniprot id: Q6L1G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

1122961:PTO RS05440
gene id: 1122961:PTO_RS05440
uniprot id: Q6L086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS06725
gene id: 1122961:PTO_RS06725
uniprot id: A0A8G2L7G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00250
gene id: 1122961:PTO_RS00250
uniprot id: Q6L315
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

1122961:PTO RS02180
gene id: 1122961:PTO_RS02180
uniprot id: Q6L206
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1122961:PTO RS06890
gene id: 1122961:PTO_RS06890
uniprot id: A0A8G2FX12
uniprot id: Q6KZF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS08090
gene id: 1122961:PTO_RS08090
uniprot id: Q6L0J8
names: Similarity
messages: Belongs to the Nudix hydrolase family.
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1122961:PTO RS06420
gene id: 1122961:PTO_RS06420
uniprot id: Q6KZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1122961:PTO RS07865
gene id: 1122961:PTO_RS07865
uniprot id: Q6KYV6
names: Similarity
messages: Belongs to the peptidase S45 family.

1122961:PTO RS06565
gene id: 1122961:PTO_RS06565
uniprot id: A0A8G2L863
uniprot id: Q6KZL5
names: Caution
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00900
gene id: 1122961:PTO_RS00900
uniprot id: A0A8G2FXW9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03280
gene id: 1122961:PTO_RS03280
uniprot id: Q6L1E7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1122961:PTO RS04585
gene id: 1122961:PTO_RS04585
uniprot id: Q6L0P9
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

1122961:PTO RS03445
gene id: 1122961:PTO_RS03445
uniprot id: A0A8G2FVY7
uniprot id: Q6L1B7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS01380
gene id: 1122961:PTO_RS01380
uniprot id: Q6L2F3
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1122961:PTO RS02280
gene id: 1122961:PTO_RS02280
uniprot id: A0A8G2FWC5
uniprot id: Q6L1Y6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS04520
gene id: 1122961:PTO_RS04520
uniprot id: A0A8G2FVJ8
uniprot id: Q6L0R3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02700
gene id: 1122961:PTO_RS02700
uniprot id: Q6L1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1122961:PTO RS02615
gene id: 1122961:PTO_RS02615
uniprot id: Q6L1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

1122961:PTO RS00865
gene id: 1122961:PTO_RS00865
uniprot id: Q6L2P9
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1122961:PTO RS06475
gene id: 1122961:PTO_RS06475
uniprot id: Q6KZN3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1122961:PTO RS06275
gene id: 1122961:PTO_RS06275
uniprot id: Q6KZS2
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1122961:PTO RS03520
gene id: 1122961:PTO_RS03520
uniprot id: Q6L1A2
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS03320
gene id: 1122961:PTO_RS03320
uniprot id: Q6L1E0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1122961:PTO RS04475
gene id: 1122961:PTO_RS04475
uniprot id: Q6L0S2
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

1122961:PTO RS02050
gene id: 1122961:PTO_RS02050
uniprot id: Q6L231
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS01285
gene id: 1122961:PTO_RS01285
uniprot id: Q6L2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

1122961:PTO RS07520
gene id: 1122961:PTO_RS07520
uniprot id: Q6KZ25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycerate kinase type-1 family.
messages: Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate. It can also partially utilize GTP, CTP or UTP as phosphate donor.
messages: Homodimer.
messages: Magnesium. It could be replaced to some extent by nickel, manganese or cobalt.

1122961:PTO RS01340
gene id: 1122961:PTO_RS01340
uniprot id: Q6L2F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1122961:PTO RS06970
gene id: 1122961:PTO_RS06970
uniprot id: Q6KZD6
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1122961:PTO RS02485
gene id: 1122961:PTO_RS02485
uniprot id: Q6L1U7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1122961:PTO RS05325
gene id: 1122961:PTO_RS05325
uniprot id: Q6L0A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.

1122961:PTO RS02595
gene id: 1122961:PTO_RS02595
uniprot id: Q6L1S5
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1122961:PTO RS04175
gene id: 1122961:PTO_RS04175
uniprot id: Q6L0X7
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS04105
gene id: 1122961:PTO_RS04105
uniprot id: Q6L0Z1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1122961:PTO RS04180
gene id: 1122961:PTO_RS04180
uniprot id: Q6L0X6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1122961:PTO RS04795
gene id: 1122961:PTO_RS04795
uniprot id: Q6L0L1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1122961:PTO RS07905
gene id: 1122961:PTO_RS07905
uniprot id: Q6KYU8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1122961:PTO RS07010
gene id: 1122961:PTO_RS07010
uniprot id: Q6KZC9
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1122961:PTO RS00660
gene id: 1122961:PTO_RS00660
uniprot id: A0A8G2FXY2
uniprot id: Q6L2T8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00985
gene id: 1122961:PTO_RS00985
uniprot id: Q6L2M6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS02230
gene id: 1122961:PTO_RS02230
uniprot id: Q6L1Z6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1122961:PTO RS06535
gene id: 1122961:PTO_RS06535
uniprot id: Q6KZM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1122961:PTO RS06850
gene id: 1122961:PTO_RS06850
uniprot id: Q6KZG0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

1122961:PTO RS00335
gene id: 1122961:PTO_RS00335
uniprot id: Q6L2Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1122961:PTO RS01120
gene id: 1122961:PTO_RS01120
uniprot id: Q6L2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1122961:PTO RS05950
gene id: 1122961:PTO_RS05950
uniprot id: Q6KZY3
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS01335
gene id: 1122961:PTO_RS01335
uniprot id: Q6L2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

1122961:PTO RS06590
gene id: 1122961:PTO_RS06590
uniprot id: A0A8G2L7K3
uniprot id: Q6KZL0
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03185
gene id: 1122961:PTO_RS03185
uniprot id: Q6L1G4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1122961:PTO RS01825
gene id: 1122961:PTO_RS01825
uniprot id: Q6L271
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1122961:PTO RS03540
gene id: 1122961:PTO_RS03540
uniprot id: Q6L198
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1122961:PTO RS01315
gene id: 1122961:PTO_RS01315
uniprot id: A0A8G2FY63
uniprot id: Q6L2G4
names: Caution
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02560
gene id: 1122961:PTO_RS02560
uniprot id: Q6L1T2
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GaD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Constitutively expressed.
messages: Homooctamer.
messages: Involved in the degradation of glucose and galactose via the nonphosphorylative variant of Entner-Doudoroff pathway. Catalyzes the dehydration of gluconate to produce 2-keto-3-deoxygluconate (KDG). It is also able to catalyze the dehydration of galactonate to produce 2-keto-3-deoxygalactonate (KDGal).

1122961:PTO RS02540
gene id: 1122961:PTO_RS02540
uniprot id: Q6L1T6
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

1122961:PTO RS04755
gene id: 1122961:PTO_RS04755
uniprot id: Q6L0L9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1122961:PTO RS02550
gene id: 1122961:PTO_RS02550
uniprot id: Q6L1T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS04990
gene id: 1122961:PTO_RS04990
uniprot id: Q6L0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1122961:PTO RS02995
gene id: 1122961:PTO_RS02995
uniprot id: Q6L1J7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1122961:PTO RS03115
gene id: 1122961:PTO_RS03115
uniprot id: Q6L1H7
names: Similarity
messages: Belongs to the carbamate kinase family.

1122961:PTO RS04735
gene id: 1122961:PTO_RS04735
uniprot id: Q6L0M3
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1122961:PTO RS01470
gene id: 1122961:PTO_RS01470
uniprot id: Q6L2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

1122961:PTO RS02245
gene id: 1122961:PTO_RS02245
uniprot id: Q6L1Z3
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS06795
gene id: 1122961:PTO_RS06795
uniprot id: Q6KZH0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1122961:PTO RS07385
gene id: 1122961:PTO_RS07385
uniprot id: Q6KZ52
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1122961:PTO RS00430
gene id: 1122961:PTO_RS00430
uniprot id: Q6L2Y2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS07090
gene id: 1122961:PTO_RS07090
uniprot id: Q6KZB4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1122961:PTO RS02155
gene id: 1122961:PTO_RS02155
uniprot id: Q6L211
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1122961:PTO RS04445
gene id: 1122961:PTO_RS04445
uniprot id: Q6L0S7
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1122961:PTO RS07960
gene id: 1122961:PTO_RS07960
uniprot id: Q6KYT8
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS00235
gene id: 1122961:PTO_RS00235
uniprot id: Q6L318
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1122961:PTO RS04380
gene id: 1122961:PTO_RS04380
uniprot id: Q6L0T9
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS01030
gene id: 1122961:PTO_RS01030
uniprot id: Q6L2L8
names: Similarity
messages: Belongs to the UPF0147 family.

1122961:PTO RS01775
gene id: 1122961:PTO_RS01775
uniprot id: Q6L281
names: Similarity
messages: Belongs to the pyruvate kinase family.

1122961:PTO RS05670
gene id: 1122961:PTO_RS05670
uniprot id: Q6L040
names: Similarity
messages: Belongs to the peptidase C56 family.

1122961:PTO RS04675
gene id: 1122961:PTO_RS04675
uniprot id: A0A8G2FVH3
uniprot id: Q6L0N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02345
gene id: 1122961:PTO_RS02345
uniprot id: Q6L1X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1122961:PTO RS05315
gene id: 1122961:PTO_RS05315
uniprot id: Q6L0A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1122961:PTO RS01255
gene id: 1122961:PTO_RS01255
uniprot id: Q6L2H4
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS03525
gene id: 1122961:PTO_RS03525
uniprot id: Q6L1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

1122961:PTO RS06845
gene id: 1122961:PTO_RS06845
uniprot id: Q6KZG1
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 2 family.

1122961:PTO RS06290
gene id: 1122961:PTO_RS06290
uniprot id: Q6KZR9
names: Similarity
messages: Belongs to the arsA ATPase family.

1122961:PTO RS01810
gene id: 1122961:PTO_RS01810
uniprot id: Q6L274
names: Similarity
messages: Belongs to the TrpF family.

1122961:PTO RS05980
gene id: 1122961:PTO_RS05980
uniprot id: Q6KZX7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS01980
gene id: 1122961:PTO_RS01980
uniprot id: Q6L245
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1122961:PTO RS02535
gene id: 1122961:PTO_RS02535
uniprot id: Q6L1T7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1122961:PTO RS04690
gene id: 1122961:PTO_RS04690
uniprot id: Q6L0N0
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1122961:PTO RS07455
gene id: 1122961:PTO_RS07455
uniprot id: Q6KZ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity).
messages: In the C-terminal section; belongs to the endonuclease V family.
messages: In the N-terminal section; belongs to the MGMT family.

1122961:PTO RS06900
gene id: 1122961:PTO_RS06900
uniprot id: Q6KZF0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1122961:PTO RS05470
gene id: 1122961:PTO_RS05470
uniprot id: Q6L080
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1122961:PTO RS05615
gene id: 1122961:PTO_RS05615
uniprot id: Q6L051
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1122961:PTO RS04980
gene id: 1122961:PTO_RS04980
uniprot id: Q6L0H5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1122961:PTO RS02085
gene id: 1122961:PTO_RS02085
uniprot id: Q6L224
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1122961:PTO RS02210
gene id: 1122961:PTO_RS02210
uniprot id: A0A8G2FWB2
uniprot id: Q6L200
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS04500
gene id: 1122961:PTO_RS04500
uniprot id: Q6L0R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

1122961:PTO RS04740
gene id: 1122961:PTO_RS04740
uniprot id: Q6L0M2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1122961:PTO RS00435
gene id: 1122961:PTO_RS00435
uniprot id: Q6L2Y1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1122961:PTO RS03405
gene id: 1122961:PTO_RS03405
uniprot id: A0A8G2FVW0
uniprot id: Q6L1C4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05570
gene id: 1122961:PTO_RS05570
uniprot id: Q6L060
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS02580
gene id: 1122961:PTO_RS02580
uniprot id: Q6L1S8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

1122961:PTO RS00715
gene id: 1122961:PTO_RS00715
uniprot id: Q6L2S8
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS05105
gene id: 1122961:PTO_RS05105
uniprot id: A0A8G2FX90
uniprot id: Q6L0F1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS06885
gene id: 1122961:PTO_RS06885
uniprot id: Q6KZF2
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1122961:PTO RS07670
gene id: 1122961:PTO_RS07670
uniprot id: Q6KYZ7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1122961:PTO RS02880
gene id: 1122961:PTO_RS02880
uniprot id: Q6L1M0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1122961:PTO RS02325
gene id: 1122961:PTO_RS02325
uniprot id: Q6L1X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1122961:PTO RS06740
gene id: 1122961:PTO_RS06740
uniprot id: A0A8G2L7J3
uniprot id: Q6KZI1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02065
gene id: 1122961:PTO_RS02065
uniprot id: A0A8G2FWF7
uniprot id: Q6L228
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03855
gene id: 1122961:PTO_RS03855
uniprot id: Q6L137
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS03500
gene id: 1122961:PTO_RS03500
uniprot id: A0A8G2L6X5
uniprot id: Q6L1A6
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05205
gene id: 1122961:PTO_RS05205
uniprot id: Q6L0D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1122961:PTO RS06995
gene id: 1122961:PTO_RS06995
uniprot id: A0A8G2FX17
uniprot id: Q6KZD1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS04955
gene id: 1122961:PTO_RS04955
uniprot id: Q6L0I0
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS07310
gene id: 1122961:PTO_RS07310
uniprot id: Q6KZ67
names: Similarity
messages: Belongs to the complex I subunit 3 family.

1122961:PTO RS07350
gene id: 1122961:PTO_RS07350
uniprot id: Q6KZ59
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS01640
gene id: 1122961:PTO_RS01640
uniprot id: Q6L2A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1122961:PTO RS00555
gene id: 1122961:PTO_RS00555
uniprot id: Q6L2V8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1122961:PTO RS04590
gene id: 1122961:PTO_RS04590
uniprot id: A0A8G2L6M3
uniprot id: Q6L0P8
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02515
gene id: 1122961:PTO_RS02515
uniprot id: Q6L1U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1122961:PTO RS07720
gene id: 1122961:PTO_RS07720
uniprot id: Q6KYY5
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

1122961:PTO RS07330
gene id: 1122961:PTO_RS07330
uniprot id: Q6KZ63
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS03770
gene id: 1122961:PTO_RS03770
uniprot id: Q6L154
names: Similarity
messages: Belongs to the DMRL synthase family.

1122961:PTO RS03310
gene id: 1122961:PTO_RS03310
uniprot id: A0A8G2FVY4
uniprot id: Q6L1E2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03085
gene id: 1122961:PTO_RS03085
uniprot id: Q6L1I2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1122961:PTO RS03485
gene id: 1122961:PTO_RS03485
uniprot id: Q6L1A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1122961:PTO RS07680
gene id: 1122961:PTO_RS07680
uniprot id: Q6KYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.

1122961:PTO RS05680
gene id: 1122961:PTO_RS05680
uniprot id: Q6L038
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1122961:PTO RS04250
gene id: 1122961:PTO_RS04250
uniprot id: A0A8G2FVM7
uniprot id: Q6L0W3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS04505
gene id: 1122961:PTO_RS04505
uniprot id: Q6L0R6
names: Similarity
messages: Belongs to the UPF0179 family.

1122961:PTO RS00805
gene id: 1122961:PTO_RS00805
uniprot id: Q6L2R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1122961:PTO RS05195
gene id: 1122961:PTO_RS05195
uniprot id: Q6L0D3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1122961:PTO RS06300
gene id: 1122961:PTO_RS06300
uniprot id: A0A8G2FXA0
uniprot id: Q6KZR7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS06620
gene id: 1122961:PTO_RS06620
uniprot id: A0A8G2FX24
uniprot id: Q6KZK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS01965
gene id: 1122961:PTO_RS01965
uniprot id: Q6L248
names: Similarity
messages: Belongs to the glutaredoxin family.

1122961:PTO RS07595
gene id: 1122961:PTO_RS07595
uniprot id: Q6KZ11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1122961:PTO RS00545
gene id: 1122961:PTO_RS00545
uniprot id: Q6L2W0
names: Similarity
messages: Belongs to the arginase family.

1122961:PTO RS01290
gene id: 1122961:PTO_RS01290
uniprot id: Q6L2G8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1122961:PTO RS01275
gene id: 1122961:PTO_RS01275
uniprot id: Q6L2H1
names: Similarity
messages: Belongs to the peptidase M20A family.

1122961:PTO RS04640
gene id: 1122961:PTO_RS04640
uniprot id: Q6L0N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

1122961:PTO RS07970
gene id: 1122961:PTO_RS07970
uniprot id: Q6KYT6
names: Similarity
messages: Belongs to the sterol desaturase family.

1122961:PTO RS02815
gene id: 1122961:PTO_RS02815
uniprot id: Q6L1N2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1122961:PTO RS06075
gene id: 1122961:PTO_RS06075
uniprot id: Q6KZW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

1122961:PTO RS07430
gene id: 1122961:PTO_RS07430
uniprot id: Q6KZ43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1122961:PTO RS07675
gene id: 1122961:PTO_RS07675
uniprot id: Q6KYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).

1122961:PTO RS01125
gene id: 1122961:PTO_RS01125
uniprot id: A0A8G2FXX0
uniprot id: Q6L2J9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS08065
gene id: 1122961:PTO_RS08065
uniprot id: A0A8G2FW79
uniprot id: Q6L1P9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00725
gene id: 1122961:PTO_RS00725
uniprot id: Q6L2S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1122961:PTO RS03005
gene id: 1122961:PTO_RS03005
uniprot id: Q6L1J5
names: Subcellular Location Annotation
messages: Cell membrane

1122961:PTO RS00475
gene id: 1122961:PTO_RS00475
uniprot id: Q6L2X4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1122961:PTO RS04745
gene id: 1122961:PTO_RS04745
uniprot id: A0A8G2L7D4
uniprot id: Q6L0M1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03920
gene id: 1122961:PTO_RS03920
uniprot id: Q6L123
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1122961:PTO RS07270
gene id: 1122961:PTO_RS07270
uniprot id: Q6KZ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS05400
gene id: 1122961:PTO_RS05400
uniprot id: Q6L093
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1122961:PTO RS06975
gene id: 1122961:PTO_RS06975
uniprot id: Q6KZD5
names: Similarity
messages: Belongs to the HisA/HisF family.

1122961:PTO RS03815
gene id: 1122961:PTO_RS03815
uniprot id: Q6L146
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1122961:PTO RS01360
gene id: 1122961:PTO_RS01360
uniprot id: Q6L2F6
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1122961:PTO RS06255
gene id: 1122961:PTO_RS06255
uniprot id: Q6KZS6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1122961:PTO RS06410
gene id: 1122961:PTO_RS06410
uniprot id: A0A8G2FX81
uniprot id: Q6KZP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00870
gene id: 1122961:PTO_RS00870
uniprot id: Q6L2P8
names: Similarity
messages: Belongs to the citrate synthase family.

1122961:PTO RS00700
gene id: 1122961:PTO_RS00700
uniprot id: Q6L2T1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1122961:PTO RS07930
gene id: 1122961:PTO_RS07930
uniprot id: A0A8G2L783
uniprot id: Q6KYU3
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05935
gene id: 1122961:PTO_RS05935
uniprot id: Q6KZY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1122961:PTO RS04240
gene id: 1122961:PTO_RS04240
uniprot id: Q6L0W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).

1122961:PTO RS01345
gene id: 1122961:PTO_RS01345
uniprot id: Q6L2F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1122961:PTO RS00850
gene id: 1122961:PTO_RS00850
uniprot id: Q6L2Q2
names: Similarity
messages: Belongs to the UbiD family.

1122961:PTO RS03905
gene id: 1122961:PTO_RS03905
uniprot id: Q6L126
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

1122961:PTO RS07555
gene id: 1122961:PTO_RS07555
uniprot id: Q6KZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1122961:PTO RS01070
gene id: 1122961:PTO_RS01070
uniprot id: A0A8G2FY54
uniprot id: Q6L2L0
names: Caution
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03180
gene id: 1122961:PTO_RS03180
uniprot id: Q6L1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1122961:PTO RS01130
gene id: 1122961:PTO_RS01130
uniprot id: Q6L2J8
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

1122961:PTO RS02320
gene id: 1122961:PTO_RS02320
uniprot id: Q6L1X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1122961:PTO RS01710
gene id: 1122961:PTO_RS01710
uniprot id: A0A8G2L7Y1
uniprot id: Q6L293
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03420
gene id: 1122961:PTO_RS03420
uniprot id: Q6L1C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1122961:PTO RS08105
gene id: 1122961:PTO_RS08105
uniprot id: Q6L0D5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

1122961:PTO RS06670
gene id: 1122961:PTO_RS06670
uniprot id: A0A8G2FX40
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS06835
gene id: 1122961:PTO_RS06835
uniprot id: Q6KZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1122961:PTO RS03610
gene id: 1122961:PTO_RS03610
uniprot id: Q6L186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1122961:PTO RS01065
gene id: 1122961:PTO_RS01065
uniprot id: Q6L2L1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

1122961:PTO RS04390
gene id: 1122961:PTO_RS04390
uniprot id: Q6L0T7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1122961:PTO RS06950
gene id: 1122961:PTO_RS06950
uniprot id: Q6KZE0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

1122961:PTO RS01795
gene id: 1122961:PTO_RS01795
uniprot id: Q6L277
names: Similarity
messages: Belongs to the TrpC family.

1122961:PTO RS05600
gene id: 1122961:PTO_RS05600
uniprot id: Q6L054
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS04305
gene id: 1122961:PTO_RS04305
uniprot id: Q6L0V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1122961:PTO RS00860
gene id: 1122961:PTO_RS00860
uniprot id: Q6L2Q0
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS06245
gene id: 1122961:PTO_RS06245
uniprot id: Q6KZS8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1122961:PTO RS04550
gene id: 1122961:PTO_RS04550
uniprot id: Q6L0Q7
names: Similarity
messages: Belongs to the peptidase U62 family.

1122961:PTO RS02680
gene id: 1122961:PTO_RS02680
uniprot id: Q6L1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1122961:PTO RS00770
gene id: 1122961:PTO_RS00770
uniprot id: Q6L2R8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1122961:PTO RS03440
gene id: 1122961:PTO_RS03440
uniprot id: A0A8G2L704
uniprot id: Q6L1B8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS04345
gene id: 1122961:PTO_RS04345
uniprot id: A0A8G2L7G1
uniprot id: Q6L0U7
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03455
gene id: 1122961:PTO_RS03455
uniprot id: Q6L1B5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1122961:PTO RS02705
gene id: 1122961:PTO_RS02705
uniprot id: Q6L1Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1122961:PTO RS08150
gene id: 1122961:PTO_RS08150
uniprot id: Q6KZ32
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1122961:PTO RS03765
gene id: 1122961:PTO_RS03765
uniprot id: Q6L155
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1122961:PTO RS06130
gene id: 1122961:PTO_RS06130
uniprot id: Q6KZV0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1122961:PTO RS07650
gene id: 1122961:PTO_RS07650
uniprot id: Q6KZ01
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

1122961:PTO RS01235
gene id: 1122961:PTO_RS01235
uniprot id: Q6L2H8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

1122961:PTO RS00995
gene id: 1122961:PTO_RS00995
uniprot id: A0A8G2FY26
uniprot id: Q6L2M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS07290
gene id: 1122961:PTO_RS07290
uniprot id: Q6KZ71
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1122961:PTO RS07610
gene id: 1122961:PTO_RS07610
uniprot id: Q6KZ08
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1122961:PTO RS06865
gene id: 1122961:PTO_RS06865
uniprot id: Q6KZF6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1122961:PTO RS03245
gene id: 1122961:PTO_RS03245
uniprot id: Q6L1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.

1122961:PTO RS03355
gene id: 1122961:PTO_RS03355
uniprot id: Q6L1D3
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS02405
gene id: 1122961:PTO_RS02405
uniprot id: Q6L1W1
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1122961:PTO RS05155
gene id: 1122961:PTO_RS05155
uniprot id: Q6L0E1
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS04790
gene id: 1122961:PTO_RS04790
uniprot id: A0A8G2FVE0
uniprot id: Q6L0L2
names: Caution
names: Similarity
messages: Belongs to the UPF0215 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05070
gene id: 1122961:PTO_RS05070
uniprot id: A0A8G2FVB0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00530
gene id: 1122961:PTO_RS00530
uniprot id: Q6L2W3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS06755
gene id: 1122961:PTO_RS06755
uniprot id: Q6KZH8
names: Similarity
messages: Belongs to the HypE family.

1122961:PTO RS00340
gene id: 1122961:PTO_RS00340
uniprot id: Q6L2Z7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1122961:PTO RS03410
gene id: 1122961:PTO_RS03410
uniprot id: A0A8G2FVY2
uniprot id: Q6L1C3
names: Caution
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS06980
gene id: 1122961:PTO_RS06980
uniprot id: Q6KZD4
names: Similarity
messages: Belongs to the HisA/HisF family.

1122961:PTO RS02565
gene id: 1122961:PTO_RS02565
uniprot id: Q6L1T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1122961:PTO RS07740
gene id: 1122961:PTO_RS07740
uniprot id: Q6KYY1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1122961:PTO RS05870
gene id: 1122961:PTO_RS05870
uniprot id: Q6KZZ9
names: Similarity
messages: Belongs to the UPF0173 family.

1122961:PTO RS03910
gene id: 1122961:PTO_RS03910
uniprot id: Q6L125
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

1122961:PTO RS06530
gene id: 1122961:PTO_RS06530
uniprot id: Q6KZM2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1122961:PTO RS01200
gene id: 1122961:PTO_RS01200
uniprot id: Q6L2I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1122961:PTO RS05805
gene id: 1122961:PTO_RS05805
uniprot id: Q6L012
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1122961:PTO RS02590
gene id: 1122961:PTO_RS02590
uniprot id: Q6L1S6
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1122961:PTO RS07390
gene id: 1122961:PTO_RS07390
uniprot id: Q6KZ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1122961:PTO RS07140
gene id: 1122961:PTO_RS07140
uniprot id: Q6KZA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1122961:PTO RS06405
gene id: 1122961:PTO_RS06405
uniprot id: A0A8G2FX52
uniprot id: Q6KZP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: With S5 and S12 plays an important role in translational accuracy.

1122961:PTO RS01090
gene id: 1122961:PTO_RS01090
uniprot id: Q6L2K6
names: Similarity
messages: Belongs to the peptidase S49 family.

1122961:PTO RS05060
gene id: 1122961:PTO_RS05060
uniprot id: Q6L0F9
names: Similarity
messages: Belongs to the MEMO1 family.

1122961:PTO RS05305
gene id: 1122961:PTO_RS05305
uniprot id: Q6L0B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1122961:PTO RS01715
gene id: 1122961:PTO_RS01715
uniprot id: Q6L292
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1122961:PTO RS02095
gene id: 1122961:PTO_RS02095
uniprot id: A0A8G2L7W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02670
gene id: 1122961:PTO_RS02670
uniprot id: Q6L1R1
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

1122961:PTO RS04540
gene id: 1122961:PTO_RS04540
uniprot id: Q6L0Q9
names: Similarity
messages: Belongs to the SHMT family.

1122961:PTO RS06550
gene id: 1122961:PTO_RS06550
uniprot id: Q6KZL8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1122961:PTO RS03840
gene id: 1122961:PTO_RS03840
uniprot id: A0A8G2FVQ7
uniprot id: Q6L140
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1122961:PTO RS07830
gene id: 1122961:PTO_RS07830
uniprot id: Q6KYW3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1122961:PTO RS01995
gene id: 1122961:PTO_RS01995
uniprot id: Q6L242
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1122961:PTO RS01330
gene id: 1122961:PTO_RS01330
uniprot id: Q6L2G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1122961:PTO RS01700
gene id: 1122961:PTO_RS01700
uniprot id: Q6L295
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1122961:PTO RS03505
gene id: 1122961:PTO_RS03505
uniprot id: Q6L1A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1122961:PTO RS06250
gene id: 1122961:PTO_RS06250
uniprot id: Q6KZS7
names: Similarity
messages: Belongs to the archease family.

1122961:PTO RS04945
gene id: 1122961:PTO_RS04945
uniprot id: Q6L0I2
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1122961:PTO RS05200
gene id: 1122961:PTO_RS05200
uniprot id: Q6L0D2
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS00080
gene id: 1122961:PTO_RS00080
uniprot id: Q6L349
names: Similarity
messages: Belongs to the peptidase C40 family.

1122961:PTO RS05250
gene id: 1122961:PTO_RS05250
uniprot id: Q6L0C2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1122961:PTO RS05190
gene id: 1122961:PTO_RS05190
uniprot id: Q6L0D4
names: Subcellular Location Annotation
messages: Cytoplasm

1122961:PTO RS04490
gene id: 1122961:PTO_RS04490
uniprot id: Q6L0R9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1122961:PTO RS04935
gene id: 1122961:PTO_RS04935
uniprot id: Q6L0I4
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS00825
gene id: 1122961:PTO_RS00825
uniprot id: Q6L2Q7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane

1122961:PTO RS05080
gene id: 1122961:PTO_RS05080
uniprot id: A0A8G2FVA3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS01365
gene id: 1122961:PTO_RS01365
uniprot id: Q6L2F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS07105
gene id: 1122961:PTO_RS07105
uniprot id: Q6KZB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family.
messages: Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5-phosphate. Also able to catalyze the formation of isobutene via the conversion of 3-hydroxyisovalerate (3-HIV) to an unstable 3-phosphate intermediate that undergoes a spontaneous decarboxylation.
messages: Homodimer.

1122961:PTO RS04560
gene id: 1122961:PTO_RS04560
uniprot id: Q6L0Q5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1122961:PTO RS03780
gene id: 1122961:PTO_RS03780
uniprot id: A0A8G2FVR7
uniprot id: Q6L152
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS07890
gene id: 1122961:PTO_RS07890
uniprot id: Q6KYV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1122961:PTO RS02480
gene id: 1122961:PTO_RS02480
uniprot id: Q6L1U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1122961:PTO RS05820
gene id: 1122961:PTO_RS05820
uniprot id: Q6L009
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1122961:PTO RS02945
gene id: 1122961:PTO_RS02945
uniprot id: Q6L1K7
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1122961:PTO RS07725
gene id: 1122961:PTO_RS07725
uniprot id: Q6KYY4
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS06260
gene id: 1122961:PTO_RS06260
uniprot id: Q6KZS5
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

1122961:PTO RS06730
gene id: 1122961:PTO_RS06730
uniprot id: Q6KZI3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

1122961:PTO RS06785
gene id: 1122961:PTO_RS06785
uniprot id: Q6KZH2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1122961:PTO RS07315
gene id: 1122961:PTO_RS07315
uniprot id: Q6KZ66
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1122961:PTO RS03265
gene id: 1122961:PTO_RS03265
uniprot id: Q6L1F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Binds two Mg(2+) per subunit.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.

1122961:PTO RS05800
gene id: 1122961:PTO_RS05800
uniprot id: A0A8G2FXL9
uniprot id: Q6L013
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS03550
gene id: 1122961:PTO_RS03550
uniprot id: Q6L197
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1122961:PTO RS06295
gene id: 1122961:PTO_RS06295
uniprot id: Q6KZR8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1122961:PTO RS07625
gene id: 1122961:PTO_RS07625
uniprot id: Q6KZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1122961:PTO RS07300
gene id: 1122961:PTO_RS07300
uniprot id: Q6KZ69
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

1122961:PTO RS03510
gene id: 1122961:PTO_RS03510
uniprot id: Q6L1A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1122961:PTO RS03565
gene id: 1122961:PTO_RS03565
uniprot id: A0A8G2FVW4
uniprot id: Q6L195
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS02315
gene id: 1122961:PTO_RS02315
uniprot id: A0A8G2L7U9
uniprot id: Q6L1X9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05635
gene id: 1122961:PTO_RS05635
uniprot id: Q6L047
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Is also significantly active with D-galactose as substrate, but not with D-xylose, L-arabinose, D-ribose, D-mannose, D-allose, D-glucosamine, 2-deoxy-D-glucose, or glucose-6-phosphate. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+) (20-fold higher activity). Physiologically, may be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway.
messages: Homotetramer.
messages: Zn(2+) is of critical importance for the stability of the enzyme.

1122961:PTO RS04435
gene id: 1122961:PTO_RS04435
uniprot id: Q6L0S9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1122961:PTO RS06325
gene id: 1122961:PTO_RS06325
uniprot id: Q6KZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1122961:PTO RS03210
gene id: 1122961:PTO_RS03210
uniprot id: A0A8G2FW05
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS00695
gene id: 1122961:PTO_RS00695
uniprot id: A0A8G2FXV7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS01230
gene id: 1122961:PTO_RS01230
uniprot id: Q6L2H9
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1122961:PTO RS07005
gene id: 1122961:PTO_RS07005
uniprot id: A0A8G2L840
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS04910
gene id: 1122961:PTO_RS04910
uniprot id: Q6L0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1122961:PTO RS07450
gene id: 1122961:PTO_RS07450
uniprot id: Q6KZ39
names: Subcellular Location Annotation
messages: Membrane

1122961:PTO RS07465
gene id: 1122961:PTO_RS07465
uniprot id: Q6KZ36
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1122961:PTO RS02460
gene id: 1122961:PTO_RS02460
uniprot id: Q6L1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1122961:PTO RS02005
gene id: 1122961:PTO_RS02005
uniprot id: Q6L240
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1122961:PTO RS06910
gene id: 1122961:PTO_RS06910
uniprot id: Q6KZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1122961:PTO RS03205
gene id: 1122961:PTO_RS03205
uniprot id: Q6L1G0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1122961:PTO RS02655
gene id: 1122961:PTO_RS02655
uniprot id: Q6L1R4
names: Similarity
messages: Belongs to the GcvT family.

1122961:PTO RS05685
gene id: 1122961:PTO_RS05685
uniprot id: A0A8G2L8C5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1122961:PTO RS05285
gene id: 1122961:PTO_RS05285
uniprot id: Q6L0B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1122961:PTO RS03935
gene id: 1122961:PTO_RS03935
uniprot id: Q6L120
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1122961:PTO RS00880
gene id: 1122961:PTO_RS00880
uniprot id: Q6L2P6
names: Similarity
messages: Belongs to the PrpD family.

1122961:PTO RS02805
gene id: 1122961:PTO_RS02805
uniprot id: Q6L1N4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1122961:PTO RS03460
gene id: 1122961:PTO_RS03460
uniprot id: Q6L1B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1122961:PTO RS07835
gene id: 1122961:PTO_RS07835
uniprot id: Q6KYW2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.