1121362:A605 RS09290
gene id: 1121362:A605_RS09290
uniprot id: M1MYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1121362:A605 RS10515
gene id: 1121362:A605_RS10515
uniprot id: M1NUB6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1121362:A605 RS00705
gene id: 1121362:A605_RS00705
uniprot id: M1NIC1
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS06535
gene id: 1121362:A605_RS06535
uniprot id: M1NXS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1121362:A605 RS06705
gene id: 1121362:A605_RS06705
uniprot id: M1MX39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1121362:A605 RS08590
gene id: 1121362:A605_RS08590
uniprot id: M1MY87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS12595
gene id: 1121362:A605_RS12595
uniprot id: M1P132
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS13725
gene id: 1121362:A605_RS13725
uniprot id: M1P1K8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1121362:A605 RS02430
gene id: 1121362:A605_RS02430
uniprot id: M1NPT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121362:A605 RS11155
gene id: 1121362:A605_RS11155
uniprot id: M1P947
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121362:A605 RS02690
gene id: 1121362:A605_RS02690
uniprot id: M1NJI3
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1121362:A605 RS09330
gene id: 1121362:A605_RS09330
uniprot id: M1NTN7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1121362:A605 RS12720
gene id: 1121362:A605_RS12720
uniprot id: M1P148
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1121362:A605 RS02550
gene id: 1121362:A605_RS02550
uniprot id: M1P4G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1121362:A605 RS10550
gene id: 1121362:A605_RS10550
uniprot id: M1MZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1121362:A605 RS01885
gene id: 1121362:A605_RS01885
uniprot id: M1P3Z5
names: Similarity
messages: Belongs to the peptidase M1 family.

1121362:A605 RS09120
gene id: 1121362:A605_RS09120
uniprot id: M1NZ53
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS00760
gene id: 1121362:A605_RS00760
uniprot id: M1NUI2
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1121362:A605 RS10115
gene id: 1121362:A605_RS10115
uniprot id: M1NZT2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1121362:A605 RS06470
gene id: 1121362:A605_RS06470
uniprot id: M1NS22
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1121362:A605 RS00275
gene id: 1121362:A605_RS00275
uniprot id: M1NU90
names: Similarity
messages: Belongs to the CsoR family.

1121362:A605 RS12345
gene id: 1121362:A605_RS12345
uniprot id: M1NPW1
names: Similarity
messages: Belongs to the Nth/MutY family.

1121362:A605 RS10680
gene id: 1121362:A605_RS10680
uniprot id: M1P019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1121362:A605 RS01995
gene id: 1121362:A605_RS01995
uniprot id: M1NJ15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1121362:A605 RS04710
gene id: 1121362:A605_RS04710
uniprot id: M1NWS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS11285
gene id: 1121362:A605_RS11285
uniprot id: M1NUQ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1121362:A605 RS10950
gene id: 1121362:A605_RS10950
uniprot id: M1P065
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121362:A605 RS08150
gene id: 1121362:A605_RS08150
uniprot id: M1NT18
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1121362:A605 RS06160
gene id: 1121362:A605_RS06160
uniprot id: M1NXJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1121362:A605 RS10580
gene id: 1121362:A605_RS10580
uniprot id: M1P005
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1121362:A605 RS00675
gene id: 1121362:A605_RS00675
uniprot id: M1NNS8
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1121362:A605 RS09535
gene id: 1121362:A605_RS09535
uniprot id: M1NZE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1121362:A605 RS07810
gene id: 1121362:A605_RS07810
uniprot id: M1NMG4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1121362:A605 RS03835
gene id: 1121362:A605_RS03835
uniprot id: M1NQH8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121362:A605 RS11515
gene id: 1121362:A605_RS11515
uniprot id: M1NPF6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1121362:A605 RS02525
gene id: 1121362:A605_RS02525
uniprot id: M1P4F8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1121362:A605 RS09010
gene id: 1121362:A605_RS09010
uniprot id: M1NN29
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1121362:A605 RS11880
gene id: 1121362:A605_RS11880
uniprot id: M1P0N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS12430
gene id: 1121362:A605_RS12430
uniprot id: M1NVD1
names: Similarity
messages: Belongs to the pantothenate synthetase family.

1121362:A605 RS11905
gene id: 1121362:A605_RS11905
uniprot id: M1P0N7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS12475
gene id: 1121362:A605_RS12475
uniprot id: M1P9W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1121362:A605 RS10565
gene id: 1121362:A605_RS10565
uniprot id: M1NUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121362:A605 RS11815
gene id: 1121362:A605_RS11815
uniprot id: M1N035
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1121362:A605 RS14525
gene id: 1121362:A605_RS14525
uniprot id: M1PB10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1121362:A605 RS07760
gene id: 1121362:A605_RS07760
uniprot id: M1NMF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121362:A605 RS03745
gene id: 1121362:A605_RS03745
uniprot id: M1MVJ8
names: Similarity
messages: Belongs to the thymidylate kinase family.

1121362:A605 RS12025
gene id: 1121362:A605_RS12025
uniprot id: M1P0Q3
names: Similarity
messages: Belongs to the PstS family.

1121362:A605 RS01015
gene id: 1121362:A605_RS01015
uniprot id: M1NUM9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-71 and Arg-74) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1121362:A605 RS09175
gene id: 1121362:A605_RS09175
uniprot id: M1P815
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09600
gene id: 1121362:A605_RS09600
uniprot id: M1NNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1121362:A605 RS13750
gene id: 1121362:A605_RS13750
uniprot id: M1P1L3
names: Similarity
messages: Belongs to the UPF0371 family.

1121362:A605 RS00085
gene id: 1121362:A605_RS00085
uniprot id: M1NI17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1121362:A605 RS15935
gene id: 1121362:A605_RS15935
uniprot id: M1MWF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.

1121362:A605 RS14120
gene id: 1121362:A605_RS14120
uniprot id: M1P1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1121362:A605 RS11790
gene id: 1121362:A605_RS11790
uniprot id: M1N029
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1121362:A605 RS08955
gene id: 1121362:A605_RS08955
uniprot id: M1NTG4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1121362:A605 RS12740
gene id: 1121362:A605_RS12740
uniprot id: M1N0S6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS12305
gene id: 1121362:A605_RS12305
uniprot id: M1P0V8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS14495
gene id: 1121362:A605_RS14495
uniprot id: M1P205
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1121362:A605 RS11890
gene id: 1121362:A605_RS11890
uniprot id: M1NV20
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1121362:A605 RS10830
gene id: 1121362:A605_RS10830
uniprot id: M1P8Z1
names: Similarity
messages: Belongs to the peptidase S33 family.

1121362:A605 RS08030
gene id: 1121362:A605_RS08030
uniprot id: M1NT01
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1121362:A605 RS02530
gene id: 1121362:A605_RS02530
uniprot id: M1NPV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1121362:A605 RS07355
gene id: 1121362:A605_RS07355
uniprot id: M1NM61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1121362:A605 RS04270
gene id: 1121362:A605_RS04270
uniprot id: M1MVT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1121362:A605 RS02455
gene id: 1121362:A605_RS02455
uniprot id: M1NPT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1121362:A605 RS09435
gene id: 1121362:A605_RS09435
uniprot id: M1MYS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1121362:A605 RS09865
gene id: 1121362:A605_RS09865
uniprot id: M1P8G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1121362:A605 RS02625
gene id: 1121362:A605_RS02625
uniprot id: M1NVL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1121362:A605 RS02705
gene id: 1121362:A605_RS02705
uniprot id: M1P4I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1121362:A605 RS04380
gene id: 1121362:A605_RS04380
uniprot id: M1P5D8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1121362:A605 RS04820
gene id: 1121362:A605_RS04820
uniprot id: M1NR19
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09200
gene id: 1121362:A605_RS09200
uniprot id: M1P820
names: Similarity
messages: Belongs to the acylphosphatase family.

1121362:A605 RS09285
gene id: 1121362:A605_RS09285
uniprot id: M1NN93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS00005
gene id: 1121362:A605_RS00005
uniprot id: M1MTK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1121362:A605 RS06205
gene id: 1121362:A605_RS06205
uniprot id: M1MWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1121362:A605 RS09480
gene id: 1121362:A605_RS09480
uniprot id: M1MYT3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1121362:A605 RS10490
gene id: 1121362:A605_RS10490
uniprot id: M1NUB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS01315
gene id: 1121362:A605_RS01315
uniprot id: M1MU75
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121362:A605 RS06955
gene id: 1121362:A605_RS06955
uniprot id: M1NLW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1121362:A605 RS06540
gene id: 1121362:A605_RS06540
uniprot id: M1P6L1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS11045
gene id: 1121362:A605_RS11045
uniprot id: M1MZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1121362:A605 RS05955
gene id: 1121362:A605_RS05955
uniprot id: M1NXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1121362:A605 RS10540
gene id: 1121362:A605_RS10540
uniprot id: M1NUC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1121362:A605 RS13925
gene id: 1121362:A605_RS13925
uniprot id: M1P1P5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121362:A605 RS02635
gene id: 1121362:A605_RS02635
uniprot id: M1NPX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1121362:A605 RS11450
gene id: 1121362:A605_RS11450
uniprot id: M1P9A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1121362:A605 RS09420
gene id: 1121362:A605_RS09420
uniprot id: M1P863
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1121362:A605 RS10150
gene id: 1121362:A605_RS10150
uniprot id: M1P8M3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1121362:A605 RS01685
gene id: 1121362:A605_RS01685
uniprot id: M1NPA5
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS08905
gene id: 1121362:A605_RS08905
uniprot id: M1NTF2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121362:A605 RS08605
gene id: 1121362:A605_RS08605
uniprot id: M1NT94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1121362:A605 RS06825
gene id: 1121362:A605_RS06825
uniprot id: M1NS93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1121362:A605 RS08500
gene id: 1121362:A605_RS08500
uniprot id: M1P7N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1121362:A605 RS12405
gene id: 1121362:A605_RS12405
uniprot id: M1NVC5
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS03155
gene id: 1121362:A605_RS03155
uniprot id: M1P4Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1121362:A605 RS07455
gene id: 1121362:A605_RS07455
uniprot id: M1NM96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1121362:A605 RS10690
gene id: 1121362:A605_RS10690
uniprot id: M1NUE6
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS07770
gene id: 1121362:A605_RS07770
uniprot id: M1NYG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1121362:A605 RS05350
gene id: 1121362:A605_RS05350
uniprot id: M1MWF7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121362:A605 RS12030
gene id: 1121362:A605_RS12030
uniprot id: M1P9L2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121362:A605 RS03165
gene id: 1121362:A605_RS03165
uniprot id: M1NJR2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1121362:A605 RS14450
gene id: 1121362:A605_RS14450
uniprot id: M1PAZ3
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS08140
gene id: 1121362:A605_RS08140
uniprot id: M1NYN2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1121362:A605 RS12485
gene id: 1121362:A605_RS12485
uniprot id: M1NPZ4
names: Similarity
messages: Belongs to the peptidase S13 family.

1121362:A605 RS08200
gene id: 1121362:A605_RS08200
uniprot id: M1NT27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1121362:A605 RS11875
gene id: 1121362:A605_RS11875
uniprot id: M1N045
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1121362:A605 RS09565
gene id: 1121362:A605_RS09565
uniprot id: M1P895
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1121362:A605 RS06730
gene id: 1121362:A605_RS06730
uniprot id: M1MX46
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1121362:A605 RS07435
gene id: 1121362:A605_RS07435
uniprot id: M1MXK6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1121362:A605 RS05330
gene id: 1121362:A605_RS05330
uniprot id: M1NX46
names: Similarity
messages: Belongs to the thymidine kinase family.

1121362:A605 RS11605
gene id: 1121362:A605_RS11605
uniprot id: M1NPH2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1121362:A605 RS09595
gene id: 1121362:A605_RS09595
uniprot id: M1NTU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1121362:A605 RS07585
gene id: 1121362:A605_RS07585
uniprot id: M1NMC7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1121362:A605 RS08770
gene id: 1121362:A605_RS08770
uniprot id: M1NYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1121362:A605 RS12225
gene id: 1121362:A605_RS12225
uniprot id: M1P0U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1121362:A605 RS02560
gene id: 1121362:A605_RS02560
uniprot id: M1NJG4
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1121362:A605 RS10535
gene id: 1121362:A605_RS10535
uniprot id: M1P8T7
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS02710
gene id: 1121362:A605_RS02710
uniprot id: M1NPY4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121362:A605 RS11835
gene id: 1121362:A605_RS11835
uniprot id: M1NPL9
names: Similarity
messages: Belongs to the fructosamine kinase family.

1121362:A605 RS03680
gene id: 1121362:A605_RS03680
uniprot id: M1P4Z8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1121362:A605 RS06215
gene id: 1121362:A605_RS06215
uniprot id: M1P6D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1121362:A605 RS07895
gene id: 1121362:A605_RS07895
uniprot id: M1NYI8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS06445
gene id: 1121362:A605_RS06445
uniprot id: M1NS15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS08715
gene id: 1121362:A605_RS08715
uniprot id: M1MYA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1121362:A605 RS07555
gene id: 1121362:A605_RS07555
uniprot id: M1NMC2
names: Similarity
messages: Belongs to the UPF0098 family.

1121362:A605 RS02675
gene id: 1121362:A605_RS02675
uniprot id: M1NVM2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1121362:A605 RS10500
gene id: 1121362:A605_RS10500
uniprot id: M1MZF2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1121362:A605 RS09145
gene id: 1121362:A605_RS09145
uniprot id: M1NZ59
names: Similarity
messages: Belongs to the P(II) protein family.

1121362:A605 RS07925
gene id: 1121362:A605_RS07925
uniprot id: M1P7F0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS13580
gene id: 1121362:A605_RS13580
uniprot id: M1P1I7
names: Similarity
messages: Belongs to the universal stress protein A family.

1121362:A605 RS02450
gene id: 1121362:A605_RS02450
uniprot id: M1P4E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1121362:A605 RS03235
gene id: 1121362:A605_RS03235
uniprot id: M1NQ72
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS03170
gene id: 1121362:A605_RS03170
uniprot id: M1MV91
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1121362:A605 RS11935
gene id: 1121362:A605_RS11935
uniprot id: M1NPN5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1121362:A605 RS02200
gene id: 1121362:A605_RS02200
uniprot id: M1NVD5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1121362:A605 RS07655
gene id: 1121362:A605_RS07655
uniprot id: M1NSU4
names: Subcellular Location Annotation
messages: Cell membrane

1121362:A605 RS14230
gene id: 1121362:A605_RS14230
uniprot id: M1NWD1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121362:A605 RS05620
gene id: 1121362:A605_RS05620
uniprot id: M1NRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1121362:A605 RS08100
gene id: 1121362:A605_RS08100
uniprot id: M1P7H9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1121362:A605 RS07185
gene id: 1121362:A605_RS07185
uniprot id: M1NM14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1121362:A605 RS02180
gene id: 1121362:A605_RS02180
uniprot id: M1P476
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1121362:A605 RS03905
gene id: 1121362:A605_RS03905
uniprot id: M1P540
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1121362:A605 RS03145
gene id: 1121362:A605_RS03145
uniprot id: M1MV84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1121362:A605 RS05345
gene id: 1121362:A605_RS05345
uniprot id: M1NKZ8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1121362:A605 RS11105
gene id: 1121362:A605_RS11105
uniprot id: M1P938
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1121362:A605 RS06525
gene id: 1121362:A605_RS06525
uniprot id: M1NLL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1121362:A605 RS10840
gene id: 1121362:A605_RS10840
uniprot id: M1NP54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cell inner membrane
messages: Membrane

1121362:A605 RS08415
gene id: 1121362:A605_RS08415
uniprot id: M1MY52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS13685
gene id: 1121362:A605_RS13685
uniprot id: M1NW32
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1121362:A605 RS02195
gene id: 1121362:A605_RS02195
uniprot id: M1MUN1
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1121362:A605 RS13850
gene id: 1121362:A605_RS13850
uniprot id: M1P1N0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1121362:A605 RS02535
gene id: 1121362:A605_RS02535
uniprot id: M1NJF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1121362:A605 RS13090
gene id: 1121362:A605_RS13090
uniprot id: M1NQC5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1121362:A605 RS01680
gene id: 1121362:A605_RS01680
uniprot id: M1P3U4
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

1121362:A605 RS07420
gene id: 1121362:A605_RS07420
uniprot id: M1P757
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1121362:A605 RS11230
gene id: 1121362:A605_RS11230
uniprot id: M1P960
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS06095
gene id: 1121362:A605_RS06095
uniprot id: M1NRT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121362:A605 RS09845
gene id: 1121362:A605_RS09845
uniprot id: M1NTZ8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1121362:A605 RS09235
gene id: 1121362:A605_RS09235
uniprot id: M1NN81
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1121362:A605 RS03255
gene id: 1121362:A605_RS03255
uniprot id: M1P4S5
names: Similarity
messages: Belongs to the peptidase C40 family.

1121362:A605 RS09165
gene id: 1121362:A605_RS09165
uniprot id: M1MYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS06925
gene id: 1121362:A605_RS06925
uniprot id: M1NSB8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1121362:A605 RS02925
gene id: 1121362:A605_RS02925
uniprot id: M1NVS2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121362:A605 RS09805
gene id: 1121362:A605_RS09805
uniprot id: M1MZ16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1121362:A605 RS01755
gene id: 1121362:A605_RS01755
uniprot id: M1P3W1
names: Subcellular Location Annotation
messages: Cytoplasm

1121362:A605 RS14155
gene id: 1121362:A605_RS14155
uniprot id: M1NWB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1121362:A605 RS03990
gene id: 1121362:A605_RS03990
uniprot id: M1NQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1121362:A605 RS13470
gene id: 1121362:A605_RS13470
uniprot id: M1NQJ3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

1121362:A605 RS03355
gene id: 1121362:A605_RS03355
uniprot id: M1NW02
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121362:A605 RS05285
gene id: 1121362:A605_RS05285
uniprot id: M1P5Z0
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS13395
gene id: 1121362:A605_RS13395
uniprot id: M1NQH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1121362:A605 RS12900
gene id: 1121362:A605_RS12900
uniprot id: M1PA50
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1121362:A605 RS09855
gene id: 1121362:A605_RS09855
uniprot id: M1MZ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1121362:A605 RS05505
gene id: 1121362:A605_RS05505
uniprot id: M1MWI2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1121362:A605 RS02225
gene id: 1121362:A605_RS02225
uniprot id: M1NVE1
names: Similarity
messages: Belongs to the asparaginase 1 family.

1121362:A605 RS06295
gene id: 1121362:A605_RS06295
uniprot id: M1NRY1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1121362:A605 RS00345
gene id: 1121362:A605_RS00345
uniprot id: M1MTR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS03225
gene id: 1121362:A605_RS03225
uniprot id: M1NVX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS07920
gene id: 1121362:A605_RS07920
uniprot id: M1NYJ3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1121362:A605 RS00200
gene id: 1121362:A605_RS00200
uniprot id: M1NU79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1121362:A605 RS02295
gene id: 1121362:A605_RS02295
uniprot id: M1MUR2
names: Similarity
messages: Belongs to the peptidase S51 family.

1121362:A605 RS14640
gene id: 1121362:A605_RS14640
uniprot id: M1NR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121362:A605 RS09675
gene id: 1121362:A605_RS09675
uniprot id: M1NNI4
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

1121362:A605 RS07685
gene id: 1121362:A605_RS07685
uniprot id: M1NME4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1121362:A605 RS06210
gene id: 1121362:A605_RS06210
uniprot id: M1NXK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1121362:A605 RS00335
gene id: 1121362:A605_RS00335
uniprot id: M1NNM4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1121362:A605 RS12110
gene id: 1121362:A605_RS12110
uniprot id: M1NV58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1121362:A605 RS03455
gene id: 1121362:A605_RS03455
uniprot id: M1NW20
names: Similarity
messages: Belongs to the AccD/PCCB family.

1121362:A605 RS07775
gene id: 1121362:A605_RS07775
uniprot id: M1P7C7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121362:A605 RS08835
gene id: 1121362:A605_RS08835
uniprot id: M1NMZ1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1121362:A605 RS04305
gene id: 1121362:A605_RS04305
uniprot id: M1P5C1
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS02875
gene id: 1121362:A605_RS02875
uniprot id: M1NVR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1121362:A605 RS00980
gene id: 1121362:A605_RS00980
uniprot id: M1NIG8
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS06335
gene id: 1121362:A605_RS06335
uniprot id: M1NXN1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1121362:A605 RS03980
gene id: 1121362:A605_RS03980
uniprot id: M1NWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1121362:A605 RS07795
gene id: 1121362:A605_RS07795
uniprot id: M1NYH1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS08550
gene id: 1121362:A605_RS08550
uniprot id: M1P7P3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121362:A605 RS09325
gene id: 1121362:A605_RS09325
uniprot id: M1P845
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1121362:A605 RS02035
gene id: 1121362:A605_RS02035
uniprot id: M1P438
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1121362:A605 RS05065
gene id: 1121362:A605_RS05065
uniprot id: M1NR81
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS14240
gene id: 1121362:A605_RS14240
uniprot id: M1N1K6
names: Similarity
messages: Belongs to the thioredoxin family.

1121362:A605 RS03370
gene id: 1121362:A605_RS03370
uniprot id: M1NJV0
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS13895
gene id: 1121362:A605_RS13895
uniprot id: M1N1C5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1121362:A605 RS01365
gene id: 1121362:A605_RS01365
uniprot id: M1NIN2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121362:A605 RS10805
gene id: 1121362:A605_RS10805
uniprot id: M1P8Y5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1121362:A605 RS02495
gene id: 1121362:A605_RS02495
uniprot id: M1NVJ3
names: Similarity
messages: Belongs to the asp23 family.

1121362:A605 RS09505
gene id: 1121362:A605_RS09505
uniprot id: M1MYT8
names: Similarity
messages: Belongs to the asparaginase 1 family.

1121362:A605 RS07975
gene id: 1121362:A605_RS07975
uniprot id: M1P7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1121362:A605 RS06845
gene id: 1121362:A605_RS06845
uniprot id: M1P6S0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1121362:A605 RS00990
gene id: 1121362:A605_RS00990
uniprot id: M1NUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS06100
gene id: 1121362:A605_RS06100
uniprot id: M1NLC6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1121362:A605 RS10300
gene id: 1121362:A605_RS10300
uniprot id: M1P8P9
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS07440
gene id: 1121362:A605_RS07440
uniprot id: M1NYA3
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1121362:A605 RS00045
gene id: 1121362:A605_RS00045
uniprot id: M1NNI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1121362:A605 RS00775
gene id: 1121362:A605_RS00775
uniprot id: M1NID3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1121362:A605 RS13295
gene id: 1121362:A605_RS13295
uniprot id: M1NQG1
names: Similarity
messages: Belongs to the AccD/PCCB family.

1121362:A605 RS09975
gene id: 1121362:A605_RS09975
uniprot id: M1NU31
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1121362:A605 RS06850
gene id: 1121362:A605_RS06850
uniprot id: M1NS98
names: Similarity
messages: Belongs to the universal stress protein A family.

1121362:A605 RS08215
gene id: 1121362:A605_RS08215
uniprot id: M1NYP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1121362:A605 RS03005
gene id: 1121362:A605_RS03005
uniprot id: M1P4N3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1121362:A605 RS04220
gene id: 1121362:A605_RS04220
uniprot id: M1MVS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS12605
gene id: 1121362:A605_RS12605
uniprot id: M1NVI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS13650
gene id: 1121362:A605_RS13650
uniprot id: M1PAH2
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS10615
gene id: 1121362:A605_RS10615
uniprot id: M1NUD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1121362:A605 RS05025
gene id: 1121362:A605_RS05025
uniprot id: M1NWZ4
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS00260
gene id: 1121362:A605_RS00260
uniprot id: M1NNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS14260
gene id: 1121362:A605_RS14260
uniprot id: M1NR03
names: Similarity
messages: Belongs to the ParB family.

1121362:A605 RS04595
gene id: 1121362:A605_RS04595
uniprot id: M1NQX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1121362:A605 RS06315
gene id: 1121362:A605_RS06315
uniprot id: M1P6G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1121362:A605 RS07645
gene id: 1121362:A605_RS07645
uniprot id: M1NYE7
names: Similarity
messages: Belongs to the UPF0237 family.

1121362:A605 RS06345
gene id: 1121362:A605_RS06345
uniprot id: M1NRZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1121362:A605 RS03110
gene id: 1121362:A605_RS03110
uniprot id: M1NQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121362:A605 RS12290
gene id: 1121362:A605_RS12290
uniprot id: M1NV95
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1121362:A605 RS06390
gene id: 1121362:A605_RS06390
uniprot id: M1P6I1
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

1121362:A605 RS11115
gene id: 1121362:A605_RS11115
uniprot id: M1NP91
names: Similarity
messages: Belongs to the pirin family.

1121362:A605 RS14535
gene id: 1121362:A605_RS14535
uniprot id: M1NR72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS11925
gene id: 1121362:A605_RS11925
uniprot id: M1P9J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS06225
gene id: 1121362:A605_RS06225
uniprot id: M1NLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1121362:A605 RS07970
gene id: 1121362:A605_RS07970
uniprot id: M1NYK3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1121362:A605 RS08910
gene id: 1121362:A605_RS08910
uniprot id: M1NN05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1121362:A605 RS01980
gene id: 1121362:A605_RS01980
uniprot id: M1NV79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1121362:A605 RS01300
gene id: 1121362:A605_RS01300
uniprot id: M1P3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1121362:A605 RS09335
gene id: 1121362:A605_RS09335
uniprot id: M1NNA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1121362:A605 RS00650
gene id: 1121362:A605_RS00650
uniprot id: M1NNS4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1121362:A605 RS06690
gene id: 1121362:A605_RS06690
uniprot id: M1P6N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1121362:A605 RS07935
gene id: 1121362:A605_RS07935
uniprot id: M1NMI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1121362:A605 RS07000
gene id: 1121362:A605_RS07000
uniprot id: M1NLW6
names: Similarity
messages: Belongs to the TlyA family.

1121362:A605 RS05935
gene id: 1121362:A605_RS05935
uniprot id: M1P6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1121362:A605 RS07035
gene id: 1121362:A605_RS07035
uniprot id: M1NY16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1121362:A605 RS04395
gene id: 1121362:A605_RS04395
uniprot id: M1MVV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1121362:A605 RS08755
gene id: 1121362:A605_RS08755
uniprot id: M1NTC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1121362:A605 RS08485
gene id: 1121362:A605_RS08485
uniprot id: M1NMS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1121362:A605 RS05745
gene id: 1121362:A605_RS05745
uniprot id: M1NL68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1121362:A605 RS08205
gene id: 1121362:A605_RS08205
uniprot id: M1NMN6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1121362:A605 RS13270
gene id: 1121362:A605_RS13270
uniprot id: M1NQF7
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS02215
gene id: 1121362:A605_RS02215
uniprot id: M1NJ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS14415
gene id: 1121362:A605_RS14415
uniprot id: M1PAY8
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS05715
gene id: 1121362:A605_RS05715
uniprot id: M1NRL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1121362:A605 RS12080
gene id: 1121362:A605_RS12080
uniprot id: M1P9M2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1121362:A605 RS02395
gene id: 1121362:A605_RS02395
uniprot id: M1NVH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1121362:A605 RS12940
gene id: 1121362:A605_RS12940
uniprot id: M1N0V6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121362:A605 RS03480
gene id: 1121362:A605_RS03480
uniprot id: M1NW25
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1121362:A605 RS06545
gene id: 1121362:A605_RS06545
uniprot id: M1NS38
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS04845
gene id: 1121362:A605_RS04845
uniprot id: M1NR23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS08125
gene id: 1121362:A605_RS08125
uniprot id: M1NT16
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1121362:A605 RS12480
gene id: 1121362:A605_RS12480
uniprot id: M1NVE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1121362:A605 RS10555
gene id: 1121362:A605_RS10555
uniprot id: M1P001
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1121362:A605 RS12145
gene id: 1121362:A605_RS12145
uniprot id: M1N091
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1121362:A605 RS06320
gene id: 1121362:A605_RS06320
uniprot id: M1NRY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1121362:A605 RS02045
gene id: 1121362:A605_RS02045
uniprot id: M1MUJ6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1121362:A605 RS01400
gene id: 1121362:A605_RS01400
uniprot id: M1NIN5
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS00520
gene id: 1121362:A605_RS00520
uniprot id: M1P361
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1121362:A605 RS13515
gene id: 1121362:A605_RS13515
uniprot id: M1NW04
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1121362:A605 RS02730
gene id: 1121362:A605_RS02730
uniprot id: M1P4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1121362:A605 RS12525
gene id: 1121362:A605_RS12525
uniprot id: M1P9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1121362:A605 RS06750
gene id: 1121362:A605_RS06750
uniprot id: M1NLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS11345
gene id: 1121362:A605_RS11345
uniprot id: M1P0D5
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1121362:A605 RS12105
gene id: 1121362:A605_RS12105
uniprot id: M1P9M7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1121362:A605 RS06935
gene id: 1121362:A605_RS06935
uniprot id: M1MX88
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1121362:A605 RS03040
gene id: 1121362:A605_RS03040
uniprot id: M1NJP2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1121362:A605 RS05400
gene id: 1121362:A605_RS05400
uniprot id: M1MWG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1121362:A605 RS05385
gene id: 1121362:A605_RS05385
uniprot id: M1P608
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1121362:A605 RS03440
gene id: 1121362:A605_RS03440
uniprot id: M1NQA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1121362:A605 RS09345
gene id: 1121362:A605_RS09345
uniprot id: M1NZA2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1121362:A605 RS02340
gene id: 1121362:A605_RS02340
uniprot id: M1NJC6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1121362:A605 RS08705
gene id: 1121362:A605_RS08705
uniprot id: M1NTB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1121362:A605 RS09265
gene id: 1121362:A605_RS09265
uniprot id: M1MYN1
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1121362:A605 RS03000
gene id: 1121362:A605_RS03000
uniprot id: M1NVT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1121362:A605 RS12205
gene id: 1121362:A605_RS12205
uniprot id: M1P9P7
names: Similarity
messages: Belongs to the TPP enzyme family.

1121362:A605 RS00230
gene id: 1121362:A605_RS00230
uniprot id: M1NNK8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1121362:A605 RS09860
gene id: 1121362:A605_RS09860
uniprot id: M1NZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1121362:A605 RS13190
gene id: 1121362:A605_RS13190
uniprot id: M1NVU3
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS01260
gene id: 1121362:A605_RS01260
uniprot id: M1NIL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS10455
gene id: 1121362:A605_RS10455
uniprot id: M1NZY4
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1121362:A605 RS13690
gene id: 1121362:A605_RS13690
uniprot id: M1NQN4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS11820
gene id: 1121362:A605_RS11820
uniprot id: M1P0M1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1121362:A605 RS03335
gene id: 1121362:A605_RS03335
uniprot id: M1P4T6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121362:A605 RS02285
gene id: 1121362:A605_RS02285
uniprot id: M1NPN8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS01500
gene id: 1121362:A605_RS01500
uniprot id: M1NUX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1121362:A605 RS12020
gene id: 1121362:A605_RS12020
uniprot id: M1N067
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1121362:A605 RS09170
gene id: 1121362:A605_RS09170
uniprot id: M1NZ65
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09005
gene id: 1121362:A605_RS09005
uniprot id: M1NTH3
names: Similarity
messages: Belongs to the DprA/Smf family.

1121362:A605 RS06915
gene id: 1121362:A605_RS06915
uniprot id: M1NXZ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121362:A605 RS07830
gene id: 1121362:A605_RS07830
uniprot id: M1NSX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1121362:A605 RS08320
gene id: 1121362:A605_RS08320
uniprot id: M1MY31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

1121362:A605 RS13565
gene id: 1121362:A605_RS13565
uniprot id: M1NW13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1121362:A605 RS02575
gene id: 1121362:A605_RS02575
uniprot id: M1P4G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1121362:A605 RS06040
gene id: 1121362:A605_RS06040
uniprot id: M1NRR9
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1121362:A605 RS04640
gene id: 1121362:A605_RS04640
uniprot id: M1P5J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1121362:A605 RS02415
gene id: 1121362:A605_RS02415
uniprot id: M1MUU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1121362:A605 RS08430
gene id: 1121362:A605_RS08430
uniprot id: M1NT60
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1121362:A605 RS06920
gene id: 1121362:A605_RS06920
uniprot id: M1P6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1121362:A605 RS02075
gene id: 1121362:A605_RS02075
uniprot id: M1NVA4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1121362:A605 RS13835
gene id: 1121362:A605_RS13835
uniprot id: M1NW57
names: Similarity
messages: Belongs to the FPG family.

1121362:A605 RS08020
gene id: 1121362:A605_RS08020
uniprot id: M1NYL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1121362:A605 RS07500
gene id: 1121362:A605_RS07500
uniprot id: M1NSR8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1121362:A605 RS00915
gene id: 1121362:A605_RS00915
uniprot id: M1NUK9
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS14280
gene id: 1121362:A605_RS14280
uniprot id: M1NR08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1121362:A605 RS08630
gene id: 1121362:A605_RS08630
uniprot id: M1NT99
names: Similarity
messages: Belongs to the PspA/IM30 family.

1121362:A605 RS02995
gene id: 1121362:A605_RS02995
uniprot id: M1MV58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1121362:A605 RS13820
gene id: 1121362:A605_RS13820
uniprot id: M1N1B0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1121362:A605 RS06930
gene id: 1121362:A605_RS06930
uniprot id: M1NLV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1121362:A605 RS02510
gene id: 1121362:A605_RS02510
uniprot id: M1NJF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1121362:A605 RS08645
gene id: 1121362:A605_RS08645
uniprot id: M1NYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1121362:A605 RS09185
gene id: 1121362:A605_RS09185
uniprot id: M1NN70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1121362:A605 RS04565
gene id: 1121362:A605_RS04565
uniprot id: M1P5I0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1121362:A605 RS00090
gene id: 1121362:A605_RS00090
uniprot id: M1MTM1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1121362:A605 RS10825
gene id: 1121362:A605_RS10825
uniprot id: M1P042
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS07610
gene id: 1121362:A605_RS07610
uniprot id: M1NMD1
names: Similarity
messages: Belongs to the peptidase C40 family.

1121362:A605 RS03675
gene id: 1121362:A605_RS03675
uniprot id: M1NW62
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1121362:A605 RS09115
gene id: 1121362:A605_RS09115
uniprot id: M1MYJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1121362:A605 RS05110
gene id: 1121362:A605_RS05110
uniprot id: M1P5W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1121362:A605 RS12665
gene id: 1121362:A605_RS12665
uniprot id: M1N0R3
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS14070
gene id: 1121362:A605_RS14070
uniprot id: M1N1G7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

1121362:A605 RS04900
gene id: 1121362:A605_RS04900
uniprot id: M1NR44
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1121362:A605 RS03140
gene id: 1121362:A605_RS03140
uniprot id: M1NJQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS05090
gene id: 1121362:A605_RS05090
uniprot id: M1NR86
names: Similarity
messages: Belongs to the FBPase class 2 family.

1121362:A605 RS09260
gene id: 1121362:A605_RS09260
uniprot id: M1NN86
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1121362:A605 RS13200
gene id: 1121362:A605_RS13200
uniprot id: M1N0Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1121362:A605 RS04680
gene id: 1121362:A605_RS04680
uniprot id: M1MW29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1121362:A605 RS03845
gene id: 1121362:A605_RS03845
uniprot id: M1MVL5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1121362:A605 RS02300
gene id: 1121362:A605_RS02300
uniprot id: M1NVG3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1121362:A605 RS12600
gene id: 1121362:A605_RS12600
uniprot id: M1PA04
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS05115
gene id: 1121362:A605_RS05115
uniprot id: M1NR91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1121362:A605 RS12610
gene id: 1121362:A605_RS12610
uniprot id: M1NQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS13240
gene id: 1121362:A605_RS13240
uniprot id: M1NVV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1121362:A605 RS06440
gene id: 1121362:A605_RS06440
uniprot id: M1P6J3
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS13825
gene id: 1121362:A605_RS13825
uniprot id: M1P1M8
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09195
gene id: 1121362:A605_RS09195
uniprot id: M1NZ70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1121362:A605 RS03025
gene id: 1121362:A605_RS03025
uniprot id: M1NVU0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1121362:A605 RS08025
gene id: 1121362:A605_RS08025
uniprot id: M1P7G7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1121362:A605 RS08930
gene id: 1121362:A605_RS08930
uniprot id: M1NTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1121362:A605 RS10600
gene id: 1121362:A605_RS10600
uniprot id: M1MZG7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1121362:A605 RS13215
gene id: 1121362:A605_RS13215
uniprot id: M1NVU8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS02795
gene id: 1121362:A605_RS02795
uniprot id: M1MV22
names: Similarity
messages: Belongs to the CFA/CMAS family.

1121362:A605 RS07105
gene id: 1121362:A605_RS07105
uniprot id: M1MXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1121362:A605 RS00810
gene id: 1121362:A605_RS00810
uniprot id: M1NUJ1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1121362:A605 RS01585
gene id: 1121362:A605_RS01585
uniprot id: M1NP84
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1121362:A605 RS05120
gene id: 1121362:A605_RS05120
uniprot id: M1NKW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1121362:A605 RS04020
gene id: 1121362:A605_RS04020
uniprot id: M1NK65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1121362:A605 RS10025
gene id: 1121362:A605_RS10025
uniprot id: M1NU49
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS14030
gene id: 1121362:A605_RS14030
uniprot id: M1PAP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121362:A605 RS04445
gene id: 1121362:A605_RS04445
uniprot id: M1MVX2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121362:A605 RS06875
gene id: 1121362:A605_RS06875
uniprot id: M1NSA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1121362:A605 RS04560
gene id: 1121362:A605_RS04560
uniprot id: M1NWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1121362:A605 RS07840
gene id: 1121362:A605_RS07840
uniprot id: M1MXT8
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1121362:A605 RS13020
gene id: 1121362:A605_RS13020
uniprot id: M1N0W5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1121362:A605 RS07800
gene id: 1121362:A605_RS07800
uniprot id: M1P7D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1121362:A605 RS02115
gene id: 1121362:A605_RS02115
uniprot id: M1NJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1121362:A605 RS01430
gene id: 1121362:A605_RS01430
uniprot id: M1NIN9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1121362:A605 RS13370
gene id: 1121362:A605_RS13370
uniprot id: M1NQH3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1121362:A605 RS05005
gene id: 1121362:A605_RS05005
uniprot id: M1P5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1121362:A605 RS13380
gene id: 1121362:A605_RS13380
uniprot id: M1P1F6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS02865
gene id: 1121362:A605_RS02865
uniprot id: M1NJL3
names: Similarity
messages: Belongs to the WXG100 family.

1121362:A605 RS12460
gene id: 1121362:A605_RS12460
uniprot id: M1NPY9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1121362:A605 RS15980
gene id: 1121362:A605_RS15980
uniprot id: M1P9K7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1121362:A605 RS07735
gene id: 1121362:A605_RS07735
uniprot id: M1NMF3
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1121362:A605 RS05780
gene id: 1121362:A605_RS05780
uniprot id: M1NXD1
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS10425
gene id: 1121362:A605_RS10425
uniprot id: M1MZE1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1121362:A605 RS14270
gene id: 1121362:A605_RS14270
uniprot id: M1P1W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1121362:A605 RS07780
gene id: 1121362:A605_RS07780
uniprot id: M1NSW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1121362:A605 RS13120
gene id: 1121362:A605_RS13120
uniprot id: M1NQD0
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1121362:A605 RS00025
gene id: 1121362:A605_RS00025
uniprot id: M1NI08
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1121362:A605 RS08425
gene id: 1121362:A605_RS08425
uniprot id: M1P7M7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS11710
gene id: 1121362:A605_RS11710
uniprot id: M1NPJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1121362:A605 RS13185
gene id: 1121362:A605_RS13185
uniprot id: M1PA97
names: Subcellular Location Annotation
messages: Cytoplasm

1121362:A605 RS09835
gene id: 1121362:A605_RS09835
uniprot id: M1NZL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1121362:A605 RS04650
gene id: 1121362:A605_RS04650
uniprot id: M1NKK1
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS00765
gene id: 1121362:A605_RS00765
uniprot id: M1P3A7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121362:A605 RS00510
gene id: 1121362:A605_RS00510
uniprot id: M1MTU8
names: Similarity
messages: Belongs to the heme oxygenase family.

1121362:A605 RS13670
gene id: 1121362:A605_RS13670
uniprot id: M1N175
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS12300
gene id: 1121362:A605_RS12300
uniprot id: M1N0C6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS07730
gene id: 1121362:A605_RS07730
uniprot id: M1NSV5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1121362:A605 RS02645
gene id: 1121362:A605_RS02645
uniprot id: M1MUZ4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1121362:A605 RS08685
gene id: 1121362:A605_RS08685
uniprot id: M1NMW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1121362:A605 RS02715
gene id: 1121362:A605_RS02715
uniprot id: M1NJI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1121362:A605 RS14060
gene id: 1121362:A605_RS14060
uniprot id: M1NW97
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1121362:A605 RS05850
gene id: 1121362:A605_RS05850
uniprot id: M1MWP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1121362:A605 RS09795
gene id: 1121362:A605_RS09795
uniprot id: M1NTY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1121362:A605 RS06340
gene id: 1121362:A605_RS06340
uniprot id: M1P6G8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1121362:A605 RS07525
gene id: 1121362:A605_RS07525
uniprot id: M1NSS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1121362:A605 RS05390
gene id: 1121362:A605_RS05390
uniprot id: M1NRE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1121362:A605 RS02570
gene id: 1121362:A605_RS02570
uniprot id: M1NVK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1121362:A605 RS00375
gene id: 1121362:A605_RS00375
uniprot id: M1P335
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1121362:A605 RS03230
gene id: 1121362:A605_RS03230
uniprot id: M1P4S0
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS07865
gene id: 1121362:A605_RS07865
uniprot id: M1MXU3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1121362:A605 RS08885
gene id: 1121362:A605_RS08885
uniprot id: M1NN00
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1121362:A605 RS11830
gene id: 1121362:A605_RS11830
uniprot id: M1NV11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1121362:A605 RS13930
gene id: 1121362:A605_RS13930
uniprot id: M1PAM8
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09520
gene id: 1121362:A605_RS09520
uniprot id: M1NTS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1121362:A605 RS12135
gene id: 1121362:A605_RS12135
uniprot id: M1NV63
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS11465
gene id: 1121362:A605_RS11465
uniprot id: M1MZW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1121362:A605 RS06125
gene id: 1121362:A605_RS06125
uniprot id: M1NLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1121362:A605 RS03350
gene id: 1121362:A605_RS03350
uniprot id: M1MVC6
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1121362:A605 RS08875
gene id: 1121362:A605_RS08875
uniprot id: M1P7V5
names: Similarity
messages: Belongs to the MQO family.

1121362:A605 RS13525
gene id: 1121362:A605_RS13525
uniprot id: M1N152
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121362:A605 RS13110
gene id: 1121362:A605_RS13110
uniprot id: M1PA84
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS08340
gene id: 1121362:A605_RS08340
uniprot id: M1NMQ2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1121362:A605 RS08935
gene id: 1121362:A605_RS08935
uniprot id: M1NN11
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS06245
gene id: 1121362:A605_RS06245
uniprot id: M1NRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1121362:A605 RS01085
gene id: 1121362:A605_RS01085
uniprot id: M1NII5
names: Similarity
messages: Belongs to the UPF0145 family.

1121362:A605 RS09720
gene id: 1121362:A605_RS09720
uniprot id: M1NTX4
names: Similarity
messages: Belongs to the peptidase C40 family.

1121362:A605 RS11065
gene id: 1121362:A605_RS11065
uniprot id: M1NP83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1121362:A605 RS02060
gene id: 1121362:A605_RS02060
uniprot id: M1NPI4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1121362:A605 RS03970
gene id: 1121362:A605_RS03970
uniprot id: M1NK58
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1121362:A605 RS02515
gene id: 1121362:A605_RS02515
uniprot id: M1MUW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1121362:A605 RS13000
gene id: 1121362:A605_RS13000
uniprot id: M1P196
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1121362:A605 RS11455
gene id: 1121362:A605_RS11455
uniprot id: M1NUT7
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1121362:A605 RS10605
gene id: 1121362:A605_RS10605
uniprot id: M1P007
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1121362:A605 RS06940
gene id: 1121362:A605_RS06940
uniprot id: M1NY02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1121362:A605 RS00635
gene id: 1121362:A605_RS00635
uniprot id: M1MTW8
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1121362:A605 RS04790
gene id: 1121362:A605_RS04790
uniprot id: M1P5N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1121362:A605 RS07995
gene id: 1121362:A605_RS07995
uniprot id: M1NYK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1121362:A605 RS03540
gene id: 1121362:A605_RS03540
uniprot id: M1NJY2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1121362:A605 RS03240
gene id: 1121362:A605_RS03240
uniprot id: M1NJS7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1121362:A605 RS04490
gene id: 1121362:A605_RS04490
uniprot id: M1NQV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1121362:A605 RS12765
gene id: 1121362:A605_RS12765
uniprot id: M1N0T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1121362:A605 RS02755
gene id: 1121362:A605_RS02755
uniprot id: M1P4J5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1121362:A605 RS08115
gene id: 1121362:A605_RS08115
uniprot id: M1MXZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS13195
gene id: 1121362:A605_RS13195
uniprot id: M1NQE4
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS07825
gene id: 1121362:A605_RS07825
uniprot id: M1P7D6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1121362:A605 RS07100
gene id: 1121362:A605_RS07100
uniprot id: M1NLZ4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1121362:A605 RS11620
gene id: 1121362:A605_RS11620
uniprot id: M1P9D7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1121362:A605 RS03030
gene id: 1121362:A605_RS03030
uniprot id: M1P4N6
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1121362:A605 RS13015
gene id: 1121362:A605_RS13015
uniprot id: M1NQB2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1121362:A605 RS07620
gene id: 1121362:A605_RS07620
uniprot id: M1NYE2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1121362:A605 RS03775
gene id: 1121362:A605_RS03775
uniprot id: M1NW85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1121362:A605 RS09300
gene id: 1121362:A605_RS09300
uniprot id: M1P840
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS06190
gene id: 1121362:A605_RS06190
uniprot id: M1P6D4
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS02945
gene id: 1121362:A605_RS02945
uniprot id: M1MV49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1121362:A605 RS03955
gene id: 1121362:A605_RS03955
uniprot id: M1NWC1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1121362:A605 RS12245
gene id: 1121362:A605_RS12245
uniprot id: M1NPT7
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1121362:A605 RS05465
gene id: 1121362:A605_RS05465
uniprot id: M1P619
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1121362:A605 RS01155
gene id: 1121362:A605_RS01155
uniprot id: M1NP15
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1121362:A605 RS14145
gene id: 1121362:A605_RS14145
uniprot id: M1P1T8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS03560
gene id: 1121362:A605_RS03560
uniprot id: M1NQD1
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS12670
gene id: 1121362:A605_RS12670
uniprot id: M1P143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1121362:A605 RS06945
gene id: 1121362:A605_RS06945
uniprot id: M1P6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1121362:A605 RS02325
gene id: 1121362:A605_RS02325
uniprot id: M1NVG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1121362:A605 RS04975
gene id: 1121362:A605_RS04975
uniprot id: M1NWY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1121362:A605 RS04070
gene id: 1121362:A605_RS04070
uniprot id: M1NWE3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1121362:A605 RS00010
gene id: 1121362:A605_RS00010
uniprot id: M1NU52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1121362:A605 RS12295
gene id: 1121362:A605_RS12295
uniprot id: M1NPV0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1121362:A605 RS07885
gene id: 1121362:A605_RS07885
uniprot id: M1NMH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS09160
gene id: 1121362:A605_RS09160
uniprot id: M1NN65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS10750
gene id: 1121362:A605_RS10750
uniprot id: M1MZJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121362:A605 RS08505
gene id: 1121362:A605_RS08505
uniprot id: M1NT76
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1121362:A605 RS08785
gene id: 1121362:A605_RS08785
uniprot id: M1NMY2
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS13745
gene id: 1121362:A605_RS13745
uniprot id: M1N193
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1121362:A605 RS04105
gene id: 1121362:A605_RS04105
uniprot id: M1NQM7
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1121362:A605 RS06895
gene id: 1121362:A605_RS06895
uniprot id: M1P6T4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1121362:A605 RS04025
gene id: 1121362:A605_RS04025
uniprot id: M1MVP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1121362:A605 RS02390
gene id: 1121362:A605_RS02390
uniprot id: M1MUU0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1121362:A605 RS01800
gene id: 1121362:A605_RS01800
uniprot id: M1NV43
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS07365
gene id: 1121362:A605_RS07365
uniprot id: M1NY78
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1121362:A605 RS10820
gene id: 1121362:A605_RS10820
uniprot id: M1MZK2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1121362:A605 RS02810
gene id: 1121362:A605_RS02810
uniprot id: M1NQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

1121362:A605 RS10670
gene id: 1121362:A605_RS10670
uniprot id: M1NP27
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1121362:A605 RS05830
gene id: 1121362:A605_RS05830
uniprot id: M1NXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1121362:A605 RS06855
gene id: 1121362:A605_RS06855
uniprot id: M1NLT2
names: Similarity
messages: Belongs to the universal stress protein A family.

1121362:A605 RS01910
gene id: 1121362:A605_RS01910
uniprot id: M1P402
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1121362:A605 RS09055
gene id: 1121362:A605_RS09055
uniprot id: M1NTI2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1121362:A605 RS00645
gene id: 1121362:A605_RS00645
uniprot id: M1P384
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1121362:A605 RS09790
gene id: 1121362:A605_RS09790
uniprot id: M1P8E4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1121362:A605 RS00735
gene id: 1121362:A605_RS00735
uniprot id: M1MTY4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1121362:A605 RS11085
gene id: 1121362:A605_RS11085
uniprot id: M1NUL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1121362:A605 RS05130
gene id: 1121362:A605_RS05130
uniprot id: M1NX11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1121362:A605 RS12645
gene id: 1121362:A605_RS12645
uniprot id: M1P139
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1121362:A605 RS03365
gene id: 1121362:A605_RS03365
uniprot id: M1NQ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1121362:A605 RS07545
gene id: 1121362:A605_RS07545
uniprot id: M1P793
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1121362:A605 RS07125
gene id: 1121362:A605_RS07125
uniprot id: M1NM00
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS04165
gene id: 1121362:A605_RS04165
uniprot id: M1MVR5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1121362:A605 RS06510
gene id: 1121362:A605_RS06510
uniprot id: M1NXR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1121362:A605 RS11245
gene id: 1121362:A605_RS11245
uniprot id: M1MZT1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1121362:A605 RS09240
gene id: 1121362:A605_RS09240
uniprot id: M1MYM5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1121362:A605 RS03825
gene id: 1121362:A605_RS03825
uniprot id: M1NW94
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1121362:A605 RS13675
gene id: 1121362:A605_RS13675
uniprot id: M1P1J9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1121362:A605 RS06515
gene id: 1121362:A605_RS06515
uniprot id: M1P6K6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS02935
gene id: 1121362:A605_RS02935
uniprot id: M1NQ22
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1121362:A605 RS07890
gene id: 1121362:A605_RS07890
uniprot id: M1MXU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS08070
gene id: 1121362:A605_RS08070
uniprot id: M1NYM0
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS08675
gene id: 1121362:A605_RS08675
uniprot id: M1P7R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1121362:A605 RS06200
gene id: 1121362:A605_RS06200
uniprot id: M1NLE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1121362:A605 RS03725
gene id: 1121362:A605_RS03725
uniprot id: M1NW73
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1121362:A605 RS07395
gene id: 1121362:A605_RS07395
uniprot id: M1P751
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121362:A605 RS03265
gene id: 1121362:A605_RS03265
uniprot id: M1NJT3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1121362:A605 RS04990
gene id: 1121362:A605_RS04990
uniprot id: M1NKU0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS11025
gene id: 1121362:A605_RS11025
uniprot id: M1P078
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1121362:A605 RS01570
gene id: 1121362:A605_RS01570
uniprot id: M1MUB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS09870
gene id: 1121362:A605_RS09870
uniprot id: M1NU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS09780
gene id: 1121362:A605_RS09780
uniprot id: M1MZ09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1121362:A605 RS01035
gene id: 1121362:A605_RS01035
uniprot id: M1NIH5
names: Similarity
messages: Belongs to the YciI family.

1121362:A605 RS03300
gene id: 1121362:A605_RS03300
uniprot id: M1NVZ2
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1121362:A605 RS03375
gene id: 1121362:A605_RS03375
uniprot id: M1MVD0
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

1121362:A605 RS13900
gene id: 1121362:A605_RS13900
uniprot id: M1P1P1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1121362:A605 RS05645
gene id: 1121362:A605_RS05645
uniprot id: M1NRJ8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1121362:A605 RS03660
gene id: 1121362:A605_RS03660
uniprot id: M1NQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1121362:A605 RS12170
gene id: 1121362:A605_RS12170
uniprot id: M1N098
names: Similarity
messages: Belongs to the GARS family.

1121362:A605 RS07740
gene id: 1121362:A605_RS07740
uniprot id: M1MXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1121362:A605 RS00235
gene id: 1121362:A605_RS00235
uniprot id: M1NI41
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1121362:A605 RS09220
gene id: 1121362:A605_RS09220
uniprot id: M1NZ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1121362:A605 RS06135
gene id: 1121362:A605_RS06135
uniprot id: M1NXJ4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121362:A605 RS08255
gene id: 1121362:A605_RS08255
uniprot id: M1NMP4
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1121362:A605 RS12800
gene id: 1121362:A605_RS12800
uniprot id: M1PA34
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS04370
gene id: 1121362:A605_RS04370
uniprot id: M1MVV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1121362:A605 RS02290
gene id: 1121362:A605_RS02290
uniprot id: M1NJ97
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1121362:A605 RS10520
gene id: 1121362:A605_RS10520
uniprot id: M1NP05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1121362:A605 RS10960
gene id: 1121362:A605_RS10960
uniprot id: M1NUJ6
names: Similarity
messages: Belongs to the manganese catalase family.

1121362:A605 RS02695
gene id: 1121362:A605_RS02695
uniprot id: M1MV04
names: Similarity
messages: Belongs to the cytochrome P450 family.

1121362:A605 RS10560
gene id: 1121362:A605_RS10560
uniprot id: M1P8U0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1121362:A605 RS12360
gene id: 1121362:A605_RS12360
uniprot id: M1NVB3
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS04340
gene id: 1121362:A605_RS04340
uniprot id: M1NKD1
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS03805
gene id: 1121362:A605_RS03805
uniprot id: M1P519
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1121362:A605 RS04375
gene id: 1121362:A605_RS04375
uniprot id: M1NWK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1121362:A605 RS03550
gene id: 1121362:A605_RS03550
uniprot id: M1NW42
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1121362:A605 RS11700
gene id: 1121362:A605_RS11700
uniprot id: M1P9F4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121362:A605 RS08165
gene id: 1121362:A605_RS08165
uniprot id: M1NYN8
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS02545
gene id: 1121362:A605_RS02545
uniprot id: M1NVK0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1121362:A605 RS10945
gene id: 1121362:A605_RS10945
uniprot id: M1MZM4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121362:A605 RS09035
gene id: 1121362:A605_RS09035
uniprot id: M1NN36
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS06065
gene id: 1121362:A605_RS06065
uniprot id: M1P6B5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1121362:A605 RS01465
gene id: 1121362:A605_RS01465
uniprot id: M1MU95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1121362:A605 RS07910
gene id: 1121362:A605_RS07910
uniprot id: M1NMI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1121362:A605 RS05495
gene id: 1121362:A605_RS05495
uniprot id: M1NRG0
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS12810
gene id: 1121362:A605_RS12810
uniprot id: M1NQ74
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1121362:A605 RS05135
gene id: 1121362:A605_RS05135
uniprot id: M1P5W5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1121362:A605 RS07465
gene id: 1121362:A605_RS07465
uniprot id: M1NYB4
names: Similarity
messages: Belongs to the peptidase M18 family.

1121362:A605 RS12865
gene id: 1121362:A605_RS12865
uniprot id: M1N0U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121362:A605 RS11940
gene id: 1121362:A605_RS11940
uniprot id: M1N055
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1121362:A605 RS14595
gene id: 1121362:A605_RS14595
uniprot id: M1N1T5
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS00070
gene id: 1121362:A605_RS00070
uniprot id: M1NU61
names: Similarity
messages: Belongs to the PrpD family.

1121362:A605 RS08355
gene id: 1121362:A605_RS08355
uniprot id: M1P7L4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1121362:A605 RS06080
gene id: 1121362:A605_RS06080
uniprot id: M1MWT4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1121362:A605 RS04795
gene id: 1121362:A605_RS04795
uniprot id: M1NR13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1121362:A605 RS06305
gene id: 1121362:A605_RS06305
uniprot id: M1MWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS03290
gene id: 1121362:A605_RS03290
uniprot id: M1NJT8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1121362:A605 RS08985
gene id: 1121362:A605_RS08985
uniprot id: M1NN24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1121362:A605 RS10955
gene id: 1121362:A605_RS10955
uniprot id: M1P911
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1121362:A605 RS06140
gene id: 1121362:A605_RS06140
uniprot id: M1P6C3
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

1121362:A605 RS10985
gene id: 1121362:A605_RS10985
uniprot id: M1NUK1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1121362:A605 RS01850
gene id: 1121362:A605_RS01850
uniprot id: M1MUG1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1121362:A605 RS08900
gene id: 1121362:A605_RS08900
uniprot id: M1P7W1
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS02360
gene id: 1121362:A605_RS02360
uniprot id: M1P4D4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1121362:A605 RS05690
gene id: 1121362:A605_RS05690
uniprot id: M1P657
names: Similarity
messages: Belongs to the LOG family.

1121362:A605 RS08460
gene id: 1121362:A605_RS08460
uniprot id: M1NMS1
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1121362:A605 RS07980
gene id: 1121362:A605_RS07980
uniprot id: M1NSZ2
names: Similarity
messages: Belongs to the peptidase M24B family.

1121362:A605 RS11995
gene id: 1121362:A605_RS11995
uniprot id: M1N062
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1121362:A605 RS02410
gene id: 1121362:A605_RS02410
uniprot id: M1NJD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1121362:A605 RS11060
gene id: 1121362:A605_RS11060
uniprot id: M1NUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1121362:A605 RS03885
gene id: 1121362:A605_RS03885
uniprot id: M1NQI8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1121362:A605 RS08380
gene id: 1121362:A605_RS08380
uniprot id: M1NT51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1121362:A605 RS00975
gene id: 1121362:A605_RS00975
uniprot id: M1NNY2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1121362:A605 RS14115
gene id: 1121362:A605_RS14115
uniprot id: M1N1H8
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS02540
gene id: 1121362:A605_RS02540
uniprot id: M1MUX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1121362:A605 RS07985
gene id: 1121362:A605_RS07985
uniprot id: M1NMJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1121362:A605 RS13320
gene id: 1121362:A605_RS13320
uniprot id: M1NQG5
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

1121362:A605 RS01780
gene id: 1121362:A605_RS01780
uniprot id: M1P3W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1121362:A605 RS02125
gene id: 1121362:A605_RS02125
uniprot id: M1NVB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1121362:A605 RS09680
gene id: 1121362:A605_RS09680
uniprot id: M1MYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1121362:A605 RS12970
gene id: 1121362:A605_RS12970
uniprot id: M1N0V9
names: Similarity
messages: Belongs to the peptidase C56 family.

1121362:A605 RS09415
gene id: 1121362:A605_RS09415
uniprot id: M1NZC0
names: Similarity
messages: Belongs to the IMPACT family.

1121362:A605 RS01935
gene id: 1121362:A605_RS01935
uniprot id: M1P408
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1121362:A605 RS02640
gene id: 1121362:A605_RS02640
uniprot id: M1NJH5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1121362:A605 RS01150
gene id: 1121362:A605_RS01150
uniprot id: M1P3H7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1121362:A605 RS08600
gene id: 1121362:A605_RS08600
uniprot id: M1P7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1121362:A605 RS15790
gene id: 1121362:A605_RS15790
uniprot id: M1P5C7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS05410
gene id: 1121362:A605_RS05410
uniprot id: M1NX61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1121362:A605 RS02520
gene id: 1121362:A605_RS02520
uniprot id: M1NVJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1121362:A605 RS00100
gene id: 1121362:A605_RS00100
uniprot id: M1P2Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1121362:A605 RS09540
gene id: 1121362:A605_RS09540
uniprot id: M1P890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1121362:A605 RS03975
gene id: 1121362:A605_RS03975
uniprot id: M1MVN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1121362:A605 RS04390
gene id: 1121362:A605_RS04390
uniprot id: M1NKE1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1121362:A605 RS06120
gene id: 1121362:A605_RS06120
uniprot id: M1NRT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS12660
gene id: 1121362:A605_RS12660
uniprot id: M1NQ47
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1121362:A605 RS01760
gene id: 1121362:A605_RS01760
uniprot id: M1NPC0
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1121362:A605 RS12120
gene id: 1121362:A605_RS12120
uniprot id: M1N087
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1121362:A605 RS01145
gene id: 1121362:A605_RS01145
uniprot id: M1NUQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1121362:A605 RS08840
gene id: 1121362:A605_RS08840
uniprot id: M1MYD1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1121362:A605 RS01320
gene id: 1121362:A605_RS01320
uniprot id: M1NUU0
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS11145
gene id: 1121362:A605_RS11145
uniprot id: M1MZR2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1121362:A605 RS12000
gene id: 1121362:A605_RS12000
uniprot id: M1P0P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1121362:A605 RS13415
gene id: 1121362:A605_RS13415
uniprot id: M1NVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS07590
gene id: 1121362:A605_RS07590
uniprot id: M1MXP5
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS04515
gene id: 1121362:A605_RS04515
uniprot id: M1NQV8
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS06255
gene id: 1121362:A605_RS06255
uniprot id: M1MWW6
names: Similarity
messages: Belongs to the UPF0045 family.

1121362:A605 RS01720
gene id: 1121362:A605_RS01720
uniprot id: M1MUD9
names: Similarity
messages: Belongs to the GSP E family.

1121362:A605 RS14135
gene id: 1121362:A605_RS14135
uniprot id: M1NQX3
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

1121362:A605 RS00825
gene id: 1121362:A605_RS00825
uniprot id: M1NIE3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121362:A605 RS01230
gene id: 1121362:A605_RS01230
uniprot id: M1NP30
names: Similarity
messages: Belongs to the peptidase M13 family.

1121362:A605 RS00600
gene id: 1121362:A605_RS00600
uniprot id: M1NNR5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1121362:A605 RS13005
gene id: 1121362:A605_RS13005
uniprot id: M1PA67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1121362:A605 RS02630
gene id: 1121362:A605_RS02630
uniprot id: M1P4H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1121362:A605 RS04310
gene id: 1121362:A605_RS04310
uniprot id: M1NQS0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121362:A605 RS10120
gene id: 1121362:A605_RS10120
uniprot id: M1P8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1121362:A605 RS02650
gene id: 1121362:A605_RS02650
uniprot id: M1NVL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1121362:A605 RS06415
gene id: 1121362:A605_RS06415
uniprot id: M1P6I7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1121362:A605 RS11220
gene id: 1121362:A605_RS11220
uniprot id: M1MZS7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1121362:A605 RS00095
gene id: 1121362:A605_RS00095
uniprot id: M1NU64
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS04335
gene id: 1121362:A605_RS04335
uniprot id: M1NQS6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1121362:A605 RS14065
gene id: 1121362:A605_RS14065
uniprot id: M1NQV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1121362:A605 RS04180
gene id: 1121362:A605_RS04180
uniprot id: M1NQP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1121362:A605 RS12945
gene id: 1121362:A605_RS12945
uniprot id: M1P185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1121362:A605 RS05820
gene id: 1121362:A605_RS05820
uniprot id: M1NL79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS09770
gene id: 1121362:A605_RS09770
uniprot id: M1NTY4
names: Similarity
messages: Belongs to the CobT family.

1121362:A605 RS05910
gene id: 1121362:A605_RS05910
uniprot id: M1P697
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1121362:A605 RS03280
gene id: 1121362:A605_RS03280
uniprot id: M1P4S9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1121362:A605 RS14455
gene id: 1121362:A605_RS14455
uniprot id: M1NWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121362:A605 RS08195
gene id: 1121362:A605_RS08195
uniprot id: M1P7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1121362:A605 RS06180
gene id: 1121362:A605_RS06180
uniprot id: M1MWV2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1121362:A605 RS14575
gene id: 1121362:A605_RS14575
uniprot id: M1P221
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09405
gene id: 1121362:A605_RS09405
uniprot id: M1NNC0
names: Similarity
messages: Belongs to the HSP15 family.

1121362:A605 RS11900
gene id: 1121362:A605_RS11900
uniprot id: M1N050
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121362:A605 RS09625
gene id: 1121362:A605_RS09625
uniprot id: M1NNH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1121362:A605 RS05670
gene id: 1121362:A605_RS05670
uniprot id: M1NRK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1121362:A605 RS03210
gene id: 1121362:A605_RS03210
uniprot id: M1NQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1121362:A605 RS11160
gene id: 1121362:A605_RS11160
uniprot id: M1NUN3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1121362:A605 RS05085
gene id: 1121362:A605_RS05085
uniprot id: M1P5V5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1121362:A605 RS08185
gene id: 1121362:A605_RS08185
uniprot id: M1MY09
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1121362:A605 RS10720
gene id: 1121362:A605_RS10720
uniprot id: M1NP36
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1121362:A605 RS11330
gene id: 1121362:A605_RS11330
uniprot id: M1NUQ9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1121362:A605 RS09465
gene id: 1121362:A605_RS09465
uniprot id: M1NZC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1121362:A605 RS00930
gene id: 1121362:A605_RS00930
uniprot id: M1NIG0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1121362:A605 RS06490
gene id: 1121362:A605_RS06490
uniprot id: M1P6K2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121362:A605 RS05925
gene id: 1121362:A605_RS05925
uniprot id: M1MWQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1121362:A605 RS08525
gene id: 1121362:A605_RS08525
uniprot id: M1P7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1121362:A605 RS02000
gene id: 1121362:A605_RS02000
uniprot id: M1MUI6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1121362:A605 RS08800
gene id: 1121362:A605_RS08800
uniprot id: M1P7T9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS02505
gene id: 1121362:A605_RS02505
uniprot id: M1NPU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1121362:A605 RS06905
gene id: 1121362:A605_RS06905
uniprot id: M1NLU5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1121362:A605 RS09750
gene id: 1121362:A605_RS09750
uniprot id: M1NNK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1121362:A605 RS00540
gene id: 1121362:A605_RS00540
uniprot id: M1NUD9
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

1121362:A605 RS00830
gene id: 1121362:A605_RS00830
uniprot id: M1MU02
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121362:A605 RS03205
gene id: 1121362:A605_RS03205
uniprot id: M1P4R6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1121362:A605 RS03295
gene id: 1121362:A605_RS03295
uniprot id: M1MVB5
names: Similarity
messages: Belongs to the PrpD family.

1121362:A605 RS04840
gene id: 1121362:A605_RS04840
uniprot id: M1P5P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1121362:A605 RS06235
gene id: 1121362:A605_RS06235
uniprot id: M1NXL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1121362:A605 RS07695
gene id: 1121362:A605_RS07695
uniprot id: M1NYF4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1121362:A605 RS02155
gene id: 1121362:A605_RS02155
uniprot id: M1P469
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS05635
gene id: 1121362:A605_RS05635
uniprot id: M1NXA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1121362:A605 RS11460
gene id: 1121362:A605_RS11460
uniprot id: M1NPE7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1121362:A605 RS02775
gene id: 1121362:A605_RS02775
uniprot id: M1NVP1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS01450
gene id: 1121362:A605_RS01450
uniprot id: M1P3P2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS02750
gene id: 1121362:A605_RS02750
uniprot id: M1NVN6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1121362:A605 RS10815
gene id: 1121362:A605_RS10815
uniprot id: M1NP49
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS14500
gene id: 1121362:A605_RS14500
uniprot id: M1PB05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1121362:A605 RS09580
gene id: 1121362:A605_RS09580
uniprot id: M1MYV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS06965
gene id: 1121362:A605_RS06965
uniprot id: M1NY06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS02740
gene id: 1121362:A605_RS02740
uniprot id: M1NJJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1121362:A605 RS09830
gene id: 1121362:A605_RS09830
uniprot id: M1MZ21
names: Similarity
messages: Belongs to the glutamine synthetase family.

1121362:A605 RS02460
gene id: 1121362:A605_RS02460
uniprot id: M1NJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1121362:A605 RS00745
gene id: 1121362:A605_RS00745
uniprot id: M1P3A2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1121362:A605 RS09590
gene id: 1121362:A605_RS09590
uniprot id: M1P8A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1121362:A605 RS07345
gene id: 1121362:A605_RS07345
uniprot id: M1P738
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS02930
gene id: 1121362:A605_RS02930
uniprot id: M1P4M3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1121362:A605 RS03760
gene id: 1121362:A605_RS03760
uniprot id: M1NQG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

1121362:A605 RS10920
gene id: 1121362:A605_RS10920
uniprot id: M1MZL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1121362:A605 RS05835
gene id: 1121362:A605_RS05835
uniprot id: M1P684
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS12015
gene id: 1121362:A605_RS12015
uniprot id: M1NPP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1121362:A605 RS11275
gene id: 1121362:A605_RS11275
uniprot id: M1P0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121362:A605 RS07025
gene id: 1121362:A605_RS07025
uniprot id: M1NLX4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS02870
gene id: 1121362:A605_RS02870
uniprot id: M1MV35
names: Similarity
messages: Belongs to the WXG100 family.

1121362:A605 RS03740
gene id: 1121362:A605_RS03740
uniprot id: M1NK12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1121362:A605 RS09365
gene id: 1121362:A605_RS09365
uniprot id: M1MYQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1121362:A605 RS10465
gene id: 1121362:A605_RS10465
uniprot id: M1NUA7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1121362:A605 RS11175
gene id: 1121362:A605_RS11175
uniprot id: M1P0A5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1121362:A605 RS13890
gene id: 1121362:A605_RS13890
uniprot id: M1NQS5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1121362:A605 RS07605
gene id: 1121362:A605_RS07605
uniprot id: M1NST5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS08510
gene id: 1121362:A605_RS08510
uniprot id: M1NMT1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1121362:A605 RS01065
gene id: 1121362:A605_RS01065
uniprot id: M1MU37
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1121362:A605 RS04780
gene id: 1121362:A605_RS04780
uniprot id: M1MW54
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS06720
gene id: 1121362:A605_RS06720
uniprot id: M1NS70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1121362:A605 RS04510
gene id: 1121362:A605_RS04510
uniprot id: M1P5G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1121362:A605 RS03010
gene id: 1121362:A605_RS03010
uniprot id: M1NQ31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121362:A605 RS04985
gene id: 1121362:A605_RS04985
uniprot id: M1NR67
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1121362:A605 RS08370
gene id: 1121362:A605_RS08370
uniprot id: M1MY42
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1121362:A605 RS03710
gene id: 1121362:A605_RS03710
uniprot id: M1NQF8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1121362:A605 RS09840
gene id: 1121362:A605_RS09840
uniprot id: M1P8F6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1121362:A605 RS14095
gene id: 1121362:A605_RS14095
uniprot id: M1P1S9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121362:A605 RS02070
gene id: 1121362:A605_RS02070
uniprot id: M1MUK2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1121362:A605 RS06950
gene id: 1121362:A605_RS06950
uniprot id: M1NSC6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS02150
gene id: 1121362:A605_RS02150
uniprot id: M1NVC2
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09215
gene id: 1121362:A605_RS09215
uniprot id: M1MYM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1121362:A605 RS06455
gene id: 1121362:A605_RS06455
uniprot id: M1MX03
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1121362:A605 RS05565
gene id: 1121362:A605_RS05565
uniprot id: M1P636
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1121362:A605 RS14275
gene id: 1121362:A605_RS14275
uniprot id: M1PAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1121362:A605 RS11780
gene id: 1121362:A605_RS11780
uniprot id: M1NV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121362:A605 RS08615
gene id: 1121362:A605_RS08615
uniprot id: M1MY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1121362:A605 RS10050
gene id: 1121362:A605_RS10050
uniprot id: M1NU51
names: Similarity
messages: Belongs to the glutamine synthetase family.

1121362:A605 RS05315
gene id: 1121362:A605_RS05315
uniprot id: M1NRC9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1121362:A605 RS08180
gene id: 1121362:A605_RS08180
uniprot id: M1NMN1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1121362:A605 RS12565
gene id: 1121362:A605_RS12565
uniprot id: M1N0N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1121362:A605 RS11350
gene id: 1121362:A605_RS11350
uniprot id: M1P983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121362:A605 RS14235
gene id: 1121362:A605_RS14235
uniprot id: M1NQZ4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1121362:A605 RS07290
gene id: 1121362:A605_RS07290
uniprot id: M1NY62
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1121362:A605 RS11985
gene id: 1121362:A605_RS11985
uniprot id: M1NV30
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1121362:A605 RS08335
gene id: 1121362:A605_RS08335
uniprot id: M1NT43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1121362:A605 RS06900
gene id: 1121362:A605_RS06900
uniprot id: M1NSB1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1121362:A605 RS14785
gene id: 1121362:A605_RS14785
uniprot id: M1MX33
names: Subcellular Location Annotation
messages: Secreted

1121362:A605 RS11005
gene id: 1121362:A605_RS11005
uniprot id: M1P919
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS04475
gene id: 1121362:A605_RS04475
uniprot id: M1MVX7
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS03600
gene id: 1121362:A605_RS03600
uniprot id: M1NW49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1121362:A605 RS12825
gene id: 1121362:A605_RS12825
uniprot id: M1PA39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1121362:A605 RS02980
gene id: 1121362:A605_RS02980
uniprot id: M1P4M9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1121362:A605 RS15760
gene id: 1121362:A605_RS15760
uniprot id: M1NIW9
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1121362:A605 RS12915
gene id: 1121362:A605_RS12915
uniprot id: M1N0V1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121362:A605 RS12935
gene id: 1121362:A605_RS12935
uniprot id: M1NQ97
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1121362:A605 RS00475
gene id: 1121362:A605_RS00475
uniprot id: M1NNP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1121362:A605 RS06410
gene id: 1121362:A605_RS06410
uniprot id: M1NXP5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1121362:A605 RS11255
gene id: 1121362:A605_RS11255
uniprot id: M1P965
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1121362:A605 RS02275
gene id: 1121362:A605_RS02275
uniprot id: M1NVF2
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS12630
gene id: 1121362:A605_RS12630
uniprot id: M1NVJ0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1121362:A605 RS09810
gene id: 1121362:A605_RS09810
uniprot id: M1NZK7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1121362:A605 RS11375
gene id: 1121362:A605_RS11375
uniprot id: M1P987
names: Similarity
messages: Belongs to the peptidase M1 family.

1121362:A605 RS02580
gene id: 1121362:A605_RS02580
uniprot id: M1NPW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1121362:A605 RS09555
gene id: 1121362:A605_RS09555
uniprot id: M1MYV0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1121362:A605 RS04965
gene id: 1121362:A605_RS04965
uniprot id: M1NKT6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1121362:A605 RS14000
gene id: 1121362:A605_RS14000
uniprot id: M1P1Q9
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09980
gene id: 1121362:A605_RS09980
uniprot id: M1NNR6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1121362:A605 RS07005
gene id: 1121362:A605_RS07005
uniprot id: M1MX98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS12200
gene id: 1121362:A605_RS12200
uniprot id: M1P0T5
names: Similarity
messages: Belongs to the DSD1 family.

1121362:A605 RS06505
gene id: 1121362:A605_RS06505
uniprot id: M1MX10
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS14715
gene id: 1121362:A605_RS14715
uniprot id: M1NIS0
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1121362:A605 RS04215
gene id: 1121362:A605_RS04215
uniprot id: M1NKA4
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1121362:A605 RS09075
gene id: 1121362:A605_RS09075
uniprot id: M1P7Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1121362:A605 RS04000
gene id: 1121362:A605_RS04000
uniprot id: M1MVP3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1121362:A605 RS07680
gene id: 1121362:A605_RS07680
uniprot id: M1NSU8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1121362:A605 RS00360
gene id: 1121362:A605_RS00360
uniprot id: M1P330
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1121362:A605 RS02445
gene id: 1121362:A605_RS02445
uniprot id: M1NVI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1121362:A605 RS07240
gene id: 1121362:A605_RS07240
uniprot id: M1MXF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1121362:A605 RS07310
gene id: 1121362:A605_RS07310
uniprot id: M1MXH0
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS14560
gene id: 1121362:A605_RS14560
uniprot id: M1NWK0
names: Similarity
messages: Belongs to the CsoR family.

1121362:A605 RS11080
gene id: 1121362:A605_RS11080
uniprot id: M1P934
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1121362:A605 RS13225
gene id: 1121362:A605_RS13225
uniprot id: M1N102
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS07490
gene id: 1121362:A605_RS07490
uniprot id: M1NYC4
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS12575
gene id: 1121362:A605_RS12575
uniprot id: M1P9Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1121362:A605 RS09775
gene id: 1121362:A605_RS09775
uniprot id: M1NNK9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1121362:A605 RS11485
gene id: 1121362:A605_RS11485
uniprot id: M1NPF1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1121362:A605 RS14360
gene id: 1121362:A605_RS14360
uniprot id: M1N1N6
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS03515
gene id: 1121362:A605_RS03515
uniprot id: M1NJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121362:A605 RS01535
gene id: 1121362:A605_RS01535
uniprot id: M1NP78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1121362:A605 RS11670
gene id: 1121362:A605_RS11670
uniprot id: M1P9E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1121362:A605 RS13840
gene id: 1121362:A605_RS13840
uniprot id: M1NQR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1121362:A605 RS04385
gene id: 1121362:A605_RS04385
uniprot id: M1NQT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1121362:A605 RS02735
gene id: 1121362:A605_RS02735
uniprot id: M1NPY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1121362:A605 RS11775
gene id: 1121362:A605_RS11775
uniprot id: M1P9G8
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS15280
gene id: 1121362:A605_RS15280
uniprot id: M1NM68
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1121362:A605 RS13080
gene id: 1121362:A605_RS13080
uniprot id: M1PA80
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS11885
gene id: 1121362:A605_RS11885
uniprot id: M1P9J1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1121362:A605 RS01180
gene id: 1121362:A605_RS01180
uniprot id: M1NP21
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1121362:A605 RS05170
gene id: 1121362:A605_RS05170
uniprot id: M1NKX1
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1121362:A605 RS09015
gene id: 1121362:A605_RS09015
uniprot id: M1MYG9
names: Similarity
messages: Belongs to the UPF0102 family.

1121362:A605 RS01245
gene id: 1121362:A605_RS01245
uniprot id: M1NUS3
names: Similarity
messages: Belongs to the glutamate synthase family.

1121362:A605 RS10045
gene id: 1121362:A605_RS10045
uniprot id: M1P8K7
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1121362:A605 RS13645
gene id: 1121362:A605_RS13645
uniprot id: M1P1J6
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09270
gene id: 1121362:A605_RS09270
uniprot id: M1NZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1121362:A605 RS14050
gene id: 1121362:A605_RS14050
uniprot id: M1P1R8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS00815
gene id: 1121362:A605_RS00815
uniprot id: M1P3B8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1121362:A605 RS04140
gene id: 1121362:A605_RS04140
uniprot id: M1MVR2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1121362:A605 RS12065
gene id: 1121362:A605_RS12065
uniprot id: M1NPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1121362:A605 RS09645
gene id: 1121362:A605_RS09645
uniprot id: M1NTV7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1121362:A605 RS01525
gene id: 1121362:A605_RS01525
uniprot id: M1NUY1
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS08730
gene id: 1121362:A605_RS08730
uniprot id: M1NTB9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1121362:A605 RS10105
gene id: 1121362:A605_RS10105
uniprot id: M1NNU8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1121362:A605 RS00605
gene id: 1121362:A605_RS00605
uniprot id: M1NIA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121362:A605 RS06030
gene id: 1121362:A605_RS06030
uniprot id: M1NXH5
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS04440
gene id: 1121362:A605_RS04440
uniprot id: M1NKF3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1121362:A605 RS01645
gene id: 1121362:A605_RS01645
uniprot id: M1NIT0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1121362:A605 RS09905
gene id: 1121362:A605_RS09905
uniprot id: M1NNP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS14160
gene id: 1121362:A605_RS14160
uniprot id: M1NQX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1121362:A605 RS03770
gene id: 1121362:A605_RS03770
uniprot id: M1MVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1121362:A605 RS12520
gene id: 1121362:A605_RS12520
uniprot id: M1P111
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS08585
gene id: 1121362:A605_RS08585
uniprot id: M1NMU5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1121362:A605 RS09920
gene id: 1121362:A605_RS09920
uniprot id: M1P8H1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1121362:A605 RS06565
gene id: 1121362:A605_RS06565
uniprot id: M1P6L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1121362:A605 RS12730
gene id: 1121362:A605_RS12730
uniprot id: M1NVL4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1121362:A605 RS14150
gene id: 1121362:A605_RS14150
uniprot id: M1PAS0
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

1121362:A605 RS04745
gene id: 1121362:A605_RS04745
uniprot id: M1NR02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1121362:A605 RS10855
gene id: 1121362:A605_RS10855
uniprot id: M1P8Z5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1121362:A605 RS08975
gene id: 1121362:A605_RS08975
uniprot id: M1P7X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1121362:A605 RS02105
gene id: 1121362:A605_RS02105
uniprot id: M1P458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS14515
gene id: 1121362:A605_RS14515
uniprot id: M1N1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1121362:A605 RS06105
gene id: 1121362:A605_RS06105
uniprot id: M1MWT8
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09850
gene id: 1121362:A605_RS09850
uniprot id: M1NNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1121362:A605 RS01985
gene id: 1121362:A605_RS01985
uniprot id: M1P424
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS12330
gene id: 1121362:A605_RS12330
uniprot id: M1P0W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

1121362:A605 RS07765
gene id: 1121362:A605_RS07765
uniprot id: M1MXS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1121362:A605 RS12745
gene id: 1121362:A605_RS12745
uniprot id: M1P151
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1121362:A605 RS06745
gene id: 1121362:A605_RS06745
uniprot id: M1NS74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1121362:A605 RS06220
gene id: 1121362:A605_RS06220
uniprot id: M1NRW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1121362:A605 RS14735
gene id: 1121362:A605_RS14735
uniprot id: M1NPU4
names: Similarity
messages: Belongs to the asp23 family.

1121362:A605 RS02880
gene id: 1121362:A605_RS02880
uniprot id: M1P4L3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1121362:A605 RS04555
gene id: 1121362:A605_RS04555
uniprot id: M1MVZ6
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1121362:A605 RS08530
gene id: 1121362:A605_RS08530
uniprot id: M1NT81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1121362:A605 RS08650
gene id: 1121362:A605_RS08650
uniprot id: M1P7R0
names: Similarity
messages: Belongs to the YciI family.

1121362:A605 RS07990
gene id: 1121362:A605_RS07990
uniprot id: M1MXW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS06070
gene id: 1121362:A605_RS06070
uniprot id: M1NRS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1121362:A605 RS11740
gene id: 1121362:A605_RS11740
uniprot id: M1N020
names: Similarity
messages: Belongs to the peptidase S58 family.

1121362:A605 RS13095
gene id: 1121362:A605_RS13095
uniprot id: M1N0X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1121362:A605 RS11280
gene id: 1121362:A605_RS11280
uniprot id: M1P970
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121362:A605 RS04350
gene id: 1121362:A605_RS04350
uniprot id: M1NWK1
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS11440
gene id: 1121362:A605_RS11440
uniprot id: M1MZW0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1121362:A605 RS05625
gene id: 1121362:A605_RS05625
uniprot id: M1NL46
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09130
gene id: 1121362:A605_RS09130
uniprot id: M1NTJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1121362:A605 RS03655
gene id: 1121362:A605_RS03655
uniprot id: M1P4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS00185
gene id: 1121362:A605_RS00185
uniprot id: M1NNK1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

1121362:A605 RS07940
gene id: 1121362:A605_RS07940
uniprot id: M1MXV7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1121362:A605 RS00325
gene id: 1121362:A605_RS00325
uniprot id: M1NU98
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS14350
gene id: 1121362:A605_RS14350
uniprot id: M1NWF6
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1121362:A605 RS09745
gene id: 1121362:A605_RS09745
uniprot id: M1NTX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1121362:A605 RS12925
gene id: 1121362:A605_RS12925
uniprot id: M1PA54
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1121362:A605 RS06155
gene id: 1121362:A605_RS06155
uniprot id: M1MWU7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121362:A605 RS06700
gene id: 1121362:A605_RS06700
uniprot id: M1NLP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1121362:A605 RS05335
gene id: 1121362:A605_RS05335
uniprot id: M1P601
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1121362:A605 RS12930
gene id: 1121362:A605_RS12930
uniprot id: M1NVP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1121362:A605 RS13115
gene id: 1121362:A605_RS13115
uniprot id: M1NVS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1121362:A605 RS01440
gene id: 1121362:A605_RS01440
uniprot id: M1MU90
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS10185
gene id: 1121362:A605_RS10185
uniprot id: M1NNV7
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1121362:A605 RS10635
gene id: 1121362:A605_RS10635
uniprot id: M1P8V5
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS14570
gene id: 1121362:A605_RS14570
uniprot id: M1N1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1121362:A605 RS13575
gene id: 1121362:A605_RS13575
uniprot id: M1N161
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1121362:A605 RS09210
gene id: 1121362:A605_RS09210
uniprot id: M1NN77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS04075
gene id: 1121362:A605_RS04075
uniprot id: M1P569
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS07790
gene id: 1121362:A605_RS07790
uniprot id: M1MXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1121362:A605 RS06175
gene id: 1121362:A605_RS06175
uniprot id: M1NLD9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1121362:A605 RS07130
gene id: 1121362:A605_RS07130
uniprot id: M1MXD0
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS09800
gene id: 1121362:A605_RS09800
uniprot id: M1NNL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1121362:A605 RS10835
gene id: 1121362:A605_RS10835
uniprot id: M1NUH3
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1121362:A605 RS12455
gene id: 1121362:A605_RS12455
uniprot id: M1NVD6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1121362:A605 RS02350
gene id: 1121362:A605_RS02350
uniprot id: M1NVH1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1121362:A605 RS11165
gene id: 1121362:A605_RS11165
uniprot id: M1NPA0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1121362:A605 RS07860
gene id: 1121362:A605_RS07860
uniprot id: M1NMH3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1121362:A605 RS08670
gene id: 1121362:A605_RS08670
uniprot id: M1NYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1121362:A605 RS13795
gene id: 1121362:A605_RS13795
uniprot id: M1N1A5
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1121362:A605 RS06085
gene id: 1121362:A605_RS06085
uniprot id: M1NXI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1121362:A605 RS04635
gene id: 1121362:A605_RS04635
uniprot id: M1NWQ7
names: Cofactor
messages: Can also use Mn(2+) ion.

1121362:A605 RS05275
gene id: 1121362:A605_RS05275
uniprot id: M1MWE5
names: Caution
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS08490
gene id: 1121362:A605_RS08490
uniprot id: M1MY67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1121362:A605 RS03385
gene id: 1121362:A605_RS03385
uniprot id: M1P4U3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1121362:A605 RS04280
gene id: 1121362:A605_RS04280
uniprot id: M1P5B7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121362:A605 RS05310
gene id: 1121362:A605_RS05310
uniprot id: M1P5Z5
names: Similarity
messages: Belongs to the catalase family.

1121362:A605 RS09305
gene id: 1121362:A605_RS09305
uniprot id: M1NTN0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1121362:A605 RS05520
gene id: 1121362:A605_RS05520
uniprot id: M1NRG6
names: Similarity
messages: Belongs to the TPP enzyme family.

1121362:A605 RS00740
gene id: 1121362:A605_RS00740
uniprot id: M1NUH8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1121362:A605 RS09180
gene id: 1121362:A605_RS09180
uniprot id: M1NTK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121362:A605 RS02605
gene id: 1121362:A605_RS02605
uniprot id: M1NPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1121362:A605 RS14335
gene id: 1121362:A605_RS14335
uniprot id: M1N1N0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121362:A605 RS08680
gene id: 1121362:A605_RS08680
uniprot id: M1NTA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS09755
gene id: 1121362:A605_RS09755
uniprot id: M1MZ04
names: Similarity
messages: Belongs to the asparagine synthetase family.

1121362:A605 RS00390
gene id: 1121362:A605_RS00390
uniprot id: M1NUB3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1121362:A605 RS04135
gene id: 1121362:A605_RS04135
uniprot id: M1NK87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1121362:A605 RS03450
gene id: 1121362:A605_RS03450
uniprot id: M1MVE5
names: Similarity
messages: Belongs to the AccD/PCCB family.

1121362:A605 RS11810
gene id: 1121362:A605_RS11810
uniprot id: M1NPL2
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1121362:A605 RS06960
gene id: 1121362:A605_RS06960
uniprot id: M1MX93
names: Similarity
messages: Belongs to the UPF0434 family.

1121362:A605 RS09670
gene id: 1121362:A605_RS09670
uniprot id: M1NTW2
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1121362:A605 RS06765
gene id: 1121362:A605_RS06765
uniprot id: M1P6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS02500
gene id: 1121362:A605_RS02500
uniprot id: M1P4F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1121362:A605 RS12415
gene id: 1121362:A605_RS12415
uniprot id: M1N0F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1121362:A605 RS03320
gene id: 1121362:A605_RS03320
uniprot id: M1MVC0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1121362:A605 RS03510
gene id: 1121362:A605_RS03510
uniprot id: M1NQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121362:A605 RS05735
gene id: 1121362:A605_RS05735
uniprot id: M1P665
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121362:A605 RS01725
gene id: 1121362:A605_RS01725
uniprot id: M1NV26
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS11805
gene id: 1121362:A605_RS11805
uniprot id: M1NV05
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1121362:A605 RS02745
gene id: 1121362:A605_RS02745
uniprot id: M1MV12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1121362:A605 RS07755
gene id: 1121362:A605_RS07755
uniprot id: M1NSV9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1121362:A605 RS12495
gene id: 1121362:A605_RS12495
uniprot id: M1P105
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1121362:A605 RS02385
gene id: 1121362:A605_RS02385
uniprot id: M1NJD1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1121362:A605 RS08190
gene id: 1121362:A605_RS08190
uniprot id: M1NYP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1121362:A605 RS07010
gene id: 1121362:A605_RS07010
uniprot id: M1NY12
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1121362:A605 RS00440
gene id: 1121362:A605_RS00440
uniprot id: M1NUC2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1121362:A605 RS07450
gene id: 1121362:A605_RS07450
uniprot id: M1NSQ0
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1121362:A605 RS02380
gene id: 1121362:A605_RS02380
uniprot id: M1NPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1121362:A605 RS12100
gene id: 1121362:A605_RS12100
uniprot id: M1P0R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1121362:A605 RS03120
gene id: 1121362:A605_RS03120
uniprot id: M1MV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1121362:A605 RS12355
gene id: 1121362:A605_RS12355
uniprot id: M1P9T6
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

1121362:A605 RS04940
gene id: 1121362:A605_RS04940
uniprot id: M1MW94
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1121362:A605 RS10710
gene id: 1121362:A605_RS10710
uniprot id: M1P8W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121362:A605 RS12675
gene id: 1121362:A605_RS12675
uniprot id: M1PA15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121362:A605 RS07220
gene id: 1121362:A605_RS07220
uniprot id: M1NY47
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS13655
gene id: 1121362:A605_RS13655
uniprot id: M1NW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1121362:A605 RS01510
gene id: 1121362:A605_RS01510
uniprot id: M1NP73
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1121362:A605 RS04630
gene id: 1121362:A605_RS04630
uniprot id: M1MW16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121362:A605 RS11990
gene id: 1121362:A605_RS11990
uniprot id: M1NPP2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1121362:A605 RS01595
gene id: 1121362:A605_RS01595
uniprot id: M1MUB6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS00120
gene id: 1121362:A605_RS00120
uniprot id: M1NU67
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS04240
gene id: 1121362:A605_RS04240
uniprot id: M1NKB0
names: Similarity
messages: Belongs to the FPG family.

1121362:A605 RS01610
gene id: 1121362:A605_RS01610
uniprot id: M1NP89
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121362:A605 RS06715
gene id: 1121362:A605_RS06715
uniprot id: M1P6P1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1121362:A605 RS01215
gene id: 1121362:A605_RS01215
uniprot id: M1MU59
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121362:A605 RS01505
gene id: 1121362:A605_RS01505
uniprot id: M1P3Q4
names: Similarity
messages: Belongs to the Dps family.

1121362:A605 RS01920
gene id: 1121362:A605_RS01920
uniprot id: M1NIZ4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1121362:A605 RS01395
gene id: 1121362:A605_RS01395
uniprot id: M1NP57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1121362:A605 RS02940
gene id: 1121362:A605_RS02940
uniprot id: M1NJM4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1121362:A605 RS00255
gene id: 1121362:A605_RS00255
uniprot id: M1P311
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS01075
gene id: 1121362:A605_RS01075
uniprot id: M1P3G3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1121362:A605 RS11555
gene id: 1121362:A605_RS11555
uniprot id: M1P0G9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1121362:A605 RS01265
gene id: 1121362:A605_RS01265
uniprot id: M1MU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

1121362:A605 RS08420
gene id: 1121362:A605_RS08420
uniprot id: M1NYS8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1121362:A605 RS06820
gene id: 1121362:A605_RS06820
uniprot id: M1P6R6
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS07225
gene id: 1121362:A605_RS07225
uniprot id: M1P710
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS05475
gene id: 1121362:A605_RS05475
uniprot id: M1NL19
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1121362:A605 RS05675
gene id: 1121362:A605_RS05675
uniprot id: M1NL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1121362:A605 RS10450
gene id: 1121362:A605_RS10450
uniprot id: M1MZE5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1121362:A605 RS12780
gene id: 1121362:A605_RS12780
uniprot id: M1NVM1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121362:A605 RS00065
gene id: 1121362:A605_RS00065
uniprot id: M1MTL8
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

1121362:A605 RS07945
gene id: 1121362:A605_RS07945
uniprot id: M1NYJ8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1121362:A605 RS07930
gene id: 1121362:A605_RS07930
uniprot id: M1NSY5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1121362:A605 RS07715
gene id: 1121362:A605_RS07715
uniprot id: M1MXR5
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS12465
gene id: 1121362:A605_RS12465
uniprot id: M1N0G0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1121362:A605 RS05460
gene id: 1121362:A605_RS05460
uniprot id: M1NX68
names: Subcellular Location Annotation
messages: Membrane

1121362:A605 RS08045
gene id: 1121362:A605_RS08045
uniprot id: M1NYL6
names: Subcellular Location Annotation
messages: Membrane