1121335:CST RS09685
gene id: 1121335:CST_RS09685
uniprot id: L7VLI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1121335:CST RS09375
gene id: 1121335:CST_RS09375
uniprot id: L7VQ97
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1121335:CST RS01540
gene id: 1121335:CST_RS01540
uniprot id: L7VH69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1121335:CST RS12365
gene id: 1121335:CST_RS12365
uniprot id: L7VVK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1121335:CST RS10450
gene id: 1121335:CST_RS10450
uniprot id: L7VRB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1121335:CST RS10240
gene id: 1121335:CST_RS10240
uniprot id: L7VQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1121335:CST RS12690
gene id: 1121335:CST_RS12690
uniprot id: L7VSU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS12325
gene id: 1121335:CST_RS12325
uniprot id: L7VMY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1121335:CST RS04940
gene id: 1121335:CST_RS04940
uniprot id: L7VNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS12680
gene id: 1121335:CST_RS12680
uniprot id: L7VSD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1121335:CST RS11500
gene id: 1121335:CST_RS11500
uniprot id: L7VMG8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1121335:CST RS11705
gene id: 1121335:CST_RS11705
uniprot id: L7VSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1121335:CST RS02700
gene id: 1121335:CST_RS02700
uniprot id: L7VLL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1121335:CST RS04190
gene id: 1121335:CST_RS04190
uniprot id: L7VIK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1121335:CST RS08395
gene id: 1121335:CST_RS08395
uniprot id: L7VQU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1121335:CST RS03150
gene id: 1121335:CST_RS03150
uniprot id: L7VQ55
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1121335:CST RS01255
gene id: 1121335:CST_RS01255
uniprot id: L7VKV3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1121335:CST RS09430
gene id: 1121335:CST_RS09430
uniprot id: L7VTT2
names: Similarity
messages: Belongs to the TrpF family.

1121335:CST RS04670
gene id: 1121335:CST_RS04670
uniprot id: L7VNE9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1121335:CST RS11345
gene id: 1121335:CST_RS11345
uniprot id: L7VRH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121335:CST RS02020
gene id: 1121335:CST_RS02020
uniprot id: L7VHE2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1121335:CST RS05405
gene id: 1121335:CST_RS05405
uniprot id: L7VNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1121335:CST RS02595
gene id: 1121335:CST_RS02595
uniprot id: L7VM50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1121335:CST RS05620
gene id: 1121335:CST_RS05620
uniprot id: L7VRK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1121335:CST RS10210
gene id: 1121335:CST_RS10210
uniprot id: L7VS35
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS11610
gene id: 1121335:CST_RS11610
uniprot id: L7VMJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1121335:CST RS07945
gene id: 1121335:CST_RS07945
uniprot id: L7VPH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121335:CST RS09925
gene id: 1121335:CST_RS09925
uniprot id: L7VQZ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS05425
gene id: 1121335:CST_RS05425
uniprot id: L7VJC0
names: Similarity
messages: Belongs to the fabD family.

1121335:CST RS11015
gene id: 1121335:CST_RS11015
uniprot id: L7VUP3
names: Similarity
messages: Belongs to the citrate synthase family.

1121335:CST RS02270
gene id: 1121335:CST_RS02270
uniprot id: L7VPK7
names: Similarity
messages: Belongs to the diaminopimelate epimerase family.

1121335:CST RS01720
gene id: 1121335:CST_RS01720
uniprot id: L7VPA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1121335:CST RS06505
gene id: 1121335:CST_RS06505
uniprot id: L7VNL5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1121335:CST RS11585
gene id: 1121335:CST_RS11585
uniprot id: L7VMI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1121335:CST RS09460
gene id: 1121335:CST_RS09460
uniprot id: L7VLD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS10485
gene id: 1121335:CST_RS10485
uniprot id: L7VS69
names: Similarity
messages: Belongs to the CinA family.

1121335:CST RS06740
gene id: 1121335:CST_RS06740
uniprot id: L7VPP2
names: Subunit
messages: Homodimer.

1121335:CST RS07785
gene id: 1121335:CST_RS07785
uniprot id: L7VPF1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1121335:CST RS01435
gene id: 1121335:CST_RS01435
uniprot id: L7VP58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1121335:CST RS07860
gene id: 1121335:CST_RS07860
uniprot id: L7VT10
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1121335:CST RS06780
gene id: 1121335:CST_RS06780
uniprot id: L7VP18
names: Similarity
messages: Belongs to the peptidase A24 family.

1121335:CST RS09845
gene id: 1121335:CST_RS09845
uniprot id: L7VLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1121335:CST RS06750
gene id: 1121335:CST_RS06750
uniprot id: L7VS58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1121335:CST RS02070
gene id: 1121335:CST_RS02070
uniprot id: L7VHF0
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1121335:CST RS10530
gene id: 1121335:CST_RS10530
uniprot id: L7VLY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1121335:CST RS05005
gene id: 1121335:CST_RS05005
uniprot id: L7VNM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1121335:CST RS04825
gene id: 1121335:CST_RS04825
uniprot id: L7VIW7
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS12275
gene id: 1121335:CST_RS12275
uniprot id: L7VMX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1121335:CST RS02415
gene id: 1121335:CST_RS02415
uniprot id: L7VHL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1121335:CST RS03180
gene id: 1121335:CST_RS03180
uniprot id: L7VM48
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1121335:CST RS06205
gene id: 1121335:CST_RS06205
uniprot id: L7VRV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1121335:CST RS02585
gene id: 1121335:CST_RS02585
uniprot id: L7VLQ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1121335:CST RS02340
gene id: 1121335:CST_RS02340
uniprot id: L7VLL0
names: Similarity
messages: Belongs to the peptidase C40 family.

1121335:CST RS10345
gene id: 1121335:CST_RS10345
uniprot id: L7VUC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1121335:CST RS04640
gene id: 1121335:CST_RS04640
uniprot id: L7VIT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1121335:CST RS04335
gene id: 1121335:CST_RS04335
uniprot id: L7VMP0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1121335:CST RS12695
gene id: 1121335:CST_RS12695
uniprot id: L7VN72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS00590
gene id: 1121335:CST_RS00590
uniprot id: L7VKB8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1121335:CST RS12460
gene id: 1121335:CST_RS12460
uniprot id: L7VS60
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1121335:CST RS02120
gene id: 1121335:CST_RS02120
uniprot id: L7VL61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS00265
gene id: 1121335:CST_RS00265
uniprot id: L7VK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS06860
gene id: 1121335:CST_RS06860
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS06755
gene id: 1121335:CST_RS06755
uniprot id: L7VP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1121335:CST RS04775
gene id: 1121335:CST_RS04775
uniprot id: L7VR07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1121335:CST RS04425
gene id: 1121335:CST_RS04425
uniprot id: L7VN90
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1121335:CST RS03095
gene id: 1121335:CST_RS03095
uniprot id: L7VLT8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1121335:CST RS12670
gene id: 1121335:CST_RS12670
uniprot id: L7VN66
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1121335:CST RS07280
gene id: 1121335:CST_RS07280
uniprot id: L7VK71
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1121335:CST RS08965
gene id: 1121335:CST_RS08965
uniprot id: L7VTI5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1121335:CST RS07090
gene id: 1121335:CST_RS07090
uniprot id: L7VPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1121335:CST RS11120
gene id: 1121335:CST_RS11120
uniprot id: L7VM92
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS05965
gene id: 1121335:CST_RS05965
uniprot id: L7VNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1121335:CST RS11615
gene id: 1121335:CST_RS11615
uniprot id: L7VST3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1121335:CST RS06335
gene id: 1121335:CST_RS06335
uniprot id: L7VNI6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1121335:CST RS10120
gene id: 1121335:CST_RS10120
uniprot id: L7VR52
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1121335:CST RS09830
gene id: 1121335:CST_RS09830
uniprot id: L7VQI9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1121335:CST RS11695
gene id: 1121335:CST_RS11695
uniprot id: L7VV41
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS04520
gene id: 1121335:CST_RS04520
uniprot id: L7VNB2
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1121335:CST RS02715
gene id: 1121335:CST_RS02715
uniprot id: M4YKW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1121335:CST RS11175
gene id: 1121335:CST_RS11175
uniprot id: L7VRE0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1121335:CST RS06875
gene id: 1121335:CST_RS06875
uniprot id: L7VJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1121335:CST RS00970
gene id: 1121335:CST_RS00970
uniprot id: L7VGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS06295
gene id: 1121335:CST_RS06295
uniprot id: L7VNS2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1121335:CST RS00380
gene id: 1121335:CST_RS00380
uniprot id: L7VNL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1121335:CST RS07395
gene id: 1121335:CST_RS07395
uniprot id: L7VP47
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1121335:CST RS01330
gene id: 1121335:CST_RS01330
uniprot id: L7VKN4
names: Similarity
messages: Belongs to the UPF0047 family.

1121335:CST RS11680
gene id: 1121335:CST_RS11680
uniprot id: L7VMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1121335:CST RS13020
gene id: 1121335:CST_RS13020
uniprot id: L7VTP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1121335:CST RS03100
gene id: 1121335:CST_RS03100
uniprot id: L7VQ43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS04325
gene id: 1121335:CST_RS04325
uniprot id: L7VN65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS09320
gene id: 1121335:CST_RS09320
uniprot id: L7VLB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1121335:CST RS04715
gene id: 1121335:CST_RS04715
uniprot id: L7VIU6
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS11685
gene id: 1121335:CST_RS11685
uniprot id: L7VSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1121335:CST RS03925
gene id: 1121335:CST_RS03925
uniprot id: L7VMG4
names: Similarity
messages: Belongs to the peptidase C40 family.

1121335:CST RS05600
gene id: 1121335:CST_RS05600
uniprot id: L7VNF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1121335:CST RS08980
gene id: 1121335:CST_RS08980
uniprot id: L7VR60
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1121335:CST RS11350
gene id: 1121335:CST_RS11350
uniprot id: L7VUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121335:CST RS00500
gene id: 1121335:CST_RS00500
uniprot id: L7VNQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1121335:CST RS12050
gene id: 1121335:CST_RS12050
uniprot id: L7VVC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1121335:CST RS10115
gene id: 1121335:CST_RS10115
uniprot id: L7VQR3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1121335:CST RS10175
gene id: 1121335:CST_RS10175
uniprot id: L7VUA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1121335:CST RS04115
gene id: 1121335:CST_RS04115
uniprot id: L7VII7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1121335:CST RS05640
gene id: 1121335:CST_RS05640
uniprot id: L7VN71
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS05465
gene id: 1121335:CST_RS05465
uniprot id: L7VRI4
names: Similarity
messages: Belongs to the class-I fumarase family.

1121335:CST RS04710
gene id: 1121335:CST_RS04710
uniprot id: L7VMW2
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS08520
gene id: 1121335:CST_RS08520
uniprot id: L7VMH4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS11800
gene id: 1121335:CST_RS11800
uniprot id: L7VV64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1121335:CST RS12295
gene id: 1121335:CST_RS12295
uniprot id: L7VSI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1121335:CST RS09545
gene id: 1121335:CST_RS09545
uniprot id: L7VTV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1121335:CST RS05820
gene id: 1121335:CST_RS05820
uniprot id: L7VJH5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1121335:CST RS07970
gene id: 1121335:CST_RS07970
uniprot id: L7VT29
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS11755
gene id: 1121335:CST_RS11755
uniprot id: L7VSV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1121335:CST RS12370
gene id: 1121335:CST_RS12370
uniprot id: L7VSK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1121335:CST RS03695
gene id: 1121335:CST_RS03695
uniprot id: L7VM26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1121335:CST RS10130
gene id: 1121335:CST_RS10130
uniprot id: L7VS22
names: Subcellular Location Annotation
messages: Cell membrane

1121335:CST RS03785
gene id: 1121335:CST_RS03785
uniprot id: L7VME1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS09795
gene id: 1121335:CST_RS09795
uniprot id: L7VQI5
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS00010
gene id: 1121335:CST_RS00010
uniprot id: L7VNB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1121335:CST RS02325
gene id: 1121335:CST_RS02325
uniprot id: L7VLY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1121335:CST RS10195
gene id: 1121335:CST_RS10195
uniprot id: L7VUA5
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS10170
gene id: 1121335:CST_RS10170
uniprot id: L7VQS2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121335:CST RS00085
gene id: 1121335:CST_RS00085
uniprot id: L7VGE8
names: Similarity
messages: Belongs to the UPF0047 family.

1121335:CST RS11135
gene id: 1121335:CST_RS11135
uniprot id: L7VUS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1121335:CST RS01120
gene id: 1121335:CST_RS01120
uniprot id: L7VH03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS08755
gene id: 1121335:CST_RS08755
uniprot id: L7VR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS08110
gene id: 1121335:CST_RS08110
uniprot id: L7VT51
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1121335:CST RS11140
gene id: 1121335:CST_RS11140
uniprot id: L7VRR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1121335:CST RS12245
gene id: 1121335:CST_RS12245
uniprot id: L7VVH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1121335:CST RS06820
gene id: 1121335:CST_RS06820
uniprot id: L7VNS3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS12310
gene id: 1121335:CST_RS12310
uniprot id: L7VS28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1121335:CST RS02830
gene id: 1121335:CST_RS02830
uniprot id: L7VME3
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1121335:CST RS08750
gene id: 1121335:CST_RS08750
uniprot id: L7VL14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS08035
gene id: 1121335:CST_RS08035
uniprot id: L7VPJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1121335:CST RS12020
gene id: 1121335:CST_RS12020
uniprot id: L7VRV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

1121335:CST RS11520
gene id: 1121335:CST_RS11520
uniprot id: L7VMH4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS10235
gene id: 1121335:CST_RS10235
uniprot id: L7VS39
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS00375
gene id: 1121335:CST_RS00375
uniprot id: L7VK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1121335:CST RS10300
gene id: 1121335:CST_RS10300
uniprot id: L7VUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1121335:CST RS05335
gene id: 1121335:CST_RS05335
uniprot id: L7VNX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1121335:CST RS11030
gene id: 1121335:CST_RS11030
uniprot id: L7VSG8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1121335:CST RS02925
gene id: 1121335:CST_RS02925
uniprot id: L7VMG2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1121335:CST RS11085
gene id: 1121335:CST_RS11085
uniprot id: L7VRC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1121335:CST RS06920
gene id: 1121335:CST_RS06920
uniprot id: L7VP50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1121335:CST RS01535
gene id: 1121335:CST_RS01535
uniprot id: L7VL11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1121335:CST RS12595
gene id: 1121335:CST_RS12595
uniprot id: L7VST5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1121335:CST RS02145
gene id: 1121335:CST_RS02145
uniprot id: L7VPI4
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1121335:CST RS05090
gene id: 1121335:CST_RS05090
uniprot id: L7VMW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1121335:CST RS02100
gene id: 1121335:CST_RS02100
uniprot id: L7VPH7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS00440
gene id: 1121335:CST_RS00440
uniprot id: L7VGQ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS09470
gene id: 1121335:CST_RS09470
uniprot id: L7VRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1121335:CST RS03645
gene id: 1121335:CST_RS03645
uniprot id: L7VM16
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1121335:CST RS05800
gene id: 1121335:CST_RS05800
uniprot id: L7VP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS10935
gene id: 1121335:CST_RS10935
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS08050
gene id: 1121335:CST_RS08050
uniprot id: L7VQN7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS08330
gene id: 1121335:CST_RS08330
uniprot id: L7VPY8
names: Subcellular Location Annotation
messages: Cell membrane

1121335:CST RS07020
gene id: 1121335:CST_RS07020
uniprot id: L7VNW5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1121335:CST RS07315
gene id: 1121335:CST_RS07315
uniprot id: L7VQ28
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS02625
gene id: 1121335:CST_RS02625
uniprot id: L7VLK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1121335:CST RS02920
gene id: 1121335:CST_RS02920
uniprot id: L7VI04
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS07950
gene id: 1121335:CST_RS07950
uniprot id: L7VT25
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121335:CST RS06480
gene id: 1121335:CST_RS06480
uniprot id: L7VNL2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1121335:CST RS09655
gene id: 1121335:CST_RS09655
uniprot id: L7VQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusB family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1121335:CST RS12655
gene id: 1121335:CST_RS12655
uniprot id: L7VSC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1121335:CST RS12470
gene id: 1121335:CST_RS12470
uniprot id: L7VSN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1121335:CST RS10365
gene id: 1121335:CST_RS10365
uniprot id: L7VS54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS06070
gene id: 1121335:CST_RS06070
uniprot id: L7VJK4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1121335:CST RS10080
gene id: 1121335:CST_RS10080
uniprot id: L7VLR2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1121335:CST RS00315
gene id: 1121335:CST_RS00315
uniprot id: L7VNJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1121335:CST RS01300
gene id: 1121335:CST_RS01300
uniprot id: L7VKW3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS11510
gene id: 1121335:CST_RS11510
uniprot id: L7VRK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1121335:CST RS07770
gene id: 1121335:CST_RS07770
uniprot id: L7VPP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1121335:CST RS07845
gene id: 1121335:CST_RS07845
uniprot id: L7VKL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1121335:CST RS09400
gene id: 1121335:CST_RS09400
uniprot id: L7VQA0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1121335:CST RS09490
gene id: 1121335:CST_RS09490
uniprot id: L7VLE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1121335:CST RS11335
gene id: 1121335:CST_RS11335
uniprot id: L7VMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121335:CST RS13015
gene id: 1121335:CST_RS13015
uniprot id: L7VNB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1121335:CST RS02535
gene id: 1121335:CST_RS02535
uniprot id: L7VLP9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS08200
gene id: 1121335:CST_RS08200
uniprot id: L7VQQ5
names: Similarity
messages: Belongs to the DtxR/MntR family.

1121335:CST RS07700
gene id: 1121335:CST_RS07700
uniprot id: L7VSW9
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS08230
gene id: 1121335:CST_RS08230
uniprot id: L7VT69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1121335:CST RS04510
gene id: 1121335:CST_RS04510
uniprot id: L7VMS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1121335:CST RS02600
gene id: 1121335:CST_RS02600
uniprot id: L7VLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1121335:CST RS06305
gene id: 1121335:CST_RS06305
uniprot id: L7VPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1121335:CST RS00110
gene id: 1121335:CST_RS00110
uniprot id: L7VGF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1121335:CST RS07960
gene id: 1121335:CST_RS07960
uniprot id: L7VKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS09395
gene id: 1121335:CST_RS09395
uniprot id: L7VRF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1121335:CST RS12480
gene id: 1121335:CST_RS12480
uniprot id: L7VTC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1121335:CST RS05765
gene id: 1121335:CST_RS05765
uniprot id: L7VRN5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1121335:CST RS05035
gene id: 1121335:CST_RS05035
uniprot id: L7VMV5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121335:CST RS06735
gene id: 1121335:CST_RS06735
uniprot id: L7VJW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS03415
gene id: 1121335:CST_RS03415
uniprot id: L7VLY0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1121335:CST RS09300
gene id: 1121335:CST_RS09300
uniprot id: L7VRD0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1121335:CST RS02680
gene id: 1121335:CST_RS02680
uniprot id: L7VPT4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1121335:CST RS05645
gene id: 1121335:CST_RS05645
uniprot id: L7VRL4
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1121335:CST RS01125
gene id: 1121335:CST_RS01125
uniprot id: L7VLB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS05855
gene id: 1121335:CST_RS05855
uniprot id: L7VNA5
names: Similarity
messages: Belongs to the class-I fumarase family.

1121335:CST RS00840
gene id: 1121335:CST_RS00840
uniprot id: L7VL63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1121335:CST RS10385
gene id: 1121335:CST_RS10385
uniprot id: L7VLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1121335:CST RS03035
gene id: 1121335:CST_RS03035
uniprot id: L7VI21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1121335:CST RS01380
gene id: 1121335:CST_RS01380
uniprot id: L7VKP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121335:CST RS05490
gene id: 1121335:CST_RS05490
uniprot id: L7VRI7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS07870
gene id: 1121335:CST_RS07870
uniprot id: L7VKL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1121335:CST RS07475
gene id: 1121335:CST_RS07475
uniprot id: L7VSP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1121335:CST RS04505
gene id: 1121335:CST_RS04505
uniprot id: L7VQV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1121335:CST RS12665
gene id: 1121335:CST_RS12665
uniprot id: L7VSU2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1121335:CST RS10455
gene id: 1121335:CST_RS10455
uniprot id: L7VLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS02320
gene id: 1121335:CST_RS02320
uniprot id: L7VLK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS01360
gene id: 1121335:CST_RS01360
uniprot id: L7VP45
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1121335:CST RS10780
gene id: 1121335:CST_RS10780
uniprot id: L7VSB8
names: Similarity
messages: Belongs to the IspF family.

1121335:CST RS03980
gene id: 1121335:CST_RS03980
uniprot id: L7VMH3
names: Similarity
messages: Belongs to the UxaA family.

1121335:CST RS10745
gene id: 1121335:CST_RS10745
uniprot id: L7VRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0397 family.
messages: Cell membrane

1121335:CST RS10800
gene id: 1121335:CST_RS10800
uniprot id: L7VM27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1121335:CST RS03105
gene id: 1121335:CST_RS03105
uniprot id: L7VM35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS00405
gene id: 1121335:CST_RS00405
uniprot id: L7VNN3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1121335:CST RS01545
gene id: 1121335:CST_RS01545
uniprot id: L7VLI4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1121335:CST RS05365
gene id: 1121335:CST_RS05365
uniprot id: L7VRG3
names: Similarity
messages: Belongs to the citrate synthase family.

1121335:CST RS05395
gene id: 1121335:CST_RS05395
uniprot id: L7VNB8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1121335:CST RS06905
gene id: 1121335:CST_RS06905
uniprot id: L7VPT0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1121335:CST RS06470
gene id: 1121335:CST_RS06470
uniprot id: L7VJR8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS07940
gene id: 1121335:CST_RS07940
uniprot id: L7VQL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1121335:CST RS03410
gene id: 1121335:CST_RS03410
uniprot id: L7VMP7
names: Similarity
messages: Belongs to the DHPS family.

1121335:CST RS11840
gene id: 1121335:CST_RS11840
uniprot id: L7VSY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1121335:CST RS05630
gene id: 1121335:CST_RS05630
uniprot id: L7VJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1121335:CST RS01735
gene id: 1121335:CST_RS01735
uniprot id: L7VLL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS01325
gene id: 1121335:CST_RS01325
uniprot id: L7VLE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1121335:CST RS00025
gene id: 1121335:CST_RS00025
uniprot id: L7VKM5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1121335:CST RS10870
gene id: 1121335:CST_RS10870
uniprot id: L7VRJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1121335:CST RS01625
gene id: 1121335:CST_RS01625
uniprot id: L7VKU6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1121335:CST RS04435
gene id: 1121335:CST_RS04435
uniprot id: L7VQU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1121335:CST RS08240
gene id: 1121335:CST_RS08240
uniprot id: L7VKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121335:CST RS03815
gene id: 1121335:CST_RS03815
uniprot id: L7VID9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1121335:CST RS05085
gene id: 1121335:CST_RS05085
uniprot id: L7VNN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1121335:CST RS03945
gene id: 1121335:CST_RS03945
uniprot id: L7VQJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS06690
gene id: 1121335:CST_RS06690
uniprot id: L7VNP9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1121335:CST RS03065
gene id: 1121335:CST_RS03065
uniprot id: L7VMI8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS11920
gene id: 1121335:CST_RS11920
uniprot id: L7VS82
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1121335:CST RS05440
gene id: 1121335:CST_RS05440
uniprot id: L7VRH8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1121335:CST RS09125
gene id: 1121335:CST_RS09125
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS05605
gene id: 1121335:CST_RS05605
uniprot id: L7VJE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1121335:CST RS03090
gene id: 1121335:CST_RS03090
uniprot id: L7VMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS02465
gene id: 1121335:CST_RS02465
uniprot id: L7VHM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1121335:CST RS11975
gene id: 1121335:CST_RS11975
uniprot id: L7VS89
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1121335:CST RS01175
gene id: 1121335:CST_RS01175
uniprot id: L7VKJ8
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1121335:CST RS01275
gene id: 1121335:CST_RS01275
uniprot id: L7VKV6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1121335:CST RS12175
gene id: 1121335:CST_RS12175
uniprot id: L7VSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1121335:CST RS06935
gene id: 1121335:CST_RS06935
uniprot id: L7VSA2
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1121335:CST RS05270
gene id: 1121335:CST_RS05270
uniprot id: L7VRD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS12215
gene id: 1121335:CST_RS12215
uniprot id: L7VS03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1121335:CST RS09890
gene id: 1121335:CST_RS09890
uniprot id: L7VRV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS01630
gene id: 1121335:CST_RS01630
uniprot id: L7VP93
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1121335:CST RS01560
gene id: 1121335:CST_RS01560
uniprot id: L7VL15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1121335:CST RS13105
gene id: 1121335:CST_RS13105
uniprot id: L7VPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1121335:CST RS09310
gene id: 1121335:CST_RS09310
uniprot id: L7VTQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS06360
gene id: 1121335:CST_RS06360
uniprot id: L7VNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1121335:CST RS12750
gene id: 1121335:CST_RS12750
uniprot id: L7VN77
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1121335:CST RS12385
gene id: 1121335:CST_RS12385
uniprot id: L7VS43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1121335:CST RS02390
gene id: 1121335:CST_RS02390
uniprot id: L7VHL4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1121335:CST RS02945
gene id: 1121335:CST_RS02945
uniprot id: L7VI08
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1121335:CST RS12895
gene id: 1121335:CST_RS12895
uniprot id: L7VVY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS13045
gene id: 1121335:CST_RS13045
uniprot id: L7VTP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1121335:CST RS01020
gene id: 1121335:CST_RS01020
uniprot id: L7VGY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS05435
gene id: 1121335:CST_RS05435
uniprot id: L7VN39
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1121335:CST RS12640
gene id: 1121335:CST_RS12640
uniprot id: L7VST8
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1121335:CST RS10525
gene id: 1121335:CST_RS10525
uniprot id: L7VRC6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1121335:CST RS00125
gene id: 1121335:CST_RS00125
uniprot id: L7VK12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121335:CST RS11320
gene id: 1121335:CST_RS11320
uniprot id: L7VSN1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121335:CST RS00975
gene id: 1121335:CST_RS00975
uniprot id: L7VL85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS08765
gene id: 1121335:CST_RS08765
uniprot id: L7VTE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1121335:CST RS02640
gene id: 1121335:CST_RS02640
uniprot id: L7VHS1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1121335:CST RS11870
gene id: 1121335:CST_RS11870
uniprot id: L7VRT3
names: Similarity
messages: Belongs to the SleB family.

1121335:CST RS01320
gene id: 1121335:CST_RS01320
uniprot id: L7VH34
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1121335:CST RS12615
gene id: 1121335:CST_RS12615
uniprot id: L7VVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1121335:CST RS10720
gene id: 1121335:CST_RS10720
uniprot id: L7VRG5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1121335:CST RS06210
gene id: 1121335:CST_RS06210
uniprot id: L7VNQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1121335:CST RS06990
gene id: 1121335:CST_RS06990
uniprot id: L7VP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1121335:CST RS08065
gene id: 1121335:CST_RS08065
uniprot id: L7VKQ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121335:CST RS07975
gene id: 1121335:CST_RS07975
uniprot id: L7VPT2
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS00880
gene id: 1121335:CST_RS00880
uniprot id: L7VKF1
names: Similarity
messages: Belongs to the hemerythrin family.

1121335:CST RS07920
gene id: 1121335:CST_RS07920
uniprot id: L7VPH3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS02355
gene id: 1121335:CST_RS02355
uniprot id: L7VLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS10400
gene id: 1121335:CST_RS10400
uniprot id: L7VUD5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS04320
gene id: 1121335:CST_RS04320
uniprot id: L7VIM6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1121335:CST RS05250
gene id: 1121335:CST_RS05250
uniprot id: L7VN68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS01285
gene id: 1121335:CST_RS01285
uniprot id: L7VLD5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1121335:CST RS07015
gene id: 1121335:CST_RS07015
uniprot id: L7VPW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1121335:CST RS11835
gene id: 1121335:CST_RS11835
uniprot id: L7VMP1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1121335:CST RS02245
gene id: 1121335:CST_RS02245
uniprot id: L7VPK1
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS10705
gene id: 1121335:CST_RS10705
uniprot id: L7VSA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS01785
gene id: 1121335:CST_RS01785
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS05795
gene id: 1121335:CST_RS05795
uniprot id: L7VJH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS07275
gene id: 1121335:CST_RS07275
uniprot id: L7VPC7
names: Similarity
messages: Belongs to the DprA/Smf family.

1121335:CST RS07120
gene id: 1121335:CST_RS07120
uniprot id: L7VNY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1121335:CST RS04000
gene id: 1121335:CST_RS04000
uniprot id: L7VM80
names: Similarity
messages: Belongs to the UPF0045 family.

1121335:CST RS00705
gene id: 1121335:CST_RS00705
uniprot id: L7VKJ3
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS01375
gene id: 1121335:CST_RS01375
uniprot id: L7VLF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121335:CST RS11905
gene id: 1121335:CST_RS11905
uniprot id: L7VSZ9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1121335:CST RS11355
gene id: 1121335:CST_RS11355
uniprot id: L7VRW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121335:CST RS02550
gene id: 1121335:CST_RS02550
uniprot id: L7VLI1
names: Similarity
messages: Belongs to the UPF0749 family.

1121335:CST RS10505
gene id: 1121335:CST_RS10505
uniprot id: L7VLY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS04560
gene id: 1121335:CST_RS04560
uniprot id: L7VMT5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS09510
gene id: 1121335:CST_RS09510
uniprot id: L7VQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1121335:CST RS01880
gene id: 1121335:CST_RS01880
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS00135
gene id: 1121335:CST_RS00135
uniprot id: L7VK72
names: Similarity
messages: Belongs to the LOR family.

1121335:CST RS08135
gene id: 1121335:CST_RS08135
uniprot id: L7VT55
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121335:CST RS08625
gene id: 1121335:CST_RS08625
uniprot id: L7VTC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1121335:CST RS04750
gene id: 1121335:CST_RS04750
uniprot id: L7VR03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1121335:CST RS04215
gene id: 1121335:CST_RS04215
uniprot id: L7VIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS10295
gene id: 1121335:CST_RS10295
uniprot id: L7VQU3
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1121335:CST RS12425
gene id: 1121335:CST_RS12425
uniprot id: L7VN05
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS02420
gene id: 1121335:CST_RS02420
uniprot id: L7VM06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1121335:CST RS03620
gene id: 1121335:CST_RS03620
uniprot id: L7VM13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1121335:CST RS02115
gene id: 1121335:CST_RS02115
uniprot id: L7VLT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS09335
gene id: 1121335:CST_RS09335
uniprot id: L7VTR3
names: Function
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.

1121335:CST RS07585
gene id: 1121335:CST_RS07585
uniprot id: L7VP89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1121335:CST RS02035
gene id: 1121335:CST_RS02035
uniprot id: L7VL35
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121335:CST RS04455
gene id: 1121335:CST_RS04455
uniprot id: L7VMH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1121335:CST RS00400
gene id: 1121335:CST_RS00400
uniprot id: L7VK88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS12840
gene id: 1121335:CST_RS12840
uniprot id: L7VSF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1121335:CST RS07190
gene id: 1121335:CST_RS07190
uniprot id: L7VQ00
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1121335:CST RS06570
gene id: 1121335:CST_RS06570
uniprot id: L7VNM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1121335:CST RS09710
gene id: 1121335:CST_RS09710
uniprot id: L7VLI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1121335:CST RS10290
gene id: 1121335:CST_RS10290
uniprot id: L7VS45
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1121335:CST RS07160
gene id: 1121335:CST_RS07160
uniprot id: L7VK46
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS00645
gene id: 1121335:CST_RS00645
uniprot id: L7VNS5
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS08100
gene id: 1121335:CST_RS08100
uniprot id: L7VQP1
names: Subcellular Location Annotation
messages: Cell membrane

1121335:CST RS04590
gene id: 1121335:CST_RS04590
uniprot id: L7VIS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS03605
gene id: 1121335:CST_RS03605
uniprot id: L7VMB5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1121335:CST RS04290
gene id: 1121335:CST_RS04290
uniprot id: L7VMM9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1121335:CST RS06545
gene id: 1121335:CST_RS06545
uniprot id: L7VJT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1121335:CST RS11330
gene id: 1121335:CST_RS11330
uniprot id: L7VRW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121335:CST RS05245
gene id: 1121335:CST_RS05245
uniprot id: L7VRB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS08885
gene id: 1121335:CST_RS08885
uniprot id: L7VTG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

1121335:CST RS12550
gene id: 1121335:CST_RS12550
uniprot id: L7VN49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1121335:CST RS01530
gene id: 1121335:CST_RS01530
uniprot id: L7VP77
names: Similarity
messages: Belongs to the MecA family.

1121335:CST RS07480
gene id: 1121335:CST_RS07480
uniprot id: L7VPG8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1121335:CST RS11590
gene id: 1121335:CST_RS11590
uniprot id: L7VSS8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1121335:CST RS10495
gene id: 1121335:CST_RS10495
uniprot id: L7VUF6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1121335:CST RS03995
gene id: 1121335:CST_RS03995
uniprot id: L7VN04
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS06985
gene id: 1121335:CST_RS06985
uniprot id: L7VSB5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1121335:CST RS02695
gene id: 1121335:CST_RS02695
uniprot id: L7VM76
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1121335:CST RS12610
gene id: 1121335:CST_RS12610
uniprot id: L7VSC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1121335:CST RS10560
gene id: 1121335:CST_RS10560
uniprot id: L7VS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS05445
gene id: 1121335:CST_RS05445
uniprot id: L7VNC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1121335:CST RS12405
gene id: 1121335:CST_RS12405
uniprot id: L7VTB1
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS03940
gene id: 1121335:CST_RS03940
uniprot id: L7VM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS02545
gene id: 1121335:CST_RS02545
uniprot id: L7VM38
names: Similarity
messages: Belongs to the UPF0749 family.

1121335:CST RS01230
gene id: 1121335:CST_RS01230
uniprot id: L7VKU9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1121335:CST RS11785
gene id: 1121335:CST_RS11785
uniprot id: L7VS52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS03595
gene id: 1121335:CST_RS03595
uniprot id: L7VM08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS01365
gene id: 1121335:CST_RS01365
uniprot id: L7VKX6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS00945
gene id: 1121335:CST_RS00945
uniprot id: L7VGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS09290
gene id: 1121335:CST_RS09290
uniprot id: L7VQJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS11825
gene id: 1121335:CST_RS11825
uniprot id: L7VV70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1121335:CST RS03050
gene id: 1121335:CST_RS03050
uniprot id: L7VQ35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

1121335:CST RS03165
gene id: 1121335:CST_RS03165
uniprot id: L7VMK5
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS09440
gene id: 1121335:CST_RS09440
uniprot id: L7VLD1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS06590
gene id: 1121335:CST_RS06590
uniprot id: L7VPL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS04380
gene id: 1121335:CST_RS04380
uniprot id: L7VIP0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121335:CST RS08525
gene id: 1121335:CST_RS08525
uniprot id: L7VQX7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS01940
gene id: 1121335:CST_RS01940
uniprot id: L7VPE2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1121335:CST RS09380
gene id: 1121335:CST_RS09380
uniprot id: L7VTS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1121335:CST RS12065
gene id: 1121335:CST_RS12065
uniprot id: L7VT30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1121335:CST RS06745
gene id: 1121335:CST_RS06745
uniprot id: L7VNQ8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1121335:CST RS05040
gene id: 1121335:CST_RS05040
uniprot id: L7VR64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121335:CST RS01440
gene id: 1121335:CST_RS01440
uniprot id: L7VKZ1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1121335:CST RS06960
gene id: 1121335:CST_RS06960
uniprot id: L7VSA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1121335:CST RS05230
gene id: 1121335:CST_RS05230
uniprot id: L7VJ60
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1121335:CST RS09855
gene id: 1121335:CST_RS09855
uniprot id: L7VQJ4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1121335:CST RS04900
gene id: 1121335:CST_RS04900
uniprot id: L7VMS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121335:CST RS03075
gene id: 1121335:CST_RS03075
uniprot id: L7VQ39
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS00225
gene id: 1121335:CST_RS00225
uniprot id: L7VK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1121335:CST RS05350
gene id: 1121335:CST_RS05350
uniprot id: L7VJA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1121335:CST RS09425
gene id: 1121335:CST_RS09425
uniprot id: L7VQA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1121335:CST RS01615
gene id: 1121335:CST_RS01615
uniprot id: L7VH81
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1121335:CST RS05045
gene id: 1121335:CST_RS05045
uniprot id: L7VN26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS04530
gene id: 1121335:CST_RS04530
uniprot id: L7VQW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1121335:CST RS01280
gene id: 1121335:CST_RS01280
uniprot id: L7VH26
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1121335:CST RS09330
gene id: 1121335:CST_RS09330
uniprot id: L7VQ88
names: Similarity
messages: Belongs to the DtxR/MntR family.

1121335:CST RS09920
gene id: 1121335:CST_RS09920
uniprot id: L7VU32
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1121335:CST RS00075
gene id: 1121335:CST_RS00075
uniprot id: L7VNC8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121335:CST RS12935
gene id: 1121335:CST_RS12935
uniprot id: L7VTM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS11305
gene id: 1121335:CST_RS11305
uniprot id: L7VUW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1121335:CST RS06240
gene id: 1121335:CST_RS06240
uniprot id: L7VPD3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1121335:CST RS11765
gene id: 1121335:CST_RS11765
uniprot id: L7VS46
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1121335:CST RS02475
gene id: 1121335:CST_RS02475
uniprot id: L7VLG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1121335:CST RS06405
gene id: 1121335:CST_RS06405
uniprot id: L7VNK0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1121335:CST RS06910
gene id: 1121335:CST_RS06910
uniprot id: L7VNU1
names: Similarity
messages: Belongs to the CapA family.

1121335:CST RS11645
gene id: 1121335:CST_RS11645
uniprot id: L7VRN4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121335:CST RS04395
gene id: 1121335:CST_RS04395
uniprot id: L7VIP5
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS10330
gene id: 1121335:CST_RS10330
uniprot id: L7VLW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1121335:CST RS05780
gene id: 1121335:CST_RS05780
uniprot id: L7VP54
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS05720
gene id: 1121335:CST_RS05720
uniprot id: L7VRM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1121335:CST RS06365
gene id: 1121335:CST_RS06365
uniprot id: L7VRZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1121335:CST RS02725
gene id: 1121335:CST_RS02725
uniprot id: M4Y537
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1121335:CST RS09160
gene id: 1121335:CST_RS09160
uniprot id: L7VTM9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS05120
gene id: 1121335:CST_RS05120
uniprot id: L7VR82
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1121335:CST RS06555
gene id: 1121335:CST_RS06555
uniprot id: L7VNM4
names: Similarity
messages: Belongs to the CapA family.

1121335:CST RS08685
gene id: 1121335:CST_RS08685
uniprot id: L7VR04
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1121335:CST RS07965
gene id: 1121335:CST_RS07965
uniprot id: L7VPI0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1121335:CST RS04555
gene id: 1121335:CST_RS04555
uniprot id: L7VQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1121335:CST RS11595
gene id: 1121335:CST_RS11595
uniprot id: L7VRM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1121335:CST RS04300
gene id: 1121335:CST_RS04300
uniprot id: L7VN56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1121335:CST RS12235
gene id: 1121335:CST_RS12235
uniprot id: L7VT73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1121335:CST RS05790
gene id: 1121335:CST_RS05790
uniprot id: L7VNI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1121335:CST RS04515
gene id: 1121335:CST_RS04515
uniprot id: L7VIR2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121335:CST RS01740
gene id: 1121335:CST_RS01740
uniprot id: L7VKX3
names: Subunit
messages: Homodimer.

1121335:CST RS10060
gene id: 1121335:CST_RS10060
uniprot id: L7VRY5
names: Similarity
messages: Belongs to the UPF0297 family.

1121335:CST RS02995
gene id: 1121335:CST_RS02995
uniprot id: L7VI16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1121335:CST RS01670
gene id: 1121335:CST_RS01670
uniprot id: L7VPA1
names: Similarity
messages: Belongs to the CdaR family.

1121335:CST RS08975
gene id: 1121335:CST_RS08975
uniprot id: L7VL54
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1121335:CST RS01085
gene id: 1121335:CST_RS01085
uniprot id: L7VNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS07325
gene id: 1121335:CST_RS07325
uniprot id: L7VSK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1121335:CST RS11720
gene id: 1121335:CST_RS11720
uniprot id: L7VS37
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1121335:CST RS07935
gene id: 1121335:CST_RS07935
uniprot id: L7VKN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1121335:CST RS09720
gene id: 1121335:CST_RS09720
uniprot id: L7VQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1121335:CST RS08185
gene id: 1121335:CST_RS08185
uniprot id: L7VT63
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS10615
gene id: 1121335:CST_RS10615
uniprot id: L7VR06
names: Similarity
messages: Belongs to the MotB family.

1121335:CST RS10890
gene id: 1121335:CST_RS10890
uniprot id: L7VM45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1121335:CST RS09215
gene id: 1121335:CST_RS09215
uniprot id: L7VL95
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1121335:CST RS00260
gene id: 1121335:CST_RS00260
uniprot id: L7VKT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS11340
gene id: 1121335:CST_RS11340
uniprot id: L7VSN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121335:CST RS10540
gene id: 1121335:CST_RS10540
uniprot id: L7VQZ2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1121335:CST RS05305
gene id: 1121335:CST_RS05305
uniprot id: L7VJ98
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS07755
gene id: 1121335:CST_RS07755
uniprot id: L7VKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS06615
gene id: 1121335:CST_RS06615
uniprot id: L7VPL8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1121335:CST RS09575
gene id: 1121335:CST_RS09575
uniprot id: L7VTW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1121335:CST RS12810
gene id: 1121335:CST_RS12810
uniprot id: L7VTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS03900
gene id: 1121335:CST_RS03900
uniprot id: L7VMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS04245
gene id: 1121335:CST_RS04245
uniprot id: L7VN44
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS10725
gene id: 1121335:CST_RS10725
uniprot id: L7VM15
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1121335:CST RS04755
gene id: 1121335:CST_RS04755
uniprot id: L7VMX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS10475
gene id: 1121335:CST_RS10475
uniprot id: L7VRB6
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS09315
gene id: 1121335:CST_RS09315
uniprot id: L7VQK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121335:CST RS03970
gene id: 1121335:CST_RS03970
uniprot id: L7VM74
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1121335:CST RS11000
gene id: 1121335:CST_RS11000
uniprot id: L7VM68
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS03965
gene id: 1121335:CST_RS03965
uniprot id: L7VMZ9
names: Similarity
messages: Belongs to the aldose epimerase family.

1121335:CST RS11295
gene id: 1121335:CST_RS11295
uniprot id: L7VSM7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1121335:CST RS02865
gene id: 1121335:CST_RS02865
uniprot id: L7VQ01
names: Similarity
messages: Belongs to the GerABKA family.

1121335:CST RS01550
gene id: 1121335:CST_RS01550
uniprot id: L7VKS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1121335:CST RS01290
gene id: 1121335:CST_RS01290
uniprot id: L7VKM3
names: Similarity
messages: Belongs to the CtsR family.

1121335:CST RS03700
gene id: 1121335:CST_RS03700
uniprot id: L7VQF9
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1121335:CST RS05745
gene id: 1121335:CST_RS05745
uniprot id: L7VRM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1121335:CST RS02455
gene id: 1121335:CST_RS02455
uniprot id: L7VPN9
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1121335:CST RS05315
gene id: 1121335:CST_RS05315
uniprot id: L7VN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS04745
gene id: 1121335:CST_RS04745
uniprot id: L7VMN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121335:CST RS08005
gene id: 1121335:CST_RS08005
uniprot id: L7VKP3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1121335:CST RS08710
gene id: 1121335:CST_RS08710
uniprot id: L7VPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1121335:CST RS06970
gene id: 1121335:CST_RS06970
uniprot id: L7VK08
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1121335:CST RS06605
gene id: 1121335:CST_RS06605
uniprot id: L7VNX9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1121335:CST RS08835
gene id: 1121335:CST_RS08835
uniprot id: L7VTF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121335:CST RS02360
gene id: 1121335:CST_RS02360
uniprot id: L7VPM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS01570
gene id: 1121335:CST_RS01570
uniprot id: L7VLI8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1121335:CST RS08045
gene id: 1121335:CST_RS08045
uniprot id: L7VKQ1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

1121335:CST RS10480
gene id: 1121335:CST_RS10480
uniprot id: L7VLY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1121335:CST RS01140
gene id: 1121335:CST_RS01140
uniprot id: L7VKS8
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS12960
gene id: 1121335:CST_RS12960
uniprot id: L7VTN2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS12250
gene id: 1121335:CST_RS12250
uniprot id: L7VMX2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1121335:CST RS11395
gene id: 1121335:CST_RS11395
uniprot id: L7VUY8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1121335:CST RS02315
gene id: 1121335:CST_RS02315
uniprot id: L7VPL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS09230
gene id: 1121335:CST_RS09230
uniprot id: L7VQ66
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1121335:CST RS02915
gene id: 1121335:CST_RS02915
uniprot id: L7VM09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1121335:CST RS09555
gene id: 1121335:CST_RS09555
uniprot id: L7VRK4
names: Similarity
messages: Belongs to the UPF0371 family.

1121335:CST RS09385
gene id: 1121335:CST_RS09385
uniprot id: L7VQL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1121335:CST RS00455
gene id: 1121335:CST_RS00455
uniprot id: L7VNP3
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1121335:CST RS07665
gene id: 1121335:CST_RS07665
uniprot id: L7VQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS13050
gene id: 1121335:CST_RS13050
uniprot id: L7VSJ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1121335:CST RS09515
gene id: 1121335:CST_RS09515
uniprot id: L7VLE6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1121335:CST RS01750
gene id: 1121335:CST_RS01750
uniprot id: L7VL62
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121335:CST RS05700
gene id: 1121335:CST_RS05700
uniprot id: L7VRM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121335:CST RS09850
gene id: 1121335:CST_RS09850
uniprot id: L7VRT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1121335:CST RS03460
gene id: 1121335:CST_RS03460
uniprot id: L7VQB7
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1121335:CST RS04820
gene id: 1121335:CST_RS04820
uniprot id: L7VMY4
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS11690
gene id: 1121335:CST_RS11690
uniprot id: L7VRP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1121335:CST RS10955
gene id: 1121335:CST_RS10955
uniprot id: L7VM58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1121335:CST RS10620
gene id: 1121335:CST_RS10620
uniprot id: L7VUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1121335:CST RS02720
gene id: 1121335:CST_RS02720
uniprot id: M4Y3C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1121335:CST RS01025
gene id: 1121335:CST_RS01025
uniprot id: L7VL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS09635
gene id: 1121335:CST_RS09635
uniprot id: L7VLH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1121335:CST RS07730
gene id: 1121335:CST_RS07730
uniprot id: L7VPN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1121335:CST RS08650
gene id: 1121335:CST_RS08650
uniprot id: L7VQ53
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121335:CST RS01635
gene id: 1121335:CST_RS01635
uniprot id: L7VL32
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1121335:CST RS10310
gene id: 1121335:CST_RS10310
uniprot id: L7VS47
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1121335:CST RS08270
gene id: 1121335:CST_RS08270
uniprot id: L7VQS6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121335:CST RS05055
gene id: 1121335:CST_RS05055
uniprot id: L7VNN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS03575
gene id: 1121335:CST_RS03575
uniprot id: L7VQD5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1121335:CST RS12340
gene id: 1121335:CST_RS12340
uniprot id: L7VVK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1121335:CST RS04100
gene id: 1121335:CST_RS04100
uniprot id: L7VMA0
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS05255
gene id: 1121335:CST_RS05255
uniprot id: L7VJ67
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS03730
gene id: 1121335:CST_RS03730
uniprot id: L7VM31
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1121335:CST RS04525
gene id: 1121335:CST_RS04525
uniprot id: L7VMI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1121335:CST RS04030
gene id: 1121335:CST_RS04030
uniprot id: L7VQK8
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1121335:CST RS06015
gene id: 1121335:CST_RS06015
uniprot id: L7VNM0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1121335:CST RS06385
gene id: 1121335:CST_RS06385
uniprot id: L7VNJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1121335:CST RS07455
gene id: 1121335:CST_RS07455
uniprot id: L7VPG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1121335:CST RS08155
gene id: 1121335:CST_RS08155
uniprot id: L7VQP8
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS10700
gene id: 1121335:CST_RS10700
uniprot id: L7VM12
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1121335:CST RS12110
gene id: 1121335:CST_RS12110
uniprot id: L7VMU1
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1121335:CST RS09725
gene id: 1121335:CST_RS09725
uniprot id: L7VTZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1121335:CST RS05190
gene id: 1121335:CST_RS05190
uniprot id: L7VMZ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1121335:CST RS11165
gene id: 1121335:CST_RS11165
uniprot id: L7VMA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1121335:CST RS11050
gene id: 1121335:CST_RS11050
uniprot id: L7VM78
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1121335:CST RS10875
gene id: 1121335:CST_RS10875
uniprot id: L7VM39
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1121335:CST RS09705
gene id: 1121335:CST_RS09705
uniprot id: L7VQU8
names: Similarity
messages: Belongs to the UPF0473 family.

1121335:CST RS03470
gene id: 1121335:CST_RS03470
uniprot id: L7VM91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1121335:CST RS09520
gene id: 1121335:CST_RS09520
uniprot id: L7VRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121335:CST RS04210
gene id: 1121335:CST_RS04210
uniprot id: L7VML6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS11700
gene id: 1121335:CST_RS11700
uniprot id: L7VS32
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1121335:CST RS03430
gene id: 1121335:CST_RS03430
uniprot id: L7VI73
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS10180
gene id: 1121335:CST_RS10180
uniprot id: L7VR58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1121335:CST RS03670
gene id: 1121335:CST_RS03670
uniprot id: L7VM21
names: Similarity
messages: Belongs to the asp23 family.

1121335:CST RS02810
gene id: 1121335:CST_RS02810
uniprot id: L7VLQ7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121335:CST RS06540
gene id: 1121335:CST_RS06540
uniprot id: L7VNW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS12920
gene id: 1121335:CST_RS12920
uniprot id: L7VVZ0
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1121335:CST RS10960
gene id: 1121335:CST_RS10960
uniprot id: L7VSF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1121335:CST RS00870
gene id: 1121335:CST_RS00870
uniprot id: L7VKM7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1121335:CST RS09450
gene id: 1121335:CST_RS09450
uniprot id: L7VQB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1121335:CST RS07320
gene id: 1121335:CST_RS07320
uniprot id: L7VP30
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1121335:CST RS12415
gene id: 1121335:CST_RS12415
uniprot id: L7VVM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS04985
gene id: 1121335:CST_RS04985
uniprot id: L7VMU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1121335:CST RS09935
gene id: 1121335:CST_RS09935
uniprot id: L7VRW2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1121335:CST RS07045
gene id: 1121335:CST_RS07045
uniprot id: L7VNX1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1121335:CST RS11465
gene id: 1121335:CST_RS11465
uniprot id: L7VV02
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1121335:CST RS03855
gene id: 1121335:CST_RS03855
uniprot id: L7VIE3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CarB family.
messages: Belongs to the diaminopimelate epimerase family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS01340
gene id: 1121335:CST_RS01340
uniprot id: L7VKX1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1121335:CST RS11370
gene id: 1121335:CST_RS11370
uniprot id: L7VRH9
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS09535
gene id: 1121335:CST_RS09535
uniprot id: L7VLE9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

1121335:CST RS02670
gene id: 1121335:CST_RS02670
uniprot id: L7VM71
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1121335:CST RS10205
gene id: 1121335:CST_RS10205
uniprot id: L7VLU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1121335:CST RS01045
gene id: 1121335:CST_RS01045
uniprot id: L7VGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS09650
gene id: 1121335:CST_RS09650
uniprot id: L7VTX6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1121335:CST RS08630
gene id: 1121335:CST_RS08630
uniprot id: L7VQ48
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1121335:CST RS06980
gene id: 1121335:CST_RS06980
uniprot id: L7VNV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1121335:CST RS12345
gene id: 1121335:CST_RS12345
uniprot id: L7VSK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1121335:CST RS07290
gene id: 1121335:CST_RS07290
uniprot id: L7VP26
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1121335:CST RS00910
gene id: 1121335:CST_RS00910
uniprot id: L7VKN6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121335:CST RS04675
gene id: 1121335:CST_RS04675
uniprot id: L7VML7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1121335:CST RS09240
gene id: 1121335:CST_RS09240
uniprot id: L7VQI6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1121335:CST RS01350
gene id: 1121335:CST_RS01350
uniprot id: L7VLE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1121335:CST RS09340
gene id: 1121335:CST_RS09340
uniprot id: L7VQK7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1121335:CST RS05955
gene id: 1121335:CST_RS05955
uniprot id: L7VNB7
names: Similarity
messages: Belongs to the GSP E family.

1121335:CST RS06060
gene id: 1121335:CST_RS06060
uniprot id: L7VRT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1121335:CST RS05235
gene id: 1121335:CST_RS05235
uniprot id: L7VNS7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1121335:CST RS06125
gene id: 1121335:CST_RS06125
uniprot id: L7VPB2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1121335:CST RS02435
gene id: 1121335:CST_RS02435
uniprot id: L7VLN0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS00300
gene id: 1121335:CST_RS00300
uniprot id: L7VGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS04310
gene id: 1121335:CST_RS04310
uniprot id: L7VQR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1121335:CST RS12230
gene id: 1121335:CST_RS12230
uniprot id: L7VMW6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1121335:CST RS09610
gene id: 1121335:CST_RS09610
uniprot id: L7VLG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1121335:CST RS03140
gene id: 1121335:CST_RS03140
uniprot id: L7VMK0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1121335:CST RS03135
gene id: 1121335:CST_RS03135
uniprot id: L7VI34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1121335:CST RS10555
gene id: 1121335:CST_RS10555
uniprot id: L7VLZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS08615
gene id: 1121335:CST_RS08615
uniprot id: L7VQZ1
names: Similarity
messages: Belongs to the ThiD family.

1121335:CST RS09525
gene id: 1121335:CST_RS09525
uniprot id: L7VQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1121335:CST RS02880
gene id: 1121335:CST_RS02880
uniprot id: L7VMF2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1121335:CST RS00875
gene id: 1121335:CST_RS00875
uniprot id: L7VL70
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS08145
gene id: 1121335:CST_RS08145
uniprot id: L7VKR6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1121335:CST RS05265
gene id: 1121335:CST_RS05265
uniprot id: L7VN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS10260
gene id: 1121335:CST_RS10260
uniprot id: L7VS42
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1121335:CST RS10075
gene id: 1121335:CST_RS10075
uniprot id: L7VR30
names: Similarity
messages: Belongs to the GerABKA family.

1121335:CST RS07035
gene id: 1121335:CST_RS07035
uniprot id: L7VK21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1121335:CST RS01610
gene id: 1121335:CST_RS01610
uniprot id: L7VL26
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1121335:CST RS05690
gene id: 1121335:CST_RS05690
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS11895
gene id: 1121335:CST_RS11895
uniprot id: L7VS75
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1121335:CST RS02770
gene id: 1121335:CST_RS02770
uniprot id: L7VM97
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1121335:CST RS06705
gene id: 1121335:CST_RS06705
uniprot id: L7VJV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1121335:CST RS03205
gene id: 1121335:CST_RS03205
uniprot id: L7VI45
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS08390
gene id: 1121335:CST_RS08390
uniprot id: L7VKV4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1121335:CST RS08025
gene id: 1121335:CST_RS08025
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS06115
gene id: 1121335:CST_RS06115
uniprot id: L7VNN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121335:CST RS04905
gene id: 1121335:CST_RS04905
uniprot id: L7VR36
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1121335:CST RS06885
gene id: 1121335:CST_RS06885
uniprot id: L7VNT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1121335:CST RS09435
gene id: 1121335:CST_RS09435
uniprot id: L7VQN5
names: Similarity
messages: Belongs to the TrpC family.

1121335:CST RS12465
gene id: 1121335:CST_RS12465
uniprot id: L7VVM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1121335:CST RS04580
gene id: 1121335:CST_RS04580
uniprot id: L7VQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

1121335:CST RS04410
gene id: 1121335:CST_RS04410
uniprot id: L7VQT7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1121335:CST RS05415
gene id: 1121335:CST_RS05415
uniprot id: L7VRH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1121335:CST RS12060
gene id: 1121335:CST_RS12060
uniprot id: L7VMT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1121335:CST RS11780
gene id: 1121335:CST_RS11780
uniprot id: L7VV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS09455
gene id: 1121335:CST_RS09455
uniprot id: L7VQP0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1121335:CST RS09885
gene id: 1121335:CST_RS09885
uniprot id: L7VLL7
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1121335:CST RS07345
gene id: 1121335:CST_RS07345
uniprot id: L7VP36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

1121335:CST RS07210
gene id: 1121335:CST_RS07210
uniprot id: L7VQ05
names: Similarity
messages: Belongs to the peptidase U62 family.

1121335:CST RS07365
gene id: 1121335:CST_RS07365
uniprot id: L7VQ42
names: Similarity
messages: Belongs to the hemerythrin family.

1121335:CST RS08675
gene id: 1121335:CST_RS08675
uniprot id: L7VQ57
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS12075
gene id: 1121335:CST_RS12075
uniprot id: L7VVC8
names: Similarity
messages: Belongs to the bacterial flagellin family.

1121335:CST RS04650
gene id: 1121335:CST_RS04650
uniprot id: L7VML2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1121335:CST RS12835
gene id: 1121335:CST_RS12835
uniprot id: L7VTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1121335:CST RS07205
gene id: 1121335:CST_RS07205
uniprot id: L7VK57
names: Similarity
messages: Belongs to the peptidase U62 family.

1121335:CST RS04870
gene id: 1121335:CST_RS04870
uniprot id: L7VNJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS04260
gene id: 1121335:CST_RS04260
uniprot id: L7VMM5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS09480
gene id: 1121335:CST_RS09480
uniprot id: L7VTU2
names: Similarity
messages: Belongs to the YicC/YloC family.

1121335:CST RS05895
gene id: 1121335:CST_RS05895
uniprot id: L7VJI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1121335:CST RS12305
gene id: 1121335:CST_RS12305
uniprot id: L7VT91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1121335:CST RS01215
gene id: 1121335:CST_RS01215
uniprot id: L7VH15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1121335:CST RS06345
gene id: 1121335:CST_RS06345
uniprot id: L7VNT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1121335:CST RS02310
gene id: 1121335:CST_RS02310
uniprot id: L7VLB3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS05610
gene id: 1121335:CST_RS05610
uniprot id: L7VP25
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS00575
gene id: 1121335:CST_RS00575
uniprot id: L7VKH2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1121335:CST RS11195
gene id: 1121335:CST_RS11195
uniprot id: L7VUU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS00775
gene id: 1121335:CST_RS00775
uniprot id: L7VKD9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1121335:CST RS08255
gene id: 1121335:CST_RS08255
uniprot id: L7VT72
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS06560
gene id: 1121335:CST_RS06560
uniprot id: L7VS24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1121335:CST RS07775
gene id: 1121335:CST_RS07775
uniprot id: L7VKK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1121335:CST RS11725
gene id: 1121335:CST_RS11725
uniprot id: L7VML5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1121335:CST RS00845
gene id: 1121335:CST_RS00845
uniprot id: L7VKE7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1121335:CST RS03520
gene id: 1121335:CST_RS03520
uniprot id: L7VLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS06375
gene id: 1121335:CST_RS06375
uniprot id: L7VJQ0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1121335:CST RS06520
gene id: 1121335:CST_RS06520
uniprot id: L7VJS6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS09560
gene id: 1121335:CST_RS09560
uniprot id: L7VTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1121335:CST RS11745
gene id: 1121335:CST_RS11745
uniprot id: L7VS41
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1121335:CST RS13770
gene id: 1121335:CST_RS13770
uniprot id: L7VVA1
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS09730
gene id: 1121335:CST_RS09730
uniprot id: L7VQV2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1121335:CST RS03085
gene id: 1121335:CST_RS03085
uniprot id: L7VI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS11470
gene id: 1121335:CST_RS11470
uniprot id: L7VRY8
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1121335:CST RS03315
gene id: 1121335:CST_RS03315
uniprot id: L7VLW6
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS03505
gene id: 1121335:CST_RS03505
uniprot id: L7VM99
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1121335:CST RS03330
gene id: 1121335:CST_RS03330
uniprot id: L7VMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1121335:CST RS08260
gene id: 1121335:CST_RS08260
uniprot id: L7VPX5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS09680
gene id: 1121335:CST_RS09680
uniprot id: L7VQU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1121335:CST RS00860
gene id: 1121335:CST_RS00860
uniprot id: L7VKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121335:CST RS02180
gene id: 1121335:CST_RS02180
uniprot id: L7VHH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS00695
gene id: 1121335:CST_RS00695
uniprot id: L7VKD0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS12300
gene id: 1121335:CST_RS12300
uniprot id: L7VMY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1121335:CST RS09945
gene id: 1121335:CST_RS09945
uniprot id: L7VU38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS07660
gene id: 1121335:CST_RS07660
uniprot id: L7VKE8
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS06510
gene id: 1121335:CST_RS06510
uniprot id: L7VS15
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1121335:CST RS09690
gene id: 1121335:CST_RS09690
uniprot id: L7VRP7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1121335:CST RS01515
gene id: 1121335:CST_RS01515
uniprot id: L7VH66
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1121335:CST RS10670
gene id: 1121335:CST_RS10670
uniprot id: L7VUH9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1121335:CST RS01420
gene id: 1121335:CST_RS01420
uniprot id: L7VH49
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS02705
gene id: 1121335:CST_RS02705
uniprot id: L7VPU1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS07890
gene id: 1121335:CST_RS07890
uniprot id: L7VPR4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1121335:CST RS04120
gene id: 1121335:CST_RS04120
uniprot id: L7VN23
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1121335:CST RS04385
gene id: 1121335:CST_RS04385
uniprot id: L7VQT2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1121335:CST RS12790
gene id: 1121335:CST_RS12790
uniprot id: L7VVW7
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS07895
gene id: 1121335:CST_RS07895
uniprot id: L7VQJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1121335:CST RS07505
gene id: 1121335:CST_RS07505
uniprot id: L7VPH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS01640
gene id: 1121335:CST_RS01640
uniprot id: L7VLK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1121335:CST RS03325
gene id: 1121335:CST_RS03325
uniprot id: L7VI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121335:CST RS06665
gene id: 1121335:CST_RS06665
uniprot id: L7VNP6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1121335:CST RS08935
gene id: 1121335:CST_RS08935
uniprot id: L7VL46
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121335:CST RS01620
gene id: 1121335:CST_RS01620
uniprot id: L7VLJ8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1121335:CST RS00765
gene id: 1121335:CST_RS00765
uniprot id: L7VGV1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS06095
gene id: 1121335:CST_RS06095
uniprot id: L7VP54
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS11655
gene id: 1121335:CST_RS11655
uniprot id: L7VS19
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1121335:CST RS03170
gene id: 1121335:CST_RS03170
uniprot id: L7VLU8
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1121335:CST RS04445
gene id: 1121335:CST_RS04445
uniprot id: L7VIQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1121335:CST RS10200
gene id: 1121335:CST_RS10200
uniprot id: L7VR63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1121335:CST RS05420
gene id: 1121335:CST_RS05420
uniprot id: L7VNC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1121335:CST RS12160
gene id: 1121335:CST_RS12160
uniprot id: L7VT56
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1121335:CST RS09715
gene id: 1121335:CST_RS09715
uniprot id: L7VRQ2
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

1121335:CST RS08585
gene id: 1121335:CST_RS08585
uniprot id: L7VQ38
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1121335:CST RS09140
gene id: 1121335:CST_RS09140
uniprot id: L7VR98
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1121335:CST RS01315
gene id: 1121335:CST_RS01315
uniprot id: L7VKM9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1121335:CST RS12730
gene id: 1121335:CST_RS12730
uniprot id: L7VTJ5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1121335:CST RS12290
gene id: 1121335:CST_RS12290
uniprot id: L7VVI8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1121335:CST RS05375
gene id: 1121335:CST_RS05375
uniprot id: L7VJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1121335:CST RS05755
gene id: 1121335:CST_RS05755
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS07795
gene id: 1121335:CST_RS07795
uniprot id: L7VPP8
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1121335:CST RS00305
gene id: 1121335:CST_RS00305
uniprot id: L7VKU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS03825
gene id: 1121335:CST_RS03825
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS12775
gene id: 1121335:CST_RS12775
uniprot id: L7VN81
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1121335:CST RS09500
gene id: 1121335:CST_RS09500
uniprot id: L7VQB9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1121335:CST RS10055
gene id: 1121335:CST_RS10055
uniprot id: L7VLP4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1121335:CST RS00055
gene id: 1121335:CST_RS00055
uniprot id: L7VKN3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS07390
gene id: 1121335:CST_RS07390
uniprot id: L7VQ47
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS00785
gene id: 1121335:CST_RS00785
uniprot id: L7VKK6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1121335:CST RS09280
gene id: 1121335:CST_RS09280
uniprot id: L7VQ76
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1121335:CST RS04490
gene id: 1121335:CST_RS04490
uniprot id: L7VIQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS12095
gene id: 1121335:CST_RS12095
uniprot id: L7VRX7
names: Similarity
messages: Belongs to the FlgM family.

1121335:CST RS03710
gene id: 1121335:CST_RS03710
uniprot id: L7VIC2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1121335:CST RS06855
gene id: 1121335:CST_RS06855
uniprot id: L7VS85
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1121335:CST RS05675
gene id: 1121335:CST_RS05675
uniprot id: L7VNG3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1121335:CST RS09370
gene id: 1121335:CST_RS09370
uniprot id: L7VRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1121335:CST RS01680
gene id: 1121335:CST_RS01680
uniprot id: L7VH94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1121335:CST RS12185
gene id: 1121335:CST_RS12185
uniprot id: L7VT62
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1121335:CST RS07525
gene id: 1121335:CST_RS07525
uniprot id: L7VSQ4
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS04635
gene id: 1121335:CST_RS04635
uniprot id: L7VMU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1121335:CST RS12335
gene id: 1121335:CST_RS12335
uniprot id: L7VS34
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1121335:CST RS05215
gene id: 1121335:CST_RS05215
uniprot id: L7VMZ6
names: Similarity
messages: Belongs to the UPF0111 family.

1121335:CST RS12965
gene id: 1121335:CST_RS12965
uniprot id: L7VSI0
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS01705
gene id: 1121335:CST_RS01705
uniprot id: L7VH96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1121335:CST RS10515
gene id: 1121335:CST_RS10515
uniprot id: L7VQY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1121335:CST RS00410
gene id: 1121335:CST_RS00410
uniprot id: L7VKF2
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1121335:CST RS07625
gene id: 1121335:CST_RS07625
uniprot id: L7VST1
names: Similarity
messages: Belongs to the ribulokinase family.

1121335:CST RS09950
gene id: 1121335:CST_RS09950
uniprot id: L7VQZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1121335:CST RS09505
gene id: 1121335:CST_RS09505
uniprot id: L7VTU6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1121335:CST RS12125
gene id: 1121335:CST_RS12125
uniprot id: L7VVE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1121335:CST RS04495
gene id: 1121335:CST_RS04495
uniprot id: L7VNA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS09035
gene id: 1121335:CST_RS09035
uniprot id: L7VQD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

1121335:CST RS00745
gene id: 1121335:CST_RS00745
uniprot id: L7VL47
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1121335:CST RS06435
gene id: 1121335:CST_RS06435
uniprot id: L7VS02
names: Similarity
messages: Belongs to the GSP E family.

1121335:CST RS08970
gene id: 1121335:CST_RS08970
uniprot id: L7VQC4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1121335:CST RS00950
gene id: 1121335:CST_RS00950
uniprot id: L7VL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS12355
gene id: 1121335:CST_RS12355
uniprot id: L7VTA2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1121335:CST RS07535
gene id: 1121335:CST_RS07535
uniprot id: L7VKB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1121335:CST RS08985
gene id: 1121335:CST_RS08985
uniprot id: L7VQ14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS11990
gene id: 1121335:CST_RS11990
uniprot id: L7VRV3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1121335:CST RS04995
gene id: 1121335:CST_RS04995
uniprot id: L7VN18
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

1121335:CST RS06465
gene id: 1121335:CST_RS06465
uniprot id: L7VNV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1121335:CST RS11205
gene id: 1121335:CST_RS11205
uniprot id: L7VSK5
names: Similarity
messages: Belongs to the UPF0758 family.

1121335:CST RS00145
gene id: 1121335:CST_RS00145
uniprot id: L7VKQ3
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS12520
gene id: 1121335:CST_RS12520
uniprot id: L7VSS3
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

1121335:CST RS05585
gene id: 1121335:CST_RS05585
uniprot id: L7VP20
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS08215
gene id: 1121335:CST_RS08215
uniprot id: L7VPW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1121335:CST RS10730
gene id: 1121335:CST_RS10730
uniprot id: L7VSA6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1121335:CST RS00360
gene id: 1121335:CST_RS00360
uniprot id: L7VKC6
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS08020
gene id: 1121335:CST_RS08020
uniprot id: L7VKP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1121335:CST RS02775
gene id: 1121335:CST_RS02775
uniprot id: L7VLN9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1121335:CST RS08870
gene id: 1121335:CST_RS08870
uniprot id: L7VQ91
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1121335:CST RS10490
gene id: 1121335:CST_RS10490
uniprot id: L7VQX8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1121335:CST RS06130
gene id: 1121335:CST_RS06130
uniprot id: L7VNE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS07070
gene id: 1121335:CST_RS07070
uniprot id: L7VNX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1121335:CST RS07060
gene id: 1121335:CST_RS07060
uniprot id: L7VK26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

1121335:CST RS10885
gene id: 1121335:CST_RS10885
uniprot id: L7VRK2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1121335:CST RS04005
gene id: 1121335:CST_RS04005
uniprot id: L7VQK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS08375
gene id: 1121335:CST_RS08375
uniprot id: L7VPN8
names: Similarity
messages: Belongs to the glutamate synthase family.

1121335:CST RS05205
gene id: 1121335:CST_RS05205
uniprot id: L7VJ55
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121335:CST RS09420
gene id: 1121335:CST_RS09420
uniprot id: L7VRF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1121335:CST RS07360
gene id: 1121335:CST_RS07360
uniprot id: L7VK82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1121335:CST RS12070
gene id: 1121335:CST_RS12070
uniprot id: L7VRX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1121335:CST RS09895
gene id: 1121335:CST_RS09895
uniprot id: L7VQK5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1121335:CST RS13810
gene id: 1121335:CST_RS13810
uniprot id: L7VNB1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1121335:CST RS04140
gene id: 1121335:CST_RS04140
uniprot id: L7VIJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1121335:CST RS08345
gene id: 1121335:CST_RS08345
uniprot id: L7VPN5
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS10165
gene id: 1121335:CST_RS10165
uniprot id: L7VS26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1121335:CST RS12220
gene id: 1121335:CST_RS12220
uniprot id: L7VVH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1121335:CST RS03655
gene id: 1121335:CST_RS03655
uniprot id: L7VMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1121335:CST RS07565
gene id: 1121335:CST_RS07565
uniprot id: L7VP84
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1121335:CST RS07300
gene id: 1121335:CST_RS07300
uniprot id: L7VPD2
names: Similarity
messages: Belongs to the GerABKA family.

1121335:CST RS10535
gene id: 1121335:CST_RS10535
uniprot id: L7VS77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1121335:CST RS11390
gene id: 1121335:CST_RS11390
uniprot id: L7VSP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1121335:CST RS07295
gene id: 1121335:CST_RS07295
uniprot id: L7VSK1
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1121335:CST RS04545
gene id: 1121335:CST_RS04545
uniprot id: L7VNB9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1121335:CST RS08775
gene id: 1121335:CST_RS08775
uniprot id: L7VL18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1121335:CST RS03985
gene id: 1121335:CST_RS03985
uniprot id: L7VIG5
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

1121335:CST RS11200
gene id: 1121335:CST_RS11200
uniprot id: L7VMA9
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1121335:CST RS04725
gene id: 1121335:CST_RS04725
uniprot id: L7VMM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1121335:CST RS12380
gene id: 1121335:CST_RS12380
uniprot id: L7VTA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1121335:CST RS04110
gene id: 1121335:CST_RS04110
uniprot id: L7VMJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1121335:CST RS06655
gene id: 1121335:CST_RS06655
uniprot id: L7VJV1
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

1121335:CST RS03435
gene id: 1121335:CST_RS03435
uniprot id: L7VMQ1
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS10225
gene id: 1121335:CST_RS10225
uniprot id: L7VR68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1121335:CST RS06135
gene id: 1121335:CST_RS06135
uniprot id: L7VRU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121335:CST RS11230
gene id: 1121335:CST_RS11230
uniprot id: L7VSL1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1121335:CST RS06660
gene id: 1121335:CST_RS06660
uniprot id: L7VPM6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121335:CST RS10920
gene id: 1121335:CST_RS10920
uniprot id: L7VR84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1121335:CST RS06530
gene id: 1121335:CST_RS06530
uniprot id: L7VNL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS05635
gene id: 1121335:CST_RS05635
uniprot id: L7VP29
names: Similarity
messages: Belongs to the thioredoxin family.

1121335:CST RS10910
gene id: 1121335:CST_RS10910
uniprot id: L7VM49
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1121335:CST RS06110
gene id: 1121335:CST_RS06110
uniprot id: L7VRT9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS08340
gene id: 1121335:CST_RS08340
uniprot id: L7VQT8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS01310
gene id: 1121335:CST_RS01310
uniprot id: L7VLE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1121335:CST RS02990
gene id: 1121335:CST_RS02990
uniprot id: L7VM20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1121335:CST RS10740
gene id: 1121335:CST_RS10740
uniprot id: L7VUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1121335:CST RS12330
gene id: 1121335:CST_RS12330
uniprot id: L7VT96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1121335:CST RS09475
gene id: 1121335:CST_RS09475
uniprot id: L7VQB6
names: Similarity
messages: Belongs to the RemA family.

1121335:CST RS02520
gene id: 1121335:CST_RS02520
uniprot id: L7VM30
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1121335:CST RS04805
gene id: 1121335:CST_RS04805
uniprot id: L7VIW4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121335:CST RS10940
gene id: 1121335:CST_RS10940
uniprot id: L7VR89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1121335:CST RS12510
gene id: 1121335:CST_RS12510
uniprot id: L7VSA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS13765
gene id: 1121335:CST_RS13765
uniprot id: L7VRU8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1121335:CST RS07340
gene id: 1121335:CST_RS07340
uniprot id: L7VQ36
names: Similarity
messages: Belongs to the sigma-70 factor family.

1121335:CST RS11080
gene id: 1121335:CST_RS11080
uniprot id: L7VSH6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1121335:CST RS02630
gene id: 1121335:CST_RS02630
uniprot id: L7VPS4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1121335:CST RS00485
gene id: 1121335:CST_RS00485
uniprot id: L7VKF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1121335:CST RS07905
gene id: 1121335:CST_RS07905
uniprot id: L7VPR9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1121335:CST RS00080
gene id: 1121335:CST_RS00080
uniprot id: L7VK62
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1121335:CST RS06080
gene id: 1121335:CST_RS06080
uniprot id: L7VND7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1121335:CST RS12280
gene id: 1121335:CST_RS12280
uniprot id: L7VT85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1121335:CST RS05400
gene id: 1121335:CST_RS05400
uniprot id: L7VJB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1121335:CST RS06525
gene id: 1121335:CST_RS06525
uniprot id: L7VPJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1121335:CST RS12360
gene id: 1121335:CST_RS12360
uniprot id: L7VS38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1121335:CST RS10395
gene id: 1121335:CST_RS10395
uniprot id: L7VQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1121335:CST RS07135
gene id: 1121335:CST_RS07135
uniprot id: L7VK42
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

1121335:CST RS07760
gene id: 1121335:CST_RS07760
uniprot id: L7VQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS02860
gene id: 1121335:CST_RS02860
uniprot id: L7VLR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1121335:CST RS11215
gene id: 1121335:CST_RS11215
uniprot id: L7VUU6
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS09180
gene id: 1121335:CST_RS09180
uniprot id: L7VTN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS11515
gene id: 1121335:CST_RS11515
uniprot id: L7VV10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS04175
gene id: 1121335:CST_RS04175
uniprot id: L7VMB2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1121335:CST RS08440
gene id: 1121335:CST_RS08440
uniprot id: L7VQV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS04875
gene id: 1121335:CST_RS04875
uniprot id: L7VMR5
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS12080
gene id: 1121335:CST_RS12080
uniprot id: L7VSB9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1121335:CST RS05020
gene id: 1121335:CST_RS05020
uniprot id: L7VN22
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1121335:CST RS05180
gene id: 1121335:CST_RS05180
uniprot id: L7VNR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1121335:CST RS10305
gene id: 1121335:CST_RS10305
uniprot id: L7VR83
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1121335:CST RS05615
gene id: 1121335:CST_RS05615
uniprot id: L7VN67
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1121335:CST RS10500
gene id: 1121335:CST_RS10500
uniprot id: L7VRC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1121335:CST RS06955
gene id: 1121335:CST_RS06955
uniprot id: L7VNV0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1121335:CST RS08660
gene id: 1121335:CST_RS08660
uniprot id: L7VR00
names: Similarity
messages: Belongs to the ArsC family.

1121335:CST RS06965
gene id: 1121335:CST_RS06965
uniprot id: L7VP60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1121335:CST RS06355
gene id: 1121335:CST_RS06355
uniprot id: L7VPF8
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1121335:CST RS07635
gene id: 1121335:CST_RS07635
uniprot id: L7VKE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1121335:CST RS04105
gene id: 1121335:CST_RS04105
uniprot id: L7VQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1121335:CST RS11600
gene id: 1121335:CST_RS11600
uniprot id: L7VV24
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1121335:CST RS09760
gene id: 1121335:CST_RS09760
uniprot id: L7VLJ4
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS11045
gene id: 1121335:CST_RS11045
uniprot id: L7VRP3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS09590
gene id: 1121335:CST_RS09590
uniprot id: L7VRM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1121335:CST RS02745
gene id: 1121335:CST_RS02745
uniprot id: L7VM90
names: Similarity
messages: Belongs to the TelA family.

1121335:CST RS12375
gene id: 1121335:CST_RS12375
uniprot id: L7VMZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1121335:CST RS07685
gene id: 1121335:CST_RS07685
uniprot id: L7VKF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1121335:CST RS11650
gene id: 1121335:CST_RS11650
uniprot id: L7VV32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121335:CST RS11480
gene id: 1121335:CST_RS11480
uniprot id: L7VSR1
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS10190
gene id: 1121335:CST_RS10190
uniprot id: L7VS30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS07530
gene id: 1121335:CST_RS07530
uniprot id: L7VPH8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1121335:CST RS04470
gene id: 1121335:CST_RS04470
uniprot id: L7VN99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1121335:CST RS08920
gene id: 1121335:CST_RS08920
uniprot id: L7VPZ8
names: Similarity
messages: Belongs to the peptidase S66 family.

1121335:CST RS00545
gene id: 1121335:CST_RS00545
uniprot id: L7VKB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS04250
gene id: 1121335:CST_RS04250
uniprot id: L7VMC5
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS10710
gene id: 1121335:CST_RS10710
uniprot id: L7VR33
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1121335:CST RS05825
gene id: 1121335:CST_RS05825
uniprot id: L7VP62
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1121335:CST RS06695
gene id: 1121335:CST_RS06695
uniprot id: L7VS49
names: Similarity
messages: Belongs to the threonine synthase family.

1121335:CST RS01415
gene id: 1121335:CST_RS01415
uniprot id: L7VKY5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1121335:CST RS10640
gene id: 1121335:CST_RS10640
uniprot id: L7VR11
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1121335:CST RS03955
gene id: 1121335:CST_RS03955
uniprot id: L7VIG1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS08175
gene id: 1121335:CST_RS08175
uniprot id: L7VQQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121335:CST RS03880
gene id: 1121335:CST_RS03880
uniprot id: L7VIE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1121335:CST RS09550
gene id: 1121335:CST_RS09550
uniprot id: L7VQQ8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1121335:CST RS00015
gene id: 1121335:CST_RS00015
uniprot id: L7VK51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1121335:CST RS12255
gene id: 1121335:CST_RS12255
uniprot id: L7VT79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1121335:CST RS10980
gene id: 1121335:CST_RS10980
uniprot id: L7VSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS10460
gene id: 1121335:CST_RS10460
uniprot id: L7VS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS07470
gene id: 1121335:CST_RS07470
uniprot id: L7VP65
names: Similarity
messages: Belongs to the YggT family.

1121335:CST RS08840
gene id: 1121335:CST_RS08840
uniprot id: L7VQ86
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS04720
gene id: 1121335:CST_RS04720
uniprot id: L7VNG0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1121335:CST RS01135
gene id: 1121335:CST_RS01135
uniprot id: L7VP00
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1121335:CST RS09570
gene id: 1121335:CST_RS09570
uniprot id: L7VRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1121335:CST RS06065
gene id: 1121335:CST_RS06065
uniprot id: L7VNM7
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1121335:CST RS05580
gene id: 1121335:CST_RS05580
uniprot id: L7VJD9
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS06675
gene id: 1121335:CST_RS06675
uniprot id: L7VNZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1121335:CST RS06625
gene id: 1121335:CST_RS06625
uniprot id: L7VNY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1121335:CST RS06195
gene id: 1121335:CST_RS06195
uniprot id: L7VPC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1121335:CST RS12660
gene id: 1121335:CST_RS12660
uniprot id: L7VVU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1121335:CST RS12500
gene id: 1121335:CST_RS12500
uniprot id: L7VN33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1121335:CST RS12505
gene id: 1121335:CST_RS12505
uniprot id: L7VTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1121335:CST RS03280
gene id: 1121335:CST_RS03280
uniprot id: L7VQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS12870
gene id: 1121335:CST_RS12870
uniprot id: L7VVY1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1121335:CST RS11985
gene id: 1121335:CST_RS11985
uniprot id: L7VT11
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1121335:CST RS07620
gene id: 1121335:CST_RS07620
uniprot id: L7VP99
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

1121335:CST RS04760
gene id: 1121335:CST_RS04760
uniprot id: L7VIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS04845
gene id: 1121335:CST_RS04845
uniprot id: L7VIX2
names: Similarity
messages: Belongs to the creatininase superfamily.

1121335:CST RS02870
gene id: 1121335:CST_RS02870
uniprot id: L7VM02
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1121335:CST RS09415
gene id: 1121335:CST_RS09415
uniprot id: L7VLC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1121335:CST RS11225
gene id: 1121335:CST_RS11225
uniprot id: L7VMB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1121335:CST RS03125
gene id: 1121335:CST_RS03125
uniprot id: L7VQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1121335:CST RS06770
gene id: 1121335:CST_RS06770
uniprot id: L7VNR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1121335:CST RS10985
gene id: 1121335:CST_RS10985
uniprot id: L7VRA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS05650
gene id: 1121335:CST_RS05650
uniprot id: L7VNF8
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS08455
gene id: 1121335:CST_RS08455
uniprot id: L7VQ12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1121335:CST RS10840
gene id: 1121335:CST_RS10840
uniprot id: L7VUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1121335:CST RS12240
gene id: 1121335:CST_RS12240
uniprot id: L7VS09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1121335:CST RS06535
gene id: 1121335:CST_RS06535
uniprot id: L7VS18
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1121335:CST RS08460
gene id: 1121335:CST_RS08460
uniprot id: L7VKW5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1121335:CST RS09775
gene id: 1121335:CST_RS09775
uniprot id: L7VU04
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1121335:CST RS12315
gene id: 1121335:CST_RS12315
uniprot id: L7VVJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1121335:CST RS02885
gene id: 1121335:CST_RS02885
uniprot id: L7VLR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1121335:CST RS04500
gene id: 1121335:CST_RS04500
uniprot id: L7VMI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1121335:CST RS07520
gene id: 1121335:CST_RS07520
uniprot id: L7VP75
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS04625
gene id: 1121335:CST_RS04625
uniprot id: L7VMK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1121335:CST RS03030
gene id: 1121335:CST_RS03030
uniprot id: L7VM24
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1121335:CST RS02195
gene id: 1121335:CST_RS02195
uniprot id: L7VPJ3
names: Similarity
messages: Belongs to the peptidase S8 family.

1121335:CST RS10470
gene id: 1121335:CST_RS10470
uniprot id: L7VUF0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS04330
gene id: 1121335:CST_RS04330
uniprot id: L7VQS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1121335:CST RS01180
gene id: 1121335:CST_RS01180
uniprot id: L7VP09
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1121335:CST RS02580
gene id: 1121335:CST_RS02580
uniprot id: L7VPR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1121335:CST RS01690
gene id: 1121335:CST_RS01690
uniprot id: L7VKW1
names: Similarity
messages: Belongs to the peptidase S41A family.

1121335:CST RS00150
gene id: 1121335:CST_RS00150
uniprot id: L7VNE6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1121335:CST RS05145
gene id: 1121335:CST_RS05145
uniprot id: L7VR90
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS11605
gene id: 1121335:CST_RS11605
uniprot id: L7VS10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1121335:CST RS02400
gene id: 1121335:CST_RS02400
uniprot id: L7VLE3
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

1121335:CST RS01525
gene id: 1121335:CST_RS01525
uniprot id: L7VKS6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1121335:CST RS10775
gene id: 1121335:CST_RS10775
uniprot id: L7VM23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS02620
gene id: 1121335:CST_RS02620
uniprot id: L7VM57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1121335:CST RS04165
gene id: 1121335:CST_RS04165
uniprot id: L7VIJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1121335:CST RS09915
gene id: 1121335:CST_RS09915
uniprot id: L7VQL0
names: Similarity
messages: Belongs to the GARS family.

1121335:CST RS02370
gene id: 1121335:CST_RS02370
uniprot id: L7VLZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS04610
gene id: 1121335:CST_RS04610
uniprot id: L7VMU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1121335:CST RS00295
gene id: 1121335:CST_RS00295
uniprot id: L7VKA7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS03525
gene id: 1121335:CST_RS03525
uniprot id: L7VQC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS04460
gene id: 1121335:CST_RS04460
uniprot id: L7VQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121335:CST RS06485
gene id: 1121335:CST_RS06485
uniprot id: L7VS11
names: Similarity
messages: Belongs to the GSP E family.

1121335:CST RS02890
gene id: 1121335:CST_RS02890
uniprot id: L7VQ06
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1121335:CST RS05330
gene id: 1121335:CST_RS05330
uniprot id: L7VJA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1121335:CST RS06940
gene id: 1121335:CST_RS06940
uniprot id: L7VP55
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

1121335:CST RS10215
gene id: 1121335:CST_RS10215
uniprot id: L7VQT1
names: Similarity
messages: Belongs to the transpeptidase family.

1121335:CST RS06550
gene id: 1121335:CST_RS06550
uniprot id: L7VPK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1121335:CST RS11280
gene id: 1121335:CST_RS11280
uniprot id: L7VUW1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121335:CST RS12030
gene id: 1121335:CST_RS12030
uniprot id: L7VSA5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121335:CST RS04365
gene id: 1121335:CST_RS04365
uniprot id: L7VN76
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1121335:CST RS07750
gene id: 1121335:CST_RS07750
uniprot id: L7VPP0
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1121335:CST RS05845
gene id: 1121335:CST_RS05845
uniprot id: L7VJH8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1121335:CST RS11315
gene id: 1121335:CST_RS11315
uniprot id: L7VMC9
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1121335:CST RS08450
gene id: 1121335:CST_RS08450
uniprot id: L7VTA0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1121335:CST RS07985
gene id: 1121335:CST_RS07985
uniprot id: L7VQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS07025
gene id: 1121335:CST_RS07025
uniprot id: L7VSC9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS01555
gene id: 1121335:CST_RS01555
uniprot id: L7VP81
names: Similarity
messages: Belongs to the transpeptidase family.

1121335:CST RS01605
gene id: 1121335:CST_RS01605
uniprot id: L7VP88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1121335:CST RS08000
gene id: 1121335:CST_RS08000
uniprot id: L7VPT6
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1121335:CST RS12170
gene id: 1121335:CST_RS12170
uniprot id: L7VVF7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1121335:CST RS04150
gene id: 1121335:CST_RS04150
uniprot id: L7VMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS01050
gene id: 1121335:CST_RS01050
uniprot id: L7VL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS11145
gene id: 1121335:CST_RS11145
uniprot id: L7VM96
names: Similarity
messages: Belongs to the IMPACT family.

1121335:CST RS00235
gene id: 1121335:CST_RS00235
uniprot id: L7VKT0
names: Similarity
messages: Belongs to the peptidase U62 family.

1121335:CST RS13035
gene id: 1121335:CST_RS13035
uniprot id: L7VT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1121335:CST RS06325
gene id: 1121335:CST_RS06325
uniprot id: L7VJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1121335:CST RS00005
gene id: 1121335:CST_RS00005
uniprot id: L7VKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1121335:CST RS04945
gene id: 1121335:CST_RS04945
uniprot id: L7VMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS05195
gene id: 1121335:CST_RS05195
uniprot id: L7VRA3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1121335:CST RS10335
gene id: 1121335:CST_RS10335
uniprot id: L7VS51
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1121335:CST RS03775
gene id: 1121335:CST_RS03775
uniprot id: L7VM41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS07500
gene id: 1121335:CST_RS07500
uniprot id: L7VSQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1121335:CST RS01005
gene id: 1121335:CST_RS01005
uniprot id: L7VKG6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS11025
gene id: 1121335:CST_RS11025
uniprot id: L7VM73
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1121335:CST RS09595
gene id: 1121335:CST_RS09595
uniprot id: L7VQE4
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1121335:CST RS10425
gene id: 1121335:CST_RS10425
uniprot id: L7VRA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1121335:CST RS07910
gene id: 1121335:CST_RS07910
uniprot id: L7VKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1121335:CST RS11475
gene id: 1121335:CST_RS11475
uniprot id: L7VMG3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1121335:CST RS11180
gene id: 1121335:CST_RS11180
uniprot id: L7VUT6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1121335:CST RS05505
gene id: 1121335:CST_RS05505
uniprot id: L7VP06
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS05430
gene id: 1121335:CST_RS05430
uniprot id: L7VNZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1121335:CST RS07185
gene id: 1121335:CST_RS07185
uniprot id: L7VK52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1121335:CST RS00340
gene id: 1121335:CST_RS00340
uniprot id: L7VKC1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1121335:CST RS02655
gene id: 1121335:CST_RS02655
uniprot id: L7VPS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1121335:CST RS01425
gene id: 1121335:CST_RS01425
uniprot id: L7VLG1
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS02285
gene id: 1121335:CST_RS02285
uniprot id: L7VLA5
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS00640
gene id: 1121335:CST_RS00640
uniprot id: L7VKC3
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS08590
gene id: 1121335:CST_RS08590
uniprot id: L7VKY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1121335:CST RS11995
gene id: 1121335:CST_RS11995
uniprot id: L7VVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1121335:CST RS02950
gene id: 1121335:CST_RS02950
uniprot id: L7VMG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121335:CST RS05950
gene id: 1121335:CST_RS05950
uniprot id: L7VP83
names: Similarity
messages: Belongs to the GSP E family.

1121335:CST RS08335
gene id: 1121335:CST_RS08335
uniprot id: L7VKU5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1121335:CST RS06380
gene id: 1121335:CST_RS06380
uniprot id: L7VPG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1121335:CST RS03305
gene id: 1121335:CST_RS03305
uniprot id: L7VI53
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1121335:CST RS03455
gene id: 1121335:CST_RS03455
uniprot id: L7VLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1121335:CST RS12770
gene id: 1121335:CST_RS12770
uniprot id: L7VSV8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS03640
gene id: 1121335:CST_RS03640
uniprot id: L7VMU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1121335:CST RS05680
gene id: 1121335:CST_RS05680
uniprot id: L7VJF4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1121335:CST RS03425
gene id: 1121335:CST_RS03425
uniprot id: L7VM81
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1121335:CST RS10625
gene id: 1121335:CST_RS10625
uniprot id: L7VRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1121335:CST RS06950
gene id: 1121335:CST_RS06950
uniprot id: L7VPU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1121335:CST RS12850
gene id: 1121335:CST_RS12850
uniprot id: L7VSW8
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS05220
gene id: 1121335:CST_RS05220
uniprot id: L7VRA8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1121335:CST RS08610
gene id: 1121335:CST_RS08610
uniprot id: L7VKY9
names: Similarity
messages: Belongs to the ThiD family.

1121335:CST RS06760
gene id: 1121335:CST_RS06760
uniprot id: L7VJW7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS08825
gene id: 1121335:CST_RS08825
uniprot id: L7VR29
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1121335:CST RS03795
gene id: 1121335:CST_RS03795
uniprot id: L7VMX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

1121335:CST RS07720
gene id: 1121335:CST_RS07720
uniprot id: L7VPD9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121335:CST RS05105
gene id: 1121335:CST_RS05105
uniprot id: L7VJ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1121335:CST RS05665
gene id: 1121335:CST_RS05665
uniprot id: L7VN74
names: Similarity
messages: Belongs to the peptidase S41A family.

1121335:CST RS03375
gene id: 1121335:CST_RS03375
uniprot id: L7VI65
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1121335:CST RS11455
gene id: 1121335:CST_RS11455
uniprot id: L7VSQ6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1121335:CST RS09630
gene id: 1121335:CST_RS09630
uniprot id: L7VQT0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1121335:CST RS12475
gene id: 1121335:CST_RS12475
uniprot id: L7VN13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1121335:CST RS02395
gene id: 1121335:CST_RS02395
uniprot id: L7VM01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1121335:CST RS02780
gene id: 1121335:CST_RS02780
uniprot id: L7VPV8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1121335:CST RS03905
gene id: 1121335:CST_RS03905
uniprot id: L7VIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121335:CST RS03285
gene id: 1121335:CST_RS03285
uniprot id: L7VM63
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS00230
gene id: 1121335:CST_RS00230
uniprot id: L7VGH7
names: Similarity
messages: Belongs to the peptidase U62 family.

1121335:CST RS09905
gene id: 1121335:CST_RS09905
uniprot id: L7VQY7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS01675
gene id: 1121335:CST_RS01675
uniprot id: L7VL43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1121335:CST RS09485
gene id: 1121335:CST_RS09485
uniprot id: L7VQP5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS04630
gene id: 1121335:CST_RS04630
uniprot id: L7VQY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1121335:CST RS12825
gene id: 1121335:CST_RS12825
uniprot id: L7VSW6
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS04480
gene id: 1121335:CST_RS04480
uniprot id: L7VQV3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121335:CST RS04295
gene id: 1121335:CST_RS04295
uniprot id: L7VIM1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1121335:CST RS03310
gene id: 1121335:CST_RS03310
uniprot id: L7VMM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1121335:CST RS09825
gene id: 1121335:CST_RS09825
uniprot id: L7VRS7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121335:CST RS02085
gene id: 1121335:CST_RS02085
uniprot id: L7VHF4
names: Similarity
messages: Belongs to the HsdR family.

1121335:CST RS06975
gene id: 1121335:CST_RS06975
uniprot id: L7VPU8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1121335:CST RS04600
gene id: 1121335:CST_RS04600
uniprot id: L7VMK1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1121335:CST RS06075
gene id: 1121335:CST_RS06075
uniprot id: L7VPA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1121335:CST RS11425
gene id: 1121335:CST_RS11425
uniprot id: L7VRX8
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS11750
gene id: 1121335:CST_RS11750
uniprot id: L7VMM1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1121335:CST RS08880
gene id: 1121335:CST_RS08880
uniprot id: L7VR41
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1121335:CST RS12830
gene id: 1121335:CST_RS12830
uniprot id: L7VN88
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1121335:CST RS04665
gene id: 1121335:CST_RS04665
uniprot id: L7VIT7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1121335:CST RS12270
gene id: 1121335:CST_RS12270
uniprot id: L7VSH8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121335:CST RS12285
gene id: 1121335:CST_RS12285
uniprot id: L7VS21
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1121335:CST RS05920
gene id: 1121335:CST_RS05920
uniprot id: L7VP39
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1121335:CST RS10695
gene id: 1121335:CST_RS10695
uniprot id: L7VRF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1121335:CST RS01400
gene id: 1121335:CST_RS01400
uniprot id: L7VLF8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1121335:CST RS02590
gene id: 1121335:CST_RS02590
uniprot id: L7VHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1121335:CST RS09565
gene id: 1121335:CST_RS09565
uniprot id: L7VQR4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1121335:CST RS05135
gene id: 1121335:CST_RS05135
uniprot id: L7VNQ0
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS09790
gene id: 1121335:CST_RS09790
uniprot id: L7VRS1
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS11090
gene id: 1121335:CST_RS11090
uniprot id: L7VUR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1121335:CST RS10380
gene id: 1121335:CST_RS10380
uniprot id: L7VR97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1121335:CST RS10510
gene id: 1121335:CST_RS10510
uniprot id: L7VS73
names: Similarity
messages: Belongs to the TlyA family.

1121335:CST RS13040
gene id: 1121335:CST_RS13040
uniprot id: L7VNC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1121335:CST RS12085
gene id: 1121335:CST_RS12085
uniprot id: L7VMT6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1121335:CST RS11290
gene id: 1121335:CST_RS11290
uniprot id: L7VMC4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1121335:CST RS11460
gene id: 1121335:CST_RS11460
uniprot id: L7VRJ7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1121335:CST RS10735
gene id: 1121335:CST_RS10735
uniprot id: L7VR37
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS07645
gene id: 1121335:CST_RS07645
uniprot id: L7VPA5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1121335:CST RS11325
gene id: 1121335:CST_RS11325
uniprot id: L7VUX2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121335:CST RS00170
gene id: 1121335:CST_RS00170
uniprot id: L7VK23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1121335:CST RS09540
gene id: 1121335:CST_RS09540
uniprot id: L7VRJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1121335:CST RS04255
gene id: 1121335:CST_RS04255
uniprot id: L7VQQ6
names: Subcellular Location Annotation
messages: Membrane

1121335:CST RS00965
gene id: 1121335:CST_RS00965
uniprot id: L7VKP5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1121335:CST RS07675
gene id: 1121335:CST_RS07675
uniprot id: L7VSU4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1121335:CST RS04790
gene id: 1121335:CST_RS04790
uniprot id: L7VMP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1121335:CST RS05295
gene id: 1121335:CST_RS05295
uniprot id: L7VRF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane